BioPsychoSocial Medicine最新文献

{"title":"Psychogenic fever and postural tachycardia syndrome among school-aged children and adolescents with fever of unknown origin","authors":"Y. Ishizaki, Yoshitoki Yanagimoto, Yuri Fujii, Mana Yamamoto, Kazunari Kaneko","doi":"10.1186/s13030-022-00238-1","DOIUrl":"https://doi.org/10.1186/s13030-022-00238-1","url":null,"abstract":"","PeriodicalId":9027,"journal":{"name":"BioPsychoSocial Medicine","volume":" ","pages":""},"PeriodicalIF":2.1,"publicationDate":"2022-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46003737","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Background factors involved in the epidemiology of functional constipation in the Japanese population: a cross-sectional study","authors":"Sayuri Yamamoto, W. Ohashi, Y. Yamaguchi, Shunsuke Inamoto, Akira Koshino, Tomoya Sugiyama, K. Nagao, Yasuhiro Tamura, S. Izawa, M. Ebi, Jun Usami, K. Hamano, Junko Izumi, Yoshinori Wakita, Y. Funaki, N. Ogasawara, M. Sasaki, M. Maekawa, K. Kasugai","doi":"10.1186/s13030-022-00237-2","DOIUrl":"https://doi.org/10.1186/s13030-022-00237-2","url":null,"abstract":"","PeriodicalId":9027,"journal":{"name":"BioPsychoSocial Medicine","volume":"16 1","pages":""},"PeriodicalIF":2.1,"publicationDate":"2021-10-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43571567","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The reliability and validity of the Japanese version of the Daily Record of Severity of Problems (J-DRSP) and Development of a Short-Form version (J-DRSP (SF)) to assess symptoms of premenstrual syndrome among Japanese women.","authors":"Yumie Ikeda,&nbsp;Miho Egawa,&nbsp;Kazuya Okamoto,&nbsp;Masaki Mandai,&nbsp;Yoshimitsu Takahashi,&nbsp;Takeo Nakayama","doi":"10.1186/s13030-021-00208-z","DOIUrl":"https://doi.org/10.1186/s13030-021-00208-z","url":null,"abstract":"<p><strong>Purpose: </strong>To assess the validity and reliability of the Japanese version of the Daily Record of Severity of Problems (J-DRSP, 24 items) for evaluating symptoms of premenstrual syndrome (PMS), and to develop a short form version of the J-DRSP.</p><p><strong>Methods: </strong>Using the \"DRSP-JAPAN\" smartphone app, we collected daily J-DRSP records from cycle day - 6 (CD - 6) to CD 10, with CD 1 representing the menstruation onset date. Factorial validity (exploratory factor analysis: EFA, confirmatory factor analysis: CFA) and criterion validity were examined, and test-retest reliability (intraclass correlation: ICC) evaluated. The short-form version of the J-DRSP was developed using classical test theory.</p><p><strong>Results: </strong>In total, 304 women participated and 243 recorded symptoms on at least 4 days spanning the week of the luteal phase (CD - 6 to CD 0) and 4 days spanning the week of the follicular phase (CD 4 to CD 10), with CD 0 set as the day before menstruation started. The EFA revealed a two-factor structure. Kaiser-Meyer-Olkin was 0.992, and Bartlett's test of sphericity chi-square was 3653.89 (P < 0.001). However, the model fitness of CFA was found to be suboptimal (comparative fit index (CFI): 0.83, root mean square error of approximation (RMSEA): 0.12). Total scores for J-DRSP and the sum scores for each subscale were higher on CD 0 than on CD 10 (p < 0.001), suggesting validity for some criteria. ICC values for the total J-DRSP score from CD 0 to CD - 1, and between CD 9 to CD 10, were 0.60 (95% CI: 0.48-0.72) and 0.76 (95% CI: 0.69-0.82), respectively. Having eliminated some original items after considering factor loading for each item, we developed an 8-item Short-Form J-DRSP (J-DRSP (SF)) comprising 2 factors (S-Psychological and S-Physical, 4 items for each). CFA showed a better model fit (CFI: 0.99, RMSEA: 0.048), and ICC values in the luteal and follicular phases were 0.61 (95%CI: 0.51-0.68) and 0.70 (95%CI: 0.62-0.77), respectively.</p><p><strong>Conclusion: </strong>The J-DRSP has moderate to good reliability and a certain level of validity. The 8-item J-DRSP (SF) has a two-factor structure and can be used effectively among Japanese women to assess their PMS symptoms.