Blood PressurePub Date : 2026-12-01Epub Date: 2026-02-13DOI: 10.1080/08037051.2026.2624257
Heloísa Ribeiro, Eduardo Matos Vilela, Fernando Martos Gonçalves, Cristina Gavina, Rosa de Pinho
{"title":"A consensus statement from the Portuguese Society of Hypertension and the Portuguese Society of Cardiology for bridging the 2023-2025 hypertension Guidelines in clinical practice.","authors":"Heloísa Ribeiro, Eduardo Matos Vilela, Fernando Martos Gonçalves, Cristina Gavina, Rosa de Pinho","doi":"10.1080/08037051.2026.2624257","DOIUrl":"10.1080/08037051.2026.2624257","url":null,"abstract":"<p><strong>Background: </strong>Effective management of arterial hypertension remains a major global health priority. In the need to improve real-world implementation of best practices, three international organisations have released independent clinical practice guidelines: the European Society of Hypertension (ESH, 2023), the European Society of Cardiology (ESC, 2024) and the American College of Cardiology/American Heart Association (AHA/ACC, 2025).<sup>1</sup>.</p><p><strong>Aim and methods: </strong>This society-endorsed consensus document, jointly developed by the Portuguese Society of Hypertension and the Portuguese Society of Cardiology, aims to harmonise partially divergent hypertension guidelines into applicable recommendations. It provides a pragmatic comparative synthesis of the 2023-2025 guidelines, structured according to the M.A.P.E. framework (Measure, Assess, Prescribe, Evaluate), to support decision-making in clinical practice.</p><p><strong>Results: </strong>Across European guidelines, there is a strong alignment in the definition of hypertension (systolic BP ≥140 mmHg and/or diastolic BP ≥90 mmHg), CV risk stratification, lifestyle interventions, and first-line use of combination therapy of two drugs out of four. Divergences arise in BP classification systems, initiation thresholds, dosing strategies and target BP goals. The 2025 AHA/ACC Guidelines differ by adopting lower diagnostic and treatment thresholds (≥130/80 mmHg) and early pharmacological intervention based on individual CV risk. This consensus acknowledges differences and supports a risk-based approach grounded in randomised trial evidence, feasibility in routine clinical practice, and patient safety, recognising office BP as the basis for treatment decisions.</p><p><strong>Conclusions: </strong>This consensus aims to reduce clinical uncertainty and optimise hypertension management in real-world practice providing clear and evidence-informed clinical recommendations.</p>","PeriodicalId":9000,"journal":{"name":"Blood Pressure","volume":"35 1","pages":"2624257"},"PeriodicalIF":2.3,"publicationDate":"2026-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146177628","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Blood PressurePub Date : 2026-12-01Epub Date: 2026-04-04DOI: 10.1080/08037051.2026.2653312
Konstantinos Sideris, Ioannis Andrikou, Konstantinos Tsioufis
{"title":"Reassessing blood pressure control: the role of long-term blood pressure variability and time in target range.","authors":"Konstantinos Sideris, Ioannis Andrikou, Konstantinos Tsioufis","doi":"10.1080/08037051.2026.2653312","DOIUrl":"10.1080/08037051.2026.2653312","url":null,"abstract":"<p><strong>Purpose: </strong>This review summarizes current evidence on visit-to-visit blood pressure variability (BPV) and blood pressure time in target range (TTR) as complementary measures of blood pressure (BP) control, and to evaluate their ability to predict cardiovascular (CV) risk beyond mean BP values in hypertensive populations.</p><p><strong>Materials and methods: </strong>We performed a narrative review of observational studies, post-hoc analyses of randomised clinical trials, and population-based cohorts evaluating long-term systolic BPV and TTR in relation to adverse CV outcomes. Evidence comparing BPV and TTR, including studies assessing their combined prognostic value, was synthesised to examine their relative and complementary roles in CV risk prediction beyond mean BP levels.</p><p><strong>Results: </strong>Long-term systolic visit-to-visit BPV has been consistently associated with increased risks of CV morbidity, mortality, stroke, and cognitive decline, independent of mean BP. Similarly, higher systolic TTR has been associated with lower risks of all-cause mortality, CV events, heart failure, and composite CV outcomes across diverse populations and BP monitoring strategies. Studies evaluating both indices concurrently demonstrate that BPV and TTR provide independent and complementary prognostic information, with patients exhibiting low TTR and high BPV experiencing the highest CV risk. While TTR reflects the duration and stability of BP control within target ranges, BPV captures the magnitude of BP fluctuations, aspects not fully conveyed by average BP values alone.</p><p><strong>Conclusion: </strong>BPV and TTR represent complementary, clinically meaningful measures that improve CV risk stratification beyond mean BP. Their integration into routine hypertension management may enhance identification of residual risk, and support more individualized treatment strategies .</p>","PeriodicalId":9000,"journal":{"name":"Blood Pressure","volume":" ","pages":"2653312"},"PeriodicalIF":2.3,"publicationDate":"2026-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147589749","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Blood PressurePub Date : 2026-12-01Epub Date: 2026-01-12DOI: 10.1080/08037051.2026.2613530
