Biomatter最新文献_第9页

Embroidered and surface coated polycaprolactone-co-lactide scaffolds: a potential graft for bone tissue engineering. 绣花和表面涂层聚己内酯-共丙交酯支架:骨组织工程的潜在移植物。

Biomatter Pub Date : 2012-07-01 DOI: 10.4161/biom.21931

Barbe Rentsch, Ricardo Bernhardt, Dieter Scharnweber, Wolfgang Schneiders, Stefan Rammelt, Claudia Rentsch

引用次数: 31

Letter from the editor: improving biomaterials through matrix engineering. 编辑来信:通过基质工程改进生物材料。

Biomatter Pub Date : 2012-07-01 DOI: 10.4161/biom.22011

Stefan Rammelt

引用次数: 0

Surface modification of implants in long bone. 长骨种植体的表面修饰。

Biomatter Pub Date : 2012-07-01 DOI: 10.4161/biom.21563

Yvonne Förster, Claudia Rentsch, Wolfgang Schneiders, Ricardo Bernhardt, Jan C Simon, Hartmut Worch, Stefan Rammelt

引用次数: 61

Biomimetic evaluation of β tricalcium phosphate prepared by hot isostatic pressing. 热等静压法制备β磷酸三钙的仿生性能评价。

Biomatter Pub Date : 2012-07-01 DOI: 10.4161/biom.21377

Mihaela Mateescu, Emmanuelle Rguitti, Arnaud Ponche, Michel Descamps, Karine Anselme

{"title":"Biomimetic evaluation of β tricalcium phosphate prepared by hot isostatic pressing.","authors":"Mihaela Mateescu, Emmanuelle Rguitti, Arnaud Ponche, Michel Descamps, Karine Anselme","doi":"10.4161/biom.21377","DOIUrl":"https://doi.org/10.4161/biom.21377","url":null,"abstract":"Two types of completely densified β-TCP tablets were synthesized from a stoichiometric β-TCP powder. The first ones (TCP) were conventionally sintered, while the second ones (TCP-T) were sintered and treated by hot isostatic process (HIP). The HIP produced completely densified materials with relative densities greater than 99.9% and a transparent appearance of tablets. Samples were immersed in culture medium with (CM) or without serum (NCM) in static and dynamic conditions for a biomimetic evaluation. Similarly, SaOs-2 cells were cultured on samples in a static or dynamic flow perfusion system. The results of surface transformation in absence of cells showed that the dynamic condition increased the speed of calcium phosphate precipitations compared with the static condition. The morphology of precipitates was different with nature of tablets. The immersion in CM did impede this precipitation. XPS analysis of TCP-T tablets showed the presence of hydroxyapatite (HA) precipitates after incubation in NCM while octacalcium phosphate (OCP) precipitates were formed after incubation in CM. The analysis of the response of SaOs-2 cells on surfaces showed that the two types of materials are biocompatible. However, the dynamic mode of culture stimulated the differentiation of cells. Finally, it appears that the HIP treatment of TCP produces highly densified and transparent samples that display a good in vitro biocompatibility in static and dynamic culture conditions. Moreover, an interesting result of this work is the relationship between the presence of proteins in the immersion medium and the quality of precipitates formed on hipped TCP surface.","PeriodicalId":8891,"journal":{"name":"Biomatter","volume":"2 3","pages":"103-13"},"PeriodicalIF":0.0,"publicationDate":"2012-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.4161/biom.21377","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"31317304","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 6

Functionalization of biomaterial surfaces using artificial extracellular matrices. 利用人工细胞外基质实现生物材料表面功能化。

Biomatter Pub Date : 2012-07-01 DOI: 10.4161/biom.20921

Susanne Bierbaum, Vera Hintze, Dieter Scharnweber

引用次数: 49

Functional aspects of the interaction between interleukin-8 and sulfated glycosaminoglycans. 白细胞介素-8与硫酸糖胺聚糖相互作用的功能方面。

Biomatter Pub Date : 2012-07-01 DOI: 10.4161/biom.21316

Annelie Pichert, Denise Schlorke, Sandra Franz, Juergen Arnhold

引用次数: 37

New methods to study the composition and structure of the extracellular matrix in natural and bioengineered tissues. 研究天然组织和生物工程组织中细胞外基质组成和结构的新方法。

