{"title":"Efficacy of Intraoperative Anterior Segment Optical Coherence Tomography during Descemet's Stripping Automated Endothelial Keratoplasty.","authors":"Akio Miyakoshi, Hironori Ozaki, Mitsuya Otsuka, Atsushi Hayashi","doi":"10.1155/2014/562062","DOIUrl":"https://doi.org/10.1155/2014/562062","url":null,"abstract":"<p><p>Purpose. To examine the graft-host interface during Descemet's stripping automated endothelial keratoplasty (DSAEK) surgery with optical coherence tomography (OCT). Design. Prospective, interventional case series. Patients and Methods. Eight patients who underwent a DSAEK were included. A handheld OCT was used intraoperatively to examine the presence of interface fluid between the host cornea and the graft. Results. In 3 patients, no interface fluid was detected between the host cornea and the graft after the graft was attached by air injection. In 4 patients, interface fluid was detected after the graft was attached by air injection. The remaining interface fluid was drained through corneal stab incisions. One patient required a second surgery because the first surgery failed due to persistence of the interface fluid. All patients showed a complete attachment of the graft at one month after the DSAEK surgery. Conclusion. A handheld OCT is useful to detect the interface fluid between the host cornea and the graft during a DSAEK. </p>","PeriodicalId":90193,"journal":{"name":"ISRN ophthalmology","volume":"2014 ","pages":"562062"},"PeriodicalIF":0.0,"publicationDate":"2014-02-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1155/2014/562062","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"32179815","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
ISRN ophthalmologyPub Date : 2014-01-22eCollection Date: 2014-01-01DOI: 10.1155/2014/417603
Andre Grixti, Evangelia Papavasileiou, Dominic Cortis, Balakrishna Vineeth Kumar, Som Prasad
{"title":"Phacoemulsification surgery in eyes with neovascular age-related macular degeneration.","authors":"Andre Grixti, Evangelia Papavasileiou, Dominic Cortis, Balakrishna Vineeth Kumar, Som Prasad","doi":"10.1155/2014/417603","DOIUrl":"https://doi.org/10.1155/2014/417603","url":null,"abstract":"<p><p>Purpose. To evaluate the visual outcomes and effect of phacoemulsification surgery on the progression of neovascular age-related macular degeneration (AMD). Methods. Retrospective, noncomparative, and interventional case series. Thirty eyes from 29 subjects with neovascular AMD treated with intravitreal antivascular endothelial growth factor (VEGF) injections who underwent phacoemulsification and had a postsurgery follow-up of 6 months were included. LogMAR best corrected visual acuity (BCVA) was assessed preoperatively; 1 month, 3 months, and 6 months postoperatively; and finally at the last visit. The frequency of anti-VEGF therapy, calculated as the number of intravitreal injections per month, and central macular thickness (CMT) before and after cataract surgery were determined. Results. Median (range) logMAR BCVA was 0.69 (0.16 to 1.32) preoperatively; 0.55 (-0.04 to 1.32) at 1 month, 0.52 (-0.1 to 1.32) at 3 months, and 0.50 (0.0 to 1.32) at 6 months postoperatively; and 0.6 (0.0 to 1.4) at final visit (P = 0.0011). There was no difference in the frequency of anti-VEGF injections between the immediate 6 months before and after phacoemulsification, which was equal to 0.1667 injections per month (P = 0.6377). Median CMT measured 203 μ m preoperatively, which temporarily increased to 238 μ m at 1 month after surgery (P = 0.0093) and then spontaneously returned to baseline, measuring 212.5 μ m at 3 months postoperatively (P = 0.3811). Conclusion. Phacoemulsification surgery significantly improved vision in patients with neovascular AMD, with no increased need for anti-VEGF injections to keep the macula dry postoperatively. </p>","PeriodicalId":90193,"journal":{"name":"ISRN ophthalmology","volume":"2014 ","pages":"417603"},"PeriodicalIF":0.0,"publicationDate":"2014-01-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1155/2014/417603","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"32252886","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
ISRN ophthalmologyPub Date : 2013-12-19eCollection Date: 2013-01-01DOI: 10.1155/2013/141279
