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Ketamine Rescues Anhedonia by Cell-Type and Input Specific Adaptations in the Nucleus Accumbens 氯胺酮通过细胞类型和输入特异性适应在伏隔核中拯救快感缺乏症
IF 9.6 1区 医学
Biological Psychiatry Pub Date : 2025-04-09 DOI: 10.1016/j.biopsych.2025.02.059
Federica Lucantonio , Shuwen Li , Jacob Roeglin , Jaden Lu , Aleesha Shi , Katherine Czerpaniak , Francesca R. Fiocchi , Leonardo Bontempi , Brenda C. Shields , Carlos A. Zarate Jr. , Michael R. Tadross , Marco Pignatelli
{"title":"Ketamine Rescues Anhedonia by Cell-Type and Input Specific Adaptations in the Nucleus Accumbens","authors":"Federica Lucantonio , Shuwen Li , Jacob Roeglin , Jaden Lu , Aleesha Shi , Katherine Czerpaniak , Francesca R. Fiocchi , Leonardo Bontempi , Brenda C. Shields , Carlos A. Zarate Jr. , Michael R. Tadross , Marco Pignatelli","doi":"10.1016/j.biopsych.2025.02.059","DOIUrl":"10.1016/j.biopsych.2025.02.059","url":null,"abstract":"","PeriodicalId":8918,"journal":{"name":"Biological Psychiatry","volume":"97 9","pages":"Page S19"},"PeriodicalIF":9.6,"publicationDate":"2025-04-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143799431","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Longitudinal Trajectories of Symptom Change During Antidepressant Treatment Among Managed Care Patients With Depression and Anxiety 抑郁和焦虑管理护理患者抗抑郁药物治疗期间症状变化的纵向轨迹
IF 9.6 1区 医学
Biological Psychiatry Pub Date : 2025-04-09 DOI: 10.1016/j.biopsych.2025.02.041
Jyotishman Pathak , Judith Cukor , Veer Vekaria , Zhenxing Xu , Fei Wang , Mark Olfson , Samprit Banerjee , Gregory Simon , George Alexopoulos
{"title":"Longitudinal Trajectories of Symptom Change During Antidepressant Treatment Among Managed Care Patients With Depression and Anxiety","authors":"Jyotishman Pathak , Judith Cukor , Veer Vekaria , Zhenxing Xu , Fei Wang , Mark Olfson , Samprit Banerjee , Gregory Simon , George Alexopoulos","doi":"10.1016/j.biopsych.2025.02.041","DOIUrl":"10.1016/j.biopsych.2025.02.041","url":null,"abstract":"","PeriodicalId":8918,"journal":{"name":"Biological Psychiatry","volume":"97 9","pages":"Page S11"},"PeriodicalIF":9.6,"publicationDate":"2025-04-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143799442","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Precision TMS in Major Depressive Disorder: An Open-Label Trial of Personalized TMS 精确经颅磁刺激治疗重度抑郁症：一项个性化经颅磁刺激的开放标签试验
IF 9.6 1区 医学
Biological Psychiatry Pub Date : 2025-04-09 DOI: 10.1016/j.biopsych.2025.02.073
Luke Hearne , Lachlan Webb , Robin Cash , Conor Robinson , Philip Mosley , Joanna Ng , Simon Thwaites , Simon Issa , Jessica Miller , Andrew Zalesky , Bjorn Burgher , Luca Cocchi
{"title":"Precision TMS in Major Depressive Disorder: An Open-Label Trial of Personalized TMS","authors":"Luke Hearne , Lachlan Webb , Robin Cash , Conor Robinson , Philip Mosley , Joanna Ng , Simon Thwaites , Simon Issa , Jessica Miller , Andrew Zalesky , Bjorn Burgher , Luca Cocchi","doi":"10.1016/j.biopsych.2025.02.073","DOIUrl":"10.1016/j.biopsych.2025.02.073","url":null,"abstract":"","PeriodicalId":8918,"journal":{"name":"Biological Psychiatry","volume":"97 9","pages":"Pages S23-S24"},"PeriodicalIF":9.6,"publicationDate":"2025-04-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143798604","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Immune Cell-Specific Gene Expression Profiles in Major Depressive Disorder and Links to Motivation for Reward 重性抑郁症的免疫细胞特异性基因表达谱及其与奖励动机的联系
