Bioinorganic Chemistry and Applications最新文献

{"title":"Optimization of Precious Metals Recovery from Electronic Waste by <i>Chromobacterium violaceum</i> Using Response Surface Methodology (RSM).","authors":"Wan Nur Fazlina Abdol Jani,&nbsp;Fatihah Suja',&nbsp;Sharifah Iziuna Sayed Jamaludin,&nbsp;Nor Fadilah Mohamad,&nbsp;Noor Hidayu Abdul Rani","doi":"10.1155/2023/4011670","DOIUrl":"https://doi.org/10.1155/2023/4011670","url":null,"abstract":"<p><p>An effective recovery technology will be valuable in the future because the concentration of the precious metal contained in the source can be a key driver in recycling technology. This study aims to use response surface methodology (RSM) through Minitab software to discover the optimum oxygen level (mgL^-1), e-waste pulp density (% w/v), and glycine concentration (mgL^-1) for the maximum recovery of gold (Au) and silver (Ag). The method of precious metals recovery used for this study was taken from the bioleaching using 2 L of batch stirred tank reactor (BSTR). A Box-Behnken of RSM experimental statistical designs was used to optimize the experimental procedure. The result of the RSM optimization showed that the highest recovery was achieved at an oxygen concentration of 0.56 mgL^-1, a pulp density of 1.95%, and a glycine concentration of 2.49 mgL^-1, which resulted in the recovery of 62.40% of Au. The pulp density and glycine concentration greatly impact how much Au is bioleached by <i>C. violaceum</i>. As a result, not all of the variables analyzed seem crucial for getting the best precious metals recovery, and some adjustments may be useful in the future.</p>","PeriodicalId":8914,"journal":{"name":"Bioinorganic Chemistry and Applications","volume":null,"pages":null},"PeriodicalIF":3.8,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10079379/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9265730","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Retracted: Development Mode of Recreation Belt around the City: Ecological Authenticity or Fashion Creativity?","authors":"Bioinorganic Chemistry And Applications","doi":"10.1155/2023/9862820","DOIUrl":"https://doi.org/10.1155/2023/9862820","url":null,"abstract":"<p><p>[This retracts the article DOI: 10.1155/2022/9292668.].</p>","PeriodicalId":8914,"journal":{"name":"Bioinorganic Chemistry and Applications","volume":null,"pages":null},"PeriodicalIF":3.8,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10469363/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10525630","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Enhanced Peroxidase-Like and Antibacterial Activity of Ir-CoatedPd-Pt Nanodendrites as Nanozyme.","authors":"Jingfang Song,&nbsp;Jian He,&nbsp;Lin Yang,&nbsp;Weiguo Wang,&nbsp;Qinqin Bai,&nbsp;Wei Feng,&nbsp;Ranhui Li","doi":"10.1155/2023/1689455","DOIUrl":"https://doi.org/10.1155/2023/1689455","url":null,"abstract":"<p><p>To inhibit the growth of bacteria, the DA-PPI nanozyme with enhanced peroxidase-like activity was synthesized. The DA-PPI nanozyme was obtained by depositing high-affinity element iridium (Ir) on the surface of Pd-Pt dendritic structures. The morphology and composition of DA-PPI nanozyme were characterized using SEM, TEM, and XPS. The kinetic results showed that the DA-PPI nanozyme possessed a higher peroxidase-like activity than that of Pd-Pt dendritic structures. The PL, ESR, and DFT were employed to explain the high peroxidase activity. As a proof of concept, the DA-PPI nanozyme could effectively inhibit <i>E. coli</i> (G^-) and <i>S. aureus</i> (G⁺) due to its high peroxidase-like activity. The study provides a new idea for the design of high active nanozymes and their application in the field of antibacterial.</p>","PeriodicalId":8914,"journal":{"name":"Bioinorganic Chemistry and Applications","volume":null,"pages":null},"PeriodicalIF":3.8,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9946763/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10793939","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Targeting Tumor Microenvironment by Metal Peroxide Nanoparticles in Cancer Therapy.","authors":"Simon Ngigi Mbugua","doi":"10.1155/2022/5041399","DOIUrl":"10.1155/2022/5041399","url":null,"abstract":"<p><p>Solid tumors have a unique tumor microenvironment (TME), which includes hypoxia, low acidity, and high hydrogen peroxide and glutathione (GSH) levels, among others. These unique factors, which offer favourable microenvironments and nourishment for tumor development and spread, also serve as a gateway for specific and successful cancer therapies. A good example is metal peroxide structures which have been synthesized and utilized to enhance oxygen supply and they have shown great promise in the alleviation of hypoxia. In a