{"title":"Adult Hippocampal Neurogenesis and the Landscape of Plasticity in the Human Brain","authors":"Chloe E. Page , David A. Ross","doi":"10.1016/j.biopsych.2024.12.018","DOIUrl":"10.1016/j.biopsych.2024.12.018","url":null,"abstract":"","PeriodicalId":8918,"journal":{"name":"Biological Psychiatry","volume":"97 6","pages":"Pages 558-560"},"PeriodicalIF":9.6,"publicationDate":"2025-02-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143428723","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Few but Not Futile: A Sparse Nucleus Accumbens Corticotropin-Releasing Factor Population Regulates Reward Learning","authors":"Alison V. Roland","doi":"10.1016/j.biopsych.2025.01.004","DOIUrl":"10.1016/j.biopsych.2025.01.004","url":null,"abstract":"","PeriodicalId":8918,"journal":{"name":"Biological Psychiatry","volume":"97 6","pages":"Pages 561-562"},"PeriodicalIF":9.6,"publicationDate":"2025-02-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143428724","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Ana Stijovic, Paul Forbes, Ekaterina Pronizius, Anja Feneberg, Giulio Piperno, Urs M Nater, Claus Lamm, Giorgia Silani
{"title":"Affective and Social Predictors of Food Consumption During the COVID-19 Lockdown.","authors":"Ana Stijovic, Paul Forbes, Ekaterina Pronizius, Anja Feneberg, Giulio Piperno, Urs M Nater, Claus Lamm, Giorgia Silani","doi":"10.1016/j.biopsych.2025.02.007","DOIUrl":"https://doi.org/10.1016/j.biopsych.2025.02.007","url":null,"abstract":"<p><strong>Background: </strong>COVID-19 lockdowns were linked to a surge in unhealthy food-related behaviors, potentially as an attempt to cope with disrupted social homeostasis. Here, we tested bidirectional associations between momentary psychological states and prospective food consumption, and the moderation by quality and quantity of social interactions.</p><p><strong>Methods: </strong>We conducted a preregistered ecological momentary assessment (EMA) study in Austria, Italy and Germany during the first COVID-19 lockdown. Multiple times a day for seven consecutive days, 798 participants (557 women, M<sub>age</sub> = 31.88) reported on momentary stress, mood, and wanting of food rich in sugar, fat and salt, consumption and enjoyment since the last prompt, and quantity and quality of social interactions since the last prompt.</p><p><strong>Results: </strong>Momentary stress was positively linked to food wanting, but not prospective food consumption. Mood valence and energetic arousal positively predicted prospective food consumption and enjoyment. The effect of mood valence was especially prominent when participants reported having more social interactions. Food consumption was linked to a prospective reduction in stress and an increase in calmness, suggesting it has regulatory functions for affective states. Exploratory findings show that some of these effects generalize to other reward types.</p><p><strong>Conclusions: </strong>During the lockdown, food may have been used to maintain an already positive affective state rather than upregulating an aversive state. Social facilitation of eating may have been especially prominent due to the prioritization of our social needs at the start of an extraordinarily challenging period, possibly orchestrated by the postulated social homeostasis system.</p>","PeriodicalId":8918,"journal":{"name":"Biological Psychiatry","volume":" ","pages":""},"PeriodicalIF":9.6,"publicationDate":"2025-02-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143432288","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Mapping structural neuroimaging trajectories in bipolar disorder: neurobiological and clinical implications.","authors":"Nadine Parker, Christopher R K Ching","doi":"10.1016/j.biopsych.2025.02.009","DOIUrl":"https://doi.org/10.1016/j.biopsych.2025.02.009","url":null,"abstract":"<p><p>Neuroimaging is a powerful non-invasive method for studying brain alterations in bipolar disorder (BD). To date, most neuroimaging studies of BD include smaller cross-sectional samples reporting case versus control comparisons, revealing small to moderate effect sizes. In this narrative review, we discuss the current state of MRI-based, structural imaging studies, which inform our understanding of altered brain trajectories in BD across the lifespan. Alternative methodologies such as those that model patient deviations from age-specific norms are discussed, which may help derive new markers of BD pathophysiology. We discuss evidence from neuroimaging genetics and transcriptomics studies, which attempt to bridge the gap between macro-scale brain variations and underlying micro-scale neurodevelopmental mechanisms. We conclude with a look toward the future and how ambitious investments in longitudinal, deeply phenotyped, population-based cohorts can improve modeling of complex clinical factors and provide more clinically-actionable brain markers for BD.</p>","PeriodicalId":8918,"journal":{"name":"Biological Psychiatry","volume":" ","pages":""},"PeriodicalIF":9.6,"publicationDate":"2025-02-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143432294","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}