Bioscience of Microbiota, Food and Health最新文献

Effects of blackcurrant extract on indole and ammonia productions in an in vitro human fecal culture model. 黑加仑提取物对体外人体粪便培养模型中吲哚和氨生成的影响

IF 3.1 4区医学

Bioscience of Microbiota, Food and Health Pub Date : 2024-01-01 Epub Date: 2023-09-07 DOI: 10.12938/bmfh.2022-094

Nanami Ishiguro, Takayuki Hayashi, Miho Okayama, Taiki Yamaguchi, Mamiko Kohno, Hirosato Kawakami, Tohru Mitsunaga, Kohei Nakamura, Mizuho Inagaki

{"title":"Effects of blackcurrant extract on indole and ammonia productions in an in vitro human fecal culture model.","authors":"Nanami Ishiguro, Takayuki Hayashi, Miho Okayama, Taiki Yamaguchi, Mamiko Kohno, Hirosato Kawakami, Tohru Mitsunaga, Kohei Nakamura, Mizuho Inagaki","doi":"10.12938/bmfh.2022-094","DOIUrl":"10.12938/bmfh.2022-094","url":null,"abstract":"Blackcurrant is available as a traditional medicine in Europe. However, the detailed effects of blackcurrant on the human gut microbiota remain unknown. In this study, we investigated the prebiotic effects of a blackcurrant extract using a human fecal culture model in six healthy subjects. Feces were individually inoculated into a medium with or without the blackcurrant extract and then fermented for 48 hr under anaerobic conditions. The results obtained from analysis of samples from the fermented medium demonstrated that after 48 hr of fermentation, the pH of the medium with the blackcurrant extract was significantly decreased (control, 6.62 ± 0.20; blackcurrant extract, 6.41 ± 0.33; p=0.0312). A 16S rRNA gene sequencing analysis of the microbiota of the fermented medium showed a significant increase in the relative abundance of Bifidobacteriaceae. In measuring the concentrations of putrefactive components in the fermented medium, we found that the blackcurrant extract significantly reduced ammonia levels and displayed a tendency toward reduced indole levels. Our results suggest that blackcurrant extract could be a potential ingredient for relief of putrefactive components in the gut.","PeriodicalId":8867,"journal":{"name":"Bioscience of Microbiota, Food and Health","volume":null,"pages":null},"PeriodicalIF":3.1,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10767324/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"78560846","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Effect of magnesium oxide with probiotics on bowel movements in elderly orthopedic patients with chronic constipation: a retrospective chart review. 氧化镁加益生菌对老年骨科慢性便秘患者排便的影响：回顾性病历审查。

IF 3.1 4区医学

Bioscience of Microbiota, Food and Health Pub Date : 2024-01-01 Epub Date: 2023-09-06 DOI: 10.12938/bmfh.2023-040

Takahiko Nagamine

引用次数: 0

Antimicrobial resistance in food-associated Escherichia coli in Mexico and Latin America. 墨西哥和拉丁美洲与食物有关的大肠杆菌的抗菌药耐药性。

IF 3.1 4区医学

Bioscience of Microbiota, Food and Health Pub Date : 2024-01-01 Epub Date: 2023-06-29 DOI: 10.12938/bmfh.2023-022

Lorena Babines-Orozco, María Guadalupe Balbuena-Alonso, Edwin Barrios-Villa, Patricia Lozano-Zarain, Ygnacio Martínez-Laguna, Rosa Del Carmen Rocha-Gracia, Gerardo Cortés-Cortés

