BioPsychoSocial Medicine最新文献

{"title":"Effects of short-term existential group therapy for breast Cancer patients.","authors":"Chizu Nakamura,&nbsp;Masatoshi Kawase","doi":"10.1186/s13030-021-00225-y","DOIUrl":"https://doi.org/10.1186/s13030-021-00225-y","url":null,"abstract":"<p><strong>Objectives: </strong>Cancer patients who suffer from existential difficulties, including fear of death, isolation, or loss of human relationships, try to accept these fears by exploring the meaning of their life. In particular, early psychological intervention for patients prevents them from psychosocial maladjustment afterwards. Therefore, we have developed the Short-term Existential Group Therapy Program (Short-term EGP) for cancer patients, focusing on relief of existential or spiritual suffering and/or pain. This study aims to statistically evaluate the effects of this program on breast cancer patients within the first year after cancer diagnosis.</p><p><strong>Methods: </strong>Thirty-one patients completed our research program. A ninety-minute therapeutic group session was held once a week for 5 weeks. We performed the above assessments three times: just before and after the intervention, as well as a month after the end of intervention. Outcome assessment included measures of spiritual well-being (SELT-M), Mental Adjustment to Cancer (MAC) and Profile of Mood States (POMS).</p><p><strong>Results: </strong>The SELT-M \"Overall QOL\" scores were significantly increased after intervention, and these scores were maintained a month after intervention, particularly in those with high MAC \"Hopelessness\" scores. Subscales of the SELT-M scores were significantly increased after intervention, and these scores were maintained up to a month after intervention.</p><p><strong>Conclusion: </strong>Short-term EGP intervention could be effective in helping patients relieve their existential distress. Some of the treatment effects were maintained a month after the end of the intervention. In addition, Short-term EGP could be particularly effective for those patients who feel hopelessness after cancer diagnosis.</p><p><strong>Trial registration: </strong>Retrospectively registered. University Hospital Medical Information Network (UMIN CTR) UMIN000040651 . Registered June 4, 2020.</p>","PeriodicalId":9027,"journal":{"name":"BioPsychoSocial Medicine","volume":" ","pages":"24"},"PeriodicalIF":2.1,"publicationDate":"2021-11-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8626958/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39939112","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Cognitive behavioral treatment for irritable bowel syndrome: a recent literature review.","authors":"Nagisa Sugaya,&nbsp;Kentaro Shirotsuki,&nbsp;Mutsuhiro Nakao","doi":"10.1186/s13030-021-00226-x","DOIUrl":"https://doi.org/10.1186/s13030-021-00226-x","url":null,"abstract":"<p><p>Irritable bowel syndrome (IBS) is a gastrointestinal psychosomatic disorder that often develops and worsens with stress. Hence, it is important to treat it from both, its physical and mental aspects. We reviewed recent research on cognitive-behavioral therapy (CBT)-one of the most widely studied psychological treatments for IBS-since it focuses on addressing the cognitions and behaviors associated with IBS symptoms, and combines diverse content, such as cognitive techniques, exposure, stress management, and mindfulness, whose effects have been widely studied. Research on CBT for IBS varies not only in terms of content of the interventions, but also in terms of implementation (individual or group, face-to-face or online). Internet-delivered CBT has recently shown the possibility of providing more accessible and cost-effective psychological intervention to IBS patients in formats, other than face-to-face. In recent years, many standardized scales that allow for IBS-specific psychological assessments have been used in clinical studies of CBT for IBS. Tools that competently deliver effective interventions and properly measure their effectiveness are expected to spread to many people suffering from IBS.