Bioinorganic Chemistry and Applications最新文献_第9页

Synthesis, Characterization, Antimicrobial Properties, and Antioxidant Activities of Silver-N-Heterocyclic Carbene Complexes. 银- n杂环卡宾配合物的合成、表征、抗菌性能和抗氧化活性。

IF 3.8 3区化学

Bioinorganic Chemistry and Applications Pub Date : 2023-01-01 DOI: 10.1155/2023/3066299

Donia Bensalah, Nevin Gurbuz, Ismail Özdemir, Rafik Gatri, Lamjed Mansour, Naceur Hamdi

{"title":"Synthesis, Characterization, Antimicrobial Properties, and Antioxidant Activities of Silver-N-Heterocyclic Carbene Complexes.","authors":"Donia Bensalah, Nevin Gurbuz, Ismail Özdemir, Rafik Gatri, Lamjed Mansour, Naceur Hamdi","doi":"10.1155/2023/3066299","DOIUrl":"https://doi.org/10.1155/2023/3066299","url":null,"abstract":"The emergence of antimicrobial resistance has become a major handicap in the fight against bacterial infections, prompting researchers to develop new, more effective, and multimodal alternatives. Silver and its complexes have long been used as antimicrobial agents in medicine because of their lack of resistance to silver, their low potency at low concentrations, and their low toxicity compared to most commonly used antibiotics. N-Heterocyclic carbenes (NHCs) are widely used for coordination of transition metals, mainly in catalytic chemistry. In this study, several N-alkylated benzimidazolium salts 2a-j were synthesized. Then, the N-heterocyclic carbene (NHC) precursor was treated with Ag2O to give silver (I) NHC complexes (3a-j) at room temperature in dichloromethane for 48 h. Ten new silver-NHC complexes were fully characterized by nuclear magnetic resonance (NMR), Fourier transform infrared spectroscopy (FT-IR), elemental analysis, and LC-MSMS (for complexes) techniques. The antibacterial and antioxidant activities of salt 2 and its silver complex 3 were evaluated. All of these complexes were more effective against bacterial strains than comparable ligands. With MIC values ranging from 6.25 to 100 g/ml, the Ag-NHC complex effectively showed strong antibacterial activity. Antioxidant activity was also tested using conventional techniques, such as 2, 2-diphenyl-1-picrylhydrazine (DPPH) and hydrogen peroxide scavenging assays. In DPPH and ABTS experiments, compounds 3a, 3b, 3c, 3e, 3g, and 3i showed significant clearance.","PeriodicalId":8914,"journal":{"name":"Bioinorganic Chemistry and Applications","volume":"2023 ","pages":"3066299"},"PeriodicalIF":3.8,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10238139/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9578373","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Retracted: Study on Nano Drug Particles in the Diagnosis and Treatment of Alzheimer's Disease in the Elderly. 撤下:纳米药物颗粒在老年阿尔茨海默病诊治中的应用研究。

IF 3.8 3区化学

Bioinorganic Chemistry and Applications Pub Date : 2023-01-01 DOI: 10.1155/2023/9816202

Bioinorganic Chemistry And Applications

引用次数: 0

Optimization of Precious Metals Recovery from Electronic Waste by Chromobacterium violaceum Using Response Surface Methodology (RSM). 响应面法优化紫色色杆菌从电子废弃物中回收贵金属的工艺。

IF 3.8 3区化学

Bioinorganic Chemistry and Applications Pub Date : 2023-01-01 DOI: 10.1155/2023/4011670

Wan Nur Fazlina Abdol Jani, Fatihah Suja', Sharifah Iziuna Sayed Jamaludin, Nor Fadilah Mohamad, Noor Hidayu Abdul Rani

{"title":"Optimization of Precious Metals Recovery from Electronic Waste by Chromobacterium violaceum Using Response Surface Methodology (RSM).","authors":"Wan Nur Fazlina Abdol Jani, Fatihah Suja', Sharifah Iziuna Sayed Jamaludin, Nor Fadilah Mohamad, Noor Hidayu Abdul Rani","doi":"10.1155/2023/4011670","DOIUrl":"https://doi.org/10.1155/2023/4011670","url":null,"abstract":"An effective recovery technology will be valuable in the future because the concentration of the precious metal contained in the source can be a key driver in recycling technology. This study aims to use response surface methodology (RSM) through Minitab software to discover the optimum oxygen level (mgL-1), e-waste pulp density (% w/v), and glycine concentration (mgL-1) for the maximum recovery of gold (Au) and silver (Ag). The method of precious metals recovery used for this study was taken from the bioleaching using 2 L of batch stirred tank reactor (BSTR). A Box-Behnken of RSM experimental statistical designs was used to optimize the experimental procedure. The result of the RSM optimization showed that the highest recovery was achieved at an oxygen concentration of 0.56 mgL-1, a pulp density of 1.95%, and a glycine concentration of 2.49 mgL-1, which resulted in the recovery of 62.40% of Au. The pulp density and glycine concentration greatly impact how much Au is bioleached by C. violaceum. As a result, not all of the variables analyzed seem crucial for getting the best precious metals recovery, and some adjustments may be useful in the future.","PeriodicalId":8914,"journal":{"name":"Bioinorganic Chemistry and Applications","volume":"2023 ","pages":"4011670"},"PeriodicalIF":3.8,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10079379/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9265730","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

