Biocatalysis and agricultural biotechnology最新文献

{"title":"Quality and yield of potato seed tubers as influenced by plant growth promoting rizobacteria","authors":"Muhammad Raqib Rasul,&nbsp;Tavga Sulaiman Rashid","doi":"10.1016/j.bcab.2024.103440","DOIUrl":"10.1016/j.bcab.2024.103440","url":null,"abstract":"<div><div>Using chemical fertilizers in agriculture increases production and improves the quality of the product; however, their higher usage globally has brought forth damage to ecosystems. Using biofertilizers is a better strategy to reduce the use of chemical fertilizers and ultimately increase soil fertility. This study aimed to isolate, identify, and characterize bacteria from the soil rhizosphere of medicinal plants (<em>Rumex tuberosus</em> L. and <em>Verbascum</em> sp.) for <em>in vivo</em> screening. Nitrogen fixation, phosphate solubilization, HCN, ammonia levels, Lipase, protease, catalase and siderophore production biochemical tests were also conducted. The two isolates that gave positive results from the biochemical tests were chosen out of 25 for further experiments. Based on 16S rRNA sequencing analysis the isolated organisms were identified as <em>Alcaligenes faecalis</em> Go1 (Accession No. OP001725) and <em>Bacillus subtilis</em> T11 (Accession No. OP218376). The compound fertilizer NPK was used as the positive control for field experiments, while selected stains were individually and in-combination were tested on potato crops as inoculum, over two successive cropping seasons. Plant height, number of tubers per plant, chlorophyll content, and tuber weight all increased for both isolated bacterial strains. The quality of the potato tubers was checked through visual observation for the presence or absence of disease symptoms. The treated tubers exhibited excellent quality, remaining free from any signs of disease, however, the control tubers showed infections with (<em>Streptomyces scabiei, Fusarium</em> sp<em>., F. solani</em> and <em>Erwinia amylovora</em>). The soil analyzed after harvesting both bacteria increased percentages of P, Ca²+, Mg²+, Na+, K+, SO4, total nitrogen content and total organic matter. The findings showed that the tested bacterial isolates could replace the use of chemical fertilizers in the production of potatoes.</div></div>","PeriodicalId":8774,"journal":{"name":"Biocatalysis and agricultural biotechnology","volume":"62 ","pages":"Article 103440"},"PeriodicalIF":3.4,"publicationDate":"2024-11-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142698645","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Anti-quorum sensing mediated anti-infective efficacy of pentadecanoic acid against Staphylococcus aureus infections through in vitro, and in silico analyses","authors":"Nachammai Kathiresan ,&nbsp;Prabu D. ,&nbsp;Harini Kasilingam ,&nbsp;Sangavi P. ,&nbsp;Veera ravi Arumugam ,&nbsp;Langeswaran Kulanthaivel","doi":"10.1016/j.bcab.2024.103442","DOIUrl":"10.1016/j.bcab.2024.103442","url":null,"abstract":"<div><div>Methicillin-resistant <em>Staphylococcus aureus (</em>MRSA) is a significant human pathogen that is recognized for its tendency to produce biofilms, which plays a role in the development of antibiotic resistance and chronic infections. Since quorum sensing (QS) systems and biofilm formation are essential to <em>S. aureus</em> pathogenicity, they are significant targets for therapeutic intervention. Pentadecanoic acid (PA) was identified in <em>Hydnocarpus wightianus</em> seed extract. It's odd-chain saturated fatty acid with numerous benefits for cardiovascular, immunological, and liver function. It was found to be non-cytotoxic at all concentrations tested, with dose-dependent, broad anti-inflammatory and antiproliferative properties. PA showed concentration-dependent antibacterial action and its sub-inhibitory doses significantly decreased biofilm formation in all <em>S. aureus</em> strains. In addition, PA substantially lowered the formation of extracellular polymeric substance (EPS), protease activity, microbial adhesion, and motility, demonstrating its capacity to reduce bacterial pathogenicity. Microscopic examination revealed that the PA-treated cells had reduced biofilm development. The production of the virulence factor staphyloxanthin by <em>S. aureus</em> strains were substantially reduced in the presence of PA. Strong binding affinities of PA were found by molecular docking experiments to important target proteins associated with biofilm and QS, such as collagen adhesin (cna; PDB ID-1AMX), AgrA (PDB ID-4G4K), AgrC (PDB ID-4BXI), SarA (PDB ID-2FNP), and dehydrosqualene synthase (CrTM; PDB ID-2ZCO). The stability of PA with the <em>S. aureus</em> protein complex was further validated by molecular dynamics simulations. PA has the potential to be an efficient anti-virulence drug against <em>S. aureus</em> infections, providing a possible route for alternative therapies.