Biochemical Engineering Journal最新文献

{"title":"ZrO2/g-C3N4 heterojunction nanocomposites for enhanced photocatalytic degradation of organic pollutants and antibacterial activity","authors":"Shweta Vashisth,&nbsp;S.P. Nehra","doi":"10.1016/j.bej.2026.110085","DOIUrl":"10.1016/j.bej.2026.110085","url":null,"abstract":"<div><div>In the current study, zirconium oxide/graphitic carbon nitride (ZrO₂/g-C₃N₄) nanocomposites have been synthesized using <em>Murraya koenigii</em> leaf extract as an eco-friendly reducing and stabilizing agent. The properties of the ZrO₂/g-C₃N₄ nanocomposites were investigated by employing several analytical techniques such as X-ray diffraction (XRD), Fourier-transform infrared spectroscopy (FTIR), thermogravimetric analysis (TGA), X-ray photoelectron spectroscopy (XPS), high-resolution transmission electron microscopy (HRTEM), UV-Vis diffuse reflectance spectroscopy (UV-DRS), field emission scanning electron microscopy (FESEM), energy-dispersive X-ray analysis (EDX), and elemental mapping. The photocatalytic activity of the nanocomposites was evaluated through the use of ultraviolet-visible (UV-Vis) spectroscopy for the removal of the organic dyes, xylenol orange (XO) and malachite green (MG) dyes. Following a thorough analysis, it has been demonstrated that, in comparison to other samples, the ZrCN 2 nanocomposite showed significantly enhanced photocatalytic dye degradation activity for malachite green (94.31 %) and xylenol orange (59.28 %) dyes. To support the potential use of the synthesized nanomaterials against <em>Escherichia coli</em>, an antibacterial study has also been conducted. ZrCN 2 showed the highest antibacterial activity against <em>E. coli</em> compared to the other samples, with an 8-mm zone of inhibition and the lowest minimum inhibitory concentration (30 µg). The composite's recyclability test has been performed for up to five cycles, and its photodegradation results remained consistent. Moreover, a scavenger experiment was conducted to determine the major reactive oxygen species (ROS) involved in the photocatalytic mechanism. The outcomes of the present investigation offer important insights into the synthesis and characterization of ZrO₂/g-C₃N₄ nanocomposites that demonstrate enhanced photocatalytic dye degradation and antibacterial efficiency as compared to pure g-C₃N₄ and ZrO₂ nanoparticles.</div></div>","PeriodicalId":8766,"journal":{"name":"Biochemical Engineering Journal","volume":"228 ","pages":"Article 110085"},"PeriodicalIF":3.7,"publicationDate":"2026-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146035098","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Amelioration of mining-area soils with microbial induction of magnesium ammonium phosphate","authors":"Zhe Wang ,&nbsp;Wen-yan Zhang ,&nbsp;Jun-li Cheng ,&nbsp;Shu-hui Wei ,&nbsp;Hong-yuan Cui ,&nbsp;Wei-da Wang","doi":"10.1016/j.bej.2026.110075","DOIUrl":"10.1016/j.bej.2026.110075","url":null,"abstract":"<div><div>Large-scale mineral exploitation causes heavy metal pollution and nutrient depletion in mining-area soils, making heavy metal control and soil fertility improvement urgent. This study synthesized biological magnesium ammonium phosphate (bio-MAP) via microbially induced mineralization, characterized its microstructure, and conducted pot experiments with ryegrass and alfalfa under different bio-MAP additions to analyze effects on soil physicochemical properties, Pb²⁺/Cd²⁺ contents, and plant growth. X-ray diffraction (XRD), Fourier transform infrared spectroscopy (FTIR) and scanning electron microscopy (SEM) confirmed the precipitate was mainly struvite (MgNH₄PO₄·6H₂O) with a regular orthorhombic structure. Appropriate bio-MAP addition not only facilitated the formation of large soil aggregates and enhanced soil structural stability but also significantly promoted the growth of ryegrass and alfalfa. At the 30-day harvest, the total fresh weight of ryegrass reached 1.33 g in the P5 treatment (bio-MAP addition: 1000 mg/kg), while that of alfalfa reached 2.36 g in the P3 treatment (bio-MAP addition: 500 mg/kg). Compared with the control, the P1, P3, and P5 treatments reduced soil available Pb content by 7.16 %, 15.1 %, and 19.28 %, respectively, and soil available Cd content by 58.57 %, 62.31 %, and 65.1 %, respectively. Bio-MAP also increased soil sucrase activity and abundances of <em>Proteobacteria</em>, <em>Actinobacteria</em>, and <em>Bacillus</em>. This study provides a new method for mine soil amendment and heavy metal control, plus references for ecological restoration.