Abdullah Ozkaya, Ugur Celik, Zeynep Alkin, Miray Faiz Turan, Ahmet Taylan Yazici, Ahmet Demirok
{"title":"Comparison between Intravitreal Triamcinolone with Grid Laser Photocoagulation versus Bevacizumab with Grid Laser Photocoagulation Combinations for Branch Retinal Vein Occlusion.","authors":"Abdullah Ozkaya, Ugur Celik, Zeynep Alkin, Miray Faiz Turan, Ahmet Taylan Yazici, Ahmet Demirok","doi":"10.1155/2013/141279","DOIUrl":"https://doi.org/10.1155/2013/141279","url":null,"abstract":"<p><p>Purpose. To compare the efficacy of intravitreal triamcinolone (IVT) and intravitreal bevacizumab (IVB), both combined with grid laser photocoagulation (GLP) for macular edema (ME) secondary to branch retinal vein occlusion (BRVO). Methods. Retrospective, comparative study. The newly diagnosed patients with ME secondary to BRVO who were treated with IVT and GLP or IVB and GLP were included. The main outcome measures were changed in the best corrected visual acuity (BCVA) and central retinal thickness (CRT) from the baseline to month 24. Results. Ninety-nine eyes of 99 patients were included. The change in BCVA was not statistically different in any time points between the two groups (P > 0.05, for all). The change in CRT was not statistically different in any time points between the two groups (P > 0.05, for all). The mean number of injections at month 24 was 2.38 ± 1.06 in the IVT+GLP group and 4.17 ± 1.30 in the IVB+GLP group (P = 0.0001). The need for cataract surgery (P = 0.01) and secondary glaucoma (P = 0.03) occurrence were more common in IVT group. Conclusion. Both treatment modalities were effective in the treatment of ME secondary to BRVO. The number of injections was significantly lower in the IVT group than in the IVB group; however cataract and secondary glaucoma were more frequent in the IVT+GLP group than in the IVB+GLP group. </p>","PeriodicalId":90193,"journal":{"name":"ISRN ophthalmology","volume":"2013 ","pages":"141279"},"PeriodicalIF":0.0,"publicationDate":"2013-12-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1155/2013/141279","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"32141107","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
ISRN ophthalmologyPub Date : 2013-10-10eCollection Date: 2013-01-01DOI: 10.1155/2013/264604
Fiona J Rowe, David Wright, Darren Brand, Carole Jackson, Shirley Harrison, Tallat Maan, Claire Scott, Linda Vogwell, Sarah Peel, Nicola Akerman, Caroline Dodridge, Claire Howard, Tracey Shipman, Una Sperring, Sonia Macdiarmid, Cicely Freeman
{"title":"Profile of Gaze Dysfunction following Cerebrovascular Accident.","authors":"Fiona J Rowe, David Wright, Darren Brand, Carole Jackson, Shirley Harrison, Tallat Maan, Claire Scott, Linda Vogwell, Sarah Peel, Nicola Akerman, Caroline Dodridge, Claire Howard, Tracey Shipman, Una Sperring, Sonia Macdiarmid, Cicely Freeman","doi":"10.1155/2013/264604","DOIUrl":"https://doi.org/10.1155/2013/264604","url":null,"abstract":"<p><p>Aim. To evaluate the profile of ocular gaze abnormalities occurring following stroke. Methods. Prospective multicentre cohort trial. Standardised referral and investigation protocol including assessment of visual acuity, ocular alignment and motility, visual field, and visual perception. Results. 915 patients recruited: mean age 69.18 years (SD 14.19). 498 patients (54%) were diagnosed with ocular motility abnormalities. 207 patients had gaze abnormalities including impaired gaze holding (46), complete gaze palsy (23), horizontal gaze palsy (16), vertical gaze palsy (17), Parinaud's syndrome (8), INO (20), one and half syndrome (3), saccadic palsy (28), and smooth pursuit palsy (46). These were isolated impairments in 50% of cases and in association with other ocular abnormalities in 50% including impaired convergence, nystagmus, and lid or pupil abnormalities. Areas of brain stroke were frequently the cerebellum, brainstem, and diencephalic areas. Strokes causing gaze dysfunction also involved cortical areas including occipital, parietal, and temporal lobes. Symptoms of diplopia and blurred vision were present in 35%. 37 patients were discharged, 29 referred, and 141 offered review appointments. 107 reviewed patients showed full recovery (4%), partial improvement (66%), and static gaze dysfunction (30%). Conclusions. Gaze dysfunction is common following stroke. Approximately one-third of patients complain of visual symptoms, two thirds show some improvement in ocular motility. </p>","PeriodicalId":90193,"journal":{"name":"ISRN ophthalmology","volume":"2013 ","pages":"264604"},"PeriodicalIF":0.0,"publicationDate":"2013-10-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1155/2013/264604","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"32143865","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
