Austin journal of pulmonary and respiratory medicine最新文献

{"title":"Use of the AGobi All-in-One Airway Stabilizing Device During Fiberoptic Bronchoscopy: A Case Study Report","authors":"Ghobrial Vg, A. Schon, D. Childress","doi":"10.4172/2161-105x.1000472","DOIUrl":"https://doi.org/10.4172/2161-105x.1000472","url":null,"abstract":"Airway management during endoscopy is highly critical, and this is particularly true in older patients with complex medical issues. Over the course of the last few decades, tremendous advances in various airway stabilization devices used during endoscopic procedures have occurred. This includes not only laryngeal masks but a variety of extraglottic devices as well. Identifying airway stabilization devices that offer patient safety, patient comfort and ease-of-use while promoting high quality results remains a continual process. With this in mind, a case study presentation is provided involving a complicated elderly patient undergoing fiberoptic bronchoscopy that utilized the AGobi All-inOne Airway Stabilization device. The case experience will highlight the advantages of this supraglottic airway device while an examination of the research literature will discuss its potential limitations. Based on this case study, the use of this device in fiberoptic bronchoscopy and in a number of other situations where airway stabilization is needed is supported. In addition, the case study also supports further study of the AGobi All-in-One Airway Stabilizing device in comparison to other airway stabilizing options in specific patient scenarios. *Corresponding author: Victor G. Ghobrial, Associates/Respiratory Medicine, Bradenton, Florida, USA, Tel: (941) 746-7444; Fax: (941) 746-1777; E-mail: victorghobrial@ymail.com Received August 23, 2018; Accepted September 12, 2018; Published September 18, 2018 Citation: Ghobrial VG, Schon A, Childress D (2018) Use of the AGobi All-in-One Airway Stabilizing Device During Fiberoptic Bronchoscopy: A Case Study Report. J Pulm Respir Med 8: 472. doi: 10.4172/2161-105X.1000472 Copyright: ©2018 Ghobrial VG, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.","PeriodicalId":90449,"journal":{"name":"Austin journal of pulmonary and respiratory medicine","volume":"14 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2018-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"81883960","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Patients with Chronic Obstructive Pulmonary Disease Have a High Prevalence of Osteopenia and Osteoporosis associated with the Worst Degrees of Pulmonary Function and Prognosis","authors":"D. Costa","doi":"10.4172/2161-105X.1000442","DOIUrl":"https://doi.org/10.4172/2161-105X.1000442","url":null,"abstract":"Introduction/Background: Chronic obstructive pulmonary disease (COPD) is associated with osteoporosis and vertebral fractures. It is still unclear whether the presence of fractures and changes in bone mineral density (BMD) are associated with disease severity and prognosis. The aim of this study was to evaluate low BMD, and morphometric vertebral fractures (MVF) in patients with COPD compared with two control groups and correlate these parameters with indices of COPD severity (FEV1 and GOLD) and prognosis (BODE). Methodology: This was a cross-sectional study in COPD patients (disease group, DG) that undergone BMD and vertebral fracture assessment (VFA). Two control groups were used, one group of smokers individuals without COPD (smokers group, SG), and another group of healthy never smokers individuals (never smokers group, NSG). Results: DG comprised 121 patients (65 women, mean age 67.9 ± 8.6 years). Altered BMD was observed in 88.4% of the patients in the DG which was more prevalent when compared to control groups (p<0.001). The BMD values were lower in the DG than in controls (p<0.05). BMD was associated with the worst degree of obstruction (FEV1), GOLD, and BODE (p<0.05). The prevalence of MVF was high (57.8%) and greater than that in the SG (23.8%), and NSG (14.8%; p<0.001). The prevalence of fractures was not associated with FEV1, GOLD, or BODE. Conclusions: This study showed a high prevalence of low BMD in COPD patients and an association with a worse degree of FEV1, GOLD, and BODE. MVF in patients with COPD were also higher but were not associated with disease gravity and prognosis.","PeriodicalId":90449,"journal":{"name":"Austin journal of pulmonary and respiratory medicine","volume":"59 1","pages":"1-5"},"PeriodicalIF":0.0,"publicationDate":"2018-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"72572888","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Meta-Analysis of P73 Polymorphism and Risk of Non-Small Cell Lung Cancer","authors":"Xiangsong Cheng, Haiyang Liu, Yong-na Song, Yunxia An, Xuan Weixia, Z. Wang, Zhiwei Xu, Nan