hypoxic environment, certain oxygen-dependent treatments such as photodynamic therapy and radiotherapy fail to respond and therefore modulating the hypoxic tumor microenvironment has been found to enhance the antitumor impact of certain drugs. Under acidic environments, the hydrogen peroxide produced by the reaction of metal peroxides with water not only induces oxidative stress but also produces additional oxygen. This is achieved since hydrogen peroxide acts as a reactive substrate for molecules such as catalyse enzymes, alleviating tumor hypoxia observed in the tumor microenvironment. Metal ions released in the process can also offer distinct bioactivity in their own right. Metal peroxides used in anticancer therapy are a rapidly evolving field, and there is good evidence that they are a good option for regulating the tumor microenvironment in cancer therapy. In this regard, the synthesis and mechanisms behind the successful application of metal peroxides to specifically target the tumor microenvironment are highlighted in this review. Various characteristics of TME such as angiogenesis, inflammation, hypoxia, acidity levels, and metal ion homeostasis are addressed in this regard, together with certain forms of synergistic combination treatments.</p>","PeriodicalId":8914,"journal":{"name":"Bioinorganic Chemistry and Applications","volume":null,"pages":null},"PeriodicalIF":4.7,"publicationDate":"2022-12-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9788889/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10438084","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Deferiprone-Resveratrol Hybrid, an Iron-Chelating Compound, Acts as an Antimalarial and Hepatoprotective Agent in <i>Plasmodium berghei</i>-Infected Mice.","authors":"Hataichanok Chuljerm, Supawadee Maneekesorn, Chuchard Punsawad, Voravuth Somsak, Yongmin Ma, Jetsada Ruangsuriya, Somdet Srichairatanakool, Pimpisid Koonyosying","doi":"10.1155/2022/3869337","DOIUrl":"10.1155/2022/3869337","url":null,"abstract":"<p><p>Free heme in plasma acts as a prooxidant; thus, it is bound to hemopexin and eliminated by the liver. High iron content in the liver can support <i>Plasmodium</i> growth and cause oxidative liver injury. Inversely, the withholding of excessive iron can inhibit this growth and protect the liver against malaria infection. This study examined the effects of a deferiprone-resveratrol (DFP-RVT) hybrid on malaria parasites and its relevant hepatoprotective properties. Mice were infected with <i>P. berghei</i>, gavage DFP-RVT, deferiprone (DFP), and pyrimethamine (PYR) for 8 consecutive days. Blood and liver parameters were then evaluated. The presence of blood-stage parasites was determined using the microscopic Giemsa staining method. Subsequently, plasma liver enzymes, heme, and concentrations of thiobarbituric acid-reactive substances (TBARS) were determined. The liver tissue was examined pathologically and heme and TBARS concentrations were then quantified. The results indicate that the suppression potency against <i>P. berghei</i> growth occurred as follows: PYR > DFP-RVT hybrid > DFP. Importantly, DFP-RVT significantly improved RBC size, restored alanine aminotransferase and alkaline activities, and increased heme and TBARS concentrations. The compound also reduced the liver weight index, heme, and TBARS concentrations significantly when compared to mice that were untreated. Our findings support the contention that the hepatoprotective effect of DFP-RVT is associated with parasite burden, iron depletion, and lipid peroxidation in the host.</p>","PeriodicalId":8914,"journal":{"name":"Bioinorganic Chemistry and Applications","volume":null,"pages":null},"PeriodicalIF":4.7,"publicationDate":"2022-11-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9715320/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"35255298","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Evaluation of Behavior of 13X Zeolite Modified with Transition Metals for Catalytic Applications.","authors":"Elena David","doi":"10.1155/2022/7352074","DOIUrl":"https://doi.org/10.1155/2022/7352074","url":null,"abstract":"<p><p>This work was intended to develop catalysts based on 13X zeolite modified with transition metals for catalytic applications. In this regard, 13X zeolite was modified by loading of transition metals such as Fe, Co, Cu and various types of catalysts such as Fe-, Co-, Cu-, Fe-Co-, Fe-Cu-, and Co-Cu/13X zeolite were obtained. To prepare these catalysts, the wet impregnation method and metallic precursors were used. The catalysts were characterized by SEM, XRD, BET, and ammonia adsorption. Then the catalytic performance was investigated during upgrading of rapeseed residual biomass pyrolysis vapors using this catalysts and a fixed-bed reactor in two stages. Experimental results showed that the addition of transition metals improved the catalytic selectivity towards aromatic hydrocarbons and Fe-Cu/13X zeolite catalyst was the best and had a high deoxygenation activity (from 62.45% to 20.56%), produced maximum monoaromatic hydrocarbons (of 27.45%), the oxygen content in bio-oil was reduced from 34.98 wt% to 16.06 wt%, the calorific value increased and thus the bio-oil quality was improved.