Blood Pressure最新文献

{"title":"White coat hypertension and left ventricle geometry in childhood.","authors":"Serap Ata, Duygu Övünç Hacıhamdioğlu, Deniz Cihan, Deniz Kılıç, Gülendam Koçak","doi":"10.1080/08037051.2025.2606499","DOIUrl":"10.1080/08037051.2025.2606499","url":null,"abstract":"<p><strong>Purpose: </strong>It is not clear whether white-coat hypertension (WCH) is related to the development of left ventricular geometry changes in children.</p><p><strong>Materials and methods: </strong>This retrospective, single-centre study categorised patients into obese and normal-weight groups. The obese cohort comprised 72 with hypertension (48 male, 12.3 ± 3.2 years), 40 with white-coat hypertension (WCH; 29 male, 12.9 ± 2.8 years) and 31 normotensive controls (18 male, 11.9 ± 2.2 years). The normal-weight cohort included 62 with hypertension (40 male, 12.9 ± 3.9 years), 32 with WCH (21 male, 12.5 ± 3.3 years) and 89 normotensive controls (60 male, 13.0 ± 2.1 years). Echocardiography and ambulatory blood pressure monitoring were performed for all participants with WCH or hypertension. Abnormal left ventricular geometry was defined as the presence of concentric remodelling, concentric left ventricular hypertrophy (LVH), or eccentric LVH.</p><p><strong>Results: </strong>The prevalence of abnormal left ventricular geometry demonstrated a significant, stepwise increase from the control group to the WCH and hypertension groups among normal-weight children (1%, 9.4% and 25.8%, respectively; <i>p</i> < .001). This graded trend was absent in children with obesity, where the prevalence was elevated across all groups but did not increase progressively with the severity of the blood pressure phenotype (19.3%, 15% and 45.8%, respectively; <i>p</i> = .002).</p><p><strong>Conclusion: </strong>These findings suggest that WCH may signify an intermediate cardiovascular risk state even in the absence of obesity. From a preventive medicine perspective, the identification of WCH in normal-weight children warrants periodic blood pressure monitoring. While our study clearly establishes the presence of this association in normal-weight youth, the specific nature of the interaction between WCH and obesity - whether additive or synergistic - warrants further investigation in larger, longitudinal cohorts.</p>","PeriodicalId":9000,"journal":{"name":"Blood Pressure","volume":" ","pages":"2606499"},"PeriodicalIF":2.3,"publicationDate":"2026-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145779969","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The effect of fludrocortisone and midodrine on ambulatory blood pressure biomarkers and symptoms of syncope.","authors":"Kate Doyle, Ciara P Rice, Rose Anne Kenny, Robert Briggs, Amanda H Lavan","doi":"10.1080/08037051.2026.2618319","DOIUrl":"10.1080/08037051.2026.2618319","url":null,"abstract":"<p><strong>Introduction: </strong>Fludrocortisone and midodrine are frequently used to raise blood pressure (BP) in patients with vasovagal syncope (VVS)/low BP phenotype and orthostatic hypotension (OH), despite limited supporting evidence. This study assesses changes in Ambulatory Blood Pressure Monitor (ABPM) biomarkers and symptoms of syncope after commencing/increasing fludrocortisone or midodrine.</p><p><strong>Methods: </strong>Patients attending a tertiary-referral falls & syncope unit and prescribed fludrocortisone/midodrine were included. ABPM at index visit and follow-up (after commencing/increasing fludrocortisone/midodrine) were analysed, with specific focus on biomarkers of syncope risk: overall systolic BP (sBP), minimum sBP, and 'dips' in sBP <100 mmHg. Symptoms of presyncope and syncope were assessed at follow-up. These variables were compared pre and post medication changes using paired t-tests.