BJU International最新文献

{"title":"The exponential relationship between raised intrarenal pressure and bacteraemia.","authors":"Anne Hong,Marcel Leroi,Matthew Alberto,Damien Bolton,Gregory Jack","doi":"10.1111/bju.16856","DOIUrl":"https://doi.org/10.1111/bju.16856","url":null,"abstract":"OBJECTIVETo quantify the amount of irrigation and bacteria that are absorbed into the venous system at various intrarenal pressures (IRPs) during ureterorenoscopy (URS).METHODSWe performed in vivo and ex vivo experiments to quantify fluid and bacteria reabsorption during raised IRP. The in vivo models used porcine kidneys of six adult living female pigs under general anaesthesia to simulate URS at serially increased IRPs. For the ex vivo models, porcine kidneys were procured on ice using renal transplant protocols. The renal artery was flushed and perfused with 0.9% normal saline and the renal vein left open to collect continuous venous flow. The ureter was cannulated with a retrograde catheter and the renal pelvis was distended at incrementally greater IRPs using irrigation containing either: (i) 8% acetic acid or (ii) Escherichia coli (E. coli) solution. Venous effluent was sampled every 3 min and tested for: (i) H+ ion concentration or (ii) E. coli colony-forming units per mL.RESULTSPyelovenous backflow of electrolyte solution and E. coli bacteria was exponentially proportional to IRP. E. coli bacteraemia was present in the venous blood at 30 mmHg IRP in one of six living animals. By 60 mmHg, two animals had bacteraemia, three animals by 75 mmHg, five animals by 90 mmHg IRP, and all six animals by 120 mmHg. The in vitro laboratory studies verified these results and quantified the degree of pyelovenous backflow at each of these pressures. In vitro, increasing IRP from 30 mmHg to 60 mmHg demonstrated a threefold increase in CFU/ml of E. coli. However, increasing IRP by the same magnitude from 60 mmHg to 90 mmHg demonstrated a 60-fold increase in CFU/ml of E. coli bacteraemia, and this continued exponentially up to 200 mmHg.CONCLUSIONPyelovenous backflow increases exponentially after 60 mmHg IRP. Bacteraemia can occur at IRPs between 30 and 120 mmHg in living animals; bacteraemia occurred at an average IRP of 77 mmHg in our study.","PeriodicalId":8985,"journal":{"name":"BJU International","volume":"14 1","pages":""},"PeriodicalIF":4.5,"publicationDate":"2025-07-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144693207","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Guideline of guidelines: PSMA PET in staging newly diagnosed intermediate-risk prostate cancer.","authors":"Jonathon Carll,Weiwei Shi,Marlon Perera,Nathan Lawrentschuk,Thilakavathi Chengodu,Dixon Woon","doi":"10.1111/bju.16872","DOIUrl":"https://doi.org/10.1111/bju.16872","url":null,"abstract":"OBJECTIVETo provide a comprehensive review and analysis of guidelines from various professional and medical organisations regarding the use of prostate-specific membrane antigen (PSMA) positron emission tomography (PET) as a staging scan for men with newly diagnosed intermediate-risk prostate cancer (PCa).MATERIALS AND METHODSEnglish-language guidelines and recommendations from the following associations and societies were reviewed and critically analysed: European Association of Urology (EAU), American Urological Association (AUA), National Comprehensive Cancer Network (NCCN), National Institute for Health and Care Excellence (NICE), Canadian Urological Association (CUA), American Society for Clinical Oncology (ASCO), Society for Nuclear Medicine and Medical Imaging (SNMMI).RESULTSThere is significant disagreement among guidelines regarding whether PSMA PET is a useful staging tool for men with a new diagnosis of intermediate-risk PCa. There is a stronger consensus that PSMA PET is useful in staging high-risk PCa.CONCLUSIONWhilst there is a growing body of evidence that supports the use of PSMA PET in newly diagnosed PCa, there is significant disagreement regarding its use for men with intermediate-risk disease. Recommendations are generally weak and based on expert opinions. This is an area of considerable ongoing research, and guidelines are likely to change as new evidence emerges.","PeriodicalId":8985,"journal":{"name":"BJU International","volume":"704 1","pages":""},"PeriodicalIF":4.5,"publicationDate":"2025-07-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144693208","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Developing