</p>","PeriodicalId":9027,"journal":{"name":"BioPsychoSocial Medicine","volume":"15 1","pages":"6"},"PeriodicalIF":2.1,"publicationDate":"2021-03-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1186/s13030-021-00208-z","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10296484","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Biopsychosocial medicine research trends: connecting clinical medicine, psychology, and public health.","authors":"Mutsuhiro Nakao,&nbsp;Gen Komaki,&nbsp;Kazuhiro Yoshiuchi,&nbsp;Hans-Christian Deter,&nbsp;Shin Fukudo","doi":"10.1186/s13030-020-00204-9","DOIUrl":"https://doi.org/10.1186/s13030-020-00204-9","url":null,"abstract":"","PeriodicalId":9027,"journal":{"name":"BioPsychoSocial Medicine","volume":"14 1","pages":"30"},"PeriodicalIF":2.1,"publicationDate":"2020-12-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1186/s13030-020-00204-9","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"38691244","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The psychosocial profile of family caregivers of children with chronic diseases: a cross-sectional study.","authors":"Filiberto Toledano-Toledano,&nbsp;David Luna","doi":"10.1186/s13030-020-00201-y","DOIUrl":"https://doi.org/10.1186/s13030-020-00201-y","url":null,"abstract":"<p><strong>Background: </strong>A family caregiver is defined as a person who has a significant emotional bond with the patient; this caregiver is a family member who is a part of the patient's family life cycle; offers emotional-expressive, instrumental, and tangible support; and provides assistance and comprehensive care during the chronic illness, acute illness, or disability of a child, adult, or elderly person. The objectives of this study were to identify the psychosocial profiles of family caregivers of children with chronic diseases and to establish the relationship between these profiles and sociodemographic variables.</p><p><strong>Methods: </strong>A cross-sectional study was conducted involving 401 family caregivers of children with chronic diseases at the National Institute of Health in Mexico City. The participants responded to the Sociodemographic Variables Questionnaire (Q-SV) for research on family caregivers of children with chronic disease and a battery of 7 instruments that examined anxiety, caregiver burden, family support, depression, resilience, parental stress, and the World Health Organization Well-Being Index<i>.</i></p><p><strong>Results: </strong>A hierarchical cluster analysis and its confirmation through a nonhierarchical cluster analysis confirmed two profiles of caregivers of pediatric patients with chronic diseases. Profile 1, called <i>Vulnerability of family caregivers</i>, is characterized by high levels of anxiety, depression, parental stress and caregiver burden, accompanied by low levels of family support, resilience, and well-being. Profile 2, called <i>Adversity of family caregivers</i>, shows an inverse pattern, with high levels of family support, resilience, and well-being and low levels of anxiety, depression, parental stress and caregiver burden. The sociodemographic characteristics are similar for both profiles, with the exception of the caregiver's family type. Profile 1 shows more single-parent caregivers, while profile 2 includes more caregivers with a nuclear family. However, the type of family did not reach significance for predicting the caregiver's profile in a bivariate logistic regression model.</p><p><strong>Conclusions: </strong>The psychosocial profile of family caregivers of children with chronic diseases can be structured according to their psychosocial characteristics. Although no causal factors were detected that define criteria for belonging to one or another profile, the characteristics identified for each indicate the need for specific and differentiated intervention strategies for families facing adversity, risk and vulnerability during a child's disease.