BMC Veterinary Research最新文献

{"title":"Morphometric assessment of the femoral trochlea, patella and patellar ligament in small breed dogs with and without grade II medial patellar luxation.","authors":"Rudi Barthmann, Lars Fh Theyse","doi":"10.1186/s12917-026-05816-x","DOIUrl":"https://doi.org/10.1186/s12917-026-05816-x","url":null,"abstract":"<p><strong>Background: </strong>Medial patellar luxation is a common orthopedic condition in small breed dogs, though its etiology remains poorly understood. The aim of this study was to assess the morphometry of the femoral trochlea, patella and patellar ligament in small breed dogs with and without grade 2 medial patellar luxation. This retrospective study evaluated small breed dogs weighing ≤ 15 kg including 80 stifles with Grade 2 MPL and 80 controls. The femoral trochlear length to patellar length ratio (TL: PL), trochlear curvature to condylar curvature ratio (TC: CC) and patellar ligament length to patellar length ratio (PLL: PL) were assessed. In addition, these parameters were determined comparing dogs with and without a chondrodysplastic phenotype. T-tests and ANOVA were used for statistical analysis.</p><p><strong>Results: </strong>The TL: PL ratio was increased in dogs with grade II MPL compared to controls with 1.7 ± 0.3 and 1.6 ± 0.2. (p<.001), respectively. This indicates an increased length of the trochlea. No differences were found in the TC: CC and PLL: PL ratios between both groups. Within the grade II MPL group, there was an increased PLL: PL ratio (2.0 ± 0.2; 1.9 ± 0.2; p=.002) in dogs with chondrodysplastic phenotype in comparison with non-chondrodysplastic phenotype. A decreased femoral trochlear length, or a decreased curvature of the femoral trochlea does not seem to be related to grade II patella luxation in small breed dogs. In dogs with a chondrodysplastic phenotype the relatively longer patellar ligament could play a role in the development of grade II MPL.</p><p><strong>Conclusion: </strong>Trochlear length and curvature did not seem to be related to the development of grade II MPL. In dogs with a chondrodysplastic phenotype, grade II MPL could be related to a longer patellar ligament.</p>","PeriodicalId":9041,"journal":{"name":"BMC Veterinary Research","volume":"22 1","pages":""},"PeriodicalIF":3.1,"publicationDate":"2026-08-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13488211/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148788023","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Guttural pouch tympany or empyema in 38 ٍStraight Egyptian Arabian foals: clinical presentation, diagnostic features and outcome.","authors":"Ashraf M Abu-Seida, Hanaa A E Asfour, Mohammad A H Abdulredha, Mohamed K Derbala","doi":"10.1186/s12917-026-05810-3","DOIUrl":"https://doi.org/10.1186/s12917-026-05810-3","url":null,"abstract":"&lt;p&gt;&lt;strong&gt;Background: &lt;/strong&gt;As a breed, Straight Egyptian Arabian horses are susceptible to many disorders that mostly affect the head, such as guttural pouch (GP) tympany and empyema. This retrospective study evaluated the findings of clinical examination, ultrasonography, endoscopy, laboratory analyses and outcome of treatment of 38 Straight Egyptian Arabian foals with GP tympany and empyema.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Methods: &lt;/strong&gt;Data from medical records of foals diagnosed with GP tympany or empyema over a 2-year period (2024-2025) were reviewed. Foals with verified GP tympany or empyema who had complete medical records and had not previously received antibiotics and/or corticosteroids met the inclusion criteria. Foals with incomplete records, unconfirmed diagnosis or concurrent diseases likely to influence the evaluated variables were excluded. Outcomes of treatment (recovery and recurrence) were compared with diagnostic features and treatment modalities. The data were statistically analyzed.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Results: &lt;/strong&gt;Out of 237 foals presented with various disorders, 38 foals had GP tympany and empyema, representing 16.03% of the total examined foals. Out of 38 foals with GP tympany and empyema, there were 29 females (77.8%) and 9 males (22.2%). The frequencies of GP tympany and empyema were significantly higher in the first month of life (47.4%) than the 8-9-month period (10.5% ((P &lt; 0.05). Bilateral GP tympany and empyema were recorded in 30 foals (78.9%). While eight cases (21.1%) had unilateral GP tympany and/or empyema. The studied foals had GP tympany (25/38, 65.8%) or GP empyema (13/38, 34.2%). Out of 25 foals with GP tympany, five foals (20%) had complicated GP tympany with microbial infections. Ultrasonography examination of the GP tympany and empyema had a diagnostic value in 15.8% of the cases. In foals with GP tympany, endoscopy revealed distention of the afflicted GP with air, dorsal or lateral nasopharyngeal compression, and a stretched, thinning, pale mucosal lining. However, mucopurulent material and hyperemic, uneven