BJPsych Open最新文献

{"title":"Beliefs about the causes and treatment of common mental illnesses and suicidality in rural Uganda.","authors":"Yang Jae Lee, Rita Mbabazi, Ondine Jevremov, Shakira Nakaweesi, Ella Brodey, Jason Wykoff, Roshan Sivakumar, Rauben Kazungu, Ibrahim Ssekalo, Robert Rosenheck, Alexander C Tsai","doi":"10.1192/bjo.2025.10066","DOIUrl":"10.1192/bjo.2025.10066","url":null,"abstract":"<p><strong>Background: </strong>Mental illnesses constitute a large and escalating portion of the global burden of disease, particularly in low- and middle-income countries like Uganda. Understanding community perceptions towards mental illness is crucial for developing effective interventions.</p><p><strong>Aims: </strong>To explore beliefs about the perceived causes and treatment of common mental illnesses (depression, anxiety, alcohol use disorder) and suicidality in rural eastern Uganda.</p><p><strong>Method: </strong>Qualitative study using 31 in-depth interviews and 4 focus group discussions with healthcare workers, community health workers, community leaders and general community members in Buyende District, Uganda. Vignettes were used to depict mental illnesses to elicit perceptions, and data were analysed using the framework method.</p><p><strong>Results: </strong>Two main themes emerged: perceived causes and treatment of mental illness. Participants identified three primary perceived causes: psychosocial (predominantly financial stress), biological and supernatural. Community support was most frequently endorsed as a perceived effective treatment, followed by biomedical interventions and alternative therapies.</p><p><strong>Conclusions: </strong>This study identifies common beliefs regarding the causes and perceptions of mental illness in rural Uganda. The predominant focus on financial stressors as a cause of mental illness, coupled with strong emphasis and belief in the effectiveness of community-based support as treatment, highlights the need for context-specific mental health interventions.</p>","PeriodicalId":9038,"journal":{"name":"BJPsych Open","volume":"11 4","pages":"e146"},"PeriodicalIF":3.9,"publicationDate":"2025-07-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12247074/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144582998","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The impact of COVID-19 on parents from Black ethnic backgrounds in the UK: what we have learned and why it still matters.","authors":"Valentina Cardi, Valentina Meregalli, Chiara Tosi, Laura Sudulich, Juliana Onwumere","doi":"10.1192/bjo.2025.10049","DOIUrl":"10.1192/bjo.2025.10049","url":null,"abstract":"<p><strong>Background: </strong>People from ethnic minority groups are more likely to be impacted by global disasters than White ethnic groups due to pre-existing vulnerabilities. A lack of trust in mainstream support services, which have often accounted poorly for the needs of those communities, contributes to further discrimination and disadvantage.</p><p><strong>Aims: </strong>This study was conducted in 2022, soon after the COVID-19 pandemic, to survey the overall well-being and healthcare needs of UK families with a Black ethnic background.</p><p><strong>Method: </strong>A total of 2124 parents completed an online survey that included measures of psychological well-being, children's difficulties, family healthcare needs and perception of support both before and after the COVID-19 pandemic.</p><p><strong>Results: </strong>Seventy per cent of parents reported high levels of stress, depression and anxiety, and over half identified high emotional and relational difficulties in their children. Higher levels of distress in parents correlated with greater difficulties in children and poorer parent-child relationships. Community support was associated with greater parental well-being and fewer child difficulties. Parents sought support from formal support networks when health issues were perceived as more severe.</p><p><strong>Conclusions: </strong>This study engaged a large sample of families from Black ethnic backgrounds, but recruitment may have been biased by sociodemographic characteristics. Levels of psychological distress were high, possibly due to pre-existing and enduring exposure to difficult life circumstances. Support from community networks was perceived as helpful, especially by those with milder levels of psychological distress. The strong association between parents' and children's well-being suggests that family-focused interventions could be beneficial, especially if culturally adapted.