Bangladesh Journal of Medical Science最新文献

{"title":"Keystone design perforator island flap: our experience for coverage of lower limb defects","authors":"Md Salek Bin Islam, Md. Zalal Uddin, Md Ahsan Habib, Md Mahbubur Rahman, Foara Tasmim, MA Kalam, Ms Zebun Nahar","doi":"10.3329/bjms.v22i4.67117","DOIUrl":"https://doi.org/10.3329/bjms.v22i4.67117","url":null,"abstract":"The fusion of concept of perforasome and trapezoid design made Keystone design Perforator Island flap (KDPIF). This flap was first introduced by Behan in 2003 and since then many modifications were done. Keeping the principles of KDPIF, two modifications were done in this study.\u0000Aims: to determine reliability and advantages of KDPIF for lower limb defect coverage.\u0000Materials and Methods:15 cases were done in Plastic surgery department of Rajshahi Medical College Hospital from October 2020 to September 2022.\u0000Results: The largest wound measuring 11X 10 cm2 on thigh defect following wide local excision of sarcoma was covered by the largest dimension flap measuring 16X 11 cm2. In most of the cases (7 cases), Type IIA KDPIF was done. With co-morbidities, 14 flaps survived without any complications. Range operating time was 35-110 minutes.\u0000Conclusion: Due to its reliable vascularity and easy execution and good outcomes, KDPIF is one of the best choices for lower limb defect coverage.\u0000Bangladesh Journal of Medical Science Vol. 22 No. 04 October’23 Page : 920-925","PeriodicalId":8696,"journal":{"name":"Bangladesh Journal of Medical Science","volume":"104 1","pages":""},"PeriodicalIF":0.9,"publicationDate":"2023-09-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"78034654","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Pharmacology Teaching by Concept Map Method","authors":"S. A. Rashid, Syed Ziaur Rahman","doi":"10.3329/bjms.v22i4.67119","DOIUrl":"https://doi.org/10.3329/bjms.v22i4.67119","url":null,"abstract":"Abstract not available\u0000Bangladesh Journal of Medical Science Vol. 22 No. 04 October’23 Page : 942-944","PeriodicalId":8696,"journal":{"name":"Bangladesh Journal of Medical Science","volume":"23 1","pages":""},"PeriodicalIF":0.9,"publicationDate":"2023-09-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"90419883","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Abnormal uterine bleeding in women of reproductive age: PALM-COEIN causes","authors":"Kateryna Fedosiuk, Lyudmyla Pakharenko, Kirill Chayka, Iryna Basiuha, Oleg Kurtash","doi":"10.3329/bjms.v22i4.67116","DOIUrl":"https://doi.org/10.3329/bjms.v22i4.67116","url":null,"abstract":"Objective: Abnormal uterine bleeding (AUB) is an often pathology in women of reproductive age.\u0000Materials and methods. The retrospective analysis of 336 patients with AUB was performed between 2017-2020. We analyzed the social and demographic data, reproductive function, somatic diseases, type and causes of AUB.\u0000Results. According to PALM-COEIN classification polyps were found in 13.39 % of patients, adenomyosis – 20.83 %, leiomyoma – 37.50 %, malignancy/hyperplasia – 14.29 %, ovulation disorders – 24.11 %, endometrial factor – 12.20 %, iatrogenic reason – 6.25 %.\u0000Conclusion. PALM-causes dominate over COEINetiological factors in the development of AUB in women of reproductive age. But, there are some differences in the rate of causes according to the age period.\u0000Bangladesh Journal of Medical Science Vol. 22 No. 04 October’23 Page : 809-814","PeriodicalId":8696,"journal":{"name":"Bangladesh Journal of Medical Science","volume":"57 1","pages":""},"PeriodicalIF":0.9,"publicationDate":"2023-09-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"85711024","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Involvement of ACE2 in the intestinal transport of amino acids: Possible health and nutritional consequences in altered expression","authors":"Jesmine Khan, Wan Nor I’zzah Wan Mohamad Zain, M. N. Islam","doi":"10.3329/bjms.v22i4.67115","DOIUrl":"https://doi.org/10.3329/bjms.v22i4.67115","url":null,"abstract":"Background:Absorption of neutral amino acids across the intestinal cells is mediated by the broad neutral amino acid transporter B0AT1. Intestinal expression of B0AT1 depends on the coexistence with the membrane-attached angiotensin-converting enzyme 2 (ACE2) which binds to the B0AT1 or the sodium-dependent imino-acid transporter 1 (SIT1) in the intestinal epithelial cells.\u0000Objectives:The objective of this article is to provide an overview of the involvement of ACE2 in the transport of amino acids from the intestinal lumen and possible harmful effects on health and nutrition due to altered ACE2 expression.\u0000Methods: PubMed, Scopus, and Google Scholar were searched using the keywords ACE2 paired with intestinal and gut B0AT1, SIT1, amino acid transport or absorption, health, and nutrition. Expression of B0AT1 in the intestine was completely absent in ACE2 knockout mice. Lack of ACE2 and B0AT1 expression lead to low plasma and muscle tryptophan, niacin deficiency, decreased intestinal antimicrobial peptide, and increased susceptibility to inflammatory bowel disease in animal models.