an artificial intelligence model for phase recognition in robot‐assisted radical prostatectomy","authors":"Hideto Ueki, Munenori Uemura, Kiyoyuki Chinzei, Kosuke Takahashi, Naoto Wakita, Yasuyoshi Okamura, Kotaro Suzuki, Yukari Bando, Takuto Hara, Tomoaki Terakawa, Akihisa Yao, Jun Teishima, Koji Chiba, Hideaki Miyake","doi":"10.1111/bju.16862","DOIUrl":"https://doi.org/10.1111/bju.16862","url":null,"abstract":"ObjectivesTo develop and evaluate a convolutional neural network (CNN)‐based model for recognising surgical phases in robot‐assisted laparoscopic radical prostatectomy (RARP), with an emphasis on model interpretability and cross‐platform validation.MethodsA CNN using EfficientNet B7 was trained on video data from 75 RARP cases with the hinotori robotic system. Seven phases were annotated: bladder drop, prostate preparation, bladder neck dissection, seminal vesicle dissection, posterior dissection, apical dissection, and vesicourethral anastomosis. A total of 808 774 video frames were extracted at 1 frame/s for training and testing. Validation was performed on 25 RARP cases using the da Vinci robotic system to assess cross‐platform generalisability. Gradient‐weighted class activation mapping was used to enhance interpretability by identifying key regions of interest for phase classification.ResultsThe CNN achieved 0.90 accuracy on the hinotori test set but dropped to 0.64 on the da Vinci dataset, thus indicating cross‐platform limitations. Phase‐specific F1 scores ranged from 0.77 to 0.97, with lower performance in the phase of seminal vesicle dissection, and apical dissection. Gradient‐weighted class activation mapping visualisations revealed the model's focus on central pelvic structures rather than transient instruments, enhancing interpretability and insights into phase classification.ConclusionsThe model demonstrated high accuracy on a single robotic platform but requires further refinement for consistent cross‐platform performance. Interpretability techniques will foster clinical trust and integration into workflows, advancing robotic surgery applications.","PeriodicalId":8985,"journal":{"name":"BJU International","volume":"13 1","pages":""},"PeriodicalIF":4.5,"publicationDate":"2025-07-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144677542","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Clinical features of medication-related osteonecrosis of the jaw in prostate cancer management.","authors":"Yuma Goto,Fumihiko Urabe,Yue Ogihara,Mana Nakata,Juria Nakano,Kensuke Fujiwara,Masaki Hashimoto,Yuhei Koike,Yuya Iwamoto,Keiichiro Miyajima,Wataru Fukuokaya,Kosuke Iwatani,Yu Imai,Yuzo Inaba,Kagenori Ito,Takafumi Yanagisawa,Masaya Murakami,Kojiro Tashiro,Katsuhito Watanabe,Jun Miki,Takahiro Kimura, ","doi":"10.1111/bju.16860","DOIUrl":"https://doi.org/10.1111/bju.16860","url":null,"abstract":"OBJECTIVETo evaluate the cumulative incidence of medication-related osteonecrosis of the jaw (MRONJ) in patients with prostate cancer and bone metastases receiving long-term denosumab treatment, and also the occurrence of severe MRONJ and risk factors associated with the development of both MRONJ and severe MRONJ.PATIENTS AND METHODSThis retrospective study included 624 patients with prostate cancer and bone metastases treated with denosumab between January 2015 and December 2024. Patients without bone metastasis or with insufficient clinical data were excluded. The study assessed the cumulative incidence of MRONJ, as well as risk factors associated with MRONJ of any stage and severe MRONJ (Stage ≥2). Cox regression analysis was used to identify independent risk factors.RESULTSThe cumulative incidence of MRONJ at 1, 2, 3, and 6 years was 4.6%, 9.6%, 20.3%, and 51.9%, respectively. For severe MRONJ, the corresponding rates were 2.4%, 6.7%, 13.1%, and 27.9%, respectively. Multivariate analysis identified the following independent risk factors for MRONJ: extent of disease grade ≥3 (hazard ratio [HR] 2.00, P = 0.009), use of anticoagulants and/or antiplatelets (HR 2.08, P = 0.026), and a history of dental treatment within the past 6 months (HR 2.29, P = 0.003). Denosumab administration at intervals >1 month was associated with a reduced risk (HR 0.46, P = 0.041).CONCLUSIONThis study demonstrates that long-term denosumab treatment in patients with prostate cancer and bone metastases is associated with a substantial cumulative incidence of MRONJ. Key