</p>","PeriodicalId":9027,"journal":{"name":"BioPsychoSocial Medicine","volume":" ","pages":"23"},"PeriodicalIF":2.1,"publicationDate":"2021-11-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8626893/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39672095","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A systematic review of the effect of sleep interventions on presenteeism.","authors":"Yuta Takano,&nbsp;Suguru Iwano,&nbsp;Shuntaro Aoki,&nbsp;Norihito Nakano,&nbsp;Yuji Sakano","doi":"10.1186/s13030-021-00224-z","DOIUrl":"https://doi.org/10.1186/s13030-021-00224-z","url":null,"abstract":"<p><strong>Background: </strong>Sleep problems interfere with work performance. Decreased work productivity due to health problems is defined as presenteeism. Although empirical data on the improvement of presenteeism by sleep interventions have been published, a systematic review elucidating whether there is a difference in the improvement of presenteeism across various types of sleep interventions has not yet been published. This systematic review of studies aimed to clarify which sleep interventions are more likely to be effective in improving presenteeism.</p><p><strong>Methods: </strong>The electronic databases PubMed, PsycINFO, and MEDLINE were used to perform a literature search (the start and end search dates were October 20, 2019, and March 11, 2020, respectively). A combination of terms such as \"employee*,\" \"sleep,\" \"insomnia,\" and \"presenteeism\" was used for the search. Both randomized and non-randomized control trials were included in this systematic review.</p><p><strong>Results: </strong>Six types of sleep interventions were identified, including cognitive behavioral therapy for insomnia (CBT-I), sleep hygiene education, yoga, mindfulness, weight loss program, and changing the color temperature of fluorescent lights in the workplace. Only CBT-I improved both sleep problems and presenteeism compared with a control group. The results of this review also show that there is heterogeneity in the measurement of presenteeism.</p><p><strong>Conclusions: </strong>The results of this systematic review suggested that CBT-I could be adapted for workers with sleep problems and presenteeism. We discussed whether CBT-I improved both sleep problems and presenteeism compared with other interventions. In addition, methods for measuring presenteeism in future research are proposed.</p>","PeriodicalId":9027,"journal":{"name":"BioPsychoSocial Medicine","volume":" ","pages":"21"},"PeriodicalIF":2.1,"publicationDate":"2021-11-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8597302/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39899859","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Efficacy of rikkosan for primary burning mouth syndrome: a retrospective study.","authors":"Hiroyuki Hato,&nbsp;Ken-Ichiro Sakata,&nbsp;Jun Sato,&nbsp;Takuya Asaka,&nbsp;Noritaka Ohga,&nbsp;Yutaka Yamazaki,&nbsp;Yoshimasa Kitagawa","doi":"10.1186/s13030-021-00221-2","DOIUrl":"https://doi.org/10.1186/s13030-021-00221-2","url":null,"abstract":"<p><strong>Background: </strong>Burning mouth syndrome (BMS) is a chronic condition characterized by pain in the oral cavity. Kampo medicine is a traditional Japanese medical system that has its roots partly in ancient Chinese medicine. The purpose of this study is to evaluate the efficacy of rikkosan-a traditional Japanese herbal medicine (Kampo)-in the treatment of primary BMS.</p><p><strong>Main body: </strong>A single-center retrospective study was conducted in 32 patients who were diagnosed with primary BMS and treated with rikkosan alone through gargling (2.5 g rikkosan dissolved in 50 mL hot water) three times daily. Patients were asked to evaluate their pain using a numerical rating scale (NRS) at first visit and after 1 month. One patient had stomatitis as a side effect after gargling with rikkosan, however, no side effects were observed in other patients. Overall NRS scores decreased significantly between the first visit (7.6 ± 2.7) and the 1-month visit (5.6 ± 2.8).</p><p><strong>Conclusions: </strong>Rikkosan may be an effective treatment for primary BMS.