IF 9.6 1区 医学
Biological Psychiatry Pub Date : 2025-04-09 DOI: 10.1016/j.biopsych.2025.02.065
James Murrough , Flurin Cathomas , Sara Costi , Giada Dirupo , Aarthi Ramakrishnan , Lyonna Parise , Kenny Chan , Li Shen , Laurel Morris , Scott Russo
{"title":"Immune Cell-Specific Gene Expression Profiles in Major Depressive Disorder and Links to Motivation for Reward","authors":"James Murrough , Flurin Cathomas , Sara Costi , Giada Dirupo , Aarthi Ramakrishnan , Lyonna Parise , Kenny Chan , Li Shen , Laurel Morris , Scott Russo","doi":"10.1016/j.biopsych.2025.02.065","DOIUrl":"10.1016/j.biopsych.2025.02.065","url":null,"abstract":"","PeriodicalId":8918,"journal":{"name":"Biological Psychiatry","volume":"97 9","pages":"Page S21"},"PeriodicalIF":9.6,"publicationDate":"2025-04-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143799176","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Ketamine's Impact on Excitatory and Inhibitory Activity in the mPFC: Biphasic Recruitment of GABA Function in Antidepressant-Like Responses 氯胺酮对mPFC兴奋性和抑制活性的影响：抗抑郁样反应中GABA功能的双相募集
IF 9.6 1区 医学
Biological Psychiatry Pub Date : 2025-04-09 DOI: 10.1016/j.biopsych.2025.02.060
Manoela Fogaca , Fernanda Daher , Marina Picciotto
{"title":"Ketamine's Impact on Excitatory and Inhibitory Activity in the mPFC: Biphasic Recruitment of GABA Function in Antidepressant-Like Responses","authors":"Manoela Fogaca , Fernanda Daher , Marina Picciotto","doi":"10.1016/j.biopsych.2025.02.060","DOIUrl":"10.1016/j.biopsych.2025.02.060","url":null,"abstract":"","PeriodicalId":8918,"journal":{"name":"Biological Psychiatry","volume":"97 9","pages":"Page S19"},"PeriodicalIF":9.6,"publicationDate":"2025-04-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143799336","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Antidepressant Properties of Ketamine in a Cellular Model System: Nmdar Independence and a Role for Camp 氯胺酮在细胞模型系统中的抗抑郁特性：Nmdar独立性和Camp的作用
IF 9.6 1区 医学
Biological Psychiatry Pub Date : 2025-04-09 DOI: 10.1016/j.biopsych.2025.02.058
Jeff Schappi , Mei Ao , Aksu Gunay , Mark Rasenick
{"title":"Antidepressant Properties of Ketamine in a Cellular Model System: Nmdar Independence and a Role for Camp","authors":"Jeff Schappi , Mei Ao , Aksu Gunay , Mark Rasenick","doi":"10.1016/j.biopsych.2025.02.058","DOIUrl":"10.1016/j.biopsych.2025.02.058","url":null,"abstract":"","PeriodicalId":8918,"journal":{"name":"Biological Psychiatry","volume":"97 9","pages":"Pages S18-S19"},"PeriodicalIF":9.6,"publicationDate":"2025-04-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143799430","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Effect of Antidepressant Treatment on 5-HT4 Receptor Binding and Associations With Clinical Outcomes and Verbal Memory in Major Depressive Disorder 抗抑郁药物治疗对重度抑郁症患者5-HT4受体结合的影响及其与临床结局和言语记忆的关系
IF 9.6 1区 医学
Biological Psychiatry Pub Date : 2025-04-09 DOI: 10.1016/j.biopsych.2025.02.093
Vibeke Dam , Kristin Kohler-Forsberg , Brice Ozenne , Søren V. Larsen , Chen Teng Ip , Anders Jørgensen , Dea S. Stenbæk , Jacob Madsen , Claus Svarer , Martin Balslev-Jørgensen , Gitte M. Knudsen , Vibe Frokjaer