GP mucosa were observed in one or both GPs in foals with GP empyema. Foals with uncomplicated GP tympany had normal hematology and serum chemistry. While foals with GP empyema and complicated GP tympany exhibited mild to moderate leukocytosis, neutrophilia with left shift in severe infection, hyperfibrinogenemia, mild hyperproteinemia, mild hyperglobulinemia (in chronic cases), mild hypoalbuminemia (in chronic cases), and increased serum amyloid A. Out of 38 foals with GP tympany and empyema, 18 foals (47.4%) had microbial infections. The microbial isolates were double mixed infections (50%) and triple mixed infection (50%). The most commonly isolated bacteria were α-hemolytic S. equi ssp. equi (13/18, 72.2%). Out of 36 treated foals, 33 foals (91.7%) with GP tympany and empyema recovered after 4-6 weeks of treatment by placement of a transnasal Foley catheter under the guidance of endoscopy with repeated la","PeriodicalId":9041,"journal":{"name":"BMC Veterinary Research","volume":"22 1","pages":""},"PeriodicalIF":3.1,"publicationDate":"2026-08-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13491969/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148787988","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Transcriptome profiling analysis of heat-adapted and heat-sensitive breeder hen jejunal mucosal tissues in response to acute heat stress.","authors":"Yongcai Zhu, Satoshi Kubota, Phocharapon Pasri, Sitthipong Rakngam, Shenglin Yang, Sutisa Khempaka","doi":"10.1186/s12917-026-05835-8","DOIUrl":"10.1186/s12917-026-05835-8","url":null,"abstract":"<p><strong>Background: </strong>Heat stress impairs intestinal integrity in poultry, compromising nutrient digestion and absorption. Nevertheless, the individual variation in heat tolerance suggests distinct molecular responses that are still not well understood.</p><p><strong>Materials and methods: </strong>This study investigated the molecular basis of differential heat tolerance by comparing jejunal transcriptomes in heat-adapted (HA) and heat-sensitive (HS) breeder hens under acute heat stress (36 °C for a 6-h). Fifty 28-week-old hens were randomly allocated to the HA and HS groups (25 hens each). After exposure to acute heat stress for 6 h, the respiratory rate and cloacal temperature were measured, and jejunal mucosal samples were collected for RNA sequencing (RNA-seq).</p><p><strong>Results: </strong>The results indicated that, under acute heat stress, the respiratory rates and cloacal temperatures of HS hens were significantly higher than those of HA hens (P = 0.002). RNA-seq analysis identified 284 differentially expressed genes (DEGs), with 155 genes upregulated and 129 downregulated in the HS group compared to the HA group. Gene Ontology analysis revealed significant enrichment in 555 GO terms. Kyoto Encyclopedia of Genes and Genomes pathway analysis identified five pathways that were enriched in upregulated DEGs (VEGF signaling pathway, MAPK signaling pathway, steroid biosynthesis, neuroactive ligand-receptor interaction, and cell cycle) and one pathway enriched in downregulated DEGs (cell adhesion molecules). Protein-protein interaction network identified key genes (PLK1, CDC7, CDC20, HSPA2, IL6, LBFABP, SLC6A19, and SLC2A2), involved in cell division, immune function, energy and lipid metabolism, as well as organic acid, glucose, and amino acids transport.</p><p><strong>Conclusions: </strong>These findings suggest that acute heat stress differentially affects intestinal function in HA and HS hens, potentially through alterations in cell division, immune function, energy and lipid metabolism, and organic acid and glucose transport mechanisms. The identified DEGs and pathways offer valuable insight into the molecular basis of heat stress susceptibility and may inform nutritional or management strategies to enhance poultry resilience.</p>","PeriodicalId":9041,"journal":{"name":"BMC Veterinary Research","volume":"22 1","pages":""},"PeriodicalIF":3.1,"publicationDate":"2026-08-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13602669/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149036339","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Colloid mill modified zein suspension technology for plant protein rich bird food: first clutch performance compared with egg based food in fiorino canaries.","authors":"Ercan Mevliyaoğulları","doi":"10.1186/s12917-026-05838-5","DOIUrl":"10.1186/s12917-026-05838-5","url":null,"abstract":"<p><strong>Background: </strong>The present study evaluated a technology-driven approach for producing a plant-protein-rich bird food based on colloid-mill-modified zein suspension and compared its first-clutch reproductive performance with an egg-based food in Fiorino canaries. The formulation strategy was informed by literature showing that intensive mechanical processing can reduce aggregation and improve matrix homogeneity in zein-rich maize protein systems [1]. ZEIN16 was therefore evaluated primarily as a processed-zein technology platform and bird-food prototype.