Blood Pressure最新文献

{"title":"White coat hypertension and left ventricle geometry in childhood.","authors":"Serap Ata, Duygu Övünç Hacıhamdioğlu, Deniz Cihan, Deniz Kılıç, Gülendam Koçak","doi":"10.1080/08037051.2025.2606499","DOIUrl":"10.1080/08037051.2025.2606499","url":null,"abstract":"<p><strong>Purpose: </strong>It is not clear whether white-coat hypertension (WCH) is related to the development of left ventricular geometry changes in children.</p><p><strong>Materials and methods: </strong>This retrospective, single-centre study categorised patients into obese and normal-weight groups. The obese cohort comprised 72 with hypertension (48 male, 12.3 ± 3.2 years), 40 with white-coat hypertension (WCH; 29 male, 12.9 ± 2.8 years) and 31 normotensive controls (18 male, 11.9 ± 2.2 years). The normal-weight cohort included 62 with hypertension (40 male, 12.9 ± 3.9 years), 32 with WCH (21 male, 12.5 ± 3.3 years) and 89 normotensive controls (60 male, 13.0 ± 2.1 years). Echocardiography and ambulatory blood pressure monitoring were performed for all participants with WCH or hypertension. Abnormal left ventricular geometry was defined as the presence of concentric remodelling, concentric left ventricular hypertrophy (LVH), or eccentric LVH.</p><p><strong>Results: </strong>The prevalence of abnormal left ventricular geometry demonstrated a significant, stepwise increase from the control group to the WCH and hypertension groups among normal-weight children (1%, 9.4% and 25.8%, respectively; <i>p</i> < .001). This graded trend was absent in children with obesity, where the prevalence was elevated across all groups but did not increase progressively with the severity of the blood pressure phenotype (19.3%, 15% and 45.8%, respectively; <i>p</i> = .002).</p><p><strong>Conclusion: </strong>These findings suggest that WCH may signify an intermediate cardiovascular risk state even in the absence of obesity. From a preventive medicine perspective, the identification of WCH in normal-weight children warrants periodic blood pressure monitoring. While our study clearly establishes the presence of this association in normal-weight youth, the specific nature of the interaction between WCH and obesity - whether additive or synergistic - warrants further investigation in larger, longitudinal cohorts.</p>","PeriodicalId":9000,"journal":{"name":"Blood Pressure","volume":" ","pages":"2606499"},"PeriodicalIF":2.3,"publicationDate":"2026-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145779969","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The effect of fludrocortisone and midodrine on ambulatory blood pressure biomarkers and symptoms of syncope.","authors":"Kate Doyle, Ciara P Rice, Rose Anne Kenny, Robert Briggs, Amanda H Lavan","doi":"10.1080/08037051.2026.2618319","DOIUrl":"10.1080/08037051.2026.2618319","url":null,"abstract":"<p><strong>Introduction: </strong>Fludrocortisone and midodrine are frequently used to raise blood pressure (BP) in patients with vasovagal syncope (VVS)/low BP phenotype and orthostatic hypotension (OH), despite limited supporting evidence. This study assesses changes in Ambulatory Blood Pressure Monitor (ABPM) biomarkers and symptoms of syncope after commencing/increasing fludrocortisone or midodrine.</p><p><strong>Methods: </strong>Patients attending a tertiary-referral falls & syncope unit and prescribed fludrocortisone/midodrine were included. ABPM at index visit and follow-up (after commencing/increasing fludrocortisone/midodrine) were analysed, with specific focus on biomarkers of syncope risk: overall systolic BP (sBP), minimum sBP, and 'dips' in sBP <100 mmHg. Symptoms of presyncope and syncope were assessed at follow-up. These variables were compared pre and post medication changes using paired t-tests.</p><p><strong>Results: </strong>110 patient reviews (median age 57.0 (95%CI 46.4-63.8) years, 77% female) were followed for median 4.0 (IQR 2.0-8.0) months. Of these, 52% (57/110) commenced/increased fludrocortisone, and 48% (53/110) commenced/increased midodrine. Fludrocortisone use was associated with significant increases in overall sBP, minimum sBP and reduction in sBP dips <100mmHg. Symptoms of presyncope improved in 73.7% participants commencing/increasing fludrocortisone. Only 9/27 outcomes reached statistical significance in participants commencing/increasing midodrine: overall sBP increase commencing midodrine, overall sBP increase increasing midodrine (including subgroup ≥65 years), overall sBP increase commencing/increasing midodrine (including subgroup ≥65 years), minimum sBP increase commencing midodrine (including subgroup <65 years), decrease in sBP dips <100mmHg in subgroup aged ≥65 years increasing midodrine, and decrease in sBP dips <100mmHg in subgroup ≥65 years commencing/increasing midodrine. Symptoms of presyncope improved in 64.2% participants commencing/increasing midodrine.