risk factors were identified, along with a modifiable factor that may reduce risk. These findings suggest that adjusting denosumab dosing schedules could help mitigate MRONJ risk, underscoring the need for personalised treatment plans and early preventive strategies.","PeriodicalId":8985,"journal":{"name":"BJU International","volume":"49 1","pages":""},"PeriodicalIF":4.5,"publicationDate":"2025-07-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144664236","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Response to Veldi et al.: 'The diagnostic value of MRI for persistent prostate cancer following irreversible electroporation focal therapy' - a critical appraisal.","authors":"Kai Zhang,Jeremy Teoh,Pilar Laguna,Jean de la Rosette","doi":"10.1111/bju.16840","DOIUrl":"https://doi.org/10.1111/bju.16840","url":null,"abstract":"","PeriodicalId":8985,"journal":{"name":"BJU International","volume":"94 1","pages":""},"PeriodicalIF":4.5,"publicationDate":"2025-07-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144639736","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Impact of three-dimensional prostate models during robot-assisted radical prostatectomy on surgical margins and functional outcomes","authors":"Nawal Khan,&nbsp;Davide Prezzi,&nbsp;Nicholas Raison,&nbsp;Andrew Shepherd,&nbsp;Michela Antonelli,&nbsp;Nick Byrne,&nbsp;Maia Heath,&nbsp;Christopher Bunton,&nbsp;Carlo Seneci,&nbsp;Eoin Hyde,&nbsp;Andres Diaz-Pinto,&nbsp;Findlay Macaskill,&nbsp;Benjamin Challacombe,&nbsp;Jonathan Noel,&nbsp;Christian Brown,&nbsp;Ata Jaffer,&nbsp;Paul Cathcart,&nbsp;Margherita Ciabattini,&nbsp;Armando Stabile,&nbsp;Alberto Briganti,&nbsp;Giorgio Gandaglia,&nbsp;Francesco Montorsi,&nbsp;Sebastien Ourselin,&nbsp;Prokar Dasgupta,&nbsp;Alejandro Granados","doi":"10.1111/bju.16850","DOIUrl":"10.1111/bju.16850","url":null,"abstract":"<div>\u0000 \u0000 <section>\u0000 \u0000 <h3> Background</h3>\u0000 \u0000 <p>Robot-assisted radical prostatectomy (RARP) is the standard surgical procedure for the treatment of prostate cancer. RARP requires a trade-off between performing a wider resection in order to reduce the risk of positive surgical margins (PSMs) and performing minimal resection of the nerve bundles that determine functional outcomes, such as incontinence and potency, which affect patients’ quality of life. In order to achieve favourable outcomes, a precise understanding of the three-dimensional (3D) anatomy of the prostate, nerve bundles and tumour lesion is needed.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Study Design</h3>\u0000 \u0000 <p>This is the protocol for a single-centre feasibility study including a prospective two-arm interventional group (a 3D virtual and a 3D printed prostate model), and a prospective control group.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Endpoints</h3>\u0000 \u0000 <p>The primary endpoint will be PSM status and the secondary endpoint will be functional outcomes, including incontinence and sexual function.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Patients and Methods</h3>\u0000 \u0000 <p>The study will consist of a total of 270 patients: 54 patients will be included in each of the interventional groups (3D virtual, 3D printed models), 54 in the retrospective control group and 108 in the prospective control group. Automated segmentation of prostate gland and lesions will be conducted on multiparametric magnetic resonance imaging (mpMRI) using ‘AutoProstate’ and ‘AutoLesion’ deep learning approaches, while manual annotation of the neurovascular bundles, urethra and external sphincter will be conducted on mpMRI by a radiologist. This will result in masks that will be post-processed to generate 3D printed/virtual models. Patients will be allocated to either interventional arm and the surgeon will be given either a 3D printed or a 3D virtual model at the start of the RARP procedure. At the 6-week follow-up, the surgeon will meet with the patient to present PSM status and capture functional outcomes from the patient via questionnaires. We will capture these measures as endpoints for analysis. These questionnaires will be re-administered at 3, 6 and 12 months postoperatively.