</p><p><strong>Results: </strong>110 patient reviews (median age 57.0 (95%CI 46.4-63.8) years, 77% female) were followed for median 4.0 (IQR 2.0-8.0) months. Of these, 52% (57/110) commenced/increased fludrocortisone, and 48% (53/110) commenced/increased midodrine. Fludrocortisone use was associated with significant increases in overall sBP, minimum sBP and reduction in sBP dips <100mmHg. Symptoms of presyncope improved in 73.7% participants commencing/increasing fludrocortisone. Only 9/27 outcomes reached statistical significance in participants commencing/increasing midodrine: overall sBP increase commencing midodrine, overall sBP increase increasing midodrine (including subgroup ≥65 years), overall sBP increase commencing/increasing midodrine (including subgroup ≥65 years), minimum sBP increase commencing midodrine (including subgroup <65 years), decrease in sBP dips <100mmHg in subgroup aged ≥65 years increasing midodrine, and decrease in sBP dips <100mmHg in subgroup ≥65 years commencing/increasing midodrine. Symptoms of presyncope improved in 64.2% participants commencing/increasing midodrine.</p><p><strong>Conclusion: </strong>This study provides clinical data on the effectiveness of fludrocortisone and midodrine in patients with VVS/low BP phenotype and OH. Both fludrocortisone and midodrine significantly improved markers of future syncope risk, with fludrocortisone use showing a relatively greater effect.</p>","PeriodicalId":9000,"journal":{"name":"Blood Pressure","volume":" ","pages":"2618319"},"PeriodicalIF":2.3,"publicationDate":"2026-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145988086","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"24-month single-pill, triple antihypertensive therapy in rural Rwanda.","authors":"Isabella Hunjan, Clara Stroppa, Alice Umulisa, Gianfranco Parati, Mario G Bianchetti, Bienvenu Muvunyi, Willy Mucyo, Evariste Ntaganda, Sebastiano A G Lava, Franco Muggli","doi":"10.1080/08037051.2026.2635838","DOIUrl":"10.1080/08037051.2026.2635838","url":null,"abstract":"<p><strong>Introduction: </strong>Arterial hypertension is a leading modifiable cardiovascular risk factor. Recent guidelines recommend single-pill, low-dose combinations as initial pharmacological strategy. We investigated the long-term feasibility and sustained effect of such a strategy in a remote rural area of Southern Rwanda, in sub-Saharan Africa.</p><p><strong>Methods: </strong>Hypertension was diagnosed using three sets of blood pressure measurements obtained according to European Society of Hypertension recommendations using a validated oscillometric device (OMRON M7 IT-HEM-7322-E). Individuals meeting diagnostic criteria were initiated on a single-pill combination of amlodipine, hydrochlorothiazide, and olmesartan. Treatment dosage was reassessed and adjusted as needed at each outpatient clinic visit.</p><p><strong>Results: </strong>Fifty-seven Black African participants with confirmed uncomplicated, untreated hypertension (aged 65 [54-70] years; median and interquartile range) had follow-up data available for up to 24 months after inclusion. Blood pressure <140/90 mm Hg was achieved in 37 (65%) participants after 1 month, 51 (89%) after 3 months, 44 (77%) after 6 months, 43 (75%) after 12 months, and 47 (83%) after 24 months.</p><p><strong>Conclusion: </strong>Long-term management of arterial hypertension with a once-daily single-pill combination of amlodipine, hydrochlorothiazide, and olmesartan as initial therapy is feasible in a rural sub-Saharan African setting. Blood pressure reduction is sustained for at least 24 months. Single-pill combinations should be made accessible even in remote areas of low- and middle-income countries.</p>","PeriodicalId":9000,"journal":{"name":"Blood Pressure","volume":" ","pages":"2635838"},"PeriodicalIF":2.3,"publicationDate":"2026-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147281935","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Europe's hotspot region for hypertension: the Balkans.","authors":"Haci Hasan Yeter, Mustafa Arıcı","doi":"10.1080/08037051.2026.2650019","DOIUrl":"10.1080/08037051.2026.2650019","url":null,"abstract":"<p><strong>Purpose: </strong>Hypertension remains the leading modifiable risk factor for cardiovascular morbidity and premature mortality worldwide. While its prevalence has declined across much of Europe in recent decades, this trend has not been observed in the Balkan region, where rates remain persistently high. This narrative review aims to synthesise current evidence on the epidemiology of hypertension in the Balkans and to explore potential determinants underlying this sustained burden.