Asia-Pacific Journal of Ophthalmology最新文献

{"title":"Response: Comment on \"Update on coronavirus disease 2019: Ophthalmic manifestations and adverse reactions to vaccination\"","authors":"Timothy P.H. Lin","doi":"10.1016/j.apjo.2024.100083","DOIUrl":"10.1016/j.apjo.2024.100083","url":null,"abstract":"","PeriodicalId":8594,"journal":{"name":"Asia-Pacific Journal of Ophthalmology","volume":"13 4","pages":"Article 100083"},"PeriodicalIF":3.7,"publicationDate":"2024-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2162098924000847/pdfft?md5=6bdc129df9908045303c1dd36cf331d4&pid=1-s2.0-S2162098924000847-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141747347","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Deep Learning‐Enabled Vasculometry Depicts Phased Lesion Patterns in High Myopia Progression","authors":"Hai-Long He ,&nbsp;Yi-Xin Liu ,&nbsp;Hanruo Liu ,&nbsp;Xiaomei Zhang ,&nbsp;Hao Song ,&nbsp;Tian-Ze Xu ,&nbsp;Yuxin Fang ,&nbsp;Ya Ma ,&nbsp;Hao-Ying Ren ,&nbsp;Sai-Guang Ling ,&nbsp;Zhou Dong ,&nbsp;Jie Xu ,&nbsp;Lei Qin ,&nbsp;Tien Yin Wong ,&nbsp;Marcus Ang ,&nbsp;Zi-Bing Jin","doi":"10.1016/j.apjo.2024.100086","DOIUrl":"10.1016/j.apjo.2024.100086","url":null,"abstract":"<div><h3>Purpose</h3><p>To investigate the potential phases in myopic retinal vascular alterations for further elucidating the mechanisms underlying the progression of high myopia (HM).</p></div><div><h3>Methods</h3><p>For this retrospective study, participants diagnosed with high myopia at Beijing Tongren Hospital were recruited. Based on bionic mechanisms of human vision, an intelligent image processing model was developed and utilized to extract and quantify the morphological characteristics of retinal vasculatures in different regions measured by papilla-diameter (PD), including vascular caliber, arteriole-to-venule ratio (AVR), tortuosity, the angle of the vascular arch (AVA), the distance of the vascular arch (DVA), density, fractal dimension, and venular length. In addition, the optic disc and the area of peripapillary atrophy (PPA) were also quantified. The characteristics of the overall population, as well as patients aged less than 25 years old, were compared by different genders. Univariate and multiple linear regression analyses were conducted to investigate the correlation of retinal vasculature parameters with PPA width, and detailed trends of the vascular indicators were analyzed to explore the potential existence of staged morphological changes.</p></div><div><h3>Findings</h3><p>The study included 14,066 fundus photographs of 5775 patients (aged 41.2 ± 18.6 years), of whom 7379 (61.2 %) were female. The study included 12,067 fundus photographs of 5320 patients (aged 41.2 ± 18.6 years). Significant variations in the morphological parameters of retinal vessels were observed between males and females. After adjusting for age and sex, multiple linear regression analysis showed that an increased PPA width ratio was associated with lower AVA (1PD), DVA (1PD), vascular caliber (0.5–1.0 PD), tortuosity (0.5–1.0 PD), density and fractal dimension (all P &lt; 0.001, Spearman’s ρ &lt; 0). Overall, the changes in retinal vascular morphology showed two phases: tortuosity (0.5–1.0PD) and AVA (1PD) decreased rapidly in the first stage but significantly more slowly in the second stage, while vascular density and fractal dimension showed a completely opposite trend with an initial slow decline followed by a rapid decrease.</p></div><div><h3>Conclusions</h3><p>This study identified two distinct phases of retinal vascular morphological changes during the progression of HM. Traction lesions were predominant in the initial stage, while atrophic lesions were predominant in the later stage. These findings provide further insight into the development mechanism of HM from the perspective of retinal vasculature.</p></div>","PeriodicalId":8594,"journal":{"name":"Asia-Pacific Journal of Ophthalmology","volume":"13 4","pages":"Article 100086"},"PeriodicalIF":3.7,"publicationDate":"2024-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2162098924000872/pdfft?md5=cbe2792816086903d279eb12d98f67f8&pid=1-s2.0-S2162098924000872-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141756833","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Response to Letter to the Editor: “Discrepancies in reported prevalence rates of keratoconus in Russia”","authors":"Mukharram M. Bikbov ,&nbsp;Gyulli M. Kazakbaeva ,&nbsp;Timur R. Gilmanshin ,&nbsp;Ellina M. Iakupova ,&nbsp;Albina A. Fakhretdinova ,&nbsp;Azaliia