{"title":"Apo-lipoprotein A1 in the Endometria of Patients with Polycystic OvarySyndrome","authors":"O. Abdelfattah, T. MohammedSallam","doi":"10.4172/2376-127X.1000314","DOIUrl":"https://doi.org/10.4172/2376-127X.1000314","url":null,"abstract":"Objective: This clinical trial aimed at assessing the levels of apo-lipoprotein A1 in the endometria of patients with polycystic ovary syndrome (PCOS). Setting: El-Demerdash Hospital, over a 2 years period, between September 2015 and January 2017. Patients: this clinical trial involved 50 patients (age range 20-35 years) arranged into two equal groups. Group I (25 patients) which includes women with PCOS and were collected from the infertility outpatient clinic while group II (25 patients) parous women, they were presented to us due to any cause other than inability to conceive as a control group. Methods: Endometrial brushing was performed to get endometrial samples from all consented women. ELIZA was used to detect the expression of Apo-lipoprotein A1 (Apo A1) in the endometrial samples. Two endometrial samples were gathered from every patient, the first one was collected when the largest ovarian follicle is ≥ 20 mm (proliferative phase) while the second one was collected 5 days following the first one (secretory phase). Results: Interestingly, endometria of infertile women with PCOS had expressed apo-lipoprotein A1 in higher levels than the endometria of infertile women. Also, this study proved that the expression of this protein was more in the proliferative rather than secretory phase of the menstrual cycle (P value<0.05). Conclusion: It is apparent that there is an inverse relationship between apo-lipoprotein A1 and the degree of receptivity of the endometria in women with PCOS. Also, this clinical trial found a fluctuation of the level of this protein all through the menstrual cycle, being higher in the proliferative phase and less in the secretory phase when the endometrium is receptive for embryos (window of implantation).","PeriodicalId":87313,"journal":{"name":"Journal of pregnancy and child health","volume":"4 1","pages":"1-3"},"PeriodicalIF":0.0,"publicationDate":"2017-04-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42256945","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Is IVF/ICSI with Fresh Embryo Transfer Associated with Higher Mean Singleton Birth Weight Compared to Spontaneous Conception?","authors":"K. Neumann, C. Cirkel, D. Beyer","doi":"10.4172/2376-127X.1000312","DOIUrl":"https://doi.org/10.4172/2376-127X.1000312","url":null,"abstract":"Introduction: To investigate for differences in birth weight between singletons born after in vitro fertilization (IVF) or intra-cytoplasmic sperm injection (ICSI) with fresh embryo transfer versus singletons born after spontaneous conception. Materials and methods: Retrospective analysis of singleton live birth weight after IVF or ICSI with fresh embryo transfer and live birth weight of singletons born after spontaneous conception during a twelve years period in a German university hospital. Patients were treated at the fertility unit of the university hospital. Inclusion criteria were defined as singleton delivery, delivery after spontaneous conception and fresh embryo transfer after IVF/ICSI treatment. Multivariate regression analysis was used to investigate the relationship between the dependent variable z-score (fetal birth weight) and the independent predictor variables maternal age and way of conception (spontaneous conception versus conception after IVF/ICSI with fresh embryo transfer). Results: In total, 6,786 singleton live births met the inclusion criteria and were analysed: 276 live births (151 males/125 females) after IVF/ICSI with fresh transfer and 6,510 live births after spontaneous conception (3,125 male/3,385 female). Mean z-score was -0.11 (± 0.92) for IVF/ICSI and fresh embryo transfer and 0.009 (± 0.9) for spontaneous conception. Z-scores depicted no inter-group differences (p=0.295). Multivariate regression analysis indicated way of conception (conception after IVF/ICSI and fresh transfer and spontaneous conception) but not maternal age as significant predictor of fetal birth weight. Conclusion: There is no association between IVF/ICSI with fresh embryo transfer and mean singleton birth weight compared to birth weight after spontaneous conception.","PeriodicalId":87313,"journal":{"name":"Journal of pregnancy and child health","volume":" ","pages":"1-4"},"PeriodicalIF":0.0,"publicationDate":"2017-04-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.4172/2376-127X.1000312","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43989374","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
