Biocatalysis and agricultural biotechnology最新文献

{"title":"Enhanced lipase production and characterization from Aeromonas media VBC8: Applications in biodegradation of lubricating oil waste","authors":"Ramalingam Kowsalya ,&nbsp;Karunakaran Saravanan ,&nbsp;Kandasamy Selvam ,&nbsp;Balakrishnan Senthilkumar ,&nbsp;Duraisamy Senbagam","doi":"10.1016/j.bcab.2024.103423","DOIUrl":"10.1016/j.bcab.2024.103423","url":null,"abstract":"<div><div>This study aimed to explore the potential of a novel indigenous strain for the improved production of lipase from castor oil-contaminated soil. Among the various isolates, <em>Aeromonas media</em> VBC8 was found to be the most effective for lipase production. The effect of different inducer oils (olive, peanut, soybean, rice bran, sunflower, coconut, sesame, and fish liver oil) on the biomass of <em>A. media</em> VBC8 and its lipase activity was determined. Among the various oils assessed, fish liver oil exhibited highest lipase activity, with 89 U/mL with 9.1 g/L of biomass. Furthermore, Box-Behnken Design was used to optimize the cultural conditions resulting in an enhanced lipase activity of 1156 U/mL. The lipase was purified through ammonium salt (60 w/v %) precipitation, desalting and ion exchange column, achieving a yield of 16 % and specific activity of 98.4 U/mL. The purified lipase remained active over a wide range of pH 4.0–11.0 and temperature of 10–80 °C with maximum activity at pH 8.0 and 40 °C. SDS-PAGE analysis revealed the lipase's molecular weight to be 94 kDa. The study also evaluated the role of crude and purified lipase in the biodegradability of lubricating oil waste, achieving a maximum fatty acid conversion of 39 and 76 %, respectively, after 7 h incubation at room temperature.</div></div>","PeriodicalId":8774,"journal":{"name":"Biocatalysis and agricultural biotechnology","volume":"62 ","pages":"Article 103423"},"PeriodicalIF":3.4,"publicationDate":"2024-10-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142586187","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Optimization of shrimp and crab shell as bio-flocculant for Chlorella pyrenoidosa harvesting using response surface methodology","authors":"Hadiyanto Hadiyanto ,&nbsp;Wahyu Diski Pratama ,&nbsp;Rifqi Ahmad Baihaqi ,&nbsp;Wahyu Zuli Pratiwi ,&nbsp;Jihan Cinantya Prajwalita ,&nbsp;Oktaviani Wiradhianty","doi":"10.1016/j.bcab.2024.103422","DOIUrl":"10.1016/j.bcab.2024.103422","url":null,"abstract":"<div><div>The use of bio-flocculants in flocculation processes offers a feasible approach for separating solid and liquid phases, with a particular focus on microalgae harvesting. Critical parameters such as the dose of bio-flocculant, pH level, and dose of cationic inducer significantly impact the success of microalgae harvesting. This study aims to examine the efficacy of chitosan derived from shrimp shells and crab shells as bio-flocculants in microalgae harvesting, specifically <em>Chlorella pyrenoidosa</em>. Central Composite Design (CCD) and Response Surface Methodology (RSM) were employed in this study to attain optimal flocculation conditions, characterized by high flocculation efficiency and short settling time. The optimal harvesting condition using chitosan derived from shrimp shells was achieved at 0.499 g/L of bio-flocculant, pH 9.09, and 0.172 g/L of cationic inducer with 92.58% efficiency and 133.49 s settling time. Meanwhile, The optimal harvesting condition with chitosan derived from crab shells was achieved at 0.434 g/L of bio-flocculant, pH 8.96, and 0.168 g/L of cationic inducer. This resulted in an efficiency of 93.72% and a settling time of 117 s. Based on this fact, the potential of shrimp shells and crab shells as bio-flocculants for <em>Chlorella pyrenoidosa</em> harvesting is evident. Furthermore, the efficacy of flocculation and settling time are significantly influenced by variables such as the concentration of cationic inducers, the levels of bio-flocculants, and pH.</div></div>","PeriodicalId":8774,"journal":{"name":"Biocatalysis and agricultural biotechnology","volume":"62 ","pages":"Article 103422"},"PeriodicalIF":3.4,"publicationDate":"2024-10-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142573140","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Microbial synthesis of zinc oxide nanoparticles and their potential biological application as an antimicrobial and anticancer agent","authors":"Rajendiran Ishwarya ,&nbsp;Rajapandian Rajaganesh ,&nbsp;Mani Geetha ,&nbsp;Giriraj Kalaiarasi ,&nbsp;Narayanasamy Arul ,&nbsp;Jayakumar Tharani ,&nbsp;Krishnamoorthy Kavithaa ,&nbsp;Dayalan Sangeetha","doi":"10.1016/j.bcab.2024.103417","DOIUrl":"10.1016/j.bcab.2024.103417","url":null,"abstract":"<div><div>Zinc