R. Hindritiani, Felly Nazlia, Nadia Octavia, Trustia Rizqandaru, D. Puspitosari, K. Ruchiatan
{"title":"A Split-Face Comparative Study in Efficacy and Safety between the Combination of 4% Niacinamide and 4% Kojic Acid Cream versus 4% Hydroquinone Cream for Epidermal Melasma","authors":"R. Hindritiani, Felly Nazlia, Nadia Octavia, Trustia Rizqandaru, D. Puspitosari, K. Ruchiatan","doi":"10.20473/bikk.v35.2.2023.93-99","DOIUrl":"https://doi.org/10.20473/bikk.v35.2.2023.93-99","url":null,"abstract":"Background: Melasma is a hyperpigmentation disorder that affects the quality of life, especially in women. Hydroquinone has remained the mainstay of melasma treatment. However, its safety for long-term usage became a great concern. Combination therapy, such as niacinamide and kojic acid, can be used as an alternative melasma treatment due to different mechanisms of action and synergism. Purpose: The aim of this study was to compare the efficacy and safety of a combination of 4% niacinamide and 4% kojic acid (N-K) vs. 4% hydroquinone (HQ) in epidermal melasma. Methods: This was a randomized, double blind, clinical study on 13 female epidermal melasma patients at the Cosmetic Dermatology Outpatient Clinic of Dr. Hasan Sadikin Hospital, Bandung. Patients received two creams, a combination of N-K and HQ, for split-face therapy, regardless of the sides of the face. All patients were followed up at 4 and 8 weeks. The clinical efficacy was assessed for skin lightening effects using a spectrophotometer (L* value) and the melasma area severity index (MASI). Adverse effects were assessed in all patients. Result: Both the N-K and HQ groups showed significant improvement in skin lightening and MASI scores on week 8 (p <0.05). There was no statistically significant difference in efficacy between the N-K and HQ groups (p >0.05). None of the patients in the N-K group complained of any adverse effects. Whereas in the HQ group, 23.07% presented with pruritus and mild erythema.","PeriodicalId":8792,"journal":{"name":"Berkala Ilmu Kesehatan Kulit dan Kelamin","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-07-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"82500034","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
M. K. Khamdan, Yuri Widia, R. Setiabudi, Evy Ervianti
{"title":"Impacts of Clinical and Demographical Aspects on the Duration of Pytiriasis Versicolor","authors":"M. K. Khamdan, Yuri Widia, R. Setiabudi, Evy Ervianti","doi":"10.20473/bikk.v35.2.2023.107-115","DOIUrl":"https://doi.org/10.20473/bikk.v35.2.2023.107-115","url":null,"abstract":"Background: Pityriasis versicolor (PV) or tinea versicolor is a superficial fungal infection characterized by macules on the skin. It is generally caused by the fungus Malassezia. PV is found throughout the world, especially in tropical countries. Generally, this infection is influenced by humidity, hyperhidrosis, and population density around the world. One of the ways to establish PV is through the KOH examination. Purpose: Evaluating the correlation between the clinical and demographic factors and the duration of illness of outpatient PV patients of the Mycology Division of Dermatology and Venereology Department at Dr. Soetomo General Academic Hospital from 2018 to 2020. Methods: This is an observational analytic study based on medical records at the outpatient clinic of Mycology Division of the Dermatology and Venereology Department of Dr. Soetomo General Academic Hospital. The data was collected in October 2021. The chi-square test is used to analyze the data in this study. Result: 216 PV patients’ data was collected. Most gender was male, most age group was 20-60, most weight group was 51 – 60 kg, most regional origin was from Surabaya, and most duration of infection was <3 months. In this study, topical and systemic treatment of this disease had a significant relationship with patients’ duration of illness (topical p=0.05; systemic p=0.026). Conclusion: Topical and systemic treatment of this disease has a significant relationship with the duration of illness in PV patients.","PeriodicalId":8792,"journal":{"name":"Berkala Ilmu Kesehatan Kulit dan Kelamin","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-07-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"81740457","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Gabriel Rio Widipriyatama, L. Dewanti, Sylvia Anggraeni, Damayanti