</p>","PeriodicalId":9027,"journal":{"name":"BioPsychoSocial Medicine","volume":" ","pages":"19"},"PeriodicalIF":2.1,"publicationDate":"2021-10-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8556893/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39829217","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Background factors involved in the epidemiology of functional constipation in the Japanese population: a cross-sectional study","authors":"Sayuri Yamamoto, W. Ohashi, Y. Yamaguchi, Shunsuke Inamoto, Akira Koshino, Tomoya Sugiyama, K. Nagao, Yasuhiro Tamura, S. Izawa, M. Ebi, Jun Usami, K. Hamano, Junko Izumi, Yoshinori Wakita, Y. Funaki, N. Ogasawara, M. Sasaki, M. Maekawa, K. Kasugai","doi":"10.1186/s13030-022-00237-2","DOIUrl":"https://doi.org/10.1186/s13030-022-00237-2","url":null,"abstract":"","PeriodicalId":9027,"journal":{"name":"BioPsychoSocial Medicine","volume":"16 1","pages":""},"PeriodicalIF":2.1,"publicationDate":"2021-10-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43571567","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Relation between personality dimensions and symptomatology of depression in skin cancer patients.","authors":"M L Ramírez-de Los Santos,&nbsp;A López-Navarro,&nbsp;S Ramírez-de Los Santos,&nbsp;J M Guzmán-Flores,&nbsp;A L Pereira-Suárez,&nbsp;E I López-Pulido","doi":"10.1186/s13030-021-00220-3","DOIUrl":"https://doi.org/10.1186/s13030-021-00220-3","url":null,"abstract":"<p><strong>Background: </strong>Environmental psychological factors such as mood states can modify and trigger an organic response; depressive disorder is considered a risk factor for oncological development, leading to alterations both in the genesis and in the progression of the disease. Some authors have identified that personality relates to mood since a high score in neuroticism is associated with intense and long-lasting emotions of stress and therefore with the development of depressive behaviors. The objective of this study was to analyze the relationship between personality and depression in skin cancer patients.</p><p><strong>Methods: </strong>A total of forty-seven clinically and histopathologically diagnosed patients were scheduled for an hour-long interview, during which they provided informed consent and sociodemographic information. The psychological questionnaires applied were the revised Eysenck Personality Questionnaire and the clinical questionnaire for the diagnosis of the depressive syndrome.</p><p><strong>Results: </strong>The patient's mean age was 66.5 years (SD ± 12.4) and the majority were diagnosed with basal cell carcinoma (70.2%). The frequency of anxious/depressive symptoms was 42.5%, with an increase in depression scores in the female gender (p < 0.001). Furthermore, a difference was found in the neuroticism dimension related to gender, with higher values in women (p = 0.002). Depressive symptomatologic portraits were correlated with the dimensions of neuroticism (p < 0.001, r = 0.705), psychoticism (p = 0.003, r = 0.422) and lying (p = 0.028, r = - 0.321).</p><p><strong>Conclusions: </strong>Our results support the hypothesis that personality dimensions are related to the presence of anxiety/depressive symptomatology in patients with skin cancer, especially in the female gender. Highlighting the need for future research that delves into the implications at the psychological level, the quality of life, and the biological mechanisms that link personality and depressive symptoms in the development and evolution of skin cancer.</p>","PeriodicalId":9027,"journal":{"name":"BioPsychoSocial Medicine","volume":" ","pages":"18"},"PeriodicalIF":2.1,"publicationDate":"2021-10-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8507346/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39513709","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Health-related benefits and adverse events associated with yoga classes among participants that are healthy, in poor health, or with chronic diseases.","authors":"Takakazu Oka,&nbsp;Battuvshin Lkhagvasuren","doi":"10.1186/s13030-021-00216-z","DOIUrl":"https://doi.org/10.1186/s13030-021-00216-z","url":null,"abstract":"<p><strong>Background: </strong>Our previous study demonstrated that 42% of yoga class participants in Japan had chronic diseases requiring medication. This raises the question as to whether those with chronic diseases would benefit from practicing yoga or if they are at higher risk for specific adverse events compared to healthy individuals receiving the same instruction.</p><p><strong>Methods: </strong>To address these questions, 328 adults who started practicing yoga for the first time were asked to complete the Profile of Mood States (POMS), Perceived Stress Scale (PSS), and Medical Outcomes Study Short Form 8, standard version (SF-8™) and to record any adverse events on the first day of the yoga class and again three months later. The participants consisted of three groups: a healthy (H) group (n = 70), a poor health (PH) group (n = 117), and a chronic disease (CD) group (n = 141). The degree of subjective symptoms was also compared between the pre- and post-intervention period in the PH and CD groups.