</p>","PeriodicalId":9027,"journal":{"name":"BioPsychoSocial Medicine","volume":"14 ","pages":"29"},"PeriodicalIF":2.1,"publicationDate":"2020-10-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1186/s13030-020-00201-y","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"38536785","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Personality traits mediate the association between perceived parental bonding and well-being in adult volunteers from the community.","authors":"Akiko Murakoshi,&nbsp;Nobuyuki Mitsui,&nbsp;Jiro Masuya,&nbsp;Yota Fujimura,&nbsp;Shinji Higashi,&nbsp;Ichiro Kusumi,&nbsp;Takeshi Inoue","doi":"10.1186/s13030-020-00198-4","DOIUrl":"https://doi.org/10.1186/s13030-020-00198-4","url":null,"abstract":"<p><strong>Background: </strong>Previous studies reported that subjective well-being in adulthood correlates with perceived parental bonding in childhood as well as personality traits. However, whether personality traits mediate the effect of perceived parental bonding on well-being or not has not been reported to date. In this study, we hypothesized that 'parental care and overprotection' in childhood affect 'well-being' in adulthood through various 'personality traits', and analyzed this using structural equation modeling.</p><p><strong>Methods: </strong>A total of 402 adult volunteers from the community provided responses to the following questionnaires: 1) Parental Bonding Instrument, 2) Temperament and Character Inventory, and 3) The Subjective Well-being Inventory. Two structural equation models were designed and the maximum likelihood estimation method was used for covariance structure analysis.</p><p><strong>Results: </strong>Parental care in childhood directly increased well-being in adulthood and indirectly increased it through personality traits (harm avoidance, reward dependence, and self-directedness). Parental overprotection in childhood had no direct effect on well-being in adulthood but decreased well-being in adulthood indirectly through personality traits (harm avoidance, reward dependence, and self-directedness) and increased it through one personality trait (self-transcendence).</p><p><strong>Conclusions: </strong>This study showed that the influences of perceived parental bonding on well-being in adulthood are mediated by self-directedness, harm avoidance, reward dependence, and self-transcendence among the seven personality dimensions evaluated by the Temperament and Character Inventory.</p>","PeriodicalId":9027,"journal":{"name":"BioPsychoSocial Medicine","volume":"14 ","pages":"28"},"PeriodicalIF":2.1,"publicationDate":"2020-10-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1186/s13030-020-00198-4","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"38518369","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Educational supportive group therapy and the quality of life of hemodialysis patients.","authors":"Sajad Mansouri,&nbsp;Amir Jalali,&nbsp;Mahmoud Rahmati,&nbsp;Nader Salari","doi":"10.1186/s13030-020-00200-z","DOIUrl":"https://doi.org/10.1186/s13030-020-00200-z","url":null,"abstract":"<p><strong>Background: </strong>In addition to physical, mental, and social condition, ESRD and hemodialysis affect the quality of life of patients as well. Psychotherapy and non-pharmaceutical interventions are effective measures to add meaning to life, create a goal and motivation in life, and improve the quality of life in chronic patients. The effect of educational and supportive group therapy on the quality of life (QOL) of hemodialysis patients was examined.</p><p><strong>Methods: </strong>The study was carried out as an interventional quasi-experimental study with the participation of 64 patients who were selected through convenience sampling and based on the patient's hemodialysis days (Saturday, Monday, and Wednesday patients as an experimental group and Sunday, Tuesday, and Thursday patients as a control group). There were 32 patients in each group. The experimental group received eight 50 min sessions including two sessions per week. The control group received the normal interventions. The participants were assessed using a demographics form and Kidney Disease Quality of Life Short Form before, immediately after, and 1 month after the intervention. The collected data was analyzed using SPSS (v.24).</p><p><strong>Results: </strong>The mean QOL scores of the experimental group before, immediately after, and 4 weeks after the intervention were 36.99, 43.3, and 44.9 respectively. Those of the control group were 36.39, 37.2, and 37.1 respectively. There was no significant difference between the two groups before the intervention (<i>P</i> > 0.05); however, the difference between the two groups was significant immediately after and 4 weeks after the intervention (<i>P</i> = 0.0001). The trend of score change in the experimental group was also significant (<i>p</i> < 0.05), and Tukey ad-hoc test showed significant differences between the scores before intervention and those immediately after and 4 weeks after the intervention (<i>p</i> < 0.05).