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In My Opinion—Interview with the Expert 在我看来-采访专家
Pediatric asthma, allergy & immunology Pub Date : 2004-07-08 DOI: 10.1089/088318704322994994
N. Sander
{"title":"In My Opinion—Interview with the Expert","authors":"N. Sander","doi":"10.1089/088318704322994994","DOIUrl":"https://doi.org/10.1089/088318704322994994","url":null,"abstract":"Nancy Sander is president and founder of the Allergy & Asthma Network Mothers of Asthmatics (AANMA), a nonprofit membership organization providing educational materials and guidance to people with asthma and allergies. Like millions of other parents whose children were born with severe asthma and allergies, Nancy spent many lonely, frustrating, and frightening years in and out of hospital emergency rooms fighting to help her daughter, Brooke. Determined to ease her daughter's plight, she sought to learn all she could about asthma and allergies. Nancy entered her daughter into a drug research program at Georgetown University with profound results. The components of care, communication, and stateof-the-art therapies and medications provided at Georgetown revolutionized Brooke's life and changed the family dynamics so dramatically that Nancy started sharing the good news with others in the Washington, DC, metro area via a newsletter. Through caring for Brooke, Nancy became an expert on the practical aspects ...","PeriodicalId":88951,"journal":{"name":"Pediatric asthma, allergy & immunology","volume":"38 1","pages":"93-96"},"PeriodicalIF":0.0,"publicationDate":"2004-07-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"78365306","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Allergic Bronchopulmonary Aspergillosis with Normal Serum IgE in a Child with Cystic Fibrosis 过敏性支气管肺曲霉病伴囊性纤维化患儿血清IgE正常
Pediatric asthma, allergy & immunology Pub Date : 2004-07-08 DOI: 10.1089/0883187041269922
Danielle Dorsaneo, D. Borowitz, Jack K. Sharp, R. Moss
{"title":"Allergic Bronchopulmonary Aspergillosis with Normal Serum IgE in a Child with Cystic Fibrosis","authors":"Danielle Dorsaneo, D. Borowitz, Jack K. Sharp, R. Moss","doi":"10.1089/0883187041269922","DOIUrl":"https://doi.org/10.1089/0883187041269922","url":null,"abstract":"Diagnostic criteria for allergic bronchopulmonary aspergillosis (ABPA) in patients with cystic fibrosis have required an absolute increase in total serum immunoglobulin E (IgE) to > 1000 IU/mL (2400 ng/mL). Current guidelines recommend in depth evaluation for those with IgE > 500 IU/mL (1200 ng/mL), or even for those with lower values if there is clinical suspicion for ABPA. We present a case of a patient who met all criteria for ABPA with the exception of elevation of IgE above the diagnostic level. An increase in serum IgE from the baseline level, but not > 1000 IU/mL, and subsequent return to baseline corresponded to a clinical exacerbation and resolution of presumptive ABPA.","PeriodicalId":88951,"journal":{"name":"Pediatric asthma, allergy & immunology","volume":"5 1","pages":"146-150"},"PeriodicalIF":0.0,"publicationDate":"2004-07-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"89455562","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 2
Idiopathic Pulmonary Hemosiderosis 特发性肺含铁血黄素沉着症
Pediatric asthma, allergy & immunology Pub Date : 2004-07-08 DOI: 10.1089/0883187041269904
Dmitriy Vaysman, Wilfredo G. Veloira, A. Schuss, Haesoon Lee
{"title":"Idiopathic Pulmonary Hemosiderosis","authors":"Dmitriy Vaysman, Wilfredo G. Veloira, A. Schuss, Haesoon Lee","doi":"10.1089/0883187041269904","DOIUrl":"https://doi.org/10.1089/0883187041269904","url":null,"abstract":"Idiopathic pulmonary hemosiderosis (IPH) is a rare condition of unknown etiology, characterized by hemoptysis, alveolar pulmonary infiltrates on chest radiograph, and iron deficiency anemia. The estimated incidence of IPH is 0.24 and 1.23 cases per million in selected populations. We report a case of a 3-year-old girl with acute onset of respiratory distress, microcytic hypochromic anemia, and bilateral alveolar infiltrates on chest radiograph. Pulmonary hemorrhage was confirmed on bronchoalveolar lavage (BAL) and lung biopsy. Other causes of pulmonary hemorrhage were excluded. She was treated with prednisolone, and when her anemia relapsed, azathioprine was added to prednisolone with a good response.","PeriodicalId":88951,"journal":{"name":"Pediatric asthma, allergy & immunology","volume":"28 1","pages":"151-155"},"PeriodicalIF":0.0,"publicationDate":"2004-07-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"75341787","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The High Prevalence of Rhinitis, Rhinoconjunctivitis, and Eczema in Costa Rican Schoolchildren Studied with the ISAAC Protocol 哥斯达黎加学童鼻炎、鼻结膜炎和湿疹的高患病率与ISAAC方案研究
