Asia-Pacific Journal of Ophthalmology最新文献

IF 3.7 3区医学

Asia-Pacific Journal of Ophthalmology Pub Date : 2025-01-26 DOI: 10.1016/j.apjo.2025.100161

Moxin Chen, Qin Shu, Fang Li, Lin Li, Xianqun Fan

{"title":"The whole life cycle myopia management.","authors":"Moxin Chen, Qin Shu, Fang Li, Lin Li, Xianqun Fan","doi":"10.1016/j.apjo.2025.100161","DOIUrl":"10.1016/j.apjo.2025.100161","url":null,"abstract":"Myopia stands as a prevalent ocular condition with global implications, impacting individuals at various life stages. In school-age children and adolescents, uncorrected myopia impedes reading and academic performance. Among middle-aged and elderly populations, myopia poses severe risks such as macular degeneration, macular holes and retinal detachment, leading to irreversible visual impairment. The term \"myopia management\" is widely embraced by ophthalmic practitioners and optometry associations worldwide, encompassing strategies to correct refractive errors and ongoing assessment of disease progression, aiming to reduce the progression of myopia and axial elongation. To date, current management strategies for myopia include public health policies, optical solutions, medical interventions and surgical options, but these interventions are general and lack age specificity. Despite existing interventions, we propose the concept of \"Whole Life Cycle Myopia Management\" in this review. This approach outlined major risk factors of myopia through the whole life cycle, discussed current interventions for myopia and provided age-specific management strategies for myopia of eight different life stages-infancies, toddlers, preschoolers, school-age children, adolescents, young adults, middle-age and old-age, including the prevention of myopia onset, slowing of myopia progression and monitoring of myopia complications. Achieving the \"Whole Life Cycle Myopia Management\" requires collaborations efforts from government, schools, hospitals and families, to restore vision and enhance the quality of life for those individuals affected by myopia.","PeriodicalId":8594,"journal":{"name":"Asia-Pacific Journal of Ophthalmology","volume":" ","pages":"100161"},"PeriodicalIF":3.7,"publicationDate":"2025-01-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143057874","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Role of caffeine in slowing progression of myopia: 1-year results from a prospective, longitudinal clinical trial. 咖啡因在减缓近视进展中的作用：一项前瞻性纵向临床试验的1年结果。

IF 3.7 3区医学

Asia-Pacific Journal of Ophthalmology Pub Date : 2025-01-01 Epub Date: 2025-01-15 DOI: 10.1016/j.apjo.2025.100138

Huy D M Tran, Yen H Tran, Thao T X Ha, Tuan D Tran, Monica Jong, Minas Coroneo, Padmaja Sankaridurg

{"title":"Role of caffeine in slowing progression of myopia: 1-year results from a prospective, longitudinal clinical trial.","authors":"Huy D M Tran, Yen H Tran, Thao T X Ha, Tuan D Tran, Monica Jong, Minas Coroneo, Padmaja Sankaridurg","doi":"10.1016/j.apjo.2025.100138","DOIUrl":"10.1016/j.apjo.2025.100138","url":null,"abstract":"Purpose: To determine the role of topical caffeine in slowing progression of myopia, both as a standalone treatment and in combination with atropine.Methods: In a prospective, randomized, dispensing clinical trial, 96 children with myopia, aged 6-13 years, spherical equivalent (SE) from -0.50 diopters (D) to -6.00 D and astigmatism less than 2.00 D were randomly assigned to nightly use of either 2 % caffeine, 0.02 % atropine with 2 % caffeine (combination) or 0.02 % atropine eye drops. An additional 86 children with myopia were enrolled in a concurrent parallel group to wear single-vision (SV) spectacles. The primary outcomes were changes in SE and axial length (AL) over a period of 12 months for each group.Results: All groups progressed in myopia. At 12 months, the mean change in SE/AL was -0.76 ± 0.51 D / 0.37 ± 0.20 mm and -0.70 ± 0.55 D / 0.35 ± 0.23 mm with SV and 2 % caffeine, respectively. In comparison, progression was slower at -0.46 ± 0.50 D / 0.24 ± 0.19 mm and -0.47 ± 0.38 D / 0.23 ± 0.18 mm with atropine monotherapy and combination groups, respectively. Compared to the change in AL with SV, the change in AL was significantly less with 0.02 % atropine and the combination group (post hoc analysis, P = 0.024 and 0.007, respectively). Similarly, the change in SE was significantly less with 0.02 % atropine compared to the SV group (P = 0.027).Conclusions: Used as a standalone treatment, topical 2 % caffeine did not slow myopia progression. When combined with atropine, caffeine had no impact on the efficacy of atropine in slowing myopia.","PeriodicalId":8594,"journal":{"name":"Asia-Pacific Journal of Ophthalmology","volume":" ","pages":"100138"},"PeriodicalIF":3.7,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142997784","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