</p><p><strong>Conclusion: </strong>In general, educational and supportive group therapy can expand the interpersonal relationships of hemodialysis patients and positively affect their quality of life.</p>","PeriodicalId":9027,"journal":{"name":"BioPsychoSocial Medicine","volume":"14 ","pages":"27"},"PeriodicalIF":2.1,"publicationDate":"2020-10-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1186/s13030-020-00200-z","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"38502752","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Personal values in adolescence and their associations with metabolic biomarkers in adulthood: a Japanese population-based study.","authors":"Natsu Sasaki,&nbsp;Kazuhiro Watanabe,&nbsp;Norito Kawakami","doi":"10.1186/s13030-020-00197-5","DOIUrl":"https://doi.org/10.1186/s13030-020-00197-5","url":null,"abstract":"<p><strong>Background: </strong>Personal values, which are formed in early life, can have an impact on health outcome later in life.</p><p><strong>Objective: </strong>The aim of this study is to investigate the relation between personal values in adolescence and bio-indicators related to metabolic syndrome (MetS) in adulthood.</p><p><strong>Participants and methods: </strong>The longitudinal data used was from the Japanese Study on Stratification, Health, Income, and Neighborhood (J-SHINE). Personal values in adolescence were retrospectively obtained in 2017 from a self-reporting questionnaire, composed of value priorities and commitment to the values. Venous samples were collected in 2012 for low and high-density lipoprotein (LDL, HDL) cholesterol and hemoglobin A1c (HbA1c). Body mass index (BMI), waist circumference and systolic and diastolic blood pressure (SBP, DBP) were also measured. The associations of each variable were examined by partial correlation analysis. In addition, multiple linear regression analysis was conducted to examine overall associations between personal values and the sum of standardized scores (Z-score) of the biomarkers as a proxy of MetS.</p><p><strong>Results: </strong>The total population (<i>n</i> = 668) included 261 men and 407 women. For men, the personal value priority of \"Having influence on society\" was associated with high HDL cholesterol (0.133, <i>p</i> = 0.032) and \"Cherishing familiar people\" with low waist circumference (<i>r</i> = -0.129, <i>p</i> = 0.049), low SBP, and high DBP (<i>r</i> = -0.135, <i>p</i> = 0.039; <i>r</i> = 0.134, <i>p</i> = 0.041). For women, \"Not bothering others\" was associated with high SBP and low DBP (<i>r</i> = 0.125, <i>p</i> = 0.015; <i>r</i> = -0.123, <i>p</i> = 0.017). \"Economically succeeding\" was associated with a worse outcome (β = 0.162, <i>p</i> = 0.042) in men.</p><p><strong>Conclusions: </strong>Although some significant associations were found between personal values in adolescence and MetS-related markers in adulthood, the overall associations were not strong. Culturally prevailing values were likely to be associated with a good outcome of metabolic health.</p>","PeriodicalId":9027,"journal":{"name":"BioPsychoSocial Medicine","volume":"14 ","pages":"26"},"PeriodicalIF":2.1,"publicationDate":"2020-10-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1186/s13030-020-00197-5","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"38572710","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Association between polypharmacy and the persistence of delirium: a retrospective cohort study.","authors":"Ken Kurisu,&nbsp;Daisuke Miyabe,&nbsp;Yoshiko Furukawa,&nbsp;Osamu Shibayama,&nbsp;Kazuhiro Yoshiuchi","doi":"10.1186/s13030-020-00199-3","DOIUrl":"https://doi.org/10.1186/s13030-020-00199-3","url":null,"abstract":"<p><strong>Background: </strong>Although the association between polypharmacy and the occurrence of delirium has been well studied, the influence of polypharmacy on the persistence of delirium remains unclear. We aimed to explore the effect of polypharmacy on the persistence of delirium.