Retracted: Development Mode of Recreation Belt around the City: Ecological Authenticity or Fashion Creativity? 摘要:环城游憩带的发展模式:生态本真还是时尚创意?

IF 3.8 3区化学

Bioinorganic Chemistry and Applications Pub Date : 2023-01-01 DOI: 10.1155/2023/9862820

Bioinorganic Chemistry And Applications

引用次数: 0

Enhanced Peroxidase-Like and Antibacterial Activity of Ir-CoatedPd-Pt Nanodendrites as Nanozyme. ir包覆pd - pt纳米枝作为纳米酶增强过氧化物酶样和抗菌活性。

IF 3.8 3区化学

Bioinorganic Chemistry and Applications Pub Date : 2023-01-01 DOI: 10.1155/2023/1689455

Jingfang Song, Jian He, Lin Yang, Weiguo Wang, Qinqin Bai, Wei Feng, Ranhui Li

引用次数: 2

Targeting Tumor Microenvironment by Metal Peroxide Nanoparticles in Cancer Therapy. 在癌症治疗中利用过氧化金属纳米粒子靶向肿瘤微环境

IF 4.7 3区化学

Bioinorganic Chemistry and Applications Pub Date : 2022-12-16 eCollection Date: 2022-01-01 DOI: 10.1155/2022/5041399

Simon Ngigi Mbugua

{"title":"Targeting Tumor Microenvironment by Metal Peroxide Nanoparticles in Cancer Therapy.","authors":"Simon Ngigi Mbugua","doi":"10.1155/2022/5041399","DOIUrl":"10.1155/2022/5041399","url":null,"abstract":"Solid tumors have a unique tumor microenvironment (TME), which includes hypoxia, low acidity, and high hydrogen peroxide and glutathione (GSH) levels, among others. These unique factors, which offer favourable microenvironments and nourishment for tumor development and spread, also serve as a gateway for specific and successful cancer therapies. A good example is metal peroxide structures which have been synthesized and utilized to enhance oxygen supply and they have shown great promise in the alleviation of hypoxia. In a hypoxic environment, certain oxygen-dependent treatments such as photodynamic therapy and radiotherapy fail to respond and therefore modulating the hypoxic tumor microenvironment has been found to enhance the antitumor impact of certain drugs. Under acidic environments, the hydrogen peroxide produced by the reaction of metal peroxides with water not only induces oxidative stress but also produces additional oxygen. This is achieved since hydrogen peroxide acts as a reactive substrate for molecules such as catalyse enzymes, alleviating tumor hypoxia observed in the tumor microenvironment. Metal ions released in the process can also offer distinct bioactivity in their own right. Metal peroxides used in anticancer therapy are a rapidly evolving field, and there is good evidence that they are a good option for regulating the tumor microenvironment in cancer therapy. In this regard, the synthesis and mechanisms behind the successful application of metal peroxides to specifically target the tumor microenvironment are highlighted in this review. Various characteristics of TME such as angiogenesis, inflammation, hypoxia, acidity levels, and metal ion homeostasis are addressed in this regard, together with certain forms of synergistic combination treatments.","PeriodicalId":8914,"journal":{"name":"Bioinorganic Chemistry and Applications","volume":"2022 ","pages":"5041399"},"PeriodicalIF":4.7,"publicationDate":"2022-12-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9788889/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10438084","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Development of Novel Bio-mulberry-Reinforced Polyacrylonitrile (PAN) Fibre Organic Brake Friction Composite Materials. 开发新型生物桑葚增强聚丙烯腈（PAN）纤维有机制动摩擦复合材料。

IF 4.7 3区化学

Bioinorganic Chemistry and Applications Pub Date : 2022-07-11 eCollection Date: 2022-01-01 DOI: 10.1155/2022/6426763

Naresh Kumar, L Natrayan, G Kasirajan, S Kaliappan, M D Raj Kamal, Pravin P Patil, Muse Degefe Chewaka

