Asia-Pacific Journal of Ophthalmology最新文献

Changes in choroidal thickness in pre-myopic children after repeated low-level red-light therapy and their role in predicting myopia prevention and controlling myopic shift.

IF 3.7 3区医学

Asia-Pacific Journal of Ophthalmology Pub Date : 2024-12-01 DOI: 10.1016/j.apjo.2024.100115

Kaidi Xiang, Jingjing Wang, Zhuoting Zhu, Xinzi Zhang, Bo Zhang, Jun Chen, Jinliuxing Yang, Linlin Du, Zhijian Ai, Xiangui He, Xun Xu

{"title":"Changes in choroidal thickness in pre-myopic children after repeated low-level red-light therapy and their role in predicting myopia prevention and controlling myopic shift.","authors":"Kaidi Xiang, Jingjing Wang, Zhuoting Zhu, Xinzi Zhang, Bo Zhang, Jun Chen, Jinliuxing Yang, Linlin Du, Zhijian Ai, Xiangui He, Xun Xu","doi":"10.1016/j.apjo.2024.100115","DOIUrl":"10.1016/j.apjo.2024.100115","url":null,"abstract":"Purpose: To investigate longitudinal changes in choroidal thickness (ChT) after 1-year treatment of repeated low-level red-light (RLRL) and their predictive value in efficacy on myopia prevention and myopic shift among pre-myopic children.Methods: 278 pre-myopic (-0.50 D < spherical equivalent refraction, SER ≤ 0.50 D) participants were assigned to the RLRL group and control group randomly and evenly. The OCT, visual acuity, AL, SER and other parameters were measured before enrollment and every 3 months after intervention. The data from both eyes of the included participants were analyzed.Results: A total of 463 eyes were analyzed. Due to the COVID-19 pandemic, 176 participants in the RLRL group had treatment interrupted. The continued RLRL group, interrupted RLRL group and control group were well balanced in baseline characteristics. In the continued and interrupted RLRL group, the average ChT increased significantly at 3-month visit (all P < 0.001) and the subfoveal ChT thickened evidently. The area under the curve (AUC) for the models including gender and 3-month change in ChT to predict satisfactory myopia prevention at 12 months was 0.983. The efficacy of the models that also used the combined indicators of baseline age, gender and the 3-month change in ChT to predict AL progression control over 12 months reached 0.944.Conclusions: Continued RLRL intervention induced notable thickening of ChT in premyopic population, especially at the subfoveal sector. For participants received RLRL treatment, the 3-month change in ChT combined with other baseline factors have acceptable predictive discrimination of myopia prevention efficacy.","PeriodicalId":8594,"journal":{"name":"Asia-Pacific Journal of Ophthalmology","volume":" ","pages":"100115"},"PeriodicalIF":3.7,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142765660","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Rapid-onset central retinal vein occlusion following inactivated COVID-19 vaccination.

IF 3.7 3区医学

Asia-Pacific Journal of Ophthalmology Pub Date : 2024-11-01 Epub Date: 2024-12-06 DOI: 10.1016/j.apjo.2024.100118

Yuchen Zhang, Hao Zhou, Suqin Yu, Chong Chen

引用次数: 0

Axial elongation in nonpathologic high myopia: Ocular structural changes and glaucoma diagnostic challenges.

IF 3.7 3区医学

Asia-Pacific Journal of Ophthalmology Pub Date : 2024-11-01 Epub Date: 2024-12-16 DOI: 10.1016/j.apjo.2024.100123

Kangjie Kong, Xiaoyi Liu, Zige Fang, Jingwen Jiang, Jiaxuan Jiang, Deming Wang, Zefeng Yang, Fengqi Zhou, Evan M Chen, Jill Liang, Yunhe Song, Fengbin Lin, Kyoko Ohno-Matsui, Jost B Jonas, Ying Han, Fei Li, Xiulan Zhang

