The South Dakota journal of medicine and pharmacy最新文献

{"title":"Satisfaction of medical students with the training program at Hue University of Medicine and Pharmacy, Hue University","authors":"An Nguyen Truong, My Vo Ngoc Ha, Dong Ngo Van, Khanh Vinh, Thang Phan Van, Phuong Ha Minh, Thuan Le Thi Phuong, Hoa Nguyen Thi Nhat, Anh Vo Phuc","doi":"10.34071/jmp.2023.2.14","DOIUrl":"https://doi.org/10.34071/jmp.2023.2.14","url":null,"abstract":"Background: From the academic year 2018-2019, the University of Medicine and Pharmacy has renewed the medical training program in the direction of integration based on competence. One of the mandatory criteria is to survey the satisfaction of medical students with the training program at the Hue University of Medicine and Pharmacy, in order to validate the school’s training quality. A plethora of aspects of the training program was considered in this study, such as objectives and content of the training program, materials and facilities, teaching staff, organization of assessment, and counseling to support students.\u0000\u0000Objectives: 1) Surveying the fulfillment of medical students with the training program and 2) Finding out some factors related to student contentment with the training program. Materials and methods: Crosssectional descriptive study was applied to investigate the satisfaction of 847 medical students from 1st to 4th year at the University of Medicine and Pharmacy. The data retrieved from the Google form autocomplete toolkit consisted of 2 parts: general information and the satisfaction of medical students with the training program. Data analysis was performed using SPSS 20.0 software. Partition system description was achieved by frequency and rate. Exploratory factor analysis was employed to evaluate the reliability of the satisfactory scale of students with the training quality and the model’s suitability. Linear regression was utilized to assess the correlation of the training quality factors with the satisfaction of students.\u0000\u0000Results: Overall, 87.8% of students are content with the renewed training program. The linear regression model shows that the students’ fulfillment is determined by lecturers, objectives and contents of the program, administrative organization (structure, evaluation, and support for students), and facility-related factors (materials and training facilities).\u0000\u0000Conclusions: The satisfaction rate of students reaches 87.8%. The degree of influence of these factors on the satisfaction of medical students with the training program at the University of Medicine and Pharmacy follows a descending order: (1) teaching staff, (2) objectives and content of the training program, (3) organizing, evaluating, and supporting students, (4) materials and facilities for training.\u0000\u0000Key words: satisfaction, medical students, university training, Hue University of Medicine and Pharmacy.","PeriodicalId":86274,"journal":{"name":"The South Dakota journal of medicine and pharmacy","volume":"33 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"74438495","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Assessment of knowledge, attitudes and practical skills in using inhalers for asthmatic outpatients","authors":"Phuong Vo Thi Hong, Anh Phan Dang Thuc, Ngoc Nguyen Phuoc Bich, Cuc Ngo Thi Kim, Quang Le Van, Hoa Phan Thi","doi":"10.34071/jmp.2023.2.18","DOIUrl":"https://doi.org/10.34071/jmp.2023.2.18","url":null,"abstract":"Background: Asthma is a chronic inflammatory disorder of the airways with increasing prevalence worldwide, becoming a burden for the healthcare system. Currently, inhaled therapy is the mainstay of asthma treatment. Factors associated with the incorrect use of inhalers were lack of knowledge or false beliefs. Incorrect inhalation techniques are the most common reasons that lead to uncontrolled asthma and treatment failure.\u0000\u0000Objectives: (1) To survey the knowledge and attitude of asthmatic outpatients towards asthma disease, treatment medicines and inhaler use. (2) To assess the patient’s practical skills in inhalation technique.\u0000\u0000Materials and methods: A descriptive cross-sectional study was conducted on asthmatic outpatients treated at Hue University of Medicine and Pharmacy hospital from March 2022 to April 2022.\u0000\u0000Results and conclusions: A total of 102 asthmatic patients were enrolled in the study. The proportion of males accounted for 62.7%. The mean age of patients was 59.2 ± 15.4. Regarding knowledge assessment, 31.4% of the patients had good knowledge of diseases and inhalers. Regarding that attitude, 24.5% of patients had a good attitude towards the disease and inhalers. The percentage of patients showing good practical skills in metered dose inhaler use (MDI) and dry powder inhaler (DPI) - Turbuhaler was 54.5%, DPI - Accuhaler was 66.7%.