{"title":"Monoplane 3D reconstruction of mapping ablation catheters: a feasibility study.","authors":"P Fallavollita","doi":"10.2349/biij.6.2.e17","DOIUrl":"https://doi.org/10.2349/biij.6.2.e17","url":null,"abstract":"<p><strong>Purpose: </strong>Radiofrequency (RF) catheter ablation has transformed treatment for arrhythmias and has become first-line therapy for some tachycardias. The precise localization of the arrhythmogenic site and the positioning of the RF catheter over that site are problematic: they can impair the efficiency of the procedure and are time consuming (several hours). This study evaluates the feasibility of using only single plane C-arm images in order to estimate the 3D coordinates of RF catheter electrodes in a cardiac phase.</p><p><strong>Materials and methods: </strong>The method makes use of a priori 3D model of the RF mapping catheter assuming rigid body motion equations in order to estimate the 3D locations of the catheter tip-electrodes in single view C-arm fluoroscopy images. Validation is performed on both synthetic and clinical data using computer simulation models. The authors' monoplane reconstruction algorithm is applied to a 3D helix mimicking the shape of a catheter and undergoing solely rigid motion. Similarly, the authors test the feasibility of recovering nonrigid motion by applying their method on true 3D coordinates of 13 ventricular markers from a sheep's ventricle.</p><p><strong>Results: </strong>The results of this study showed that the proposed monoplane algorithm recovers rigid motion adequately when using the spatial positions of a catheter in six consecutive C-arm image frames yielding maximum 3D root mean squares errors of 4.3 mm. On the other hand, the suggested algorithm did not recover nonrigid motion precisely as suggested by a maximum 3D root mean square value of 8 mm.</p><p><strong>Conclusion: </strong>Since RF catheter electrodes are rigid structures, the authors conclude that there is promise in recovering the 3D coordinates of the electrodes when making use of only single view images. Future work will involve adding nonrigid motion equations to their algorithm, which will then be applied to actual clinical data.</p>","PeriodicalId":89331,"journal":{"name":"Biomedical imaging and intervention journal","volume":"6 2","pages":"e17"},"PeriodicalIF":0.0,"publicationDate":"2010-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.2349/biij.6.2.e17","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40108509","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Dual time point imaging of FDG PET/CT in a tuberculous spondylodiscitis.","authors":"Hr Abdul, N Abdul, Aj Nordin","doi":"10.2349/biij.6.2.e18","DOIUrl":"https://doi.org/10.2349/biij.6.2.e18","url":null,"abstract":"<p><p>Dual Time Point Imaging (DTPI) technique is a specialised protocol adopted in (18)F-Fluorodeoxyglucose (FDG) Positron Emission Tomography (PET) imaging. This technique is claimed to be useful in differentiating malignant and infective lesions. The authors adopted this technique in a patient diagnosed with tuberculous spondylodiscitis and psoas abscess which demonstrated higher Maximum Standardized Uptake Value (SUVmax) during initial scans as compared with those obtained on delayed scans. The SUVmax changes between the two time points are believed to be a valuable finding for chronic granulomatous infective lesions such as tuberculosis.</p>","PeriodicalId":89331,"journal":{"name":"Biomedical imaging and intervention journal","volume":"6 2","pages":"e18"},"PeriodicalIF":0.0,"publicationDate":"2010-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.2349/biij.6.2.e18","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40108510","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Multislice CT angiography in cardiac imaging: prospective ECG-gating or retrospective ECG-gating?","authors":"Z Sun","doi":"10.2349/biij.6.1.e4","DOIUrl":"10.2349/biij.6.1.e4","url":null,"abstract":"<p><p>With the advent of multislice CT more than a decade ago, multislice CT angiography has demonstrated a huge potential in the less invasive imaging of cardiovascular disease, especially in the diagnosis of coronary artery disease. The diagnostic accuracy of multislice CT angiography has been significantly augmented with the rapid technical developments ranging from the initial 4-slice, to the current 64-slice and 256 and 320-slice CT scanners. This is mainly demonstrated by the improved spatial and temporal resolution when compared to the earlier type of CT scanners. Traditionally, multislice CT angiography is acquired with retrospective ECG-gating with acquisition of volume data at the expense of increased radiation dose, since data is acquired at the entire cardiac cycle, although not all of them are used for postprocessing or reconstructions. Recently, there is an increasing trend of utilising prospective ECG-gating in cardiac imaging with latest multislice CT scanners (64 or more slices) with significant reduction of radiation dose when compared to retrospective ECG-gating method. However, there is some debate as to the diagnostic value of prospective ECG-gating in the diagnosis of coronary artery disease, despite its attractive ability to reduce radiation dose. This article will review the performance of retrospective ECG-gating in the diagnostic value of coronary artery disease, highlight the potential applications of prospective ECG-gating, and explore the future directions of multislice CT angiography in cardiac imaging.