{"title":"Disclosing a diagnosis of autism spectrum disorder without intellectual disability to pediatric patients in Japan in early diagnostic stages and associated factors: a cross-sectional study.","authors":"Hiroyuki Sato, Misao Fujita, Atsushi Tsuchiya, Taichi Hatta, Katsumi Mori, Eisuke Nakazawa, Yoshiyuki Takimoto, Akira Akabayashi","doi":"10.1186/s13030-022-00247-0","DOIUrl":"https://doi.org/10.1186/s13030-022-00247-0","url":null,"abstract":"<p><strong>Background: </strong>With a recent increase in the prevalence of autism spectrum disorder (ASD), an important issue has emerged in clinical practice regarding when and how patients themselves should be given explanations following a diagnosis of ASD. The clinical guidelines of the UK National Institute for Health and Care Excellence state that children diagnosed with ASD should receive an explanation about what ASD is and how it affects their development and functioning-\"if appropriate\". However, the guidelines do not provide any specifics regarding what constitutes \"appropriate\" situations METHODS: We conducted an anonymous self-administered postal questionnaire survey targeting all members of the Japanese Society for Child and Adolescent Psychiatry (n=1,995). The analysis included only physicians who had newly diagnosed pediatric patients with ASD in the past year. We imposed a limit of one year because diagnoses further back than that are difficult to recall; in other words, this would enhance the recall bias RESULTS: The recovery rate was 30.8%, and the rate of diagnosis disclosure to patients themselves without intellectual disability was 15.3%. We asked 361 physicians who responded that \"deciding on a case-by-case basis\" was the ideal way to disclose an ASD diagnosis about 20 items prioritized by physicians at the time of diagnosis disclosure and extracted three factors through exploratory factor analysis. Multiple logistic regression analysis was performed with physician attributes, awareness of ASD as a disorder or personality, and the three extracted factors as explanatory variables; diagnosis disclosure was the dependent variable. The patient age group and only one of the three factors (i.e., \"factor related to readiness to accept diagnosis\") showed a significant association with disclosure of the diagnosis to the individual. Items included in the \"factor related to readiness to accept diagnosis\" were as follows: the degree of parental understanding, relationship of the patient with their parents/physician, agreement in opinion between parents, parental consent, \"sufficient\" patient understanding, symptom stabilization, and a guarantee of sufficient time required to explain the diagnosis to the patient CONCLUSION: In clinical settings, disclosing an ASD diagnosis with the consideration of patient/parent readiness toward accepting the diagnosis could help to guide physicians in determining an ideal timing for disclosure. Future studies are needed to establish detailed and concrete guidelines regarding disclosure of an ASD diagnosis to patients.</p>","PeriodicalId":9027,"journal":{"name":"BioPsychoSocial Medicine","volume":" ","pages":"18"},"PeriodicalIF":2.1,"publicationDate":"2022-08-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9391641/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40711207","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Correlation of catecholamine content and clinical influencing factors in depression among psoriasis patients: a case-control study.","authors":"Si-Qi Long, Jing Fang, Hui-Ling Shu, Deng-Mei Xia, Zheng-Qun Wang, Wen-Yao Mi, Xue-Li Zhang, Chang-Qiang Li","doi":"10.1186/s13030-022-00245-2","DOIUrl":"https://doi.org/10.1186/s13030-022-00245-2","url":null,"abstract":"<p><strong>Objective: </strong>Our study sought to investigate the clinical influencing factors of psoriasis patients with depression, and analyze whether the content of monoamine neurotransmitters in plasma was correlated with depression incidence among psoriasis patients.</p><p><strong>Methods: </strong>Ninety patients with psoriasis and 40 healthy volunteers (aged from18 to 60) were recruited and interviewed with a piloted questionnaire in both groups to obtain relevant information. The catecholamine in plasma from the two groups was analyzed by radioimmunoassay. The data were analyzed by SPSS statistical software.</p><p><strong>Results: </strong>The mean Hamilton Depression Scale (HAMD) and mean Athens Insomnia Scale (AIS) scores of the psoriasis patients were higher than the control group. Dopamine content in the plasma was lower (comparing psoriasis patients without depression and the control group, and was negatively correlated with HAMD, AIS, and Psoriasis Area and Severity Index (PASI) scores in the psoriasis patients with depression. There was no significant difference in the epinephrine and norepinephrine contents in all groups. PASI scores were positively correlated with HAMD scores in psoriasis patients. The low dopamine content, Dermatology Life Quality Index, and high PASI scores were the risk factors for depression among the psoriasis patients.</p><p><strong>Conclusion: </strong>Psoriasis patients have a significantly higher risk of depression than healthy people, and higher PASI scores were linked to a higher incidence of depression. The dopamine levels of patients were influenced by both psoriasis and depression. The risk factors for depression in psoriasis patients are low dopamine levels in the plasma, severe skin lesions, and lower quality of life.