Jinpeng Wen, Zilin Zhao, Hejia Wan
{"title":"Reconsidering the role of acupuncture in circadian blood pressure regulation: reflections and future directions.","authors":"Jinpeng Wen, Zilin Zhao, Hejia Wan","doi":"10.1080/08037051.2026.2613530","DOIUrl":"10.1080/08037051.2026.2613530","url":null,"abstract":"","PeriodicalId":9000,"journal":{"name":"Blood Pressure","volume":" ","pages":"2613530"},"PeriodicalIF":2.3,"publicationDate":"2026-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145931476","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Blood PressurePub Date : 2026-12-01Epub Date: 2026-05-07DOI: 10.1080/08037051.2026.2653314
Majdi M Alzoubi, Renad Mohammed, Marwa Al Barmawi, Hasan Abualruz, Khalid Al Mugheed, Mohammad Alzoubi, Maram Alzoubi, Nadiah A Baghdadi, Sally Mohammed Farghaly Abdelaliem
{"title":"Health literacy and its role in promoting medication adherence among hypertension patients.","authors":"Majdi M Alzoubi, Renad Mohammed, Marwa Al Barmawi, Hasan Abualruz, Khalid Al Mugheed, Mohammad Alzoubi, Maram Alzoubi, Nadiah A Baghdadi, Sally Mohammed Farghaly Abdelaliem","doi":"10.1080/08037051.2026.2653314","DOIUrl":"https://doi.org/10.1080/08037051.2026.2653314","url":null,"abstract":"<p><strong>Background: </strong>Health literacy (HL) is considered as one of the most important approaches for individual, societal, and systemic behaviour changes that promote drug adherence. This study conducted to examined the association between health literacy and medication adherence among hypertension patients.</p><p><strong>Methods: </strong>A cross-sectional design was utilised among 175 hypertensive patients from three public hospitals. The data collection was done for a duration of six weeks between February and March 2025, by using two tools High Blood Pressure Health Literacy Scale (HBP-HLS) and the Medication Adherence Report Scale (MARS-5), <i>via</i> self-reported methods. Descriptive statistics, Pearson's correlation coefficients, and multiple linear regression were performed.</p><p><strong>Results: </strong>The majority of the respondents were female (<i>n</i> = 100, 57.1%), with mean age was 58.4 years. The mean blood pressure readings of 142.3/87.1 mmHg. The mean total score was 22.56 (SD = 3.12) out of a possible 25, indicating a relatively high average level of self-reported adherence. In terms of total health literacy, participants had a mean total score of 30.76 out of 43 (SD = 6.42). A statistically significant with positive correlation between health literacy and medication adherence (<i>r</i> = 0.28, <i>p</i> < 0.01). Comorbidities, number of medications, educational level, income, and BMI were strong independent predictor for health literacy.</p><p><strong>Conclusion: </strong>Policymakers are advised to prioritise health literacy improving interventions through tailored education, simplified treatment regimens, and community-based support systems to promote sustainable, equitable hypertension care across diverse populations.</p>","PeriodicalId":9000,"journal":{"name":"Blood Pressure","volume":"35 1","pages":"2653314"},"PeriodicalIF":2.3,"publicationDate":"2026-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147833077","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Blood PressurePub Date : 2026-12-01Epub Date: 2025-12-27DOI: 10.1080/08037051.2025.2598105
Lilik Sukesi, Yunia Sribudiani, Steven Yulius Usman, Eric Ricardo Yonatan, Ahmedz Widiasta, Noormarina Indraswari, Ria Bandiara, Nanny Nm Soetedjo