Wei, Xiaoju Zhang","doi":"10.4172/2161-105X.1000446","DOIUrl":"https://doi.org/10.4172/2161-105X.1000446","url":null,"abstract":"Background: The relationship between p73 gene G4C14-to-A4T14 polymorphism and non-small cell lung cancer risk is unclear. Now we performed a meta-analysis to clarify the association of p73 polymorphism with nonsmall cell lung cancer.Methods: To assess the association between p73 polymorphism and non-small cell lung cancer deeply, we searched Pubmed, Embase, CNKI, Wanfang and CBM databases. All analyses were done using RevMan 5.3 software which provided by the Cochrane Collaboration and Stata version 12.0. The statistical heterogeneity among studies was assessed with the chi-square-based Q test. We used the random effects model as well as the fixed effects model to calculate the pooled ORs.Results: Our meta-analysis included 6 studies with a total of 1658 patients with non-small lung cancer and 2328 cancer-free control subjects. In all comparisons, we find none of genetic models shows significant relation with the risk of non-small lung cancer (recessive model: OR: 1.16, 95%CI: 0.94-1.43; dominant model: OR: 0.63, 95%CI: 0.37-1.06; co-dominant model: OR: 1.63, 95%CI: 0.94-2.83; allelic model: OR: 1.20, 95%CI: 0.98-1.48). However, when we proceeded to subgroup analysis according country, significantly increased risk was observed in a recessive models (OR: 1.35, 95%CI: 1.15-1.59), in a co-dominant model: (OR: 2.49, 95%CI: 1.76-3.53), in an allelic model (OR, 1.41, 95%CI, 1.24-1.61). Significantly decreased risk was observed in a dominant model (OR: 0.42, 95%CI: 0.30-0.59).Conclusions: Our results indicate that p73 gene G4C14-to-A4T14 polymorphism is associated with the risk of non-small cell lung cancer in China. However, a large gene-to-environment research is required to confirm this conclusion.","PeriodicalId":90449,"journal":{"name":"Austin journal of pulmonary and respiratory medicine","volume":"18 1","pages":"1-7"},"PeriodicalIF":0.0,"publicationDate":"2018-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"76287552","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Particulate Matter and Respiratory Diseases: How Far Have We Gone?","authors":"W. J, Chen S, Zhu M, Miao C, S. Y, He H","doi":"10.4172/2161-105X.1000465","DOIUrl":"https://doi.org/10.4172/2161-105X.1000465","url":null,"abstract":"Air pollution is a potential threat to public health worldwide, especially in South Asia. The Global Burden of Diseases, Injuries, and Risk Factors Study 2016 (GBD 2016) reported that most of global deaths attributable to ambient particulate matter occurred in China and India. Particulate matter (PM), as the main air pollutant, is receiving increasing attention due to its specific biological properties. PM is a complicated mixture and varies in sizes, compositions and sources. Increasing epidemiological studies have shown that both short- and long-term PM exposure are associated with the morbidity and mortality of respiratory diseases, including chronic obstructive pulmonary disease (COPD), asthma, lung cancer, and pneumonia, especially in the elderly and children. Several potential biological mechanisms have been proposed to explain the adverse effect of PM on the respiratory diseases, including oxidant stress, pro-inflammation, epigenetic modifications, DNA damage and carcinogenesis. However, there are still some contradictions with regard to the role of PM in the development of these respiratory diseases. Thus, this review made a summary of results from epidemiological studies about the association between PM and COPD, asthma, lung cancer, and pneumonia, and elucidated its potential biological mechanisms.","PeriodicalId":90449,"journal":{"name":"Austin journal of pulmonary and respiratory medicine","volume":"8 1","pages":"1-7"},"PeriodicalIF":0.0,"publicationDate":"2018-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"77716085","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"An Uncommon Cause of Bronchiectasis: A Case Report","authors":"A. ulQadir, A. Afsar, M. Aslam","doi":"10.4172/2161-105x.1000467","DOIUrl":"https://doi.org/10.4172/2161-105x.1000467","url":null,"abstract":"Bronchiectasis is a common respiratory condition and has a number of causes. One of the causes of bronchiectasis is immunoglobUIin deficiency. Common variable immunodeficiency (CVID) is the most common symptomatic primary immunodeficiency disorder characterized by an increased incidence of recurrent infections, autoimmune phenomena and neoplastic diseases. This article describes a 37-year-old gentleman who was diagnosed as a case of CVID on the basis of recurrent respiratory tract infections and laboratory findings. He improved with monthly intravenous immunoglobUIins (IVIG). The diagnosis is often difficUIt and delayed but shoUId