BioPsychoSocial Medicine最新文献

{"title":"Personal values in adolescence and their associations with metabolic biomarkers in adulthood: a Japanese population-based study.","authors":"Natsu Sasaki,&nbsp;Kazuhiro Watanabe,&nbsp;Norito Kawakami","doi":"10.1186/s13030-020-00197-5","DOIUrl":"https://doi.org/10.1186/s13030-020-00197-5","url":null,"abstract":"<p><strong>Background: </strong>Personal values, which are formed in early life, can have an impact on health outcome later in life.</p><p><strong>Objective: </strong>The aim of this study is to investigate the relation between personal values in adolescence and bio-indicators related to metabolic syndrome (MetS) in adulthood.</p><p><strong>Participants and methods: </strong>The longitudinal data used was from the Japanese Study on Stratification, Health, Income, and Neighborhood (J-SHINE). Personal values in adolescence were retrospectively obtained in 2017 from a self-reporting questionnaire, composed of value priorities and commitment to the values. Venous samples were collected in 2012 for low and high-density lipoprotein (LDL, HDL) cholesterol and hemoglobin A1c (HbA1c). Body mass index (BMI), waist circumference and systolic and diastolic blood pressure (SBP, DBP) were also measured. The associations of each variable were examined by partial correlation analysis. In addition, multiple linear regression analysis was conducted to examine overall associations between personal values and the sum of standardized scores (Z-score) of the biomarkers as a proxy of MetS.</p><p><strong>Results: </strong>The total population (<i>n</i> = 668) included 261 men and 407 women. For men, the personal value priority of \"Having influence on society\" was associated with high HDL cholesterol (0.133, <i>p</i> = 0.032) and \"Cherishing familiar people\" with low waist circumference (<i>r</i> = -0.129, <i>p</i> = 0.049), low SBP, and high DBP (<i>r</i> = -0.135, <i>p</i> = 0.039; <i>r</i> = 0.134, <i>p</i> = 0.041). For women, \"Not bothering others\" was associated with high SBP and low DBP (<i>r</i> = 0.125, <i>p</i> = 0.015; <i>r</i> = -0.123, <i>p</i> = 0.017). \"Economically succeeding\" was associated with a worse outcome (β = 0.162, <i>p</i> = 0.042) in men.</p><p><strong>Conclusions: </strong>Although some significant associations were found between personal values in adolescence and MetS-related markers in adulthood, the overall associations were not strong. Culturally prevailing values were likely to be associated with a good outcome of metabolic health.</p>","PeriodicalId":9027,"journal":{"name":"BioPsychoSocial Medicine","volume":"14 ","pages":"26"},"PeriodicalIF":2.1,"publicationDate":"2020-10-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1186/s13030-020-00197-5","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"38572710","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Association between polypharmacy and the persistence of delirium: a retrospective cohort study.","authors":"Ken Kurisu,&nbsp;Daisuke Miyabe,&nbsp;Yoshiko Furukawa,&nbsp;Osamu Shibayama,&nbsp;Kazuhiro Yoshiuchi","doi":"10.1186/s13030-020-00199-3","DOIUrl":"https://doi.org/10.1186/s13030-020-00199-3","url":null,"abstract":"<p><strong>Background: </strong>Although the association between polypharmacy and the occurrence of delirium has been well studied, the influence of polypharmacy on the persistence of delirium remains unclear. We aimed to explore the effect of polypharmacy on the persistence of delirium.</p><p><strong>Methods: </strong>This retrospective cohort study was conducted at a tertiary hospital. The medical records of patients diagnosed with delirium who were referred to the Department of Psychosomatic Medicine were reviewed. Presentation with delirium on day 3 was set as the outcome in this study. We counted the number of drugs prescribed on the date of referral, excluding general infusion fluids, nutritional or electrolytic products, and psychotropics. To define polypharmacy, we developed a classification and regression tree (CART) model and drew a receiver operating characteristic (ROC) curve. The odds ratio (OR) of polypharmacy for the persistence of delirium on day 3 was calculated using a logistic regression model with the propensity score as a covariate.</p><p><strong>Results: </strong>We reviewed the data of 113 patients. The CART model and ROC curve indicated an optimal polypharmacy cutoff of six drugs. Polypharmacy was significantly associated with the persistence of delirium both before [OR, 3.02; 95% confidence interval (CI), 1.39-6.81; <i>P</i> = 0.0062] and after (OR, 3.19; 95% CI, 1.32-8.03; <i>P</i> = 0.011) propensity score adjustment.