</div></div>","PeriodicalId":8774,"journal":{"name":"Biocatalysis and agricultural biotechnology","volume":"62 ","pages":"Article 103442"},"PeriodicalIF":3.4,"publicationDate":"2024-11-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142698646","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Unveiling the chemical profile, anti-proliferative, pro-apoptotic and anti-migratory effect of Indigofera linifolia in liver and breast cancer cells","authors":"Irum Naz ,&nbsp;Muhammad Rashid Khan ,&nbsp;Saima Ali ,&nbsp;Riffat Batool","doi":"10.1016/j.bcab.2024.103441","DOIUrl":"10.1016/j.bcab.2024.103441","url":null,"abstract":"<div><div>Chemotherapeutic medications have a crucial role in treating various types of cancer. Nevertheless, the emergence of resistance in cancer cells and the detrimental effects on healthy cells emphasize the necessity for tailored therapies that selectively eradicate cancer cells. <em>Indigofera linifolia</em> has been extensively utilized for the management of several medical conditions, such as inflammation, cancer and febrile eruptions. This study's primary goal is to clarify the molecular mechanism of action of the methanol extract from <em>Indigofera linifolia</em> (ILM) and investigate any potential anticancer effects. Initially, we conducted MTT and flow cytometry analyses to evaluate cellular proliferation, apoptosis, and cell cycle arrest. Subsequently, we examined cell metastasis and protein markers using transwell migration, matrigel invasion assays, and western blotting techniques. The use of ILM led to a significant decrease in cell growth, an upsurge in programmed cell death, and a prevention of the spread of cancer cells in HCCLM3 and MDA-MB-231 cell lines. The molecular mechanism underlying the observed effects of ILM involves an increase in the levels of cleaved-PARP, cleaved-caspases (−3/-7/-8/-9), and proapoptotic proteins (Bax, Bak, and Bid), while decreased the level of protein that help cells divide (Cyclin D1/E), stop cells from dying (Bcl-xL, Bcl-2, XIAP, and Survivin), and proteins that help cells spread (MMP-2/-9). In addition, ILM affect the JAK/STAT3 signaling pathway in MDA-MB-231 cells, while triggers the JNK/MAPK pathway in HCCLM3 cells. Our study has provided additional evidence supporting the effectiveness of inhibiting STAT3 using the stattic inhibitor and JNK using the JNK inhibitor in reversing apoptosis induced by ILM in breast and liver cancer cells, respectively. Overall, our findings indicate that ILM possesses potential anticancer properties through modulation of several signaling pathways and found it a viable therapeutic option for cancer interventions.</div></div>","PeriodicalId":8774,"journal":{"name":"Biocatalysis and agricultural biotechnology","volume":"62 ","pages":"Article 103441"},"PeriodicalIF":3.4,"publicationDate":"2024-11-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142724169","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Harmonizing traditional and biotechnological approaches to engineer crop microbiomes: Enhancing resilience optimization","authors":"Muhammad Siddique Afridi ,&nbsp;Abdul salam ,&nbsp;Sher Ali ,&nbsp;Sumaira ,&nbsp;Willian César Terra ,&nbsp;Baber Ali ,&nbsp;Muhammad Atif Muneer ,&nbsp;Gustavo Santoyo","doi":"10.1016/j.bcab.2024.103433","DOIUrl":"10.1016/j.bcab.2024.103433","url":null,"abstract":"<div><div>Plants are constantly confronted with both abiotic and biotic stresses, significantly affecting plant growth, development, and ultimately reducing crop yield. These complex and dynamic stress factors constitute a significant challenge to global food security. Harnessing plant-associated microbiomes represents a key strategy for enhancing agricultural sustainability. In the current era, the field of plant microbiome engineering has acquired significant attention and holds vast potential to revolutionize novel agricultural management practices. Yet, many studies have primarily focused on addressing individual stressors, leaving the intricate interactions largely unexplored. Therefore, this work inquires into the classical and biotechnological and/or ¨omic¨ techniques to engineer plant microbiomes to overcome multiple stressors. Traditional methods such as soil amendments, selective substrates and organic agricultural practices for plant microbiome engineering, are evaluated. Other more direct and advanced multi-omics approaches, such as computational and synthetic biology, host genome manipulation, microbiome breeding and microbiome transplantation, are discussed. The combined effects of pathogen infections and abiotic stresses, with particular emphasis on drought stress, are also reviewed. In addition, the imperative role of plant-growth-promoting microorganisms (PGPM) as part of the resilient plant microbiome is also highlighted. Lastly, this work sheds light on the interplay between different organic agricultural and high-throughput advanced strategies, with the final goal of reshaping the plant microbiome and pave the way for sustainable agricultural practices.