The Open bone journal最新文献_第2页

The Effect of Physical Activity on Bone Accrual, Osteoporosis and Fracture Prevention 体育锻炼对骨骼生长、骨质疏松和骨折预防的影响

The Open bone journal Pub Date : 2011-05-20 DOI: 10.2174/1876525401103010011

A. Nordström, Taru Tervo, M. Högström

{"title":"The Effect of Physical Activity on Bone Accrual, Osteoporosis and Fracture Prevention","authors":"A. Nordström, Taru Tervo, M. Högström","doi":"10.2174/1876525401103010011","DOIUrl":"https://doi.org/10.2174/1876525401103010011","url":null,"abstract":"Background: Physical activity has been recommended for the prevention and even treatment of osteoporosis because it potentially can increase bone mass and strength during childhood and adolescence and reduce the risk of falling in older populations. However, few reports have systematically investigated the effect of physical activity on bone in men and women of different ages. Purpose: The goal of this study was to review the literature relating to the effect of physical activity on bone mineral density in men and women of various ages. Method: This review systematically evaluates the evidence for the effect of physical activity on bone mineral density. Cochrane and Medline databases were searched for relevant articles, and the selected articles were evaluated. Results: The review found evidence to support the effectiveness of weight bearing physical activity on bone accrual during childhood and adolescence. The effect of weight bearing physical activity was site-specific. In contrast, the role of physical activity in adulthood is primarily geared toward maintaining bone mineral density. The evidence for a protective effect of physical activity on bone is not as solid as that for younger individuals. Conclusions: The effect of weight bearing physical activity is seen in sites that are exposed to loading. There also seems to be a continuous adaptive response in bone to loading. Additional randomized, controlled studies are needed to evaluate the effect of physical activity in the elderly.","PeriodicalId":89634,"journal":{"name":"The Open bone journal","volume":"29 1","pages":"11-21"},"PeriodicalIF":0.0,"publicationDate":"2011-05-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"68144990","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 16

Association between Self-Perceived Health, Physical Activity, and BMD in Aging Men and Women 老年男性和女性自我感知健康、身体活动和骨密度之间的关系

The Open bone journal Pub Date : 2011-03-29 DOI: 10.2174/1876525401103010006

Taru Tervo, P. Nordström, A. Nordström

引用次数: 3

Delayed Fracture Healing in Alcohol Abusers—A Preliminary Retrospective Study 酒精滥用者骨折延迟愈合的初步回顾性研究

The Open bone journal Pub Date : 2011-02-28 DOI: 10.2174/1876525401103010001

A. Askew, D. Chakkalakal, X. Fang, M. Mcguire

引用次数: 11

Skeletal Age as a Determinant of Phalangeal Quantitative Ultrasound Measures of Bone Quality in Children and Adolescents 骨骼年龄是儿童和青少年指骨定量超声测量骨质量的决定因素

The Open bone journal Pub Date : 2010-12-29 DOI: 10.2174/1876525401002010038

M. Vignolo, C. Torrisi, A. Parodi, F. Becchetti, F. Terlizzi, G. Aicardi

{"title":"Skeletal Age as a Determinant of Phalangeal Quantitative Ultrasound Measures of Bone Quality in Children and Adolescents","authors":"M. Vignolo, C. Torrisi, A. Parodi, F. Becchetti, F. Terlizzi, G. Aicardi","doi":"10.2174/1876525401002010038","DOIUrl":"https://doi.org/10.2174/1876525401002010038","url":null,"abstract":"Background: Quantitative ultrasonography of the proximal phalanges of the hand (QUS) has emerged as an attractive technical choice to assess bone quality features both in terms of bone mass and structure. Strong associations were found between QUS measures, chronological age and growth variables, such height, weight and pubertal stages. Aim: To evaluate the relationship between skeletal age and QUS variables and the influence of skeletal age on QUS variables after allowing for chronological age, height, weight and pubertal stage. Subjects and Methods: 235 healthy children and adolescents (85 boys and 150 girls) aged 3 - 18 years were examined. Height, weight, body mass index (BMI) were collected. Skeletal age was assessed by the third version of Tanner-Whitehouse method (TW3). QUS variables amplitude dependent speed of sound (AD-SoS, m/s) and bone transmission time (BTT, ∝sec) were measured by DBM Sonic BP IGEA sonograph. Results: Statistically significant positive correlations were found between AD-SoS and BTT and skeletal age (R2 = 0.76 in boys and 0.83 in girls for AD-SoS and 0.96 in boys and 0.93 in girls for BTT). A very close correlation was observed between skeletal age and BTT even after adjusting for chronological age, height, weight, and pubertal stage. In both sexes, chronological age, height and BTT resulted significant predictors of skeletal age. Conclusion: Skeletal age has emerged as an important determinant of phalangeal QUS measurements, mainly BTT. Skeletal maturity should be taken into account when QUS technology is used to evaluate bone mass and structure in children.","PeriodicalId":89634,"journal":{"name":"The Open bone journal","volume":"2 1","pages":"38-42"},"PeriodicalIF":0.0,"publicationDate":"2010-12-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"68144863","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

