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Lost and found: dynamics of relationship and employment status over time in people with affective and psychotic spectrum disorders. 失而复得:情感和精神病谱系障碍患者的关系和就业状况随时间的动态变化。
IF 3.9 3区 医学
BJPsych Open Pub Date : 2024-12-26 DOI: 10.1192/bjo.2024.816
Fanny Senner, Lisa Kerkhoff, Kristina Adorjan, Michael Lauseker, Monika Budde, Maria Heilbronner, Janos L Kalman, Mojtaba Oraki Kohshour, Sergi Papiol, Daniela Reich-Erkelenz, Sabrina K Schaupp, Eva C Schulte, Thomas Vogl, Ion-George Anghelescu, Volker Arolt, Bernhardt T Baune, Udo Dannlowski, Nina Dalkner, Detlef E Dietrich, Andreas J Fallgatter, Christian Figge, Carsten Konrad, Fabian U Lang, Jens Reimer, Eva Z Reinighaus, Max Schmauß, Andrea Schmitt, Simon Senner, Carsten Spitzer, Jörg Zimmermann, Alkomiet Hasan, Peter Falkai, Thomas G Schulze, Urs Heilbronner, Sophie-Kathrin Greiner
{"title":"Lost and found: dynamics of relationship and employment status over time in people with affective and psychotic spectrum disorders.","authors":"Fanny Senner, Lisa Kerkhoff, Kristina Adorjan, Michael Lauseker, Monika Budde, Maria Heilbronner, Janos L Kalman, Mojtaba Oraki Kohshour, Sergi Papiol, Daniela Reich-Erkelenz, Sabrina K Schaupp, Eva C Schulte, Thomas Vogl, Ion-George Anghelescu, Volker Arolt, Bernhardt T Baune, Udo Dannlowski, Nina Dalkner, Detlef E Dietrich, Andreas J Fallgatter, Christian Figge, Carsten Konrad, Fabian U Lang, Jens Reimer, Eva Z Reinighaus, Max Schmauß, Andrea Schmitt, Simon Senner, Carsten Spitzer, Jörg Zimmermann, Alkomiet Hasan, Peter Falkai, Thomas G Schulze, Urs Heilbronner, Sophie-Kathrin Greiner","doi":"10.1192/bjo.2024.816","DOIUrl":"10.1192/bjo.2024.816","url":null,"abstract":"<p><strong>Background: </strong>Employment and relationship are crucial for social integration. However, individuals with major psychiatric disorders often face challenges in these domains.</p><p><strong>Aims: </strong>We investigated employment and relationship status changes among patients across the affective and psychotic spectrum - in comparison with healthy controls, examining whether diagnostic groups or functional levels influence these transitions.</p><p><strong>Method: </strong>The sample from the longitudinal multicentric PsyCourse Study comprised 1260 patients with affective and psychotic spectrum disorders and 441 controls (mean age ± s.d., 39.91 ± 12.65 years; 48.9% female). Multistate models (Markov) were used to analyse transitions in employment and relationship status, focusing on transition intensities. Analyses contained multiple multistate models adjusted for age, gender, job or partner, diagnostic group and Global Assessment of Functioning (GAF) in different combinations to analyse the impact of the covariates on the hazard ratio of changing employment or relationship status.</p><p><strong>Results: </strong>The clinical group had a higher hazard ratio of losing partner (hazard ratio 1.46, <i>P</i> < 0.001) and job (hazard ratio 4.18, <i>P</i> < 0.001) than the control group (corrected for age/gender). Compared with controls, clinical groups had a higher hazard of losing partner (affective group, hazard ratio 2.69, <i>P</i> = 0.003; psychotic group, hazard ratio 3.06, <i>P</i> = 0.001) and job (affective group, hazard ratio 3.43, <i>P</i> < 0.001; psychotic group, hazard ratio 4.11, <i>P</i> < 0.001). Adjusting for GAF, the hazard ratio of losing partner and job decreased in both clinical groups compared with controls.</p><p><strong>Conclusion: </strong>Patients face an increased hazard of job loss and relationship dissolution compared with healthy controls, and this is partially conditioned by the diagnosis and functional level. These findings underscore a high demand for destigmatisation and support for individuals in managing their functional limitations.</p>","PeriodicalId":9038,"journal":{"name":"BJPsych Open","volume":"11 1","pages":"e11"},"PeriodicalIF":3.9,"publicationDate":"2024-12-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11733486/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142891932","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Perinatal emotional skills groups for women and birthing people with borderline personality disorder: outcomes from a feasibility randomised controlled trial. 边缘型人格障碍妇女和产妇围产期情绪技能小组:可行性随机对照试验的结果。
IF 3.9 3区 医学
BJPsych Open Pub Date : 2024-12-26 DOI: 10.1192/bjo.2024.833