How to diagnose glaucoma in myopic eyes by detecting structural changes? 如何通过检测结构变化诊断近视眼青光眼？

IF 3.7 3区医学

Asia-Pacific Journal of Ophthalmology Pub Date : 2025-01-01 Epub Date: 2025-01-09 DOI: 10.1016/j.apjo.2025.100135

Yong Woo Kim, Ki Ho Park

{"title":"How to diagnose glaucoma in myopic eyes by detecting structural changes?","authors":"Yong Woo Kim, Ki Ho Park","doi":"10.1016/j.apjo.2025.100135","DOIUrl":"10.1016/j.apjo.2025.100135","url":null,"abstract":"Myopia is rapidly escalating globally, especially in East and Southeast Asia, where its prevalence among younger populations reaches alarming levels of 80-90 %. This surge contributes to a myopia epidemic linked to several ocular complications, including glaucoma. As myopic individuals age, the risk of developing glaucoma increases, and an additional concern arises from the growing frequency of refractive surgeries among younger individuals, making precise optic nerve assessments critical before surgery. Evaluating the optic nerve head (ONH) in myopic eyes is challenging, as structural changes due to myopia often resemble glaucomatous alterations. Techniques such as optical coherence tomography (OCT) have improved the examination of ONH microstructures, but interpreting results remains complex due to potential false-positive findings. Myopic eyes exhibit unique changes, such as peripapillary atrophy and altered neuroretinal rim configurations, making it crucial to distinguish these from true glaucomatous signs. Recent advancements in OCT technology and the establishment of myopia-specific normative databases have enhanced diagnostic accuracy. Parameters such as minimum rim width, ganglion cell-inner plexiform layer thickness and temporal raphe sign show promise in differentiating between glaucomatous and nonglaucomatous changes. Ultimately, a comprehensive approach incorporating multiple OCT metrics is essential for accurately diagnosing glaucoma in myopic patients. By integrating various structural evaluations and leveraging advanced imaging techniques, clinicians can better navigate the complexities of glaucoma diagnosis amidst the challenges posed by myopia. This review highlights the need for increased attention and tailored strategies in managing glaucoma risk within this increasingly affected population.","PeriodicalId":8594,"journal":{"name":"Asia-Pacific Journal of Ophthalmology","volume":" ","pages":"100135"},"PeriodicalIF":3.7,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142969517","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Treatment modalities and trends for hospitalized patients with neovascular glaucoma: A retrospective study of 10 years. 住院新生血管性青光眼患者的治疗方式和趋势：10年回顾性研究

IF 3.7 3区医学

Asia-Pacific Journal of Ophthalmology Pub Date : 2025-01-01 Epub Date: 2025-01-11 DOI: 10.1016/j.apjo.2025.100136

Huishan Lin, Xinbo Gao, Zhuoyi Wu, Wengian Tam, Wei Huang, Yue Dong, Xi Qin, Yao Liu, Chengguo Zuo, Mingkai Lin