S. Alouini, Rason, rianina Bienvenue Solange, Anna Ramos, N. Ayass, R. Rado, riamboavonjy
{"title":"Short-term Survival and Morbidity of Extremely premature Infants Born between 20 Weeks and 24 Weeks+6 Days Gestation","authors":"S. Alouini, Rason, rianina Bienvenue Solange, Anna Ramos, N. Ayass, R. Rado, riamboavonjy","doi":"10.4172/2376-127X.1000311","DOIUrl":"https://doi.org/10.4172/2376-127X.1000311","url":null,"abstract":"Objective: To evaluate the morbidity and mortality of extremely premature infants (EPIs) born between 20 weeks and 24 weeks+6 days gestation at hospital discharge. Methods: This was a retrospective study that included all extremely preterm births between 2006 and 2012 at a tertiary maternity care centre with a neonatal intensive care unit. Results: Seventy-eight EPIs were born during the study period out of 30,000 deliveries (0.26%). Thirty-nine EPIs (50%) survived and had a mean length of hospital stay of 43 days. The mean weight of EPIs was 723 ± 179 g. The rate of survival of EPIs increases with gestational age. Forty-nine EPIs (62%) exhibited neonatal respiratory distress (NNRD), which evolved into a bronchopulmonary dysplasia in 28 cases (35%); 33 EPIs (42%) had a maternofetal infection, while 20 (26%) experienced ventricular hemorrhage. Ten EPI (13%) displayed enterocolitis and 17 (22%) had retinopathy. No EPIs born before 22 weeks gestation survived Twenty-four EPIs left the hospital with their mothers after being scheduled for a routine paediatric follow-up visit and 15 were transferred to another hospital: 10 for surgical treatment of patent ductus arteriosus and 5 to be closer to their mothers. Conclusion: The survival rates of EPIs between 20 and 24 weeks of gestation are high. NNRD, infections, and neurological and retinal complications were the main causes of morbidity. The results of this active management study of extremely preterm births were satisfactory at the short follow-up visits. Antenatal corticosteroids and magnesium sulfate administration should be discussed beginning at 22 weeks of gestation.","PeriodicalId":87313,"journal":{"name":"Journal of pregnancy and child health","volume":" ","pages":"1-5"},"PeriodicalIF":0.0,"publicationDate":"2017-04-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.4172/2376-127X.1000311","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49602585","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Evaluation of Food Behaviour and Nutritional Status of Pregnant WomenResident in Keserwan","authors":"Cynthia Zgheib, J. Matta, Y. Sacre","doi":"10.4172/2376-127X.1000331","DOIUrl":"https://doi.org/10.4172/2376-127X.1000331","url":null,"abstract":"Pregnancy, this particular moment in the life of a woman, requires monitoring of eating behaviour changes. However the food choices during pregnancy should be healthy, including the consumption of different food groups, and nutritional status is the process of acquisition and consumption of food. So a varied diet is associated with good nutritional status. This is why the nutrition education is a strategy commonly applied to improve maternal nutrition during pregnancy. Therefore, it is crucial to assess \"the eating behaviour and nutritional status of pregnant women living in Keserwan.