</div></div>","PeriodicalId":8766,"journal":{"name":"Biochemical Engineering Journal","volume":"228 ","pages":"Article 110075"},"PeriodicalIF":3.7,"publicationDate":"2026-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145923131","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Transient heat and mass transfer in a wall-cooled packed-tray bioreactor for solid-state fermentation: An engineering framework for parameter estimation","authors":"Gerardo A. Gómez-Ramos ,&nbsp;Lilia A. Prado-Barragán ,&nbsp;Sergio Huerta-Ochoa ,&nbsp;Victor M. Rivera ,&nbsp;Ángeles García-Hernández ,&nbsp;Carlos O. Castillo-Araiza","doi":"10.1016/j.bej.2026.110071","DOIUrl":"10.1016/j.bej.2026.110071","url":null,"abstract":"<div><div>Solid-state fermentation (SSF) of agrifood byproducts (AFBP) offers a sustainable route for producing high-value biomolecules, yet its industrial adoption is constrained by limited understanding of transport phenomena in wall-cooled packed bioreactors. Despite their potential for large-scale SSF, reliable methods for describing heat and mass transfer remain scarce. Building on previous fluid-dynamic studies, this work characterizes intrinsic transport mechanisms in a bench-scale wall-cooled tray packed with AFBP as substrate. An engineering framework not previously applied to these systems, integrating abiotic experiments, fluid dynamics, and transient analysis, was applied to estimate the effective thermal conductivity (<span><math><msub><mrow><mi>k</mi></mrow><mrow><mi>eff</mi></mrow></msub></math></span>), wall heat transfer coefficient (<span><math><msub><mrow><mi>h</mi></mrow><mrow><mi>w</mi></mrow></msub></math></span>), and axial dispersion coefficient (<span><math><msub><mrow><mi>D</mi></mrow><mrow><mi>ax</mi></mrow></msub></math></span>). Experiments under conditions favorable to <em>Yarrowia lipolytica</em> 2.2ab (318.15 K, 60 % moisture on a dry-weight basis, and inlet specific airflow rates, <em>VkgM</em>, of 1.875–6.250 L.kg⁻¹.min⁻¹) yielded values of 0.565–4.34 W.m⁻¹ .K⁻¹ for <span><math><msub><mrow><mi>k</mi></mrow><mrow><mi>eff</mi></mrow></msub></math></span>, 0.865–25.9 W.m⁻².K⁻¹ for <span><math><msub><mrow><mi>h</mi></mrow><mrow><mi>w</mi></mrow></msub></math></span>, and 2.60 × 10⁻³ –5.30 × 10⁻³ m².s⁻¹ for <span><math><msub><mrow><mi>D</mi></mrow><mrow><mi>ax</mi></mrow></msub></math></span>. These results differ from previous SSF studies employing AFBP, highlighting the influence of reactor configuration, operating conditions, and parameter estimation approach. The proposed methodology provides a reliable framework for evaluating heat and mass transfer in SSF systems using AFBP as a substrate and establishes a foundation for predictive design and scale-up of packed bioreactors in biotechnological applications.</div></div>","PeriodicalId":8766,"journal":{"name":"Biochemical Engineering Journal","volume":"228 ","pages":"Article 110071"},"PeriodicalIF":3.7,"publicationDate":"2026-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145923132","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Competitive and synergistic effects of manganese-nitrogen co-doped sludge biochar on the chlortetracycline hydrochloride and Cu²⁺ from water","authors":"Xinhua Zhou,&nbsp;Zhihao Li,&nbsp;Ziqiang Ding,&nbsp;Lin Lu,&nbsp;Letong Wang","doi":"10.1016/j.bej.2026.110082","DOIUrl":"10.1016/j.bej.2026.110082","url":null,"abstract":"<div><div>Addressing the issue of simultaneous antibiotic and heavy metal contamination in effluent from intensive animal husbandry, this study used sewage sludge as the raw material. It employed co-doping modification with urea and manganese