\u0000\u0000Key words: bronchial asthma, inhalers, metered dose inhaler, dry powder inhaler","PeriodicalId":86274,"journal":{"name":"The South Dakota journal of medicine and pharmacy","volume":"3 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"88432039","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Bone turnover markers reference database at University Medical Center, Ho Chi Minh city","authors":"Thanh Cao Ngoc, Thuy Tran Hong","doi":"10.34071/jmp.2023.2.13","DOIUrl":"https://doi.org/10.34071/jmp.2023.2.13","url":null,"abstract":"Objectives: To establish reference ranges for serum bone turnover markers including Osteocalcin (OC), Procollagen type 1 amino-terminal propeptide (P1NP), and Beta-CrossLaps (beta-CTX) in premenopausal women at University Medical Center, Ho Chi Minh City.\u0000\u0000Methods: A cross-sectional study was conducted on 157 women aged 20 to 44 years at University Medical Center, Ho Chi Minh City from December 2022 to February 2023. Demographic information, biochemical markers, and serum levels of OC, P1NP, and beta-CTX were recorded.\u0000\u0000Results: The mean serum levels of OC, P1NP, and beta-CTX were 15.57 ± 4.75 ng/mL, 41.98 ± 16.62 μg/L, and 314.03 ± 150.42 pg/mL, respectively. The levels of bone turnover markers varied significantly among different age groups (p < 0.01). Serum levels of OC, P1NP, and beta-CTX were negatively correlated with age, with r values of -0.44, -0.35 and -0.43 respectively (p < 0.01).\u0000\u0000Conclusion: The reference ranges for serum markers of bone turnover including OC, P1NP, and beta-CTX were 15.57 ± 4.75 ng/mL, 41.98 ± 16.62 μg/L, and 314.03 ± 150.42 pg/mL, respectively, in premenopausal women aged 20 to 44 years. Serum levels of OC, P1NP, and beta-CTX were negatively correlated with age in a moderate degree\u0000\u0000Key words: osteocalcin, P1NP, beta-CTX, bone turnover markers, premenopausal women.","PeriodicalId":86274,"journal":{"name":"The South Dakota journal of medicine and pharmacy","volume":"2 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"87465537","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Chemical composition and cytotoxic activity from n-hexane extract of Homalomena pendula","authors":"Linh Nguyen Khanh Thuy, Hoai Nguyen Thi, Anh Tran Thi Van, Duc Ho Viet","doi":"10.34071/jmp.2023.2.2","DOIUrl":"https://doi.org/10.34071/jmp.2023.2.2","url":null,"abstract":"Background and objectives: The genus Homalomena belongings to the Araceae family. Secondary metabolites afforded from this genus show various bioactivities. This study aimed to determine the chemical composition and cytotoxicl activities of compounds isolated from n-hexane extract of rhizomes of Homalomena pendula.\u0000\u0000Materials and methods: The rhizomes of Homalomena pendula were collected from Lam Dong, Vietnam in January 2021. Extraction methods included maceration, liquid-liquid and solidliquid partition. Isolation of pure compounds was carried out by a combination of various chromatographic methods. Chemical structures were determined by extensive spectroscopic methods. Evaluation of cytotoxic activity was performed by Skehan’s method.\u0000\u0000Results: 3 sesquiterpenoids (α-cadinol, homalomenol C, taiwaninone A) and 1 steroid (sitoindoside I) were isolated. α-cadinol inhibited SK-LU-1 and HEK-293A with IC50 of 97.75 ± 4.38 μM and 92.52 ± 2.80 μM, respectively. Sitoindoside I inhibited SK-LU-1, MCF7, Hep G2, 8505c and HEK-293A with IC50 of 44.05 ± 1.91 μM; 48.97 ± 3.93 μM; 60.64 ± 2.18 μM; 48.15 ± 5.51 μM and 57.22 ± 5.20 μM, respectively.\u0000\u0000Conclusion: This is the first report on the cytotoxic activity of compounds isolated from Homalomena pendula.\u0000\u0000Key words: Homalomena pendula, cytotoxic, α-cadinol, sitoindoside I.","PeriodicalId":86274,"journal":{"name":"The South Dakota journal of medicine and pharmacy","volume":"124 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"87950498","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The accuracy of clinical staging of stage I-IIIA non-small cell lung cancer by using thoracic computed tomography","authors":"Huu Hoang, Cuong Pham Hung","doi":"10.34071/jmp.2023.2.4","DOIUrl":"https://doi.org/10.34071/jmp.2023.2.4","url":null,"abstract":"Purpose: To assess the accuracy of clinical staging of stage I-IIIA non-small cell lung cancer (NSCLC) by using thoracic computed tomography (CT).\u0000\u0000Patients and Methods: Medical records of patients with NSCLC operated in two years 2018-2019 at Surgery Department No 2, HCMC Oncology Hospital were studied retrospectively.\u0000\u0000Results: Thoracic CT diagnosed tumor stage with an accuracy of 79% but failed to detect T3-4 disease in 8% of cases. Of nodal disease, thoracic CT had a diagnostic accuracy of 58% but misclassified N2 disease in 18% of cases. Agreement was poor between clinical and pathologic stage (Kappa coefficient= 0.186). Only 48% of patients was diagnosed accurately, and clinically understaged patients (45%) were more frequent than clinically overstaged one. Thoracic CT had a low sensitivity of only 19% in detecting stage IIIA disease, with 13 stage IIIA patients (21%) were missed diagnosis.