Opinion Statement of the Effect of Mechanical Stress on Cartilage Tissue Engineering~!2010-01-12~!2010-04-26~!2010-06-23~! 机械应力对软骨组织工程影响的意见声明2010-01-12 2010-04-26 2010-06-23

The Open bone journal Pub Date : 2010-06-23 DOI: 10.2174/1876525401002010032

K. Ando, T. Mimura, Y. Matsusue, K. Mori

{"title":"Opinion Statement of the Effect of Mechanical Stress on Cartilage Tissue Engineering~!2010-01-12~!2010-04-26~!2010-06-23~!","authors":"K. Ando, T. Mimura, Y. Matsusue, K. Mori","doi":"10.2174/1876525401002010032","DOIUrl":"https://doi.org/10.2174/1876525401002010032","url":null,"abstract":"Articular cartilage is characterized by its poor capacity for self-repair. Once articular cartilage is injured and defected, it cannot be spontaneously repaired and finally develops osteoarthritis (OA). OA is a major leading cause of severe activity limitations and disability, resulting in worldwide socio-economical burden. At present, there is no established therapy for adequate repair of damaged articular cartilage. Researchers have therefore attempted to establish the cartilage tissue engineering as an effective alternative treatment of cartilage repair. However, the articular cartilage repair still remains a clinical and scientific challenge. In cartilage tissue engineering, it is believed that cell source, scaffold and growth factors are three key factors for the desired result of cell therapy for the damaged cartilage repair. However, increasing evidence is showing that these key factors are not enough and other factors may be required to achieve the optimal outcome. Since normal articular cartilage is always subjected to mechanical stress in daily activities, mechanical stress has attracted much attention as fourth key factor in cartilage tissue engineering. However, the real impact of mechanical stress on cartilage tissue engineering is far from complete understanding. In this review, we summarize the accumulating knowledge of the effect of mechanical stress on cartilage tissue engineering and discuss about the challenges for the future.","PeriodicalId":89634,"journal":{"name":"The Open bone journal","volume":"2 1","pages":"32-37"},"PeriodicalIF":0.0,"publicationDate":"2010-06-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"68144792","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Fourier-Transform Raman Spectroscopy Study of the Ovariectomized Rat Model of Osteoporosis~!2009-09-30~!2010-02-11~!2010-03-25~! 去卵巢大鼠骨质疏松模型的傅里叶变换拉曼光谱研究2009-09-30 2010-02-11 2010-03-25

The Open bone journal Pub Date : 2010-04-07 DOI: 10.2174/1876525401002010024

R. A. Souza, Diego Pereira Jerônimo, H. A. Gouvêa, Murilo Xavier, M. T. Souza, H. Miranda, M. G. Tosato, A. Martin, Wellington Ribeiro