</p>","PeriodicalId":9038,"journal":{"name":"BJPsych Open","volume":"11 4","pages":"e143"},"PeriodicalIF":3.9,"publicationDate":"2025-07-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12247070/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144583010","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Bidirectional relationships between cognition and depressive symptoms and effects of sociodemographic and lifestyle factors: random-intercept, cross-lagged panel model.","authors":"Ted C T Fong, Ryder T H Chan, Ming Wen, Paul S F Yip","doi":"10.1192/bjo.2025.10074","DOIUrl":"10.1192/bjo.2025.10074","url":null,"abstract":"<p><strong>Background: </strong>Existing panel studies on the relationships between cognition and depressive symptoms did not systematically separate between- and within-person components, with measurement time lags that are too long for precise assessment of dynamic within-person relationships.</p><p><strong>Aims: </strong>To investigate the bidirectional relationships between cognition and depressive symptoms and examine the effects of sociodemographic characteristics and lifestyle factors via random-intercept, cross-lagged panel modelling (RI-CLPM) in middle-aged and older adults.</p><p><strong>Method: </strong>The sample comprised 24 425 community-based residents aged 45 years or above, recruited via five waves of the China Health and Retirement Longitudinal Study (2011-2020). Cognition was evaluated using the Telephone Interview of Cognition Status, and depressive symptoms were assessed by the ten-item Center for Epidemiologic Studies Depression Scale. RI-CLPM included sociodemographic and lifestyle factors as time-invariant and -varying covariates. Subgroup analysis was conducted across gender, age groups and urban/rural regions.</p><p><strong>Results: </strong>RI-CLPM showed a superior fit to cross-lagged panel models. Male, higher education, married, urban region, non-smoking, currently working and participation in social activities were linked with better cognition and fewer depressive symptoms. Overall, cognition and depressive symptoms showed significant and negative bidirectional cross-lagged effects over time. Despite similar cross-lagged effects across gender, subgroup analysis across urbanicity found that cross-lagged effects were not significant in urban regions.</p><p><strong>Conclusions: </strong>The present study provided nuanced results on negative bidirectional relationships between cognition and depressive symptoms in Chinese middle-aged and older adults. Our results highlight the health disparities in cognitive and emotional health across urbanicity and age groups.</p>","PeriodicalId":9038,"journal":{"name":"BJPsych Open","volume":"11 4","pages":"e144"},"PeriodicalIF":3.9,"publicationDate":"2025-07-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12247057/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144583008","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Recovery, completion and further referral after Improving Access to Psychological Therapies in Norfolk and Waveney.","authors":"Amanda Burke, Max Bachmann, Charlotte E L Jones, Julii Brainard, Zillur Rahman Shabuz, Alice M Dalton, Rachel Cullum, Nick Steel","doi":"10.1192/bjo.2025.10045","DOIUrl":"10.1192/bjo.2025.10045","url":null,"abstract":"<p><strong>Background: </strong>Improving Access to Psychological Therapies (IAPT), an NHS England service providing talking therapies, is meeting its target recovery rate of 50%. However, engagement in treatment, as well as recovery rates, may be lower for some groups.</p><p><strong>Aims: </strong>To assess variation in treatment completion and recovery rates by demographic and socioeconomic group and to describe rates of further referrals for patients to IAPT and secondary mental health services.</p><p><strong>Method: </strong>Using 121 548 administrative records for 2019-2020 and 2022-2023 for the Norfolk and Waveney area, we estimated associations of age, gender, ethnicity and deprivation with the likelihood of treatment completion and recovery using logistic regression modelling. We also described rates of further referrals.</p><p><strong>Results: </strong>Younger people and those living in deprived areas were less likely to recover or complete treatment, with those aged 16-17 years (<i>n</i> = 735) having the lowest adjusted odds for recovery (adjusted odds ratio = 0.5, 95% CI: 0.5-0.6) compared with those aged 36-70 years, and those aged 18-24 years (<i>n</i> = 23 563) having the lowest rate of completion (adjusted odds ratio = 0.5, 95% CI: 0.5-0.6). Further referrals before April 2022 were recorded for 45.4% of 6513 patients who had completed treatment and 68.8% of 9469 who had not completed treatment, and for 39.4% of 2007 recovered patients in 2019-2020 and 53.1% of 1586 who had not recovered. Non-completers had relatively more further referrals to secondary mental health services compared with completers (43.6% <i>v</i>. 22.8%; <i>P</i> < 0.01).</p><p><strong>Conclusions: </strong>Younger people and those living in deprived areas have lower recovery and completion rates. Those who have completed treatment and not recovered have higher rates of further referrals.