{"title":"Development of Novel Bio-mulberry-Reinforced Polyacrylonitrile (PAN) Fibre Organic Brake Friction Composite Materials.","authors":"Naresh Kumar, L Natrayan, G Kasirajan, S Kaliappan, M D Raj Kamal, Pravin P Patil, Muse Degefe Chewaka","doi":"10.1155/2022/6426763","DOIUrl":"10.1155/2022/6426763","url":null,"abstract":"Natural fibre reinforcement is used in important sectors such as medical, aerospace, automobile, and many other fields. Many articles have reported that natural fibre has the potential to replace synthetic fibres. Natural fibre reinforcement has given good results as a brake friction material. It has already been proven that asbestos causes lung cancer and mesothelioma in brakes. Many people died from the effects of asbestos. According to the World Health Organization's trending brake report, this material leads to serious health issues. This work is going on for the replacement of these materials. Mulberry fibre is a unique material, and PAN fibre is combined with mulberry fibre and used as a brake reinforcement material to replace Kevlar fibre. The brake pads were fabricated with the various wt% of mulberry fibres and PAN fibre [3-12%] with an equal ratio and aramid fibre [3-6%] in the hydraulic hind brake moulding machine. The mechanical, chemical, physical, tribological, and thermal properties were evaluated. MF-2 [6 wt%] mulberry-PAN-fibre-based brake pad composites have shown better results for ultimate shear strength and proof stress, tensile strength, compressive strength, and impact energy.","PeriodicalId":8914,"journal":{"name":"Bioinorganic Chemistry and Applications","volume":"2022 ","pages":"6426763"},"PeriodicalIF":4.7,"publicationDate":"2022-07-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9293573/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10514133","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Estimation of Copper and Cadmium Bioavailability in Contaminated Soil Remediated by Different Plants and Micron Hydroxyapatite 不同植物和微米羟基磷灰石修复污染土壤中铜和镉的生物有效性

IF 3.8 3区化学

Bioinorganic Chemistry and Applications Pub Date : 2022-06-06 DOI: 10.1155/2022/3565550

Lei Xu, Xiangyu Xing, Jianbiao Peng, M. Ji

{"title":"Estimation of Copper and Cadmium Bioavailability in Contaminated Soil Remediated by Different Plants and Micron Hydroxyapatite","authors":"Lei Xu, Xiangyu Xing, Jianbiao Peng, M. Ji","doi":"10.1155/2022/3565550","DOIUrl":"https://doi.org/10.1155/2022/3565550","url":null,"abstract":"A three-year in situ remediation experiment was carried out to understand the effect of combined phytoremediation with chemical materials on the bioavailability of heavy metals in soil. Indigenous weed (Setaria pumila), energy plant (Pennisetum sp.), cadmium (Cd)-hyperaccumulator (Sedum plumbizincicola), and copper (Cu)-tolerant plant (Elsholtzia splendens) were used as the phytoremediation plants aided by micron hydroxyapatite (1% wt). The bioavailability of Cu and Cd in soil was evaluated during the three years. The results showed that the four plants combined with micron hydroxyapatite significantly increased soil pH and soil organic carbon (SOC), and decreased Cu and Cd fractions extracted by CaCl2 and diffusive gradients in thin films (DGT) than the untreated soils, respectively. Because of the large biomass, the accumulation of Cu and Cd is the largest in Pennisetum sp. followed by Elsholtzia splendens, Sedum plumbizincicola, and Setaria pumila. The bioavailability of Cu and Cd is significantly negatively correlated with pH, soil organic carbon, available phosphorus, and available potassium. Moreover, the correlation is mainly related to the addition of micron hydroxyapatite. The accumulation of Cu and Cd is the combined action of the soil bioavailability of Cu, Cd, and biomass. Our results suggest that Pennisetum sp. can act as an appropriate remediation plant for phytoremediation aided by amendments.","PeriodicalId":8914,"journal":{"name":"Bioinorganic Chemistry and Applications","volume":"636 1","pages":""},"PeriodicalIF":3.8,"publicationDate":"2022-06-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"83430338","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Multifunctional Core-Shell NiFe2O4 Shield with TiO2/rGO Nanostructures for Biomedical and Environmental Applications 具有TiO2/rGO纳米结构的多功能核壳NiFe2O4屏蔽在生物医学和环境中的应用

IF 3.8 3区化学

Bioinorganic Chemistry and Applications Pub Date : 2022-05-30 DOI: 10.1155/2022/4805490