</p><p><strong>Conclusion: </strong>This study provides clinical data on the effectiveness of fludrocortisone and midodrine in patients with VVS/low BP phenotype and OH. Both fludrocortisone and midodrine significantly improved markers of future syncope risk, with fludrocortisone use showing a relatively greater effect.</p>","PeriodicalId":9000,"journal":{"name":"Blood Pressure","volume":" ","pages":"2618319"},"PeriodicalIF":2.3,"publicationDate":"2026-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145988086","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"24-month single-pill, triple antihypertensive therapy in rural Rwanda.","authors":"Isabella Hunjan, Clara Stroppa, Alice Umulisa, Gianfranco Parati, Mario G Bianchetti, Bienvenu Muvunyi, Willy Mucyo, Evariste Ntaganda, Sebastiano A G Lava, Franco Muggli","doi":"10.1080/08037051.2026.2635838","DOIUrl":"10.1080/08037051.2026.2635838","url":null,"abstract":"<p><strong>Introduction: </strong>Arterial hypertension is a leading modifiable cardiovascular risk factor. Recent guidelines recommend single-pill, low-dose combinations as initial pharmacological strategy. We investigated the long-term feasibility and sustained effect of such a strategy in a remote rural area of Southern Rwanda, in sub-Saharan Africa.</p><p><strong>Methods: </strong>Hypertension was diagnosed using three sets of blood pressure measurements obtained according to European Society of Hypertension recommendations using a validated oscillometric device (OMRON M7 IT-HEM-7322-E). Individuals meeting diagnostic criteria were initiated on a single-pill combination of amlodipine, hydrochlorothiazide, and olmesartan. Treatment dosage was reassessed and adjusted as needed at each outpatient clinic visit.</p><p><strong>Results: </strong>Fifty-seven Black African participants with confirmed uncomplicated, untreated hypertension (aged 65 [54-70] years; median and interquartile range) had follow-up data available for up to 24 months after inclusion. Blood pressure <140/90 mm Hg was achieved in 37 (65%) participants after 1 month, 51 (89%) after 3 months, 44 (77%) after 6 months, 43 (75%) after 12 months, and 47 (83%) after 24 months.</p><p><strong>Conclusion: </strong>Long-term management of arterial hypertension with a once-daily single-pill combination of amlodipine, hydrochlorothiazide, and olmesartan as initial therapy is feasible in a rural sub-Saharan African setting. Blood pressure reduction is sustained for at least 24 months. Single-pill combinations should be made accessible even in remote areas of low- and middle-income countries.</p>","PeriodicalId":9000,"journal":{"name":"Blood Pressure","volume":" ","pages":"2635838"},"PeriodicalIF":2.3,"publicationDate":"2026-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147281935","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Health system competence and care continuity in patients with hypertension: electronic cohort in Uruguay.","authors":"Marina Guglielmino, Javier Roberti, Agustina Mazzoni, Carolina Prado, Laura Gutiérrez, Candela Stella, Emilse Vitar, Jacqueline Ponzo, Natalia Cristoforone, Hannah Leslie, Vilma Irazola, Ezequiel García-Elorrio","doi":"10.1080/08037051.2026.2702689","DOIUrl":"10.1080/08037051.2026.2702689","url":null,"abstract":"<p><strong>Background: </strong>Despite efforts to improve hypertension management, control rates remain low. Effective control depends on care competence and continuity. We describe health system competence, care continuity, user experience, and health and economic outcomes among individuals with hypertension in Uruguay.</p><p><strong>Methods: </strong>This longitudinal study of randomly selected 200 adults aged ≥35 years with baseline blood pressure >140/90 mmHg and mobile phone access from the CESCAS 2010 cohort.. . Over eight months, participants completed baseline, six telephone follow-up, and a final surveys documenting health status, health system competence, care continuity, patient activation, user experience, and health and economic outcomes.</p><p><strong>Results: </strong>Mean age was 64.9 (9.7) years; 77% reported 'Excellent/Very good' health. Overall, 79.5% knew they had hypertension and were on treatment; 42.0% of the total sample had controlled blood pressure at baseline. Only 11.5% received all guideline-recommended clinical interventions. Regardless of coverage, 60.8% usually attended a primary care facility. Although 93.5% had at least one visit in 8 months, only 48.8% of newly diagnosed participants completed the three recommended visits. In all, 57.1% received care from the same professional in the same facility. Blood pressure control was achieved by 34.4% of those with known hypertension and 19.5% of newly diagnosed participants. Only 49% reported timely appointments availability. Patient activation was 70.5%, and 68.9% reported autonomy in decision-making.