{"title":"Axial elongation in nonpathologic high myopia: Ocular structural changes and glaucoma diagnostic challenges.","authors":"Kangjie Kong, Xiaoyi Liu, Zige Fang, Jingwen Jiang, Jiaxuan Jiang, Deming Wang, Zefeng Yang, Fengqi Zhou, Evan M Chen, Jill Liang, Yunhe Song, Fengbin Lin, Kyoko Ohno-Matsui, Jost B Jonas, Ying Han, Fei Li, Xiulan Zhang","doi":"10.1016/j.apjo.2024.100123","DOIUrl":"10.1016/j.apjo.2024.100123","url":null,"abstract":"Axial elongation continues in highly myopic adult eyes, even in the absence of pathologic changes such as posterior staphyloma or chorioretinal atrophy. This ongoing axial elongation leads to structural changes in the macular and peripapillary regions, including chorioretinal thinning, reduced vascular perfusion and optic disc tilting and rotation, among others. These alterations can affect the acquisition and interpretation of optical coherence tomography, optical coherence tomography angiography and fundus photographs, potentially introducing artifacts and diminishing the accuracy of glaucoma diagnosis in highly myopic eyes. In this review, we compared the progression patterns of axial elongation across populations with varying demographic characteristics, genetic and environmental backgrounds and ocular features. We also discussed the implications of axial elongation-induced ocular structural changes for diagnosing glaucoma in nonpathologic high myopia. Finally, we highlighted the prospects for enhancing the diagnostic efficacy of glaucoma in nonpathologic highly myopic populations.","PeriodicalId":8594,"journal":{"name":"Asia-Pacific Journal of Ophthalmology","volume":" ","pages":"100123"},"PeriodicalIF":3.7,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142823631","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Bilateral Coats' disease in a 5-year-old boy.

IF 3.7 3区医学

Asia-Pacific Journal of Ophthalmology Pub Date : 2024-11-01 Epub Date: 2024-12-05 DOI: 10.1016/j.apjo.2024.100119

Meng-Chen Chiang, Shawn H Tsai, Nan-Kai Wang, Yung-Jen Lai

引用次数: 0

Ophthalmology training trends: Insights from an anonymised survey of Australian ophthalmology trainees.

IF 3.7 3区医学

Asia-Pacific Journal of Ophthalmology Pub Date : 2024-11-01 Epub Date: 2024-12-05 DOI: 10.1016/j.apjo.2024.100120

William B Yates, Adrian T Fung, Clare Fraser, Robert Griffits, Anne Lee, Peter J McCluskey

引用次数: 0

Associations of optic nerve head morphology and peripapillary retinal nerve fibre layer thickness with myopic severity and treatment in children. 儿童视神经头形态和毛周视网膜神经纤维层厚度与近视严重程度和治疗的关系

IF 3.7 3区医学

Asia-Pacific Journal of Ophthalmology Pub Date : 2024-11-01 Epub Date: 2024-11-23 DOI: 10.1016/j.apjo.2024.100112

Bryan Sim, Rachel S Chong, Hla Myint Htoon, Maithily Balakrishnan, Noel A Brennan, Audrey Chia

{"title":"Associations of optic nerve head morphology and peripapillary retinal nerve fibre layer thickness with myopic severity and treatment in children.","authors":"Bryan Sim, Rachel S Chong, Hla Myint Htoon, Maithily Balakrishnan, Noel A Brennan, Audrey Chia","doi":"10.1016/j.apjo.2024.100112","DOIUrl":"10.1016/j.apjo.2024.100112","url":null,"abstract":"Purpose: This study aimed to investigate the longitudinal associations between myopic optic disc features and optical coherence tomography (OCT) measurements of peripapillary retinal nerve fibre layer (RNFL) thickness in young myopic children in Singapore.Methods: A prospective, single-site cohort study was conducted, involving children aged 7-16 years who participated in the PROM-Kids clinical cohort study from 2019 to 2022. Participants underwent annual assessments, including cycloplegic refraction, axial length measurements, fundus photography, and OCT imaging, with ocular magnification correction. Children were classified into low (LM, 0 to -3D), moderate (MM, -3.01 to -6D), and high (HM, > -6D) myopia, with or without treatment.Results: Data from 1000 children (right eye) were analyzed, including 521 with 2-year follow-up. At baseline, the mean age was 10.2 ± 1.6 years, with 46.4 % male and 90.7 % ethnic Chinese. HM children were older and exhibited greater optic disc tilt (ODT, 92 % vs. 80 %) and more peripapillary atrophy (PPA, 94 % vs. 73 %) compared to LM children. RNFL thickness decreased in the superior, inferior, and nasal quadrants but increased in the temporal quadrant with higher myopia. In the follow-up cohort, myopia progression was associated with thicker temporal quadrant and average RNFL, particularly in younger children. Prior treatment with myopia-control lenses was also associated with increased RNFL thickness in the superior quadrant.Conclusion: Optic disc changes occur early in life, even in low myopia. Increasing myopia is linked to varying RNFL thickness across quadrants and may be influenced by age and myopia treatment.","PeriodicalId":8594,"journal":{"name":"Asia-Pacific Journal of Ophthalmology","volume":" ","pages":"100112"},"PeriodicalIF":3.7,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142715104","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Challenges in myopia management and prevention: A call to action. 近视管理和预防面临的挑战：行动呼吁。