Paul Moran, Debra Bick, Lucy Biddle, Belinda Borries, Rebecca Kandiyali, Farah Mgaieth, Vivan Patel, Janice Rigby, Penny Seume, Vaneeta Sadhnani, Nadine Smith, Michaela Swales, Nicholas Turner
{"title":"Perinatal emotional skills groups for women and birthing people with borderline personality disorder: outcomes from a feasibility randomised controlled trial.","authors":"Paul Moran, Debra Bick, Lucy Biddle, Belinda Borries, Rebecca Kandiyali, Farah Mgaieth, Vivan Patel, Janice Rigby, Penny Seume, Vaneeta Sadhnani, Nadine Smith, Michaela Swales, Nicholas Turner","doi":"10.1192/bjo.2024.833","DOIUrl":"10.1192/bjo.2024.833","url":null,"abstract":"<p><strong>Background: </strong>There is no clear evidence about how to support people with borderline personality disorder (BPD) during the perinatal period. Perinatal emotional skills groups (ESGs) may be helpful, but their efficacy has not been tested.</p><p><strong>Aims: </strong>To test the feasibility of conducting a randomised controlled trial (RCT) of perinatal ESGs for women and birthing people with BPD.</p><p><strong>Method: </strong>Two-arm parallel-group feasibility RCT. We recruited people from two centres, aged over 18 years, meeting DSM-5 diagnostic criteria for BPD, who were pregnant or within 12 months of a live birth. Eligible individuals were randomly allocated on a 1:1 ratio to ESGs + treatment as usual (TAU), or to TAU. Outcomes were assessed at 4 months post randomisation.</p><p><strong>Results: </strong>A total of 100% of the pre-specified sample (<i>n</i> = 48) was recruited over 6 months, and we obtained 4-month outcome data on 92% of randomised participants. In all, 54% of participants allocated to perinatal ESGs attended 75% of the full group treatment (median number of sessions: 9 (interquartile range 6-11). At 4 months, levels of BPD symptoms (adjusted coefficient -2.0, 95% CI -6.2 to 2.1) and emotional distress (-2.4, 95% CI -6.2 to 1.5) were lower among those allocated to perinatal ESGs. The directionality of effect on well-being and social functioning also favoured the intervention. The cost of delivering perinatal ESGs was estimated to be £918 per person.</p><p><strong>Conclusions: </strong>Perinatal ESGs may represent an effective intervention for perinatal women and birthing people with BPD. Their efficacy should be tested in a fully powered RCT, and this is a feasible undertaking.</p><p><strong>Trial registration: </strong>ISRCTN80470632.</p>","PeriodicalId":9038,"journal":{"name":"BJPsych Open","volume":"11 1","pages":"e12"},"PeriodicalIF":3.9,"publicationDate":"2024-12-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11733485/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142891935","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Effect of improving food security on parenting practices and caregiver-adolescent relationships: qualitative findings of an income-generating agricultural intervention in rural Kenya. 改善粮食安全对养育实践和照顾者与青少年关系的影响:肯尼亚农村创收农业干预的定性研究结果。
IF 3.9 3区 医学
BJPsych Open Pub Date : 2024-12-26 DOI: 10.1192/bjo.2024.802
Maricianah A Onono, Lila Sheira, Edward A Frongilio, Gladys Odhiambo, Pauline Wekesa, Amy Conroy, Elizabeth A Bukusi, Craig R Cohen, Sheri D Weiser
{"title":"Effect of improving food security on parenting practices and caregiver-adolescent relationships: qualitative findings of an income-generating agricultural intervention in rural Kenya.","authors":"Maricianah A Onono, Lila Sheira, Edward A Frongilio, Gladys Odhiambo, Pauline Wekesa, Amy Conroy, Elizabeth A Bukusi, Craig R Cohen, Sheri D Weiser","doi":"10.1192/bjo.2024.802","DOIUrl":"10.1192/bjo.2024.802","url":null,"abstract":"<p><strong>Background: </strong>Despite the recognised links between food insecurity and parenting, few studies have evaluated the perceived impacts of livelihood or food security interventions on parental practices, intra-household functioning, adolescent behaviour and psychosocial outcomes in HIV-affected households in sub-Saharan Africa.</p><p><strong>Aims: </strong>The study aimed to understand the perceived effects of food security on parenting practices and how this was experienced by both adolescent girls (aged 13-19 years) and their caregivers in rural Kenya.