Bioscience trends最新文献_第10页

A cross-sectional study on the need for and utilization of assistive walking devices by people age 55 and older in Shanghai. 上海市55岁及以上老年人对辅助步行设备的需求和使用情况的横断面研究

IF 5.5 4区生物学

Bioscience trends Pub Date : 2023-05-15 DOI: 10.5582/bst.2022.01515

Wendi Cheng, Yifan Cao, Hua Wang, Xin Peng, Chunyan Xie, Changying Wang, Duo Chen, Lingshan Wan, Jia Xue, Yunwei Zhang, Hongyun Xin, Wei Zhuang, Hansheng Ding

{"title":"A cross-sectional study on the need for and utilization of assistive walking devices by people age 55 and older in Shanghai.","authors":"Wendi Cheng, Yifan Cao, Hua Wang, Xin Peng, Chunyan Xie, Changying Wang, Duo Chen, Lingshan Wan, Jia Xue, Yunwei Zhang, Hongyun Xin, Wei Zhuang, Hansheng Ding","doi":"10.5582/bst.2022.01515","DOIUrl":"https://doi.org/10.5582/bst.2022.01515","url":null,"abstract":"We conducted a study to analyze the unmet needs of and risk factors for use of assistive walking devices by the elderly based on sample survey data from Shanghai, China from July to October 2019. Among a total sample size of 11,193 people age 55 and older, 1,947 people (17.39%) needed assistive walking devices, 829 (42.58%) of whom needed but did not use those devices. Multivariate analysis indicated that residence, living alone or cohabitating, indoor handrails, the number of diseases, and IADL were factors influencing the unmet need for assistive walking devices (p < 0.05, respectively). People who lived in community health centers (p = 0.0104, OR = 1.956, 95% CI: 1.171-3.267) and those who lived only with their spouse (p = 0.0002, OR = 2.901, 95% CI: 1.641-5.126) were more likely to have an unmet need for assistive walking devices. People without indoor handrails (p = 0.0481, OR = 0.718, 95% CI: 0.517-0.997), those with 3 or more diseases (p = 0.0008, OR = 0.577, 95% CI: 0.418-0.796), and those with severely impaired IADL (p = 0.0002, OR = 0.139, 95% CI: 0.05-0.386) were less likely to have an unmet need for assistive walking devices. Self-perceived needs of the elderly, the diversity and performance of assistive devices, and the accessibility and affordability of assistive walking devices may lead to unmet needs.","PeriodicalId":8957,"journal":{"name":"Bioscience trends","volume":null,"pages":null},"PeriodicalIF":5.5,"publicationDate":"2023-05-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9458544","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Improving the sensitivity of liver tumor classification in ultrasound images via a power-law shot noise model. 利用幂律散粒噪声模型提高超声图像中肝脏肿瘤分类的灵敏度。

IF 5.5 4区生物学

Bioscience trends Pub Date : 2023-05-15 DOI: 10.5582/bst.2023.01040

Kenji Karako, Yuichiro Mihara, Kiyoshi Hasegawa, Yu Chen

引用次数: 0

Delayed gastric emptying after aggressive surgery for retroperitoneal sarcoma - Incidence, characteristics, and risk factors. 腹膜后肉瘤侵袭性手术后胃排空延迟-发生率、特征和危险因素。