</p><p><strong>Results: </strong>Typically, yoga classes were held once a week for 60-90 min. The programs included asanas, pranayamas, meditation, isometric yoga, and sukshma vyayama. In the PH and CD groups, the POMS tension-anxiety and fatigue scores decreased and the vigor score increased significantly after the first class. Furthermore, PSS scores decreased and the SF-8™ scores increased significantly three months later. The degree of subjective symptoms such as easy fatigability, shoulder stiffness, and insomnia also decreased over three months. Individuals in these groups experienced more frequent adverse events than those in the H group. The PH and CD groups also experienced a greater variety of symptoms, including psychological ones, not reported by the H group. Adverse events were not so serious that participants stopped practicing yoga during the class. About 60% of all participants were highly satisfied with participating in yoga classes.</p><p><strong>Conclusions: </strong>If yoga classes are conducted with attention to possible adverse events, yoga practice in a yoga studio may have beneficial effects for people with functional somatic symptoms and chronic diseases, as well as healthy participants. These benefits include reductions in perceived stress and uncomfortable symptoms as well as improved mood and quality of life.</p>","PeriodicalId":9027,"journal":{"name":"BioPsychoSocial Medicine","volume":" ","pages":"17"},"PeriodicalIF":2.1,"publicationDate":"2021-10-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8499562/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39495095","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Cognitive-behavioral therapy for management of mental health and stress-related disorders: Recent advances in techniques and technologies.","authors":"Mutsuhiro Nakao,&nbsp;Kentaro Shirotsuki,&nbsp;Nagisa Sugaya","doi":"10.1186/s13030-021-00219-w","DOIUrl":"https://doi.org/10.1186/s13030-021-00219-w","url":null,"abstract":"<p><p>Cognitive-behavioral therapy (CBT) helps individuals to eliminate avoidant and safety-seeking behaviors that prevent self-correction of faulty beliefs, thereby facilitating stress management to reduce stress-related disorders and enhance mental health. The present review evaluated the effectiveness of CBT in stressful conditions among clinical and general populations, and identified recent advances in CBT-related techniques. A search of the literature for studies conducted during 1987-2021 identified 345 articles relating to biopsychosocial medicine; 154 (45%) were review articles, including 14 systemic reviews, and 53 (15%) were clinical trials including 45 randomized controlled trials. The results of several randomized controlled trials indicated that CBT was effective for a variety of mental problems (e.g., anxiety disorder, attention deficit hypersensitivity disorder, bulimia nervosa, depression, hypochondriasis), physical conditions (e.g., chronic fatigue syndrome, fibromyalgia, irritable bowel syndrome, breast cancer), and behavioral problems (e.g., antisocial behaviors, drug abuse, gambling, overweight, smoking), at least in the short term; more follow-up observations are needed to assess the long-term effects of CBT. Mental and physical problems can likely be managed effectively with online CBT or self-help CBT using a mobile app, but these should be applied with care, considering their cost-effectiveness and applicability to a given population.</p>","PeriodicalId":9027,"journal":{"name":"BioPsychoSocial Medicine","volume":" ","pages":"16"},"PeriodicalIF":2.1,"publicationDate":"2021-10-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8489050/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39480972","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effect of handholding on heart rate variability in both patients with cancer and their family caregivers: a randomized crossover study.","authors":"Hiroko Sakuma,&nbsp;Hideaki Hasuo,&nbsp;Mikihiko Fukunaga","doi":"10.1186/s13030-021-00217-y","DOIUrl":"https://doi.org/10.1186/s13030-021-00217-y","url":null,"abstract":"<p><strong>Background: </strong>Many family caregivers of patients with cancer feel guilty about self-care. A meaningful relationship with patients reduces such negative feelings and functions as self-care for family caregivers. Moreover, handholding improves autonomic functions in non-cancer patients. However, the effects of handholding on both patients with cancer and family caregivers remain unknown.