</p><p><strong>Method: </strong>We conducted semi-structured, individual interviews with 62 caregiver-adolescent dyads who were participants in the adolescent <i>Shamba Maisha</i> (NCT03741634), a sub-study of adolescent girls and caregivers with a household member participating in the <i>Shamba Maisha</i> agricultural and finance intervention trial (NCT01548599). Data were analysed following the principles of thematic analysis.</p><p><strong>Results: </strong>Compared to control households, the <i>Shamba Maisha</i> intervention households had improved food security and strengthened economic security, which, in turn, improved parenting practices. Intervention households described changes in parenting experiences, including decreased parental stress, reduced absenteeism and harsh parenting and improved caregiver- adolescent relationships. These positive caregiving practices, in turn, contributed to improved mental health and fewer behavioural problems among adolescent girls. Changes in the control households were less noticeable.</p><p><strong>Conclusion: </strong>These findings demonstrate how an income-generating agricultural intervention may improve food security and positively affect parenting practices, intra-household dynamics and adolescent psychosocial well-being and behaviour. Further research is needed to explore how to harness the social benefits of agricultural interventions to best address the critical intersections among food insecurity, parenting practices and adolescent mental health.</p>","PeriodicalId":9038,"journal":{"name":"BJPsych Open","volume":"11 1","pages":"e10"},"PeriodicalIF":3.9,"publicationDate":"2024-12-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11733493/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142891930","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Indigenous-non-Indigenous disparities in health and social outcomes 5 years after first episode psychosis: national cohort study. 精神病首次发作 5 年后,原住民与非原住民在健康和社会结果方面的差异:全国队列研究。
IF 3.9 3区 医学
BJPsych Open Pub Date : 2024-12-20 DOI: 10.1192/bjo.2024.827
Ruth Cunningham, Frederieke Petrović-van der Deen, Sheree Gibb, Marie Crowe, Jenni Manuel, Suzanne Pitama, Sue Crengle, Richard Porter, Cameron Lacey
{"title":"Indigenous-non-Indigenous disparities in health and social outcomes 5 years after first episode psychosis: national cohort study.","authors":"Ruth Cunningham, Frederieke Petrović-van der Deen, Sheree Gibb, Marie Crowe, Jenni Manuel, Suzanne Pitama, Sue Crengle, Richard Porter, Cameron Lacey","doi":"10.1192/bjo.2024.827","DOIUrl":"10.1192/bjo.2024.827","url":null,"abstract":"<p><strong>Background: </strong>There are ethnic differences, including differences related to indigeneity, in the incidence of first episode psychosis (FEP) and pathways into care, but research on ethnic disparities in outcomes following FEP is limited.</p><p><strong>Aims: </strong>In this study we examined social and health outcomes following FEP diagnosis for a cohort of Māori (Indigenous people of New Zealand) and non-Māori (non-Indigenous) young people. We have focused on understanding the opportunities for better outcomes for Māori by examining the relative advantage of non-Māori with FEP.</p><p><strong>Method: </strong>Statistics New Zealand's Integrated Data Infrastructure was accessed to describe mental health and social service interactions and outcomes for a retrospective FEP cohort comprising 918 young Māori and 1275 non-Māori aged 13 to 25 at diagnosis. Logistic regression models were used to examine whether social outcomes including employment, benefit receipt, education and justice involvement in year 5 differed by indigeneity.</p><p><strong>Results: </strong>Non-Māori young people were more likely than Māori to have positive outcomes in the fifth year after FEP diagnosis, including higher levels of employment and income, and lower rates of benefit receipt and criminal justice system involvement. These patterns were seen across diagnostic groups, and for both those receiving ongoing mental healthcare and those who were not.</p><p><strong>Conclusions: </strong>Non-Māori experience relative advantage in outcomes 5 years after FEP diagnosis. Indigenous-based social disparities following FEP urgently require a response from the health, education, employment, justice and political systems to avoid perpetuating these inequities, alongside efforts to address the disadvantages faced by all young people with FEP.</p>","PeriodicalId":9038,"journal":{"name":"BJPsych Open","volume":"11 1","pages":"e9"},"PeriodicalIF":3.9,"publicationDate":"2024-12-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11733454/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142863033","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The SLaM Brain Health Clinic: remote biomarker enhanced memory clinic for people with mild cognitive impairment within a National Health Service mental health trust. SLaM脑健康诊所:远程生物标志物增强记忆诊所轻度认知障碍的人在国民健康服务精神健康信托。