</p>","PeriodicalId":9027,"journal":{"name":"BioPsychoSocial Medicine","volume":" ","pages":"17"},"PeriodicalIF":2.1,"publicationDate":"2022-08-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9364537/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40598217","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Ethyl loflazepate as a treatment for patients with idiopathic and psychogenic taste disorder.","authors":"Ken-Ichiro Sakata, Hiroyuki Hato, Jun Sato, Takashi Iori, Noritaka Ohga, Haruhisa Watanabe, Yutaka Yamazaki, Yoshimasa Kitagawa","doi":"10.1186/s13030-022-00246-1","DOIUrl":"https://doi.org/10.1186/s13030-022-00246-1","url":null,"abstract":"<p><strong>Background: </strong>Ethyl loflazepate (EL) is a benzodiazepine derivative that has been reported to activate the gustatory cortex. Our department routinely uses EL as a first-line treatment for idiopathic and psychogenic taste disorders, although little has been reported in the literature with respect to patient outcomes, so we conducted a retrospective study examining its safety and efficacy.</p><p><strong>Methods: </strong>Between 2008 and 2020, 49 patients (14 males and 35 females; mean age, 62.1 years) were diagnosed with taste disorders and received EL as their only treatment for > 14 days. Severity of taste disorder was evaluated using the paper disc method by Sakai et al., and treatment efficacy was evaluated using the Visual Analog Scale, wherein patients gave subjective ratings for their symptoms (reductions by > 50% after administration of EL for 4 weeks were defined as improvements).</p><p><strong>Results: </strong>Results showed that the improvement rates for patients with idiopathic and psychogenic taste disorders were 55 and 70%, respectively. Additionally, the majority (78%) improved within 2 weeks, and side effects were mild (seven cases with drowsiness and one case with dizziness).</p><p><strong>Conclusions: </strong>We conclude that EL is an appropriate first-line medication for patients with idiopathic and psychogenic taste disorders.</p>","PeriodicalId":9027,"journal":{"name":"BioPsychoSocial Medicine","volume":" ","pages":"16"},"PeriodicalIF":2.1,"publicationDate":"2022-08-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9358076/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40593695","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Validity and reliability of the Japanese versions of cognitive and behavioral scales for irritable bowel syndrome.","authors":"Nagisa Sugaya, Yoshitoshi Tomita, Misako Funaba, Hiroshi Iida, Kentaro Shirotsuki, Fumiyuki Chin Gardner, Toshinari Odawara, Tetsuya Ando, Masahiko Inamori","doi":"10.1186/s13030-022-00244-3","DOIUrl":"https://doi.org/10.1186/s13030-022-00244-3","url":null,"abstract":"<p><strong>Background: </strong>The Cognitive Scale for Functional Bowel Disorders (CS-FBD) and Irritable Bowel Syndrome-Behavioral Responses Questionnaire (IBS-BRQ) are a useful measures to assess cognitive-behavioral aspects in individuals with IBS. This study aimed to confirm the reliability and validity of the Japanese versions of the CS-FBD (CS-FBD-J) and IBS-BRQ (IBS-BRQ-J).</p><p><strong>Methods: </strong>Participants comprised 192 students and 22 outpatients diagnosed with irritable bowel syndrome (IBS). There were 76 students who met the diagnostic criteria for IBS and two students who received treatment for IBS. Participants completed questionnaires containing the CS-FBD-J, IBS Severity Index (IBS-SI), Visceral Sensitivity Index (VSI), 24-item Dysfunctional Attitudes Scale (DAS-24), Hospital Anxiety and Depression Scale (HADS), and Social Adaptation Self-evaluation Scale (SASS).</p><p><strong>Results: </strong>Our exploratory factor analysis revealed that the CS-FBD-J had a unidimensional factor structure and that the factor loadings for two of the 25 items were less than 0.4. The IBS-BRQ-J had a two-factor structure, and the factor loadings for eight of the 26 items were less than 0.4. The confirmatory factor analysis for the 18-item version of IBS-BRQ-J showed that the model fit indices were not sufficient. The CS-FBD-J and IBS-BRQ-J had significant, moderate correlations with the IBS-SI and VSI in the IBS and control groups. Correlation between the DAS-24 and the CS-FBD-J was not significant. The CS-FBD-J and IBS-BRQ-J were significantly correlated to the HADS and SASS (IBS-BRQ-J) only in the IBS group. The scores of CS-FBD-J and IBS-BRQ-J showed significant group differences between the IBS patient group, non-patient IBS group, and control group. The internal consistencies of the CS-FBD-J and IBS-BRQ-J were high. The item-total correlation analysis for the CS-FBD-J and IBS-BRQ-J showed that the correlations between each item and the total score were significant.</p><p><strong>Conclusion: </strong>This study confirmed the reliability and validity of the 23-item version of the CS-FBS-J and the 18-item version of the IBS-BRQ-J with the deletion of items with low factor loadings. Regarding the IBS-BRQ-J, two factor structures were confirmed (factor 1: behavior obsessed with abdominal symptoms, factor 2: avoidance of abdominal symptoms and associated difficulties) although the model fit of the structure needs further study.