</p>","PeriodicalId":9038,"journal":{"name":"BJPsych Open","volume":"11 4","pages":"e140"},"PeriodicalIF":3.9,"publicationDate":"2025-07-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12247062/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144574792","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Let's Talk About Voices: randomised controlled crossover study of a resource to support mental health workers in supporting voice-hearers.","authors":"Anne Honey, Justin Newton Scanlan, Lyndal Sherwin, Haylee Zink, Karen Wells, Glenda Jessup, Nicola Hancock","doi":"10.1192/bjo.2025.10071","DOIUrl":"10.1192/bjo.2025.10071","url":null,"abstract":"<p><strong>Background: </strong>Easily accessible, impactful, evidence-based resources are needed to assist mental health workers to best support voice-hearers in managing and living well with voices. Let's Talk About Voices (LTAV) is an innovative suite of resources designed for mental health workers to use in supporting voice-hearers.</p><p><strong>Aim: </strong>This study aimed to assess the impact of LTAV on mental health workers' self-reported capacity to work with voice-hearers.</p><p><strong>Method: </strong>A randomised, controlled crossover design was used, with assessment at three time points. The assessment measure was co-developed by researchers, clinicians, peer workers and voice-hearers based on the aims of LTAV and the Theory of Planned Behaviour. Participants were randomised into two groups. The immediate group received access to LTAV following the first assessment; the delayed group received access following the second assessment. In total, 256 mental health workers commenced the study, with 120 completing all assessments.</p><p><strong>Results: </strong>Between-group comparisons for change between times 1 and 2 found a significant difference with a large effect size (<i>F</i> = 40.2, <i>P</i> < 0.001, <i>η_p</i>² = 0.19). Significance remained on intention-to-treat analysis (<i>F</i> = 22.9, <i>P</i> < 0.001, <i>η_p</i>² = 0.08). Pairwise repeated-measures comparisons found a significant increase in scores for both groups following access to LTAV, which was sustained at follow-up. Fourteen of 24 individual items showed significant change. Changes were consistent across professions, work settings and experience working with voice-hearers, but those with less confidence in working with voice-hearers on intake showed significantly stronger improvements.</p><p><strong>Conclusions: </strong>This research indicates that LTAV has the potential to substantially improve mental health workers' attitudes and confidence in supporting voice-hearers.</p>","PeriodicalId":9038,"journal":{"name":"BJPsych Open","volume":"11 4","pages":"e139"},"PeriodicalIF":3.9,"publicationDate":"2025-07-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12247076/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144574791","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Bidirectional associations among positive affect, anhedonia and meaning in life during major depressive episode: ecological momentary assessment study in unipolar and bipolar individuals and healthy controls.","authors":"Heidi Ka Ying Lo, Roger S McIntyre, Iris Wai Tung Tsui, Fiona Yan Yee Ho, Ting Kin Ng, Corine Sau Man Wong, Suet Ying Yuen, Chit Tat Lee, Chun Yin Poon, Inez Myin-Germeys, Ka Fai Chung","doi":"10.1192/bjo.2025.10067","DOIUrl":"10.1192/bjo.2025.10067","url":null,"abstract":"<p><strong>Background: </strong>Diagnostic accuracy is an unmet need for major depressive disorder (MDD) and major depressive episode (MDE) in bipolar disorder. Very limited research has evaluated bipolar disorder/MDE and MDD using ecological momentary assessment (EMA) time-series data.</p><p><strong>Aims: </strong>We aimed to examine differentiating phenomenological characteristics in positive affect dynamics, and temporal relationships with pleasure towards current activity and meaning in life (MIL), among MDD, MDE/bipolar disorder and healthy controls using EMA.</p><p><strong>Method: </strong>Participants (<i>N</i> = 88, mean age 28.7 years, 69% female), including individuals with MDD (<i>n</i> = 29) and MDE/bipolar disorder (<i>n</i> = 29) and healthy controls (<i>n</i> = 30), were assessed for positive affect, pleasure and MIL 5 times daily over a 2-week period. Multilevel modelling analysis was conducted, with estimation of first-order autoregressive model structure and time-lagged relationship between pleasure and positive affect.</p><p><strong>Results: </strong>From 4632 EMA observations, positive affect dynamics (inertia, variability and instability) did not differ significantly across groups (all <i>P</i> > 0.05). Although all groups demonstrated a bidirectional relationship between positive affect and pleasure, for MDE/bipolar disorder, both pleasure_{<i>t</i> - 1} (<i>β</i> = -0.11, <i>t</i>[51.09] = -2.31, <i>P</i> = 0.025) and positive affect_{<i>t</i> - 1} (<i>β</i> = -0.13, <i>t</i>[56.54] = -2.30, <i>P</i> = 0.025) predicted subsequent MIL less significantly than for MDD and healthy controls.