\" The purpose of this study is to evaluate the feeding behaviour, nutritional status and level of awareness of pregnant women residing in Keserwan. A cross-sectional descriptive study is carried out, two main types of research instruments. A questionnaire containing socio-demographic, personal information, questions on eating behaviour, food frequency and nutritional education. As well as laboratory tests already done by pregnant women. The total sample surveyed included 150 pregnant women between the ages of 18 and 40 years randomly selected from the hospitals and clinics of the Keserwan gynaecologists and allocated in an equitable manner between two regions chosen according to altitude. The final analysis led to the results obtained 48.7% of pregnant women are aged 30 to 40 years, 56% have a normal BMI between 18.5 and 24.9, 80.7% have acceptable food behaviour, 68% have an acceptable level of awareness and half have an acceptable nutritional status. Thus, age affects the eating behaviour, so more women that are pregnant are older plus they have good eating behaviour. It would be possible to institute an awarenessraising program in the aim of increasing the level of education of pregnant women with regard to eating behaviour and nutritional status.","PeriodicalId":87313,"journal":{"name":"Journal of pregnancy and child health","volume":" ","pages":"1-5"},"PeriodicalIF":0.0,"publicationDate":"2017-04-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43518668","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Late Onset Congenital Adrenal Hyperplasia Presenting at Puberty with Ambiguous Genitalia: Surgery with Dexamethasone Resulting in Live New-born Normal Child","authors":"K. Kaur, G. Allahbadia, M. Singh","doi":"10.4172/2376-127X.1000310","DOIUrl":"https://doi.org/10.4172/2376-127X.1000310","url":null,"abstract":"Hirsutism is normally found with raised androgens along with excessive hair in the female giving a male like pattern and rarely in anovulation may a female present with virilization extreme in just simple PCOS. But here we present a girl who presented with late onset congenital hyperplasia who presented at puberty with development of ambiguous genitalia giving the impression of a fall causing it but investigations revealed a normal karyotype &raised 17 hydroxy progesterone with marked stimulation with ACTH and examination under anesthesia revealing a normal female like pattern after which her external genitalia were refashioned and she conceived after getting married on dexamethasone giving birth to an apparently normal daughter.","PeriodicalId":87313,"journal":{"name":"Journal of pregnancy and child health","volume":"2017 1","pages":"1-3"},"PeriodicalIF":0.0,"publicationDate":"2017-04-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"45436740","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Shu-Mei Li, C. Shan, Yue Yang, Qianyun Wang, L. Xiong
{"title":"Analysis on Medical Insurance Status of the Elderly in Urban Shaanxi Province of China","authors":"Shu-Mei Li, C. Shan, Yue Yang, Qianyun Wang, L. Xiong","doi":"10.4172/2376-127X.1000309","DOIUrl":"https://doi.org/10.4172/2376-127X.1000309","url":null,"abstract":"Objective: This paper contributed to summarize researches of population aging and medical insurance in China and Shaanxi Province and worked out the health service demands and medical insurance status of the elderly in Shaanxi Province. Moreover, it demonstrated the present situation and challenges of medical insurance of the elderly in urban areas in Shaanxi Province and explored effective ways of optimizing the medical insurance system of the elderly in urban China. Methods: Methods including cluster random sampling, questionnaire survey and interview were conducted. Data analysis was performed by SPSS 21.0. And logistic regression analysis was used to analyse factors that affected the satisfaction rate. Results: 1. The covering rate of China’s urban basic medical insurance among interviewees is high (96.0%). 2. The ratio of reimbursement of hospitalization expenses (73.2%) was much higher than that of outpatient services (22.0%). 3. Self-paid expenses for outpatients on hypertension, hyperlipidemia and diabetes were high for 90.3%, 87.7% and 85.2%. 4. Interviewees who lived close to the nearest medical institution, participated in commercial medical insurances, had no physical examinations within one year and had bad subjective health status were more possible to be satisfied with the social basic medical insurance system. Conclusion: The country should provide the elderly with convenience and new ways to meet their medical demands by strengthening preventions of chronic diseases of the elderly, improving the security level of the urban basic medical insurance and perfecting reimbursement system of medical expenses paid in other cities.","PeriodicalId":87313,"journal":{"name":"Journal of pregnancy and child health","volume":"2017 1","pages":"1-8"},"PeriodicalIF":0.0,"publicationDate":"2017-04-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.4172/2376-127X.1000309","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49474996","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Damar Prasmusinto, Rosalyn C Jono, Yuyun Lisnawati