oxide nanoparticles (ZnO-NPs) are a type of metal oxide nanomaterial, recognized as a valuable and adaptable inorganic compound owing to its distinctive physical and chemical properties. Nanosized ZnO particles exhibit substantial antibacterial properties attributable to their diminutive size, which can activate various bactericidal mechanisms within the bacterial cell, including interactions with the bacterial surface or core, the generation of reactive oxygen species (ROS), the release of Zn2+, and potential endocytosis by cells. ZnO NPs nanoparticles were extracellularly produced using pigment extracts from the PP6 strain. Agar well screening indicated that PP6 secondary metabolites possess antibacterial properties. UV–Vis spectroscopy was used to analyze the external growth of nanoparticles. Scanning Electron Microcopy (SEM), Fourier Transform Infrared Spectroscopy (FTIR), and X-ray diffraction (XRD) techniques were employed to analyze the shape, stability, crystalline structure, and coating of strain PP6 ZnO NPs. The PP6 ZnO NPs demonstrated an antibiofilm impact on the bacterial pathogens tested, which was dependent on the dosage. Elevated levels of lipid peroxidation (LPO) and reduced antioxidant activity are indicative of apoptosis in cancer cells. The synthesized ZnO NPs nanoparticles were assessed for their anticancer properties by performing the MTT assay on HT-29 human colorectal adenocarcinoma cells. ZnO NPs nanoparticles exposed to HT-29 cells the viability was reduced significantly in proportion to the concentration of nanoparticles. Additional comprehensive study will be needed to fully understand their mechanism.</div></div>","PeriodicalId":8774,"journal":{"name":"Biocatalysis and agricultural biotechnology","volume":"62 ","pages":"Article 103417"},"PeriodicalIF":3.4,"publicationDate":"2024-10-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142578495","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Comparison of the anti-inflammatory effects of carotenoids-rich product from microalgal mass-cultured between natural seawater and magma seawater","authors":"Jayeon Cheon ,&nbsp;Eun-A Kim ,&nbsp;Nalae Kang ,&nbsp;Taeho Kim ,&nbsp;Lei Wang ,&nbsp;Soo-Jin Heo ,&nbsp;Seon-Heui Cha","doi":"10.1016/j.bcab.2024.103420","DOIUrl":"10.1016/j.bcab.2024.103420","url":null,"abstract":"<div><div>Microalgae can be mass-produced in a short period of time and are rich in high value-added product such as carotenoids, thereby it is widely used in a variety industrial field. However, the production cost expensed a lot due to high price of culture ingredient, vitamins. Additionally, &gt;80% of synthetic carotenoids are used in industrial field, and their cost is also highly expensed. Therefore, in this study, a microalga, <em>Tetraselmis</em> sp. was mass-cultured using natural seawater (NS) and magma seawater (MS) as vitamins. As a result of comparing the general composition between the extracts cultured in two culture media, crude carbohydrate and crude lipid contents were 2.68% and 4.38% higher, respectively, while crude protein content was 4.1% lower in the MS culture media. The extraction yield was 8.6% higher in the MS than the NS culture media. Also, lutein and zeaxanthin were predominantly presented in the species and detected in the microalgal extract cultured in MS was 2- and 8-folds higher, respectively, than in NS. Consequently, the carotenoids-rich extracts cultured with two seawaters were exhibited prominent anti-inflammatory effects by suppressing nitric oxide (NO) overproduction and pro-inflammatory mediator such as tumor necrosis factor (TNF)-α, interleukin (IL)-1β, IL-6, inducible nitric oxide synthase (iNOS), and cyclooxygenase (COX)-2 expression through MAPKSs and NF-κB pathway. Interestingly, extract of microalgal cultured in MS showed a more efficient anti-inflammatory effect. These results suggest that the value of MS in increasing the carotenoids contents with beneficial effects in mass cultivation of microalgae.</div></div>","PeriodicalId":8774,"journal":{"name":"Biocatalysis and agricultural biotechnology","volume":"62 ","pages":"Article 103420"},"PeriodicalIF":3.4,"publicationDate":"2024-10-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142594034","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Unraveling the potential of cyanobacteria as food and investigating its production and nutritional properties","authors":"Sreemanti Banerjee ,&nbsp;Rupanjali Lahiri ,&nbsp;Avik Kumar Choudhury ,&nbsp;Anwesha Mondal ,&nbsp;Jung-Wan Kim ,&nbsp;Davoodbasha MubarakAli ,&nbsp;Gour Gopal Satpati","doi":"10.1016/j.bcab.2024.103421","DOIUrl":"10.1016/j.bcab.2024.103421","url":null,"abstract":"<div><div>Producing