L. A. Oliveira, F. Moreira, M. Pereira, Rayssa Fernandes Souza Coelho, Allyson Coelho Ribeiro, A. Martins, José Hugo Andrade Santos Dantas, I. C. C. G. E. Almendra, Í. A. Brandão, J. L. Gomes, Kamilla Gomes Sales Souza, L. Leal, Luís Gustavo Silva Bacelar Andrade, Vanessa Nepomuceno Fonseca Meneses, Luara Lis Barbosa Boson, A. Soares, Raimundo Pereira da Silva Neto
{"title":"First Brazilian Case of Peripheral Mononeuropathy Secondary to InfectionChikungunya Virus","authors":"L. A. Oliveira, F. Moreira, M. Pereira, Rayssa Fernandes Souza Coelho, Allyson Coelho Ribeiro, A. Martins, José Hugo Andrade Santos Dantas, I. C. C. G. E. Almendra, Í. A. Brandão, J. L. Gomes, Kamilla Gomes Sales Souza, L. Leal, Luís Gustavo Silva Bacelar Andrade, Vanessa Nepomuceno Fonseca Meneses, Luara Lis Barbosa Boson, A. Soares, Raimundo Pereira da Silva Neto","doi":"10.4172/2314-7326.1000256","DOIUrl":"https://doi.org/10.4172/2314-7326.1000256","url":null,"abstract":"Background: Chikungunya is an infection caused by an RNA-virus and transmitted from primates to humans by Aedes aegypti and Aedes albopictus mosquitoes. Usually, it causes fever, widespread exanthema, myalgia and severe diffuse joints pain but may present several complications, such as neurological manifestations. \u0000Case presentation: We describe a case of a 38-year-old man with diagnostic confirmation of chikungunya virus infection based on the clinical manifestations of the disease and positivity of the serological tests. He has evolved with peripheral mononeuropathy confirmed by clinical examination and electroneuromyography. \u0000Conclusion: Peripheral neuropathy may be a neurological complication of CHIKV infection and to the best of our knowledge this is the first Brazilian case of peripheral mononeuropathy secondary to CHIKV infection.","PeriodicalId":89982,"journal":{"name":"Journal of neuroinfectious diseases","volume":"152 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2017-07-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"75025568","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Congenital Cytomegalovirus Infection Diagnosis Case 24 Years Later While Following With The Cerebral Palsy Diagnosis","authors":"Y. G. Aras","doi":"10.4172/2314-7326.1000257","DOIUrl":"https://doi.org/10.4172/2314-7326.1000257","url":null,"abstract":"Cytomegalovirus (CMV) is the most common cause of intrauterine infection, occurring in upto 2% of all live births. Most women are asymptomatic or experience nonspecific symptoms, which can lead to long-term sequelae in newborns including neurological impairment, hearing loss, and mental retardation. In this study, the reveal of congenital CMV diagnosed after the calcification in the brain upon the increasing number of attacks in brain during the treatment with the diagnosis of cerebral palsy, mental retardation and epilepsy is presented.","PeriodicalId":89982,"journal":{"name":"Journal of neuroinfectious diseases","volume":"71 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2017-07-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"83190913","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
M. Nakanishi, N. Uchida, U. Kawai, M. Oono, M. Fujita-Nakata, M. Sanada, S. Nagayama, M. Matsui
{"title":"A Case of Mumps Virus Reinfection Manifesting as Severe Meningitis thatMimicked Tuberculous Meningitis","authors":"M. Nakanishi, N. Uchida, U. Kawai, M. Oono, M. Fujita-Nakata, M. Sanada, S. Nagayama, M. Matsui","doi":"10.4172/2314-7326.1000255","DOIUrl":"https://doi.org/10.4172/2314-7326.1000255","url":null,"abstract":"It is known that mumps is an acute and highly contagious systemic viral infection that occurs in childhood, the hallmark of which is parotid gland swelling. Although mumps infection in the central nervous system (CNS) is uncommon among adults in association with vaccinations generally administered in developed countries, CNS involvement can occur without parotitis. Here, we report such a case of severe meningitis due to reinfection by the mumps virus. Based on our findings, we propose that mumps meningitis can mimic tuberculous meningitis in regard to clinical symptoms and course, as well as laboratory test results of cerebrospinal fluid. Follow-up investigations that include key cytokines such as IL-6, IFN-γ, and TNF-β in the CSF are important for differential diagnosis.","PeriodicalId":89982,"journal":{"name":"Journal of neuroinfectious diseases","volume":"13 