IF 3.9 3区 医学
BJPsych Open Pub Date : 2024-12-19 DOI: 10.1192/bjo.2024.829
Ashwin V Venkataraman, Pooja Kandangwa, Roos Lemmen, Rutvi Savla, Mazda Beigi, Devon Hammond, Daniel Harwood, Justin Sauer, Latha Velayudhan, Clive Ballard, Anna-Katharine Brem, Chris Kalafatis, Dag Aarsland
{"title":"The SLaM Brain Health Clinic: remote biomarker enhanced memory clinic for people with mild cognitive impairment within a National Health Service mental health trust.","authors":"Ashwin V Venkataraman, Pooja Kandangwa, Roos Lemmen, Rutvi Savla, Mazda Beigi, Devon Hammond, Daniel Harwood, Justin Sauer, Latha Velayudhan, Clive Ballard, Anna-Katharine Brem, Chris Kalafatis, Dag Aarsland","doi":"10.1192/bjo.2024.829","DOIUrl":"10.1192/bjo.2024.829","url":null,"abstract":"<p><strong>Background: </strong>The novel South London and Maudsley Brain Health Clinic (SLaM BHC) leverages advances in remote consultations and biomarkers to provide a timely, cost-efficient and accurate diagnosis in mild cognitive impairment (MCI).</p><p><strong>Aims: </strong>To describe the organisation, patient cohort and acceptability of the remote diagnostic and interventional procedures.</p><p><strong>Method: </strong>We describe the recruitment, consultation set-up, the clinical and biomarker programme, and the two online group interventions for cognitive wellbeing and lifestyle change. We evaluate the acceptability of the remote consultations, lumbar puncture, saliva genotyping, and remote cognitive and functional assessments.</p><p><strong>Results: </strong>We present the results of the first 68 (mean age 73, 55% female, 43% minoritised ethnicity) of 146 people who enrolled for full remote clinical, cognitive, genetic, cerebrospinal fluid and neuroimaging phenotyping. A total of 86% were very satisfied/satisfied with the remote service. In all, 67% consented to lumbar puncture, and 95% of those were very satisfied, all having no significant complications. A total of 93% found taking saliva genotyping very easy/easy, and 93% found the cognitive assessments instructions clear. In all, 98% were satisfied with the Cognitive Wellbeing Group, and 90% of goals were achieved in the Lifestyle Intervention Group.</p><p><strong>Conclusions: </strong>The SLaM BHC provides a highly acceptable and safe clinical model for remote assessments and lumbar punctures in a representative, ethnically diverse population. This allows early and accurate diagnosis of Alzheimer's disease, differentiation from other MCI causes and targets modifiable risk factors. This is crucial for future disease modification, ensuring equitable access to research, and provides precise, timely and cost-efficient diagnoses in UK mental health services.</p>","PeriodicalId":9038,"journal":{"name":"BJPsych Open","volume":"11 1","pages":"e8"},"PeriodicalIF":3.9,"publicationDate":"2024-12-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11733455/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142852425","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Evidence for music therapy and music medicine in psychiatry: transdiagnostic meta-review of meta-analyses. 精神病学中音乐治疗和音乐医学的证据:对荟萃分析的跨诊断荟萃回顾。
IF 3.9 3区 医学
BJPsych Open Pub Date : 2024-12-13 DOI: 10.1192/bjo.2024.826
Alexander Lassner, Spyridon Siafis, Emanuel Wiese, Stefan Leucht, Susanne Metzner, Elias Wagner, Alkomiet Hasan