ISRN ophthalmologyPub Date : 2013-10-03eCollection Date: 2013-01-01DOI: 10.1155/2013/549240
Tulin Aras Ogreden, Zeynep Alkin, Abdullah Ozkaya, Halil Ibrahim Demirkale, Irfan Perente, Cengiz Aras
{"title":"Evaluation of contrast sensitivity after single intravitreal triamcinolone injection for macular edema secondary to branch retinal vein occlusion.","authors":"Tulin Aras Ogreden, Zeynep Alkin, Abdullah Ozkaya, Halil Ibrahim Demirkale, Irfan Perente, Cengiz Aras","doi":"10.1155/2013/549240","DOIUrl":"https://doi.org/10.1155/2013/549240","url":null,"abstract":"<p><p>Purpose. To evaluate visual acuity (VA), contrast sensitivity (CS), and central retinal thickness (CRT) after intravitreal triamcinolone acetonide (IVT) injection for macular edema secondary to branch retinal vein occlusion (BRVO). Methods. In this prospective study, a total of 21 eyes of 21 patients were included. VA, CS, and CRT were assessed at baseline and at 1, 3, and 6 months after a single IVT injection. Results. Mean age was 64.57 ± 8.34 years. The mean baseline VA (LogMAR) increased from 1.11 ± 0.63 to 0.55 ± 0.39 (P < 0.001), 0.60 ± 0.40 (P < 0.001), and 0.78 ± 0.39 (P = 0.07) at 1, 3, and 6 months, respectively. The mean baseline CS (log CS) at 1 meter improved from 0.66 ± 0.49 to 1.11 ± 0.32 (P < 0.001), 0.99 ± 0.38 (P < 0.001), and 0.72 ± 0.37 (P = 0.8) at 1, 3, and 6 months, respectively. The mean baseline CS (log CS) at 3 meters improved from 0.34 ± 0.41 to 0.74 ± 0.41 (P < 0.001), 0.64 ± 0.44 (P = 0.036), and 0.46 ± 0.49 (P = 0.8) at 1, 3, and 6 months, respectively. The mean baseline CRT decreased from 511 ± 146 μm to 242 ± 119 μm, 277 ± 131 μm, and 402 ± 166 μm at 1, 3, and 6 months after IVT (P < 0.001 for each). Conclusion. Single IVT injection improved VA and CS and reduced CRT at 1 and 3 months of treatment. VA and CS returned to baseline levels at 6 months. </p>","PeriodicalId":90193,"journal":{"name":"ISRN ophthalmology","volume":"2013 ","pages":"549240"},"PeriodicalIF":0.0,"publicationDate":"2013-10-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1155/2013/549240","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"32148059","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
ISRN ophthalmologyPub Date : 2013-09-28eCollection Date: 2013-01-01DOI: 10.1155/2013/815840
Maya Fe Ng-Darjuan, Raymond P Evangelista, Archimedes Lee D Agahan
{"title":"Photorefractive Keratectomy with Adjunctive Mitomycin C for Residual Error after Laser-Assisted In Situ Keratomileusis Using the Pulzar 213 nm Solid-State Laser: Early Results.","authors":"Maya Fe Ng-Darjuan, Raymond P Evangelista, Archimedes Lee D Agahan","doi":"10.1155/2013/815840","DOIUrl":"https://doi.org/10.1155/2013/815840","url":null,"abstract":"<p><p>Purpose. To evaluate the accuracy, efficacy, stability, and safety of photorefractive keratectomy (PRK) enhancement using the Pulzar 213 nm solid-state laser (SSL) with adjunctive Mitomycin C in eyes previously treated with laser assisted in situ keratomileusis (LASIK) with residual error of refraction. Methods. This is a prospective noncomparative case series of 16 eyes of 12 patients who underwent PRK for residual refractive error after primary LASIK. Mitomycin C 0.02% was used after the PRK to prevent haze formation. Outcomes measured were pre- and postoperative manifest refraction spherical equivalent (MRSE), uncorrected (UDVA) and best-corrected distance visual acuity (CDVA), and slit lamp evidence of corneal complications. Results. The mean UDVA improved from 20/70 preoperatively to 20/30 postoperatively. The average gain in lines for the UDVA was 2.38. After six months of followup, the postoperative MRSE within 0.50 D in 56% (9) of eyes and 94% (15) eyes were within 1.0 diopters of the intended correction. No eyes developed haze all throughout the study. Conclusion. PRK enhancement with adjunctive use of Mitomycin C for the correction of residual error of refraction after LASIK using the Pulzar 213 nm solid-state laser is an accurate, effective, and safe procedure. </p>","PeriodicalId":90193,"journal":{"name":"ISRN ophthalmology","volume":"2013 ","pages":"815840"},"PeriodicalIF":0.0,"publicationDate":"2013-09-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1155/2013/815840","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"32141110","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
