Diffuse Alveolar Hemorrhage after Anabolic Steroid Use: A Case Report
B. GómezRodríguez, R. Ja
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引用次数: 2
Abstract
Introduction: Corticosteroids have an important role in multiples physiological mechanisms, including carbohydrate metabolism, protein catabolism and a potent anti-inflammatory activity that made them basic to the treatment of a large number of autoimmune diseases. Anabolic steroid treatment has been associated with a large number of side effects: Impaired hepatic function, hypotrophic hypogonadism, cardiac involvement, thrombosis development, etc. However, there are few cases reported in the medical literature of diffuse alveolar haemorrhage secondary to this cause. In recent years there has been an increase in the use of corticosteroids in an abusive way for non-medical purposes, specifically in the field of bodybuilding, with the aim of gaining muscle mass quickly and which is worrying as well as the adverse effects previously mentioned, by the disconcerting of the long-term adverse effects. Presentation of the Case: We present the case of a young male bodybuilder patient who presented diffuse alveolar haemorrhage due to several cycles of anabolic steroid treatment. The clinical picture began with dyspnea and hemoptysis associated with an X-ray and chest CT with compatible infiltrates. The patient presented a favorable response to the administration of corticosteroids in high doses and after the withdrawal of the anabolic steroids the normalization of the imaging tests took place, without presenting subsequent alterations in the pulmonary function. Conclusions: We consider that it is important to keep in mind the diffuse alveolar haemorrhage as a complication associated with the use of anabolic steroids and it must be taken into account that the patient is precocious with dyspnea and hemoptysis. *Corresponding author: Belen Gomez Rodriguez, Hospital Universitario Virgen del Rocio, Seville, Spain, Tel: 658196605; E-mail: bgrneumo@gmail.com Received September 10, 2018; Accepted September 28, 2018; Published October 04, 2018 Citation: Rodríguez GB, Portal JAR (2018) Diffuse Alveolar Hemorrhage after Anabolic Steroid Use: A Case Report. J Pulm Respir Med 8: 473. doi: 10.4172/2161105X.1000473 Copyright: ©2018 Rodríguez GB, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
合成代谢类固醇使用后弥漫性肺泡出血1例报告
糖皮质激素在多种生理机制中发挥重要作用,包括碳水化合物代谢、蛋白质分解代谢和有效的抗炎活性,使其成为治疗大量自身免疫性疾病的基础。合成代谢类固醇治疗有许多副作用:肝功能受损、性腺功能减退、心脏受累、血栓形成等。然而,医学文献中很少报道继发于该病因的弥漫性肺泡出血。近年来,出于非医疗目的滥用皮质类固醇的情况有所增加,特别是在健美领域,目的是迅速增加肌肉质量,这与前面提到的不利影响一样令人担忧,因为长期不利影响令人不安。病例介绍:我们提出的情况下,一个年轻的男性健美运动员病人谁提出弥漫性肺泡出血由于几个周期的合成代谢类固醇治疗。临床表现以呼吸困难和咯血开始,x线和胸部CT显示相容浸润。患者对高剂量皮质类固醇治疗反应良好,停用合成代谢类固醇后影像学检查恢复正常,肺功能未出现后续改变。结论:我们认为,重要的是要记住弥漫性肺泡出血是与使用合成代谢类固醇相关的并发症,必须考虑到患者患有呼吸困难和咯血的早熟。*通讯作者:Belen Gomez Rodriguez,西班牙塞维利亚罗西奥圣母大学医院,电话:658196605;邮箱:bgrneumo@gmail.com 2018年9月10日收稿;2018年9月28日录用;引用文献:Rodríguez GB, Portal JAR(2018)合成代谢类固醇使用后弥漫性肺泡出血:一例报告。[J] .中华肺科杂志8:473。doi: 10.4172 / 2161105 x.1000473版权所有:©2018 Rodríguez GB, et al。这是一篇根据知识共享署名许可协议发布的开放获取文章,该协议允许在任何媒体上不受限制地使用、分发和复制,前提是要注明原作者和来源。
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