{"title":"Neutrophil Lymphocyte Ratio and Red Cell Distribution Width as a Marker of Preeclampsia: A Retrospective Study","authors":"Damar Prasmusinto, Rosalyn C Jono, Yuyun Lisnawati","doi":"10.4172/2376-127X.1000307","DOIUrl":"https://doi.org/10.4172/2376-127X.1000307","url":null,"abstract":"Background: Preeclampsia occurs in 3-7% of pregnancy and contributes to 18% maternal mortality. Unfortunately, proper diagnosis and prompt treatment for preeclampsia are lim ited in rural area due to limited facilities. Neutrophils, lymphocytes, and red distribution width, some of the inflammatory response, are considered as marker for preeclampsia. We evaluated the NTR and RDW as a reliable marker for preeclampsia in limited facilities health care. Methods: A retrospective study was conducted to 254 pregnancies at Persahabatan Hospital, Jakarta, Indonesia. We obtained NTR and RDW data from the complete blood count panels and differed to two groups: pregnancies with preeclampsia and not, early and late onset of preeclampsia. We analyzed with T-test and Mann- Whitney test using SPSS 20.0 and performed diagnostic analysis in investigating sensitivity and specificity of NTR and RDW as marker tools. Results: There were 136 pregnancies with preeclampsia and 118 normal pregnancies. Pregnancies with preeclampsia showed higher NTR with mean 4.41 (95% CI 1.41-32.54, p<0.001) and RDW with median 14.2 (95% CI 1.48-23.90, p<0.001). Onset of preeclampsia did not influence the NTR with median of early onset preeclampsia 4.35 (95%CI 1.41-17.56) and late onset of preeclampsia 4.41 (95% CI 1.69-32.54). Hence, RDW showed statistically significance (power 97.29%, p<0.001) as higher range was obtained in the late onset of preeclampsia (95% CI 14.91 ± 2.16) that in the early onset of preeclampsia (95% CI 13.50 ± 1.47). In ROC (Receiver Operating Characteristic) curve analysis, NTR become an important marker for preeclampsia with sensitivity 80.1% and specificity 87.3% (95%CI 0.85-0.93, cut off value 3.295). RDW shows sensitivity 50.7% and specificity 71.2% (95%CI 0.55-0.69, cut off value 14.17). Conclusion: NTR and RDW can be markers for preeclampsia as higher NTR and RDW, as inflammatory responses, may be related to preeclampsia.","PeriodicalId":87313,"journal":{"name":"Journal of pregnancy and child health","volume":"4 1","pages":"1-4"},"PeriodicalIF":0.0,"publicationDate":"2017-03-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.4172/2376-127X.1000307","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42764129","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
H. Dağdeviren, Ç. Helvacıoğlu, Ammar Kanawati, C. Kaya, H. Cengiz
{"title":"Posterior Vaginal Wall Cyst Mimicking Rectocele","authors":"H. Dağdeviren, Ç. Helvacıoğlu, Ammar Kanawati, C. Kaya, H. Cengiz","doi":"10.4172/2376-127X.1000306","DOIUrl":"https://doi.org/10.4172/2376-127X.1000306","url":null,"abstract":"Vaginal wall cysts occur rarely and can cause a variety of symptoms. A 35-year-old woman presented with history of mass bulging from vagina for a-year. Pelvic examination revealed a reducible non-tender mass protruding from the vagina and diagnosed as rectocele. Physical examination is important for the detection and characterization of vaginal cysts but may be inadequate for appropriate diagnosis.","PeriodicalId":87313,"journal":{"name":"Journal of pregnancy and child health","volume":" ","pages":"1-2"},"PeriodicalIF":0.0,"publicationDate":"2017-03-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.4172/2376-127X.1000306","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46170724","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
L. Audrey, C. Martel-Billard, N. Sananès, B. Viville, B. Langer
