Avian Pathology最新文献

{"title":"The host protein CCT8 interacts with PB2 protein of H9N2 AIV and facilitates virus replication.","authors":"Yiqin Cai, Ye Liu, Guihu Yin, Jianing Hu, Zichen Gao, Xinyu Guo, Ruiying Wang, Meng Zhong, Qingtao Liu, Xiuli Feng","doi":"10.1080/03079457.2025.2476511","DOIUrl":"10.1080/03079457.2025.2476511","url":null,"abstract":"<p><strong>Research highlights: </strong>The host protein CCT8 interacts with the influenza virus protein PB2.The CCT8 gene is upregulated during influenza virus infection.Knockdown of CCT8 inhibits viral proliferation.Elevated expression of CCT8 facilitates viral proliferation.</p>","PeriodicalId":8788,"journal":{"name":"Avian Pathology","volume":" ","pages":"530-540"},"PeriodicalIF":2.5,"publicationDate":"2025-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143708332","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Epidemiological investigation and drug resistance analysis of avian pathogenic <i>Escherichia coli</i> (APEC) of Wenchang chickens in Hainan, China.","authors":"Rui Tian, Feng Xie, Xin Wang, Lei Dai, Jinxiu Wang, Yuqing Liu, Chengxin Zhao, Qingxia Li, Wei Zhang","doi":"10.1080/03079457.2024.2447296","DOIUrl":"10.1080/03079457.2024.2447296","url":null,"abstract":"<p><strong>Research highlights: </strong>Type O8 is the most prevalent serotype of APEC isolated from Wenchang chicken embryos (Hainan, China).The isolates were more than 90% resistant to erythromycin, amoxicillin, ampicillin, and tetracycline.19.2% of the isolates were multi-resistant to more than 14 antibiotics.APEC of the same serotype isolated from Hainan Wenchang embryos have close relationships in the evolutionary tree of the core genome.</p>","PeriodicalId":8788,"journal":{"name":"Avian Pathology","volume":" ","pages":"398-410"},"PeriodicalIF":2.5,"publicationDate":"2025-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142881065","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Deletion of <i>ttrA</i> and <i>pduA</i> genes in <i>Salmonella enterica</i> serovars induce a comparable immune response to wild-type infection in different chicken lineages.","authors":"Túlio Spina de Lima, Mauro de Mesquita Souza Saraiva, Adriana Maria de Almeida, Taisa Santiago Ferreira, Lucas Bocchini Rodrigues Alves, Viviane Amorim Ferreira, Oliveiro Caetano de Freitas Neto, Paul Andrew Barrow, Angelo Berchieri Junior","doi":"10.1080/03079457.2025.2457095","DOIUrl":"10.1080/03079457.2025.2457095","url":null,"abstract":"<p><strong>Research highlights: </strong><i>ttrA</i> and <i>pduA</i> double mutants in <i>Salmonella</i> provoke a similar immune response.SE elicited more intense immune responses than STM.The immune response in the broiler was more intense than in other lineages.</p>","PeriodicalId":8788,"journal":{"name":"Avian Pathology","volume":" ","pages":"464-475"},"PeriodicalIF":2.5,"publicationDate":"2025-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142999459","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Morphological and molecular characterization of avian trypanosomes in domestic chickens (<i>Gallus gallus domesticus</i>) in Southeast Asia and review of the parasite morphometry in different avian hosts.","authors":"Pornchai Pornpanom, Gediminas Valkiūnas, Surya Paudel","doi":"10.1080/03079457.2025.2462628","DOIUrl":"10.1080/03079457.2025.2462628","url":null,"abstract":"<p><strong>Research highlights: </strong>The prevalence of trypanosomes in chickens is high.The first report of <i>Trypanosoma avium</i> in chickens with evidence of species identification.The first report of morphological and molecular characteristics of <i>Trypanosoma calmettei</i>.A cheap and quick buffy coat method is helpful for screening trypanosomes.</p>","PeriodicalId":8788,"journal":{"name":"Avian Pathology","volume":" ","pages":"489-497"},"PeriodicalIF":2.5,"publicationDate":"2025-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143121953","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Investigation of Dietary Eubiotic Supplementation on the Growth Performance and Gut Health Parameters in Broiler Chicks Challenged with <i>Eimeria</i> spp.: A Pilot Study.","authors":"Tilemachos Mantzios, Dimitrios Galamatis, Ioanna Stylianaki, Ioannis Panitsidis, Konstantinos Kiskinis, Elias Papadopoulos, Ilias Giannenas, Vasilios Tsiouris","doi":"10.1080/03079457.2025.2523883","DOIUrl":"https://doi.org/10.1080/03079457.2025.2523883","url":null,"abstract":"<p><p>Coccidiosis is a major challenge for the poultry industry, often leading to reduced performance, gut damage, and increased mortality. This