{"title":"Antimicrobial resistance in food-associated Escherichia coli in Mexico and Latin America.","authors":"Lorena Babines-Orozco, María Guadalupe Balbuena-Alonso, Edwin Barrios-Villa, Patricia Lozano-Zarain, Ygnacio Martínez-Laguna, Rosa Del Carmen Rocha-Gracia, Gerardo Cortés-Cortés","doi":"10.12938/bmfh.2023-022","DOIUrl":"10.12938/bmfh.2023-022","url":null,"abstract":"The World Health Organization (WHO) considers antimicrobial resistance to be one of the critical global public health priorities to address. Escherichia coli is a commensal bacterium of the gut microbiota in humans and animals; however, some strains cause infections and are resistant to antibiotics. One of the most common ways of acquiring pathogenic E. coli strains is through food. This review analyzes multidrug-resistant E. coli isolated from food, emphasizing Latin America and Mexico, and the mobile genetic elements (MGEs) responsible for spreading antibiotic resistance determinants among bacteria in different environments and hosts. We conducted a systematic search of the literature published from 2015 to 2022 in open access databases and electronic repositories. The prevalence of 11 E. coli pathotypes was described, with diarrheagenic E. coli pathotypes being the most frequently associated with foodborne illness in different Latin American countries, highlighting the presence of different antibiotic resistance genes mostly carried by IncF-type plasmids or class 1 integrons. Although the global incidence of foodborne illness is high, there have been few studies in Mexico and Latin America, which highlights the need to generate updated epidemiological data from the \"One Health\" approach, which allows monitoring of the multidrug-resistance phenomenon in E. coli from a common perspective in the interaction of human, veterinary, and environmental health.","PeriodicalId":8867,"journal":{"name":"Bioscience of Microbiota, Food and Health","volume":null,"pages":null},"PeriodicalIF":3.1,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10767319/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"88816716","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Microbial composition and metabolic profiles during machine-controlled intra-factory fermentation of cocoa beans harvested in semitropical area of Japan. 日本半热带地区收获的可可豆在机器控制的厂内发酵过程中的微生物组成和代谢概况。

IF 3.1 4区医学

Bioscience of Microbiota, Food and Health Pub Date : 2024-01-01 Epub Date: 2023-09-04 DOI: 10.12938/bmfh.2023-036

Hiroya Nishimura, Yuh Shiwa, Satoru Tomita, Akihito Endo

{"title":"Microbial composition and metabolic profiles during machine-controlled intra-factory fermentation of cocoa beans harvested in semitropical area of Japan.","authors":"Hiroya Nishimura, Yuh Shiwa, Satoru Tomita, Akihito Endo","doi":"10.12938/bmfh.2023-036","DOIUrl":"10.12938/bmfh.2023-036","url":null,"abstract":"Cocoa bean fermentation is typically performed in a spontaneous manner on farms in tropical countries or areas and involves several microbial groups. Metabolism by microbes markedly affects the quality of cocoa beans fermented and the chocolate produced thereof. The present study characterized the microbiota and their metabolic profiles in temperature- and humidity-controlled intra-factory cocoa fermentation in a semitropical area of Japan. Although environmental factors were uniform, the microbiota of cocoa beans subjected to intra-factory fermentation was not stable between tests, particularly in terms of the cell count levels and species observed. Fermentation was sometimes delayed, and fermenting microbes were present at very low levels after 24 hr of fermentation. Due to the unstable microbiota, the profiles of water-soluble compounds differed between tests, indicating the unstable qualities of the fermented cocoa beans. These results suggest the necessity of starter cultures not only in on-farm fermentation but also in machine-controlled intra-factory cocoa fermentation.","PeriodicalId":8867,"journal":{"name":"Bioscience of Microbiota, Food and Health","volume":null,"pages":null},"PeriodicalIF":3.1,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10767318/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"72929361","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Lactiplantibacillus plantarum 06CC2 upregulates intestinal ZO-1 protein and bile acid metabolism in Balb/c mice fed high-fat diet. 植物乳杆菌 06CC2 能上调高脂饮食 Balb/c 小鼠肠道 ZO-1 蛋白和胆汁酸代谢。

IF 3.1 4区医学

Bioscience of Microbiota, Food and Health Pub Date : 2024-01-01 Epub Date: 2023-07-31 DOI: 10.12938/bmfh.2023-002

Masao Yamasaki, Yuko Miyamoto, Kenjirou Ogawa, Kazuo Nishiyama, Chuluunbat Tsend-Ayush, Yiran Li, Tatsuya Matsusaki, Tomoki Nakano, Masahiko Takeshita, Yuo Arima