be considered for patients with recurrent infections. *Corresponding author: Aziz UI Qadir, Department of PUImonary Medicine, POF Hospital, Wah Medical College, Wah Cantt, Pakistan, Tel: 0092-3445515989; E-mail: azizUIqadir@gmail.com Received JUIy 27, 2018; Accepted August 17, 2018; Published August 24, 2018 Citation: UI Qadir A, Afsar A, Aslam M (2018) An Uncommon Cause of Bronchiectasis: A Case Report. J PUIm Respir Med 8: 467. doi: 10.4172/2161105X.1000467 Copyright: ©2018 UI Qadir A, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.","PeriodicalId":90449,"journal":{"name":"Austin journal of pulmonary and respiratory medicine","volume":"47 28 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2018-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"82264791","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Successful Medical Treatment of Pulmonary Mucormycosis in Diabetic Patients","authors":"W. Feki, S. Sellami, S. Charfi, W. Ketata, S. M’saad, N. Bahloul, H. Ayadi, S. Kammoun","doi":"10.4172/2161-105X.1000444","DOIUrl":"https://doi.org/10.4172/2161-105X.1000444","url":null,"abstract":"Pulmonary mucormycosis is a relatively uncommon infection that is mostly observed among diabetic patients. We present here three cases of pulmonary mucormycosis as the cause of non-resolving pneumonia in diabetic patients. The goals of our review are to better characterize the population at risk, presenting symptoms, radiological appearance, diagnostic methods and to demonstrate the efficacy of medical therapy.","PeriodicalId":90449,"journal":{"name":"Austin journal of pulmonary and respiratory medicine","volume":"89 1","pages":"1-5"},"PeriodicalIF":0.0,"publicationDate":"2018-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"89675494","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Lung Cancer Presented as Skin Metastases: A Case Report","authors":"A. Kumar, P. Aggarwal","doi":"10.4172/2161-105x.1000470","DOIUrl":"https://doi.org/10.4172/2161-105x.1000470","url":null,"abstract":"Lung cancer with skin metastasis is rare entity and associated with poor prognosis. It can easily lead to misdiagnosis and mistreatments when it presents with skin involvement, so early recognition of the skin metastasis is important as it may be the presenting sign of an underlying malignancy. Most common sites for skin metastasis are chest, back, abdomen, head, and neck and they are usually single or multiple painless nodules. However, the skin metastasis in squamous and small cell lung carcinoma is uncommon and it carries rapidly fatal clinical outcome. We present a rare case of non-small cell lung cancer presenting as rapidly growing skin metastasis. *Corresponding author: Arjun Kumar, Department of Pulmonary Medicine, Government Medical College and Hospital, Chandigarh, India, Tel: 8054809188; E-mail: aknlnegi@gmail.com Received August 30, 2018; Accepted September 06, 2018; Published September 13, 2018 Citation: Kumar A, Aggarwal P (2018) Lung Cancer Presented as Skin Metastases: A Case Report. J Pulm Respir Med 8: 470. doi: 10.4172/2161-105X.1000470 Copyright: © 2018 Kumar A, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.","PeriodicalId":90449,"journal":{"name":"Austin journal of pulmonary and respiratory medicine","volume":"66 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2018-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"84036161","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effectiveness of a Pulmonary Rehabilitation Program on Changes in Heart Rate Variability and Physical Performance in Chronic Obstructive Pulmonary Disease","authors":"Szucs B, Petrekanits M, Varga J","doi":"10.4172/2161-105X.1000474","DOIUrl":"https://doi.org/10.4172/2161-105X.1000474","url":null,"abstract":"Changes in autonomic regulation are evaluated in COPD patients by using heart rate variability (HRV) in rehabilitation. Our aim was to evaluate the presence of autonomic dysfunction and to assess the effect of a rehabilitation program. R-R intervals were measured for 6 minutes in 36 patients (16 female; 20 male) before and after an inpatient pulmonary rehabilitation program that included 30 minutes of respiratory training, chest wall mobilization, learning controlled breathing techniques, inhalation, expectoration and personalized training. Ectopic beats were eliminated. Parameters used: minimal pulse (p.min), average pulse (p.avg), maximal pulse (p.max), maximum-minimum pulse difference (p.max-p.min). Long-term continuous RR intervals (stda), standard deviation of instantaneous beat-to-beat variability (stdb), the number of pairs of adjacent NN intervals differing by more than 50 ms divided by the total number of all NN intervals (pNN50). Spectral analysis provided the low-frequency/high-frequency ratio (LF/HF). HRV showed decreased