Biologia futuraPub Date : 2026-04-02DOI: 10.1007/s42977-026-00314-5
Abrorkhon Saitmuratov, Ayşe Nur Kafalı, Mehmet Zahit Yeken
{"title":"Unveiling lentil responses to salt stress and gibberellic acid: phenotypic, bioactive and enzymatic dynamics.","authors":"Abrorkhon Saitmuratov, Ayşe Nur Kafalı, Mehmet Zahit Yeken","doi":"10.1007/s42977-026-00314-5","DOIUrl":"https://doi.org/10.1007/s42977-026-00314-5","url":null,"abstract":"","PeriodicalId":8853,"journal":{"name":"Biologia futura","volume":" ","pages":""},"PeriodicalIF":1.5,"publicationDate":"2026-04-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147608113","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Biologia futuraPub Date : 2026-03-14DOI: 10.1007/s42977-026-00312-7
Maher Alnajjar, Endre Barta
{"title":"Leveraging large family analyses for more accurate de novo mutation detection.","authors":"Maher Alnajjar, Endre Barta","doi":"10.1007/s42977-026-00312-7","DOIUrl":"https://doi.org/10.1007/s42977-026-00312-7","url":null,"abstract":"<p><p>De novo mutations (DNMs), which arise in the offspring and are absent in the parents, are increasingly studied in farm animals with the advent of whole-genome sequencing (WGS). Variant calling after genome sequencing is a crucial step in modern genomics, and its accuracy directly influences subsequent genetic analyses, which are vital not only in breeding and human healthcare but also in functional genomic research. Yet, using only families with trios neglects the important shared information in the family and leads to an inaccurate determination of DNMs. Here, we show that using inheritance-based Whole Genome Sequencing (WGS) data analysis on a larger family is an effective way to identify DNMs in offspring accurately, and we present the first such study in rabbits.</p>","PeriodicalId":8853,"journal":{"name":"Biologia futura","volume":" ","pages":""},"PeriodicalIF":1.5,"publicationDate":"2026-03-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147455446","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Biologia futuraPub Date : 2026-03-13DOI: 10.1007/s42977-026-00313-6
Kriti Singh, Deepali Sambyal, J M Julka
{"title":"Metagenomic exploration of bacterial community shifts before, during, and after passage through earthworm Eutyphoeus waltoni.","authors":"Kriti Singh, Deepali Sambyal, J M Julka","doi":"10.1007/s42977-026-00313-6","DOIUrl":"https://doi.org/10.1007/s42977-026-00313-6","url":null,"abstract":"","PeriodicalId":8853,"journal":{"name":"Biologia futura","volume":" ","pages":""},"PeriodicalIF":1.5,"publicationDate":"2026-03-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147455392","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Biologia futuraPub Date : 2026-03-09DOI: 10.1007/s42977-025-00302-1
A F Rosiles-Ortega, M J Abraham-Juárez, F Jaimes-Miranda
{"title":"Protein-protein interaction detection in plants: from classical approaches to future perspectives.","authors":"A F Rosiles-Ortega, M J Abraham-Juárez, F Jaimes-Miranda","doi":"10.1007/s42977-025-00302-1","DOIUrl":"https://doi.org/10.1007/s42977-025-00302-1","url":null,"abstract":"","PeriodicalId":8853,"journal":{"name":"Biologia futura","volume":" ","pages":""},"PeriodicalIF":1.5,"publicationDate":"2026-03-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147389148","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Biologia futuraPub Date : 2026-03-01Epub Date: 2025-11-28DOI: 10.1007/s42977-025-00293-z
Tabish Ali Virk, Muhammad Zulqurnain Haider, Qasim Ali
{"title":"Combined use of proline and microbes on yield attributes, photosynthetic efficiency, water relations, nutrient acquisition and antioxidative defense mechanisms of fennel plants under drought conditions.","authors":"Tabish Ali Virk, Muhammad Zulqurnain Haider, Qasim Ali","doi":"10.1007/s42977-025-00293-z","DOIUrl":"10.1007/s42977-025-00293-z","url":null,"abstract":"<p><p>The aim of the study was the induction of water stress tolerance in the fennel (Foeniculum vulgare Mill.) by the combined proline (Pro) and bacterial strain BEB1 (BEB1) application as foliar spray. Arrangement of experiment was done in field as split-split plot in open natural environmental conditions. Deficit water supply significantly adversely affected the growth and yield of fennel plants. Foliar-applied different