BJU International最新文献_第4页

A structured training curriculum for robot-assisted radical nephroureterectomy: a Delphi consensus study. 机器人辅助根治性肾输尿管切除术的结构化培训课程：德尔菲共识研究。

IF 4.5 2区医学

BJU International Pub Date : 2025-09-17 DOI: 10.1111/bju.70000

Farshad Sheybaee Moghaddam,Alireza Ghoreifi,Rashid K Sayyid,Zhenjie Wu,Firas Abdollah,Alessandro Antonelli,Daniel D Eun,Shengjie Guo,Andrew J Hung,Lulin Ma,Vitaly Margulis,Surena F Matin,Reza Mehrazin,James Porter,Aaron Potretzke,Benjamin Pradere,Morgan Roupret,Thomas Seisen,Shahrokh F Shariat,Giuseppe Simone,Robert J Stein,Long Wang,Jitao Wu,Evanguelos Xylinas,Lin Yao,Homayoun Zargar,Riccardo Autorino,Giovanni E Cacciamani,Hooman Djaladat

{"title":"A structured training curriculum for robot-assisted radical nephroureterectomy: a Delphi consensus study.","authors":"Farshad Sheybaee Moghaddam,Alireza Ghoreifi,Rashid K Sayyid,Zhenjie Wu,Firas Abdollah,Alessandro Antonelli,Daniel D Eun,Shengjie Guo,Andrew J Hung,Lulin Ma,Vitaly Margulis,Surena F Matin,Reza Mehrazin,James Porter,Aaron Potretzke,Benjamin Pradere,Morgan Roupret,Thomas Seisen,Shahrokh F Shariat,Giuseppe Simone,Robert J Stein,Long Wang,Jitao Wu,Evanguelos Xylinas,Lin Yao,Homayoun Zargar,Riccardo Autorino,Giovanni E Cacciamani,Hooman Djaladat","doi":"10.1111/bju.70000","DOIUrl":"https://doi.org/10.1111/bju.70000","url":null,"abstract":"OBJECTIVESTo develop an internationally validated, structured robot-assisted radical nephroureterectomy (RARNU) training programme through expert consensus.MATERIALS AND METHODSA RARNU-specific questionnaire was developed/adapted from previously published, validated questionnaires for robot-assisted urological procedures. This included five key domains and 11 surgical steps. In all, 30 upper tract urothelial carcinoma experts were invited to participate. A two-stage modified Delphi approach was employed. Consensus was defined as ≥80% agreement. Modifications and additional statements were proposed during the second round following qualitative/quantitative feedback from the initial round.RESULTSResponse rates for the first and second Delphi rounds were 80% (24/30) and 92% (22/24), respectively. All agreed that adoption of a standardised training curriculum can improve clinical outcomes during the RARNU learning curve. There was ≥92% agreement on all proposed RARNU steps. Five RARNU clinical modules of increasing complexity were defined using individual step difficulty and number of prior RARNU cases required, with ≥96% agreement among respondents. Respondents unanimously agreed that the final assessment should be based on a procedure-specific scale focusing on the hilar dissection, ureteric dissection, and bladder cuff excision steps. No consensus was reached for the annual minimum RARNU volume required for eligibility as a RARNU curriculum host centre.CONCLUSIONThis is the first structured training curriculum for RARNU using international expert consensus. This will help guide surgical educators and trainees toward independent completion of a full RARNU.","PeriodicalId":8985,"journal":{"name":"BJU International","volume":"17 1","pages":""},"PeriodicalIF":4.5,"publicationDate":"2025-09-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145071864","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Peri-operative outcomes of open, laparoscopic and robotic simple prostatectomy. 开放、腹腔镜和机器人单纯性前列腺切除术的围手术期疗效。

IF 4.5 2区医学

BJU International Pub Date : 2025-09-16 DOI: 10.1111/bju.16928

Nikolaos Pyrgidis,Philipp Weinhold,Gerald Bastian Schulz,Michael Atzler,Leo Federico Stadelmeier,Iason Papadopoulos,Christian Stief,Julian Marcon,Patrick Keller