{"title":"Evidence for music therapy and music medicine in psychiatry: transdiagnostic meta-review of meta-analyses.","authors":"Alexander Lassner, Spyridon Siafis, Emanuel Wiese, Stefan Leucht, Susanne Metzner, Elias Wagner, Alkomiet Hasan","doi":"10.1192/bjo.2024.826","DOIUrl":"10.1192/bjo.2024.826","url":null,"abstract":"<p><strong>Background: </strong>Music therapy is a commonly used intervention added to usual care for psychiatric disorders.</p><p><strong>Aims: </strong>We review the evidence for music therapy and assess its efficacy as an adjunct therapy across psychiatric disorders.</p><p><strong>Method: </strong>A systematic literature search was conducted in four scientific databases to identify relevant meta-analyses. Articles were assessed with the AMSTAR-2 tool. The results of the high-quality articles were recalculated with the data from the primary studies. We decided to add the results of the lower-rated articles, using a narrative approach. We pooled the primary studies and calculated standardised mean differences (SMD) for the transdiagnostic outcomes of depression, anxiety and quality of life. We used the Grading of Recommendations, Assessment, Development and Evaluations (GRADE) tool to assess the level of evidence.</p><p><strong>Results: </strong>Meta-analyses were available for autism, dementia, depression, insomnia, schizophrenia and substance use disorders. We identified 40 relevant articles. One article per domain was identified as high quality. Music therapy added to treatment as usual showed therapeutic value in each disorder. The transdiagnostic results showed a positive effect of music therapy on depression (SMD = 0.57, 95% CI 0.36-0.78), anxiety (SMD = 0.47, 95% CI 0.27-0.66) and quality of life (SMD = 0.47, 95% CI 0.24-0.71). However, these effects were not maintained at follow-up, and all results were based on low or very low evidence.</p><p><strong>Conclusions: </strong>Music therapy shows promising potential as an adjunctive treatment for psychiatric disorders, but methodological weaknesses and variability limit the evidence. More high-quality, well-powered studies are needed to reliably confirm its effect size.</p>","PeriodicalId":9038,"journal":{"name":"BJPsych Open","volume":"11 1","pages":"e4"},"PeriodicalIF":3.9,"publicationDate":"2024-12-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11733488/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142817153","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Prevalence of probable post-traumatic stress disorder and experiences of trauma in emerging adults living with HIV in Zimbabwe. 津巴布韦新近感染艾滋病毒的成年人中可能存在的创伤后应激障碍和创伤经历。
IF 3.9 3区 医学
BJPsych Open Pub Date : 2024-12-13 DOI: 10.1192/bjo.2024.720
Renato Silveira, Sainath Eleti, Emily Saruchera, Rukudzo Mwamuka, Susannah Whitwell, Melanie A Abas, Helen E Jack
{"title":"Prevalence of probable post-traumatic stress disorder and experiences of trauma in emerging adults living with HIV in Zimbabwe.","authors":"Renato Silveira, Sainath Eleti, Emily Saruchera, Rukudzo Mwamuka, Susannah Whitwell, Melanie A Abas, Helen E Jack","doi":"10.1192/bjo.2024.720","DOIUrl":"10.1192/bjo.2024.720","url":null,"abstract":"<p><strong>Background: </strong>Little is known about the prevalence of post-traumatic stress disorder (PTSD) in emerging adults living with HIV in low-income countries.</p><p><strong>Aims: </strong>Determine prevalence of trauma exposure, prevalence of probable PTSD and conditional prevalence of probable PTSD for different traumatic events; and better understand the experiences of individuals with HIV and PTSD.</p><p><strong>Method: </strong>This mixed method study used secondary data from a cross-sectional survey of people (<i>N</i> = 222) aged 18 to 29 living with HIV in Zimbabwe and primary qualitative data collection. The PTSD Checklist for DSM-5 (PCL-5) and the Life Events Checklist for DSM-5 (LEC-5) were used to measure PTSD and exposure to traumatic events, both translated to Shona. In-depth interviews (<i>n</i> = 8) with participants who met the criteria for probable PTSD were analysed using thematic analysis.</p><p><strong>Results: </strong>In all, 68.3% [95% CI (61.4-74.1)] of participants reported exposure to at least one traumatic event. The observed prevalence of probable PTSD was 8.6% [95% CI (5.2-13.0)], most observed following exposure to fire or explosion 29.0% [95% CI (13.0-45.0)] and sexual assault 27.8% [95% CI (7.2-48.7)]. Probable PTSD was also more prevalent following multiple exposure to trauma; four and six events, <i>N</i> = 4 (21%) [95% CI (5.1-8.8)] each, two and three events <i>N</i> = 3 (15.7%) [95% CI (5.9-9.2)] each, and five events <i>N</i> = 1 (5.4%) [95% CI (7.5-9.6)]. Qualitative results indicated that HIV stigma exacerbated psychological distress from trauma.</p><p><strong>Conclusions: </strong>Despite trauma exposure being common, prevalence of probable PTSD was not high, but was higher in those with multiple exposures. Participants described coping strategies, including social support and religious thinking.</p>","PeriodicalId":9038,"journal":{"name":"BJPsych Open","volume":"11 1","pages":"e7"},"PeriodicalIF":3.9,"publicationDate":"2024-12-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11733456/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142817183","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Psychotic disorders in HIV-positive versus HIV-negative patients: comparative study of clinical characteristics. hiv阳性与hiv阴性患者的精神障碍:临床特征的比较研究