</p><p><strong>Methods: </strong>Forty first-time Fiorino canary pairs were allocated to two isoprotein dietary groups, with 20 pairs per group: EGG16, an egg-based bird food, and ZEIN16, a modified zein suspension-based bird food. Both diets contained approximately 16% crude protein and were fed for 12 weeks before pairing. ZEIN16 was produced using colloid milling as the zein-modification step, guided by zein-processing literature. Each breeding pair was the independent experimental unit. First-clutch egg number, hatched chick number, unhatched eggs, and hatchability were analysed using pair-level data; pooled hatchability was treated as descriptive egg-level information.</p><p><strong>Results: </strong>EGG16 produced significantly more eggs than ZEIN16 (3.65 ± 0.75 vs. 2.90 ± 0.55 eggs per pair; Mann-Whitney p = 0.0012; mean difference = 0.75 eggs per pair, 95% CI 0.33 to 1.17; Cliff's delta = 0.55). Hatched chick number was numerically higher in EGG16 (2.95 ± 1.15 vs. 2.50 ± 0.69 chicks per pair), but the complete-data comparison did not reach the 5% significance threshold (p = 0.0627; mean difference = 0.45 chicks per pair, 95% CI -0.16 to 1.06). Individual hatchability did not differ between groups (79.42 ± 25.42% vs. 86.25 ± 17.79%; p = 0.5759). Descriptive pooled hatchability was 80.82% for EGG16 and 86.21% for ZEIN16 (Fisher exact p = 0.4850). Supporting count and binomial sensitivity analyses did not change the qualitative interpretation.</p><p><strong>Conclusions: </strong>EGG16 improved first-clutch egg production. ZEIN16 did not show a statistically detectable reduction in hatchability after eggs were laid, but equivalence or non-inferiority to EGG16 was not tested. ZEIN16 should therefore be positioned as a preliminary plant-protein-rich bird egg food analogue produced through colloid-mill-based zein suspension technology, rather than as a reproductive replacement for egg-based food.</p>","PeriodicalId":9041,"journal":{"name":"BMC Veterinary Research","volume":"22 1","pages":""},"PeriodicalIF":3.1,"publicationDate":"2026-08-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13659948/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149163724","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Retraction Note: Nano-selenium supplementation: improving growth, digestibility and mineral absorption in freshwater fish, Catla catla.","authors":"Nisar Ahmad, Syed Makhdoom Hussain, Shafaqat Ali, Muhammad Farrukh Tahir, Pallab K Sarker, Mudassar Shahid","doi":"10.1186/s12917-026-05830-z","DOIUrl":"10.1186/s12917-026-05830-z","url":null,"abstract":"","PeriodicalId":9041,"journal":{"name":"BMC Veterinary Research","volume":"22 1","pages":""},"PeriodicalIF":3.1,"publicationDate":"2026-08-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13476929/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148758955","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Giardia duodenalis and Entamoeba spp.: Coprological and antibody-based approaches across farm animals in Egypt.","authors":"Nagwa I Toaleb, Kadria N Abdel Megeed, Dina Aboelsoued","doi":"10.1186/s12917-026-05801-4","DOIUrl":"10.1186/s12917-026-05801-4","url":null,"abstract":"<p><p>Giardia duodenalis (syn. G. lamblia, G. intestinalis) and Entamoeba spp. are enteric protozoans causing gastrointestinal illnesses in humans and animals worldwide. This study aimed to determine the prevalence of Giardia and Entamoeba infections in farm animals in Egypt, and to develop an in-house sandwich ELISA for their coproantigen detection. In this study, a total of 2674 fecal samples were collected from buffaloes (N = 875), cattle (N = 770), sheep (N = 520), and goats (N = 509) from different age groups across five governorates. All samples were examined using conventional microscopical methods. Using microscopy, Giardia and Entamoeba infections were detected in 626/2674 (23.4%) and 457/2674 (17.1%) of samples, respectively, and sheep showed the highest infection rates by both parasites (44.6% and 28.8% for Giardia and Entamoeba, respectively). Representative isolates were molecularly characterized, to confirm parasite identity prior to antigen preparation, targeting β-giardin (bg) and small subunit ribosomal RNA (ssu rRNA) gene, confirmed the presence of G. duodenalis (GenBank: OQ388331.1 , OQ388332.1 , OR029977.1 , OR029976.1 , OR029974.1 , OR029975.1 and PP316110.1 ) and E. histolytica (GenBank: OR016432.1 ). Antigens were prepared separately from these isolates, and the polyclonal antibodies (pAbs) were prepared in rabbits and purified using Protein-A-Sepharose affinity columns. Then, Anti‑Giardia IgG pAbs and Anti-Entamoeba IgG pAbs in-house sandwich ELISAs were tested separately on all fecal samples revealing infection rates of 45.2% (1208/2674) for Giardia sp. and 30.1% (805/2674) for Entamoeba sp. with high ability to detect Giardia (χ² = 281.2, p < 0.001) and Entamoeba (χ² = 125.6, p < 0.001) species compared to microscopy. In conclusion, the developed sandwich ELISA in our study represents a sensitive and reliable diagnostic tool for the detection of Giardia and Entamoeba infections in farm animals. Its application in routine surveillance along with complementary molecular confirmation could help to improve epidemiological accuracy and assess zoonotic risks.