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2017-07-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"81753419","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Neurosyphilis Presenting with a Stroke-Like Syndrome","authors":"Anda Eilam, D. Grin, Sarit Avishay, R. Gilad","doi":"10.4172/2314-7326.1000254","DOIUrl":"https://doi.org/10.4172/2314-7326.1000254","url":null,"abstract":"Objectives: Syphilis is still a public health problem in the world. Israel is a country with high immigration rates, some of the new immigrants coming from countries with a high prevalence of syphilis. \u0000Patients: We want to report a series of 7 patients admitted to the neurology ward at the Kaplan Medical Center in Rechovot, Israel with acute strokes which ultimately were attributed to meningo-vascular syphilis. \u0000Methods: Retrospective observational study. \u0000Results: Six patients are presented with acute ischemic stroke and 1 with intra parenchymal hematoma. There were 6 male patients and one female. The mean age of the patients was younger than that of stroke patients in Israel. There were 6 patients of Ethiopian origin and one born in Israel. All the patients had positive VDRL and TPHA serology in the blood and all the patients that had LP performed had positive syphilis ELISA in the liver. Conclusion: Neurosyphilis should be considered among patients with stroke and the presence of more “traditional” cardiovascular risk factors should not prevent us from considering it.","PeriodicalId":89982,"journal":{"name":"Journal of neuroinfectious diseases","volume":"39 11 Pt 1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2017-06-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"82831318","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Central Nervous System Vasculopathy In Varicella Zoster Virus Infection","authors":"T. Mehta, N. Desai, Dimitre Mirtchev","doi":"10.4172/2314-7326.1000253","DOIUrl":"https://doi.org/10.4172/2314-7326.1000253","url":null,"abstract":"Varicella zoster virus is an exclusively human double-stranded DNA virus that is the causative factor for two \u0000 ubiquitous conditions: varicella in children and zoster in adults. Both conditions are associated with neurological complications. Centripetal trans-axonal spread via cranial nerve ganglia appears to afford entry into the central \u0000 nervous system. There is increasing evidence of varicella zoster virus playing a role in the development of giant cell \u0000 arteritis. First associated with transient ischemic attacks and ischemic strokes, vasculopathy secondary to varicella \u0000 zoster virus infections has now been associated with aneurysms that may or may not lead to subarachnoid \u0000 hemorrhage, multifocal vasculitis, arterial dissection, dolicoectasia, cortical venous sinus thrombosis, ischemic \u0000 cranial neuropathies and spinal cord infarction. Prior knowledge of the myriad clinical manifestations helps in early \u0000diagnosis and treatment of the complications.","PeriodicalId":89982,"journal":{"name":"Journal of neuroinfectious diseases","volume":"91 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2017-06-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"80533838","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Cerebral Aneurysm in Lyme Neuroborreliosis with Regression After Medical Treatment","authors":"J. Tiu, R. Hanson, R. Staudinger","doi":"10.4172/2314-7326.1000252","DOIUrl":"https://doi.org/10.4172/2314-7326.1000252","url":null,"abstract":"Lyme disease in the United States is caused predominantly by the spirochete Borrelia burgdorferi and affects \u0000 multiple organ systems. Lyme Borreliosis infrequently involves the peripheral and central nervous system, and the \u0000 term Neuroborreliosis is used for the latter case. The most common manifestations of Neuroborreliosis include \u0000 cranial neuropathy and lymphocytic meningitis. It can also cause cerebral vasculitis leading to both wall thickening \u0000 and endothelial obliteration. Other manifestations include stroke, with over 50 documented cases, and rarely nonaneurysmal \u0000subarachnoid hemorrhage and intraparenchymal hemorrhage. \u0000 Intracranial aneurysm detected in the setting of Lyme Borreliosis infection has been previously documented in \u0000 four cases [3,4]. However, the existence of a causal relationship between Lyme infection and intracranial aneurysm \u0000 has been debated. We discuss these cases, and present our own case of a man with Lyme Neuroborreliosis with an \u0000intracranial