</div></div>","PeriodicalId":8774,"journal":{"name":"Biocatalysis and agricultural biotechnology","volume":"62 ","pages":"Article 103433"},"PeriodicalIF":3.4,"publicationDate":"2024-11-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142724171","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Modulations in Physiological and Biochemical attributes of Citrus Limon by selenium nanoparticles (SeNPs) under salinity stress","authors":"Hummera Nawaz ,&nbsp;Khawaja Shafique Ahmad ,&nbsp;Iqra Aslam ,&nbsp;Athar Mahmood ,&nbsp;Ansar Mehmood ,&nbsp;Ameer Khan ,&nbsp;Muhammad Jamil ,&nbsp;Amina Ameer ,&nbsp;Muhammad Faraz Khan ,&nbsp;Sajjad Hussain","doi":"10.1016/j.bcab.2024.103438","DOIUrl":"10.1016/j.bcab.2024.103438","url":null,"abstract":"<div><div>Salinity is recognized as a significant abiotic stressor that impairs crop growth and productivity. Elevated - soil and irrigation water salinity poses substantial ecological challenges for agriculture, particularly in semiarid and arid regions. High sodium (Na⁺) concentrations induce osmotic stress, leading to water deficits within plant cells. However, using nanoparticles can mitigate salt stress and enhance plant growth. This study investigates the effects of selenium nanoparticles on the physiobiochemical characteristics of <em>Citrus limon</em> L. seedlings under salt stress. Selenium nanoparticles act as both reducing and capping agents. Six-month-old lemon seedlings were subjected to varying salinity levels (100 mM and 200 mM NaCl) and treated with foliar applications of selenium nanoparticles at - 25 mg/L and 50 mg/L concentration. Most of the nanostructures were observed in the size range of 20–40 nm and anisotropic and irregular in shape. The results indicated that 200 mM NaCl significantly reduced the morphological and physio-biochemical parameters of the seedlings. However, a 50 mg/L concentration of SeNPs notably improved fresh and dry weights of roots and shoots and increased chlorophyll content. Biochemical attributes such as SOD, POD, CAT, APX, TSS, TFA, Proline, H₂O₂, and MDA were elevated under 200 mM NaCl, while NPK levels decreased. A concentration of 50 mg/L SeNPs was identified as optimal for enhancing the morphological and physiobiochemical parameters of <em>C</em>. <em>limon</em> seedlings under salt stress.</div></div>","PeriodicalId":8774,"journal":{"name":"Biocatalysis and agricultural biotechnology","volume":"62 ","pages":"Article 103438"},"PeriodicalIF":3.4,"publicationDate":"2024-11-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142698644","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Gluten proteins: A comprehensive review","authors":"Mohan Das ,&nbsp;Sophia Ofosuhemaa Duodu ,&nbsp;Sayantan Santra,&nbsp;Siddu Lalsangi,&nbsp;Rintu Banerjee","doi":"10.1016/j.bcab.2024.103437","DOIUrl":"10.1016/j.bcab.2024.103437","url":null,"abstract":"<div><div>This study explores the intricate relationship between gluten proteins, their adversaries as a food ingredient, their applications and their impact on individuals with various gluten-related sensitivities. It also delves into the multifaceted impacts of gluten, ranging from molecular mechanisms to socioeconomic effects. Ongoing research explores HLA-DQ restricted CD4⁺ T-cell roles in gluten-related disorders, revealing the dynamic nature of T-cell responses as the disorder progresses. A specific gluten-derived protein fragment, the 33-mer deamidated gliadin peptide (DGP), has been found to form oligomeric structures that can damage the gut epithelial cells, allowing harmful substances to enter the bloodstream and trigger inflammation and autoimmunity in susceptible individuals. Promising treatments include the transglutaminase 2 inhibitor ZED 1227, which has been shown to prevent intestinal damage and restore nutrient absorption in patients with gluten sensitivity. The economic burden of gluten-related disorders is highlighted to include direct and indirect costs, such as healthcare services, medical management, reduced work productivity, and missed educational opportunities. The gluten-free product market is also evaluated to have seen substantial growth due to the rising prevalence of gluten-related disorders and perceived health benefits. However, higher prices of gluten-free products pose financial challenges, particularly for lower-income groups. Additionally, the production of gluten-free products has environmental impacts that require a prompt need for sustainable sourcing and production practices. Therefore, as the demand for gluten-free products rises, this literature emphasizes the need for further research and innovation to navigate the intricate dynamics between gluten proteins and the ubiquitous processed food market, while envisioning a future with therapeutic innovations that may eliminate the necessity of complete gluten-free lifestyle, emphasizing the need for a balance between economic growth and health.