</p>","PeriodicalId":8914,"journal":{"name":"Bioinorganic Chemistry and Applications","volume":null,"pages":null},"PeriodicalIF":3.8,"publicationDate":"2022-10-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9629948/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40471229","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Molecular Docking and Green Synthesis of Bioinorganic TiO₂ Nanoparticles against <i>E.coli</i> and <i>S.aureus</i>.","authors":"Rasha Hamed Al-Serwi, Mohamed El-Sherbiny, T V Ajay Kumar, Abdulmalik Abdulghani Qasim, Thekra Khattar, Yahia Alghazwani, Ali Alqahtani, Venkatesan Krishnaraju, Jamal Moideen Muthu Mohamed, Venkatesa Prabhu Sundramurthy","doi":"10.1155/2022/1142727","DOIUrl":"10.1155/2022/1142727","url":null,"abstract":"<p><p>This study used a simple solution evaporation approach to make a bioinorganic titanium dioxide (Bi-TiO₂) photocatalyst for dye contaminant degradation. A variety of techniques, including <i>X</i>-ray diffraction (XRD), Fourier-transform infrared (FT-IR) spectroscopy, scanning electron microscopy (SEM) coupled with energy dispersive <i>X</i>-ray analysis (EDAX), and differential reflectance spectroscopy, had been employed to classify the structural and optical properties of the prepared bioinorganic photocatalyst (UV-DRS). Using simulated solar irradiation, the photocatalytic activity of the produced Bi-TiO₂ nanoparticles was examined by detecting the degradation of a solution of methylene blue (MB) as a model dye molecule. The developed Bi-TiO₂ photocatalyst demonstrates superior photocatalytic action than commercially available powder TiO₂, according to photo-degradation experiments. E.<i>coli</i> and S.<i>aureus</i> bacterial strains were employed to assess the antibacterial activity of Bi-TiO₂ nanoparticles. The most active molecules that gain antibacterial activity were examined in isolated or extracted components from the tulsi plant. The chosen compounds were docked with thymidylate kinase (TMPK), a potential therapeutic goal for the preparation of novel antibacterial drugs with the PDB ID of 4QGG. Five compounds, namely rosmarinic acid, vicenin-2, orientin, vitexin, and isoorientin, out of the 27 chosen compounds, showed a higher docking score and may aid in boosting antibacterial activity. The synthesized Bi-TiO₂ nanoparticles produced antibacterial activity that was effective against Gram-positive bacteria. The nanomaterials that have been synthesized have a lot of potential in wastewater treatment and biomedical management technologies.</p>","PeriodicalId":8914,"journal":{"name":"Bioinorganic Chemistry and Applications","volume":null,"pages":null},"PeriodicalIF":3.8,"publicationDate":"2022-10-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9588338/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"77135489","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Facile Fabrication of CuO Nanoparticles Embedded in N-Doped Carbon Nanostructure for Electrochemical Sensing of Dopamine.","authors":"Nebras Sobahi,&nbsp;Mohd Imran,&nbsp;Mohammad Ehtisham Khan,&nbsp;Akbar Mohammad,&nbsp;Md Mottahir Alam,&nbsp;Taeho Yoon,&nbsp;Ibrahim M Mehedi,&nbsp;Mohammad A Hussain,&nbsp;Mohammed J Abdulaal,&nbsp;Ahmad A Jiman","doi":"10.1155/2022/6482133","DOIUrl":"https://doi.org/10.1155/2022/6482133","url":null,"abstract":"<p><p>In the present study, a highly selective and sensitive electrochemical sensing platform for the detection of dopamine was developed with CuO nanoparticles embedded in N-doped carbon nanostructure (CuO@NDC). The successfully fabricated nanostructures were characterized by standard instrumentation techniques. The fabricated CuO@NDC nanostructures were used for the development of dopamine electrochemical sensor. The reaction mechanism of a dopamine on the electrode surface is a three-electron three-proton process. The proposed sensor's performance was shown to be superior to several recently reported investigations. Under optimized conditions, the linear equation for detecting dopamine by differential pulse voltammetry is <i>I</i> _pa (<i>μ</i>A) = 0.07701 <i>c</i> (<i>μ</i>M) - 0.1232 (<i>R</i> ² = 0.996), and the linear range is 5-75 <i>μ</i>M. The limit of detection (LOD) and sensitivity were calculated as 0.868 <i>μ</i>M and 421.1 <i>μ</i>A/<i>μ</i>M, respectively. The sensor has simple preparation, low cost, high sensitivity, good stability, and good reproducibility.