ISRN ophthalmologyPub Date : 2013-09-19eCollection Date: 2013-01-01DOI: 10.1155/2013/814814
Peter Heiduschka, Daniel Renninger, Dietmar Fischer, Adrienne Müller, Sabine Hofmeister, Ulrich Schraermeyer
{"title":"Lens Injury Has a Protective Effect on Photoreceptors in the RCS Rat.","authors":"Peter Heiduschka, Daniel Renninger, Dietmar Fischer, Adrienne Müller, Sabine Hofmeister, Ulrich Schraermeyer","doi":"10.1155/2013/814814","DOIUrl":"https://doi.org/10.1155/2013/814814","url":null,"abstract":"<p><p>Lens injury induced activation of retinal glia, and subsequent release of ciliary neurotrophic factor (CNTF) and leukaemia inhibitory factor (LIF) potently protect axotomised retinal ganglion cells from apoptosis and promotes axon regeneration in the injured optic nerve. The goal of the current study was to investigate if similar effects may also be applicable to rescue photoreceptors from degeneration in a model of retinitis pigmentosa. Lens injury was performed in the Royal College of Surgeons (RCS) rats at the age of one month. The survival of photoreceptors was evaluated histologically, and retinal function was analysed by electroretinography (ERG). Expression of CNTF was also analysed. Lens injury significantly enhanced the survival of photoreceptors 1 month after surgery compared to untreated controls, which was associated with an enhanced ERG response. In addition, lens injury significantly protected photoreceptors from degeneration in the contralateral eye, although to a much lesser extent. We could show that lens injury is sufficient to transiently delay the degeneration of photoreceptors in the RCS rat. The observed neuroprotective effects may be at least partially mediated by an upregulation of CNTF expression seen after lens injury. </p>","PeriodicalId":90193,"journal":{"name":"ISRN ophthalmology","volume":"2013 ","pages":"814814"},"PeriodicalIF":0.0,"publicationDate":"2013-09-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1155/2013/814814","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"32144324","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
ISRN ophthalmologyPub Date : 2013-09-19eCollection Date: 2013-01-01DOI: 10.1155/2013/353209
Justin T Wilkinson, Amanda B Richards, Dongseok Choi, Joseph E Robertson, Christina J Flaxel
{"title":"Incidence of retinal detachment after fellow-performed primary pars plana vitrectomy.","authors":"Justin T Wilkinson, Amanda B Richards, Dongseok Choi, Joseph E Robertson, Christina J Flaxel","doi":"10.1155/2013/353209","DOIUrl":"https://doi.org/10.1155/2013/353209","url":null,"abstract":"<p><p>Background. Primary pars plana vitrectomy (PPV) is often performed by vitreoretinal fellows. We aimed to evaluate the incidence of retinal breaks and detachments (RD) after fellow-performed PPV. Methods. We reviewed 119 consecutive cases of standard 3-port primary PPVs on 115 patients at a teaching institution from 2003 to 2006. In all cases, the primary surgeon was a vitreoretinal fellow. Patients with previous RD were excluded. Cases were reviewed for postoperative retinal detachments, and all patients were followed for up to 1 year. Results. Intraoperative retinal breaks occurred in 5 of 119 eyes (4.2%). One break was associated with sclerotomy and 4 were not. Postoperative RD occurred in 8 of 119 eyes (6.7%). Two RDs were sclerotomy related, 5 were not, and 1 was of indeterminate origin. Conclusions. Incidence of retinal breaks and RD following primary PPV by vitreoretinal fellows is low and comparable to that of fellowship-trained surgeons. </p>","PeriodicalId":90193,"journal":{"name":"ISRN ophthalmology","volume":"2013 ","pages":"353209"},"PeriodicalIF":0.0,"publicationDate":"2013-09-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1155/2013/353209","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"32148445","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