\u0000Results: Expression of ACE2 in the small intestine and its association with amino acid transporters play a crucial role in the absorption of amino acids, maintenance of structural and functional gut integrity and overall health and nutrition status of an individual.\u0000Bangladesh Journal of Medical Science Vol. 22 No. 04 October’23 Page : 729-733","PeriodicalId":8696,"journal":{"name":"Bangladesh Journal of Medical Science","volume":"67 1","pages":""},"PeriodicalIF":0.9,"publicationDate":"2023-09-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"76213496","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Legal Responses to Violence against Medicare Service Persons and Institutions during COVID- 19 Pandemic in India","authors":"M.Z.M. Nomani, Hekmatullah Mulki, Merwais Niazy, N. A. Nusrati, Mohd Yasin Wani, Abdullah Samdani","doi":"10.3329/bjms.v22i4.67121","DOIUrl":"https://doi.org/10.3329/bjms.v22i4.67121","url":null,"abstract":"Background: The COVID-19 pandemic and virility of the violence against medical personnel have been parallel phenomena in Indian public health administration. The safety and security medical and paramedical have been attracting attention for quite a long time. Still, no central legislation has piloted to enhance their therapeutic and surgical acumen in epidemics and pandemics. The health care of the patients and the covenant of Medicare service persons and institutions doctors missed in the myopic perception of the health administration’s tilt towards the criminal administration of justice.\u0000Method: The clasping of 125 years of age epidemic control law and 162 years of age criminal statute stinks the Indian feel in the present context.\u0000Result: The significant outcome of the COVID-19 pandemic is showcased in the Epidemic Diseases (Amendment) Ordinance, 2020, ensuring harassment-free workplaces for the medical fraternity. The criminal sanction afforded by the 23 state enactments on the protection of medical care personnel and institutions in states in India, but there is no central legislation. Despite the Indian Medical Association’s recommendation for the Protection of Medical Service Persons and Medical Service Institutions (Prevention of Violence and Damage or Loss of Property) Act, 2017, we witnessed Epidemic Diseases (Amendment) Ordinance, 2020 in enhancing the robust workplace for the doctors during the pandemic. The legal strategy camouflaging ‘disaster’ under Section 2 (d) of the Disaster Management Act, 2005 in pandemic and lockdown is sobering but astonishing.\u0000Conclusion: The paper locates the legal response to violence against the doctors in the sociology of medicine and medical professions as professional socialization and social system during the COVID-19 pandemic.\u0000Bangladesh Journal of Medical Science Vol. 22 No. 04 October’23 Page : 734-742","PeriodicalId":8696,"journal":{"name":"Bangladesh Journal of Medical Science","volume":"26 1","pages":""},"PeriodicalIF":0.9,"publicationDate":"2023-09-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"83502339","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Overweight and Obesity and its Associated Factors Among Office Staff at a Higher Education Institute in Malaysia.","authors":"Nurul Aini Binti Mohamad Zabuddin, Mohamad Aiman Arief Bin Jamaludin, M. Pasha, Abdus Salam","doi":"10.3329/bjms.v22i4.67122","DOIUrl":"https://doi.org/10.3329/bjms.v22i4.67122","url":null,"abstract":"Introduction: Overweight and obesity caused by excess body fat accumulation is a leading public health problem globally. The objective of this study was to investigate the overweight and obesity prevalence and its accompanying factors among educational office staff in Kuantan, Malaysia.\u0000Materials and Methods: A cross-sectional study was conducted among the staff of Widad University College (WUC) and Widad College (WC) using a self-administered validated questionnaire. Socio-demographic characteristics of the participants and obesity-related health information such as body mass index (BMI), smoking, alcoholics, physical activities and blood pressure status were obtained. The BMI was determined considering the participants weight in kilograms (kg) divided by the square of height in meters (kg/m2). Correlating the BMI with sociodemographic and health-related factors, the participants were characterized as underweight, normal, overweight and obese and presented as mean, frequency and percentage distribution. A p-value of <0.05 means a statistically significant result.\u0000Results: Overweight prevalence was 28.3% while obesity was 16.2 %. There were 13% of respondents underweight. A higher rate was found in males and Malay participants. Age, education, occupation, income, smoking, alcoholics, physical inactivity and hypertension were significantly linked to BMI.\u0000Conclusions: Overweight and obese constitute around 44% of the staff at WUC and WC, while 13 % were underweight. It is necessary to motivate employees through an effective training program organized by the employer towards maintaining a healthy lifestyle and thereby maintaining good health and improving work performance.