Wiktor Stopyra , Oleksiy Voytsekhivskyy , Andrzej Grzybowski
{"title":"Comparison of the accuracy of twenty intraocular lens power calculation formulas in long eyes","authors":"Wiktor Stopyra , Oleksiy Voytsekhivskyy , Andrzej Grzybowski","doi":"10.1016/j.apjo.2025.100198","DOIUrl":"10.1016/j.apjo.2025.100198","url":null,"abstract":"<div><h3>Purpose</h3><div>To compare the accuracy of twenty intraocular lens (IOL) power calculation formulas in long eyes (26.00–29.99 mm)</div></div><div><h3>Design</h3><div>Retrospective accuracy and validity analysis</div></div><div><h3>Methods</h3><div>The data of patients who underwent uneventful phacoemulsification between August 2019 and July 2024 were reviewed. Pre-surgery IOL power was calculated using Haigis, Holladay 2, SRK/T and Barrett Universal II formulas. Three months after cataract surgery, refraction was measured. Post-surgery IOL power calculations were performed utilizing the following formulas: Castrop, EVO 2.0, Hill-RBF 3.0, Hoffer Q, Holladay 1, Hoffer QST, K6, Kane, Karmona, Ladas Super Formula AI (LSF AI), Naeser 2, Olsen (standalone), PEARL-DGS, T2, VRF and VRF-G. Root mean square absolute error (RMSAE), median absolute error (MedAE) and percentage of eyes with prediction error (PE) within ± 0.25 D, ± 0.50 D, ± 0.75 D and ± 1.00 were calculated.</div></div><div><h3>Results</h3><div>One hundred fifty-three eyes with axial length ranging between 26.00 mm and 29.47 mm, were studied. The SRK/T formula yielded the lowest RMSAE (0.349) with statistical superiority over Holladay 1 (0.519, <em>P</em> = 0.000), Olsen (standalone) (0.505, <em>P</em> = 0.000) and Hoffer Q (0.497, <em>P</em> = 0.000). In terms of MedAE, the lowest outcome was obtained by VRF-G (0.256) followed by Barrett Universal II, Hill-RBF 3.0 and LSF AI (all equally of 0.260). The highest percentage of eyes with prediction error within ± 0.50 D was achieved by SRK/T (84.97 %) statistically significant vs Holladay 1 (60.78 %), Hoffer Q (64.05 %) and Olsen(standalone) (68.63 %).</div></div><div><h3>Conclusions</h3><div>SRK/T has delivered highly accurate results in long eyes. Barrett Universal II, Hill-RBF 3.0, VRF-G and LSF AI are also very true.</div></div>","PeriodicalId":8594,"journal":{"name":"Asia-Pacific Journal of Ophthalmology","volume":"14 3","pages":"Article 100198"},"PeriodicalIF":3.7,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143961782","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Francesca Corsi , Alessia Galante , Maria Anna Maggi , Raffaele Mazziotti , Silvia Bisti , Ilaria Piano , Claudia Gargini
{"title":"The efficacy of Saffron Repron® in counteracting the progression of retinitis pigmentosa: Neuroprotection and resilience","authors":"Francesca Corsi , Alessia Galante , Maria Anna Maggi , Raffaele Mazziotti , Silvia Bisti , Ilaria Piano , Claudia Gargini","doi":"10.1016/j.apjo.2025.100192","DOIUrl":"10.1016/j.apjo.2025.100192","url":null,"abstract":"<div><div>The mutations observed in the various forms of retinitis pigmentosa (RP) affect genes coding for rod-specific proteins and direct the progression of different forms of dystrophy toward total blindness. The present investigation aims to explore the protective effects of Saffron Repron®, in a mouse model of RP. Saffron was administered orally to pregnant females and weaned pups for 120 days. At different time points (P30, P60, P90, and P120), visual function, retinal function, cone lifespan, morphology, gene expression, and protein level were analyzed. The results indicate that chronic saffron treatment effectively slows the progression of long-term damage caused by genetic mutations in both the morphology and function of retinal neurons. Cellular mechanisms responsible for this action appear complex and, probably, due to coordinated and synergistic activities by its chemical components. Here we provide evidence that saffron is able to modulate the epigenetic pathway involved in neuroinflammation. Biochemical and molecular measures suggest that early saffron treatment may induce a form of adaptation known as acquired resilience.</div></div>","PeriodicalId":8594,"journal":{"name":"Asia-Pacific Journal of Ophthalmology","volume":"14 3","pages":"Article 100192"},"PeriodicalIF":3.7,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143690970","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Andrea Chor Kiu Au , Daniel Ho Tak Wong , Kenneth Kai Wang Li
{"title":"Updates on the clinical management of intraocular foreign body (IOFB)","authors":"Andrea Chor Kiu Au , Daniel Ho Tak Wong , Kenneth Kai Wang Li","doi":"10.1016/j.apjo.2025.100208","DOIUrl":"10.1016/j.apjo.2025.100208","url":null,"abstract":"<div><div>This review aims to summarise recent literature in the past decade, focusing on new insights, management strategies, and technique modifications for intraocular foreign body (IOFB) cases. We discuss the latest epidemiological data, diagnostic assessments, and challenging presentations of IOFB. Imaging, particularly non-contrast helical computed tomography with thin cuts, is a valuable diagnostic adjunct. The administration of perioperative prophylactic systemic and intravitreal antibiotics may be useful in reducing infective endophthalmitis risk. We recommend same stage IOFB removal with primary repair within 24 hours whenever feasible. Furthermore, the latest updates on surgical planning, techniques, and instrumentation for IOFB removal, including crystalline lens management, IOFB extraction routes, and intraoperative adjuncts such as perfluorocarbon liquid, cohesive viscoelastic, and mitomycin-C are described. Various IOFB removal techniques including magnet-based, scaffold, suture-based, aspiration and bimanual methods, specialised and innovative instruments are also discussed. This review compiles the most recent advancements and techniques, offering a comprehensive update on the clinical management and surgical removal of IOFB.