energy and food sustainably is essential in order to be eco-friendly, especially with the increasing global population and the depletion of natural energy sources. Cultivating cyanobacteria has gained worldwide interest because of their efficient use of CO₂ and solar energy. Cyanobacteria have the potential to serve as a viable substitute for food as they do not need fertile land for growth, have minimal nutritional requirements for maximum biomass production, and offer high nutritional value. <em>Arthrospira</em> (<em>Spirulina</em>) and <em>Nostoc</em> are often referred to as “single cell protein” due to their high protein content and are widely marketed as functional food globally. The carbohydrate levels in <em>Nostoc commune</em> and <em>Scytonema bohneri</em> surpass those in <em>Arthrospira</em>. Unlike other algal groups that have monounsaturated and saturated fatty acids, cyanobacteria boast high levels of polyunsaturated fatty acids (PUFA), which are advantageous for health and serve as an intriguing ingredient in cosmetics. <em>Arthrospira</em> is simple to produce on a large scale and has garnered interest in a wide range of uses including food, medicine, aquaculture, nano-technology, dyes, agriculture, cosmetics, and feed. Recent review highlighted the positive nutritional properties of <em>Arthrospira</em>, <em>Nostoc</em> and <em>Aphanizomenon</em>. The biochemical composition of <em>Arthrospira</em> and its potential as a food source were thoroughly discussed. In addition, this study provided a comprehensive study of the single cell protein, elucidating the production process and its limitations and rules and regulations governing the use of single cell proteins. The potential of cyanobacteria as a sustainable food source for future generations was confidently argued.</div></div>","PeriodicalId":8774,"journal":{"name":"Biocatalysis and agricultural biotechnology","volume":"62 ","pages":"Article 103421"},"PeriodicalIF":3.4,"publicationDate":"2024-10-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142553575","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Overexpression of Gossypium arboreum 3-ketoacyl-CoA synthase 6 (GaKCS6) gene enhanced leaf epicuticle wax in Gossypium hirsutum L. and improved tolerance against whitefly","authors":"Muhammad Umair Majid,&nbsp;Rabiah Ashraf,&nbsp;Basit Jabbar,&nbsp;Usman Arif,&nbsp;Fatima Batool,&nbsp;Sameera Hassan,&nbsp;Bushra Rashid","doi":"10.1016/j.bcab.2024.103418","DOIUrl":"10.1016/j.bcab.2024.103418","url":null,"abstract":"<div><div>Cotton Leaf Curl Virus (CLCuV) is a significant threat to cotton production, as it causes Cotton Leaf Curl Disease (CLCuD). Whitefly serves as a vector for the transmission of this virus. It can be controlled by developing barriers against whitefly infestation. The leaf epicuticle wax acts as a protective barrier against whitefly attacks. Research into wax biosynthesis and the fatty acid elongation pathway has highlighted the role of the 3-ketoacyl-CoA synthase (<em>KCS</em>) gene family in producing very-long-chain fatty acids (VLCFAs) in plants. The 3-ketoacyl-CoA synthase 6 (<em>GaKCS6</em>) gene, isolated from the CLCuV-resistant FDH-170 variety of <em>Gossypium arboreum</em>, was cloned under the control of the <em>Ca</em>MV35S constitutive promoter and transformed into the CLCuV-susceptible <em>Gossypium hirsutum</em> variety CKC-3 resulting in significantly higher leaf epicuticle wax deposition. Overexpression of <em>GaKCS6</em> in the transgenic cotton plants was confirmed through quantitative real-time PCR. The transgenic plants not only exhibited average growth but also showed improvements in agronomic traits. Scanning Electron Microscope (SEM) analysis further validated the enhanced leaf epicuticle wax deposition in transgenic plants compared to non-transgenic (control). A free-choice bioassay against whiteflies demonstrated that the transgenic plants remained free of viral infection, as confirmed by real-time PCR. These findings indicate that increased leaf epicuticle wax deposition in transgenic cotton effectively prevents whitefly attacks and the transmission of CLCuV. It suggests that the <em>GaKCS6</em> gene plays a crucial role in producing leaf epicuticle wax through the VLCFAs biosynthesis pathway.