{"title":"Fourier-Transform Raman Spectroscopy Study of the Ovariectomized Rat Model of Osteoporosis~!2009-09-30~!2010-02-11~!2010-03-25~!","authors":"R. A. Souza, Diego Pereira Jerônimo, H. A. Gouvêa, Murilo Xavier, M. T. Souza, H. Miranda, M. G. Tosato, A. Martin, Wellington Ribeiro","doi":"10.2174/1876525401002010024","DOIUrl":"https://doi.org/10.2174/1876525401002010024","url":null,"abstract":"The ovariectomized rat model of osteoporosis was studied using FT-Raman spectroscopy on the surface of sitespecific bones. Twelve, 3 month old female Wistar rats (230 ± 10 g) were divided into two groups (n = 6 per group), one group was: ovariectomized (OVX) and the other sham-operated (SHAM). The rats were sacrificed to collect samples twelve weeks after the surgical operation. The right femur and tibia as well as the third lumbar vertebra were harvested and subjected to FT-Raman analysis on the following bones sites: femoral neck (FN), femoral mid-shaft (FS), proximal tibial metaphysis (PTM), tibial mid-shaft (TS), and lumbar vertebral body (LVB). Analysis of individual Raman peaks showed site-dependent variations in the bone: the ovariectomy induced lower mineral content (959 cm -1 ) in trabecular bone sites (FN, PTM and LVB) and higher matrix content (1265 and 1665 cm -1 ) in cortical bone sites (FS and TS). In addition, a lower mineral to matrix ratio and a higher carbonate/phosphate were observed in the OVX group, which indicated a change in bone chemical content and some degree of remodeling specially in the trabecular bone sites. These data support the hypothesis that FT-Raman spectroscopy can be used to evaluate the bone alterations induced by this experimental model.","PeriodicalId":89634,"journal":{"name":"The Open bone journal","volume":"2 1","pages":"24-31"},"PeriodicalIF":0.0,"publicationDate":"2010-04-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"68144778","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 7

Usefulness of FDG PET in Primary Bone Tumors~!2009-05-15~!2009-12-18~!2010-03-25~! FDG PET在原发性骨肿瘤中的应用2009-05-15 2009-12-18 2010-03-25

The Open bone journal Pub Date : 2010-03-25 DOI: 10.2174/1876525401002010019

T. Yanagawa, Hideomi Watanabe, T. Shinozaki, K. Takagishi

引用次数: 6

Dual X-Ray Absorptiometry of the Lumbar Spine but not the Hip: Any Problems with a Swiss Policy?~!2009-08-13~!2009-11-18~!2010-03-05~! 双x线腰椎而非髋关节的吸收测量:瑞士政策有什么问题吗?

The Open bone journal Pub Date : 2010-03-05 DOI: 10.2174/1876525401002010014

G. Goerres, J. Swanenburg, D. Uebelhart

{"title":"Dual X-Ray Absorptiometry of the Lumbar Spine but not the Hip: Any Problems with a Swiss Policy?~!2009-08-13~!2009-11-18~!2010-03-05~!","authors":"G. Goerres, J. Swanenburg, D. Uebelhart","doi":"10.2174/1876525401002010014","DOIUrl":"https://doi.org/10.2174/1876525401002010014","url":null,"abstract":"Introduction: Osteoporosis is a growing healthcare problem in societies with aging populations and DXA is increasingly important to evaluate patients at risk and measure effects of osteoporosis treatment. In Switzerland, as in most Western countries, growing expense of public healthcare forces public authorities to take cost-saving action. The restriction of reimbursement for DXA measurement of the hip might impact negatively on patient care. Methods: We retrospectively evaluated data of 770 patients (59.3 ± 14.6 years, 14 - 91 years; 91 male and 679 female) and analyzed the proportion of patients with low bone mass as based on DXA measurements of a hip/spine combination of measurements or a single measurement of the lumbar spine. Results: There was a significant number of discordant measurements of T-score values between lumbar spine and total hip compared to concordant measurement results in all patients (p<0.0001) and in postmenopausal women (p<0.0001). Conclusion: DXA measurement of the lumbar spine only may miss correct diagnosis of osteopenia or osteoporosis in a significant number of patients. Therefore, it is important to examine both lumbar spine and hip in order to maintain patient care standards.","PeriodicalId":89634,"journal":{"name":"The Open bone journal","volume":"2 1","pages":"14-18"},"PeriodicalIF":0.0,"publicationDate":"2010-03-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"68144728","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Medicinal Plants for the Management of Post Menopausal Osteoporosis: A Review~!2009-08-29~!2009-11-14~!2010-03-05~! 治疗绝经后骨质疏松症的药用植物研究进展2009-08-29 2009-11-14 2010-03-05