</p><p><strong>Conclusion: </strong>We discovered an association between polypharmacy and worsening courses of delirium and hypothesize that polypharmacy might be a prognostic factor for delirium.</p>","PeriodicalId":9027,"journal":{"name":"BioPsychoSocial Medicine","volume":"14 ","pages":"25"},"PeriodicalIF":2.1,"publicationDate":"2020-10-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1186/s13030-020-00199-3","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"38572709","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Higher galectin-3 levels are independently associated with lower anxiety in patients with risk factors for heart failure.","authors":"Monika Sadlonova,&nbsp;Thomas Meyer,&nbsp;Lutz Binder,&nbsp;Rolf Wachter,&nbsp;Frank Edelmann,&nbsp;Christoph Herrmann-Lingen","doi":"10.1186/s13030-020-00195-7","DOIUrl":"https://doi.org/10.1186/s13030-020-00195-7","url":null,"abstract":"<p><strong>Background: </strong>Galectin-3 promotes the proliferation of neural progenitor cells and is engaged in cell-cell adhesion, cell-matrix interactions, and macrophage activation. In addition, in patients with heart failure this carbohydrate-binding protein is a known prognostic marker for cardiovascular mortality. However, its association with psychological variables has not been investigated so far.</p><p><strong>Methods: </strong>Using data from the multicenter, observational Diast-CHF (Diagnostic Trial on Prevalence and Clinical Course of Diastolic Dysfunction and Heart Failure) trial, we studied in participants with cardiovascular risk factors (<i>n</i> = 1260, age 66.7 ± 8.0 years, males 51%, left ventricular ejection fraction 60.0 ± 8.1%) the relationship between serum concentrations of galectin-3 and anxiety. Galectin-3 levels were measured by means of a sandwich enzyme-linked immunosorbent assay, and anxiety was assessed using the Hospital Anxiety and Depression Scale (HADS).</p><p><strong>Results: </strong>In univariate analysis, there was a weak but significant inverse correlation between galectin-3 and HADS anxiety (rho = - 0.076; <i>p</i> = 0.008). Linear regression models adjusted for sex, age, body-mass index, estimated glomerular filtration rate, left ventricular ejection fraction, 6-min walking distance, the 36-item Short-Form Health Survey (SF-36) subscale physical functioning, and known biomarkers for heart failure confirmed that serum galectin-3 significantly and independently predicted self-rated anxiety (B = -2.413; 95%CI = -2.413--4.422; <i>p</i> = 0.019).</p><p><strong>Conclusion: </strong>In patients with cardiovascular risk factors, serum concentrations of galectin-3 showed an inverse association with anxiety, which was independent of both the severity of physical impairment and established risk factors for the progression of heart failure.</p>","PeriodicalId":9027,"journal":{"name":"BioPsychoSocial Medicine","volume":"14 ","pages":"24"},"PeriodicalIF":2.1,"publicationDate":"2020-10-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1186/s13030-020-00195-7","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"38460803","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Shitsu-taikan-sho (alexisomia): a historical review and its clinical importance.","authors":"Takakazu Oka","doi":"10.1186/s13030-020-00193-9","DOIUrl":"https://doi.org/10.1186/s13030-020-00193-9","url":null,"abstract":"<p><p>\"Shitsu-taikan-sho\" is a clinical concept that refers to characteristics of having difficulty in the awareness and expression of somatic feelings or sensations. This concept was first proposed in 1979 by Dr. Yujiro Ikemi, the founder of psychosomatic medicine in Japan, as a characteristic observed in patients with psychosomatic diseases, i.e. physical diseases in which psychosocial factors are closely involved in their onset and progress. Soon after Dr. Ikemi introduced to Japan the concept of alexithymia, coined by P. E. Sifneos in 1973, he noticed that patients with psychosomatic diseases have difficulty in describing not only their emotions, but also somatic feelings and sensations. Dr. Ikemi proposed naming the concept of the trait of lacking somatic awareness \"shitsu-taikan-sho\" in Japanese (\"alexisomia\" in English), meaning \"shitsu\" a lack, \"taikan\" bodily feelings/sensations, and \"sho\" condition/symptoms. Dr. Ikemi observed characteristics of both alexithymia and alexisomia in patients with psychosomatic diseases, but considered alexisomia to have a more fundamental pathophysiological role in the understanding of psychosomatic diseases. He also emphasized the importance of treating alexisomia when treating psychosomatic diseases. Recently, alexisomia has again come into focus for various reasons. One is the availability of the Shitsu-taikan-sho Scale (STSS), a self-rating questionnaire to evaluate alexisomic tendency. Another is recent advances in basic research on interoception. The former will facilitate clinical studies on alexisomia, and the latter will enable a deeper understanding of alexisomia. This article is an overview of the historical development of the concept of alexisomia which was conceptualized by Dr. Ikemi, introduces the STSS, and discusses the current understanding and clinical importance of alexisomia in psychosomatic medicine.