Epilepsy and psychosis: navigating through a complex intersection.

IF 3.9 3区医学 Q1 PSYCHIATRY

BJPsych Open Pub Date : 2025-06-26 DOI:10.1192/bjo.2025.70

Marco Mula, Andres M Kanner, Allan H Young, Annabella Di Giorgio, Andreas Schulze-Bonhage, Eugen Trinka

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引用次数: 0

Abstract

Background: The prevalence of psychiatric disorders in people with epilepsy is as high as 43% and, among them, psychoses represent a severe comorbidity.

Aims: This is a narrative review discussing the interplay between epilepsy and psychosis and identifying challenges in diagnosing and managing psychotic symptoms in epilepsy, focusing on the past 10 years.

Method: Articles published between June 2014 and December 2024 were identified through searches in PubMed using the search terms 'psychosis', 'seizure, epilepsy and convulsion', 'epile*', 'seizure*' and 'convuls*'.

Results: The association between epilepsy and psychosis was shown to be bidirectional, with people with psychosis being at increased risk of epilepsy. In epilepsy, psychotic symptoms may occur in three clinical scenarios, with clinical presentation and management varying in relationship to these: seizure-related (peri-ictal), treatment-related or independent of the former.

Conclusions: There are no guidelines for the management of psychotic symptoms in epilepsy, but it is possible to apply policies for the treatment of psychoses, taking into account the peculiarities and needs of people with epilepsy.

查看原文本刊更多论文

癫痫和精神病：通过一个复杂的交叉点导航。

背景：癫痫患者中精神障碍的患病率高达43%，其中精神病是一种严重的合并症。目的：这是一篇叙述性综述，讨论癫痫和精神病之间的相互作用，并确定癫痫中诊断和治疗精神病症状的挑战，重点是过去10年。方法：通过检索PubMed检索2014年6月至2024年12月期间发表的文章，检索词为“精神病”、“癫痫、癫痫和惊厥”、“癫痫*”、“癫痫*”和“惊厥*”。结果：癫痫和精神病之间的关系是双向的，精神病患者患癫痫的风险增加。在癫痫中，精神病性症状可能出现在三种临床情景中，其临床表现和处理与这些不同：癫痫发作相关（发作周期）、治疗相关或独立于前者。结论：目前尚无癫痫患者精神病性症状的管理指南，但考虑到癫痫患者的特点和需求，有可能应用政策来治疗精神病。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

BJPsych Open Medicine-Psychiatry and Mental Health

CiteScore

6.30

自引率

3.70%

发文量

610

审稿时长

16 weeks

期刊介绍： Announcing the launch of BJPsych Open, an exciting new open access online journal for the publication of all methodologically sound research in all fields of psychiatry and disciplines related to mental health. BJPsych Open will maintain the highest scientific, peer review, and ethical standards of the BJPsych, ensure rapid publication for authors whilst sharing research with no cost to the reader in the spirit of maximising dissemination and public engagement. Cascade submission from BJPsych to BJPsych Open is a new option for authors whose first priority is rapid online publication with the prestigious BJPsych brand. Authors will also retain copyright to their works under a creative commons license.