Bioscience trends最新文献_第8页

Geriatric syndromes, chronic inflammation, and advances in the management of frailty: A review with new insights. 老年综合征、慢性炎症和虚弱治疗进展：一篇有新见解的综述。

IF 5.5 4区生物学

Bioscience trends Pub Date : 2023-09-15 Epub Date: 2023-08-23 DOI: 10.5582/bst.2023.01184

Niuniu Li, Gaolin Liu, Hong Gao, Qiang Wu, Juan Meng, Fei Wang, Siwei Jiang, Meixia Chen, Wenhui Xu, Yifan Zhang, Yanjun Wang, Yingqian Feng, Juncai Liu, Cheng Xu, Hongzhou Lu

{"title":"Geriatric syndromes, chronic inflammation, and advances in the management of frailty: A review with new insights.","authors":"Niuniu Li, Gaolin Liu, Hong Gao, Qiang Wu, Juan Meng, Fei Wang, Siwei Jiang, Meixia Chen, Wenhui Xu, Yifan Zhang, Yanjun Wang, Yingqian Feng, Juncai Liu, Cheng Xu, Hongzhou Lu","doi":"10.5582/bst.2023.01184","DOIUrl":"10.5582/bst.2023.01184","url":null,"abstract":"As people age, geriatric syndromes characterized by frailty significantly impact both clinical practice and public health. Aging weakens people's immune functions, leading to chronic low-grade inflammation that ultimately contributes to the development of frailty. Effectively managing geriatric syndromes and frailty can help alleviate the economic burden of an aging population. This review delves into the intricate relationship among aging, infection-induced inflammation, chronic inflammation, and frailty. In addition, it analyzes various approaches and interventions to address frailty, such as smart rehabilitation programs and stem-cell treatments, offering promising solutions in this new era. Given the importance of this topic, further research into the mechanisms of frailty is crucial. Equally essential is the devising of relevant measures to delay its onset and the formulation of comprehensive clinical, research, and public health strategies to enhance the quality of life for elderly individuals.","PeriodicalId":8957,"journal":{"name":"Bioscience trends","volume":"17 4","pages":"262-270"},"PeriodicalIF":5.5,"publicationDate":"2023-09-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10668309","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Impact of sarcopenia on S1 adjuvant chemotherapy and prognosis in pancreatic cancer patients. 少肌症对癌症患者S1辅助化疗和预后的影响。

IF 5.5 4区生物学

Bioscience trends Pub Date : 2023-09-15 Epub Date: 2023-08-29 DOI: 10.5582/bst.2023.01209

Kumi Takagi, Yosuke Inoue, Atsushi Oba, Yoshihiro Ono, Takafumi Sato, Hiromichi Ito, Yoko Saino, Akio Saiura, Yu Takahashi

{"title":"Impact of sarcopenia on S1 adjuvant chemotherapy and prognosis in pancreatic cancer patients.","authors":"Kumi Takagi, Yosuke Inoue, Atsushi Oba, Yoshihiro Ono, Takafumi Sato, Hiromichi Ito, Yoko Saino, Akio Saiura, Yu Takahashi","doi":"10.5582/bst.2023.01209","DOIUrl":"10.5582/bst.2023.01209","url":null,"abstract":"Although the importance of adjuvant chemotherapy (AC) has been recognized in pancreatic cancer (PC) patients, there are few studies to address the underlying mechanisms of failure to complete AC. This study aims to investigate the relationship between nutritional state represented by sarcopenia and failure to complete AC in patients after curative-intent surgery for PC. This study included 110 patients who underwent pancreaticoduodenectomy for potentially resectable pancreatic cancers with intention of adjuvant S-1. Sarcopenia was defined using the psoas muscle mass index with cutoff values of 6.36 cm2/m2 for men and 3.92 cm2/m2 for women, which were calculated with a 3-D volumetric software. The relation between sarcopenia and successful AC and long-term survival were investigated. Twenty-nine (26%) patients were diagnosed as having sarcopenia (Sarcopenia group). Sarcopenia group comprised significantly older patients than Non-sarcopenia group (72 vs. 67 years old, p = 0.0087). AC was successfully completed in 14 patients (48%) in Sarcopenia group compared to 72 patients (89%) in Non-sarcopenia group (p < 0.0001). Multivariate analysis identified age ≥ 70 years and sarcopenia as significant risk factors for failure of AC. Among patients ≥ 70 years old, rate of successful AC was significantly higher in sarcopenia groups than non-sarcopenia group (17% vs. 78%, p < 0.001). In conclusions, age and sarcopenia were critical risk factors for the failure of 6 months of adjuvant chemotherapy. Among elderly patients, sarcopenia can predict the poor success rate of AC.","PeriodicalId":8957,"journal":{"name":"Bioscience trends","volume":"17 4","pages":"310-317"},"PeriodicalIF":5.5,"publicationDate":"2023-09-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10668837","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Advances in deep learning: From diagnosis to treatment. 深度学习的进展:从诊断到治疗。