</div></div>","PeriodicalId":8774,"journal":{"name":"Biocatalysis and agricultural biotechnology","volume":"62 ","pages":"Article 103418"},"PeriodicalIF":3.4,"publicationDate":"2024-10-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142553478","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A comprehensive review on polyhydroxyalkanoate: Genetic engineering to enhance production and feedstocks assimilation as green alternative for Petrochemical plastics","authors":"Isha Bodhe ,&nbsp;Alka Mehta ,&nbsp;G. Velvizhi","doi":"10.1016/j.bcab.2024.103419","DOIUrl":"10.1016/j.bcab.2024.103419","url":null,"abstract":"<div><div>Microbial polyhydroxyalkanoates (PHA) are promising biopolymers due to their excellent biocompatibility and biodegradability having the potential to be sustainable plastic alternatives for fossil-derived polymers. Carbon flow and energy metabolism divert towards central carbon metabolism, which limits PHA assimilation. Hence genetic engineering strategies target the strains specifically for enhanced PHA synthesis by up-regulating and knocking down operons, thus regulating the biochemical pathway. This review provides an in-depth understanding of genetics in PHA accumulation and briefly discusses its structural properties. <em>C</em><em>upriavidus</em> <em>necator</em> is the pioneer bacteria for PHA production; others, such as <em>Pseudomonas</em> sp. and <em>Bacillus</em> sp., avail themselves for the robust PHA production capabilities of genetically modified organisms. Genetic engineering techniques used for PHA production have been detailed and discussed like CRISPR based systems have also served as efficient genome editing tools to improve the efficiency of metabolic modification. The most promising methods to boost the yield were highlighted, along with the metabolic paradigms of PHA-producing bacteria and a summary of the range of inexpensive carbon substrates that are used. It also coveres how metabolic modification can support microbial cell factories that use various fermentation techniques and co-production systems to produce PHA using modified strains. Nevertheless, the high cost of production preventing PHA from being commercialised could be by-passed via., genetically modified strains or enriched Mixed Microbial Culture (MMC) as a cheaper option along with the solvent-free downstream processes appear to be a promising bioroute to lower PHA costs.</div></div>","PeriodicalId":8774,"journal":{"name":"Biocatalysis and agricultural biotechnology","volume":"62 ","pages":"Article 103419"},"PeriodicalIF":3.4,"publicationDate":"2024-10-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142539904","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Biopriming of Solanum lycopersicum seeds with novel root endophytic bacterial consortium retrieved from halotolerant Sundarban mangroves to sustain growth and yield with salt resilience","authors":"Anwesha Chatterjee ,&nbsp;Proma Ghosh ,&nbsp;Murali Sharaff ,&nbsp;Prateek Madhab Bhattacharya ,&nbsp;Harshata Pal","doi":"10.1016/j.bcab.2024.103414","DOIUrl":"10.1016/j.bcab.2024.103414","url":null,"abstract":"<div><div>Mangroves are often found in coastal areas and tropical wetlands that can withstand high salinity. We hypothesized that endophytes that are harbouring in the roots of mangrove plants may improve the innate immunity of host plants to survive naturally in saline environment. Retrieving these endophytes and sequential characterization may function as a novel bio-effector for non-host food crops as well. We focused on the integrated approach towards formulating a novel bacterial consortium. Thirty-one bacterial endophytes isolated from the roots of mangrove plants were screened for plant growth promoting potential by inoculating our model crop (Tomato). Seven most promising isolates impacting plant growth were identified. <em>In-vitro</em> plant growth promoting characters were also analysed. The root colonization by the isolates was confirmed by Scanning Electron Microscopy (SEM). Among the screened isolates, four of them were found to be compatible with each other when grown together and were selected to formulate a novel biostimulant consortia. The consortia treated Tomato plants exhibited superior phenological characters. In the pot experiment, plant height of the treated plants was about ≈43 cm while the non-treated plants under salt stress could grow only up to a height of ≈26 cm. Similarly, a total fruit yield of ≈6.8 kg was observed in case of treated plants under salt stress whereas the non-treated plants under salt stress could only produce ≈4.7 kg of fruit. This study demonstrated that the beneficial bacteria inhabiting in mangrove roots can increase the potential of conferring salt tolerance to non-host crops, thereby contributing to sustainable agriculture.