</p>","PeriodicalId":8914,"journal":{"name":"Bioinorganic Chemistry and Applications","volume":null,"pages":null},"PeriodicalIF":3.8,"publicationDate":"2022-10-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9586835/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40653517","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The Adsorption Potential of Cr from Water by ZnO Nanoparticles Synthesized by <i>Azolla pinnata</i>.","authors":"Ou Wenjie,&nbsp;Waqas Ahmed,&nbsp;Fu Xiuxian,&nbsp;Wang Lu,&nbsp;Li Jiannan,&nbsp;Yang Jie,&nbsp;Rana Muhammad Ammar Asghar,&nbsp;Mohsin Mahmood,&nbsp;Juha M Alatalo,&nbsp;Muhammad Imtiaz,&nbsp;Weidong Li,&nbsp;Sajid Mehmood","doi":"10.1155/2022/6209013","DOIUrl":"https://doi.org/10.1155/2022/6209013","url":null,"abstract":"<p><p>Aqueous solutions containing toxic elements (TEs) (such as hexavalent chromium (Cr (VI)) can be toxic to humans even at trace levels. Thus, removing TEs from the aqueous environment is essential for the protection of biodiversity, hydrosphere ecosystems, and humans. For plant fabrication of zinc oxide nanoparticles (PF-ZnONPs), <i>Azolla pinnata</i> plants were used, and X-ray diffraction (XRD), energy dispersive spectroscopy (EDS), SEM, and FTIR techniques were used for the identification of PF-ZnONPs and ZnONPs, which were used to remove Cr (VI) from aqueous solution. A number of adsorption parameters were studied, including pH, dose, concentration of metal ions, and contact time. The removal efficiency of PF-ZnONPs for Cr (VI) has been found to be 96% at a time (60 min), 69.02% at pH 4, and 70.43% at a dose (10 mg·L^-1). It was found that the pseudo-second-order model best described the adsorption of Cr (VI) onto PF-ZnONPs, indicating a fast initial adsorption via diffusion. The experimental data were also highly consistent with the Langmuir isotherm model calculations.</p>","PeriodicalId":8914,"journal":{"name":"Bioinorganic Chemistry and Applications","volume":null,"pages":null},"PeriodicalIF":3.8,"publicationDate":"2022-10-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9578909/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40560896","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Silver Nanoparticles Stabilized by Poly (Vinyl Pyrrolidone) with Potential Anticancer Activity towards Prostate Cancer.","authors":"Ahmed A H Abdellatif, Ahmed Abdelfattah, Abdellatif Bouazzaoui, Shaaban K Osman, Issa Saad Al-Moraya, Abdulaziz M Saleh Showail, Mansour Alsharidah, Ashraf Aboelela, Osamah Al Rugaie, Tarek M Faris, Hesham M Tawfeek","doi":"10.1155/2022/6181448","DOIUrl":"10.1155/2022/6181448","url":null,"abstract":"<p><p>Tumor necrosis factor (TNF-<i>α</i>) and inflammatory cytokine (IL-6) play a vital role in various cellular incidents such as the proliferation and death of cells during carcinogenesis. Hence, regulation of these biomarkers could be a promising tool for controlling tumor progression using nanoformulations. Silver nanoparticles-poly (vinyl pyrrolidone) (AgNPs-PVP) were prepared using the reduction of silver nitrate and stabilized with PVP. They are characterized through yield percentage, UV-VIS, FT-IR, size, charge, and morphology. The obtained AgNPs were tested for anticancer activity against prostate cancer (PC 3) and human skin fibroblast (HFS) cell lines. Moreover, biomarker-based confirmations like TNF-<i>α</i> and IL-6 were estimated. The synthesized AgNPs-PVP were stable, spherical in shape, with particle sizes of 122.33 ± 17.61 nm, a polydispersity index of 0.49 ± 0.07, and a negative surface charge of -19.23 ± 0.61 mV. <i>In vitro</i> cytotoxicity testing showed the AgNPs-PVP exhibited antiproliferation properties in PC3 in a dose-dependent manner. In addition, when compared to control cells, AgNPs-PVP has lower TNF-<i>α</i> with a significant value ( ^<i>∗</i> <i>p</i> < 0.05); the value reached 16.84 ± 0.71 pg/ml versus 20.81 ± 0.44 pg/ml, respectively. In addition, HSF cells showed a high level of reduction ( ^{<i>∗∗∗</i>} <i>p</i> < 0.001) in IL-6 production. This study suggested that AgNPs-PVP could be a possible therapeutic agent for human prostate cancer and anti-IL-6 in cancerous and noncancerous cells. Further studies will be performed to investigate the effect of AgNPs-PVP in different types of cancer.</p>","PeriodicalId":8914,"journal":{"name":"Bioinorganic Chemistry and Applications","volume":null,"pages":null},"PeriodicalIF":3.8,"publicationDate":"2022-09-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9553549/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"33517431","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}