</p><p><strong>Methods: </strong>This retrospective cohort study was conducted at a tertiary hospital. The medical records of patients diagnosed with delirium who were referred to the Department of Psychosomatic Medicine were reviewed. Presentation with delirium on day 3 was set as the outcome in this study. We counted the number of drugs prescribed on the date of referral, excluding general infusion fluids, nutritional or electrolytic products, and psychotropics. To define polypharmacy, we developed a classification and regression tree (CART) model and drew a receiver operating characteristic (ROC) curve. The odds ratio (OR) of polypharmacy for the persistence of delirium on day 3 was calculated using a logistic regression model with the propensity score as a covariate.</p><p><strong>Results: </strong>We reviewed the data of 113 patients. The CART model and ROC curve indicated an optimal polypharmacy cutoff of six drugs. Polypharmacy was significantly associated with the persistence of delirium both before [OR, 3.02; 95% confidence interval (CI), 1.39-6.81; <i>P</i> = 0.0062] and after (OR, 3.19; 95% CI, 1.32-8.03; <i>P</i> = 0.011) propensity score adjustment.</p><p><strong>Conclusion: </strong>We discovered an association between polypharmacy and worsening courses of delirium and hypothesize that polypharmacy might be a prognostic factor for delirium.</p>","PeriodicalId":9027,"journal":{"name":"BioPsychoSocial Medicine","volume":"14 ","pages":"25"},"PeriodicalIF":2.1,"publicationDate":"2020-10-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1186/s13030-020-00199-3","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"38572709","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Higher galectin-3 levels are independently associated with lower anxiety in patients with risk factors for heart failure.","authors":"Monika Sadlonova,&nbsp;Thomas Meyer,&nbsp;Lutz Binder,&nbsp;Rolf Wachter,&nbsp;Frank Edelmann,&nbsp;Christoph Herrmann-Lingen","doi":"10.1186/s13030-020-00195-7","DOIUrl":"https://doi.org/10.1186/s13030-020-00195-7","url":null,"abstract":"<p><strong>Background: </strong>Galectin-3 promotes the proliferation of neural progenitor cells and is engaged in cell-cell adhesion, cell-matrix interactions, and macrophage activation. In addition, in patients with heart failure this carbohydrate-binding protein is a known prognostic marker for cardiovascular mortality. However, its association with psychological variables has not been investigated so far.</p><p><strong>Methods: </strong>Using data from the multicenter, observational Diast-CHF (Diagnostic Trial on Prevalence and Clinical Course of Diastolic Dysfunction and Heart Failure) trial, we studied in participants with cardiovascular risk factors (<i>n</i> = 1260, age 66.7 ± 8.0 years, males 51%, left ventricular ejection fraction 60.0 ± 8.1%) the relationship between serum concentrations of galectin-3 and anxiety. Galectin-3 levels were measured by means of a sandwich enzyme-linked immunosorbent assay, and anxiety was assessed using the Hospital Anxiety and Depression Scale (HADS).</p><p><strong>Results: </strong>In univariate analysis, there was a weak but significant inverse correlation between galectin-3 and HADS anxiety (rho = - 0.076; <i>p</i> = 0.008). Linear regression models adjusted for sex, age, body-mass index, estimated glomerular filtration rate, left ventricular ejection fraction, 6-min walking distance, the 36-item Short-Form Health Survey (SF-36) subscale physical functioning, and known biomarkers for heart failure confirmed that serum galectin-3 significantly and independently predicted self-rated anxiety (B = -2.413; 95%CI = -2.413--4.422; <i>p</i> = 0.019).</p><p><strong>Conclusion: </strong>In patients with cardiovascular risk factors, serum concentrations of galectin-3 showed an inverse association with anxiety, which was independent of both the severity of physical impairment and established risk factors for the progression of heart failure.</p>","PeriodicalId":9027,"journal":{"name":"BioPsychoSocial Medicine","volume":"14 ","pages":"24"},"PeriodicalIF":2.1,"publicationDate":"2020-10-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1186/s13030-020-00195-7","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"38460803","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}