M. Tuliakova ,&nbsp;Songhomitra Panda-Jonas ,&nbsp;Iuliia A. Rusakova ,&nbsp;Leisan I. Gilemzianova ,&nbsp;Dinar A. Khakimov ,&nbsp;Liana A. Miniazeva ,&nbsp;Emin L. Usubov ,&nbsp;Jost B. Jonas","doi":"10.1016/j.apjo.2024.100078","DOIUrl":"10.1016/j.apjo.2024.100078","url":null,"abstract":"","PeriodicalId":8594,"journal":{"name":"Asia-Pacific Journal of Ophthalmology","volume":"13 3","pages":"Article 100078"},"PeriodicalIF":4.4,"publicationDate":"2024-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2162098924000793/pdfft?md5=0595cb12b080eadc9198559173b3fe8d&pid=1-s2.0-S2162098924000793-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141154881","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Immediate versus delayed sequential bilateral ICL implantation: A retrospective comparison of vault height and visual outcomes","authors":"Yinjie Jiang ,&nbsp;Xun Chen ,&nbsp;Mingrui Cheng ,&nbsp;Boliang Li ,&nbsp;Yadi Lei ,&nbsp;I-Chun Lin ,&nbsp;Guanghan Xu ,&nbsp;Li Mingwei ,&nbsp;Xingtao Zhou ,&nbsp;Xiaoying Wang","doi":"10.1016/j.apjo.2024.100075","DOIUrl":"10.1016/j.apjo.2024.100075","url":null,"abstract":"<div><h3>Purpose</h3><p>To compare the visual outcomes and risks of suboptimal vault-related complications between immediate sequential bilateral ICL surgery (ISBICLS) and delayed sequential bilateral ICL surgery (DSBICLS).</p></div><div><h3>Design</h3><p>A retrospective cohort study.</p></div><div><h3>Methods</h3><p>Patients who underwent bilateral ICL implantation between November 2014 and December 2021 at the Eye and ENT Hospital of Fudan University (Shanghai, China) were included and divided into two groups: (1) ISBICLS: both eye surgeries performed on the same day, and (2) DSBICLS: second eye surgery performed &lt; 7 days following the first one. Propensity score matching (PSM) was performed to compare the visual outcomes. Multivariable logistic regression models were used to estimate the odds ratios (ORs) of the suboptimal vaults.</p></div><div><h3>Results</h3><p>Finally, 10,985 eyes were included. After PSM, 204 first surgery eyes and 162 s surgery eyes with complete postoperative data were matched. The safety and efficacy indices did not statistically differ between groups (all &gt; 1.00), except that ISBICLS first surgery eyes achieved better efficacy index than DSBICLS group (1.03 ± 0.26 vs. 1.08 ± 0.23, <em>P</em> = 0.034). Excessive vault was observed in eight (4.06 %) ISBICLS first eyes, one (0.50 %) DSBICLS first eye, and none in the second surgery eye in either group. An insufficient vault was observed in one second eye and one DSBICLS second eye. We found no evidence of differences in the rate of excessive vault (OR = 0.831, 95 % CI: 0.426–1.622, <em>P</em> = 0.588) or insufficient vault (OR = 0.609, 95 % CI:0.062–5.850, <em>P</em> = 0.668).</p></div><div><h3>Conclusion</h3><p>ISBICLS provided safety, efficacy, and refraction predictability comparable to DSBICLS without increasing the risk of suboptimal vault-related complications.</p></div>","PeriodicalId":8594,"journal":{"name":"Asia-Pacific Journal of Ophthalmology","volume":"13 3","pages":"Article 100075"},"PeriodicalIF":4.4,"publicationDate":"2024-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2162098924000768/pdfft?md5=94e38baf1a68bfcb3c409a84c7684fc4&pid=1-s2.0-S2162098924000768-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141137391","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Exaggerated immune response to fungal keratitis post-COVID-19 vaccination","authors":"Isana Nakajima,&nbsp;Ken Fukuda,&nbsp;Tamaki Sumi,&nbsp;Kenji Yamashiro","doi":"10.1016/j.apjo.2024.100063","DOIUrl":"10.1016/j.apjo.2024.100063","url":null,"abstract":"","PeriodicalId":8594,"journal":{"name":"Asia-Pacific Journal of Ophthalmology","volume":"13 3","pages":"Article 100063"},"PeriodicalIF":4.4,"publicationDate":"2024-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2162098924000586/pdfft?md5=0787111ba15b04d8bde508f7995cc33e&pid=1-s2.0-S2162098924000586-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140852801","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Concealed retro-iridic multi-cavitary melanoma revealed by ultrasound biomicroscopy","authors":"Miguel E. Hernandez-Emanuelli,&nbsp;Rolika Bansal,&nbsp;Thomas M. Catapano,&nbsp;Carol L. Shields","doi":"10.1016/j.apjo.2024.100049","DOIUrl":"10.1016/j.apjo.2024.100049","url":null,"abstract":"","PeriodicalId":8594,"journal":{"name":"Asia-Pacific Journal of Ophthalmology","volume":"13 3","pages":"Article 