IF 5.5 4区生物学

Bioscience trends Pub Date : 2023-07-11 DOI: 10.5582/bst.2023.01148

Tianqi Huang, Longfei Ma, Boyu Zhang, Hongen Liao

{"title":"Advances in deep learning: From diagnosis to treatment.","authors":"Tianqi Huang, Longfei Ma, Boyu Zhang, Hongen Liao","doi":"10.5582/bst.2023.01148","DOIUrl":"https://doi.org/10.5582/bst.2023.01148","url":null,"abstract":"Deep learning has brought about a revolution in the field of medical diagnosis and treatment. The use of deep learning in healthcare has grown exponentially in recent years, achieving physician-level accuracy in various diagnostic tasks and supporting applications such as electronic health records and clinical voice assistants. The emergence of medical foundation models, as a new approach to deep learning, has greatly improved the reasoning ability of machines. Characterized by large training datasets, context awareness, and multi-domain applications, medical foundation models can integrate various forms of medical data to provide user-friendly outputs based on a patien's information. Medical foundation models have the potential to integrate current diagnostic and treatment systems, providing the ability to understand multi-modal diagnostic information and real-time reasoning ability in complex surgical scenarios. Future research on foundation model-based deep learning methods will focus more on the collaboration between physicians and machines. On the one hand, developing new deep learning methods will reduce the repetitive labor of physicians and compensate for shortcomings in their diagnostic and treatment capabilities. On the other hand, physicians need to embrace new deep learning technologies, comprehend the principles and technical risks of deep learning methods, and master the procedures for integrating them into clinical practice. Ultimately, the integration of artificial intelligence analysis with human decision-making will facilitate accurate personalized medical care and enhance the efficiency of physicians.","PeriodicalId":8957,"journal":{"name":"Bioscience trends","volume":"17 3","pages":"190-192"},"PeriodicalIF":5.5,"publicationDate":"2023-07-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9856781","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

EMG-FRNet: A feature reconstruction network for EMG irrelevant gesture recognition. EMG- frnet:用于肌电无关手势识别的特征重构网络。

IF 5.5 4区生物学

Bioscience trends Pub Date : 2023-07-11 DOI: 10.5582/bst.2023.01116

Wenli Zhang, Yufei Wang, Jianyi Zhang, Gongpeng Pang

{"title":"EMG-FRNet: A feature reconstruction network for EMG irrelevant gesture recognition.","authors":"Wenli Zhang, Yufei Wang, Jianyi Zhang, Gongpeng Pang","doi":"10.5582/bst.2023.01116","DOIUrl":"https://doi.org/10.5582/bst.2023.01116","url":null,"abstract":"With the development of deep learning technology, gesture recognition based on surface electromyography (EMG) signals has shown broad application prospects in various human-computer interaction fields. Most current gesture recognition technologies can achieve high recognition accuracy on a wide range of gesture actions. However, in practical applications, gesture recognition based on surface EMG signals is susceptible to interference from irrelevant gesture movements, which affects the accuracy and security of the system. Therefore, it is crucial to design an irrelevant gesture recognition method. This paper introduces the GANomaly network from the field of image anomaly detection into surface EMG-based irrelevant gesture recognition. The network has a small feature reconstruction error for target samples and a large feature reconstruction error for irrelevant samples. By comparing the relationship between the feature reconstruction error and the predefined threshold, we can determine whether the input samples are from the target category or the irrelevant category. In order to improve the performance of EMG irrelevant gesture recognition, this paper proposes a feature reconstruction network named EMG-FRNet for EMG irrelevant gesture recognition. This network is based on GANomaly and incorporates structures such as channel cropping (CC), cross-layer encoding-decoding feature fusion (CLEDFF), and SE channel attention (SE). In this paper, Ninapro DB1, Ninapro DB5 and self-collected datasets were used to verify the performance of the proposed model. The Area Under the receiver operating characteristic Curve (AUC) values of EMG-FRNet on the above three datasets were 0.940, 0.926 and 0.962, respectively. Experimental results demonstrate that the proposed model achieves the highest accuracy among related research.","PeriodicalId":8957,"journal":{"name":"Bioscience trends","volume":"17 3","pages":"219-229"},"PeriodicalIF":5.5,"publicationDate":"2023-07-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9856784","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Donor-recipient matching in adult liver transplantation: Current status and advances. 成人肝移植供体-受体匹配的现状与进展。

IF 5.5 4区生物学

Bioscience trends Pub Date : 2023-07-11 DOI: 10.5582/bst.2023.01076

Caterina Accardo, Ivan Vella, Duilio Pagano, Fabrizio di Francesco, Sergio Li Petri, Sergio Calamia, Pasquale Bonsignore, Alessandro Tropea, Salvatore Gruttadauria

引用次数: 0

The application and prospection of augmented reality in hepato-pancreato-biliary surgery. 增强现实技术在肝胆胰手术中的应用与展望。