IF 5.5 4区生物学

Bioscience trends Pub Date : 2023-03-11 DOI: 10.5582/bst.2022.01522

Ang Lv, Rongze Sun, Hui Qiu, Jianhui Wu, Xiuyun Tian, Chunyi Hao

{"title":"Delayed gastric emptying after aggressive surgery for retroperitoneal sarcoma - Incidence, characteristics, and risk factors.","authors":"Ang Lv, Rongze Sun, Hui Qiu, Jianhui Wu, Xiuyun Tian, Chunyi Hao","doi":"10.5582/bst.2022.01522","DOIUrl":"https://doi.org/10.5582/bst.2022.01522","url":null,"abstract":"Delayed gastric emptying (DGE) after aggressive resection of retroperitoneal sarcoma (RPS) has rarely been described. This study aimed to determine the incidence and characteristics of DGE after surgery for RPS and explore its potential risk factors. Patients with RPS who had undergone surgery between January 2010 and February 2021 were retrospectively analyzed. DGE was defined and graded according to the International Study Group of Pancreatic Surgery classification and classified as primary or secondary to other complications. Patients with clinically relevant DGE (crDGE, grade B+C) were compared to those with no or mild DGE (grade A). Multivariate logistic regression analysis of clinicopathological and surgical parameters was performed to identify risk factors for crDGE. Of the 239 patients studied, 69 (28.9%) had experienced DGE and 54 (22.6%) had experienced crDGE. Patients with primary and secondary DGE accounted approximately half and half. The most common concurrent complications included abdominal infection, postoperative pancreatic fistula, and abdominal bleeding. Patients with crDGE were more likely to have multifocal tumors and the liposarcoma subtype, with a larger tumor size, longer operating time, more resected organs, and a history of combined resection of the stomach, pancreas, small intestine, and/or colon. In multivariate analysis, the tumor size, operating time, and combined pancreatic resection were independent risk factors for crDGE. In conclusion, the current results indicated that approximately one-fourth of patients experienced DGE after aggressive surgery for RPS and that DGE was primary or secondary to other underlying conditions. A large tumor involving long, difficult surgery and combined pancreatic resection highly predicted the incidence of crDGE. The prevention and management of DGE remain challenging.","PeriodicalId":8957,"journal":{"name":"Bioscience trends","volume":null,"pages":null},"PeriodicalIF":5.5,"publicationDate":"2023-03-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9465358","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Pre-enriched saline gargle samples for detection of SARS-CoV-2. 用于检测SARS-CoV-2的预富集盐水含漱液样品。

IF 5.5 4区生物学

Bioscience trends Pub Date : 2023-03-11 DOI: 10.5582/bst.2022.01530

Peng Xu, Jing Chen, Chengchen Qian, Wenqiang Yu

引用次数: 0

Detecting latent tuberculosis infection with a breath test using mass spectrometer: A pilot cross-sectional study. 使用质谱仪检测呼吸试验的潜伏性结核感染:一项试点横断面研究。

IF 5.5 4区生物学

Bioscience trends Pub Date : 2023-03-11 DOI: 10.5582/bst.2022.01476

Liang Fu, Yong Feng, Tantan Ren, Min Yang, Qianting Yang, Yi Lin, Hui Zeng, Jiaohong Zhang, Lei Liu, Qingyun Li, Mengqi He, Peize Zhang, Haibin Chen, Guofang Deng

{"title":"Detecting latent tuberculosis infection with a breath test using mass spectrometer: A pilot cross-sectional study.","authors":"Liang Fu, Yong Feng, Tantan Ren, Min Yang, Qianting Yang, Yi Lin, Hui Zeng, Jiaohong Zhang, Lei Liu, Qingyun Li, Mengqi He, Peize Zhang, Haibin Chen, Guofang Deng","doi":"10.5582/bst.2022.01476","DOIUrl":"https://doi.org/10.5582/bst.2022.01476","url":null,"abstract":"Mycobacterium tuberculosis (M.tb) infects a quarter of the world's population and may progress to active tuberculosis (ATB). There is no gold standard for diagnosing latent tuberculosis infection (LTBI). Some immunodiagnostic tests are recommended to detect LTBI but can not distinguish ATB from LTBI. The breath test is useful for diagnosing ATB compared to healthy subjects but was never studied for LTBI. This proof-of-concept study (Chinese Clinical Trials Registry number: ChiCTR2200058346) was the first to explore a novel, rapid, and simple LTBI detection method via breath test on high-pressure photon ionization time-of-flight mass spectrometry (HPPI-TOFMS). The case group of LTBI subjects (n = 185) and the control group (n = 250), which included ATB subgroup (n = 121) and healthy control (HC) subgroup (n = 129), were enrolled. The LTBI detection model indicated that a breath test via HPPI-TOFMS could distinguish LTBI from the control with a sensitivity of 80.0% (95% CI: 67.6%, 92.4%) and a specificity of 80.8% (95% CI: 71.8%, 89.9%). Nevertheless, further intensive studies with a larger sample size are required for clinical application.","PeriodicalId":8957,"journal":{"name":"Bioscience trends","volume":null,"pages":null},"PeriodicalIF":5.5,"publicationDate":"2023-03-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9447932","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 2