</p><p><strong>Methods: </strong>We evaluated the effects of handholding on heart rate variability (HRV) in patients with cancer and their family caregivers. This randomized crossover study divided patients with cancer and their family caregivers into two trial groups: Handholding trial (the family caregiver holds the patient's hand for five minutes) and Beside trial (the family caregiver stays beside the patient without holding their hand). The study included 37 pairs of patients with cancer who received treatment in the cancer department of a university hospital in Japan and their family caregivers (n = 74). The primary end-point was the change in HRV before and during the intervention.</p><p><strong>Results: </strong>The median performance status of the patients was 3. An interaction was observed between trials in the standard deviation of the normal-to-normal interval (SDNN) of HRV for family caregivers (F = 7.669; p = 0.006), and a significant difference in time course was observed between the trials (before p = 0.351; during p = 0.003). No interaction was observed between trials in the SDNN for patients (F = 0.331; p = 0.566). Only a main effect in time course (F = 6.254; p = 0.014) was observed. SDNN increased significantly during the intervention in both trials (Handholding trial: p = 0.002, Beside trial: p = 0.049).</p><p><strong>Conclusions: </strong>Handholding improves autonomic functions of family caregivers and may function as self-care for family caregivers.</p><p><strong>Trial registration: </strong>UMIN000020557 . Registered on January 15, 2016.</p>","PeriodicalId":9027,"journal":{"name":"BioPsychoSocial Medicine","volume":" ","pages":"14"},"PeriodicalIF":2.1,"publicationDate":"2021-09-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8461863/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39444403","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A case of vestibular schwannoma with oral burning sensation: surgical complication or burning mouth syndrome?","authors":"Takayuki Suga,&nbsp;Trang T H Tu,&nbsp;Junichiro Sakamoto,&nbsp;Akira Toyofuku","doi":"10.1186/s13030-021-00215-0","DOIUrl":"https://doi.org/10.1186/s13030-021-00215-0","url":null,"abstract":"<p><strong>Background: </strong>Despite improvements in surgical techniques, the removal of vestibular schwannoma is related to some complications. Recovery from surgical complications of vestibular schwannoma is often difficult and complications sometimes lead to permanent deficits. However, treatable trigeminal symptoms may be missed in atypical cases.</p><p><strong>Case presentation: </strong>A 46-year-old woman complained about burning sensation on her tongue and maxilla for four years before her first visit to our clinic. She visited the neurosurgery department in a university hospital because her facial pain and burning sensation of her tongue were suddenly aggravated. She was diagnosed with vestibular schwannoma and tumour resection was performed. However, her oral pain persisted after surgery. Two months before the initial visit to our clinic, the oral pain became more severe than ever before. When the patient visited a psychiatrist due to a panic attack, the psychiatrist diagnosed her as having somatic symptom disorder and depression and referred her to our clinic. Based on the characteristics of the pain, she was diagnosed as burning mouth syndrome and treated for the same. Within 1.5 months, the pain and burning sensation of the tongue and maxilla almost completely remitted with low dose amitriptyline.</p><p><strong>Conclusions: </strong>Our case suggests that there are exceptional cases in which burning mouth syndrome and vestibular schwannoma occur simultaneously. Burning pain after vestibular schwannoma surgery cannot always be considered a complication of surgery.</p>","PeriodicalId":9027,"journal":{"name":"BioPsychoSocial Medicine","volume":" ","pages":"13"},"PeriodicalIF":2.1,"publicationDate":"2021-08-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8381559/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39337320","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}