{"title":"The role of epigenetics in hypertension of children and adolescents: a systematic review.","authors":"Lilik Sukesi, Yunia Sribudiani, Steven Yulius Usman, Eric Ricardo Yonatan, Ahmedz Widiasta, Noormarina Indraswari, Ria Bandiara, Nanny Nm Soetedjo","doi":"10.1080/08037051.2025.2598105","DOIUrl":"10.1080/08037051.2025.2598105","url":null,"abstract":"<p><strong>Aim: </strong>This systematic review study aimed to discuss about the possibility role of epigenetic in HTN of children and adolescent.</p><p><strong>Material and methods: </strong>This evidence-based research is implemented within the scope of the Preferred Reporting Item for Systematic Review and Meta-analysis (PRISMA) 2020. The data were analyzed qualitatively to assess the risk of bias, with the New Ottawa Scale (NOS) and Agency for Health Research and Quality (AHRQ) criteria as the thresholds. Our research highlights in particular showed that there is a role for epigenetics in HTN in children and adolescents.</p><p><strong>Conclusion: </strong>Fourteen journals were included to be qualitatively assessed. Eleven journals (78.5%) stated that there was a correlation between epigenetic and BP in children and adolescents, however each study examined different genes or loci. In summary, epigenetic modifications of various single nucleotide polymorphisms (SNPs) and other genes were associated with higher systolic and diastolic BP in children and adolescents.</p>","PeriodicalId":9000,"journal":{"name":"Blood Pressure","volume":" ","pages":"2598105"},"PeriodicalIF":2.3,"publicationDate":"2026-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145647301","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Blood PressurePub Date : 2026-12-01Epub Date: 2025-12-23DOI: 10.1080/08037051.2025.2607166
Li Qu, Yankai Ma, Xuan Zhao, Qianqian Zhu, Xueying Chen, Jing Jin, Guiping Xu
{"title":"Association of intraoperative mean arterial pressure with postoperative organ dysfunction in elderly hypertensive patients: a retrospective cohort study.","authors":"Li Qu, Yankai Ma, Xuan Zhao, Qianqian Zhu, Xueying Chen, Jing Jin, Guiping Xu","doi":"10.1080/08037051.2025.2607166","DOIUrl":"10.1080/08037051.2025.2607166","url":null,"abstract":"<p><strong>Background: </strong>Maintaining intraoperative mean arterial pressure (MAP) is crucial for surgical safety in elderly hypertensive patients, but the optimal target remains unclear. This study evaluated the association between different intraoperative MAP ranges and postoperative stress responses and organ function.</p><p><strong>Methods: </strong>We conducted a single-center retrospective cohort study of 368 elderly hypertensive patients undergoing surgery under general anaesthesia. Patients were categorised into three groups based on actual intraoperative MAP: 65-75 mmHg, 75-85 mmHg, and 85-95 mmHg. Postoperative stress markers (cortisol, C-reactive protein [CRP]) and organ function markers (cardiac, renal, neurologic) were analysed using routine perioperative data.</p><p><strong>Results: </strong>Patients in the low MAP group (65-75 mmHg) showed the highest postoperative cortisol and CRP levels, indicating stronger stress responses, and were more likely to experience myocardial and renal impairment. The high MAP group (85-95 mmHg) had a slightly increased cardiac load. The moderate MAP group (75-85 mmHg) demonstrated a balanced profile, with lower stress levels and better preservation of cardiac and renal function. Neurologic injury markers (NSE, S100β) and the incidence of postoperative delirium showed no statistically significant differences among groups, though trends towards higher values were observed in the low MAP group.</p><p><strong>Conclusion: </strong>Maintaining intraoperative MAP within 75-85 mmHg appears to reduce postoperative stress and preserve cardiac and renal function in elderly hypertensive patients. Neurologic outcomes did not differ significantly, but avoiding excessively low MAP may help minimise potential neurological risk.</p>","PeriodicalId":9000,"journal":{"name":"Blood Pressure","volume":" ","pages":"2607166"},"PeriodicalIF":2.3,"publicationDate":"2026-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145793142","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Blood PressurePub Date : 2026-12-01Epub Date: 2026-01-04DOI: 10.1080/08037051.2025.2607840
Sandra C Fuchs, Guilherme S Procianoy, Marcelo B Lucca, Leonardo K Valter, Arthur L Tavares, Beatriz P Camilo, Letícia R P Silveira, Juliano A Jorge, Fabio T Cichelero, Flavio D Fuchs
{"title":"Methodological insights and correlations of short-term BP variability indices.","authors":"Sandra C Fuchs, Guilherme S Procianoy, Marcelo B Lucca, Leonardo K Valter, Arthur L Tavares, Beatriz P Camilo, Letícia R P Silveira, Juliano A Jorge, Fabio T Cichelero, Flavio D Fuchs","doi":"10.1080/08037051.2025.2607840","DOIUrl":"10.1080/08037051.2025.2607840","url":null,"abstract":"<p><strong>Background: </strong>Blood Pressure Variability (BPV) is an independent risk factor for cardiovascular events. Short-term indices of BPV, such as standard deviation (SD), coefficient of variation (CV), average real variability (ARV), and Time Rate Index (TRI) are calculated using blood pressure (BP) measurements from 24-hour ambulatory blood pressure monitoring (ABPM). Although these indices have distinct units and amplitudes, their relationships have not been thoroughly investigated. This study aims to explore the correlation between the SD, CV, ARV, and TRI indices of short-term BPV.