chloride to synthesize a sludge biochar composite (Mn-N-SBC) through pyrolysis for removing CTC and Cu^2 + from aquaculture effluent. Experimental results showed that in the single system, the Qemax values were 93.27 mg/g and 31.45 mg/g, respectively. In the binary system, the Qemax values were 94.89 mg/g and 30.76 mg/g, respectively. These findings indicate that competing interactions and synergistic effects coexist during the concurrent removal of CTC and Cu²⁺ by Mn-N-SBC. Microstructural analysis suggests that the competitive adsorption of CTC and Cu²⁺ on Mn-N-SBC mainly results from their competition for the same active sites. This enhanced adsorption can be attributed to electrostatic interactions, Cu²⁺ bridging effects, and interactions involving O/N functional groups within CTC molecules. Overall, this study clarifies the concurrent adsorption mechanism of Mn-N-SBC for CTC and Cu²⁺, offering both a strategy for sludge valorization and a template for designing multifunctional adsorbents to treat complex wastewater.</div></div>","PeriodicalId":8766,"journal":{"name":"Biochemical Engineering Journal","volume":"228 ","pages":"Article 110082"},"PeriodicalIF":3.7,"publicationDate":"2026-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145974087","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Sustainable valorization of rapeseed meal to bioactive and nutritional products via solid-state fermentation with protease-enhanced Streptomyces sp. SCUT-3","authors":"Zhen-Jie Dai ,&nbsp;Wen-Jing Feng ,&nbsp;Can Qin ,&nbsp;Hua-Hong Cai ,&nbsp;Jing-Yi Hu ,&nbsp;Zhi-Wei Li ,&nbsp;Ming-Shu Zhang ,&nbsp;Lei Wu ,&nbsp;Jun-Jin Deng ,&nbsp;Xiao-Chun Luo","doi":"10.1016/j.bej.2026.110086","DOIUrl":"10.1016/j.bej.2026.110086","url":null,"abstract":"<div><div>To meet the growing global demand for protein driven by population increases, converting agricultural by-products into edible protein is critical for sustainable food security. This study introduces a solid-state fermentation (SSF) platform utilizing protease-engineered <em>Streptomyces</em> sp. SCUT-3 for the valorization of rapeseed meal (RSM), the world’s second-largest oilseed residue. Optimized SSF parameters (substrate-liquid ratio 1:2 w/v, 2-day fermentation) achieved 82.2 % protein recovery rate, yielding 15.3 g free amino acids (FAAs) and 17.8 g soluble peptides (SPPs) (96 % &lt; 2000 Da) per 100 g RSM (40.28 g protein). Fermented RSM (FRSM) showed significant improvements: 86.5 % protein digestibility (a 2.6-fold enhancement), and a more enriched nutritional profile with 47.4 % essential amino acids in FAAs. Additionally, SSF effectively reduced anti-nutritional factors, removing 92 % glucosinolates and nearly 100 % phytic acid. Structural analysis revealed that FRSM’s fragmented, porous morphology facilitated improved nutrient absorption. A largemouth bass feeding trial demonstrated the practical benefits of FRSM, where a 10 % replacement in feed increased weight gain rate and feed intake compared to RSM-fed controls. This study provides a scalable and sustainable solution for the valorization of RSM, addressing both protein security and circular economy objectives.</div></div>","PeriodicalId":8766,"journal":{"name":"Biochemical Engineering Journal","volume":"228 ","pages":"Article 110086"},"PeriodicalIF":3.7,"publicationDate":"2026-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146035099","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Membrane transporter mining and enzyme engineering drive high-titer δ-tocotrienol production in Yarrowia lipolytica","authors":"Chenchen Xu ,&nbsp;Xinyu Jiao ,&nbsp;Quanlu Zhao ,&nbsp;Tianli Yuan ,&nbsp;Haoran Bi ,&nbsp;Kai Wang ,&nbsp;Tianwei Tan","doi":"10.1016/j.bej.2026.110079","DOIUrl":"10.1016/j.bej.2026.110079","url":null,"abstract":"<div><div>δ-Tocotrienol, a vitamin E bioactive isoform, possesses strong antioxidant and anticancer properties. However, its production is limited by its extremely low abundance in plants and the difficulty of separating it from other tocotrienol isomers. Therefore, in this study, <em>Y. lipolytica</em> was