The Open bone journal Pub Date : 2010-03-05 DOI: 10.2174/1876525401002010001

A. Shirwaikar, Saleemulla Khan, Y. Kamariya, B. D. Patel, Falguni P Gajera

{"title":"Medicinal Plants for the Management of Post Menopausal Osteoporosis: A Review~!2009-08-29~!2009-11-14~!2010-03-05~!","authors":"A. Shirwaikar, Saleemulla Khan, Y. Kamariya, B. D. Patel, Falguni P Gajera","doi":"10.2174/1876525401002010001","DOIUrl":"https://doi.org/10.2174/1876525401002010001","url":null,"abstract":"Osteoporosis, a silent epidemic has become a major health hazard in recent years. Osteoporosis which increases bone fragility and thereby the risk of fractures is associated with high mortality, morbidity and high medical expenses throughout the world. Though ovarian hormone deficiency is a major risk factor for osteoporosis in the postmenopausal women, hormone replacement therapy (HRT), perhaps the most effective treatment, is not preferred as it increases the risk of breast cancer and of cardiovascular diseases. The other available therapeutic agents are also associated with certain adverse effects. In this context, phytoestrogens are believed to play a role in maintaining or improving skeletal health. The present work reviews scientific information on medicinal plants which have already been documented for their antiosteoporotic activity. These plants may differ from each other in their mechanisms of action, they either bind with estrogen receptors which exhibit responses at the cellular and molecular levels, or in some cases they act by improving defense against oxidative stress\". The review which covers 18 plants briefly discusses their morphology, family, common name, phytoconstituents and proposed mechanism of action.","PeriodicalId":89634,"journal":{"name":"The Open bone journal","volume":"43 1","pages":"1-13"},"PeriodicalIF":0.0,"publicationDate":"2010-03-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"68144711","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 38

The Young's Modulus and Impact Energy Absorption of Wet and Dry Deer Cortical Bone 湿、干鹿皮质骨的杨氏模量和冲击能吸收

The Open bone journal Pub Date : 2009-10-27 DOI: 10.2174/1876525400901010038

J. Currey, T. Landete-Castillejos, J. Estevez, Augusto Olguín, Andres J. Garcia, L. Gallego

{"title":"The Young's Modulus and Impact Energy Absorption of Wet and Dry Deer Cortical Bone","authors":"J. Currey, T. Landete-Castillejos, J. Estevez, Augusto Olguín, Andres J. Garcia, L. Gallego","doi":"10.2174/1876525400901010038","DOIUrl":"https://doi.org/10.2174/1876525400901010038","url":null,"abstract":"We have shown recently that antlers of red deer, at the time that they are used in fights in the rut, are essentially dry. We have also shown that dry antler material has a lower impact energy absorption than that of wet antler, a property which, in a fight, is probably very important in the first clashing of antlers. However, dry antler has a much higher Young's modulus (stiffness) than wet antler, and this property will be important in the pushing match that follows the initial impact. These values were compared with those of wet bone, and it was found that although dry antler had a somewhat lower Young's modulus than wet bone, it had a much higher impact energy absorption. In that paper we did not consider the properties of dry bone. We now rectify that. The present paper compares the Young's modulus and impact energy absorption of wet and dry antler with that of wet and dry long bone of deer. It is found that the Young's modulus of dry antler is slightly less (12%) than that of wet long bone, which is in turn slightly less (7%) than that of dry long bone. On the other hand the impact energy absorption of dry antler is much (x6.6) greater than that of wet bone and even greater (x14.3) than that of dry bone. (The impact energy absorption of wet antler could not be measured consistently; it was certainly very high). We suggest that the material properties of antler (which is necessarily dry when used in fights) are superior to those of dry long bone material because, although they have somewhat lower (18%) Young's modulus, they have a much greater (x14) impact energy absorption. The properties of wet long bone and wet antler material are given for comparison, but neither could be used in reality.","PeriodicalId":89634,"journal":{"name":"The Open bone journal","volume":"1 1","pages":"38-45"},"PeriodicalIF":0.0,"publicationDate":"2009-10-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"68144702","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 21