Biomedical imaging and intervention journal最新文献

{"title":"Evaluation of dose coverage to target volume and normal tissue sparing in the adjuvant radiotherapy of gastric cancers: 3D-CRT compared with dynamic IMRT.","authors":"Kk Murthy,&nbsp;Ka Shukeili,&nbsp;Ss Kumar,&nbsp;Ca Davis,&nbsp;Rr Chandran,&nbsp;S Namrata","doi":"10.2349/biij.6.3.e29","DOIUrl":"https://doi.org/10.2349/biij.6.3.e29","url":null,"abstract":"<p><strong>Purpose: </strong>To assess the potential advantage of intensity-modulated radiotherapy (IMRT) over 3D-conformal radiotherapy (3D-CRT) planning in postoperative adjuvant radiotherapy for patients with gastric carcinoma.</p><p><strong>Methods and materials: </strong>In a retrospective study, for plan comparison, dose distribution was recalculated in 15 patients treated with 3D-CRT on the contoured structures of same CT images using an IMRT technique. 3D-conformal plans with three fields and four-fields were compared with seven-field dynamic IMRT plans. The different plans were compared by analyzing the dose coverage of planning target volume using TV(95), D(mean), uniformity index, conformity index and homogeneity index parameters. To assess critical organ sparing, D(mean), D(max), dose to one-third and two-third volumes of the OARs and percentage of volumes receiving more than their tolerance doses were compared.</p><p><strong>Results: </strong>The average dose coverage values of PTV with 3F-CRT and 4F-CRT plans were comparable, where as IMRT plans achieved better target coverage(p<0.001) with higher conformity index value of 0.81±0.07 compared to both the 3D-CRT plans. The doses to the liver and bowel reduced significantly (p<0.001) with IMRT plans compared to other 3D-CRT plans. For all OARs the percentage of volumes receiving more than their tolerance doses were reduced with the IMRT plans.</p><p><strong>Conclusion: </strong>This study showed that a better target coverage and significant dose reduction to OARs could be achieved with the IMRT plans. The IMRT can be preferred with caution for organ motion. The authors are currently studying organ motion in the upper abdomen to use IMRT for patient treatment.</p>","PeriodicalId":89331,"journal":{"name":"Biomedical imaging and intervention journal","volume":"6 3","pages":"e29"},"PeriodicalIF":0.0,"publicationDate":"2010-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.2349/biij.6.3.e29","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40107080","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Left main renal artery entrapment by diaphragmatic crura: spiral CT angiography.","authors":"S Singham,&nbsp;P Murugasu,&nbsp;J Macintosh,&nbsp;P Murugasu,&nbsp;A Deshpande","doi":"10.2349/biij.6.2.e11","DOIUrl":"https://doi.org/10.2349/biij.6.2.e11","url":null,"abstract":"<p><p>Entrapment of renal artery by the diaphragmatic crus is a rare cause of renal artery stenosis. Spiral computed tomography angiography provides a definitive diagnosis and shows the precise relationship of the artery to the diaphragmatic crus. The authors present a case of hypertension developing in a young 20-year-old female due to entrapment of the left renal artery by the diaphragmatic crus. This condition should be considered in young hypertensive patients with renal artery stenosis without cardiovascular risk factors.</p>","PeriodicalId":89331,"journal":{"name":"Biomedical imaging and intervention journal","volume":"6 2","pages":"e11"},"PeriodicalIF":0.0,"publicationDate":"2010-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.2349/biij.6.2.e11","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40107947","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Magnetic resonance-guided focused ultrasound surgery (MRgFUS) treatment for uterine fibroids.","authors":"Bjj Abdullah,&nbsp;Rv Subramaniam,&nbsp;Ss Omar,&nbsp;P Wragg,&nbsp;N Ramli,&nbsp;Al Wui,&nbsp;Cc Lee,&nbsp;Y Yusof","doi":"10.2349/biij.6.2.e15","DOIUrl":"https://doi.org/10.2349/biij.6.2.e15","url":null,"abstract":"<p><p>Magnetic Resonance-guided focused Ultrasound Surgery (MRgFUS) is gaining popularity as an alternative to medical and surgical interventions in the management of symptomatic uterine fibroids. Studies have shown that it is an effective non-invasive treatment with minimal associated risks as compared to myomectomy and hysterectomy. MRgFUS can be offered to a majority of patients suffering from symptomatic uterine fibroids. It has been suggested that the use of broader inclusion criteria as well as the mitigation techniques makes it possible to offer MRgFUS to a much larger subset of patients than previously believed. This paper will describe how MRgFUS treatment for uterine fibroids is performed at the University of Malaya Medical Centre, Kuala Lumpur, Malaysia.