</p><p><strong>Materials and methods: </strong>We conducted a narrative review of available literature, including population-based surveys, reports from the World Health Organization, and national epidemiological data from Balkan countries. Relevant studies were identified to evaluate prevalence patterns and associated determinants of hypertension across the region.</p><p><strong>Results: </strong>Data consistently indicate that hypertension prevalence in most Balkan countries approaches or exceeds 50% of the adult population. However, notable intra-regional variation exists, with Türkiye and Greece demonstrating prevalence levels closer to global averages. The excess burden of hypertension in the Balkans appears to be multifactorial, associated with persistently high dietary salt intake, socioeconomic disparities, structural limitations in healthcare systems, and region-specific environmental influences. These factors act synergistically rather than independently.</p><p><strong>Conclusion: </strong>The Balkan region represents a distinct epidemiological hotspot for hypertension within Europe. The sustained high prevalence is likely driven by the convergence of multiple interacting determinants, in contrast to Western Europe where long-term investments in primary care-based prevention have led to declining rates. Effective management of hypertension in the Balkans will require integrated, context-specific strategies that extend beyond individual-level interventions.</p>","PeriodicalId":9000,"journal":{"name":"Blood Pressure","volume":" ","pages":"2650019"},"PeriodicalIF":2.3,"publicationDate":"2026-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147497417","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Mechanistic distinctions matter: interpreting genetic and epigenetic evidence in pediatric blood pressure research.","authors":"Nan Wang, Limin Zhang, Zilin Zhao","doi":"10.1080/08037051.2025.2601391","DOIUrl":"10.1080/08037051.2025.2601391","url":null,"abstract":"","PeriodicalId":9000,"journal":{"name":"Blood Pressure","volume":" ","pages":"2601391"},"PeriodicalIF":2.3,"publicationDate":"2026-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145706687","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effects of whole-body vibration training on resting blood pressure in adults: a systematic review and meta-analysis of randomised controlled trials.","authors":"Yan Pan, Ping Luo, Binbin Jia, Junpeng Pang","doi":"10.1080/08037051.2026.2648316","DOIUrl":"10.1080/08037051.2026.2648316","url":null,"abstract":"<p><strong>Objective: </strong>To investigate the effect of whole‑body vibration training (WBVT) on resting blood pressure (BP) in adults and its moderating factors through a meta‑analysis.</p><p><strong>Methods: </strong>PubMed, Cochrane Library, Embase, and Web of Science were systematically searched up to 2 December 2025, with systolic BP (SBP) and diastolic BP (DBP) as the primary outcomes. Using Stata 17.0 software, effect sizes were pooled with a random‑effects model, and results were reported as weighted mean differences (WMDs) with 95% confidence intervals.</p><p><strong>Results: </strong>This meta-analysis included 14 randomised controlled trials (RCTs) involving 490 adult participants. WBVT significantly reduced SBP (WMD = -6.57 mmHg, 95% CI [-8.84, -4.29]; <i>p</i> < 0.01) and DBP (WMD = -3.01 mmHg, 95% CI [-4.32, -1.71]; <i>p</i> < 0.01) in adults. Subgroup analyses showed greater BP reduction in individuals with higher baseline BP (SBP: -11.34 mmHg [95% CI: -13.45, -9.23]; <i>p</i> < 0.01; DBP: -6.15 mmHg [95% CI: -7.46, -4.83]; <i>p</i> < 0.01) and in those who were overweight or obese (SBP: -8.99 mmHg [95% CI: -11.18, -6.80]; <i>p</i> < 0.01; DBP: -3.98 mmHg [95% CI: -5.17, -2.78]; <i>p</i> < 0.01). Interventions using combined movement patterns also yielded more pronounced effects (SBP: -7.12 mmHg [95% CI: -9.73, -4.51]; <i>p</i> < 0.01; DBP: -3.30 mmHg [95% CI: -5.61, -0.79]; <i>p</i> < 0.01).