</div></div>","PeriodicalId":8774,"journal":{"name":"Biocatalysis and agricultural biotechnology","volume":"62 ","pages":"Article 103437"},"PeriodicalIF":3.4,"publicationDate":"2024-11-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142724172","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Sustainable production of graphene using biomass waste as a precursor: Environmental and economic implications","authors":"Santhanalakshmi Nagendran ,&nbsp;Mohanraj Kumar ,&nbsp;Natarajan Prakash ,&nbsp;Ching-Lung Chen ,&nbsp;Melvin S. Samuel ,&nbsp;Ethiraj Selvarajan ,&nbsp;Jih-Hsing Chang","doi":"10.1016/j.bcab.2024.103434","DOIUrl":"10.1016/j.bcab.2024.103434","url":null,"abstract":"<div><div>This review examines the novel application of graphene derived from biomass in wastewater treatment. This study explores the synthesis methods and structural characteristics of graphene produced from biomass sources by examining the complex mechanisms involved in its production and properties. This study also illuminates the potential of using graphene derived from biomass as a catalyst for improving wastewater treatment technologies. The main objective is to clarify the exceptional effectiveness of graphene derived from biomass and its crucial role in promoting a more sustainable and healthier environment in the process of treating wastewater. This emphasizes its ability to adsorb, catalyze, and remove pollutants. The review explores the wide range of uses of this innovative material in tackling different pollutants in wastewater, highlighting its capacity as a sustainable and efficient method for environmental cleansing.</div></div>","PeriodicalId":8774,"journal":{"name":"Biocatalysis and agricultural biotechnology","volume":"62 ","pages":"Article 103434"},"PeriodicalIF":3.4,"publicationDate":"2024-11-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142659563","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Lignin-chitosan-based bioplastics from oil palm empty fruit bunches for seed coating","authors":"Erika Ayu Agustiany ,&nbsp;Deded Sarip Nawawi ,&nbsp;Antonio Di Martino ,&nbsp;Fahriya Puspita Sari ,&nbsp;Widya Fatriasari","doi":"10.1016/j.bcab.2024.103435","DOIUrl":"10.1016/j.bcab.2024.103435","url":null,"abstract":"<div><div>Lignin is a hydrophilic-hydrophobic biopolymer known for its antioxidant activity, which could make it a suitable coating material. In this research, a bioplastic based on the combination of alkali lignin from oil palm empty fruit bunches and chitosan was developed for seed coating via a dipping method. Chili seeds were used as a model in this study. The bioplastic was prepared via a modified solvent casting method at lignin:chitosan:glycerol weight ratio of 0.25:1.0:0.2. For the isolated lignin, the antioxidant activity, total phenolic content, methoxyl content, and equivalent weight were measured; for the bioplastic lignin, contact angle, swelling, antioxidant activity, mechanical properties and biodegradability were assessed. The presence of the coating was observed by Cryo-EM while the suitability of lignin-chitosan bioplastics for seed coating was evaluated by the germination rate, root length, height, and dry weight of the sprouts. The results showed that isolated lignin enhances the antioxidant activity of the lignin-chitosan liquid bioplastic by up to 84%. The addition of isolated lignin increased the contact angle and reduced the swelling rate of the bioplastics. The presence of lignin increases the tensile strength and elastic module in the biofilm. The microscopical investigation demonstrated the presence of the coating and no alteration in the seed surface morphology under the coating layer. The application of chitosan-lignin-based bioplastics maintain the quality of the seed during its shelf life. The germination rate of the coated chili seeds increased by up to 100% after one week of storage and 40–80% after five weeks of storage.