</p>","PeriodicalId":89331,"journal":{"name":"Biomedical imaging and intervention journal","volume":"6 2","pages":"e15"},"PeriodicalIF":0.0,"publicationDate":"2010-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.2349/biij.6.2.e15","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40107950","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Development and use of iron oxide nanoparticles (part 2): The application of iron oxide contrast agents in MRI","authors":"G. Mandarano, J. Lodhia, P. Eu, N. Ferris, R. Davidson, S. Cowell","doi":"10.2349/BIIJ.6.2.E13","DOIUrl":"https://doi.org/10.2349/BIIJ.6.2.E13","url":null,"abstract":"","PeriodicalId":89331,"journal":{"name":"Biomedical imaging and intervention journal","volume":"6 1","pages":"1-14"},"PeriodicalIF":0.0,"publicationDate":"2010-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"68770931","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Business of medicine.","authors":"Bjj Abdullah","doi":"10.2349/biij.6.2.e14","DOIUrl":"https://doi.org/10.2349/biij.6.2.e14","url":null,"abstract":"As has often been said, people get set in their ways of thinking, living and believing until they are unable to see situations in ways other than what they are used to. Their brains just refuse to change its paradigm of thinking. For me, I have always thought of business in a certain way. Firstly, I was never really exposed to the concept of business, going as far back as I can remember. My father always reminded me that you should devote yourself to helping others for the overall good of society. So it should not come as a surprise that all my siblings work in the public service. When I started to work in the public sector serving a tertiary university hospital, the concept of pushing oneself for money or profit was considered \" dirty \" , even to the point of viewing such individuals as lower life forms! But over the last several years, while managing a department and pursuing an MBA, one question has been popping up in my mind: \" What business are doctors in? \" Is it about treating patients to help them recover from whatever ails them, no matter the cost to the society at large? Or is it about providing a patient a limb prosthesis even though he or she cannot afford to pay for it? What about keeping the public healthy first so they do not get sick, and saving all that money and technology? Are we not supposed to provide parking bays for our patients so they will not be driving around in circles while we literally drive into our offices? Is it about protecting one's discipline against the onslaught of the invaders? Is it about living in our little silos which, incidentally, were artificially created for an era long gone by? Is it about the need to ensure the maximum amount of resources no matter how it is used? Is it about being the first to get all the fancy high-tech gadgets and equipment? Is it about meeting all the performance targets set by the hospital or health authority? Should the insurance industry set guidelines for patients who need treatment? Should the vendors of imaging equipment and drugs be allowed to promote their products only with limited indications? Are they also acting ethically when they lobby the governments to pay for some of these new choices? If all these questions …","PeriodicalId":89331,"journal":{"name":"Biomedical imaging and intervention journal","volume":"6 2","pages":"e14"},"PeriodicalIF":0.0,"publicationDate":"2010-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.2349/biij.6.2.e14","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40107949","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Musculoskeletal MRI protocol.","authors":"Sp Tan,&nbsp;A Suraya,&nbsp;S Sa'don,&nbsp;A Ruzi,&nbsp;M Zahiah","doi":"10.2349/biij.6.2.e16","DOIUrl":"https://doi.org/10.2349/biij.6.2.e16","url":null,"abstract":"<p><p>The authors propose a musculoskeletal (MSK) magnetic resonance imaging (MRI) protocol using selected sequences for common orthopaedic indications. Selected sequences allow optimal visualisation of the indicated pathology while screening for other common conditions. The authors emphasise the need for standard positioning of the patient and standard orientation of scan planes to facilitate comparison with follow-up scans.</p>","PeriodicalId":89331,"journal":{"name":"Biomedical imaging and intervention journal","volume":"6 2","pages":"e16"},"PeriodicalIF":0.0,"publicationDate":"2010-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.2349/biij.6.2.e16","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40107951","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Dose verification of helical tomotherapy intensity modulated radiation therapy planning using 2D-array ion chambers.","authors":"S Xu,&nbsp;C Xie,&nbsp;Z Ju,&nbsp;X Dai,&nbsp;H Gong,&nbsp;L Wang,&nbsp;J Yang","doi":"10.2349/biij.6.2.e24","DOIUrl":"https://doi.org/10.2349/biij.6.2.e24","url":null,"abstract":"<p><strong>Purpose: </strong>To investigate the clinical usage of dose verification of Helical Tomotherapy plans by using 2D-array ion chambers, and to develop an efficient way to validate the dose delivered for the patients during treatments.</p><p><strong>Materials and methods: </strong>A pixel-segmented ionisation chamber device, IMRT MatriXX™ and Multicube™ phantom from IBA were used on ten selected Tomotherapy IMRT/IGRT head and neck plans in this study. The combined phantom was set up to measure the dose distribution from coronal and sagittal planes. The setup of phantom was guided for verifying the correction position by pre-treatment Tomotherapy MVCT images. After the irradiation, the measured dose distributions of coronal and sagittal planes were compared with those from calculation by the planning system for cross verification. The results were evaluated by the absolute and relative doses as well as Gamma (γ) function. The feasibility of the different measuring methods was studied for this rotational treatment technique.