p.max-p.min (15.78 ± 9.2 bpm), depressed dynamics (stda: 39.63 ± 33.5; stdb: 22.72 ± 35.84) with sympathetic overload (pNN50:3.17 ± 5.24, LF/HF: 169.52 ± 208.83), heavy parasympathetic modulation (pNN50:5.51 ± 5.59, LF/HF: 27.28 ± 13.12) in severe COPD patients. Rehabilitation resulted in lowered p.min-p.max (12.5 ± 9.01 bpm), overdepressed dynamics (stda: 34.56 ± 35.97; stdb: 20.88 ± 41.5) strong sympathetic overload (pNN50:3.33 ± 6.76, LF/HF: 252.01 ± 351.16). Patients showed abnormal physiological response in resting autonomic regulation. The rehabilitation resulted in improvement in overall status, autonomic balance. *Corresponding author: Janos Varga, Department of Pulmonary Rehabilitation, National Koranyi Institute for Pulmonology, Budapest, Hungary, Tel: +3613913374; Fax: +3613913285; E-mail: varga@koranyi.hu Received September 25, 2018; Accepted September 28, 2018; Published October 04, 2018 Citation: Szucs B, Petrekanits M, Varga J (2018) Effectiveness of a Pulmonary Rehabilitation Program on Changes in Heart Rate Variability and Physical Performance in Chronic Obstructive Pulmonary Disease. J Pulm Respir Med 8: 474. doi: 10.4172/2161-105X.1000474 Copyright: ©2018 Szucs B, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.","PeriodicalId":90449,"journal":{"name":"Austin journal of pulmonary and respiratory medicine","volume":"11 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2018-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"76819065","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Diffuse Alveolar Hemorrhage after Anabolic Steroid Use: A Case Report","authors":"B. GómezRodríguez, R. Ja","doi":"10.4172/2161-105x.1000473","DOIUrl":"https://doi.org/10.4172/2161-105x.1000473","url":null,"abstract":"Introduction: Corticosteroids have an important role in multiples physiological mechanisms, including carbohydrate metabolism, protein catabolism and a potent anti-inflammatory activity that made them basic to the treatment of a large number of autoimmune diseases. Anabolic steroid treatment has been associated with a large number of side effects: Impaired hepatic function, hypotrophic hypogonadism, cardiac involvement, thrombosis development, etc. However, there are few cases reported in the medical literature of diffuse alveolar haemorrhage secondary to this cause. In recent years there has been an increase in the use of corticosteroids in an abusive way for non-medical purposes, specifically in the field of bodybuilding, with the aim of gaining muscle mass quickly and which is worrying as well as the adverse effects previously mentioned, by the disconcerting of the long-term adverse effects. Presentation of the Case: We present the case of a young male bodybuilder patient who presented diffuse alveolar haemorrhage due to several cycles of anabolic steroid treatment. The clinical picture began with dyspnea and hemoptysis associated with an X-ray and chest CT with compatible infiltrates. The patient presented a favorable response to the administration of corticosteroids in high doses and after the withdrawal of the anabolic steroids the normalization of the imaging tests took place, without presenting subsequent alterations in the pulmonary function. Conclusions: We consider that it is important to keep in mind the diffuse alveolar haemorrhage as a complication associated with the use of anabolic steroids and it must be taken into account that the patient is precocious with dyspnea and hemoptysis. *Corresponding author: Belen Gomez Rodriguez, Hospital Universitario Virgen del Rocio, Seville, Spain, Tel: 658196605; E-mail: bgrneumo@gmail.com Received September 10, 2018; Accepted September 28, 2018; Published October 04, 2018 Citation: Rodríguez GB, Portal JAR (2018) Diffuse Alveolar Hemorrhage after Anabolic Steroid Use: A Case Report. J Pulm Respir Med 8: 473. doi: 10.4172/2161105X.1000473 Copyright: ©2018 Rodríguez GB, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.","PeriodicalId":90449,"journal":{"name":"Austin journal of pulmonary and respiratory medicine","volume":"10 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2018-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"74451283","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A Study of Clinical-Radiological, Pathological Profile and Treatment Outcome of Patients Admitted to a Tertiary Care Center with Haemoptysis","authors":"A. P. N. Aldave","doi":"10.4172/2161-105X.1000438","DOIUrl":"https://doi.org/10.4172/2161-105X.1000438","url":null,"abstract":"","PeriodicalId":90449,"journal":{"name":"Austin journal of pulmonary and respiratory medicine","volume":"61 1","pages":"1-1"},"PeriodicalIF":0.0,"publicationDate":"2017-12-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"88178023","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}