{"title":"Clinical Profile of Contact Dermatitis Patients at the Allergy-Immunology Division of Dermatology and Venereology Outpatient Clinic","authors":"Gabriel Rio Widipriyatama, L. Dewanti, Sylvia Anggraeni, Damayanti","doi":"10.20473/bikk.v35.2.2023.100-106","DOIUrl":"https://doi.org/10.20473/bikk.v35.2.2023.100-106","url":null,"abstract":"Background: Contact dermatitis is an inflammatory skin response that can be caused by several things. This inflammatory reaction is most often caused by external compounds that become allergens or irritants to the body. Purpose: To evaluate the clinical profile of contact dermatitis patients at the allergy-immunology division of dermatology and venereology outpatient clinic of Dr. Soetomo general academic hospital. Methods: The sampling technique used in this study is a total sampling technique and was processed with Excel descriptively. Result: The most frequent age group diagnosed with contact dermatitis was the 20–45-year-old age group (45.5%). The most frequent gender was female (72.2%). The most frequent occupation was private employee (30.8%). The most frequent suspected causal factor was cosmetics (35.2%). Itching was the most common type of patient complaint (44.1%). Face was the most frequent location (30.8%). Erythematous macules were the most frequent clinical manifestation (45.9%). The diagnosis of contact dermatitis was divided into allergic contact dermatitis ACD (60.4%) and irritant contact dermatitis ICD (39.6%). The most frequent topical therapy was corticosteroid (53.2%). Meanwhile, the most systemic therapy is antihistamine (73.8%). Conclusion: ACD is more prevalent than ICD and is more prevalent in women between the ages of 20 and 45. The most prevalent occupation distribution is among private employees. Cosmetics are the most frequently suspected cause factor. Itch is the most common patient complaint. The face is where contact dermatitis occurs most frequently. Erythematous macules are the most frequent clinical symptom. Corticosteroids and antihistamines are the most commonly given medication.","PeriodicalId":8792,"journal":{"name":"Berkala Ilmu Kesehatan Kulit dan Kelamin","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-07-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"85132098","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Review Article: Skin Condition and Skin Care in Premature Infants","authors":"Yuri Widia, B. Rosdiana","doi":"10.20473/bikk.v35.1.2023.67-73","DOIUrl":"https://doi.org/10.20473/bikk.v35.1.2023.67-73","url":null,"abstract":"Background: The majority of newborn skin care recommendations focus on concerns for healthy, full-term infants. Compared to mature infants, the skin of premature infants, those who are born at the gestational age of 37 weeks, is more vulnerable to injury, transepidermal water loss (TEWL), and transepidermal intoxication. There are no established guidelines for premature infant skin care. Discussion and review regarding this topic are needed. Purpose: To review the literature on skin conditions and skin care in premature infants. Review: The barrier function of premature skin is significantly compromised because the stratum corneum does not fully mature until late in the third trimester. Premature infants have immature skin with impaired barrier function characterized by high TEWL, increased absorption of chemicals, and increased risk of infection. Some particular issues in premature infant skin are controlling TEWL, avoiding mechanical damage, proper sterilization to control infection, awareness of percutaneous drug toxicity, appropriate bathing and umbilical cord care, and appropriate management of skin problems. Conclusion: Premature infant skin is more vulnerable due to immature development. Skin care for premature infants requires careful attention.","PeriodicalId":8792,"journal":{"name":"Berkala Ilmu Kesehatan Kulit dan Kelamin","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-03-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"80606640","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Ester Chateline Susanto, T. Setyaningrum, Arifa Mustika, L. Astari