{"title":"Treatment modalities and trends for hospitalized patients with neovascular glaucoma: A retrospective study of 10 years.","authors":"Huishan Lin, Xinbo Gao, Zhuoyi Wu, Wengian Tam, Wei Huang, Yue Dong, Xi Qin, Yao Liu, Chengguo Zuo, Mingkai Lin","doi":"10.1016/j.apjo.2025.100136","DOIUrl":"10.1016/j.apjo.2025.100136","url":null,"abstract":"To analyze the treatment modalities and trends for neovascular glaucoma (NVG) over the past 10 years, we conducted a retrospective analysis at Zhongshan Ophthalmic Center on 1331 NVG inpatients who received 1459 treatments for 1383 eyes between January 1, 2012, and December 31, 2021. Over time, we observed a progressive annual increase in both the number of patients and the volume of surgeries for NVG, with an annual percentage change (APC) of 10.23 % (95 % confidence interval [CI]: 5.5-15.2 %, P = 0.001) and 11.59 % (95 % CI: 6.6-16.9 %, P = 0.001), respectively. Drainage valve implantation (46.88 %), cyclodestructive procedures (22.55 %) and trabeculectomy (6.24 %) were the three most commonly selected treatment options. The frequency of drainage valve implantation (APC = 6.59 %, 95 % CI = 0.9-12.6 %, P = 0.028), cyclodestructive procedures (APC = 17.26 %, 95 % CI = 9.3-25.8 %, P = 0.001) and trabeculectomy (APC = 21.93 %, 95 % CI = 1.6-46.3 %, P = 0.036) increased. The proportion of drainage valve implantation gradually decreased (APC = -4.48 %, 95 % CI = -8.6 to -0.2 %, P = 0.042), while that of cyclodestructive procedures increased (APC = 5.08 %, 95 % CI = 0.6-9.8 %, P = 0.042), with no significant alteration observed in the proportion of trabeculectomy (APC = 9.26 %, 95 % CI = -8.8-30.9 %, P = 0.290). Over the course of the study, both the cases of NVG and the volume of related surgeries escalated year by year. Among the three most frequently employed procedures-drainage valve implantation, cyclodestructive procedures and trabeculectomy-annual frequency trends revealed an increase in drainage valve implantation alongside a decreasing proportion, while cyclodestructive procedures exhibited a rising trend in both frequency and proportion; simultaneously, trabeculectomy showed an increasing frequency without a significant change in its proportion.","PeriodicalId":8594,"journal":{"name":"Asia-Pacific Journal of Ophthalmology","volume":" ","pages":"100136"},"PeriodicalIF":3.7,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142977396","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Triterpenoid saponin-mediated recovery of visual deficits in age-related macular degeneration (AMD): Double-blind, placebo-controlled, randomised clinical trial. 三萜皂苷介导的老年性黄斑变性（AMD）视力缺陷恢复：双盲、安慰剂对照、随机临床试验

IF 3.7 3区医学

Asia-Pacific Journal of Ophthalmology Pub Date : 2025-01-01 Epub Date: 2025-01-14 DOI: 10.1016/j.apjo.2025.100143