</p><p><strong>Conclusion: </strong>WBVT significantly reduced resting BP in adults, particularly effective in those with higher baseline BP, overweight/obese, or using combined exercise protocols, but further high-quality RCTs are needed.</p>","PeriodicalId":9000,"journal":{"name":"Blood Pressure","volume":" ","pages":"2648316"},"PeriodicalIF":2.3,"publicationDate":"2026-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147618396","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Sociodemographic factors, comorbidities, and biochemical parameters associated with poor adherence to antihypertensive treatment among university employees from Southeast Mexico: a cross-sectional study.","authors":"César Augusto Cortez-Gómez, Manuel Alejandro Flores-Barrada, José Arnold González-Garrido, Rosa Giannina Castillo-Avila, Carlos Javier López-Victorio, Pedro Iván Arias-Vázquez, Juan Gabriel Tejas-Juárez, Eduardo De la Cruz-Cano, José Alfredo Díaz-Gandarilla","doi":"10.1080/08037051.2025.2600736","DOIUrl":"10.1080/08037051.2025.2600736","url":null,"abstract":"<p><strong>Purpose: </strong>Poor adherence to antihypertensive treatment is one of the leading causes of life-threatening complications in individuals with hypertension. Therefore, investigating the factors involved is essential. This study aimed to identify sociodemographic factors, comorbidities, and biochemical parameters associated with poor adherence to antihypertensive treatment among university employees in southeastern Mexico.</p><p><strong>Methods: </strong>A total of 259 hypertensive employees were included and grouped according to their level of adherence-high, moderate, or poor-using the MMAS-8 Scale. For group comparisons, the Kruskal-Wallis and χ² tests were used for continuous and categorical variables, respectively. To quantify the strength of these associations, a univariate binary logistic regression was performed, considering those variables that were significant in the preliminary comparative analyses. Additionally, to reinforce these observations, receiver operating characteristic (ROC) curves were constructed to evaluate the discriminative ability of biochemical parameters significantly associated with treatment adherence.</p><p><strong>Results: </strong>A higher prevalence of hypertensive employees with low educational and occupational status was observed in the poor-adherence group, with obesity and dyslipidaemia being the most frequent comorbidities among them. Elevated blood glucose, uric acid, and lipid levels were also significantly associated with poor adherence (<i>p</i> < 0.001).</p><p><strong>Conclusions: </strong>Educational institutions and healthcare systems should pay special attention to this working population, including, among other measures, medical follow-up, periodic monitoring of biochemical parameters, and the implementation of lifestyle changes.</p>","PeriodicalId":9000,"journal":{"name":"Blood Pressure","volume":" ","pages":"2600736"},"PeriodicalIF":2.3,"publicationDate":"2026-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145686999","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The effect of acupuncture on 24-hour ambulatory blood pressure and circadian rhythm in patients with essential hypertension: a systematic review and meta-analysis of randomised controlled trials.","authors":"Huawei Gao, Zhihong Li, Wenxiang Zhan, Fangfang Shen, Yan Lu, Wei Chen","doi":"10.1080/08037051.2025.2605798","DOIUrl":"10.1080/08037051.2025.2605798","url":null,"abstract":"<p><strong>Objective: </strong>This study aimed to evaluate the effect of acupuncture on 24-hour ambulatory blood pressure (BP) and its circadian rhythm in patients with essential hypertension (EH).</p><p><strong>Methods: </strong>A systematic search was conducted across five English databases (PubMed, the Cochrane Library, Embase, Web of Science, and The National Library of Medicine) and four Chinese databases (China National Knowledge Infrastructure, Wanfang Database, Chinese Biomedical Literature Database, and VIP Chinese Science and Technology Journal Full-Text Database). The search period for each database was from inception to 31 May 2025. A meta-analysis was performed using RevMan 5.4.1 software.