{"title":"Management of Extremely Preterm Births in the Level III Maternity Unit atStrasbourg University Hospital Centre (CHU)","authors":"L. Audrey, C. Martel-Billard, N. Sananès, B. Viville, B. Langer","doi":"10.4172/2376-127X.1000304","DOIUrl":"https://doi.org/10.4172/2376-127X.1000304","url":null,"abstract":"Introduction: Active management of extreme prematurity, defined as birth occurring before 26WG, has medical and familial repercussions on account of the uncertain future of these infants. The aim of this paper is to describe our experience in the obstetrical and paediatric management of extreme preterm births based on choices made by the families. Methods: We retrospectively included all infants born between 22WG and 25WG+6days in our level III maternity unit in the period from January 2010 to December 2014. These births were documented along with family choices, methods of obstetrical management and birth outcomes. Results: 166 infants were included. After 24WG, active management was requested by the parents in 90% of cases versus 13% at 23WG and none at 22WG. Corticosteroid therapy was administered in 0% of cases at 22WG, 19% at 23WG, 92% at 24WG and 94% at 25WG. Caesarean section was performed in 0% of cases before 24WG, 10% at 24WG and 48% at 25WG. Six per cent of infants at 22WG, 32% at 23WG, 89% at 24WG and 92% at 25WG were live births. The survival rate for infants admitted to neonatal intensive care was 17% at 23WG, 47% at 24WG and 71% at 25WG. Conclusion: Optimal management of extreme preterm births requires a solidly cooperative obstetrical-paediatric team guided by respect for parental choice.","PeriodicalId":87313,"journal":{"name":"Journal of pregnancy and child health","volume":"2017 1","pages":"1-7"},"PeriodicalIF":0.0,"publicationDate":"2017-02-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.4172/2376-127X.1000304","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41561353","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Community Based Magnitude of Obstetric Emergencies in Rural Women withLow Resources","authors":"S. Chhabra","doi":"10.4172/2376-127X.1000303","DOIUrl":"https://doi.org/10.4172/2376-127X.1000303","url":null,"abstract":"Background: Rural women with low resources do not get timely and appropriate care for obstetric emergencies. Awareness in women, communities about emergencies, action needed, helps in getting quick, right therapy for prevent ion of maternal, perinatal morbidity, mortality. Objective: To know community based numbers, types of emergencies for which rural women sought care during pregnancy, labour, postpartum. Methodology: Present article is based on analysis of records of women who sought referral care for emergencies during pregnancy, labour, postpartum from communities of 53 villages with low resources, being served through nurse midwives. Results: Of 10117 births in 53 villages during analysis period, 656 (6.48 %) women sought emergency care. 458 (7.52% of 6087 births) were from nearby villages, being served since more than two and half decades (called old), 198 (4.91% of 4030 births) from far off villages, being served since around one and half decade (called new). Emergency services were for placental abruption, hypertensive disorders, obstructed labour (due to cephalopelvic disproportion or abnormal presentation), non-progress of labour or postpartum haemorrhage, with no significant change over years. Maternal deaths due to pregnancy, labour, post-partum complications have been almost eliminated. Perinatal mortality has reduced, though it is still high. No woman reported with septic abortion or rupture uterus in last decade. In old villages, 44% were home births between 1987-1990, 6.2% between 2011-2014. In new 38.2% were home births between 1996 to 1999 and 12.40% between 2011-2014. Conclusion: Nurse midwives can do a lot for prevention of fatal emergencies, maternal, perinatal deaths with some limitations. About some disorders more information is needed for best of heal7th of women. Research needs to continue.","PeriodicalId":87313,"journal":{"name":"Journal of pregnancy and child health","volume":" ","pages":"1-5"},"PeriodicalIF":0.0,"publicationDate":"2017-02-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44476195","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}