100049"},"PeriodicalIF":4.4,"publicationDate":"2024-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2162098924000446/pdfft?md5=77e7d2e15a66e9202e418edc3df804fd&pid=1-s2.0-S2162098924000446-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140179283","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Comment on “Phacogoniotomy versus phacotrabeculectomy for advanced primary angle-closure glaucoma with cataract: A randomized non-inferiority trial”","authors":"P. Connor Lentz ,&nbsp;Leticia Checo ,&nbsp;Isabella V. Wagner ,&nbsp;Nithya Boopathiraj ,&nbsp;Emily Dorairaj ,&nbsp;Syril Dorairaj","doi":"10.1016/j.apjo.2024.100066","DOIUrl":"10.1016/j.apjo.2024.100066","url":null,"abstract":"","PeriodicalId":8594,"journal":{"name":"Asia-Pacific Journal of Ophthalmology","volume":"13 3","pages":"Article 100066"},"PeriodicalIF":4.4,"publicationDate":"2024-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2162098924000677/pdfft?md5=22fcc65ad88d1bc96745c0cb9cad5d80&pid=1-s2.0-S2162098924000677-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140891262","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Cost-effectiveness of diabetic retinopathy screening for newly diagnosed type 2 diabetic patients: A nationwide population-based propensity score-matched cohort study","authors":"Yu-Chien Chung ,&nbsp;Yi-Wei Kao ,&nbsp;Yen-Chun Huang ,&nbsp;Pei-En Chen ,&nbsp;Shu-Chen Liao ,&nbsp;Chih-Kuang Liu ,&nbsp;Mingchih Chen","doi":"10.1016/j.apjo.2024.100071","DOIUrl":"10.1016/j.apjo.2024.100071","url":null,"abstract":"<div><h3>Aims</h3><p>This study investigated the association between the frequency of screening for diabetic retinopathy (DR) versus the development of DR and corresponding medical expenses among patients newly diagnosed with type 2 diabetes mellitus (T2DM).</p></div><div><h3>Methods</h3><p>This longitudinal, population-based study used the Taiwan National Health Insurance Research Database (2004 to 2020) as a data source. Propensity score matching (PSM) (sex, age, comorbidities and concurrent medication use) was employed in the grouping of T2DM patients according to different frequency of DR screening. Outcome measures included the proportion of patients who developed DR, who received DR treatment, and the associated medical expenses and hospitalizations.</p></div><div><h3>Results</h3><p>The 17-year cohort included 337,046 patients. After PSM, three groups each containing 35,739 patients were assembled and analyzed. Compared to low-frequency screening, high-frequency screening was more effective in detecting patients requiring treatment; however, the net cost for treatment was significantly lower. Standard-frequency screening appears to provide the best balance in terms of DR detection, diagnosis interval, the risk of DR-related hospitalization, and DR treatment costs.</p></div><div><h3>Conclusions</h3><p>In this real-world cohort study covering all levels of the healthcare system, infrequent screening was associated with delayed diagnosis and elevated treatment costs, while a fundus screening interval of 1–2 years proved optimal in terms of detection and medical expenditures.</p></div>","PeriodicalId":8594,"journal":{"name":"Asia-Pacific Journal of Ophthalmology","volume":"13 3","pages":"Article 100071"},"PeriodicalIF":4.4,"publicationDate":"2024-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2162098924000720/pdfft?md5=5325c510e97d01d39654289e634f6601&pid=1-s2.0-S2162098924000720-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141070410","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Long-term efficacy and safety of posterior endoscopic cyclophotocoagulation in refractory glaucoma: A 5-year follow-up study at a tertiary eye center","authors":"Yuxin Fang,&nbsp;Pengfei Zheng,&nbsp;Xin Tang,&nbsp;Qiyan Li","doi":"10.1016/j.apjo.2024.100074","DOIUrl":"10.1016/j.apjo.2024.100074","url":null,"abstract":"<div><h3>Purpose</h3><p>To evaluate the long-term efficacy of endoscopic cyclophotocoagulation (ECP) via a pars plana approach in a large cohort of refractory glaucoma patients</p></div><div><h3>Design</h3><p>Single-center, retrospective, longitudinal, cohort study.</p></div><div><h3>Methods</h3><p>This study recruited patients who underwent ECP and consecutively visited and were followed up for at least 5 years at Beijing Tongren Eye Center, China from January 2013 to December 2017. All patients underwent a complete ophthalmic examination. Treatment success was defined as 6 mmHg ≤ IOP ≤ 21 mmHg with or without anti-glaucoma medications.