\u0000\u0000Conclusion: Thoracic CT is not an ideal means for clinical staging of stage I-IIIA non-small cell lung cancer. To prevent the worsened outcomes associated with inaccurate staging, physicians should rely on established staging guidelines.\u0000\u0000Key words: non-small cell lung cancer, clinical staging, thoracic computed tomography","PeriodicalId":86274,"journal":{"name":"The South Dakota journal of medicine and pharmacy","volume":"10 2 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"90042485","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effect of Gynostemma pentaphyllum extract on spermatogenesis in heat stress-induced mice","authors":"Tung Nguyen Thanh, Quynh Nguyen Thi Khanh","doi":"10.34071/jmp.2023.2.10","DOIUrl":"https://doi.org/10.34071/jmp.2023.2.10","url":null,"abstract":"Background: Gynostemma pentaphyllum is a precious medicinal herb used in traditional medicines. Male reproductive dysfunction is caused by many factors, including heat stress. This study aimed to investigate the protective effect of Gynostemma pentaphyllum extract on spermatogenesis in heat stress-induced mice.\u0000\u0000Materials and Methods: Male mice were exposed at 40°C and treated with Gynostemma pentaphyllum extract at doses of 100, 200, and 400 mg/kg. After 5 weeks of treatment, blood samples were collected to determine the concentration of Testosterone in blood plasma. The histological structure of the seminiferous tubules was investigated through HE histological staining. The spermatogenesis progress was assessed using the Johnson scoring system.\u0000\u0000Results: Heat stress exposed at 40°C for 5 weeks has strongly reduced the concentration of testosterone in blood plasma as well as spermatogenesis in the lumen of the seminiferous tubules of testicular tissue. Heat stress-induced mice treated with oral administration of Gynostemma pentaphyllum extract significantly improved blood testosterone levels. Histological analysis and Johnson scoring show that the Gynostemma pentaphyllum extract significantly improved the spermatogenesis process in stress-induced mice that received the extract.\u0000\u0000Conclusions: Gynostemma pentaphyllum extract attenuates the impact of heat stress on spermatogenesis in male mice by improving blood testosterone levels and spermatogenesis in the seminiferous tubules.\u0000\u0000Key words: Gynostemma pentaphyllum, herbs, heat stress, spermatogenesis.","PeriodicalId":86274,"journal":{"name":"The South Dakota journal of medicine and pharmacy","volume":"100 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"73599674","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Evaluation of chronic apical periodontitis treatment results with Tricalcium silicate","authors":"Chi Phan Anh, Nga Le Thi Thu","doi":"10.34071/jmp.2023.2.3","DOIUrl":"https://doi.org/10.34071/jmp.2023.2.3","url":null,"abstract":"Background: Chronic apical periodontitis is potential infection with poor symptoms that are easily overlooked. Disease progession can lead to cellulitis, osteomyelitis, sinusitis, endocarditis, nephritis, arthritis, persistent fever and sepsis. In recent times, thanks to advances in endodontic in improving instruments, root canal antiseptics, techniques for shaping, obturation canals, endodontic treatment has achieved remarkable success rate. BioRootTM RCS is born from Active Biosilicate technology, is the lasted generation biomaterial, with the main ingredient being Tricalcium silicate and recommended for root canal obturation.\u0000\u0000Materials and Methods: 33 tooth with diagnosis of chronic apical periodontitis of 33 patients with inclusion criterias were selected in study sample, carried out endodontis treatment and obturation canals with BioRootTM RCS and cone Gutta Percha. Evaluating treatment results after 3 months, 6 months and factors associated with treatment results.\u0000\u0000Results: About treatment result after 3 months, 6 months: very good accounted for 87.9% and 90.9%, good were 12.1% and 9.1%, no poor cases; there was a relationship between the periapical index, lesion size, lesion boudaries with treatment results.\u0000\u0000Conclusion: BioRootTM RCS was a reliable material in the treatment of chronic apical periodontitis.