</div></div>","PeriodicalId":8594,"journal":{"name":"Asia-Pacific Journal of Ophthalmology","volume":"14 3","pages":"Article 100208"},"PeriodicalIF":3.7,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144118705","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Vision impairment-related burden of disease","authors":"Jost B. Jonas","doi":"10.1016/j.apjo.2025.100203","DOIUrl":"10.1016/j.apjo.2025.100203","url":null,"abstract":"","PeriodicalId":8594,"journal":{"name":"Asia-Pacific Journal of Ophthalmology","volume":"14 3","pages":"Article 100203"},"PeriodicalIF":3.7,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143970268","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Vacuum evaporation in the vitreous cavity.","authors":"Alexander Jessup, Andrew Chang","doi":"10.1016/j.apjo.2025.100201","DOIUrl":"10.1016/j.apjo.2025.100201","url":null,"abstract":"","PeriodicalId":8594,"journal":{"name":"Asia-Pacific Journal of Ophthalmology","volume":" ","pages":"100201"},"PeriodicalIF":3.7,"publicationDate":"2025-04-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143967289","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"A rare case of caruncular actinomycosis presenting with tumor-like features.","authors":"Tatsuya Sakamoto, Kentaro Sueoka, Taiichiro Chikama","doi":"10.1016/j.apjo.2025.100202","DOIUrl":"https://doi.org/10.1016/j.apjo.2025.100202","url":null,"abstract":"","PeriodicalId":8594,"journal":{"name":"Asia-Pacific Journal of Ophthalmology","volume":" ","pages":"100202"},"PeriodicalIF":3.7,"publicationDate":"2025-04-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143967287","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Ryan B Rush, Pedro Luis Gomez, Pedro Gomez Bastar, Sloan W Rush
{"title":"Panretinal photocoagulation during vitrectomy for diabetic vitreous hemorrhage: A clinical trial comparing endolaser application amounts.","authors":"Ryan B Rush, Pedro Luis Gomez, Pedro Gomez Bastar, Sloan W Rush","doi":"10.1016/j.apjo.2025.100197","DOIUrl":"https://doi.org/10.1016/j.apjo.2025.100197","url":null,"abstract":"<p><strong>Purpose: </strong>To evaluate the effectiveness of different endolaser photocoagulation treatment amounts during pars plana vitrectomy (PPV) in patients with a vitreous hemorrhage (VH) secondary to proliferative diabetic retinopathy (PDR).</p><p><strong>Design: </strong>Randomized clinical trial METHODS: One hundred and forty-four treatment-naïve PDR patients with an ocular media-obscuring VH were enrolled into this clinical trial. Participants were randomized into one of two possible treatment groups: Group A subjects underwent PPV and received 250 + /- 50 endolaser applications during surgery, while Group B subjects underwent PPV and received 550 + /- 50 endolaser applications during surgery. The primary outcome was the rate of postoperative VH, and the secondary outcome was visual acuity at 6 months.</p><p><strong>Results: </strong>Ninety-one patients underwent PPV and completed the 6-month trial period. Group A had 30.0 % (15/50) of participants develop a postoperative VH, while Group B had 12.2 % (5/41) of subjects develop a postoperative VH at 6 months (P = 0.002). The visual acuity of 0.4 (0.23-0.57) logMAR (Snellen 20/50) in Group B was better than that of 0.79 (0.58-1.01) logMAR (Snellen 20/120) in Group A at the end of the 6 month trial period (P = 0.006).</p><p><strong>Conclusions: </strong>Treatment-naïve PDR subjects undergoing PPV for an ocular media-obscuring VH have a lower incidence of postoperative VH and better visual acuity at 6 months when 550 + /- 50 endolaser applications were administered compared to 250 + /- 50 endolaser applications during PPV. Further research is warranted on this topic to verify the generalizability of these findings to a broader PDR population.</p>","PeriodicalId":8594,"journal":{"name":"Asia-Pacific Journal of Ophthalmology","volume":" ","pages":"100197"},"PeriodicalIF":3.7,"publicationDate":"2025-04-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143955329","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Barriers to MIGS adoption among glaucoma specialists in India: Insights from a targeted survey.","authors":"Sahebaan Sethi, Shweta Tripathi, Maneesh Singh, Nagalekshmi Ganesh, Mayav Movdawalla, Shahinur Tayab","doi":"10.1016/j.apjo.2025.100195","DOIUrl":"10.1016/j.apjo.2025.100195","url":null,"abstract":"","PeriodicalId":8594,"journal":{"name":"Asia-Pacific Journal of Ophthalmology","volume":" ","pages":"100195"},"PeriodicalIF":3.7,"publicationDate":"2025-04-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143794570","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Joanna Ng, Nazli Gul, Arjun Shrestha, Hong Kee Ng, Raymond N Regalado, Rachel S Chong
{"title":"Flourishing index measures among ophthalmologists in the Asia-Pacific region.","authors":"Joanna Ng, Nazli Gul, Arjun Shrestha, Hong Kee Ng, Raymond N Regalado, Rachel S Chong","doi":"10.1016/j.apjo.2025.100193","DOIUrl":"10.1016/j.apjo.2025.100193","url":null,"abstract":"","PeriodicalId":8594,"journal":{"name":"Asia-Pacific Journal of Ophthalmology","volume":" ","pages":"100193"},"PeriodicalIF":3.7,"publicationDate":"2025-03-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143750363","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}