</p><p><strong>Methods: </strong>Data were collected during the baseline evaluation of hypertensive participants with obstructive sleep apnoea in a randomised controlled trial. Systolic BPV indices were measured using 24-hour systolic ABPM. Pearson correlation (<i>r</i>) and intraclass correlation (ICC) for consistency were calculated among the BPV indices.</p><p><strong>Results: </strong>Sixty-five participants aged ≥40 years were evaluated. SD, CV, and ARV showed high linear correlations, and their ICCs indicated moderate consistency between SD and CV, and between CV and ARV. In contrast, TRI exhibited weak correlations and no ICC consistency with the other indices.</p><p><strong>Conclusions: </strong>The strong linear correlations and moderate-to-high ICC consistency among SD, CV, and ARV suggest these indices may be used interchangeably in studies of short-term BPV and cardio-vascular outcomes. TRI, however, reflects a distinct construct and should be evaluated separately when assessing its prognostic value.</p>","PeriodicalId":9000,"journal":{"name":"Blood Pressure","volume":" ","pages":"2607840"},"PeriodicalIF":2.3,"publicationDate":"2026-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145793118","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Blood PressurePub Date : 2026-12-01Epub Date: 2026-03-27DOI: 10.1080/08037051.2026.2646368
Costantino Mancusi, Petra Sinigoj, Christina Antza, Andrej Belančić, Justina Motiejunaite, Heini Sánez Tähtisalo, Diana Ferrao, Paolo Palatini
{"title":"Measurement of blood pressure in European Society of Hypertension Excellence Centres: a survey by the Young Investigators Group of the European Society of Hypertension.","authors":"Costantino Mancusi, Petra Sinigoj, Christina Antza, Andrej Belančić, Justina Motiejunaite, Heini Sánez Tähtisalo, Diana Ferrao, Paolo Palatini","doi":"10.1080/08037051.2026.2646368","DOIUrl":"10.1080/08037051.2026.2646368","url":null,"abstract":"<p><strong>Background: </strong>Office blood pressure (BP) measurement is the cornerstone of hypertension diagnosis and risk stratification. Inaccurate BP readings can lead to significant misclassification, often overestimating BP and prompting unnecessary lifelong treatment. The Young Investigators Group of the European Society of Hypertension (YIG-ESH) conducted a structured, comprehensive survey among ESH Excellence Centres with the primary objective of providing an updated overview of BP measurement practices in routine clinical care.</p><p><strong>Methods: </strong>A 17-item survey was created to assess the different modalities, devices and techniques currently used for office BP measurement (OBPM) across ESH excellence centres. The survey was spread <i>via</i> email for 8 weeks (from December 2024 to February 2025).</p><p><strong>Results: </strong>The survey was sent out to 216 recipients and 96 responses have been collected (response rate 44%) from 29 different countries. Automated electronic devices were used routinely in almost all outpatient facilities (96.7%), while manual auscultatory devices were used in 33.3% of the healthcare facilities. Among manual auscultatory devices, aneroid devices were used by the majority of the participants (73.6%) and mercury sphygmomanometers by 28.8%. BP was measured in seated (91.7%), standing (43.8%) and supine position (32.3%). Most of the respondents performed three (68.8%) or two (22.9%) BP measurements per outpatient. Home BP monitoring was routinely advised by 98.9% of the respondents providing precise instructions on how to perform the required home BP measurements.</p><p><strong>Conclusion: </strong>Our survey reveals considerable discrepancies in BP measurement, even within highly specialised settings such as the ESH Excellence Centres, with substantial non-adherence to recommended guidelines.</p>","PeriodicalId":9000,"journal":{"name":"Blood Pressure","volume":" ","pages":"2646368"},"PeriodicalIF":2.3,"publicationDate":"2026-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147484503","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Blood PressurePub Date : 2026-12-01Epub Date: 2026-01-07DOI: 10.1080/08037051.2025.2605790
Andrej Belančić, Christina Antza, Petra Sinigoj, Janis Casper, Justina Motiejunaite, Diana Ferrao
{"title":"Empowering the next generation: the young Investigators Group of the European Society of Hypertension.","authors":"Andrej Belančić, Christina Antza, Petra Sinigoj, Janis Casper, Justina Motiejunaite, Diana Ferrao","doi":"10.1080/08037051.2025.2605790","DOIUrl":"10.1080/08037051.2025.2605790","url":null,"abstract":"","PeriodicalId":9000,"journal":{"name":"Blood Pressure","volume":" ","pages":"2605790"},"PeriodicalIF":2.3,"publicationDate":"2026-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145762124","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}