</p><p><strong>Conclusion: </strong>Individuals with MDE/bipolar disorder, but not MDD, had less self-reported MIL from positive affect and pleasure. There is little evidence that emotional experience alone characterises the pathophysiology between MDD and MDE/bipolar disorder; such investigation may be limited by within-group heterogeneity. Our findings provide a new perspective on using a time-series approach beyond bimodal measures in EMA to differentiate bipolar disorder/MDE and MDD.</p>","PeriodicalId":9038,"journal":{"name":"BJPsych Open","volume":"11 4","pages":"e141"},"PeriodicalIF":3.9,"publicationDate":"2025-07-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12247073/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144574790","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Perceptions of Brazil's Bolsa Família cash transfer programme, life opportunities and mental health in the lives of young adults from the outskirts of São Paulo: qualitative study.","authors":"Paulo Malvasi, Sara Evans-Lacko, Eva Cyhlarova, Alicia Matijasevich, David McDaid, Cristiane Silvestre Paula","doi":"10.1192/bjo.2025.10056","DOIUrl":"10.1192/bjo.2025.10056","url":null,"abstract":"<p><strong>Backgound: </strong>Cash transfer programmes (CTPs) provide financial support to alleviate poverty and promote economic stability. The Bolsa Família Programme (BFP), a Brazilian initiative and the world's largest CTP by number of beneficiaries, aims to improve living conditions. While poverty is closely linked to poor mental health, evidence regarding the specific effects of CTPs on young adults' mental health remains limited, underscoring the need for further research.</p><p><strong>Aims: </strong>To understand the meaning attributed to the BFP by young adults regarding their future aspirations and mental health, as well as perspectives from providers.</p><p><strong>Method: </strong>This qualitative study was conducted at the outskirts of São Paulo city, involving 12 in-depth interviews with young adults aged 18-24 years and 2 focus groups comprising 17 health and social assistance professionals.</p><p><strong>Results: </strong>Thematic analysis identified four themes according with interviews and focus groups: (a) perceptions about poverty (hopelessness and lack of opportunities); (b) impact of poverty on mental health (anxiety, unpredictability and hopelessness as consequences of living in poverty); (c) young adults' needs and aspirations (job opportunities as the main expectation for a better future); and (d) BFP limitations and opportunities for improvement (BFP perceived as just one of the survival strategies but not impacting life opportunities for young adults).</p><p><strong>Conclusions: </strong>The BFP was valued as essential for meeting poor families' basic needs. Employment opportunities were central to young adults' expectations, often causing anguish and anxiety. Expanding the BFP to include employment and income-generation policies could better support the mental health and life opportunities of vulnerable youth.</p>","PeriodicalId":9038,"journal":{"name":"BJPsych Open","volume":"11 4","pages":"e135"},"PeriodicalIF":3.9,"publicationDate":"2025-06-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12247056/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144526351","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Factors influencing physical healthcare quality for people with intellectual disabilities: psychiatry multidisciplinary team perspective.","authors":"Madiha Majid, Stefan Rennick-Egglestone, Bronwyn Harris, Ashok Roy, Hayley Crawford","doi":"10.1192/bjo.2025.10051","DOIUrl":"https://doi.org/10.1192/bjo.2025.10051","url":null,"abstract":"<p><strong>Background: </strong>There is a need for better collaborative care between services to improve healthcare provision for people with intellectual disabilities. In the UK, the learning disability psychiatry multidisciplinary team (MDT) is a specialist team responsible for providing and coordinating care for people with intellectual disabilities.</p><p><strong>Aims: </strong>To document learning disability MDT perspectives on factors influencing healthcare quality for people with intellectual disabilities.</p><p><strong>Method: </strong>Healthcare professionals who were members of a learning disability MDT within a National Health Service Trust in the West Midlands were purposively sampled for interview (<i>n</i> = 11). Participants included psychiatrists, nurses, occupational therapists and speech and language therapists. Data were analysed thematically using Braun and Clarke's six-stage approach.</p><p><strong>Results: </strong>Factors influencing the quality of healthcare provision included: the learning disability MDT working to overcome systemic barriers; the consequences of specific failures within mainstream healthcare services, such as diagnostic overshadowing; inadequate use of information collated in health passports; and inadequate capacity assessments of people with intellectual disabilities. Improvements in healthcare provision for people with intellectual disabilities require better accessibility to healthcare and better training for healthcare professionals so they can understand the health needs of people with intellectual disabilities.