engineered for high-level δ-tocotrienol production using a multipronged strategy. Heterologous δ-tocotrienol pathway gene expression and precursor supply enhancement facilitated the production of 2.8 mg/L δ-tocotrienol. Transcriptomic analysis and metabolic modeling (iYALI743) identified four transporters that markedly improved the δ-tocotrienol titer to 4.68 mg/L. Moreover, PpHPD and SyHPT protein fusion, and the truncation of the N-terminal signal peptide of AtTC, which enhanced plant enzyme performance in <em>Y. lipolytica</em>, raised the δ-tocotrienol titer to 54.67 mg/L. Under optimized fermentation conditions with antioxidant butylated hydroxytoluene (BHT) supplementation, the engineered strain achieved a δ-tocotrienol titer of 617.23 mg/L in a 2 L bioreactor, representing the highest yield on record.</div></div>","PeriodicalId":8766,"journal":{"name":"Biochemical Engineering Journal","volume":"228 ","pages":"Article 110079"},"PeriodicalIF":3.7,"publicationDate":"2026-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145923133","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Lignin valorization to polyhydroxyalkanoates via microbial co-cultured and genome reduction method","authors":"Yi-Fei Zhang ,&nbsp;Dong Wang ,&nbsp;Yin-Ping Wang ,&nbsp;Zhong-Wei Fan ,&nbsp;Jian Liu ,&nbsp;Shi-Lei Yu ,&nbsp;Jia-Qi Cui","doi":"10.1016/j.bej.2026.110080","DOIUrl":"10.1016/j.bej.2026.110080","url":null,"abstract":"<div><div>The utilization of agricultural waste as a renewable carbon source for biopolymer production represents a critical component of the circular economy. To enhance the bioconversion efficiency of bio-based polymers, a co-cultured system and a genome reduction method were employed to improve lignin valorization. <em>Pseudomonas putida</em> KT2440 exhibited higher lignin bioconversion capacity than other evaluated strains. When co-cultured with <em>Bacillus</em> sp. S0, the dry cell weight (DCW) and polyhydroxyalkanoate (PHA) concentration increased to 1.6 g/L and 42.6 mg/L, respectively, compared with <em>P. putida</em> KT2440 alone. Lignin valorization was further enhanced when the genome-reduced strain <em>P. putida</em> KTU-13 was co-cultured with <em>Bacillus</em> sp. S0. After optimizing key fermentation parameters, including nitrogen content, inoculation rate, and strain ratio, the DCW and PHA concentration reached 2.0 g/L and 67.1 mg/L, respectively. Overall, this work demonstrates a sustainable approach for improving bio-based polymer production through integrated process optimization.</div></div>","PeriodicalId":8766,"journal":{"name":"Biochemical Engineering Journal","volume":"228 ","pages":"Article 110080"},"PeriodicalIF":3.7,"publicationDate":"2026-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145974053","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Optimum biohydrogen production by combination of fermentation and microbial electrolysis cell: Bioreactor design, scale-up, and technology readiness level analysis","authors":"Vikash,&nbsp;Nitai Basak","doi":"10.1016/j.bej.2025.110066","DOIUrl":"10.1016/j.bej.2025.110066","url":null,"abstract":"<div><div>The integration of fermentation with microbial electrolysis cells (MECs) presents a novel approach to enhance biohydrogen production from organic residues, thereby overcoming the limitations of traditional fermentation systems. This review critically assesses the current state of this combined technology, focusing on bioreactor engineering, scale-up challenges, and its readiness for commercial application. The fermentation stage effectively converts complex biomass into a volatile fatty acid (VFA) rich effluent, which serves as an ideal substrate for the subsequent MEC to achieve near-complete substrate valorisation and significantly higher hydrogen yields. Analysis of bioreactor design reveals a clear trend toward reducing capital costs through the development of low-cost, non-precious metal cathode catalysts, such as nickel alloys and stainless steel, to replace platinum, as well as the adoption of simplified, membraneless reactor architectures. The comprehensive Technology Readiness Level (TRL) assessment places the system at TRL 3–4. However, scaling this technology from the laboratory to industrial application presents considerable challenges. We conclude that bridging the gap to pilot-scale (TRL 6) requires overcoming specific engineering hurdles such as maintaining high current densities in large-scale reactors, mitigating biofouling, and optimizing various biological and physical factors affecting biohydrogen yield in fermentation and MEC systems.