{"title":"Lactiplantibacillus plantarum 06CC2 upregulates intestinal ZO-1 protein and bile acid metabolism in Balb/c mice fed high-fat diet.","authors":"Masao Yamasaki, Yuko Miyamoto, Kenjirou Ogawa, Kazuo Nishiyama, Chuluunbat Tsend-Ayush, Yiran Li, Tatsuya Matsusaki, Tomoki Nakano, Masahiko Takeshita, Yuo Arima","doi":"10.12938/bmfh.2023-002","DOIUrl":"10.12938/bmfh.2023-002","url":null,"abstract":"The effects of Lactiplantibacillus plantarum 06CC2 (LP06CC2), which was isolated from a Mongolian dairy product, on lipid metabolism and intestinal tight junction-related proteins in Balb/c mice fed a high-fat diet (HFD) were evaluated. The mice were fed the HFD for eight weeks, and the plasma and hepatic lipid parameters, as well as the intestinal tight junction-related factors, were evaluated. LP06CC2 slightly reduced the adipose tissue mass. Further, it dose-dependently decreased plasma total cholesterol (TC). The HFD tended to increase the plasma level of endotoxin and suppressed intestinal ZO-1 expression, whereas a low LP06CC2 dose increased ZO-1 expression and tended to reduce the plasma lipopolysaccharide level. Furthermore, a low LP06CC2 dose facilitated a moderate accumulation of Lactobacillales, a significant decrease in Clostridium cluster IV, and an increase in Clostridium cluster XVIII. The results obtained from analyzing the bile acids (BAs) in feces and cecum contents exhibited a decreasing trend for secondary and conjugated BAs in the low LP06CC2-dose group. Moreover, a high LP06CC2 dose caused excess accumulation of Lactobacillales and failed to increase intestinal ZO-1 and occludin expression, while the fecal butyrate level increased dose dependently in the LP06CC2-fed mice. Finally, an appropriate LP06CC2 dose protected the intestinal barrier function from the HFD and modulated BA metabolism.","PeriodicalId":8867,"journal":{"name":"Bioscience of Microbiota, Food and Health","volume":null,"pages":null},"PeriodicalIF":3.1,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10767321/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"86315021","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Phylogenomic analysis in Latilactobacillus sakei by using polymorphisms detected by next-generation sequencing. 利用新一代测序检测的多态性分析酒井乳酸杆菌的系统基因组学。

IF 3.1 4区医学

Bioscience of Microbiota, Food and Health Pub Date : 2023-01-01 DOI: 10.12938/bmfh.2022-017

Chisato Nishiyama, Suguru Sekiguchi, Yu Sugihara, Minami Nishikawa, Natsu Makita, Tenta Segawa, Momoka Terasaki, Hiroki Takagi, Takashi Koyanagi

引用次数: 0

Consumption of yogurt fermented with Lactobacillus delbrueckii ssp. bulgaricus OLL1073R-1 augments serum antibody titers against seasonal influenza vaccine in healthy adults. 饮用用德氏乳杆菌发酵的酸奶。OLL1073R-1增强健康成人抗季节性流感疫苗的血清抗体滴度。

IF 3.1 4区医学

Bioscience of Microbiota, Food and Health Pub Date : 2023-01-01 DOI: 10.12938/bmfh.2022-037

Jun Hemmi, Seiya Makino, Takehiro Yokoo, Hiroshi Kano, Yukio Asami, Kazuyoshi Takeda, Yoshio Suzuki, Sachio Kawai, Isao Nagaoka, Keisuke Sawaki, Ko Okumura