aneurysm which regressed upon completion of treatment with ceftriaxone.","PeriodicalId":89982,"journal":{"name":"Journal of neuroinfectious diseases","volume":"65 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2017-06-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"87356592","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Multidisciplinary Teams in Central Nervous System Infection","authors":"Yan Li, M. Luo","doi":"10.4172/2314-7326.1000251","DOIUrl":"https://doi.org/10.4172/2314-7326.1000251","url":null,"abstract":"Central nervous system (CNS) infection is one of the most common diseases of the nervous systemwhich is also one of the most fatal diseases worldwide. According to the World Health Organization, in 2004, 700,000 people were infected with meningitis and nearly half of them died of this disease.","PeriodicalId":89982,"journal":{"name":"Journal of neuroinfectious diseases","volume":"62 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2017-06-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"84498315","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Rabies Require Extra Caution in Endemic Areas","authors":"Prasanna Ks","doi":"10.4172/2314-7326.1000250","DOIUrl":"https://doi.org/10.4172/2314-7326.1000250","url":null,"abstract":"Rabies in man and animals has been discussed since centuries but still remains one of the neglected zoonotic diseases across the globe. Dogs being reservoir host, bite from an unknown dog and death of the bitten man or animal or of the dog that bit, within a span of ten days to three months, leave a suspicion of rabies especially in endemic areas like India. Though there are strict measures to control rabies by vaccination programmes, abundance of stray dogs makes it difficult to contain the disease. So, choosing the best diagnostic procedure is highly significant.","PeriodicalId":89982,"journal":{"name":"Journal of neuroinfectious diseases","volume":"118 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2017-06-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"78034407","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Tuberculous Meningitis, WhatâÂÂs New?","authors":"S. Lolachi, J. Janssens, D. Adler","doi":"10.4172/2314-7326.1000248","DOIUrl":"https://doi.org/10.4172/2314-7326.1000248","url":null,"abstract":"Tuberculous meningitis may not be the most common cause of bacterial meningitis in non-endemic countries, but it is certainly the most dangerous form of meningitis with a high morbidity and mortality. The diagnosis is difficult and a delay in treatment initiation can lead to poor outcomes, including severe neurological disability. In the setting of world globalization and frequent travel to endemic areas, it is important that physicians be acquainted with this disease. This review discusses the most recent advances related to diagnosis and treatment regimens, including the challenges associated with the treatment of individuals with concomitant human immunodeficiency virus infection as well as advances in vaccination against mycobacterium tuberculosis.","PeriodicalId":89982,"journal":{"name":"Journal of neuroinfectious diseases","volume":"43 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2017-05-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"79323963","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
S. Makhlouf, M. Messelmani, I. Bedoui, M. Mansour, J. Zaouali, R. Mrissa
{"title":"Mild Encephalitis/Encephalopathy with a Reversible Splenial Lesion Due to Respiratory Syncytial Virus: Case Report","authors":"S. Makhlouf, M. Messelmani, I. Bedoui, M. Mansour, J. Zaouali, R. Mrissa","doi":"10.4172/2314-7326.1000249","DOIUrl":"https://doi.org/10.4172/2314-7326.1000249","url":null,"abstract":"Mild encephalitis/encephalopathy with a reversible splenial lesion (MERS) is a rare clinico-radiological entity, which is characterized by transient abnormalities in the splenium of the corpus callosum (SCC) associated with mild central nervous system (CNS) symptoms. MERS is often described in children, unlike in adults, which is rare. Its etiologies are variable, dominated by infectious causes. Its reversibility and favorable prognosis make all the particularity of this syndrome.","PeriodicalId":89982,"journal":{"name":"Journal of neuroinfectious diseases","volume":"54 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2017-05-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"89824639","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}