Different clinical guidelines, common goal: To reduce COVID-19 mortality. 不同的临床指南，共同的目标:降低COVID-19死亡率。

IF 5.5 4区生物学

Bioscience trends Pub Date : 2023-03-11 DOI: 10.5582/bst.2023.01009

Liqin Sun, Jiaye Liu, Fang Zhao, Jun Chen, Hongzhou Lu

引用次数: 0

For COVID-19, what are the priorities of normalized prevention and control strategies? 针对新冠肺炎疫情，常态化防控战略的重点是什么?

IF 5.5 4区生物学

Bioscience trends Pub Date : 2023-03-11 DOI: 10.5582/bst.2023.01005

Mingyu Luo, Fuzhe Gong, Jimin Sun, Zhenyu Gong

{"title":"For COVID-19, what are the priorities of normalized prevention and control strategies?","authors":"Mingyu Luo, Fuzhe Gong, Jimin Sun, Zhenyu Gong","doi":"10.5582/bst.2023.01005","DOIUrl":"https://doi.org/10.5582/bst.2023.01005","url":null,"abstract":"The COVID-19 pandemic has ravaged the world for three years. Most countries have adjusted policies and strategies in response to the burden of COVID-19. The severity of COVID-19 seems to be diminishing as the case fatality rate has declined and the number of vaccinated people has increased markedly. Given the large population worldwide, we need to pay attention to the continuing COVID-19 burden. Globally, the number of cases remains at a certain level, and the number of cases is still increasing in China. We also need to deal with shortages of medical resources, antipyretics, and home nursing facilities. SARS-CoV-2 will coexist with humans for a long time, and predicting viral mutations and pandemic trends will be difficult. The reform of the whole public health system is imperative. A comprehensive surveillance system should be created to determine the proportion of various pathogens and to guard against mixed infections of respiratory infectious diseases. A comprehensive response mechanism, including preventive measures and medical treatments, should be created as soon as possible to monitor the status of the epidemic and to deal with the long-term health burden of SARS-CoV-2.","PeriodicalId":8957,"journal":{"name":"Bioscience trends","volume":null,"pages":null},"PeriodicalIF":5.5,"publicationDate":"2023-03-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9097189","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 2

RNA-binding proteins in metabolic-associated fatty liver disease (MAFLD): From mechanism to therapy. 代谢相关性脂肪肝（MAFLD）中的 RNA 结合蛋白：从机制到治疗

IF 5.5 4区生物学

Bioscience trends Pub Date : 2023-03-11 Epub Date: 2023-01-22 DOI: 10.5582/bst.2022.01473

Jiawei Xu, Xingyu Liu, Shuqin Wu, Deju Zhang, Xiao Liu, Panpan Xia, Jitao Ling, Kai Zheng, Minxuan Xu, Yunfeng Shen, Jing Zhang, Peng Yu

引用次数: 0

Simulation of SARS-CoV-2 epidemic trends in Tokyo considering vaccinations, virus mutations, government policies and PCR tests. 考虑疫苗接种、病毒突变、政府政策和PCR检测的东京SARS-CoV-2流行趋势模拟