Biomatter Pub Date : 2012-07-01 DOI: 10.4161/biom.20866

Jürgen Schiller, Daniel Huster

{"title":"New methods to study the composition and structure of the extracellular matrix in natural and bioengineered tissues.","authors":"Jürgen Schiller, Daniel Huster","doi":"10.4161/biom.20866","DOIUrl":"https://doi.org/10.4161/biom.20866","url":null,"abstract":"The extracellular matrix (ECM) comprises a gel of numerous biopolymers that occurs in a multitude of biological tissues. The ECM provides the basic support and mechanical strength of skeletal tissue and is responsible for shape retention. At the same time, the ECM is responsible for the viscoelastic properties and the elasticity of soft tissues. As expected, there are several important diseases that affect and degenerate the ECM with severe consequences for its properties. Bioengineering is a promising approach to support the regenerative capacity of the body. Unfortunately, the biomechanical properties of bioengineered ECM often only poorly meet the standards of their native counterparts. Many bioengineered tissues are characterized by an increased glycosaminoglycan (GAG) but decreased collagen content. This leads to an enhanced water content that strongly alters the viscoelastic and thus the biomechanical properties. Therefore, compositional analysis is important to estimate the tissue quality. We will show that nuclear magnetic resonance (NMR) spectroscopy and soft-ionization mass spectrometry (MS) represent useful techniques for ECM research both in natural and bioengineered tissues. Both methods are strongly complimentary: while MS techniques such as matrix-assisted laser desorption and ionization (MALDI) are excellent and very sensitive analytical tools to determine the collagen and the GAG contents of tissues, NMR spectroscopy provides insight into the molecular architecture of the ECM, its dynamics and other important parameters such as the water content of the tissue as well as the diffusion of molecules within the ECM.","PeriodicalId":8891,"journal":{"name":"Biomatter","volume":"2 3","pages":"115-31"},"PeriodicalIF":0.0,"publicationDate":"2012-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.4161/biom.20866","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"31318839","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 30

Effect of cement fill ratio in loosening of hip implants. 水泥填充率对髋关节假体松动的影响。

Biomatter Pub Date : 2012-04-01 DOI: 10.4161/biom.20709

Elizabeth Gunn, Dinesh Gundapaneni, Tarun Goswami

引用次数: 15

Calcium orthophosphates and human beings: a historical perspective from the 1770s until 1940. 正磷酸钙与人类：从 1770 年代到 1940 年的历史视角。

Biomatter Pub Date : 2012-04-01 DOI: 10.4161/biom.21340

Sergey V Dorozhkin

{"title":"Calcium orthophosphates and human beings: a historical perspective from the 1770s until 1940.","authors":"Sergey V Dorozhkin","doi":"10.4161/biom.21340","DOIUrl":"10.4161/biom.21340","url":null,"abstract":"The historical development of a scientific knowledge on calcium orthophosphates from the 1770s until 1940 is described. Many forgotten and poorly known historical facts and approaches have been extracted from old publications and then they have been analyzed, systematized and reconsidered from the modern point of view. The chosen time scale starts with the earliest available studies of 1770s (to the best of my findings, calcium orthophosphates had been unknown before), passes through the entire 19th century and finishes in 1940, because since then the amount of publications on calcium orthophosphates rapidly increases and the subject becomes too broad. Furthermore, since publications of the second half of the 20th century are easily accessible, a substantial amount of them have already been reviewed by other researchers. The reported historical findings clearly demonstrate that the substantial amount of the scientific facts and experimental approaches have been known for very many decades and, in fact, the considerable quantity of relatively recent investigations on calcium orthophosphates is just either a further development of the earlier studies or a rediscovery of the already forgotten knowledge.","PeriodicalId":8891,"journal":{"name":"Biomatter","volume":"2 2","pages":"53-70"},"PeriodicalIF":0.0,"publicationDate":"2012-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/f6/f6/biom-2-53.PMC3549858.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"31319237","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Evaluation of silicon nitride as a wear resistant and resorbable alternative for total hip joint replacement. 氮化硅作为全髋关节置换术中耐磨可吸收替代物的评价。

Biomatter Pub Date : 2012-04-01 DOI: 10.4161/biom.20710

Johanna Olofsson, T Mikael Grehk, Torun Berlind, Cecilia Persson, Staffan Jacobson, Håkan Engqvist

{"title":"Evaluation of silicon nitride as a wear resistant and resorbable alternative for total hip joint replacement.","authors":"Johanna Olofsson, T Mikael Grehk, Torun Berlind, Cecilia Persson, Staffan Jacobson, Håkan Engqvist","doi":"10.4161/biom.20710","DOIUrl":"https://doi.org/10.4161/biom.20710","url":null,"abstract":"Many of the failures of total joint replacements are related to tribology, i.e., wear of the cup, head and liner. Accumulation of wear particles at the implants can be linked to osteolysis which leads to bone loss and in the end aseptic implant loosening. Therefore it is highly desirable to reduce the generation of wear particles from the implant surfaces. Silicon nitride (Si(3)N(4)) has shown to be biocompatible and have a low wear rate when sliding against itself and is therefore a good candidate as a hip joint material. Furthermore, wear particles of Si(3)N(4) are predicted to slowly dissolve in polar liquids and they therefore have the potential to be resorbed in vivo, potentially reducing the risk for aseptic loosening. In this study, it was shown that α-Si(3)N(4)-powder dissolves in PBS. Adsorption of blood plasma indicated a good acceptance of Si(3)N(4) in the body with relatively low immune response. Si(3)N(4) sliding against Si(3)N(4) showed low wear rates both in bovine serum and PBS compared with the other tested wear couples. Tribofilms were built up on the Si(3)N(4) surfaces both in PBS and in bovine serum, controlling the friction and wear characteristics.","PeriodicalId":8891,"journal":{"name":"Biomatter","volume":"2 2","pages":"94-102"},"PeriodicalIF":0.0,"publicationDate":"2012-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.4161/biom.20710","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"31410429","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 72