</p>","PeriodicalId":89331,"journal":{"name":"Biomedical imaging and intervention journal","volume":"6 1","pages":"e4"},"PeriodicalIF":0.0,"publicationDate":"2010-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3097791/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40109055","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Multislice CT angiography of the plantar arch.","authors":"L Field, Z Sun","doi":"10.2349/biij.6.1.e10","DOIUrl":"https://doi.org/10.2349/biij.6.1.e10","url":null,"abstract":"<p><p>The aim of this case report is to present a multislice computed tomography angiography (CTA) procedure for viewing the plantar arch. A CTA was requested to determine the vascular sufficiency of the plantar arch of a 64-year-old patient with necrotic and gangrenous toes. The patient had recently undergone a proximal wedge osteotomy procedure for correction of a hallux valgus deformity. A 16-detector row CT scanner with 1.25 mm slice thickness and 0.625 mm reconstruction interval was used to reconstruct multiplanar reformats, maximum intensity projections and three-dimensional volume rendered images of the foot in question in both arterial and venous phases to determine if pathology of the plantar arch was present. The 3D reconstructed images of CTA demonstrated a loss of continuity of the plantar arch between the first and third metatarsals. This case report shows the diagnostic value of multislice CTA, especially 3D visualisation in the assessment of peripheral vascular branches.</p>","PeriodicalId":89331,"journal":{"name":"Biomedical imaging and intervention journal","volume":"6 1","pages":"e10"},"PeriodicalIF":0.0,"publicationDate":"2010-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.2349/biij.6.1.e10","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40109056","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Leigh syndrome: MRI findings in two children.","authors":"Al Kartikasalwah, Ngu Lh","doi":"10.2349/biij.6.1.e6","DOIUrl":"https://doi.org/10.2349/biij.6.1.e6","url":null,"abstract":"<p><p>Leigh syndrome is a progressive neurodegenerative disorder of childhood. The symmetrical necrotic lesions in the basal ganglia and/or brainstem which appear as hyperintense lesions on T2-weighted MRI is characteristic and one of the essential diagnostic criteria. Recognising this MR imaging pattern in a child with neurological problems should prompt the clinician to investigate for Leigh syndrome. We present here two cases of Leigh syndrome due to different biochemical/genetic defects, and discuss the subtle differences in their MR neuroimaging features.</p>","PeriodicalId":89331,"journal":{"name":"Biomedical imaging and intervention journal","volume":"6 1","pages":"e6"},"PeriodicalIF":0.0,"publicationDate":"2010-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.2349/biij.6.1.e6","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40109038","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"A survey of digital radiography practice in four South African teaching hospitals: an illuminative study.","authors":"T Nyathi, Tf Chirwa, Dg van der Merwe","doi":"10.2349/biij.6.1.e5","DOIUrl":"https://doi.org/10.2349/biij.6.1.e5","url":null,"abstract":"<p><strong>Purpose: </strong>The purpose of this study was to assess radiographer familiarity and preferences with digital radiography in four teaching hospitals and thereafter make recommendations in line with the migration from screen film to digital radiography.</p><p><strong>Materials and methods: </strong>A questionnaire was designed to collect data from either qualified or student radiographers from four teaching hospitals. From the four teaching hospitals, there were a total of 205 potential respondents. Among other things, responses regarding experiences and preferences with digital radiography, quality control procedures, patient dose, advantages and disadvantages of digital radiography were sought. The information collected was based on self-reporting by the participants. The study is exploratory in nature and descriptive statistics were generated from the collected data using Microsoft Excel 2007 and StatsDirect software.</p><p><strong>Results: </strong>Sixty-three out of 205 (31%) radiographers from all the four radiology centers responded to the circulated questionnaire. Only 15% (8) of the qualified radiographers had 4 or more years of experience with digital radiography compared to 68% (36) for the same amount of experience with screen-film radiography. Sixty-one percent (38) of the participants had been exposed to digital radiography during their lectures while at university. A small proportion, 16% (10) of the respondents underwent formal training in quality control procedures on the digital X-ray units they were using. Slightly more than half (55%) of the participants felt it was easier for them to retake an image in digital radiography than in screen film radiography.</p><p><strong>Conclusion: </strong>The results of this survey showed that the participants are familiar with digital radiography and have embraced this relatively new technology as shown by the fact that they can identify both its advantages and disadvantages as applied to clinical practice. However, there are minimal quality control procedures specific to digital radiography being undertaken as such there is need for formal education, continuing education and manufacturer training with respect to quality control as institutions make the transition from conventional screen film radiology to digital radiology.</p>","PeriodicalId":89331,"journal":{"name":"Biomedical imaging and intervention journal","volume":"6 1","pages":"e5"},"PeriodicalIF":0.0,"publicationDate":"2010-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.2349/biij.6.1.e5","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40109037","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
O Nawawi, Mn Hazman, Bjj Abdullah, A Vijayananthan, J Manikam, S Mahadeva, Kl Goh