</div></div>","PeriodicalId":8774,"journal":{"name":"Biocatalysis and agricultural biotechnology","volume":"62 ","pages":"Article 103435"},"PeriodicalIF":3.4,"publicationDate":"2024-11-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142659564","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Sustainable management of rice by-products: Environmental challenges, industrial applications, and circular bio-economy innovations","authors":"Ajay Kamboj ,&nbsp;Pardeep Kumar Sadh ,&nbsp;Prince Chawla ,&nbsp;Baljeet Singh Saharan ,&nbsp;Chandra Shekhar Seth ,&nbsp;Kandi Sridhar ,&nbsp;Joginder Singh Duhan ,&nbsp;Minaxi Sharma","doi":"10.1016/j.bcab.2024.103430","DOIUrl":"10.1016/j.bcab.2024.103430","url":null,"abstract":"<div><div>The agricultural sector plays an essential role in both human and economic growth, offering sustenance, employment, income, raw materials, technological progress, and sustainability. The growing awareness of the necessity to enhance agricultural production is gaining attention, primarily driven by the imperative to adequately nourish the continuously expanding global population. Diverse agricultural practices are causing harmful environmental consequences, posing a significant risk to ecological stability through issues such as soil degradation, water pollution, habitat loss, and biodiversity decline. Timely and effective agricultural waste management has become essential for preventing adverse environmental and health impacts. Biomass from rice crop harvesting and processing has been found in abundance around the world. Because of the abundance of this biomass in nature, researchers are harnessing it for various objectives, including global energy requirements, while supporting environmental sustainability. Due to this rationale, within the frameworks of emerging sustainable and circular models, the prioritization of agricultural waste valorization has gained prominence as a pivotal strategy aimed at advancing sustainable management and circular economy. This review mainly emphasizes on the rice bio-waste, its environmental and health-related issues, policies to control stubble burning, reduce pollution in the air, and sustainable management of the bio-waste into wealth using different approaches worldwide. We also investigated the potential contribution of rice-by-products wastes to bioenergy production (bioethanol, biogas, and biofuel), enzymes, nanoparticles, construction materials, animal husbandry, bioplastics, and other value-added products. We recommend that proper management of rice by-products may produce innovative bio-ingredients and biodegradable materials, and enhance green growth and a circular bioeconomy.</div></div>","PeriodicalId":8774,"journal":{"name":"Biocatalysis and agricultural biotechnology","volume":"62 ","pages":"Article 103430"},"PeriodicalIF":3.4,"publicationDate":"2024-11-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142659562","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Entomopathogenic microorganisms as biocontrol agents for agricultural sustainability","authors":"Preety Tomar ,&nbsp;Ajar Nath Yadav","doi":"10.1016/j.bcab.2024.103431","DOIUrl":"10.1016/j.bcab.2024.103431","url":null,"abstract":"<div><div>The implementation of effective resources in agricultural practices with minimal effects on the ecosystem is the foundation of agro-environmental sustainability. Indeed, insect pests are the key factors causing crop losses. Over the past 50 years, a variety of agrochemicals have been used to combat crop losses brought on by insect pests. However, greater awareness of the risks associated with chemical pesticides, as well as other insect resistance and revival issues, makes the use of alternative pest management methods necessary. The use of entomopathogens such as bacteria, fungi, viruses, and nematodes in biological control methods provides an excellent substitute that is effective against a variety of insect pests and pathogens. Entomopathogenic microorganisms are safe, affordable, and simple to implement as biocontrol agaents for pest management. Entomopathogens have a lot of potential for suppressing pest populations due to their astonishing qualities. Among the entomopathogens, bacteria are host-specific, fungi are more widely distributed, and other viruses and nematodes possess specific killing mechanisms. All these entomopathogens greatly affect both terrestrial insect pests and soil-dwelling insect pests. These virulent pathogens kill target insect pests by penetrating through natural apertures, ingestions, and sometimes through integuments. Application of entomopathogens reduce pesticide use, enhance environmental health, maintain productivity, and protect natural resources. Furthermore, investigations are still being conducted to find other potential elements, particularly looking into potential entomopathogens. To address the current problems, knowledge about their identification, mechanism of action, applications, bioformulation development, and commercialization is therefore required. The present review provides insight by revealing the biocontrol potential of entomopathogens for sustainable pest management.</div></div>","PeriodicalId":8774,"journal":{"name":"Biocatalysis and agricultural biotechnology","volume":"62 ","pages":"Article 103431"},"PeriodicalIF":3.4,"publicationDate":"2024-11-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142659063","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}