\u0000\u0000Key words: Chronic apical periodontitis, Tricalcium Silicate, BioRootTM RC","PeriodicalId":86274,"journal":{"name":"The South Dakota journal of medicine and pharmacy","volume":"4 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"84222516","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Researching extended-view totally extraperitoneal (eTEP) approach for the treatment of inguinal hernia: two case reports","authors":"Phuc Nguyen Thanh, Vu Pham Anh","doi":"10.34071/jmp.2023.2.20","DOIUrl":"https://doi.org/10.34071/jmp.2023.2.20","url":null,"abstract":"Currently, mesh placement laparoscopic surgery is a first-line procedure for the repair of an inguinal hernia. Extended-view totally extraperitoneal (eTEP) technique for inguinal hernia repair has many advantages, such as the creation of an enlargement view, flexible port setup adaptability, and possible tolerance of pneumoperitoneum. Besides, it also repaired an incisional hernia. To contribute to the study and evaluation of the results of the eTEP technique for inguinal hernia repair, we reported the first two cases performed eTEP technique approach for the treatment of an inguinal hernia at our department: a 79-year-old male and a 62-year-old male referred to hospital for indirect inguinal hernia on the right side. Initial results were effective and safe. However, we need to research and follow up on the long-term outcomes to assess the advantages of this technique.\u0000Key words: inguinal hernia, inguinal hernia repair, Laparoscopic hernia repair, eTEP.","PeriodicalId":86274,"journal":{"name":"The South Dakota journal of medicine and pharmacy","volume":"54 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"85591500","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Soil-transmitted helminthes infection and related factors among primary school students at Ea Po commune, Cu Jut district, Dak Nong province","authors":"Thuy Tran Van, Trang Hoang Thi Minh, Phuong Ngo Van, Nhung Nguyen Thi Cam","doi":"10.34071/jmp.2023.2.16","DOIUrl":"https://doi.org/10.34071/jmp.2023.2.16","url":null,"abstract":"Background: Soil-transmitted helminth infection is a common and a significant health problem in poor and developing countries. Children are the most commonly infected with soil-transmitted helminths.\u0000\u0000Objectives: To determine the proportion of soil-transmitted helminth and related factors to soil-transmitted helminth infection in primary school students in Ea Po commune, Cu Jut district, Dak Nong province, in 2021.\u0000\u0000Material and methods: A cross-sectional study was caried out on 440 primary school students attending two primary schools. Participants were interviewed and collected the fecal to detect soil-transmitted helminths by the Kato technique.\u0000\u0000Results: The prevalence of soil-transmitted helminth infection among primary school students was 17.5%. Ethnicity, hand washing before eating, barefoot walking, and toilet were related factors to soil-transmitted helminth infection.\u0000\u0000Conclusion: These results reinforce the need to take more effective actions to address soil-transmitted helminth infection in children.\u0000\u0000Key words: prevalence, related factors, soil-transmitted helminths.","PeriodicalId":86274,"journal":{"name":"The South Dakota journal of medicine and pharmacy","volume":"24 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"73837965","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Factors associated with mortality among extremely preterm infants at Da Nang Hospital for Women and Children","authors":"Hoang Yen Tran Thi, Thuy Pham Thi Nhu","doi":"10.34071/jmp.2023.2.6","DOIUrl":"https://doi.org/10.34071/jmp.2023.2.6","url":null,"abstract":"Introduction: Management of extremely preterm infants under 28 weeks of gestation remains a challenge for neonatal care. This study was carried out to describe morbidity and mortality rates of extremely preterm infants and to investigate factors associated with mortality in this group.\u0000\u0000Methods: A longitudinal study was conducted from admission to discharge or death on 102 extremely preterm infants under 28 weeks of gestation who were managed at the Neonatal Unit, Da Nang Hospital for Women and Children from May 1, 2020 to May 30, 2022.\u0000\u0000Result: The mean gestational age was 25.5 weeks with an average weight of 815.2 grams. Respiratory distress syndrome requiring surfactant occurred in 58.8%. Intraventricular haemorrahage grade III-IV occurred in 14.7% and necrotizing enterocolitis in 6.9%. The mortality rate was 49%, with 70% among infants < 26 weeks of gestation, and 28.8% in infants 26 - < 28 weeks of gestation. Gestational age, shock, and invasive mechanical ventilation were associated with mortality in extremely preterm neonates. Every 1 week increase in gestational age reduced the risk of death by 2.5 times. Shock and invasive mechanical ventilation increased the risk of death with Odds ratios being 17.7 and 49.9, respectively.\u0000\u0000Conclusion: Mortality and morbidity among extremely preterm neonates were high. Future interventions should focus on preventing complications and improving suboptimal care.\u0000\u0000Key words: extremely preterm infant, neonatal mortality, neonatal intensive care.","PeriodicalId":86274,"journal":{"name":"The South Dakota journal of medicine and pharmacy","volume":"64 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"80331616","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}