</p>","PeriodicalId":9027,"journal":{"name":"BioPsychoSocial Medicine","volume":" ","pages":"15"},"PeriodicalIF":2.1,"publicationDate":"2022-07-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9308329/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40628519","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Effects of practicing yoga on alexisomia: an open-label trial.","authors":"Takakazu Oka, Battuvshin Lkhagvasuren","doi":"10.1186/s13030-022-00243-4","DOIUrl":"https://doi.org/10.1186/s13030-022-00243-4","url":null,"abstract":"<p><strong>Background: </strong>Alexisomia refers to difficulties in the awareness and expression of somatic feelings. This idea was proposed by Dr. Yujiro Ikemi as a characteristic observed in patients with psychosomatic diseases and is based on his observations that patients with psychosomatic diseases have difficulty in the awareness and expression of not only their emotions, i.e., alexithymia, but also somatic feelings and sensations, i.e., alexisomia. He also proposed that treating alexisomia is important in the treatment of psychosomatic diseases and that yoga might help improve alexisomia. However, no study has investigated if yoga actually affects alexisomia. This open-label pilot study investigated whether practicing yoga in a class results in change in patients with alexisomia and alexithymia.</p><p><strong>Methods: </strong>The Shitsu-taikan-sho Scale (STSS) and the Toronto Alexithymia Scale (TAS-20) were administered to 305 participants, including 64 healthy participants, 111 participants who had subjective symptoms without abnormal findings, and 130 participants with chronic diseases. Participants were tested before and 3 months after attending yoga classes.</p><p><strong>Results: </strong>Yoga practice reduced the STSS and the TAS-20 difficulty in identifying feelings (DIF) subscale scores. Multiple linear regression indicated that a reduction in the TAS-20 DIF subscale scores predicted a decrease in the STSS score, whereas reductions in the STSS difficulty in identifying bodily feelings (DIB) and the lack of health management based on bodily feelings (LHM) subscale scores predicted a decrease in the TAS-20 scores.</p><p><strong>Conclusion: </strong>We found that regular yoga practice improves alexisomia. Yoga-induced improvement of alexisomia may be mediated, at least in part, by an improvement of DIF in alexithymia. Yoga would be a promising therapeutic approach to improve alexisomia.</p>","PeriodicalId":9027,"journal":{"name":"BioPsychoSocial Medicine","volume":"16 1","pages":"14"},"PeriodicalIF":2.1,"publicationDate":"2022-06-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9166595/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10307758","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Chihiro Morishita, Takeshi Inoue, Mina Honyashiki, Miki Ono, Y. Iwata, Hajime Tanabe, I. Kusumi, Jiro Masuya
{"title":"Roles of childhood maltreatment, personality traits, and life stress in the prediction of severe premenstrual symptoms","authors":"Chihiro Morishita, Takeshi Inoue, Mina Honyashiki, Miki Ono, Y. Iwata, Hajime Tanabe, I. Kusumi, Jiro Masuya","doi":"10.1186/s13030-022-00240-7","DOIUrl":"https://doi.org/10.1186/s13030-022-00240-7","url":null,"abstract":"","PeriodicalId":9027,"journal":{"name":"BioPsychoSocial Medicine","volume":" ","pages":""},"PeriodicalIF":2.1,"publicationDate":"2022-04-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48972520","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Tomoe Nishihara, A. Ohashi, Yuko Nakashima, T. Yamashita, Kazutoshi Hiyama, Mika Kuroiwa
{"title":"Compassion fatigue in a health care worker treating COVID-19 patients: a case report","authors":"Tomoe Nishihara, A. Ohashi, Yuko Nakashima, T. Yamashita, Kazutoshi Hiyama, Mika Kuroiwa","doi":"10.1186/s13030-022-00239-0","DOIUrl":"https://doi.org/10.1186/s13030-022-00239-0","url":null,"abstract":"","PeriodicalId":9027,"journal":{"name":"BioPsychoSocial Medicine","volume":" ","pages":""},"PeriodicalIF":2.1,"publicationDate":"2022-04-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44136183","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"The patterns of acceptance, mindfulness, and values for Japanese patients with type 2 diabetes mellitus: a web-based survey","authors":"J. Saito, H. Kumano","doi":"10.1186/s13030-022-00236-3","DOIUrl":"https://doi.org/10.1186/s13030-022-00236-3","url":null,"abstract":"","PeriodicalId":9027,"journal":{"name":"BioPsychoSocial Medicine","volume":" ","pages":""},"PeriodicalIF":2.1,"publicationDate":"2022-03-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49668101","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Y. Ishizaki, Yoshitoki Yanagimoto, Yuri Fujii, Mana Yamamoto, Kazunari Kaneko
{"title":"Psychogenic fever and postural tachycardia syndrome among school-aged children and adolescents with fever of unknown origin","authors":"Y. Ishizaki, Yoshitoki Yanagimoto, Yuri Fujii, Mana Yamamoto, Kazunari Kaneko","doi":"10.1186/s13030-022-00238-1","DOIUrl":"https://doi.org/10.1186/s13030-022-00238-1","url":null,"abstract":"","PeriodicalId":9027,"journal":{"name":"BioPsychoSocial Medicine","volume":" ","pages":""},"PeriodicalIF":2.1,"publicationDate":"2022-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46003737","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}