</p></div><div><h3>Results</h3><p>A total of 121 eyes of 105 patients including 51 children and 54 adults were enrolled. The mean follow-up was 7.2 ± 1.3 years. The most common glaucoma diagnoses were secondary glaucoma (74 eyes, 61.1 %) and primary congenital glaucoma (19 eyes 15.7 %). The mean extent of the first ECP was 259 degrees. There was an overall decrease in IOP of 38.3 % from 33.3 ± 9.0 mmHg preoperatively to 20.5 ± 7.5 mmHg after surgery, which was statistically significant (<em>P</em> &lt; 0.001). The success rate after 1 or more ECP surgery was 65.3 %. After adjusting for sex, number of prior TCP surgeries and the extent of ECP degree, the failure of ECP was associated with being children (as compared with adults; <em>P</em> = 0.028; OR = 2.549) and higher preoperative IOP (<em>P</em> = 0.001; OR = 1.084).</p></div><div><h3>Conclusion</h3><p>ECP is an effective procedure for lowing IOP in refractory glaucoma, particularly in patients who are also candidates for vitreoretinal interventions. Hence, a collaborative approach between glaucoma and retinal specialists is of utmost importance in devising an optimal management strategy for glaucoma treatment.</p></div>","PeriodicalId":8594,"journal":{"name":"Asia-Pacific Journal of Ophthalmology","volume":"13 3","pages":"Article 100074"},"PeriodicalIF":4.4,"publicationDate":"2024-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2162098924000756/pdfft?md5=1d44ec0d02ae6453c527f61ddaf415d8&pid=1-s2.0-S2162098924000756-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141144157","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Risk factors for diabetic retinopathy, diabetic macular edema, and sight-threatening diabetic retinopathy","authors":"Guihua Zhang ,&nbsp;Weiqi Chen ,&nbsp;Haoyu Chen ,&nbsp;Jianwei Lin ,&nbsp;Ling-Ping Cen ,&nbsp;Peiwen Xie ,&nbsp;Yi Zheng ,&nbsp;Tsz Kin Ng ,&nbsp;Mårten Erik Brelén ,&nbsp;Mingzhi Zhang ,&nbsp;Chi Pui Pang","doi":"10.1016/j.apjo.2024.100067","DOIUrl":"10.1016/j.apjo.2024.100067","url":null,"abstract":"<div><h3>Objective</h3><p>To identify the risk factors for the development of diabetic retinopathy (DR), diabetic macular edema (DME), and sight-threatening DR (STDR) based on a city-wide diabetes screening program.</p></div><div><h3>Research design and methods</h3><p>Diabetic patients were prospectively recruited between June 2016 and December 2022. All patients underwent dilated fundus photography centered on the disc and macula or macular spectral domain optical coherence tomography (SD-OCT) scan. Complete medical history was documented. Systematic examination, blood analysis, and urinalysis were performed. Multivariate logistic regression analysis adjusting for age and sex was conducted.</p></div><div><h3>Results</h3><p>Out of 7274 diabetic patients, 6840 had gradable images, among which 3054 (42.0%) were graded as DR, 1153 (15.9%) as DME, and 1500 (20.6%) as STDR. The factors associated with DR, DME, and STDR included younger age (odds ratio [OR]: 0.96, 0.97, and 0.96 respectively), lower BMI (OR: 0.97, 0.95, and 0.95 respectively), longer duration of diabetes (OR: 1.07, 1.03, and 1.05 respectively) and positive of urinary albumin (OR: 2.22, 2.56, and 2.88 respectively). Other associated factors included elevated blood urea nitrogen (OR: 1.22, 1.28, and 1.27 respectively), higher LDL-cholesterol, lower blood hemoglobin (OR: 0.98, 0.98, and 0.98), insulin intake, presence of diabetic foot pathologies and diabetic peripheral neuropathy. We also identified novel risk factors, including high serum potassium (OR: 1.37, 1.46, and 1.55 respectively), high-serum sodium (OR: 1.02, 1.02, and 1.04 respectively). Better family income was a protective factor for DR, DME, and STDR. Alcohol consumption once a week was also identified as a protective factor for DR.</p></div><div><h3>Conclusions</h3><p>Similar risk factors for DR, DME, and STDR were found in this study. Our data also indicates high serum sodium, high serum potassium, low blood hemoglobin, and level of family income as novel associated factors for DR, DME, and STDR, which can help with DR monitoring and management.</p></div>","PeriodicalId":8594,"journal":{"name":"Asia-Pacific Journal of Ophthalmology","volume":"13 3","pages":"Article 100067"},"PeriodicalIF":4.4,"publicationDate":"2024-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2162098924000689/pdfft?md5=d2a990b0030a8bf37cf5bb7507b10252&pid=1-s2.0-S2162098924000689-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140943293","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}