{"title":"Resolution of Debilitating Large Local Reaction from Imported Fire Ant Stings with Rush Immunotherapy: A Case Report","authors":"L. Hagan","doi":"10.1089/088318700750070448","DOIUrl":"https://doi.org/10.1089/088318700750070448","url":null,"abstract":"Although treatment of systemic reactions with both flying Hymenoptera and imported fire ant (IFA) with immunotherapy is the standard of care, immunotherapy is currently not recommended for the perceived relatively minor hazard of large local reactions. However, some large local reactions can be debilitating, resulting in severe swelling, pain and discomfort as well as loss of function of an extremity. The objective of this study was to evaluate whether rush immunotherapy (RIT) with IFA whole-body extract can prevent debilitating large local reactions to the sting of the IFA. An 8-year-old boy with debilitating large local reactions to the sting of IFAs underwent a 2-day RIT protocol with IFA whole-body extract. Sting challenges were performed before, 30, and 90 days after RIT. The area of the wheal and flare were measured at 1-hour post-sting and the area of induration at 24 hours. There was a 96% increase in the 1-hour post-sting wheal at 1 month but a 60% decrease from baseline at 3 months post-RIT. The...","PeriodicalId":88951,"journal":{"name":"Pediatric asthma, allergy & immunology","volume":"38 1","pages":"333-338"},"PeriodicalIF":0.0,"publicationDate":"2000-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"80736201","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Anaphylaxis Complicating Routine Childhood Immunization: Hemophilus Influenza b Conjugated Vaccine","authors":"M. Nelson, H. Oaks, Laurie J. Smith, R. Engler","doi":"10.1089/088318700750070411","DOIUrl":"https://doi.org/10.1089/088318700750070411","url":null,"abstract":"Increasing numbers of vaccines are being introduced into the infant and childhood immunization schedules. Immediate hypersensitivity reactions to include anaphylaxis can occur during the immunization visit. Determining the cause of a vaccine-associated immediate hypersensitivity reaction may require multiple specific skin test and challenge procedures. We report the case of a 4-month-old Caucasian male who developed an urticarial rash within 10 minutes of receiving his 4-month immunizations, diphtheria-tetanus-acellular pertussis (DTaP), inactivated polio (IPV), and the diphtheria mutant protein (CRM197) conjugated Hemophilus influenzae type b (HbOC). The child was referred for an allergy-immunology consultation in order to determine the cause of the reaction and a future vaccine management strategy. Negative prick skin tests were obtained with full-strength vaccine and subsequent dose challenges with DTaP and IPV vaccines were tolerated without reaction. Prick skin testing with full-strength HbOC was neg...","PeriodicalId":88951,"journal":{"name":"Pediatric asthma, allergy & immunology","volume":"98 11 1","pages":"315-321"},"PeriodicalIF":0.0,"publicationDate":"2000-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"83328563","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Allergic Fungal Sinusitis: A Review of the Literature","authors":"D. Carlton, T. Freeman","doi":"10.1089/088318700750070402","DOIUrl":"https://doi.org/10.1089/088318700750070402","url":null,"abstract":"Allergic fungal sinusitis was first described in the 1980s. Interest in this disease entity has steadily grown. Several case series have been published describing more than 100 patients. An overview of both typical and unusual clinical presentations, laboratory findings, and radiographic features is provided in this review. Immunologic evaluation of these patients has found some evidence for an IgE-mediated hypersensitivity in the pathogenesis of this eosinophilic reaction. Despite the wealth of literature, controversy exists as to the optimal management of these patients. This review discusses the published outcomes of surgical and medical management, as well as offering some suggestions for monitoring patients for recurrence. In addition, treatment of allergic fungal sinusitis utilizing immunotherapy with fungal extracts is discussed. (Pediatr Asthma Allergy Immunol 2000;14[4]:307–314.)","PeriodicalId":88951,"journal":{"name":"Pediatric asthma, allergy & immunology","volume":"79 1","pages":"307-314"},"PeriodicalIF":0.0,"publicationDate":"2000-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"88493438","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Sports and Asthma","authors":"D. Provencher, S. Bahna","doi":"10.1089/088318700750070358","DOIUrl":"https://doi.org/10.1089/088318700750070358","url":null,"abstract":"Whereas exercise-induced bronchospasm (EIB) is common among asthmatics, exercise-induced asthma (EIA) may occur in otherwise healthy individuals, particularly athletes. Baseline pulmonary function testing (PFT) should be obtained in all suspected cases. It may be advisable to screen highly competitive athletes who might be at a higher risk for EIA/EIB than average. The mechanism of EIA/EIB may involve airway cooling and rewarming and/or airway drying with mediator release. The mainstay of treatment is short-acting inhaled bronchodilators prior to exercise, in addition to regularly used anti-inflammatory agent, if required. Pre-exercise warm-ups may be helpful, at least in part. The diagnosis should be confirmed with exercise challenge testing for individuals who do not respond to treatment. These individuals may have alternate diagnoses. (Pediatr Asthma Allergy Immunol 2000; 14[4]:269–276.)","PeriodicalId":88951,"journal":{"name":"Pediatric asthma, allergy & immunology","volume":"69 