Yunhee Lee, Eun-Jung Ahn, Soo-Wan Chae, Ali Aijaz Hussain

{"title":"Triterpenoid saponin-mediated recovery of visual deficits in age-related macular degeneration (AMD): Double-blind, placebo-controlled, randomised clinical trial.","authors":"Yunhee Lee, Eun-Jung Ahn, Soo-Wan Chae, Ali Aijaz Hussain","doi":"10.1016/j.apjo.2025.100143","DOIUrl":"10.1016/j.apjo.2025.100143","url":null,"abstract":"Purpose: Recovery rate of rod photoreceptor sensitivity (S2 gradient) following a bleach is reduced in age-related macular degeneration (AMD) due to diminished delivery of retinol across a grossly altered Bruch's membrane. Since triterpenoid saponins are known to improve transport across Bruch's, we have assessed their possible use for reversing the visual deficits in AMD.Design: Double-blind, placebo controlled randomised clinical trial.Methods: Altogether 11 AMD patients and seven age-matched control subjects were recruited to undertake a small proof-of-principle study. Dark adaptation curves were obtained and S2 gradients evaluated using a Humphrey Field Analyser. Following basal determination of S2 gradients, oral supplementation of saponins (200 mg/day) or placebo regime was instigated for a period of 4 months. S2 gradients were re-evaluated at two and four months.Results: Basal S2 gradients of the AMD cohort were determined as 0.41 ± 0.24 dB/min and those of the control subjects as 1.44 ± 0.1 dB/min. After two months of the saponin treatment, AMD subjects showed improved S2 gradients of 0.92 ± 0.23 dB/min (P < 0.005) with a further increase to 1.35 ± 0.19 dB/min at four months (P < 0.01), the latter not being significantly different from control subjects. S2 gradients in placebo subjects were unaltered.Conclusions: Oral supplementation with saponins results in reversing the reduced S2 gradients in AMD. This improvement in the transport properties of Bruch's is expected to slow, halt or reverse the progression of AMD.","PeriodicalId":8594,"journal":{"name":"Asia-Pacific Journal of Ophthalmology","volume":" ","pages":"100143"},"PeriodicalIF":3.7,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142998447","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Clinical practices on acute acquired comitant esotropia: A consensus statement proposed by the Council of Asia-Pacific Strabismus and Pediatric Ophthalmology Society. 急性获得性共同性内斜视的临床实践：亚太斜视理事会和儿童眼科学会提出的共识声明。

IF 3.7 3区医学

Asia-Pacific Journal of Ophthalmology Pub Date : 2025-01-01 Epub Date: 2025-01-11 DOI: 10.1016/j.apjo.2025.100134

Wen Wen, Sonal K Farzavandi, Miho Sato, Boon Long Quah, Simon T Ko, T S Surendran, An-Guor Wang, Jeong-Min Hwang, Rita S Sitorus, Shuan Dai, Wei Zhang, Kanxing Zhao, Jason C Yam, Frank Martin, Chen Zhao

引用次数: 0

Comment on the Article: Exaggerated immune response to fungal keratitis post-COVID19 vaccination. 文章评论：covid - 19疫苗接种后真菌性角膜炎的免疫反应夸大。

IF 3.7 3区医学

Asia-Pacific Journal of Ophthalmology Pub Date : 2025-01-01 Epub Date: 2025-01-15 DOI: 10.1016/j.apjo.2025.100147

Yann Bertolani, Albert Arnaiz-Camacho, Sara Martín Nalda

引用次数: 0

Genes for childhood myopia. 儿童近视的基因。

IF 3.7 3区医学

Asia-Pacific Journal of Ophthalmology Pub Date : 2025-01-01 Epub Date: 2025-01-13 DOI: 10.1016/j.apjo.2025.100139

Yu Yao Wang, Li Jia Chen, Clement C Tham, Jason C Yam, Chi Pui Pang

引用次数: 0

Medical registries: Factors impacting clinician engagement. 医疗登记：影响临床医生敬业度的因素。

IF 3.7 3区医学

Asia-Pacific Journal of Ophthalmology Pub Date : 2025-01-01 Epub Date: 2025-01-15 DOI: 10.1016/j.apjo.2025.100146

James Pietris, Shrirajh Satheakeerthy, Stephen Bacchi, Robert Casson, Dinesh Selva, Weng Onn Chan

引用次数: 0

Response to Letter to the Editor: Comment on "Exaggerated immune response to fungal keratitis post-COVID-19 vaccination". 对“covid -19疫苗接种后对真菌性角膜炎的过度免疫反应”的评论

IF 3.7 3区医学

Asia-Pacific Journal of Ophthalmology Pub Date : 2025-01-01 Epub Date: 2025-01-14 DOI: 10.1016/j.apjo.2025.100148

Isana Nakajima, Ken Fukuda, Tamaki Sumi, Kenji Yamashiro

引用次数: 0