{"title":"Consumption of yogurt fermented with Lactobacillus delbrueckii ssp. bulgaricus OLL1073R-1 augments serum antibody titers against seasonal influenza vaccine in healthy adults.","authors":"Jun Hemmi, Seiya Makino, Takehiro Yokoo, Hiroshi Kano, Yukio Asami, Kazuyoshi Takeda, Yoshio Suzuki, Sachio Kawai, Isao Nagaoka, Keisuke Sawaki, Ko Okumura","doi":"10.12938/bmfh.2022-037","DOIUrl":"https://doi.org/10.12938/bmfh.2022-037","url":null,"abstract":"Seasonal influenza is a major upper respiratory tract infection occurring in winter. Vaccination is the best method for preventing this infection. We conducted two randomized, double-blind, placebo-controlled trials to examine whether consumption of yogurt fermented with Lactobacillus delbrueckii ssp. bulgaricus OLL1073R-1, which has been reported to reduce the risk of catching the common cold, augments serum antibody titers against seasonal influenza vaccines. In the first trial, which included university students, serum antibody titers against influenza A (H3N2) and B viruses were significantly higher in the yogurt group than in the placebo group. According to the guidelines established by the European Medicines Agency (EMA) for the assessment of vaccines, the seroconversion rate and mean geometric increase of influenza A (H3N2) and seroprotection of influenza B met the criteria only in the yogurt group. In the second trial, which included healthy adults, serum antibody titers against influenza A (H1N1) and B viruses were significantly higher in the yogurt group than in the placebo group. The seroconversion rate and mean geometric increase of influenza B met the EMA criteria only in the yogurt group. Furthermore, the cumulative days of ill health, such as throat complaints, upper respiratory inflammation, and cold, were significantly lower in the yogurt group than in the placebo group. Therefore, daily intake of yogurt fermented with L. bulgaricus OLL1073R-1 could reduce the duration of symptoms caused by respiratory infections and act as a mucosal adjuvant enhancing acquired immune responses against vaccines, leading to the improvement of public health.","PeriodicalId":8867,"journal":{"name":"Bioscience of Microbiota, Food and Health","volume":null,"pages":null},"PeriodicalIF":3.1,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/a8/08/bmfh-42-073.PMC9816052.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10607723","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 3

Gut microbial stability in older Japanese populations: insights from the Mykinso cohort 日本老年人肠道微生物稳定性:来自Mykinso队列的见解

4区医学

Bioscience of Microbiota, Food and Health Pub Date : 2023-01-01 DOI: 10.12938/bmfh.2022-047

Satoshi WATANABE, Naofumi YOSHIDA, Kairi BABA, Hiroyuki YAMASAKI, Natsuko O. SHINOZAKI, Masato OGAWA, Tomoya YAMASHITA, Aya K. TAKEDA

{"title":"Gut microbial stability in older Japanese populations: insights from the Mykinso cohort","authors":"Satoshi WATANABE, Naofumi YOSHIDA, Kairi BABA, Hiroyuki YAMASAKI, Natsuko O. SHINOZAKI, Masato OGAWA, Tomoya YAMASHITA, Aya K. TAKEDA","doi":"10.12938/bmfh.2022-047","DOIUrl":"https://doi.org/10.12938/bmfh.2022-047","url":null,"abstract":"Gut microbiota imbalance plays an important role in the pathogenesis of various diseases. Here, we determined microbe–microbe interactions and gut microbiome stability in a Japanese population with varying body mass indices (BMIs) and enterotypes. Using 16S ribosomal RNA gene sequencing, we analyzed gut microbial data from fecal samples obtained from 3,365 older Japanese individuals. The individuals were divided into lean, normal, and obese groups based on their BMIs. They were further categorized according to their gut microbiota enterotypes: Bacteroides (enterotype B), Prevotella (enterotype P), and Ruminococcus (enterotype R). We obtained data on different host factors, such as age, BMI, and disease status, using a survey questionnaire evaluated by the Mykinso gut microbiome testing service. Subsequently, we evaluated the co-occurrence network. Individual differences in BMI were associated with differences in co-occurrence networks. By exploring the network topology based on BMI status , we observed that the network density was lower in the lean group than that in the normal group. Furthermore, a simulation-based stability analysis revealed a lower resistance index in the lean group than those in the other two groups. Our results provide insights into various microbe–microbe interactions and gut microbial stability and could aid in developing appropriate therapeutic strategies targeting gut microbiota modulation to manage frailty.","PeriodicalId":8867,"journal":{"name":"Bioscience of Microbiota, Food and Health","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"136373572","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Effects of the loss of maternal gut microbiota before pregnancy on gut microbiota, food allergy susceptibility, and epigenetic modification on subsequent generations. 妊娠前母体肠道菌群缺失对后代肠道菌群、食物过敏易感性和表观遗传修饰的影响。

IF 3.1 4区医学

Bioscience of Microbiota, Food and Health Pub Date : 2023-01-01 DOI: 10.12938/bmfh.2022-093

Shinta Aizawa, Takashi Uebanso, Takaaki Shimohata, Kazuaki Mawatari, Akira Takahashi