Pediatric asthma, allergy & immunology Pub Date : 2004-07-08 DOI: 10.1089/088318704322994967
M. Soto-Quiros, M. Soto-Martínez, L. Hanson
{"title":"The High Prevalence of Rhinitis, Rhinoconjunctivitis, and Eczema in Costa Rican Schoolchildren Studied with the ISAAC Protocol","authors":"M. Soto-Quiros, M. Soto-Martínez, L. Hanson","doi":"10.1089/088318704322994967","DOIUrl":"https://doi.org/10.1089/088318704322994967","url":null,"abstract":"The aim of our study was to estimate the prevalence and severity of allergic rhinitis, rhinoconjunctivitis, and eczema in Costa Rican schoolchildren. We have reported asthma prevalence in the same cohort elsewhere. A questionnaire based survey was conducted on a random sample of children (n = 6144), aged 6-7 years and 13-14 years from 75 educational centers throughout Costa Rica, using the International Study of Asthma and Allergies in Childhood (ISAAC) protocol. The prevalence in the 6- to 7-year-old group of rhinitis ever was 32.7%, rhinitis in the last 12 months 26.6%, and rhinoconjunctivitis 12.1%. In the 13- to 14-yearold group, the presence of rhinitis ever was 39.2%, rhinitis in the last 12 months 30.9% and rhinoconjunctivitis 14.8, showing significantly higher figures for the older group (p = 0.001, p = 0.0001, p = 0.001). The prevalence of \"ever having had a diagnosis of rhinitis\" (by a physician) was 5.9% and 4.8% in the two age groups (NS). Children were more affected during the rainy season, M...","PeriodicalId":88951,"journal":{"name":"Pediatric asthma, allergy & immunology","volume":"22 1","pages":"71-80"},"PeriodicalIF":0.0,"publicationDate":"2004-07-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"74149745","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 2
Effects of Allergen Avoidance at High Altitude on Children with Asthma or Atopic Dermatitis 高原过敏原躲避对儿童哮喘或特应性皮炎的影响
Pediatric asthma, allergy & immunology Pub Date : 2004-07-08 DOI: 10.1089/088318704322994903
F. Petermann, A. Gulyas, K. Niebank, P. Warschburger
{"title":"Effects of Allergen Avoidance at High Altitude on Children with Asthma or Atopic Dermatitis","authors":"F. Petermann, A. Gulyas, K. Niebank, P. Warschburger","doi":"10.1089/088318704322994903","DOIUrl":"https://doi.org/10.1089/088318704322994903","url":null,"abstract":"Patients with atopic diseases benefit from a high-altitude climate, the effectiveness of which may be related to established house dust mite allergy. A relationship between these variables and disease severity as well as inflammatory activity has not been previously studied. The study objectives were: (1) to assess changes in inflammatory levels for children and adolescents with asthma or atopic dermatitis during a 4-week inpatient rehabilitation stay at high altitude, (2) to examine the role of house dust mite sensitization, and (3) to compare the results for the two diagnostic groups. A total of 115 children and adolescents aged 10-16 years were enrolled in the study: 60 suffered from asthma and 55 from atopic dermatitis. The prevalence of house dust mite sensitization was 36.52%. Urine and blood samples were collected on admission to an inpatient rehabilitation clinic and at their discharge 1 month later. Urinary eosinophil protein X (U-EPX) and serum eosinophil cationic protein (S-EPC)-levels were ana...","PeriodicalId":88951,"journal":{"name":"Pediatric asthma, allergy & immunology","volume":"120 1","pages":"15-24"},"PeriodicalIF":0.0,"publicationDate":"2004-07-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"73743192","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 10
Assessing a Community's Pediatric Asthma Care Needs: Insights Gained from Physicians, School Nurses, and Parents 评估社区儿童哮喘护理需求:从医生、学校护士和家长那里获得的见解
Pediatric asthma, allergy & immunology Pub Date : 2004-07-08 DOI: 10.1089/088318704322994912
J. Taylor-Fishwick, D. Major, C. Kelly, F. Butterfoss, S. M. Clarke, Rebekah A. Cardenas