\u0000Bangladesh Journal of Medical Science Vol. 22 No. 04 October’23 Page : 833-841","PeriodicalId":8696,"journal":{"name":"Bangladesh Journal of Medical Science","volume":"52 1","pages":""},"PeriodicalIF":0.9,"publicationDate":"2023-09-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"86210355","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Comparison of Bacterial Etiology with Antibiogram of Blood Stream Infection between Adult and Paediatric Group at a Tertiary Care Hospital in Bangladesh","authors":"Tarana Jahan, Md Abdullah Yusuf, S. Shahid, Siddika Khatun, S. Sultana, Kajol Akter, Anika Farzin, SM Moniruzzaman","doi":"10.3329/bjms.v22i4.67126","DOIUrl":"https://doi.org/10.3329/bjms.v22i4.67126","url":null,"abstract":"Background: Timely understanding of bacterial profiles and the change of antimicrobial resistance provide an important guidance for effective and optimized use of antibiotics in local healthcare systems.\u0000Objective: The purpose of this study was to compare of bacterial etiology with antibiogram of blood stream infection between adult and paediatric.\u0000Methodology: This cross-sectional study was conducted in the department of Microbiology at Monno Medical College, Manikganj, Bangladesh during the period from January 2019 to December 2019 for duration of one year. In adult and pediatric patient blood was collected according to blood collection guidelines and inoculated into BacT/ALERT FA plus and BacT/ALERT PF plus aerobic blood culture bottles respectively. After collection these bottles were immediately incubated in BacT/ALERT 3D (manufactured by bioMerieoux, France) a fully automated blood culture system. Antimicrobial susceptibility test was done for all isolated bacteria by disc diffusion method.\u0000Result: A total number of 178 patients were recruited, among them 12 (7%) yielded growth of different bacteria. The culture positive cases were found in 7 (4%) in Paediatric group and 5 (3%) in adult age group. The most predominant identified bacteria in Paediatric group was Escherichia Coli which showed highly sensitive to imipenum, amikacin, linezolid, gentamicin (n=3, 100%). In adult group the most predominant isolated bacteria was Streptococci species which showed high sensitive to imipenum, linezolid, gentamicin 4 (80%) considerable sensitive to ciprofloxacin, tetracycline, cefotaxime, cefuroxime 3(60.0%).\u0000Conclusion: In conclusion the most common bacteria isolated from blood stream infection in adult and paediatric group are Streptococci species and Escherichia Coli respectively.\u0000Bangladesh Journal of Medical Science Vol. 22 No. 04 October’23 Page : 869-875","PeriodicalId":8696,"journal":{"name":"Bangladesh Journal of Medical Science","volume":"61 1","pages":""},"PeriodicalIF":0.9,"publicationDate":"2023-09-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"84892191","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Music listening habits of adolescents in a South Indian city","authors":"Usha Shastri, G. Spoorthi, Sharel Lopes, M. Kalaiah","doi":"10.3329/bjms.v22i4.67128","DOIUrl":"https://doi.org/10.3329/bjms.v22i4.67128","url":null,"abstract":"Objective: Universal access to personal music listening devices has attracted many adolescents to listen to music. However, risky music listening behavior can lead to music-induced hearing loss, becoming a major social and public health problem. We aimed to investigate music listening habits in three groups of adolescents based on age, learn the differences in music listening habits among the groups, if any, and assess their knowledge regarding loud music-induced hearing loss.\u0000Materials and method: A total of 300 adolescents aged 13-20 years studying in various schools and colleges of a South Indian city completed a questionnaire to understand music listening habits and knowledge regarding loud music-induced hearing loss. Based on age and education level, they were divided into three groups of 100 each [high school(HS): 13-16 years, pre-university(PU): 16-17 years, and undergraduate(UG) level: 18-20 years].\u0000Results: Duration and frequency of music listening, usage of the device, and accessory were similar among the three groups. However, across the age, there is a difference in the loudness in music listening (younger HS and PU groups frequently used loud volume) and the awareness about the damage caused to hearing due to loud music (younger HS group was least aware). A reduced hearing was reported by 17% of the UG group as opposed to 4% of the HS group.\u0000Conclusion: With the use of earphones and loud volume, younger adolescents are at greater risk for music-induced hearing loss than older adolescents. This group, if educated, is ready to accept modifications in listening behaviors that are hearing protective.