{"title":"Chemical Peeling in Skin-Aging Patients: A Retrospective Study","authors":"Ester Chateline Susanto, T. Setyaningrum, Arifa Mustika, L. Astari","doi":"10.20473/bikk.v35.1.2023.6-14","DOIUrl":"https://doi.org/10.20473/bikk.v35.1.2023.6-14","url":null,"abstract":"Background: Skin aging is a degenerative process that involves a decrease in the structure and function of skin cells and theextracellular matrix due to intrinsic and extrinsic factors. Chemical peeling is one of the skin aging treatments that involvesskin ablation using chemical agents. Purpose: To evaluate the profile of skin-aging patients treated with chemical peeling atthe Dermatology and Venereology Outpatient Unit of Dr. Soetomo General Hospital Surabaya from January throughDecember 2019. Methods: The data were obtained from patients’ medical records through a total sampling technique, whichconsisted of age, gender, occupation, history taking, physical examination, diagnosis, therapeutic agents, follow-up frequency,and therapeutic result. Result: The study included 37 patients, the majority of whom were between the ages of 46 and 55(35.1%), female (100%), and private employees (32.4%). In history taking, patients’ main complaint is dull skin (94.6%), withthe risk factor of sun exposure (97.3%) and the history of sunscreen usage (81.1%). Pigmentary changes were found in allpatients (100%). The most common diagnoses are photoaging Glogau II and Glogau III, found in 15 patients (40.5%),respectively. The common priming agents were sunscreen (97.3%), cleanser (94.6%), and 8% glycolic acid (75.7%). Themajority of patients (62.2%) received 20% glycolic acid as a peeling agent and sunscreen (86.5%) as a post-peeling agent.The majority of patients (43.2%) did not follow up. Glogau II photoaging (57.1%) was the main therapeutic result.Conclusion: Proper chemical peeling procedures and patients compliance are important factors to improve therapeuticoutcomes.","PeriodicalId":8792,"journal":{"name":"Berkala Ilmu Kesehatan Kulit dan Kelamin","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-03-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"81350236","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
F. Prakoeswa, Ratih Pramuningtyas, Rully Setia Agus Dimawan
{"title":"The Pattern of Pediatric Parasitic Skin Diseases in a Secondary Hospital in East Java: A Retrospective Study","authors":"F. Prakoeswa, Ratih Pramuningtyas, Rully Setia Agus Dimawan","doi":"10.20473/bikk.v35.1.2023.52-56","DOIUrl":"https://doi.org/10.20473/bikk.v35.1.2023.52-56","url":null,"abstract":"Background: Epidermal parasitic skin diseases (EPSDs) are a group of neglected infectious diseases caused by parasites that infect the upper layer of the skin. A parasitic infection of the skin is caused by small insects or worms that burrow into the skin to live there or lay their eggs. EPSDs are a public health issue and can occur in children of all ages. Purpose: This study aims to describe the pattern and incidences of parasitic skin infections in children. Methods: This is a cross-sectional study utilizing medical records from the Dermatology and Venereology Clinic of Dr. Harjono Ponorogo General Public Hospital from 2016 to 2020. Result: Our study showed that, of the 1426 children brought to our clinic, parasitic infection was the second most common skin disease found in children with a prevalence of 27.1%. Parasitic infection in children was dominated by males with a proportion of 69.7%, and occurred mostly in the ≥13-year-old age group. Among all ages, scabies is the most frequent parasitic infection found, followed by cutaneous larva migrant (CLM) and pediculosis. Conclusion: The prevalence of EPSDs is increasing with age and is more common in males. This high prevalence is probably due to increased intensity of contact with other people, decreased parental care, and low socio-economic status.","PeriodicalId":8792,"journal":{"name":"Berkala Ilmu Kesehatan Kulit dan Kelamin","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-03-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"85972202","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Andre Yuindartanto, Sawitri, Astindari, Cita Rosita Sigit Prakoeswa, Damayanti, Sylvia Anggraen, M. Umborowati, I. Zulkarnain, M. Listiawan, A. Hidayati
