Late Onset Congenital Adrenal Hyperplasia Presenting at Puberty with Ambiguous Genitalia: Surgery with Dexamethasone Resulting in Live New-born Normal Child
{"title":"Late Onset Congenital Adrenal Hyperplasia Presenting at Puberty with Ambiguous Genitalia: Surgery with Dexamethasone Resulting in Live New-born Normal Child","authors":"K. Kaur, G. Allahbadia, M. Singh","doi":"10.4172/2376-127X.1000310","DOIUrl":null,"url":null,"abstract":"Hirsutism is normally found with raised androgens along with excessive hair in the female giving a male like pattern and rarely in anovulation may a female present with virilization extreme in just simple PCOS. But here we present a girl who presented with late onset congenital hyperplasia who presented at puberty with development of ambiguous genitalia giving the impression of a fall causing it but investigations revealed a normal karyotype &raised 17 hydroxy progesterone with marked stimulation with ACTH and examination under anesthesia revealing a normal female like pattern after which her external genitalia were refashioned and she conceived after getting married on dexamethasone giving birth to an apparently normal daughter.","PeriodicalId":87313,"journal":{"name":"Journal of pregnancy and child health","volume":null,"pages":null},"PeriodicalIF":0.0000,"publicationDate":"2017-04-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Journal of pregnancy and child health","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.4172/2376-127X.1000310","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 0
Abstract
Hirsutism is normally found with raised androgens along with excessive hair in the female giving a male like pattern and rarely in anovulation may a female present with virilization extreme in just simple PCOS. But here we present a girl who presented with late onset congenital hyperplasia who presented at puberty with development of ambiguous genitalia giving the impression of a fall causing it but investigations revealed a normal karyotype &raised 17 hydroxy progesterone with marked stimulation with ACTH and examination under anesthesia revealing a normal female like pattern after which her external genitalia were refashioned and she conceived after getting married on dexamethasone giving birth to an apparently normal daughter.