treatments significantly reduced the water stress adverse effects on the performance of fennel plants regarding growth and yield that found linked to improvement in water status of plants and better net photosynthetic activity of fennel plants in comparison to non-treated plants. Combined application of Pro and BEB1 better maintained the seed yield and growth of fennel plants found associated with reduced lipid peroxidation, improvement in antioxidative defence mechanism, maintenance of plant water relations through better osmotic adjustment by increased accumulation of different metabolites. The maintenance of better yield and biomass production of water-stressed fennel plants also found positively associated with increased uptake as well as translocation of mineral nutrients. The maximum increase (30, 35 and 36, 34%) in shoot and root fresh and dry biomasses respectively and a decrease (24.13, 23.01 and 25.75%) in LRMP, MDA and H<sub>2</sub>O<sub>2</sub> respectively, was found in plants sprayed with 1%Pro + BEB1. An increase of 41.43% in seed yield was recorded in fennel plants sprayed with 1%Pro + BEB1. Combined foliar spray of Pro and BEB1 was found better to increase tolerance against water stress for better yield by improving physio-biochemical mechanisms than their individual applications.</p>","PeriodicalId":8853,"journal":{"name":"Biologia futura","volume":" ","pages":"113-138"},"PeriodicalIF":1.5,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145628411","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Biologia futuraPub Date : 2026-03-01Epub Date: 2025-11-27DOI: 10.1007/s42977-025-00297-9
Nikolina A Matić, Marija V Vesović, Djordje P Božović, Milorad M Vujičić, Michal Goga, Aneta D Sabovljević, Marko S Sabovljević
{"title":"Nature-based solutions: the potential of bryophytes for snail repellency in lettuce crop production.","authors":"Nikolina A Matić, Marija V Vesović, Djordje P Božović, Milorad M Vujičić, Michal Goga, Aneta D Sabovljević, Marko S Sabovljević","doi":"10.1007/s42977-025-00297-9","DOIUrl":"10.1007/s42977-025-00297-9","url":null,"abstract":"<p><p>Damage in lettuce production caused by burgundy snails has led to an increased use of molluscicidal chemicals, which persist in both the lettuce and the substrate, and accumulate over time with undesirable outcomes in terms of mollusk pest control. Moreover, these chemicals also harm natural snail populations. In this study, the effects of selected bryophyte species extracts and their application concentrations were tested as natural snail repellents. Twelve bryophyte species, eight mosses, and four liverworts were randomly selected, and their ethanolic extracts were applied as burgundy snail repellents in lettuce. Significant antifeeding effects were observed for the liverworts Bazzania trilobata, Plagiochila asplenioides, and Porella platyphylla, as well as for the mosses Fontinalis antipyretica, Mnium stellare, and Neckera crispa. Among these, B. trilobata exhibited the strongest antifeeding effect without negatively impacting lettuce growth and development, as assessed through seed germination, hypocotyl length, and seedling total chlorophyll content. All bryophyte species with significant antifeeding i.e. repellent potential shared similar chemical profiles, characterized by high phenolic and triterpenoid contents and strong antioxidant capacity. The results obtained offer a nature-based solution in lettuce crop protection as well as an eco-friendly alternative in food production.</p>","PeriodicalId":8853,"journal":{"name":"Biologia futura","volume":" ","pages":"175-188"},"PeriodicalIF":1.5,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145628403","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Spatial analysis and niche overlap of two lapwing (Genus: Vanellus) species in the confluence of two biodiversity hotspots in South Asia.","authors":"Langtuk Terang, Vivek Chetry, Aditya Shankar Kataki, Anubhav Bhuyan, Kuladip Sarma","doi":"10.1007/s42977-025-00296-w","DOIUrl":"10.1007/s42977-025-00296-w","url":null,"abstract":"","PeriodicalId":8853,"journal":{"name":"Biologia futura","volume":" ","pages":"165-174"},"PeriodicalIF":1.5,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145562568","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Biologia futuraPub Date : 2026-03-01Epub Date: 2025-11-12DOI: 10.1007/s42977-025-00295-x