1","pages":"269-276"},"PeriodicalIF":0.0,"publicationDate":"2000-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"83326753","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Anaphylaxis to Benzathine Penicillin G","authors":"Di Napoli, T. Neeno","doi":"10.1089/088318700750070439","DOIUrl":"https://doi.org/10.1089/088318700750070439","url":null,"abstract":"We report on two military trainees who experienced anaphylaxis following an injection of benzathine penicillin G (BPG). A total of 9203 trainees received a prophylactic dose of BPG over a 6-month period for an incidence rate of 0.022%. One of the trainees experienced biphasic or recurrent anaphylaxis. We discuss the issue of management of anaphylaxis following an injection of a depot form of penicillin especially with regards to biphasic anaphylaxis. (Pediatr Asthma Allergy Immunol 2000;14[4]:329–332.)","PeriodicalId":88951,"journal":{"name":"Pediatric asthma, allergy & immunology","volume":"23 1","pages":"329-332"},"PeriodicalIF":0.0,"publicationDate":"2000-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"85092333","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Pediatric Inpatient Consultation of Allergy/Immunology","authors":"J. Quinn","doi":"10.1089/088318700750070385","DOIUrl":"https://doi.org/10.1089/088318700750070385","url":null,"abstract":"There are no studies that examine the referral patterns for allergy/immunology consultation from an inpatient pediatric service. The purpose of this study was to examine the referring diagnosis and/or the requested evaluation on consultations from the inpatient pediatric service to allergy/immunology. We reviewed all inpatient consults submitted to allergy/ immunology from 1995 to 1999. We selected consults submitted by the inpatient pediatrics service on patients 18 years of age and younger for further review. There were 350 total inpatient consultations over the 5-year period of which 165 (47%) were from pediatrics. Our results demonstrated that the 58% (96/165) of pediatric inpatient consults were for the evaluation of asthma, 13% (22/165) for immunodeficiency evaluation, 9.7% (16/165) for the evaluation of antibiotic allergy, and 7.9% (13/165) for evaluation of anaphylaxis. The leading reason for immunodeficiency consultation was to \"rule-out\" DiGeorge's syndrome (6/22). The leading request from antib...","PeriodicalId":88951,"journal":{"name":"Pediatric asthma, allergy & immunology","volume":"32 1","pages":"293-299"},"PeriodicalIF":0.0,"publicationDate":"2000-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"78497826","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"A Look at Indoor Allergen Environmental Control","authors":"W. Boleman","doi":"10.1089/088318700750070394","DOIUrl":"https://doi.org/10.1089/088318700750070394","url":null,"abstract":"Environmental control is important in the management of allergy, particularly indoor environmental control. These measures may be helpful not only in allergic rhinitis, but also asthma. House dust mite allergen is a major indoor allergen and measures to control allergen level include impermeable encasings for the bedding (perhaps the most important measure), washing bedding preferably at high temperature (130°F), decreasing relative humidity in the home, not having carpet, or if so, using an effective vacuum system, and using air filter devices. The use of chemicals called acaricides have been marketed to kill dust mite as well. Animal dander, another clinically important indoor allergen is best managed by removal of the pet from the home. However, using encasings in the bedroom, vacuuming with an effective vacuum system, using an air filter in the home, and possibly washing the cat, are modalities used to decrease animal dander. The majority of patients tend to benefit most from avoidance of allergens (p...","PeriodicalId":88951,"journal":{"name":"Pediatric asthma, allergy & immunology","volume":"51 1","pages":"301-305"},"PeriodicalIF":0.0,"publicationDate":"2000-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"84657461","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Evaluation of Physicians' Knowledge of Asthma Diagnosis and Treatment Guidelines in a Health Maintenance Organization","authors":"J. Ricci, W. Stewart, Jay Gerstenblith, S. Murphy","doi":"10.1089/088318700750070367","DOIUrl":"https://doi.org/10.1089/088318700750070367","url":null,"abstract":"Asthma management is a complex process requiring the active, significant, and consistent attention of physicians and patients. Physician knowledge regarding asthma care was evaluated in this study as part of a comprehensive health improvement strategy to improve the quality of asthma care in health maintenance organizations (HMOs). Sixty-eight randomly selected physicians who treat asthma patients were interviewed on basic clinical knowledge and specific applications of knowledge in four domains: assessment/diagnosis, pharmacological therapy, asthma triggers, and patient management/education (72% participation). The standardized interview, based on 1997 NIH/NHLBI Expert Panel Report 2: Guidelines for the Diagnosis and Management of Asthma, was administered by a pulmonologist. Each domain contributed 25 points to the overall score of 100 points. Physicians were trained in pediatrics (46%), internal medicine (28%), and family practice (22%). Mean overall asthma clinical knowledge score was 46 ± 9. Mean doma...","PeriodicalId":88951,"journal":{"name":"Pediatric asthma, allergy & immunology","volume":"75 1","pages":"277-285"},"PeriodicalIF":0.0,"publicationDate":"2000-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"80864280","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}