R. Esther Nimshi, J. Judith Vijaya, B. Al-Najar, L. Hazeem, M. Bououdina, L. John Kennedy, K. Kombaiah, S. Bellucci

{"title":"Multifunctional Core-Shell NiFe2O4 Shield with TiO2/rGO Nanostructures for Biomedical and Environmental Applications","authors":"R. Esther Nimshi, J. Judith Vijaya, B. Al-Najar, L. Hazeem, M. Bououdina, L. John Kennedy, K. Kombaiah, S. Bellucci","doi":"10.1155/2022/4805490","DOIUrl":"https://doi.org/10.1155/2022/4805490","url":null,"abstract":"Multifunctional core@shell nanoparticles have been synthesized in this paper through 3 stages: NiFe2O4 nanoparticles by microwave irradiation using Pedalium murex leaf extract as a fuel, core@shell NiFe2O4@TiO2 nanoparticles by sol-gel, and NiFe2O4@TiO2@rGO by sol-gel using preprepared reduced graphene oxide obtained by modified Hummer's method. XRD analysis confirmed the presence of both cubic NiFe2O4 spinel and tetragonal TiO2 rutile phases, while Raman spectroscopy analysis displays both D and G bands (ID/IG = 1.04) associated with rGO. Morphological observations by HRTEM reveal a core-shell nanostructure formed by NiFe2O4 core as confirmed by SAED with subsequent thin layers of TiO2 and rGO. Magnetic measurements show a ferromagnetic behavior, where the saturation magnetization drops drastically from 45 emu/g for NiFe2O4 to 15 emu/g after TiO2 and rGO nonmagnetic bilayers coating. The as-fabricated multifunctional core@shell nanostructures demonstrate tunable self-heating characteristics: rise of temperature and specific absorption rate in the range of ΔT = 3–10°C and SAR = 3–58 W/g, respectively. This effectiveness is much close to the threshold temperature of hyperthermia (45°C), and the zones of inhibition show the better effective antibacterial activity of NTG against various Gram-positive and Gram-negative bacterial strains besides simultaneous good efficient, stable, and removable sonophotocatalyst toward the TC degradation.","PeriodicalId":8914,"journal":{"name":"Bioinorganic Chemistry and Applications","volume":"43 1","pages":""},"PeriodicalIF":3.8,"publicationDate":"2022-05-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"82531213","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 7

Inhibition of Staphylococcus aureus α-Hemolysin Production Using Nanocurcumin Capped Au@ZnO Nanocomposite 纳米姜黄素覆盖Au@ZnO纳米复合材料对金黄色葡萄球菌α-溶血素产生的抑制作用

IF 3.8 3区化学

Bioinorganic Chemistry and Applications Pub Date : 2022-05-28 DOI: 10.1155/2022/2663812

M. Jabir, Taha M. Rashid, Uday M. Nayef, S. Albukhaty, F. Almalki, Jawaher J Albaqami, A. Alyamani, Z. Taqi, G. Sulaiman

{"title":"Inhibition of Staphylococcus aureus α-Hemolysin Production Using Nanocurcumin Capped Au@ZnO Nanocomposite","authors":"M. Jabir, Taha M. Rashid, Uday M. Nayef, S. Albukhaty, F. Almalki, Jawaher J Albaqami, A. Alyamani, Z. Taqi, G. Sulaiman","doi":"10.1155/2022/2663812","DOIUrl":"https://doi.org/10.1155/2022/2663812","url":null,"abstract":"Nanoparticles of gold with zinc oxide (Au@ZnO NPs) were prepared by laser ablation and then capped with curcumin nanoparticles (Cur-Au@ZnO NPs). The synthesized NPs were characterized using different techniques, including transmission electron microscopy (TEM), Fourier-transform infrared spectroscopy (FTIR), UV-visible spectroscopy, and X-ray diffraction. In addition, the ability of NPs as a promising antibacterial agent was tested against Staphylococcus aureus through the agar well diffusion method and AO/EtBr staining assay. The results showed that the prepared nanoparticles (Cur-Au@ZnO) served as an antibacterial agent and can destroy the bacterial cells by losing the cell wall integrity and penetrating the cytoplasmic membrane. Moreover, the findings confirmed the role of the formed NPs in attenuation of the adherence and invasion of S. aureus to rat embryonic fibroblast (REF) cells. Furthermore, the activity of Cur-Au@ZnO NPs against the S. aureus α-hemolysin toxin was evaluated using the western blot technique, using human alveolar epithelial cells (A549), and through histopathology examination in a mouse model. In conclusion, the built Cur-Au@ZnO NPs can be used as a potential antibacterial agent and an inhibitor of α-hemolysin toxin secreted by S. aureus. These NPs may offer a new strategy in combating pathogen infections and in the future for biomedical and pharmaceutical applications.","PeriodicalId":8914,"journal":{"name":"Bioinorganic Chemistry and Applications","volume":"2 1","pages":""},"PeriodicalIF":3.8,"publicationDate":"2022-05-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"89693619","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 27