</div></div>","PeriodicalId":8766,"journal":{"name":"Biochemical Engineering Journal","volume":"228 ","pages":"Article 110066"},"PeriodicalIF":3.7,"publicationDate":"2026-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145883666","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Purple-red azaphilone alkaloids from Talaromyces amestolkiae showing antimicrobial activity","authors":"Fernanda de Oliveira ,&nbsp;Caio de Azevedo Lima ,&nbsp;Diana Cláudia Gouveia Alves Pinto ,&nbsp;Laura Carmona Ferreira ,&nbsp;Tais Maria Bauab ,&nbsp;Silvio Silvério da Silva ,&nbsp;Valéria Carvalho Santos-Ebinuma","doi":"10.1016/j.bej.2025.110065","DOIUrl":"10.1016/j.bej.2025.110065","url":null,"abstract":"<div><div>The global rise of antimicrobial resistance highlights the urgent need for alternative bioactive compounds from sustainable sources. Fungal colorants, especially azaphilones, represent promising natural molecules due to their structural diversity, colorant properties, and biological activities. <em>Talaromyces amestolkiae</em> is a well-known source of Monascus-like azaphilone colorants free of mycotoxins, yet its antimicrobial potential and production dynamics remain underexplored. In this study, submerged cultivations were conducted to improve colorant production, isolate novel compounds, and assess antimicrobial activity. The effects of glucose concentration and hydrodynamic conditions, expressed through agitation, aeration, and the volumetric oxygen transfer coefficient (k_La), were investigated. The optimal condition (100 rpm, 1.0 vvm, 10 g·L⁻¹ of glucose) promoted balanced oxygen availability and carbon utilization, resulting in maximum colorant yield. Two novel purple-red azaphilone alkaloids, <em>cis</em>-amestolkin (1) and <em>trans</em>-amestolkin (2), were isolated and characterized by UV–Vis, LC-HRMS, and NMR spectroscopy. These compounds are geometric isomers of nitrogen-containing azaphilones featuring a γ-lactone ring and a unique 4-amino-6-hydroxyhexanoic acid moiety. Antimicrobial assays revealed that <em>T. amestolkiae-</em>derived metabolites exhibit pronounced inhibitory activity against <em>Pseudomonas aeruginosa</em>, <em>Staphylococcus aureus</em>, and <em>Salmonella setubal</em>, highlighting their bioactive potential . This work integrates bioprocess improvement with metabolite identification and biological evaluation, underscoring the value of fungal colorants as multifunctional, sustainable agents for industrial and pharmaceutical applications.</div></div>","PeriodicalId":8766,"journal":{"name":"Biochemical Engineering Journal","volume":"228 ","pages":"Article 110065"},"PeriodicalIF":3.7,"publicationDate":"2026-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145923135","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Corrigendum to “Use of free nitrous acid from partial nitrification reactor for the sanitization of digester effluents and Class A biosolids production” [Biochem. Eng. J. 226 (2026) 109993]","authors":"Zeinab Morhell ,&nbsp;Gabriel Martínez ,&nbsp;Oscar Franchi ,&nbsp;Dafne Crutchik ,&nbsp;Cristofer Da Silva ,&nbsp;Lorna Guerrero ,&nbsp;Alba Pedrouso ,&nbsp;Ángeles Val del Río ,&nbsp;Anuska Mosquera-Corral ,&nbsp;José Luis Campos","doi":"10.1016/j.bej.2026.110077","DOIUrl":"10.1016/j.bej.2026.110077","url":null,"abstract":"","PeriodicalId":8766,"journal":{"name":"Biochemical Engineering Journal","volume":"228 ","pages":"Article 110077"},"PeriodicalIF":3.7,"publicationDate":"2026-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146073970","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}