{"title":"Occupational Contact Dermatitis Risk Factors on Healthcare Workers Isolation Ward During the COVID-19 Pandemic","authors":"Andre Yuindartanto, Sawitri, Astindari, Cita Rosita Sigit Prakoeswa, Damayanti, Sylvia Anggraen, M. Umborowati, I. Zulkarnain, M. Listiawan, A. Hidayati","doi":"10.20473/bikk.v35.1.2023.27-39","DOIUrl":"https://doi.org/10.20473/bikk.v35.1.2023.27-39","url":null,"abstract":"Background: After a history of exposure to the suspected material and a thorough physical examination, the diagnosis of occupational contact dermatitis (OCD) is commonly suspected. During the initial consultation, essential information involving the above is frequently neglected. Purpose: To evaluate the clinical manifestations of OCD cases in health workers and analyze the factors that influence OCD cases in health workers at the isolation ward of Dr. Soetomo Surabaya Hospital during the COVID-19 pandemic. Methods: The sample selection was done through purposive sampling. Accessible population that met the inclusion criteria and did not have exclusion criteria were included as research samples. The target population was healthcare workers in the Special Isolation Ward of Dr. Soetomo Hospital Surabaya. The accessible population was healthcare workers who performed hand hygiene activities and used Personal Protective Equipment (PPE) in the Special Isolation Ward of Dr. Soetomo Hospital Surabaya. The research subjects were healthcare workers who worked in the Special Isolation Ward. Result: The research results showed a strong and significant correlation between atopic history and the occurrence of contact dermatitis due to poor skin barrier function and decreased tolerance. The study also found that there was no significant correlation between atopic history and the severity level of OCD. There was a significant difference in transepidermal water loss (TEWL) values in the lesion and non-lesion areas, both on the palmar and dorsal aspects of the hand. Moisturizer is an important component in managing hand dermatitis as it can repair and maintain the skin's protective barrier. Conclusion:","PeriodicalId":8792,"journal":{"name":"Berkala Ilmu Kesehatan Kulit dan Kelamin","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-03-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"82380042","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Aprilin Krista Devi, M. Umborowati, Sylvia Anggraeni, D. Damayanti, C. Prakoeswa
{"title":"Henoch-Schonlein Purpura in Adult with Gastrointestinal and Renal Involvement","authors":"Aprilin Krista Devi, M. Umborowati, Sylvia Anggraeni, D. Damayanti, C. Prakoeswa","doi":"10.20473/bikk.v35.1.2023.74-80","DOIUrl":"https://doi.org/10.20473/bikk.v35.1.2023.74-80","url":null,"abstract":"Background: The pathogenesis of Henoch-Schonlein Purpura (HSP), a multisystem organ-involved small vessel vasculitis, is unknown. HSP is more common in youngsters than in adults. HSP is associated with a history of malignancies, medications, vaccinations, and upper respiratory tract infections. Painful purpura, arthritis, stomach discomfort, and renal involvement are symptoms that may be seen in HSP patients. Adult patients had a much higher rate of renal involvement than children. Purpose: To report a case of HSP in an adult with gastrointestinal and renal involvement. Case: A 45-year-old man complained of an arm, leg, and waist rash for two weeks before admission to the hospital. He also has stomach pains, nausea, and vomiting to deal with. His symptoms have just appeared now for the first time. During a renal function test, blood urea nitrogen (BUN) and creatine serum levels rose. On a urinalysis, proteinuria and microscopic hematuria were found. Leucocytoclastic vasculitis was discovered during the histopathology investigation. HSP diagnosis was based on the ACR and ICC criteria. The patient was given 3x2 tablets of 0.5 mg dexamethasone, 3x2 tablets of cetirizine, 2x10 mg lisinopril, 2x50 mg ranitidine injection, and 2 grams ceftriaxone. Discussion: The clinical symptoms of HSP are used to make the diagnosis. In the vast majority of instances, the treatment is only supportive therapy. Corticosteroid usually are usually used for HSP with multisystem organ involvement to reduce pain severity and faster resolution of renal manifestation. Conclusion: Follow up on renal function is needed to monitor the worsening of renal disease.","PeriodicalId":8792,"journal":{"name":"Berkala Ilmu Kesehatan Kulit dan