{"title":"Effects of the loss of maternal gut microbiota before pregnancy on gut microbiota, food allergy susceptibility, and epigenetic modification on subsequent generations.","authors":"Shinta Aizawa, Takashi Uebanso, Takaaki Shimohata, Kazuaki Mawatari, Akira Takahashi","doi":"10.12938/bmfh.2022-093","DOIUrl":"https://doi.org/10.12938/bmfh.2022-093","url":null,"abstract":"Maternal environments affect the health of offspring in later life. Changes in epigenetic modifications may partially explain this phenomenon. The gut microbiota is a critical environmental factor that influences epigenetic modifications of host immune cells and the development of food allergies. However, whether changes in the maternal gut microbiota affect the development of food allergies and related epigenetic modifications in subsequent generations remains unclear. Here, we investigated the effects of antibiotic treatment before pregnancy on the development of the gut microbiota, food allergies, and epigenetic modifications in F1 and F2 mice. We found that pre-conception antibiotic treatment affected the gut microbiota composition in F1 but not F2 offspring. F1 mice born to antibiotic-treated mothers had a lower proportion of butyric acid-producing bacteria and, consequently, a lower butyric acid concentration in their cecal contents. The methylation level in the DNA of intestinal lamina propria lymphocytes, food allergy susceptibility, and production of antigen-specific IgE in the F1 and F2 mice were not different between those born to control and antibiotic-treated mothers. In addition, F1 mice born to antibiotic-treated mothers showed increased fecal excretion related to the stress response in a novel environment. These results suggest that the maternal gut microbiota is effectively passed onto F1 offspring but has little effect on food allergy susceptibility or DNA methylation levels in offspring.","PeriodicalId":8867,"journal":{"name":"Bioscience of Microbiota, Food and Health","volume":null,"pages":null},"PeriodicalIF":3.1,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/7a/36/bmfh-42-203.PMC10315195.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10178196","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Development of a lactic acid bacteria strain that suppresses chronic inflammation and improves glucose and lipid metabolism. 乳酸菌菌株的发展，抑制慢性炎症和改善糖脂代谢。

IF 3.1 4区医学

Bioscience of Microbiota, Food and Health Pub Date : 2023-01-01 DOI: 10.12938/bmfh.2022-054

Takayuki Toshimitsu

{"title":"Development of a lactic acid bacteria strain that suppresses chronic inflammation and improves glucose and lipid metabolism.","authors":"Takayuki Toshimitsu","doi":"10.12938/bmfh.2022-054","DOIUrl":"https://doi.org/10.12938/bmfh.2022-054","url":null,"abstract":"Chronic inflammation caused by aging, obesity, and lifestyle disturbances can lead to the production of inflammatory cytokines and insulin resistance, reducing glucose and lipid metabolism. Lactic acid bacteria (LAB) have various bioactivities, and certain types of LAB have been reported to exhibit anti-inflammatory effects. We hypothesized that LAB strains, which can strongly induce the production of anti-inflammatory cytokines by immune cells in the intestinal tract, may improve glucose and lipid metabolism by suppressing chronic inflammation. We selected Lactiplantibacillus plantarum OLL2712 (OLL2712) from the LAB library owned by Meiji Co., Ltd. based on its ability to induce the production of interleukin-10 (IL-10), optimized the culture conditions of OLL2712 for industrial applications, and verified the efficacy of the strain in animal and clinical studies. The results showed that OLL2712 bacterial cells in the exponential phase had notably higher anti-inflammatory properties than the cells in the stationary phase and led to the inhibition of chronic inflammation and improvement of glucose and lipid metabolism in animal studies. Two randomized controlled trials consisting of healthy adults with elevated blood glucose levels or body mass indices (BMIs) also showed that the intake of OLL2712 suppressed the aggravation of chronic inflammation and improved glucose and lipid metabolism. This review identified a novel LAB strain that may contribute to diabetes and obesity prevention and demonstrated its clinical efficacy. In addition, the mechanism of action of this LAB strain through the intestinal immune system was partially elucidated, and the importance of optimizing the culture conditions of LAB was clarified.","PeriodicalId":8867,"journal":{"name":"Bioscience of Microbiota, Food and Health","volume":null,"pages":null},"PeriodicalIF":3.1,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/6e/eb/bmfh-42-003.PMC9816046.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10607724","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0