study explores the efficacy of a phytogenic and prebiotic additive combination (PPB), containing inulin, β-glucans, vitamin C, and layer covered essential oils from oregano and cinnamon, as a dietary supplement in broiler chicks experimentally with <i>Eimeria</i> spp. A total of 288 broiler chicks (Ross®308) were randomly allocated into four treatment groups (6 replicates/group): NEG: the negative control (basal diet), INF: challenged by <i>Eimeria</i> spp. at 14^th days of age (basal diet), PPB: challenged by <i>Eimeria</i> spp, (basal diet, PPB supplementation) and SAL: challenged by <i>Eimeria</i> spp. (basal diet, salinomycin supplementation). Broiler performance, oocyst shedding, lesion score, histomorphometry, claudin-3 expression, and lymphocytic infiltration in the intestine were assessed. The challenge affected body weight (BW), average daily weight gain (ADWG), and feed conversion ratio (FCR), with the INF group exhibiting significantly poorer performance compared to the NEG and supplemented groups (p ≤ 0.05). Oocyst per gram (OPG) counts were significantly higher (p ≤ 0.05) in the INF group than in the PPB and SAL groups at all timepoints, while anticoccidial index (ACI) and total macroscopic lesion scores (TMLS) confirmed the protective effect of both interventions. Histopathological examination revealed that infection induced marked epithelial damage across intestinal segments. Immunohistochemical analysis demonstrated (p ≤ 0.05) elevated Claudin-3 expression in the duodenum and ileum of INF birds. In conclusion, the dietary supplementation with PPB provided protective effects against <i>Eimeria</i> infection in broiler chickens, comparable to salinomycin.RESEARCH HIGHLIGHTS PPB effectively mitigated <i>Eimeria</i> spp. infection in broilers.PPB and salinomycin reduced oocyst excretionOocyst excretion was highest in the INF groupPPB was as effective as salinomycin.</p>","PeriodicalId":8788,"journal":{"name":"Avian Pathology","volume":" ","pages":"1-39"},"PeriodicalIF":2.5,"publicationDate":"2025-06-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144332406","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"New Method for Early Detection of Gut Health Issues in Broilers.","authors":"Kirsten van Hees, Reinier van Velzen, Joost Thijssen, Lucas Hofmans, Remco Dijkman, Richard Ducatelle, Robert Jan Molenaar","doi":"10.1080/03079457.2025.2521354","DOIUrl":"https://doi.org/10.1080/03079457.2025.2521354","url":null,"abstract":"<p><strong>Research highlights: </strong>Flocks differ in levels for Lactobacillales, Lachnospiraceae and Ruminococcaceae.Gut Damage Ratio between broilers with or without gut health problems differ.Results of both assays in broilers of 21 days of age relate significantly to SW.</p>","PeriodicalId":8788,"journal":{"name":"Avian Pathology","volume":" ","pages":"1-21"},"PeriodicalIF":2.5,"publicationDate":"2025-06-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144332407","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Pathogenicity of FAdV-D serotype 2 in broiler and layer chicks.","authors":"Amr M Geneedy, Hatem S Abd El-Hamid, Hany F Ellakany, Ahmed R Elbestawy, Ahmed H Salaheldin, Ahmed E Noreldin, Ayman H Abd El-Aziz, Fares El-Khyate, Ahmed R Gado","doi":"10.1080/03079457.2025.2507023","DOIUrl":"https://doi.org/10.1080/03079457.2025.2507023","url":null,"abstract":"<p><p>Eighty, 1-day-old (DO) broiler chicks and 80 1-DO male layer chicks were experimentally infected with two isolates of fowl adenovirus D <b>(</b>FAdV-D) serotype 2 isolated from broiler chickens suffering inclusion body hepatitis (IBH) (accession numbers ON603311 and ON603320). Clinical observation was performed up to 28-DO, and samples from the liver, pancreas, kidneys, spleen, thymus, and bursa of Fabricius were collected for histopathological examination. Furthermore, FAdV-D viral shedding was tested up to 21DO. Serological response to IBH (FAdV-D) through enzyme-linked immunosorbent assay (ELISA) and blood biochemical analysis, as well as polymerase chain reaction (PCR) testing for some innate immune response parameters (interleukins and cytokines) to IBH were applied. Also, immune response of chicks to avian influenza and Newcastle disease vaccines was evaluated using the haemagglutination inhibition (HI) test. No mortality was observed following experimental infection of either broiler or layer chicks with FAdV-D serotype 2 isolates, despite the clearly evidenced histopathological damage in the liver, pancreas, kidneys, spleen, thymus, and bursa of Fabricius. Viral shedding extended to 21DO. Neither isolate could induce serological response, but both elevated the interleukins and cytokines. In conclusion, broilers were more susceptible to IBH-FAdV infection than layer chicks. FAdV-D serotype 2, which causes IBH, had an immunosuppressive effect on chickens.