IF 3.7 3区医学

Asia-Pacific Journal of Ophthalmology Pub Date : 2024-11-01 Epub Date: 2024-11-22 DOI: 10.1016/j.apjo.2024.100111

Enne Hiu Ying Leung, Sun Li, Lizhen Chen, Dennis Shun Chiu Lam

引用次数: 0

Differences in anterior ocular biometric characteristics among 6-year-old children with different myopic shift rates: A 2-year longitudinal study.

IF 3.7 3区医学

Asia-Pacific Journal of Ophthalmology Pub Date : 2024-11-01 Epub Date: 2024-12-11 DOI: 10.1016/j.apjo.2024.100116

Yu Zhao, Yuhao Ye, Jingbin Geng, Jiayi Zhang, Zhe Zhang, Yiyong Xian, Yangyi Huang, Fang Liu, Ye Xu, Xingtao Zhou

{"title":"Differences in anterior ocular biometric characteristics among 6-year-old children with different myopic shift rates: A 2-year longitudinal study.","authors":"Yu Zhao, Yuhao Ye, Jingbin Geng, Jiayi Zhang, Zhe Zhang, Yiyong Xian, Yangyi Huang, Fang Liu, Ye Xu, Xingtao Zhou","doi":"10.1016/j.apjo.2024.100116","DOIUrl":"10.1016/j.apjo.2024.100116","url":null,"abstract":"Background: To investigate longitudinal changes in anterior ocular features during slow and fast myopic shift in 6-year-old children.Methods: In total, 242 eyes of first-year primary school children in Shanghai, China, were included in this study. All children underwent an initial examination and were subsequently followed-up for two years. All participants underwent comprehensive examinations, including ocular biometric assessment and cycloplegic autorefraction. Children were divided into two groups based on the degree of myopic shift in 2 years: group A (slow myopic shift, < 1.0 D, N = 145) and group B (fast myopic shift, > 1.0 D, N = 88). Detailed anterior ocular biometric data were compared between the two groups.Results: In both groups, the axial length and anterior chamber depth (ACD) increased significantly over the follow-up period (P < 0.001). Anterior corneal surface curvature showed a flattening trend in both flat and steep meridians in group A, while these parameters exhibited steepening changes in group B. Lens thickness (LT) decreased significantly from 3.60 ± 0.20 mm to 3.45 ± 0.17 mm in group B (P < 0.001), but not in group A (P = 0.387). The average lens tilt significantly decreased from 5.21 ± 1.26° to 4.95 ± 1.23° in group A (P = 0.043), but it exhibited no significant change in group B (P = 0.181). Furthermore, LT and ACD were significantly correlated with spherical equivalent changes (P < 0.01).Conclusions: Children with slow and fast myopic shift demonstrated comparable ACD deepening changes but showed distinct variations in corneal curvature and lens characteristics.","PeriodicalId":8594,"journal":{"name":"Asia-Pacific Journal of Ophthalmology","volume":" ","pages":"100116"},"PeriodicalIF":3.7,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142816823","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Is there an impending epidemic of myopia in Southeast Asia? An appraisal of the evidence.