</p><p><strong>Results: </strong>A total of 13 randomised controlled trials, involving 1,080 patients with EH, were included. The meta-analysis results showed that compared with the control group, the experimental (acupuncture) group demonstrated significantly lower values in the following parameters: 24-hour average systolic BP (SBP) (MD = -3.57, 95% confidence interval [CI]: -5.04 to -2.10, <i>p</i> < 0.001), 24-hour average diastolic BP (DBP) (MD = -3.61, 95% CI: -5.12 to -2.10, <i>p</i> < 0.001), 24-hour SBP variability (MD = -1.15, 95% CI: -1.57 to -0.73, <i>p</i> < 0.001), 24-hour DBP variability (MD = -0.96, 95% CI: -1.27 to -0.65, <i>p</i> < 0.001), 24-hour SBP load (MD = -3.47, 95% CI: -5.76 to -1.17, <i>p</i> = 0.003) and 24-hour DBP load (MD = -2.20, 95% CI: -4.08 to -0.31, <i>p</i> = 0.02).</p><p><strong>Conclusion: </strong>Compared with Western medication alone, acupuncture combined with Western medication shows significant advantages in improving ambulatory BP parameters, including 24-hour average BP, 24-hour BP variability, 24-hour BP load, and the BP circadian rhythm.</p>","PeriodicalId":9000,"journal":{"name":"Blood Pressure","volume":" ","pages":"2605798"},"PeriodicalIF":2.3,"publicationDate":"2026-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145762087","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Association between urine triclocarban concentration and the prevalence of hypertension based on a cross-sectional study.","authors":"Ming Yang, Guangwei Xia, Shenglan Zhou, Lin Du","doi":"10.1080/08037051.2026.2629115","DOIUrl":"10.1080/08037051.2026.2629115","url":null,"abstract":"<p><strong>Background: </strong>There is a correlation between triclocarban exposure and adverse health effects, but the association between triclocarban and hypertension remains unknown. This study is to investigate the relationship between urinary triclocarban and the risk of hypertension in adults.</p><p><strong>Methods: </strong>Participants were enrolled from the National Health and Nutrition Examination Surveys. The urinary concentrations of triclocarban were measured by derivatization gas chromatography-mass spectrometry. Odds ratio (OR) and 95% confidence interval (CI) of urinary triclocarban associating with hypertension were estimated with by multivariable logistic regressions. Non-linear correlations were explored using restricted cubic splines. Subgroup analysis was carried out to examine the interactive effects.</p><p><strong>Results: </strong>The highest tertiles of triclocarban comparing the lowest tertiles was associated with higher risk of hypertension in unadjusted model (OR 1.93, 95%CI 1.53 to 2.44; <i>p</i> < 0.001), partly-adjusted model (OR 1.48, 95%CI 1.11 to 1.97; <i>p</i> = 0.008), and fully-adjusted model (OR 1.31, 95%CI 1.02 to 1.80; <i>p</i> = 0.043). Subgroup analysis showed that the relationship was consistent across gender, age, race, and BMI groups.</p><p><strong>Conclusions: </strong>Urinary triclocarban was associated with the prevalence of hypertension, after adjusting for traditional risk factors.</p>","PeriodicalId":9000,"journal":{"name":"Blood Pressure","volume":" ","pages":"2629115"},"PeriodicalIF":2.3,"publicationDate":"2026-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146123554","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Patient engagement with home blood pressure monitoring - cannot have been properly assessed during the pandemic.","authors":"Julian Eek Mariampillai, Camilla Lund Søraas, Sverre E Kjeldsen","doi":"10.1080/08037051.2026.2631272","DOIUrl":"10.1080/08037051.2026.2631272","url":null,"abstract":"","PeriodicalId":9000,"journal":{"name":"Blood Pressure","volume":" ","pages":"2631272"},"PeriodicalIF":2.3,"publicationDate":"2026-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146155779","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}