{"title":"Peri-operative outcomes of open, laparoscopic and robotic simple prostatectomy.","authors":"Nikolaos Pyrgidis,Philipp Weinhold,Gerald Bastian Schulz,Michael Atzler,Leo Federico Stadelmeier,Iason Papadopoulos,Christian Stief,Julian Marcon,Patrick Keller","doi":"10.1111/bju.16928","DOIUrl":"https://doi.org/10.1111/bju.16928","url":null,"abstract":"OBJECTIVETo compare peri-operative outcomes and trends in open (OSP), laparoscopic (LSP) and robot-assisted simple prostatectomy (RASP).MATERIALS AND METHODSWe used German Nationwide Inpatient Data (GRAND), provided by the Research Data Centre of the Federal Bureau of Statistics, and performed multiple patient-level analyses.RESULTSBetween 2013 and 2023, 46 234 simple prostatectomies were performed in Germany for benign prostatic hyperplasia without concomitant bladder stones. Of these, 44 194 (96%) were performed with an open, 724 (1%) with a laparoscopic, and 1335 (3%) with a robotic approach. Among patients undergoing OSP, 11 755 (27%) cases were performed with a transcapsular and 32 439 (73%) with a transvesical approach. We compared transcapsular OSP vs RASP and LSP. The adoption of RASP increased exponentially during the period studied, while the use of OSP gradually declined, and that of LSP remained stable. In multivariable regression analyses, in-hospital transfusions were lower for LSP (6.5%; odds ratio [OR] 0.46, 95% confidence interval [CI] 0.34-0.62, P < 0.001) and RASP (7.3%; OR 0.58, 95% CI 0.47-0.72, P < 0.001) compared to OSP (13%). In-hospital urinary retention was significantly less frequent after LSP (4.6%; OR 0.46, 95% CI 0.32-0.65, P < 0.001) and RASP (6.4%; OR 0.68, 95% CI 0.54-0.85, P < 0.001) compared to OSP (9.3%). The median (interquartile range) hospital stay was 9 (8-12) days for OSP, 7 (6-9) days for RASP (P < 0.001) and 4 (4-7) days for LSP (P < 0.001). Transcapsular OSP was associated with a lower risk of intensive care unit admission (P < 0.001) and shorter hospital stay (P < 0.001) compared to transvesical OSP.CONCLUSIONOur results showed that RASP is rapidly growing and offers better peri-operative outcomes compared to OSP.","PeriodicalId":8985,"journal":{"name":"BJU International","volume":"65 1","pages":""},"PeriodicalIF":4.5,"publicationDate":"2025-09-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145068434","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Reply to Satapathy et al. 回复Satapathy等人。

IF 4.4 2区医学

BJU International Pub Date : 2025-09-16 DOI: 10.1111/bju.16915

Fumihiko Urabe, Yuma Goto, Takahiro Kimura

引用次数: 0

Ureteroenteric strictures following retrosigmoid vs. conventional ileal conduit – The MOSAIC study (The DaBlaCa‐16 study) 乙状结肠后输尿管狭窄vs.传统回肠导管- MOSAIC研究（DaBlaCa‐16研究）

IF 4.5 2区医学

BJU International Pub Date : 2025-09-12 DOI: 10.1111/bju.16894

Simone Buchardt Brandt, Stefanie Korsgaard Körner, Rikke Vilsbøll Milling, Ninna Kjær Nielsen, Ulla Nordström Joensen, Lasse Bro, Thor Knak Jensen, Astrid Helene Livbjerg, Knud Fabrin, Marie‐Louise Vrang, Gitte Wrist Lam, Michael Vangedal, Pernille Skjold Kingo, Jørgen Bjerggaard Jensen