</p>","PeriodicalId":8788,"journal":{"name":"Avian Pathology","volume":" ","pages":"1-13"},"PeriodicalIF":2.5,"publicationDate":"2025-06-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144324393","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Fowl adenoviruses (FAdVs) in Iran between 2020-2022: the first comprehensive phylogenetic study.","authors":"Ali Hojabr Rajeoni, Hossein Hosseini, Hamideh Najafi, Arash Ghalyanchilangeroudi","doi":"10.1080/03079457.2025.2520361","DOIUrl":"https://doi.org/10.1080/03079457.2025.2520361","url":null,"abstract":"<p><p>Inclusion Body Hepatitis (IBH) outbreaks have been reported globally over the past two decades, predominantly affecting broiler flocks and resulting in significant economic losses due to increased mortality and diminished production performance. In Iran, fowl adenovirus (FAdV) infections have been circulating for several years, with recurrent reports of clinical cases suggesting IBH and hepatitis-hydropericardium Syndrome (HHS) in commercial poultry operations. In response to these concerns, the present study was conducted to comprehensively characterize circulating FAdV strains in Iranian poultry farms over a three-year period.A total of 200 pooled liver samples were collected from 200 broiler flocks that exhibited clinical signs consistent with IBH/HHS. Partial amplification and sequencing of the hexon gene were performed to detect and genotype the FAdV strains. The phylogenetic analysis assigned 66.32% of the detected strains to FAdV-D, 16.32% to FAdV-C, 11.22% to FAdV-E, and 6.12% to FAdV-B. Notably, this investigation provided the first genomic evidence of FAdV serotype 5 in Iran. Within the FAdV-C group, both serotypes 4 and 10 were identified. Additionally, serotype 6, closely related (98% nucleotide identity) to a Chinese reference strain, was reported for the first time in Iran. Given the high diversity of FAdV serotypes, continued vaccination of broiler breeders using vaccines that cover the strains circulating in the country is recommended. Monitoring broilers and broiler breeders remain essential for effective disease control and prevention.</p>","PeriodicalId":8788,"journal":{"name":"Avian Pathology","volume":" ","pages":"1-19"},"PeriodicalIF":2.5,"publicationDate":"2025-06-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144301118","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The role of YbdO in regulating acid resistance and biofilm formation in avian pathogenic <i>Escherichia coli</i>.","authors":"Lumin Yu, Linan Xu, Yuzhong Zhao, Xiangpeng Yang, Junfei Ma, Bin Ye, Xinglin Zhang","doi":"10.1080/03079457.2025.2514210","DOIUrl":"10.1080/03079457.2025.2514210","url":null,"abstract":"<p><strong>Research highlights: </strong>YbdO increases biofilm formation and acid resistance.YbdO upregulates the transcription levels of the biofilm-associated genes <i>bcsE</i>, <i>csgD</i>, <i>pgaA</i>, <i>wcaD</i>, <i>fimH</i>, and <i>flhD.</i>YbdO activates the expression of acid stress-associated genes <i>hdeA</i> and <i>yqgB.</i>YbdO contributes to improving the adaptability of APEC to environmental stresses.</p>","PeriodicalId":8788,"journal":{"name":"Avian Pathology","volume":" ","pages":"1-13"},"PeriodicalIF":2.5,"publicationDate":"2025-06-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144207503","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Fowl aviadenoviruses in Moroccan poultry: pathological characteristics and phylogenetic analysis of circulating fowl aviadenovirus strains from 2012 to 2024.","authors":"Ikram Ouchhour, Siham Fellahi, Abderrazak El Khantour, Sami Darkaoui, Mohammed Mouahid, Charifa Drissi Touzani, Samira Abghour, Faouzi Kichou","doi":"10.1080/03079457.2025.2509602","DOIUrl":"10.1080/03079457.2025.2509602","url":null,"abstract":"<p><strong>Research highlights: </strong>Increase in FAdV infections (IBH and GEUS) in Morocco over past decade.FAdV-positive cases were mainly found in broiler farms (79%).Identification of FAdV-11 and 8b serotypes for IBH, and FAdV-1, 8a and 8b for GEUS.</p>","PeriodicalId":8788,"journal":{"name":"Avian Pathology","volume":" ","pages":"1-10"},"PeriodicalIF":2.5,"publicationDate":"2025-06-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144109564","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}