</p><p><strong>Conclusion: </strong>The low proportion of individuals receiving continuous, competent care, particularly among those newly diagnosed, underscores the need for targeted interventions to improve care quality.</p>","PeriodicalId":9000,"journal":{"name":"Blood Pressure","volume":" ","pages":"2702689"},"PeriodicalIF":2.3,"publicationDate":"2026-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148677060","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Europe's hotspot region for hypertension: the Balkans.","authors":"Haci Hasan Yeter, Mustafa Arıcı","doi":"10.1080/08037051.2026.2650019","DOIUrl":"10.1080/08037051.2026.2650019","url":null,"abstract":"<p><strong>Purpose: </strong>Hypertension remains the leading modifiable risk factor for cardiovascular morbidity and premature mortality worldwide. While its prevalence has declined across much of Europe in recent decades, this trend has not been observed in the Balkan region, where rates remain persistently high. This narrative review aims to synthesise current evidence on the epidemiology of hypertension in the Balkans and to explore potential determinants underlying this sustained burden.</p><p><strong>Materials and methods: </strong>We conducted a narrative review of available literature, including population-based surveys, reports from the World Health Organization, and national epidemiological data from Balkan countries. Relevant studies were identified to evaluate prevalence patterns and associated determinants of hypertension across the region.</p><p><strong>Results: </strong>Data consistently indicate that hypertension prevalence in most Balkan countries approaches or exceeds 50% of the adult population. However, notable intra-regional variation exists, with Türkiye and Greece demonstrating prevalence levels closer to global averages. The excess burden of hypertension in the Balkans appears to be multifactorial, associated with persistently high dietary salt intake, socioeconomic disparities, structural limitations in healthcare systems, and region-specific environmental influences. These factors act synergistically rather than independently.</p><p><strong>Conclusion: </strong>The Balkan region represents a distinct epidemiological hotspot for hypertension within Europe. The sustained high prevalence is likely driven by the convergence of multiple interacting determinants, in contrast to Western Europe where long-term investments in primary care-based prevention have led to declining rates. Effective management of hypertension in the Balkans will require integrated, context-specific strategies that extend beyond individual-level interventions.</p>","PeriodicalId":9000,"journal":{"name":"Blood Pressure","volume":" ","pages":"2650019"},"PeriodicalIF":2.3,"publicationDate":"2026-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147497417","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Blood pressure and cardiovascular protection in chronic kidney disease: things are moving in nephrology!","authors":"Sverre E Kjeldsen, Lene V Halvorsen, Michel Burnier","doi":"10.1080/08037051.2026.2728279","DOIUrl":"10.1080/08037051.2026.2728279","url":null,"abstract":"","PeriodicalId":9000,"journal":{"name":"Blood Pressure","volume":" ","pages":"2728279"},"PeriodicalIF":2.3,"publicationDate":"2026-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148863270","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Mechanistic distinctions matter: interpreting genetic and epigenetic evidence in pediatric blood pressure research.","authors":"Nan Wang, Limin Zhang, Zilin Zhao","doi":"10.1080/08037051.2025.2601391","DOIUrl":"10.1080/08037051.2025.2601391","url":null,"abstract":"","PeriodicalId":9000,"journal":{"name":"Blood Pressure","volume":" ","pages":"2601391"},"PeriodicalIF":2.3,"publicationDate":"2026-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145706687","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Self-reported health status and blood pressure medication use among persons living with hypertension in Kenya.","authors":"Samuel Salu, Annabelle Mortty, Joshua Okyere, David Mensah Otoo","doi":"10.1080/08037051.2026.2712023","DOIUrl":"10.1080/08037051.2026.2712023","url":null,"abstract":"<p><strong>Background: </strong>While existing studies established an association between self-reported health status and healthcare service utilisation, its association with Blood Pressure (BP) medication use among persons living with hypertension remains under-explored. This study examines the association between self-reported health status and BP medication use among persons living with hypertension in Kenya.