Kelamin","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-03-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"91513809","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Profile of Skin Tumors at Dr. Zainoel Abidin General Hospital Dermatology and Venerology Outpatient Clinic in 2017 – 2021 : A Retrospective Study","authors":"Wahyu Lestari, Nanda Earlia Fitria, Sitti Hajar, Mimi Maulida","doi":"10.20473/bikk.v35.1.2023.40-45","DOIUrl":"https://doi.org/10.20473/bikk.v35.1.2023.40-45","url":null,"abstract":"Background: Skin tumors are swellings caused by proliferation or failure of cell death mechanisms. Based on the type of growth, skin tumors are divided into benign tumors and malignant tumors. Purpose: To investigate the incidence of skin tumors in Dr. Zainoel Abidin General Hospital outpatient clinic. Methods: This study is a descriptive study with total sampling. The diagnosis of skin tumors is assessed based on medical records filled by Dr. Zainoel Abidin General Hospital Dermatovenerologist in January 2017-September 2021. Result: The results showed patients diagnosed with benign skin tumors had as many as 360 subjects and malignant tumors had as many as 4 samples. The majority of women are affected by benign and malignant skin tumors. Based on the age of benign tumors dominated by the age of 22-45 years while in malignant tumors dominated by 45-64 years. The majority of the sample comes from Banda Aceh, based on where the most of them reside. Based on the size of lesions, benign tumors are dominated by lesions that are less than 0.5 cm in size, while malignant tumors are dominated by lesions that are larger than 0.5 cm in size. Based on the presence and absence of recursion the entire dominant sample has no recursion. Based on the physical treatment in benign tumors are dominated by electrocautery action while malignant tumors are the same number between general surgery and FNAB. Conclusion: most of the skin tumors found in Dr. Zainoel Abidin General Hospital dermatology and venerology outpatient clinic are benign","PeriodicalId":8792,"journal":{"name":"Berkala Ilmu Kesehatan Kulit dan Kelamin","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-03-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"84445671","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Alvian Arifin Saiboo, Cita Rosita Sigit Prakoeswa, D. Indramaya, A. Hidayati, Damayanti, Rahmadewi, B. Utomo, Frizka Eliza
{"title":"Characteristics and Clinical Profile of Vitiligo Patients in Dermatology and Venereology Outpatient Clinic Unit at Dr. Soetomo General Academic Hospital Surabaya","authors":"Alvian Arifin Saiboo, Cita Rosita Sigit Prakoeswa, D. Indramaya, A. Hidayati, Damayanti, Rahmadewi, B. Utomo, Frizka Eliza","doi":"10.20473/bikk.v35.1.2023.1-5","DOIUrl":"https://doi.org/10.20473/bikk.v35.1.2023.1-5","url":null,"abstract":"Background: Vitiligo is a depigmentation disorder characterized by the progressive loss of melanocytes from the epidermis and hair follicles. Vitiligo affects all age groups and is defined by acquired, idiopathic, progressive, different-sized, circumscribed, milky white depigmentation. Characteristics and clinical patterns of vitiligo will also help to understand the pathogenesis of the disease. Purpose: The aim of this study is to evaluate the characteristics profile and clinical features of vitiligo patients. Methods: The research material was taken from the medical record of vitiligo patients in the Division of Cosmetics Outpatient Clinic Dermatovenerelogy Dr. Soetomo General Hospital Surabaya from 2018-2020. Result: This study was obtained by a number of new vitiligo patients 115 (0.3%) of the total number of new outpatient clinic visits of Dermatovenereology Dr. Soetomo General Hospital Surabaya. The majority of the gender is female (53.9%), late adolescence (26.96%), students (25.22%), and the onset of vitiligo 1-5 years (30.43%). The most common risk factors were idiopathic (51.3%) and clinical types are non-segmental vitiligo (53.04%). Conclusion: Vitiligo predominantly affects in females with active age groups of 17-25 years old, and students.","PeriodicalId":8792,"journal":{"name":"Berkala Ilmu Kesehatan Kulit dan Kelamin","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-03-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"89052765","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}