</div></div>","PeriodicalId":8774,"journal":{"name":"Biocatalysis and agricultural biotechnology","volume":"62 ","pages":"Article 103414"},"PeriodicalIF":3.4,"publicationDate":"2024-10-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142553479","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Accumulation of podophyllotoxin in the root culture of Hyptis suaveolens (L.) Poit: A potential natural lignan for clinically useful anticancer drugs","authors":"Sâmia Torres Silva ,&nbsp;Rafael Marlon Alves de Assis ,&nbsp;Adriane Duarte Coelho ,&nbsp;Simony Carvalho Mendonça ,&nbsp;Lurdeslaine Faria Texeira ,&nbsp;Suzan Kelly Vilela Bertolucci ,&nbsp;José Eduardo Brasil Pereira Pinto","doi":"10.1016/j.bcab.2024.103416","DOIUrl":"10.1016/j.bcab.2024.103416","url":null,"abstract":"<div><div>Podophyllotoxin (PTOX) is a natural antiviral, antirheumatic and anticancer molecule, but it is expensive to chemically synthesize. The present study aimed to evaluate growth and PTOX accumulation in root cultures of <em>Hyptis suaveolens</em> treated with different concentrations of auxins, vitamins and myo-inositol. Root cultures grown in liquid medium supplemented with different concentrations of indole-3-butyric acid (IBA), 1-naphthaleneacetic acid (NAA), vitamins and myo-inositol were used to measure biomass production and PTOX content. PTOX quantitation was performed via high-performance liquid chromatography with diode-array detection (HPLC-DAD) using a newly developed analytical method after successful validation. Root culture in MS medium supplemented with 1 mg L⁻¹ IBA +0.5 mg L⁻¹ NAA resulted in the highest root dry weight (248.76 mg) and the highest PTOX concentration in the roots (179.97 μg g⁻¹ root). The roots cultured in liquid MS medium supplemented with 1 mg L⁻¹ IBA +0.5 mg L⁻¹ NAA presented the greatest increase in root biomass and PTOX content. This adequate balance of vitamin and myo-inositol supplementation in liquid MS culture medium increased the root dry weight and PTOX content.</div></div>","PeriodicalId":8774,"journal":{"name":"Biocatalysis and agricultural biotechnology","volume":"62 ","pages":"Article 103416"},"PeriodicalIF":3.4,"publicationDate":"2024-10-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142528556","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Microalgae to remove pharmaceutical and personal care products (PPCPs) from wastewater","authors":"Madhumita Ravikumar ,&nbsp;Karrun Velmurugan ,&nbsp;Ashwini J. John ,&nbsp;Ethiraj Selvarajan","doi":"10.1016/j.bcab.2024.103415","DOIUrl":"10.1016/j.bcab.2024.103415","url":null,"abstract":"<div><div>Substances used for medicinal, cosmetic, hygiene, and health care objectives are included in the category of pharmaceuticals and personal care products (PPCPs). They are a major source of public concern because of their ubiquitous manufacturing, usage, and careless disposal of expired products into the environment. Many PPCPs, including antibiotics, analgesics, endocrine disruptors, and microbial/disinfecting agents, are commonly detected in freshwater systems, groundwater, and wastewater treatment effluents in amounts ranging from nanograms per liter to milligrams per milliliter. Additionally, these compounds frequently show persistence and accumulate in biological tissue, eventually finding their way into crops, vegetables, and drinking water supplies. Because many PPCPs are known to have the ability to upset ecosystems and/or provide health hazards, they are categorized as “emerging contaminants.” The research on the occurrence, fate, and possible health and environmental hazards related to PPCPs in both aquatic and terrestrial habitats is thoroughly reviewed in this work. It also covers reported cases of danger or health concerns in humans, although a full assessment may not be possible given the limitations of the data at hand. This review aims to provide a comprehensive and well-focused overview of the current understanding of bioremediation strategies for the removal of pharmaceuticals and personal care products (PPCPs), with an emphasis on the application of macroalgae, microalgae, and aquatic macrophytes. It examines the physicochemical properties of PPCPs and their potential risks to environmental and human health. Additionally, the review explores the potential and challenges associated with the broader application of biotechnologies employing algae and aquatic macrophytes. This includes research efforts to correlate the operational parameters of these biotechnologies with the primary mechanisms responsible for PPCP removal. In conclusion, algae and macrophytes present promising, eco-friendly solutions for wastewater treatment, significantly contributing to the mitigation of PPCP contamination.</div></div>","PeriodicalId":8774,"journal":{"name":"Biocatalysis and agricultural biotechnology","volume":"62 ","pages":"Article 103415"},"PeriodicalIF":3.4,"publicationDate":"2024-10-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142528557","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}