IF 3.7 3区医学

Asia-Pacific Journal of Ophthalmology Pub Date : 2024-11-01 Epub Date: 2024-12-02 DOI: 10.1016/j.apjo.2024.100113

Ian George Morgan

{"title":"Is there an impending epidemic of myopia in Southeast Asia? An appraisal of the evidence.","authors":"Ian George Morgan","doi":"10.1016/j.apjo.2024.100113","DOIUrl":"10.1016/j.apjo.2024.100113","url":null,"abstract":"Predictions on the future prevalence of myopia suggest one of the Global Burden of Disease regions will develop an epidemic like in East Asia and Singapore in Southeast Asia. This paper analyses the available evidence on prevalence of myopia in this region, concluding that the bulk of the evidence suggests that the prevalence of myopia at the end of schooling is still modest, although two papers suggest that in young adults in Thailand and Indonesia, the prevalence of myopia may be approaching levels typical of the epidemic of myopia. It also analyses an indicator of expected years of education at school entry, as well as current educational levels of adults, using data from the calculation of the UN Human Development Index. It then analyses the results obtained by the countries of the Southeast Asian region in the PISA international surveys of student achievement. Neither of these educational indicators suggests an impending epidemic of myopia. There is a need for more data to clarify this uncertainty. It is suggested that future collection of data concentrate on determining the prevalence of myopia in young adults finishing their schooling. Even methodology as simple as determining levels of lowered visual acuity in senior school students should be sufficient to resolve the uncertainty. This group provides a sound basis for the prediction of future levels of myopia in the adult population, and avoids the impact of the high levels of myopia and high myopia associated with cataract development that occur in much of Southeast Asia.","PeriodicalId":8594,"journal":{"name":"Asia-Pacific Journal of Ophthalmology","volume":" ","pages":"100113"},"PeriodicalIF":3.7,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142779156","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Safety of repeated low-level red-light therapy for myopia: A systematic review. 重复低强度红光疗法治疗近视的安全性：系统回顾。

IF 3.7 3区医学

Asia-Pacific Journal of Ophthalmology Pub Date : 2024-11-01 Epub Date: 2024-12-12 DOI: 10.1016/j.apjo.2024.100124

Yanping Chen, Ruilin Xiong, Shaopeng Yang, Ziyu Zhu, Huangdong Li, Kaidi Xiang, Nathan Congdon, Wei Wang, Mingguang He

{"title":"Safety of repeated low-level red-light therapy for myopia: A systematic review.","authors":"Yanping Chen, Ruilin Xiong, Shaopeng Yang, Ziyu Zhu, Huangdong Li, Kaidi Xiang, Nathan Congdon, Wei Wang, Mingguang He","doi":"10.1016/j.apjo.2024.100124","DOIUrl":"10.1016/j.apjo.2024.100124","url":null,"abstract":"Purpose: Establishing the safety profile of repeated low-level red-light (RLRL) therapy is necessary prior to its widespread clinical implementation.Methods: We conducted a systematic review (International Prospective Register of Systematic Reviews, CRD42024516676) of articles across seven databases from inception through February 10, 2024, with keywords related to myopia and RLRL therapy. Pooled safety outcomes and risk-to-benefit ratios were reported, and incidence of side effects was compared with other antimyopia interventions.Results: Among 689 screened articles, 20 studies (2.90 %; median duration 9 months, longest 24 months) were analysed, encompassing 2380 participants aged 3-18 years and 1436 individuals undergoing RLRL therapy. Two case reports described an identical patient with reversible decline in visual acuity and optical coherence tomography (OCT) abnormalities, completely resolved 4 months after treatment cessation. No cases of permanent vision loss were reported. Temporary afterimage was the most common ocular symptom following treatment, resolving within 6 minutes in reported studies. The number needed to harm outweighed the number needed to treat by a ratio of 12.7-21.4 for a person with -3D to -8D myopia treated with RLRL therapy. Incidence of side effects from RLRL was 0.088 per 100 patient-years (95 % confidence interval, 0.02-0.50).Conclusions: No irreversible visual function loss or ocular structural damage was identified with RLRL. Fundus photography and OCT before and during therapy, alongside home monitoring of visual acuity and duration of afterimages, are necessary to identify side effects. Further adequately powered studies of longer duration are needed to evaluate long-term safety of RLRL.","PeriodicalId":8594,"journal":{"name":"Asia-Pacific Journal of Ophthalmology","volume":" ","pages":"100124"},"PeriodicalIF":3.7,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142821855","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0