</p><p><strong>Results: </strong>The dose distributions measured by the MatriXX 2D array were in good agreements with plans calculated by Tomotherapy planning system. The discrepancy between the measured dose and predicted dose in the selected points was within ±3%. In the comparison of the pixel-segmented ionisation chamber versus treatment planning system using the 3 mm/3% γ-function criteria, the mean passing rates of 2 mm dose grid with γ-parameter ≤1 were 97.37% and 96.91%, in two orthogonal planes (coronal and sagittal directions), respectively.</p><p><strong>Conclusion: </strong>MatriXX with Multicube is a new system created for rotational delivery quality assurance (QA) and found to be reliable to measure both absolute dose and relative dose distributions, simultaneously. It achieves the goal of an efficient and accurate dosimetry validation method of the helical delivery pattern for the Helical Tomotherapy IMRT planning.</p>","PeriodicalId":89331,"journal":{"name":"Biomedical imaging and intervention journal","volume":"6 2","pages":"e24"},"PeriodicalIF":0.0,"publicationDate":"2010-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.2349/biij.6.2.e24","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40108511","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Uncomplicated term vaginal delivery following magnetic resonance-guided focused ultrasound surgery for uterine fibroids.","authors":"S Zaher,&nbsp;D Lyons,&nbsp;L Regan","doi":"10.2349/biij.6.2.e28","DOIUrl":"https://doi.org/10.2349/biij.6.2.e28","url":null,"abstract":"<p><p>A 35 year-old para 1+0 underwent MRgFUS per study protocol for multiple uterine fibroids, the largest of which measured 5 cm. She conceived 10 months following the procedure. The patient was induced at 41+6 weeks and underwent a normal vaginal delivery.</p>","PeriodicalId":89331,"journal":{"name":"Biomedical imaging and intervention journal","volume":"6 2","pages":"e28"},"PeriodicalIF":0.0,"publicationDate":"2010-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.2349/biij.6.2.e28","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40108512","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Are scientific journals touting for business","authors":"Martin Caon","doi":"10.2349/BIIJ.6.2.E20","DOIUrl":"https://doi.org/10.2349/BIIJ.6.2.E20","url":null,"abstract":"","PeriodicalId":89331,"journal":{"name":"Biomedical imaging and intervention journal","volume":"6 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2010-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"68770943","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Development and use of iron oxide nanoparticles (Part 1): Synthesis of iron oxide nanoparticles for MRI.","authors":"J Lodhia,&nbsp;G Mandarano,&nbsp;Nj Ferris,&nbsp;P Eu,&nbsp;Sf Cowell","doi":"10.2349/biij.6.2.e12","DOIUrl":"https://doi.org/10.2349/biij.6.2.e12","url":null,"abstract":"<p><p>Contrast agents, such as iron oxide, enhance MR images by altering the relaxation times of tissues in which the agent is present. They can also be used to label targeted molecular imaging probes. Unfortunately, no molecular imaging probe is currently available on the clinical MRI market. A promising platform for MRI contrast agent development is nanotechnology, where superparamagnetic iron oxide nanoparticles (SPIONS) are tailored for MR contrast enhancement, and/or for molecular imaging. SPIONs can be produced using a range of methods and the choice of method will be influenced by the characteristics most important for a particular application. In addition, the ability to attach molecular markers to SPIONS heralds their application in molecular imaging.There are many reviews on SPION synthesis for MRI; however, these tend to be targeted to a chemistry audience. The development of MRI contrast agents attracts experienced researchers from many fields including some researchers with little knowledge of medical imaging or MRI. This situation presents medical radiation practitioners with opportunities for involvement, collaboration or leadership in research depending on their level of commitment and their ability to learn. Medical radiation practitioners already possess a large portion of the understanding, knowledge and skills necessary for involvement in MRI development and molecular imaging. Their expertise in imaging technology, patient care and radiation safety provides them with skills that are directly applicable to research on the development and application of SPIONs and MRI.In this paper we argue that MRI SPIONs, currently limited to major research centres, will have widespread clinical use in the future. We believe that knowledge about this growing area of research provides an opportunity for medical radiation practitioners to enhance their specialised expertise to ensure best practice in a truly multi-disciplinary environment. This review outlines how and why SPIONs can be synthesised and examines their characteristics and limitations in the context of MR imaging.</p>","PeriodicalId":89331,"journal":{"name":"Biomedical imaging and intervention journal","volume":"6 2","pages":"e12"},"PeriodicalIF":0.0,"publicationDate":"2010-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.2349/biij.6.2.e12","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40107948","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}