Ömer Faruk Kalkan, Abdulhamit Yildirim, Osman Aktaş, Zafer Şahin, Selcen Aydin Abidin, Ali Faruk Özyaşar, Abdullah Kaan Kurt, Samet Soner Küçükosman, İbrahim Uzun, İsmail Abidin
{"title":"Central administration of asprosin reduces baseline brain activity but does not attenuate 4-AP-induced epileptiform discharges: an in vivo electrophysiological study.","authors":"Ömer Faruk Kalkan, Abdulhamit Yildirim, Osman Aktaş, Zafer Şahin, Selcen Aydin Abidin, Ali Faruk Özyaşar, Abdullah Kaan Kurt, Samet Soner Küçükosman, İbrahim Uzun, İsmail Abidin","doi":"10.1007/s42977-025-00295-x","DOIUrl":"10.1007/s42977-025-00295-x","url":null,"abstract":"<p><p>In the current study, we investigated the effects of central asprosin administration on baseline brain activity and 4-aminopyridine (4-AP) induced epileptiform activity. Additionally, we examined the effects of asprosin on electrocorticography (ECoG) band powers. Forty-two male Wistar rats were divided into six groups as follows: sham, 4-AP (2.5 mg/kg i.p.), asprosin 20 nmol (i.c.v.), asprosin 50 nmol (i.c.v.), asprosin 50 nmol (i.c.v.) posttreatment, and asprosin 50 nmol (i.c.v.) pre-treatment. Recordings lasting 60-70 min were conducted for all groups under ketamine/xylazine (90/10 mg/kg) anesthesia. In the posttreatment group, asprosin was injected 20 min after the induction of epileptiform activity. In the pre-treatment group, asprosin was injected after baseline recordings, and following a 20-min pre-treatment period, 4-AP was administered. 4-AP alone induced epileptiform activity in all animals, peaking at approximately the 30th minute. Asprosin significantly reduced ECoG power at doses of 20 nmol and 50 nmol. Furthermore, both doses of asprosin reduced alpha, beta, delta, theta, and gamma band activity in ECoG recordings at various time points. However, asprosin pre- and posttreatment had no significant effect on 4-AP-induced epileptiform activity. These findings suggest that asprosin modulates cortical excitability under physiological conditions but is ineffective in attenuating induced epileptiform activity.</p>","PeriodicalId":8853,"journal":{"name":"Biologia futura","volume":" ","pages":"155-164"},"PeriodicalIF":1.5,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145494355","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Biologia futuraPub Date : 2026-03-01Epub Date: 2025-11-26DOI: 10.1007/s42977-025-00298-8
Lou W Kim, Victor Castillo, Alejandro Barbieri
{"title":"PI3K/PKB signaling network as a host target to enhance bacterial ingestion and clearance.","authors":"Lou W Kim, Victor Castillo, Alejandro Barbieri","doi":"10.1007/s42977-025-00298-8","DOIUrl":"10.1007/s42977-025-00298-8","url":null,"abstract":"<p><p>Antibiotic resistance, driven by the misuse of antibiotics and the slow pace of new drug development, has led to a global rise in multidrug-resistant bacteria (MDRB), posing a major public health challenge. Host-directed therapies that enhance innate immune responses offer promising alternatives to traditional antibiotics. This review focuses on the central role of the PI3K/PKB (Akt) signaling pathway in phagocytosis and bacterial inactivation across both primitive phagocytes, such as Dictyostelium discoideum, and mammalian immune cells. In Dictyostelium, PI3K/PKB signaling coordinates the maturation of phagosomes and the fusion of phagolysosomes, processes essential for bacterial killing. Similarly, in immune cells, this pathway regulates cytoskeletal remodeling, vesicle trafficking, and the degradation of microbes. Specific pathogens, including Mycobacterium tuberculosis and Salmonella, subvert PI3K/PKB to evade immune responses, highlighting the pathway's dual role in host defense and pathogen survival. Targeting PI3K/PKB signaling or its inhibitory regulators may enhance phagocytic efficiency and restore immune function. Thus, PI3K/PKB represents a critical module in innate immunity and a compelling target for next-generation antimicrobial strategies.</p>","PeriodicalId":8853,"journal":{"name":"Biologia futura","volume":" ","pages":"29-37"},"PeriodicalIF":1.5,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145602027","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}