</p><p><strong>Conclusions: </strong>A rapid review of practices around health passports for people with intellectual disabilities should be conducted. Healthcare professionals working in mainstream healthcare services need an increased awareness of the harms of diagnostic overshadowing and inadequate capacity assessments. Conclusions are based on findings from MDTs within one health board; future work may focus on understanding perspectives from different teams.</p>","PeriodicalId":9038,"journal":{"name":"BJPsych Open","volume":"11 4","pages":"e137"},"PeriodicalIF":3.9,"publicationDate":"2025-06-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144526349","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Interrater reliability of the DSM-5 and ICD-11 Criterion A for PTSD and complex PTSD in parents of children with autism using the Life Events Checklist - ERRATUM.","authors":"Kylie Hinde, Gert Martin Hald, David Hallford, Theis Lange, Mikkel Christoffer Berg B Arendt, Silvia Pavan, David Austin","doi":"10.1192/bjo.2025.53","DOIUrl":"10.1192/bjo.2025.53","url":null,"abstract":"","PeriodicalId":9038,"journal":{"name":"BJPsych Open","volume":"11 4","pages":"e138"},"PeriodicalIF":3.9,"publicationDate":"2025-06-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12247068/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144526350","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A randomised controlled feasibility trial comparing culturally adapted psychoeducation and treatment as usual for persons with bipolar disorders in Nigeria.","authors":"Dung Ezekiel Jidong, M Ishrat Husain, Tarela Juliet Ike, Ameer Khoso, Maigari Yusufu Taru, Charles Nnaemeka Nwoga, Christopher Francis, Shadrack B Mwankon, John Ezekiel Jidong, Juliet Y Pwajok, Suleman Shakoor, Atta Muhammad Asif, Siqi Xue, Nusrat Husain","doi":"10.1192/bjo.2025.66","DOIUrl":"10.1192/bjo.2025.66","url":null,"abstract":"<p><strong>Background: </strong>Bipolar disorders are a major cause of disability worldwide, with most of the disease burden attributed to those in low- and middle-income countries, including Nigeria. There is limited evidence on culturally appropriate interventions for bipolar disorders in Nigeria.</p><p><strong>Aims: </strong>The study aims to examine the feasibility, and acceptability of culturally adapted psychoeducation (CaPE) for treating bipolar disorders.</p><p><strong>Method: </strong>A randomised controlled trial (RCT) compared CaPE plus treatment as usual (TAU) with TAU alone among 34 persons with bipolar disorders in Jos, Nigeria. CaPE comprised 12 group sessions of in-person psychoeducation lasting approximately 90 min each, delivered on a weekly basis by clinical researchers supervised by clinical psychologists and consultant psychiatrists. The primary outcome was feasibility, measured by participants' recruitment and retention rates. Other outcomes included acceptability as measured by the Service Satisfaction Scale (SSS), Brief Bipolar Disorder Symptom Scale (BBDSS), Patient Health Questionnaire (PHQ-9) and Quality-of-Life scale (EQ5D). Outcomes were assessed at baseline and weeks 12 and 24. Focus group (<i>n</i> = 10) and individual interviews (<i>n</i> = 5) were conducted with the CaPE + TAU group, recorded, transcribed verbatim and analysed using interpretative phenomenological analysis.</p><p><strong>Results: </strong>The CaPE+TAU group (<i>n</i> = 17) recorded a high participant recruitment and retention rate of 86% across 12 sessions, and also recorded a higher level of satisfaction with SSS compared with the TAU alone group; 87.5% indicated very satisfied compared with 66.7% indicated not sure in the TAU group. In terms of clinical outcomes, for PHQ-9 scores the intervention group showed a reduction from baseline to end of intervention (EOI) and follow-up, with differences of -12.01 and -7.39, respectively (both <i>P</i> < 0.001). The EQ5D index showed a notable improvement in the intervention group at both EOI and follow-up (<i>P</i> < 0.001). Lastly, BBDS scores decreased significantly in the CaPE+TAU group at both EOI and follow-up, with differences of -21.45 and -15.76 (both <i>P</i> < 0.001).</p><p><strong>Conclusions: </strong>The RCT of CaPE is a feasible, acceptable and culturally appropriate treatment option for bipolar disorders in Nigeria. Further adequately powered RCTs evaluating the intervention's clinical and cost-effectiveness are warranted.</p>","PeriodicalId":9038,"journal":{"name":"BJPsych Open","volume":"11 4","pages":"e133"},"PeriodicalIF":3.9,"publicationDate":"2025-06-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12247066/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144504825","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}