{"title":"Ureteroenteric strictures following retrosigmoid vs. conventional ileal conduit – The MOSAIC study (The DaBlaCa‐16 study)","authors":"Simone Buchardt Brandt, Stefanie Korsgaard Körner, Rikke Vilsbøll Milling, Ninna Kjær Nielsen, Ulla Nordström Joensen, Lasse Bro, Thor Knak Jensen, Astrid Helene Livbjerg, Knud Fabrin, Marie‐Louise Vrang, Gitte Wrist Lam, Michael Vangedal, Pernille Skjold Kingo, Jørgen Bjerggaard Jensen","doi":"10.1111/bju.16894","DOIUrl":"https://doi.org/10.1111/bju.16894","url":null,"abstract":"ObjectivesTo evaluate the rate of left‐sided ureteroenteric strictures (UES) following robot‐assisted radical cystectomy (RARC) with a retrosigmoid ileal conduit compared to a conventional ileal conduit in a randomised controlled trial (RCT).Patients and MethodsThis multicentre, RCT included 303 patients undergoing RARC between May 2020 and August 2022. Patients were randomised to receive either a retrosigmoid or a conventional ileal conduit. Analyses were performed an intention‐to‐treat basis.ResultsOf the 149 patients randomised for the retrosigmoid ileal conduit, a total of 137 (92%) patients received the allocated conduit. In the control group, 150 of 154 (97.4%) patients underwent RARC and one patient was lost to follow‐up. At a median follow‐up of 754 days, the rate of left‐sided UES was 4.1% (six of 148) in the intervention group and 6.7% (10 of 149) in the control group (P = 0.31). No significant differences were observed in postoperative creatinine clearance or metabolic complications, including vitamin B12 deficiency and metabolic acidosis.ConclusionThe rate of left‐sided UES was not significantly reduced with the retrosigmoid conduit compared to the conventional approach. However, the procedure was feasible without increased risk of metabolic complications and therefore may be a good alternative when extensive resection of the left ureter is needed.","PeriodicalId":8985,"journal":{"name":"BJU International","volume":"74 1","pages":""},"PeriodicalIF":4.5,"publicationDate":"2025-09-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145035244","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Urinary tract events after radical radiotherapy (RT) for prostate cancer according to pre-RT International Prostate Symptom Score. 根据pre-RT国际前列腺症状评分，前列腺癌根治性放疗（RT）后尿路事件。

IF 4.5 2区医学

BJU International Pub Date : 2025-09-12 DOI: 10.1111/bju.16927

Paolo Zaurito,Marcus Westerberg,Hans Garmo,Rolf Gedeborg,Eugenio Ventimiglia,A Wilberg Orrason,Camilla Thellenberg-Karlsson,Pär Stattin,David Robinson

{"title":"Urinary tract events after radical radiotherapy (RT) for prostate cancer according to pre-RT International Prostate Symptom Score.","authors":"Paolo Zaurito,Marcus Westerberg,Hans Garmo,Rolf Gedeborg,Eugenio Ventimiglia,A Wilberg Orrason,Camilla Thellenberg-Karlsson,Pär Stattin,David Robinson","doi":"10.1111/bju.16927","DOIUrl":"https://doi.org/10.1111/bju.16927","url":null,"abstract":"OBJECTIVETo describe the risk of urinary tract events after radical radiotherapy (RT) according to pre-RT (IPSS) overall and within subgroups of prostate volume, type of RT, and use of neoadjuvant androgen-deprivation therapy (ADT), as men who undergo RT for prostate cancer have a risk of urinary tract events.PATIENTS AND METHODSMen in the National Prostate Cancer Register of Sweden who underwent RT between 2018 and 2023 for whom IPSS was registered at diagnosis were included. The IPSS was stratified as: low, 0-7; moderate, 8-19; and severe, 20-35 points. Urinary tract events were defined as lower urinary tract symptoms, infections, and urological procedures after treatment and assessed based on International Classification of Diseases and Related Health Problems, 10th Revision codes and procedures in The Patient Register. Competing risk of cumulative incidence proportion of urinary tract events at 3 year after RT was computed according to the IPSS, prostate volume, type of RT, and use of neoadjuvant ADT.RESULTSOf the 4436 men included, 43% had mild, 44% moderate, and 13% severe pre-RT IPSS. Incidence of urinary tract events after RT was 19% at 3 years for men with mild IPSS, 28% for moderate IPSS, and 39% for severe IPSS. The association between IPSS and urinary tract events was observed within subgroups based on prostate volume, type of RT, and use of neoadjuvant ADT. A 5-unit increase in IPSS carried a 20% increased risk of having a urinary tract event within 3 years.CONCLUSIONA higher pre-RT IPSS is an indicator of increased risk of urinary tract events after RT - both overall and within subgroups of prostate volume, type of RT, and use of neoadjuvant ADT.","PeriodicalId":8985,"journal":{"name":"BJU International","volume":"1 1","pages":""},"PeriodicalIF":4.5,"publicationDate":"2025-09-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145035998","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Cisplatin-ineligible patients with muscle-invasive bladder cancer demonstrate poor long-term survival following immediate radical cystectomy. 不适合顺铂治疗的肌肉浸润性膀胱癌患者在立即根治性膀胱切除术后表现出较差的长期生存率。