IF 3.9 3区 医学
BJPsych Open Pub Date : 2024-12-13 DOI: 10.1192/bjo.2024.771
Noeline Nakasujja, Seggane Musisi, Hans Agren, Elly Katabira, Peter Allebeck
{"title":"Psychotic disorders in HIV-positive versus HIV-negative patients: comparative study of clinical characteristics.","authors":"Noeline Nakasujja, Seggane Musisi, Hans Agren, Elly Katabira, Peter Allebeck","doi":"10.1192/bjo.2024.771","DOIUrl":"10.1192/bjo.2024.771","url":null,"abstract":"<p><strong>Background: </strong>Clinical characteristics of psychosis in HIV infection have been described, but there have been limited comparative studies in HIV-endemic low-resource regions.</p><p><strong>Aim: </strong>To compare clinical characteristics of psychosis in HIV-positive and HIV-negative patients at the main psychiatric referral units in Uganda.</p><p><strong>Method: </strong>Patients with psychosis were consecutively recruited and completed a standardised demographic questionnaire and psychiatric and laboratory assessments including an HIV test. The Mini International Neuropsychiatric Interview was used to diagnose psychiatric illness. Psychosis symptoms were compared between HIV-positive and HIV-negative individuals using bivariate methods. A logistic regression model was used to assess the effects of age, gender and HIV status on different types of psychosis.</p><p><strong>Results: </strong>There were 478 patients enrolled, of which 156 were HIV positive and 322 were HIV negative. The mean age was 33.2 years (95% CI 31.8-34.5) for the HIV-positive group and 29.6 years (95% CI 28.7-30.5) for the HIV-negative group (<i>P</i> < 0.001). Female patients had a higher proportion of seropositivity 40.6% (95% CI 34.8-46.4) compared with males 21.8% (95% CI 16.1-27.5) (<i>P</i> < 0.001). Psychotic disorder not otherwise specified occurred more in the HIV-positive individuals (88% (95% CI 82.9-93.1) <i>v.</i> 12% (95% CI 8.4-15.5), <i>P</i> < 0.001). Motor activity, irritability, emotional withdrawal, feelings of guilt, mannerisms and posturing, grandiosity, suspiciousness, unusual thoughts, blunted affect, excitement and disorientation were associated with HIV seropositivity.</p><p><strong>Conclusion: </strong>The presentation of psychosis in patients with HIV is unique to this HIV endemic setting. Characterisation of the symptomatology of patients presenting with psychosis is important for proper diagnosis and care.</p>","PeriodicalId":9038,"journal":{"name":"BJPsych Open","volume":"11 1","pages":"e2"},"PeriodicalIF":3.9,"publicationDate":"2024-12-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11733458/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142817186","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Subcutaneous electroencephalography monitoring for people with epilepsy and intellectual disability: co-production workshops. 癫痫和智力残疾者的皮下脑电图监测:联合制作讲习班。
IF 3.9 3区 医学
BJPsych Open Pub Date : 2024-12-13 DOI: 10.1192/bjo.2024.825
Edward Meinert, Madison Milne-Ives, Jennifer Sawyer, Liz Boardman, Sarah Mitchell, Brendan Mclean, Mark Richardson, Rohit Shankar
{"title":"Subcutaneous electroencephalography monitoring for people with epilepsy and intellectual disability: co-production workshops.","authors":"Edward Meinert, Madison Milne-Ives, Jennifer Sawyer, Liz Boardman, Sarah Mitchell, Brendan Mclean, Mark Richardson, Rohit Shankar","doi":"10.1192/bjo.2024.825","DOIUrl":"10.1192/bjo.2024.825","url":null,"abstract":"<p><strong>Background: </strong>Nearly 25% of people with intellectual disability (PwID) have epilepsy compared to 1% of the UK general population. PwID are commonly excluded from research, eventually affecting their care. Understanding seizures in PwID is particularly challenging because of reliance on subjective external observation and poor objective validation. Remote electroencephalography (EEG) monitoring could capture objective data, but particular challenges and implementation strategies for this population need to be understood.