</p>","PeriodicalId":9027,"journal":{"name":"BioPsychoSocial Medicine","volume":"14 ","pages":"23"},"PeriodicalIF":2.1,"publicationDate":"2020-09-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1186/s13030-020-00193-9","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"38440165","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The prognosis and prevention measures for mental health in COVID-19 patients: through the experience of SARS.","authors":"Guo Heng Mo,&nbsp;Zi Xuan Wang,&nbsp;Xiao Si Chen,&nbsp;Qunguang Jiang","doi":"10.1186/s13030-020-00196-6","DOIUrl":"https://doi.org/10.1186/s13030-020-00196-6","url":null,"abstract":"<p><p>Due to the high pathogenicity and mortality, the COVID-19 disaster caused global panic and anxiety. At present, diagnosis and treatment are of great concern. As time progresses, however, the sequelae caused by many other organ system complications and treatments will become increasingly obvious, and psychosomatic symptoms are one of these changes with great potential impact. Studies have shown that symptoms like poor sleep quality, anxiety and even delirium are not uncommon in patients during isolation. By summarizing the follow-up study on mental and psychological health of SARS in the past 10 years, and combining the characteristics of the existing cases of COVID-19, we will provide suggestions for the prevention and treatment of psychological diseases in clinical practice.</p>","PeriodicalId":9027,"journal":{"name":"BioPsychoSocial Medicine","volume":"14 ","pages":"22"},"PeriodicalIF":2.1,"publicationDate":"2020-09-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1186/s13030-020-00196-6","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"38418073","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Alexithymia 3.0: reimagining alexithymia from a medical perspective","authors":"R. Lane","doi":"10.1186/s13030-020-00191-x","DOIUrl":"https://doi.org/10.1186/s13030-020-00191-x","url":null,"abstract":"","PeriodicalId":9027,"journal":{"name":"BioPsychoSocial Medicine","volume":"14 1","pages":"1-8"},"PeriodicalIF":2.1,"publicationDate":"2020-09-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1186/s13030-020-00191-x","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49601169","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Affective agnosia: a core affective processing deficit in the alexithymia spectrum","authors":"R. Lane, M. Solms, K. Weihs, Alex Hishaw, Ryan Smith","doi":"10.1186/s13030-020-00184-w","DOIUrl":"https://doi.org/10.1186/s13030-020-00184-w","url":null,"abstract":"","PeriodicalId":9027,"journal":{"name":"BioPsychoSocial Medicine","volume":"14 1","pages":"1-14"},"PeriodicalIF":2.1,"publicationDate":"2020-09-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1186/s13030-020-00184-w","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41539040","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Development of a new Japanese version of the Clinical Impairment Assessment Questionnaire.","authors":"Takeshi Horie,&nbsp;Maiko Hiraide,&nbsp;Shu Takakura,&nbsp;Tomokazu Hata,&nbsp;Nobuyuki Sudo,&nbsp;Kazuhiro Yoshiuchi","doi":"10.1186/s13030-020-00194-8","DOIUrl":"https://doi.org/10.1186/s13030-020-00194-8","url":null,"abstract":"<p><strong>Background: </strong>The Clinical Impairment Assessment questionnaire (CIA) is used to measure the severity of psychosocial impairment in patients with eating disorders. The purpose of the present study was to develop a new Japanese version of the CIA (CIA-J) and to evaluate its reliability and validity.