IF 4.5 2区医学

BJU International Pub Date : 2025-09-11 DOI: 10.1111/bju.16895

Adnan Fazili,Seyed Behzad Jazayeri,Kyle M Rose,Christopher Guske,Lexiaochuan Wen,Adri Durant,Megan Prunty,Laura Bukavina,Mark D Tyson,G Daniel Grass,Hongzhi Xu,Philippe E Spiess,Scott M Gilbert,Wade J Sexton,Logan Zemp,Rodrigo Rodrigues Pessoa,Michael Poch,Seth P Lerner,Roger Li

{"title":"Cisplatin-ineligible patients with muscle-invasive bladder cancer demonstrate poor long-term survival following immediate radical cystectomy.","authors":"Adnan Fazili,Seyed Behzad Jazayeri,Kyle M Rose,Christopher Guske,Lexiaochuan Wen,Adri Durant,Megan Prunty,Laura Bukavina,Mark D Tyson,G Daniel Grass,Hongzhi Xu,Philippe E Spiess,Scott M Gilbert,Wade J Sexton,Logan Zemp,Rodrigo Rodrigues Pessoa,Michael Poch,Seth P Lerner,Roger Li","doi":"10.1111/bju.16895","DOIUrl":"https://doi.org/10.1111/bju.16895","url":null,"abstract":"OBJECTIVESTo compare survival and oncological outcomes of cisplatin-ineligible patients (Cis-I) and cisplatin-eligible (Cis-E) patients with muscle-invasive bladder cancer (MIBC) undergoing immediate radical cystectomy (IRC), as IRC is currently considered the standard-of-care for Cis-I patients with MIBC.PATIENTS AND METHODSData from patients with clinical (c)T2-4cN0-1M0 MIBC undergoing IRC, between 2006 and 2021, were retrospectively analysed from four tertiary care centres in the United States. Overall, recurrence-free and event-free survival were described using the Kaplan-Meier method and tested using the log-rank test. For context, we compared survival outcomes against those in Cis-E patients with MIBC undergoing IRC from the Southwest Oncology Group (SWOG)-8710 trial.RESULTSOverall, 379 Cis-I and 125 Cis-E patients with cT2-4cN0-1M0 MIBC who underwent IRC were included. Cis-I patients included 44.8% cT3/4 vs 60% cT3/4 in the Cis-E group. Overall, 83.3% of Cis-I and 79.2% of Cis-E patients died during follow-up. The median event-free survival and overall survival were 14.5 and 60.1 months vs 12.1 and 28.8 months in favour of the Cis-E group (P < 0.001). Limitations include retrospective comparison of contemporary multi-institutional data with that of a randomised control trial.CONCLUSIONSThe Cis-I patients with MIBC undergoing IRC fared poorly, with a median overall survival of 14.5 (95% confidence interval 11.1-17.9) months, mostly due to non-cancer-related deaths. These results provide a benchmark for clinical trials exploring novel agents or alternative chemotherapy regimens in Cis-I patients with MIBC.","PeriodicalId":8985,"journal":{"name":"BJU International","volume":"35 1","pages":""},"PeriodicalIF":4.5,"publicationDate":"2025-09-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145032158","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Comment on Bertini et al.: area deprivation and PSA screening disparities. 评论Bertini等人：区域剥夺和PSA筛查差异。

IF 4.5 2区医学

BJU International Pub Date : 2025-09-08 DOI: 10.1111/bju.16923

Xing Wang

引用次数: 0

Guidelines for meta-analyses and systematic reviews in urology. 泌尿外科荟萃分析和系统评价指南。

IF 4.4 2区医学

BJU International Pub Date : 2025-09-08 DOI: 10.1111/bju.16864

Andrew J Vickers, Melissa Assel, Rodney L Dunn, Graeme MacLennan, Betsy Jane Becker, Richard D Riley

引用次数: 0

October's reviewers of the month 10月份的评论人