IF 5.5 4区生物学

Bioscience trends Pub Date : 2023-03-11 DOI: 10.5582/bst.2023.01012

Jianing Chu, Hikaru Morikawa, Yu Chen

{"title":"Simulation of SARS-CoV-2 epidemic trends in Tokyo considering vaccinations, virus mutations, government policies and PCR tests.","authors":"Jianing Chu, Hikaru Morikawa, Yu Chen","doi":"10.5582/bst.2023.01012","DOIUrl":"https://doi.org/10.5582/bst.2023.01012","url":null,"abstract":"The eighth wave of COVID-19 infection in the Tokyo area has brought daily confirmed cases to a new higher level. This paper aims to explain the previous seven epidemic waves and forecast the eighth epidemic trend of the area using agent-based modeling and extended SEIR denotation. Four key considerations are investigated in this research, that are: 1. Vaccination, 2. Virus mutations, 3. Governmental policies and 4. PCR tests. Our study finds that the confirmed cases in the previous seven epidemic waves were only the tip of the iceberg. Using data prior to December 1 2022, the eighth wave is expected to hover high in December 2022 and January 2023. Our research pioneers in the simulation of antibody declination on an individual level. Comparing the simulated results, we find that the arrival of new epidemic waves are related to the decline in the number of antibody possessors, especially the sixth and the seventh epidemic waves. Our simulation also suggests that faced with low severe and death rates, PCR tests would not make much difference to reduce overall infections. In this case, maintaining PCR tests to a low level helps to reduce both social cost and public anxiety. However, if faced with the opposite case, PCR tests should be adjusted to a higher level to detect early infections. Such level of PCR tests should be compatible with available medical resources.","PeriodicalId":8957,"journal":{"name":"Bioscience trends","volume":null,"pages":null},"PeriodicalIF":5.5,"publicationDate":"2023-03-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9465355","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

The initiation, exploration, and development of hospital-based health technology assessment in China: 2005 ‒ 2022. 中国医院卫生技术评价的发起、探索与发展:2005 - 2022。

IF 5.5 4区生物学

Bioscience trends Pub Date : 2023-03-11 DOI: 10.5582/bst.2023.01013

Mi Tang, Xueyan Zhang, Ziping Ye, Lvfan Feng, Yan Yang, Zhiying Hou, Fei Bai, Xia Lin, Xinyu Liu, Hai Yang, Shanlian Hu, Peipei Song, Jiangjiang He

{"title":"The initiation, exploration, and development of hospital-based health technology assessment in China: 2005 ‒ 2022.","authors":"Mi Tang, Xueyan Zhang, Ziping Ye, Lvfan Feng, Yan Yang, Zhiying Hou, Fei Bai, Xia Lin, Xinyu Liu, Hai Yang, Shanlian Hu, Peipei Song, Jiangjiang He","doi":"10.5582/bst.2023.01013","DOIUrl":"https://doi.org/10.5582/bst.2023.01013","url":null,"abstract":"A hospital-based health technology assessment (HB-HTA) can provide the evidence needed to inform clinical decisions at the administrative level. With the implementation of a new round of medical and health care system reforms in China, such as the abolition of medical mark-ups, adoption of modern hospital management systems, reform of diagnosis related groups (DRGs) payment, and performance evaluations for public hospitals, medical institutions increasingly need HB-HTA. The development of HB-HTA in China can be divided into three phases: An initiation phase (2005-2014), a preliminary exploratory phase (2015-2017), and a rapid development phase (2018-present). HB-HTA has been used to manage medical consumables, medical devices, and medicines, but there are still problems and challenges in terms of concept recognition, the mode of development, and limited professionals and data. To promote and use HB-HTA in developing countries, we have identifies the development paths and recommendations for implementation based on a case study in China, which can be summarized as follows: enhancing the top-level design of HB-HTA, formulating HB-HTA guidelines, further promoting the main ideas of HB-HTA, concentrating on the training of evaluation personnel, establishing an HB-HTA network and paying attention to the flexibility of HB-HTA in the application process, and multi- stakeholder participation.","PeriodicalId":8957,"journal":{"name":"Bioscience trends","volume":null,"pages":null},"PeriodicalIF":5.5,"publicationDate":"2023-03-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9465359","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0