</p><p><strong>Methods: </strong>We translated the sixteen items of the CIA into Japanese, back-translated them into English, and had them verified by a native English speaking professional editor. Participants were 152 Japanese-speaking patients (30.4 ± 10.6 years) under treatment for eating disorders and 173 healthy controls (29.5 ± 8.3 years). In addition to the CIA-J, the participants were asked to answer the Eating Attitudes Test (EAT26), The Positive and Negative Affect Schedule (PANAS), and the Hospital Anxiety and Depression Scale (HADS). We performed confirmatory factor analyses to evaluate the factor structure, calculated the Cronbach's alphas of the CIA-J to assess the reliability, and calculated the correlation coefficients between the CIA-J score and those of EAT26, PANAS, and HADS to assess concurrent validity. We also used a Kruskal-Wallis test followed by Steel-Dwass test to compare the scores of the subtypes of eating disorders and the healthy control group.</p><p><strong>Results: </strong>A three-factor structure was obtained, similar to the original version. The Cronbach's alphas of both the global and subscale scores of the CIA-J were high. The CIA-J had significant positive correlations with the EAT26, the negative affect subscale of the PANAS, and the HADS. The global and subscale scores for all subtypes of eating disorders were significantly higher than those of the healthy control group.</p><p><strong>Conclusions: </strong>The CIA-J was determined to be reliable and valid for assessing the severity of psychosocial impairment in patients with eating disorders.</p>","PeriodicalId":9027,"journal":{"name":"BioPsychoSocial Medicine","volume":"14 ","pages":"19"},"PeriodicalIF":2.1,"publicationDate":"2020-08-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1186/s13030-020-00194-8","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"38343129","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Correction to: Very long chain fatty acids are an important marker of nutritional status in patients with anorexia nervosa: a case control study.","authors":"Miki Shimizu,&nbsp;Keisuke Kawai,&nbsp;Makoto Yamashita,&nbsp;Masayasu Shoji,&nbsp;Shu Takakura,&nbsp;Tomokazu Hata,&nbsp;Megumi Nakashima,&nbsp;Keita Tatsushima,&nbsp;Kazunari Tanaka,&nbsp;Nobuyuki Sudo","doi":"10.1186/s13030-020-00192-w","DOIUrl":"https://doi.org/10.1186/s13030-020-00192-w","url":null,"abstract":"<p><p>[This corrects the article DOI: 10.1186/s13030-020-00186-8.].</p>","PeriodicalId":9027,"journal":{"name":"BioPsychoSocial Medicine","volume":"14 ","pages":"18"},"PeriodicalIF":2.1,"publicationDate":"2020-08-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1186/s13030-020-00192-w","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"38293591","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The association of depression, loneliness and internet addiction levels in patients with acne vulgaris.","authors":"Coşkun Öztekin,&nbsp;Aynure Öztekin","doi":"10.1186/s13030-020-00190-y","DOIUrl":"https://doi.org/10.1186/s13030-020-00190-y","url":null,"abstract":"<p><strong>Background: </strong>Acne vulgaris is a very common skin disorder that has negative effects on the mood, self image and social relations of the patients. We want to evaluate the effects of acne vulgaris and its severity on depression, loneliness, internet addiction levels, and the quality of life of young adult females.</p><p><strong>Methods: </strong>Two hundred three female acne vulgaris patients and 202 healthy controls who admitted to the dermatology clinic of a university hospital formed the study sample. Global Acne Grading System (GAGS) was used to assess the severity of acne. The Young Internet Addiction Scale-Short Form (YIAS-SF), The Acne Quality of Life Scale (AQLS), The University of California Los Angeles-Loneliness Scale (UCLA-LS), and The Beck Depression Inventory (BDI) were used to collect information about the patients.</p><p><strong>Results: </strong>The median BDI and the mean UCLA-LS and YIAS-SF scores were higher in the Acne group than those in the control group. The correlations between acne severity and the 3 scales were not significant but the correlations between AQLS and BDI, UCLA-LS, and YIAS-SF were highly significant. In multiple regression analysis, age and the BDI score predicted the YIAS-SF score significantly.</p><p><strong>Conclusions: </strong>Our findings support the previous findings that acne vulgaris patients are prone to depression and loneliness, and expand these findings to the vulnerability against internet addiction. Loneliness and depression should be assessed and, if found, targeted by psychological means to prevent internet addiction in acne vulgaris patients.</p>","PeriodicalId":9027,"journal":{"name":"BioPsychoSocial Medicine","volume":"14 ","pages":"17"},"PeriodicalIF":2.1,"publicationDate":"2020-08-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1186/s13030-020-00190-y","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"38255772","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}