</p><p><strong>Methods: </strong>We analysed data from the 2022 Kenya Demographic and Health Survey (KDHS). The primary outcome was BP medication use, while the main independent variable was self-reported health status. Logistic regression models were fitted to assess the association between self-reported health status and BP medication use.</p><p><strong>Results: </strong>We found that only 32.0% of women and 36.4% of men in this study reported consistent BP medication use. Women who reported moderate or poor health were significantly more likely to use BP medication compared to those who perceived their health as good (aOR = 1.8, 95% CI: 1.4-2.4; aOR = 1.9, 95% CI: 1.2-3.0) respectively. However, no significant association between self-reported health status and BP medication use was found among men. Women aged 20-24 years (aOR = 0.4, 95% CI: 0.2-0.9) and men aged 25-34 years (aOR = 0.2, 95% CI: 0.06-0.9) were less likely to use BP medication. Furthermore, women (aOR = 2.0, 95% CI: 1.1-3.8) and men (aOR = 2.0, 95% CI: 1.0-3.8) with diabetes were more likely to use BP medication.</p><p><strong>Conclusion: </strong>These findings emphasise the need for gender specific health education and behaviour change interventions t to improve hypertension management.</p>","PeriodicalId":9000,"journal":{"name":"Blood Pressure","volume":" ","pages":"2712023"},"PeriodicalIF":2.3,"publicationDate":"2026-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148598959","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effects of whole-body vibration training on resting blood pressure in adults: a systematic review and meta-analysis of randomised controlled trials.","authors":"Yan Pan, Ping Luo, Binbin Jia, Junpeng Pang","doi":"10.1080/08037051.2026.2648316","DOIUrl":"10.1080/08037051.2026.2648316","url":null,"abstract":"<p><strong>Objective: </strong>To investigate the effect of whole‑body vibration training (WBVT) on resting blood pressure (BP) in adults and its moderating factors through a meta‑analysis.</p><p><strong>Methods: </strong>PubMed, Cochrane Library, Embase, and Web of Science were systematically searched up to 2 December 2025, with systolic BP (SBP) and diastolic BP (DBP) as the primary outcomes. Using Stata 17.0 software, effect sizes were pooled with a random‑effects model, and results were reported as weighted mean differences (WMDs) with 95% confidence intervals.</p><p><strong>Results: </strong>This meta-analysis included 14 randomised controlled trials (RCTs) involving 490 adult participants. WBVT significantly reduced SBP (WMD = -6.57 mmHg, 95% CI [-8.84, -4.29]; <i>p</i> < 0.01) and DBP (WMD = -3.01 mmHg, 95% CI [-4.32, -1.71]; <i>p</i> < 0.01) in adults. Subgroup analyses showed greater BP reduction in individuals with higher baseline BP (SBP: -11.34 mmHg [95% CI: -13.45, -9.23]; <i>p</i> < 0.01; DBP: -6.15 mmHg [95% CI: -7.46, -4.83]; <i>p</i> < 0.01) and in those who were overweight or obese (SBP: -8.99 mmHg [95% CI: -11.18, -6.80]; <i>p</i> < 0.01; DBP: -3.98 mmHg [95% CI: -5.17, -2.78]; <i>p</i> < 0.01). Interventions using combined movement patterns also yielded more pronounced effects (SBP: -7.12 mmHg [95% CI: -9.73, -4.51]; <i>p</i> < 0.01; DBP: -3.30 mmHg [95% CI: -5.61, -0.79]; <i>p</i> < 0.01).</p><p><strong>Conclusion: </strong>WBVT significantly reduced resting BP in adults, particularly effective in those with higher baseline BP, overweight/obese, or using combined exercise protocols, but further high-quality RCTs are needed.</p>","PeriodicalId":9000,"journal":{"name":"Blood Pressure","volume":" ","pages":"2648316"},"PeriodicalIF":2.3,"publicationDate":"2026-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147618396","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The blood pressure control triangle: targets, home blood pressure monitoring, and workload.","authors":"Nikolaos Evangelidis, Vasileios Gkolias, Emmanouil Smyrnakis, Areti Triantafyllou","doi":"10.1080/08037051.2026.2710498","DOIUrl":"10.1080/08037051.2026.2710498","url":null,"abstract":"","PeriodicalId":9000,"journal":{"name":"Blood Pressure","volume":" ","pages":"2710498"},"PeriodicalIF":2.3,"publicationDate":"2026-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148629431","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}