IF 5.5 4区生物学

Bioscience trends Pub Date : 2023-07-11 DOI: 10.5582/bst.2023.01086

Junlong Dai, Weili Qi, Zhancheng Qiu, Chuan Li

{"title":"The application and prospection of augmented reality in hepato-pancreato-biliary surgery.","authors":"Junlong Dai, Weili Qi, Zhancheng Qiu, Chuan Li","doi":"10.5582/bst.2023.01086","DOIUrl":"https://doi.org/10.5582/bst.2023.01086","url":null,"abstract":"Augmented Reality (AR) is one of the main forms of Extended Reality (XR) application in surgery. hepato-pancreato-biliary (HPB) surgeons could benefit from AR as an efficient tool for making surgical plans, providing intraoperative navigation, and enhancing surgical skills. The introduction of AR to HPB surgery is less than 30 years but brings profound influence. From the early days of projecting liver models on patients' surfaces for locating a better puncture point to today's assisting surgeons to perform live donor liver transplantation, a series of successful clinical practices have proved that AR can play a constructive role in HPB surgery and has great potential. Thus far, AR has been shown to increase efficiency and safety in surgical resection, and, at the same time, can improve oncological outcomes and reduce surgical risk. Although AR has presented admitted advantages in surgery, AR's application is still immature as an emerging technique and needs more exploration. In this paper, we reviewed the principles of AR and its developing history in HPB surgery, describing its significant practical applications over the past 30 years. Reviewing the past attempts of AR in HPB surgery could make HPB surgeons a better understanding of future surgery and the digital trends in medicine. The routine uses of AR in HPB surgery, as an indication of the operating room entering the new era, is coming soon.","PeriodicalId":8957,"journal":{"name":"Bioscience trends","volume":"17 3","pages":"193-202"},"PeriodicalIF":5.5,"publicationDate":"2023-07-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10157949","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The ability of Segmenting Anything Model (SAM) to segment ultrasound images. 任意分割模型(SAM)分割超声图像的能力。

IF 5.5 4区生物学

Bioscience trends Pub Date : 2023-07-11 DOI: 10.5582/bst.2023.01128

Fang Chen, Lingyu Chen, Haojie Han, Sainan Zhang, Daoqiang Zhang, Hongen Liao

引用次数: 1

The potential of 'Segment Anything' (SAM) for universal intelligent ultrasound image guidance. “分段任何”(SAM)在通用智能超声图像引导中的潜力。

IF 5.5 4区生物学

Bioscience trends Pub Date : 2023-07-11 DOI: 10.5582/bst.2023.01119

Guochen Ning, Hanyin Liang, Zhongliang Jiang, Hui Zhang, Hongen Liao

引用次数: 3

The priority for prevention and control of infectious diseases: Reform of the Centers for Disease Prevention and Control - Occasioned by "the WHO chief declares end to COVID-19 as a global health emergency". 预防和控制传染病的优先事项:疾病预防和控制中心的改革——由“世卫组织总干事宣布COVID-19结束为全球卫生紧急事件”引发。

IF 5.5 4区生物学

Bioscience trends Pub Date : 2023-07-11 DOI: 10.5582/bst.2023.01124

Mingyu Luo, Fuzhe Gong, Jinna Wang, Zhenyu Gong

{"title":"The priority for prevention and control of infectious diseases: Reform of the Centers for Disease Prevention and Control - Occasioned by \"the WHO chief declares end to COVID-19 as a global health emergency\".","authors":"Mingyu Luo, Fuzhe Gong, Jinna Wang, Zhenyu Gong","doi":"10.5582/bst.2023.01124","DOIUrl":"https://doi.org/10.5582/bst.2023.01124","url":null,"abstract":"The novel coronavirus disease 2019 (COVID-19) pandemic has revealed that infectious diseases will present a significant worldwide threat for a long time in the future. Centers for Disease Prevention and Control (CDCs) worldwide have developed for nearly 80 years to fight against infectious disease and protect public health. However, at the advent of the 21th century, the responsibility for prevention and control of infectious diseases has gradually been marginalized in the CDC system. The COVID-19 pandemic has also provided a glimpse into the overburdened operational process and inadequate personnel reserve of the current system of CDCs. In addition, a long-term multisectoral joint mechanism has not been created for sharing information and cooperation to facilitate public health. Reform of the system of CDCs or public health is very necessary. A global prevention and control system should be envisioned and implemented worldwide, and vertical management should be implemented throughout all levels of CDCs to improve their structure and administrative status. The WHO should expand its scope of responsibilities, especially with regard to mechanisms for joint prevention and control of infectious diseases, to substantially implement the \"One Health\" concept. The International Health Regulations (IHR) and relevant laws and regulations should enshrine the CDC's authority in administration and policy-making to deal with outbreaks or pandemics of infectious diseases.","PeriodicalId":8957,"journal":{"name":"Bioscience trends","volume":"17 3","pages":"239-244"},"PeriodicalIF":5.5,"publicationDate":"2023-07-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10175490","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 17

Emerging infectious diseases never end: The fight continues. 新出现的传染病从未结束:斗争仍在继续。

IF 5.5 4区生物学

Bioscience trends Pub Date : 2023-07-11 DOI: 10.5582/bst.2023.01104

Yang Yang, Liping Guo, Hongzhou Lu

引用次数: 0