</p>\u0000 </section>\u0000 </div>","PeriodicalId":8985,"journal":{"name":"BJU International","volume":"136 3","pages":"420-428"},"PeriodicalIF":4.4,"publicationDate":"2025-07-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://bjui-journals.onlinelibrary.wiley.com/doi/epdf/10.1111/bju.16850","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144622010","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"August's reviewers of the month","authors":"","doi":"10.1111/bju.16852","DOIUrl":"10.1111/bju.16852","url":null,"abstract":"<p>Like most journals, BJUI relies on the hard work and dedication of its peer reviewers and we are grateful to them all. Each month the Editorial Team nominates peer reviewers whose reviews have stood out for their quality and timeliness and those selected as the best are highlighted on this page in recognition of their exceptional work.</p><p>Dr Luca Lambertini is an Academic Doctor based at the Careggi University Hospital in Florence (IT) with a clinical and academic interest in Uro-Oncology and Robot Assisted Surgery. He completed his medical degree at Univerity of Bologna (2013–18), followed by the Residency Programme at the Careggi University Hospital in Florence (IT) with research focused on Robot Assisted Radical Cystectomy with Intra Corporeal Neobladder. He attended a Research Fellowship at the University of Illinois in Chicago focused on Single Port surgery and Training programs. He is currently a Clinical Research Training Fellow undertaking his PhD at Careggi Hospital (IT) and UIH (2024+) in the development of a modular training program for Single Port Extraperitoneal Radical Prostatectomy.</p><p>Professor Arkadiusz Miernik, MD, PhD, FEBU, MHBA, is a senior urologist and academic based at the University Medical Center Freiburg, Germany, where he serves as Director of the Division of Urotechnology. He earned his medical degree from the Medical University of Vienna and completed his PhD and urology training in Freiburg. His clinical and scientific focus lies in minimally invasive urological surgery, innovations in endourology, and surgical education.</p><p>In 2015, he received the Maximilian Nitze Prize, the highest scientific award in German urology. Professor Miernik remains committed to advancing both clinical innovation and academic excellence in urology.</p><p>Dr Hari Vigneswaran is a physician–scientist with clinical training in urology and a focus on early cancer detection and translational diagnostics. He earned his medical degree from the Warren Alpert Medical School of Brown University and completed surgical training in urology at the University of Illinois at Chicago. He currently practices urology at Gundersen Health System in Wisconsin and is a clinical fellow at Karolinska University Hospital in Stockholm. He is also in his final year as a PhD candidate at the Department of Medical Epidemiology and Biostatistics (MEB) at Karolinska Institutet, where his research focuses on biomarker-driven strategies for prostate cancer screening and risk stratification. He currently serves as Chief Medical Officer at A3P, where he leads clinical development for precision diagnostic programs, including the implementation of Stockholm3.</p>","PeriodicalId":8985,"journal":{"name":"BJU International","volume":"136 2","pages":"175-176"},"PeriodicalIF":4.4,"publicationDate":"2025-07-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1111/bju.16852","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144615407","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Longer-term effects of intraoperative cone-beam computed tomography in percutaneous nephrolithotomy: 18-month retrospective randomised controlled trial analysis.","authors":"Chris A Suijker,Riemer A Kingma,Rosanne van Ee,Emelie N Steffens,Emanuela Altobelli,Mieke T J Bus,Igle J de Jong,Stijn Roemeling","doi":"10.1111/bju.16859","DOIUrl":"https://doi.org/10.1111/bju.16859","url":null,"abstract":"OBJECTIVESTo assess the longer-term impact of intraoperative cone-beam computed tomography (CBCT) on stone-related morbidity after percutaneous nephrolithotomy (PCNL), since intraoperative CBCT allows for the detection and removal of residual fragments during the same procedure, improving stone clearance and thereby potentially diminishing stone-related morbidity.PATIENTS AND METHODSThis study was a retrospective analysis of a previously conducted single-centre randomised controlled trial at a tertiary complex endourology centre, in which patients were randomised intraoperatively to PCNL with intraoperative CBCT or conventional PCNL. We analysed 18-month follow-up data to assess differences in stone-related events (SREs), including re-interventions, emergency department visits, and hospital admissions. Stone-free rates and time to stone recurrence, as determined by follow-up CT scans, were also evaluated.RESULTSThe CBCT group (n = 80) had a significantly lower detection rate of new or residual fragments >4 mm (hazard ratio [HR] 0.61, 95% confidence interval [CI] 0.38-0.97), with 29 (36%) cases during 18 months of follow-up compared to 40 (50%) cases in the conventional PCNL group (n = 80). The restricted mean (standard deviation [SD]) time to fragment detection was 420 (44) days in the CBCT group vs 318 (53) days in the conventional PCNL group. In the CBCT group, 15 (19%) cases experienced 26 SREs, compared to 23 (29%) cases with 39 SREs in the conventional PCNL group. The restricted mean (SD) time to SRE was 499 (26) days for CBCT cases, compared to 447 (39) days for conventional PCNL cases. The rate of SREs did not decrease significantly when comparing CBCT-PCNL to conventional PCNL (HR 0.61, 95% CI 0.32-1.17).CONCLUSIONThis study found 10% fewer patients with SREs in the 18-month period after PCNL with intraoperative CBCT compared to conventional PCNL. This difference is likely due to the notable increase in stone-free rates following a single PCNL with intraoperative CBCT.","PeriodicalId":8985,"journal":{"name":"BJU International","volume":"52 1","pages":""},"PeriodicalIF":4.5,"publicationDate":"2025-07-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144621988","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Sentinel lymph node staging in urological cancer surgery: advances in imaging, intra‐operative detection and translational research","authors":"Erik J. van Gennep, Gijs H. KleinJan, Teele Kuusk, Rick W.A. Verdijk, Esther M.K. Wit, Bas W.G. van Rhijn, Axel Bex, Laura S. Mertens","doi":"10.1111/bju.16848","DOIUrl":"https://doi.org/10.1111/bju.16848","url":null,"abstract":"ObjectivesTo review the clinical utility, outcome and possible future applications of sentinel lymph node biopsy (SLNB) in penile cancer (PeC), bladder cancer (BCa), prostate cancer (PCa), testicular cancer (TCa) and renal cell carcinoma (RCC), focusing in particular on current SLNB standards and exploring advancements in imaging agents, intra‐operative detection, surgical navigation, and the potential application of SLNB in translational and clinical research.MethodsA literature search was conducted in PubMed and EMBASE for studies published between 2000 and 2024, providing a narrative review of SLNB in oncological urology.ResultsIn PeC, SLNB offers a lower adverse event rate compared to inguinal lymph node (LN) dissection, while maintaining high detection rates and acceptable sensitivity (92%–96%) for identifying inguinal LN metastases. Similarly, in PCa, SLNB achieves a sensitivity of 95%, potentially reinforcing its role in nodal staging and guiding personalised treatment strategies. For RCC, BCa and TCa, SLNB is currently under investigation in trials. In RCC, detection rates seem acceptable; however, in BCa and TCa, detection rates and false‐negative rates vary, limiting its clinical usefulness. Contemporary approaches utilise various radiotracers, (fluorescent) dyes, and hybrid tracers for SLNB. Ongoing research refines tumour‐targeted LN detection, including prostate‐specific membrane antigen targeting in PCa, potential c‐MET targeting in PeC, and <jats:sup>89</jats:sup>Zr‐girentuximab in RCC.ConclusionThe use of SLNB has transformed nodal staging in PeC, influencing treatment decisions and reducing morbidity in patients undergoing surgery. In other urological malignancies, it has not yet established itself as a standard tool for nodal staging. Its impact on survival, quality of life, and translational research remains to be determined.","PeriodicalId":8985,"journal":{"name":"BJU International","volume":"112 1","pages":""},"PeriodicalIF":4.5,"publicationDate":"2025-07-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144611236","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Response to Zhu et al.","authors":"Davide Perri, Giorgio Bozzini","doi":"10.1111/bju.16854","DOIUrl":"https://doi.org/10.1111/bju.16854","url":null,"abstract":"","PeriodicalId":8985,"journal":{"name":"BJU International","volume":"109 1","pages":""},"PeriodicalIF":4.5,"publicationDate":"2025-07-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144603278","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}