</p><p><strong>Aim: </strong>This co-production aimed to explore the accessibility and potential impact of a remote, long-term EEG tool (UnEEG 24/7 SubQ) for PwID and epilepsy.</p><p><strong>Method: </strong>We conducted six, 2-hour long workshops; three with people with mild intellectual disability and three with families/carers of people with moderate-profound intellectual disability. Brief presentations, easy read information and model demonstrations were used to explain the problem and device. A semi-structured guide developed by a communication specialist and art-based techniques facilitated discussion with PwID. For family/carers, active listening was employed. All conversations were recorded and transcribed. Artificial intelligence-based coding and thematic analysis (ATLAS.ti and ChatGPT) were synthesised with manual theming to generate insights.</p><p><strong>Results: </strong>Co-production included four PwID, five family members and seven care professionals. Three main themes were identified: (1) perceived benefits for improving seizure understanding, informing care and reducing family and carer responsibility to accurately identify seizures; (2) the device was feasible for some PwID but not all; and (3) appropriate person-centred communication is essential for all stakeholders to reduce concerns.</p><p><strong>Conclusions: </strong>The workshops identified key benefits and implementing barriers to SubQ in PwID.</p>","PeriodicalId":9038,"journal":{"name":"BJPsych Open","volume":"11 1","pages":"e3"},"PeriodicalIF":3.9,"publicationDate":"2024-12-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11733491/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142817231","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Factor validation of the International Trauma Questionnaire in a sample of trauma-exposed Colombian adults in the MI-VIDA study. MI-VIDA研究中创伤暴露的哥伦比亚成人样本中国际创伤问卷的因素验证
IF 3.9 3区 医学
BJPsych Open Pub Date : 2024-12-13 DOI: 10.1192/bjo.2024.752
Martin Robinson, Donncha Hanna, Natasha Bloch, Chérie Armour
{"title":"Factor validation of the International Trauma Questionnaire in a sample of trauma-exposed Colombian adults in the MI-VIDA study.","authors":"Martin Robinson, Donncha Hanna, Natasha Bloch, Chérie Armour","doi":"10.1192/bjo.2024.752","DOIUrl":"10.1192/bjo.2024.752","url":null,"abstract":"<p><strong>Background: </strong>The ICD-11 introduced a new diagnosis of complex post-traumatic stress disorder (CPTSD) defined by disturbances in self-organisation in addition to traditional post-traumatic stress disorder symptoms. The International Trauma Questionnaire (ITQ) is the established measure of this construct and has been validated for use in a variety of populations and languages; however, evidence for the measure's use in Latin America is limited.</p><p><strong>Aims: </strong>This study sought to validate the factor structure of the Latin American Spanish version of the ITQ in a trauma-exposed sample in Colombia.</p><p><strong>Method: </strong>Confirmatory factor analysis was used to assess a range of factor models validated previously, including first- and second-order factor models.</p><p><strong>Results: </strong>Assessment of fit indices demonstrated that a correlated six-factor model comprised of re-experiencing, avoidance, sense of threat, affect dysregulation, negative self-concept and disturbed relationships provided the best fit for these data. Factor loadings for this model were found to be high and statistically significant.</p><p><strong>Conclusion: </strong>Results concur with prior research validating the use of alternative language versions of the ITQ internationally, and with the theoretical underpinnings of the CPTSD diagnostic category. The ITQ is therefore a valid measure of CPTSD in this Latin American sample. Further validation research is needed in clinical populations in this region.</p>","PeriodicalId":9038,"journal":{"name":"BJPsych Open","volume":"11 1","pages":"e6"},"PeriodicalIF":3.9,"publicationDate":"2024-12-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11740317/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142817156","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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