\u0000Bangladesh Journal of Medical Science Vol. 22 No. 04 October’23 Page : 882-894","PeriodicalId":8696,"journal":{"name":"Bangladesh Journal of Medical Science","volume":"32 1","pages":""},"PeriodicalIF":0.9,"publicationDate":"2023-09-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"77742776","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Apple and Pear Juices as Memory Boosters: Phytochemicals Analysis and Comparative Study between Natural Fruit Juices and Memantine","authors":"Somia Gul, Rabia Badar, Qurrat-ul-ain Leghari, Faiza Akhtar, Urooba Iqbal, Tahreem Zamir, Bisma Batool","doi":"10.3329/bjms.v22i4.67123","DOIUrl":"https://doi.org/10.3329/bjms.v22i4.67123","url":null,"abstract":"Background: Our memory is a treasure, a recollection of various events from our entire life. But a number of factors like aging, stress, anxiety, depression, injury, certain disorders or use of some medications may decrease the efficacy of our brain thereby affecting our memory.\u0000Objectives: The intend of our study was to evaluate the effect of a well renowned memory enhancing drug memantine on memory with fruits like apple (Malusdomestica) which is speculated to be good for memory.\u0000Methods: This study also aimed to put forward the positive effects of pear (Pyruscommunis L.) juice on memory. While 2nd part of study included qualitative and quantitative phytochemical screenings of apple and pear with peels and without peels. For first part of study, in vivo testing has been done onto 4 groups, i.e. control group, reference group, test group A &test group B. Mice’s behavior was evaluated using two apparatus i.e. Elevated Plus Maze for 3 days & Novel Object Recognition Chamber for 2 days. While phytochemical analysis has been performed on the pericarp and mesocarp region of fresh fruits which were isolated, shade dried, blended and finely powdered.\u0000Result: Results prove that pear juice does impart positive effects on memory and can prove to be an alternative in the prevention of memory loss. Both tested fruits (apple& pear in juice/ liquid form), do pose remarkably positive effects on brain’s activity. Apple juice has shown more memory enhancing effects and was closer to that of our standard drug i.e. memantine. It can be concluded that apple and pear both contain flavonoids like quercetin and epicatechin, having antioxidant properties, which can help reverting or preventing the age-related oxidative degeneration of neurons.\u0000Conclusion: Although the memory enhancing effects of reference standard i.e. memantine is high as compare to our tested fruit juices but still it gives hope and evidenced that apple and pear juices can serve as memory enhancers to save our memory from deteriorating and active constituents from apples and pears could consider as excellent source for drug development and future pharmacological studies.\u0000Bangladesh Journal of Medical Science Vol. 22 No. 04 October’23 Page : 842-849","PeriodicalId":8696,"journal":{"name":"Bangladesh Journal of Medical Science","volume":"438 1","pages":""},"PeriodicalIF":0.9,"publicationDate":"2023-09-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"79624334","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Primary Plasma Cell Leukaemia with Lambda Light Chain secretion and Chromosomal abnormalities presenting as hyperleukocytosis - A case report.","authors":"Dr. Majed Abdul, Basit Momin, Dr. Anamika Aluri, G. Vamshi, Krishna Reddy, Dr. Rahul Dev Singh","doi":"10.3329/bjms.v22i4.67118","DOIUrl":"https://doi.org/10.3329/bjms.v22i4.67118","url":null,"abstract":"Primary plasma cell leukaemia (pPCL) is a rare and lethal form of plasma cell dyscrasia that can occur either de novo (primary) or as a leukemic transformation of refractory or relapsed multiple myeloma. We report a case of pPCL with lambda light chain disease and multiple chromosomal abnormalities in a 75-year-old female who presented with generalized weakness. Her peripheral blood smear showed hyperleukocytosis with 78% circulating plasma cells. Serum protein electrophoresis (SPE) does not reveal the M band and serum immunofixation (SI) light chain analysis in serum showed an elevated lambda light chain. Skeletal radiography and PET-CT (positron emission tomography—computerized tomography) did not reveal any lytic lesions. Immunophenotypic studies reveal a CD38-positive population with negativity for T cells, B cells, myeloid markers, and a negative CD45. Fluorescent in situ hybridization (FISH) analysis results disclosed the deletion of 13q14.3 and t(11; 14). This case highlighted the usefulness of the peripheral smear findings and high fluorescent lymphocyte activity, which directed the pathologist to initiate workup for pPCL, and comprehensive laboratory biochemical and radiological evaluation further helps to confirm and differentiate pPCL from multiple myeloma.\u0000Bangladesh Journal of Medical Science Vol. 22 No. 04 October’23 Page : 932-936","PeriodicalId":8696,"journal":{"name":"Bangladesh Journal of Medical Science","volume":"102 1","pages":""},"PeriodicalIF":0.9,"publicationDate":"2023-09-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"80646812","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}