</p>","PeriodicalId":9041,"journal":{"name":"BMC Veterinary Research","volume":"22 1","pages":""},"PeriodicalIF":3.1,"publicationDate":"2026-08-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13476928/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148760861","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Some degrees of difference: impact of in vitro cultivation temperature on mesenchymal stromal cells from species with different body core temperatures.","authors":"Florian Pabst, Sabine Niebert, Susanna Schubert, Janina Burk","doi":"10.1186/s12917-026-05741-z","DOIUrl":"https://doi.org/10.1186/s12917-026-05741-z","url":null,"abstract":"<p><strong>Background: </strong>Multipotent mesenchymal stromal cells (MSC) are promising candidates for regenerative therapies in human and animal patients. However, limiting comparability between studies in different species, subtle differences between their MSC occur. Contributing to this, MSC culture protocols are mainly optimized for the human cells. For example, it remains widely neglected that the standard cultivation temperature at 37 °C does not match the body core temperature of several relevant animal species. Therefore, we here investigated growth and viability parameters of primary mesenchymal stromal cells from species with different body core temperatures, namely humans (37 °C) and sheep (38.5 °C), at different cultivation temperatures, including subphysiological, physiological and mild febrile temperatures for each species.</p><p><strong>Results: </strong>The cells showed the best proliferation characteristics and colony forming potential at the species' respective physiological body core temperature. Mild febrile temperatures altered cell morphologyand compromised colony forming unit potential (p < 0.05). Subphysiological temperatures had no significant effect on colony forming unit potential, but tended to slow proliferation with decreased metabolic activity of the cell cultures (p < 0.05 in human MSC). In addition, subphysiological temperatures increased apoptosis in human MSC (p < 0.05).</p><p><strong>Conclusions: </strong>Cultivation temperature impacts on mesenchymal stromal cell viability characteristics. The current study provides a first basis for species-specific temperature adaptation in MSC culture procedures, with relevance to translational animal studies, and possibly also to companion animal MSC treatments.</p>","PeriodicalId":9041,"journal":{"name":"BMC Veterinary Research","volume":"22 1","pages":""},"PeriodicalIF":3.1,"publicationDate":"2026-08-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13483555/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148787960","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effects of different levels of hemp seed meal supplementation in lamb diets on fattening performance and metabolic responses.","authors":"Başak Özten, Hacer Tüfekci, Hüseyin Çayan","doi":"10.1186/s12917-026-05807-y","DOIUrl":"10.1186/s12917-026-05807-y","url":null,"abstract":"<p><strong>Background: </strong>Hemp seed meal is being researched as an alternative feed material for ruminants. It is known that sheep perform well on a wide variety of alternative feeds due to their broad feeding preferences and ability to utilize feed sources that other animals cannot. This study aimed to evaluate the effects of adding hemp seed meal at different levels (5%, 10%, 15%) to lamb rations on fattening performance and certain blood characteristics. A total of 40 Akkaraman lambs, homogeneous in age and weight, were randomly divided into four groups (n = 10). The lambs, housed in individual pens, were fattened for 75 days after a two-week adaptation period. The lambs were fattened with four different rations: control ration, and rations supplemented with 5%, 10%, and 15% hemp seed meal (HSM).</p><p><strong>Results: </strong>In our study, there was no difference in the live weights of lambs fed the control or HSM-supplemented diets at different periods of the feeding period, or in their final live weights at the end of the feeding period, indicating that the overall performance of the animals was similar. Furthermore, there was no significant difference in feed conversion ratios between the groups. The biochemical characteristics in the blood serum of the lambs in this study indicate that HSM was well tolerated when supplemented to the ration and no side effects were seen during the fattening period.</p><p><strong>Conclusions: </strong>The results suggested that HSM can be added to lamb diets without causing adverse effects on lamb fattening performance or health.