{"title":"Transarterial embolisation of hepatocellular carcinoma with doxorubicin-eluting beads: single centre early experience.","authors":"O Nawawi, Mn Hazman, Bjj Abdullah, A Vijayananthan, J Manikam, S Mahadeva, Kl Goh","doi":"10.2349/biij.6.1.e7","DOIUrl":"https://doi.org/10.2349/biij.6.1.e7","url":null,"abstract":"<p><strong>Purpose: </strong>This is a retrospective study to evaluate the results of our early experience of using doxorubicin eluting beads (DEB) to treat patients with early and intermediate hepatocellular carcinoma (HCC).</p><p><strong>Material and methods: </strong>A cohort of 19 patients (84.2% male; 15.8% female; mean age 59.2 years ± 11.0; range, 32-80 years) with documented HCC of size 1.8-10cm (mean, 4.0cm ± 1.8 ) undergoing DEB transarterial chembolisation (TACE) was reviewed. All patients had at least one image examination (multiphase computed tomography or magnetic resonance imaging) after embolisation.</p><p><strong>Results: </strong>A total of 32 procedures were performed. The objective response according to the European Association for the Study of the Liver criteria was 57.9% at 1-month, 42.8% at 6-month and 50.0% at 1-year follow up. There were 4 (21.1%) treatment-related complications (1 liver abscess, 2 pancreatitis and 1 tumour rupture) which resulted in 2 deaths. One death occurred 3 weeks after second embolisation, due to ruptured pancreatic pseudocyst, giving a 5.3% 30-day mortality rate. Another patient died 2 months after embolisation caused by tumour rupture. Eight patients received radiofrequency ablation after embolisation for residual or recurrent tumours. The 1-year survival rate in the DEB TACE only group was 80% while the 1- and 2-year survival rate in the group that received radiofrequency after DEB TACE was 85.7% and 100% respectively.</p><p><strong>Conclusion: </strong>DEB TACE is safe and effective in select group of patients. Survival may be improved when combined with other treatment modality.</p>","PeriodicalId":89331,"journal":{"name":"Biomedical imaging and intervention journal","volume":"6 1","pages":"e7"},"PeriodicalIF":0.0,"publicationDate":"2010-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.2349/biij.6.1.e7","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40109039","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"A visual tutorial on the synthesis of gold nanoparticles.","authors":"A Low, V Bansal","doi":"10.2349/biij.6.1.e9","DOIUrl":"https://doi.org/10.2349/biij.6.1.e9","url":null,"abstract":"<p><p>Many papers have been written on the synthesis of gold nanoparticles but very few included pictures of the process, and none of them used video to show the whole process of synthesis. This paper records the process of synthesis of gold nanoparticles using video clips. Every process from cleaning of glassware, an important step in the synthesis of metallic nanoparticles, to the dialysis process is shown. It also includes the preparation of aqua regia and the actual synthesis of gold nanoparticles. In some papers, the dialysis process was omitted, but in this paper, it is included to complete the whole process as it is being used for purification.</p>","PeriodicalId":89331,"journal":{"name":"Biomedical imaging and intervention journal","volume":"6 1","pages":"e9"},"PeriodicalIF":0.0,"publicationDate":"2010-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.2349/biij.6.1.e9","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40109040","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"A new method for experimental characterisation of scattered radiation in 64-slice CT scanner.","authors":"A Akbarzadeh, Mr Ay, H Ghadiri, S Sarkar, H Zaidi","doi":"10.2349/biij.6.1.e3","DOIUrl":"https://doi.org/10.2349/biij.6.1.e3","url":null,"abstract":"<p><strong>Purpose: </strong>The consummate 64-slice CT scanner that spawns a new generation of non-invasive diagnostic tool, however revolutionary, brings with it the incidental by-product that is scattered radiation. The extended detector aperture capability in the 64-slcie CT scanner allows the effects of scattered radiation to be more pronounced and therefore demands that the magnitude and spatial distribution of scatter component be addressed during the imaging process. To this end, corrective algorithms need to be formulated on a basis of a precise understanding of scatter distribution. Relative to a 64-slice CT scanner, here now a unique solution is based upon dedicated blockers operative within various detector rows, calculating scatter profiles and scatter to primary ratios (SPR).</p><p><strong>Materials and methods: </strong>A single dimension blocker array was installed beneath the collimator, and the extrapolated shadow area on the detectors revealed the scatter radiation after exposure. The experiment was conducted using a 64-slice CT scanner manufactured by GE Healthcare Technologies.</p><p><strong>Results: </strong>Variables such as tube voltage, phantom size and phantom-off centring on the scatter profile and the SPR was measured using the dedicated blocker method introduced above. When tube voltage is increased from 80kVp to 140kVp in a 21.5 cm water phantom, the SPR is found to reduce from 219.9 to 39.9 respectively.</p><p><strong>Conclusion: </strong>The method developed within this study is applicable to any measurement and is direct with minimal complexity.</p>","PeriodicalId":89331,"journal":{"name":"Biomedical imaging and intervention journal","volume":"6 1","pages":"e3"},"PeriodicalIF":0.0,"publicationDate":"2010-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.2349/biij.6.1.e3","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40109053","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}