ISRN ophthalmologyPub Date : 2013-09-12eCollection Date: 2013-01-01DOI: 10.1155/2013/210565
Maria L Salvetat, Marco Zeppieri, Flavia Miani, Paolo Brusini
{"title":"Postkeratoplasty Anterior and Posterior Corneal Surface Wavefront Analysis: Descemet's Stripping Automated Endothelial Keratoplasty versus Penetrating Keratoplasty.","authors":"Maria L Salvetat, Marco Zeppieri, Flavia Miani, Paolo Brusini","doi":"10.1155/2013/210565","DOIUrl":"https://doi.org/10.1155/2013/210565","url":null,"abstract":"<p><p>Purpose. To compare the higher-order aberrations (HOAs) due to the anterior and posterior corneal surfaces in patients that underwent either Descemet-stripping-automated-endothelial-keratoplasty (DSAEK) or penetrating keratoplasty (PK) for endothelial dysfunction and age-matched controls. Methods. This retrospective, observational, case series included 28 patients after PK, 30 patients after DSAEK, and 30 healthy controls. A Scheimpflug imaging system was used to assess the HOAs due to the anterior and posterior corneal surfaces at 4 mm and 6 mm optical zones. Total, 3rd and 4th order HOAs were considered. Intra- and intergroup differences were assessed using the Friedman and the Kruskal-Wallis tests, respectively; paired comparisons were performed using Duncan's multiple range test. Results. Total, 3rd and 4th order HOAs due to both corneal surfaces at 4 mm and 6 mm optical zones were significantly higher in the PK group, intermediate in the DSAEK group, and lower in controls (P < 0.05). The most important HOAs components in both PK and DSAEK groups were trefoil and coma from the anterior corneal surface (P < 0.05) and trefoil from the posterior corneal surface (P < 0.05). Conclusions. The optical quality of both corneal surfaces appeared significantly higher after DSAEK than after PK, which can increase the postoperative patient's quality of vision and satisfaction. </p>","PeriodicalId":90193,"journal":{"name":"ISRN ophthalmology","volume":"2013 ","pages":"210565"},"PeriodicalIF":0.0,"publicationDate":"2013-09-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1155/2013/210565","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"32143863","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Preoperative and postoperative optical coherence tomography findings in patients with rhegmatogenous retinal detachment involving the macular region.","authors":"Asaki Matsui, Hiroshi Toshida, Rio Honda, Takahiko Seto, Toshihiko Ohta, Akira Murakami","doi":"10.1155/2013/426867","DOIUrl":"https://doi.org/10.1155/2013/426867","url":null,"abstract":"<p><p>Purpose. To evaluate morphologic changes of the macula, we observed eyes with rhegmatogenous retinal detachment (RRD) involving the macular region by optical coherence tomography (OCT). Subjects and Methods. We studied 26 eyes with RRD before and after surgery, assessing visual acuity, the height of retinal detachment at the fovea (HRD), and morphologic changes of the macular region. The interval between the onset and surgery was also determined. We examined the external limiting membrane (ELM) after surgery and the continuity of the inner segment-outer segment junction (IS/OS junction) of the photoreceptor layer. Results. Impairment of visual acuity was observed when HRD was over 1,000 μ m, when there was outer nuclear layer edema before surgery, and when there was IS/OS junction disruption 3 months after surgery. However, 67% of eyes with a continuous ELM and IS/OS junction disruption 3 months after surgery eventually showed restoration of the continuity of IS/OS junction at 6 months. Conclusions. Impairment of visual acuity was observed in eyes with HRD >1,000 μ m, preoperative outer nuclear layer edema, and IS/OS junction disruption 3 months postoperatively. It is suggested that continuity of ELM might affect restoration of IS/OS junction after surgery for retinal detachment. </p>","PeriodicalId":90193,"journal":{"name":"ISRN ophthalmology","volume":"2013 ","pages":"426867"},"PeriodicalIF":0.0,"publicationDate":"2013-09-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1155/2013/426867","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"32148448","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}