{"title":"Effect of Antidepressant Treatment on 5-HT4 Receptor Binding and Associations With Clinical Outcomes and Verbal Memory in Major Depressive Disorder","authors":"Vibeke Dam , Kristin Kohler-Forsberg , Brice Ozenne , Søren V. Larsen , Chen Teng Ip , Anders Jørgensen , Dea S. Stenbæk , Jacob Madsen , Claus Svarer , Martin Balslev-Jørgensen , Gitte M. Knudsen , Vibe Frokjaer","doi":"10.1016/j.biopsych.2025.02.093","DOIUrl":"10.1016/j.biopsych.2025.02.093","url":null,"abstract":"","PeriodicalId":8918,"journal":{"name":"Biological Psychiatry","volume":"97 9","pages":"Pages S31-S32"},"PeriodicalIF":9.6,"publicationDate":"2025-04-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143799450","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Predicting Involuntary Admission Following Inpatient Psychiatric Treatment Using Machine Learning Trained on Electronic Health Record Data 使用电子健康记录数据训练的机器学习预测住院精神病治疗后的非自愿入院
IF 9.6 1区 医学
Biological Psychiatry Pub Date : 2025-04-09 DOI: 10.1016/j.biopsych.2025.02.047
Erik Perfalk , Jakob Grøhn Damgaard , Martin Bernstorff , Lasse Hansen , Andreas Aalkjær Danielsen , Søren Dinesen Østergaard
{"title":"Predicting Involuntary Admission Following Inpatient Psychiatric Treatment Using Machine Learning Trained on Electronic Health Record Data","authors":"Erik Perfalk , Jakob Grøhn Damgaard , Martin Bernstorff , Lasse Hansen , Andreas Aalkjær Danielsen , Søren Dinesen Østergaard","doi":"10.1016/j.biopsych.2025.02.047","DOIUrl":"10.1016/j.biopsych.2025.02.047","url":null,"abstract":"","PeriodicalId":8918,"journal":{"name":"Biological Psychiatry","volume":"97 9","pages":"Page S14"},"PeriodicalIF":9.6,"publicationDate":"2025-04-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143799539","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Basal Ganglia Indirect Pathway Dysfunction in Maladaptive Repetitive Behaviours: New Insights From Preclinical Models to Drive New Therapies 基底神经节间接通路功能障碍在不适应重复行为：从临床前模型驱动新疗法的新见解
IF 9.6 1区 医学
Biological Psychiatry Pub Date : 2025-04-09 DOI: 10.1016/j.biopsych.2025.02.072
Aidan Price , Isabel Chew , Elizabeth Manning
{"title":"Basal Ganglia Indirect Pathway Dysfunction in Maladaptive Repetitive Behaviours: New Insights From Preclinical Models to Drive New Therapies","authors":"Aidan Price , Isabel Chew , Elizabeth Manning","doi":"10.1016/j.biopsych.2025.02.072","DOIUrl":"10.1016/j.biopsych.2025.02.072","url":null,"abstract":"","PeriodicalId":8918,"journal":{"name":"Biological Psychiatry","volume":"97 9","pages":"Page S23"},"PeriodicalIF":9.6,"publicationDate":"2025-04-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143799544","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Smart Trial to Boost Antidepressant Response in Major Depression 提高重度抑郁症患者抗抑郁反应的明智试验
IF 9.6 1区 医学
Biological Psychiatry Pub Date : 2025-04-09 DOI: 10.1016/j.biopsych.2025.02.037
Diego Pizzagalli , Manuel Kuhn , Peter Zhukovsky , Sarah Woronko , Li Mohan , Ethan Zhang , Tracy Lam , Lauren Borchers , Boyu Ren
{"title":"Smart Trial to Boost Antidepressant Response in Major Depression","authors":"Diego Pizzagalli , Manuel Kuhn , Peter Zhukovsky , Sarah Woronko , Li Mohan , Ethan Zhang , Tracy Lam , Lauren Borchers , Boyu Ren","doi":"10.1016/j.biopsych.2025.02.037","DOIUrl":"10.1016/j.biopsych.2025.02.037","url":null,"abstract":"","PeriodicalId":8918,"journal":{"name":"Biological Psychiatry","volume":"97 9","pages":"Pages S9-S10"},"PeriodicalIF":9.6,"publicationDate":"2025-04-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143799629","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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