{"title":"Assessing a Community's Pediatric Asthma Care Needs: Insights Gained from Physicians, School Nurses, and Parents","authors":"J. Taylor-Fishwick, D. Major, C. Kelly, F. Butterfoss, S. M. Clarke, Rebekah A. Cardenas","doi":"10.1089/088318704322994912","DOIUrl":"https://doi.org/10.1089/088318704322994912","url":null,"abstract":"Today, about 5 million children in the United States - one in every 15 children under the age of 18 - have asthma. The social and economic costs of childhood asthma are high. Asthma management requires a multifaceted approach, including partnerships among physicians, school nurses, and parents to create a continuum of care that is often missing from conventional health-care delivery systems. At a local level, coalitions are an important strategy for promoting partnerships for the management of asthma. Focus groups were conducted in the Hampton Roads region of southeastern Virginia to provide in-depth information about barriers to the management of asthma. The perspectives of physicians, school nurses, and parents who live in areas characterized as having unusually high rates of emergency department visits or hospitalizations for asthma were included. This paper presents an in-depth analysis of the qualitative data obtained from these focus groups.","PeriodicalId":88951,"journal":{"name":"Pediatric asthma, allergy & immunology","volume":"12 1","pages":"25-35"},"PeriodicalIF":0.0,"publicationDate":"2004-07-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"84973533","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 9
Impact of Age and Administration Regimens on the Suppressive Effect of Inhaled Glucocorticoids on Eosinophil Markers in Children with Asthma 年龄和给药方案对吸入糖皮质激素对哮喘患儿嗜酸性粒细胞抑制作用的影响
Pediatric asthma, allergy & immunology Pub Date : 2004-07-08 DOI: 10.1089/088318704322994930
O. D. Wolthers, C. Heuck
{"title":"Impact of Age and Administration Regimens on the Suppressive Effect of Inhaled Glucocorticoids on Eosinophil Markers in Children with Asthma","authors":"O. D. Wolthers, C. Heuck","doi":"10.1089/088318704322994930","DOIUrl":"https://doi.org/10.1089/088318704322994930","url":null,"abstract":"Inhaled glucocorticoids may suppress the eosinophil markers serum eosinophil cationic protein (ECP) and urine eosinophil protein X (EPX) in children with asthma. The aim of the present study was to see whether age or administration regimen may affect the suppressive effect of inhaled budesonide on serum ECP or serum or urine EPX in children with asthma. Two separate randomized double-blind crossover trials with two treatment periods of 4 weeks duration were conducted. Study 1: Inhaled budesonide 400 μg twice daily versus placebo in 14 13- to 16-year-old adolescents. Study 2: Inhaled budesonide 800 μg once daily versus 400 μg twice daily in 22 prepubertal children aged 5-12 years. Blood and urine samples were collected on the last day of each period for assessment of serum ECP, serum EPX, and urine EPX by radioimmunoassays. In study 1 (the adolescent group), placebo and budesonide serum ECP (mean SEM) were 8.7 (0.9) and 5.5 (0.8) μg/L (p < 0.01), serum EPX 32.2 (2.9) and 24.7 (2.4 μg/L (p = 0.04), and urin...","PeriodicalId":88951,"journal":{"name":"Pediatric asthma, allergy & immunology","volume":"33 1","pages":"45-51"},"PeriodicalIF":0.0,"publicationDate":"2004-07-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"88153832","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 5
Hypersensitivity Pneumonitis in Children 儿童过敏性肺炎
Pediatric asthma, allergy & immunology Pub Date : 2003-12-01 DOI: 10.1089/088318703322751309
A. Knutsen, C. Sotelo‐Avila, G. Albers
{"title":"Hypersensitivity Pneumonitis in Children","authors":"A. Knutsen, C. Sotelo‐Avila, G. Albers","doi":"10.1089/088318703322751309","DOIUrl":"https://doi.org/10.1089/088318703322751309","url":null,"abstract":"Hypersensitivity pneumonitis (extrinsic allergic alveolitis) is an immunologic medicated hypersensitivity reaction to a variety of inhaled allergens that may cause an acute and subacute intersititial pneumonitis and may lead to a chronic end-stage lung disease. Although more common in adults, hypersensitivity pneumonitis needs to be considered in the differential diagnosis of interstitial pneumonitis in children. In children, the most common antigens are from residential exposure to birds, humidifiers, and indoor molds. Serum immunoglobulin