</p>","PeriodicalId":9041,"journal":{"name":"BMC Veterinary Research","volume":"22 1","pages":""},"PeriodicalIF":3.1,"publicationDate":"2026-08-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13621465/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149073474","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Taeniid infection in dogs: a coprological and knowledge, attitude and practices study in Gondar and Bahir Dar cities, Ethiopia.","authors":"Muluken Yayeh, Mastewal Birhan, Akililu Ayalew, Araya Menigstu","doi":"10.1186/s12917-026-05787-z","DOIUrl":"10.1186/s12917-026-05787-z","url":null,"abstract":"<p><strong>Background: </strong>The zoonotic cestodes such as Taenia and Echinococcus species belonging to family taeniidae are of paramount importance in the developing world since they pose serious public health impacts. Dogs serve as definitive hosts, shedding eggs into the environment that can infect livestock and humans.</p><p><strong>Aim: </strong>To determine the occurrence of Taeniid infections in dogs, assess the risk factors and evaluate the knowledge, attitudes, and practices (KAP) of dog owners.</p><p><strong>Methods: </strong>A cross-sectional study was conducted from September 2025 to February 2026 in Bahir Dar and Gondar cities, Ethiopia. A total of 424 dog fecal samples were collected, and standard fecal flotation techniques were used to examine the eggs. Structured questionnaires were used to gather information on host, management, and owner-related factors. Data were analyzed using chi-square tests and logistic regression in Stata 17, with P < 0.05 considered significant.</p><p><strong>Results: </strong>The overall prevalence of taeniid infections was 29.5%, with dogs showing clinical signs such as diarrhea and proglottids in the feces having the highest infection rates (81.1%). Chi-square analysis revealed significant associations with age, sex, clinical signs, roaming behavior, feeding patterns, and owner knowledge. Multivariate analysis confirmed that old age (AOR = 2.8, P = 0.024), female sex (AOR = 0.43, P = 0.007), clinical signs (AOR = 25.9, P = 0.001), free-roaming behavior (AOR = 0.05, P = 0.001), and inadequate owner knowledge (AOR = 0.38, P = 0.029) as independent risk factors.</p><p><strong>Conclusion: </strong>The study found that taeniid infections were common in dogs in Bahir Dar and Gondar. The main predictors were age, sex, clinical symptoms, free-roaming behavior, and a lack of owner knowledge. To lower the risk of taeniid infection in the study areas, integrated control measures like routine deworming; responsible dog management, public education, and appropriate offal disposal were suggested.</p>","PeriodicalId":9041,"journal":{"name":"BMC Veterinary Research","volume":"22 1","pages":""},"PeriodicalIF":3.1,"publicationDate":"2026-08-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13602561/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149036281","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Actinobacillus pleuropneumoniae - today's perspective on advances and challenges (2017- 2026).","authors":"Isabel Hennig-Pauka, Katrin Strutzberg-Minder, Paul R Langford","doi":"10.1186/s12917-026-05791-3","DOIUrl":"10.1186/s12917-026-05791-3","url":null,"abstract":"<p><p>Actinobacillus pleuropneumoniae (APP) remains one of the most significant bacterial respiratory pathogens in swine production worldwide, causing porcine pleuropneumonia with substantial economic impact. Although recent reviews have summarized aspects of APP epidemiology, serotyping, surface-associated virulence determinants, and vaccine development strategies, several complementary research areas have advanced rapidly since the last DISease CONtrol TOOLS (DISCONTOOLS) 2017 report on this bacterium. These include antimicrobial resistance surveillance, chronic persistence mechanisms such as biofilm formation, refined experimental infection models, intracellular survival within host immune cells, and the immunopathological processes driving lung injury. This review focuses on these practical and mechanistic dimensions, emphasizing their relevance for herd-level control, outbreak management, and future therapeutic approaches. Recent genomic studies of multidrug-resistant strains, as well as the development of improved molecular diagnostic tools, are also discussed. Collectively, emerging evidence suggests that APP should not be viewed solely as an extracellular pathogen causing acute disease outbreaks, but rather as an adaptable organism capable of persistence, immune modulation, and endemic circulation in modern pig populations. Addressing these challenges will require integrated strategies that combine antimicrobial stewardship, improved surveillance, and a deeper understanding of host-pathogen interactions.</p>","PeriodicalId":9041,"journal":{"name":"BMC Veterinary Research","volume":"22 1","pages":""},"PeriodicalIF":3.1,"publicationDate":"2026-08-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13465399/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148711350","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}