G (IgG) antibodies are elevated to the inhaled antigen(s) in hypersensitivity pneumonitis, but they may be present in asymptomatic exposed individuals. The immunopathogenesis involves cellular immunity to inhaled allergens, especially CD+ cytotoxic T cells, multinucleated giant cells, and ultimately granulomas. Pulmonary function studies demonstrate a restrictive pattern with a diffusion defect resulting in hypoxemia. Radiographic changes vary according to the stage of...","PeriodicalId":88951,"journal":{"name":"Pediatric asthma, allergy & immunology","volume":"36 1","pages":"247-264"},"PeriodicalIF":0.0,"publicationDate":"2003-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"84362501","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 3
Case Study of a UFO (Unidentified Foreign Object) UFO(不明飞行物)案例研究
Pediatric asthma, allergy & immunology Pub Date : 2003-12-01 DOI: 10.1089/088318703322751255
Joel M. Brown, R. Padman
{"title":"Case Study of a UFO (Unidentified Foreign Object)","authors":"Joel M. Brown, R. Padman","doi":"10.1089/088318703322751255","DOIUrl":"https://doi.org/10.1089/088318703322751255","url":null,"abstract":"A 9.5-month-old Hispanic female experienced cough and wheeze that persisted beyond a 3-week period. Her primary care physician diagnosed her with asthma. The symptoms did not resolve, and she was referred to a specialist. A chest radiograph revealed asymmetrical aeration with overinflation of the left lung. The patient had no clear history of acute onset of coughing or choking, and the differential diagnosis included intrinsic or extrinsic obstruction to the lumen of the left main-stem bronchus. To assess the cause for the obstruction, a flexible fiberoptic bronchoscopy was planned, with an otolaryngologist and rigid bronchoscope as standby. A foreign body was identified in the distal left main stem bronchus and was retrieved with forceps through the flexible scope without the need for more invasive procedures, such as rigid bronchoscopy or open thoracotomy.","PeriodicalId":88951,"journal":{"name":"Pediatric asthma, allergy & immunology","volume":"20 1","pages":"187-192"},"PeriodicalIF":0.0,"publicationDate":"2003-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"86385869","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 2
Association between Residential Tobacco Smoking Bans, Smoke Exposure, and Pulmonary Function: A Survey of Latino Children with Asthma 住宅禁烟、烟雾暴露和肺功能之间的关系:一项对拉丁裔哮喘儿童的调查
Pediatric asthma, allergy & immunology Pub Date : 2003-12-01 DOI: 10.1089/088318703322751354
A. Martinez-Donate, M. Hovell, D. Wahlgren, S. B. Meltzer, E. Meltzer, C. Hofstetter, G. Matt
{"title":"Association between Residential Tobacco Smoking Bans, Smoke Exposure, and Pulmonary Function: A Survey of Latino Children with Asthma","authors":"A. Martinez-Donate, M. Hovell, D. Wahlgren, S. B. Meltzer, E. Meltzer, C. Hofstetter, G. Matt","doi":"10.1089/088318703322751354","DOIUrl":"https://doi.org/10.1089/088318703322751354","url":null,"abstract":"Exposure to environmental tobacco smoke (ETS) is a risk factor for asthma development and progression. ETS exposure among children takes place mainly in the home. This paper examines the relationship between household smoking restrictions, the level of ETS exposure, and the asthma status of a sample of 192 low-income Latino asthmatic children, living with at least one smoker. Families were recruited throughout San Diego County, California. Mothers were interviewed on use of smoking restriction policies, possible correlates of these policies, their children's ETS exposure, asthma morbidity, and use of medical care. The children's pulmonary function was also assessed. As compared with the lack of smoking restrictions, a total ban on smoking was associated with a significantly lower reported level of children's ETS exposure at home (p < 0.05), in the car (p < 0.05), and overall (p < 0.01). Multivariate analyses indicated that having a smoking ban was associated with less severe asthma symptoms (p < 0.05), le...","PeriodicalId":88951,"journal":{"name":"Pediatric asthma, allergy & immunology","volume":"106 1","pages":"305-317"},"PeriodicalIF":0.0,"publicationDate":"2003-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"79335770","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 9
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