Asia-Pacific Journal of Ophthalmology最新文献

{"title":"Corrigendum to \"Controversies, consensuses and guidelines on Small Incision Lenticule Extraction (SMILE) by the Academy of Asia-Pacific Professors of Ophthalmology (AAPPO) and the Asia-Pacific Myopia Society (APMS)\" [Asia-Pac J Ophthalmol (2025) 100221].","authors":"Kelvin H Wan, Xiao Ying Wang, Kenny H W Lai, Jorge L Alio, Marcus Ang, Colin Chan, Tommy C Y Chan, George P M Cheng, Ahmed Elsheikh, Jesper Hjortdal, Guofu Huang, Vishal Jhanji, Jodhbir S Mehta, Srinivas K Rao, Masaki Sato, Walter Sekundo, Namrata Sharma, Rohit Shetty, Yan Wang, Yueying Xiao, Yabo Yang, Changbin Zhai, Fengju Zhang, Xingtao Zhou, Dennis S C Lam","doi":"10.1016/j.apjo.2025.100226","DOIUrl":"https://doi.org/10.1016/j.apjo.2025.100226","url":null,"abstract":"","PeriodicalId":8594,"journal":{"name":"Asia-Pacific Journal of Ophthalmology","volume":" ","pages":"100226"},"PeriodicalIF":3.7,"publicationDate":"2025-07-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144641629","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Controversies, consensuses and guidelines on modern cataract surgery by the academy of Asia-Pacific professors of ophthalmology (AAPPO).","authors":"Sanjeev P Srinivas, Alvin L Young, Anders Behndig, David F Chang, Sorcha Ní Dhubhghaill, Youngsub Eom, Alex Hoi Fan, Oliver Findl, Kjell Gunnar Gundersen, Rohit C Khanna, Thomas Kohnen, Francis S Mah, Kevin M Miller, Mayank A Nanavaty, Rudy Nuijts, Tetsuro Oshika, Gede Pardianto, Nicolaas J Reus, Sanduk Ruit, Namrata Sharma, Rengaraj Venkatesh, Mingzhi Zhang, Ke Zheng, Srinivas K Rao, Jorge L Alió","doi":"10.1016/j.apjo.2025.100224","DOIUrl":"10.1016/j.apjo.2025.100224","url":null,"abstract":"<p><p>Phacoemulsification has revolutionized cataract surgery since its introduction by Charles Kelman in 1967, becoming the gold standard for cataract removal in most parts of the world. Despite its widespread adoption and high success rates, there exist controversies within the ophthalmic community regarding various aspects of the procedure. An international panel comprising 25 experts from 18 countries/territories was established by the Academy of Asia-Pacific Professors of Ophthalmology (AAPPO) to work on this consensus project. A total of 15 sections with 61 consensus statements were evaluated by the panel. Femtosecond laser assisted cataract surgery was not considered better than Phaco. An interferometer was considered essential for measuring the ocular parameters, and the need to choose an appropriate intraocular lens (IOL) formula was stressed. When considering multifocal IOLs, an assessment of the patient's personality profile, and a thorough discussion of the pros and cons of the choice before surgery was essential. Proper informed consent was also essential. The need to address complications like TASS promptly including a reassessment of operating rooms protocols was stressed. Finally, there was general agreement that manual surgeries have a significant role to play in eyes with large, dense nuclei and in populations where low-cost, high-volume surgery was necessary. Manual but sutureless approach was preferred where appropriate. Since there was agreement on about 60 % of the 61 consensus statements, it reflected that there were variations in the real-world practice. Further studies are warranted and a follow-up consensus exercise after more information is available is worth considering.</p>","PeriodicalId":8594,"journal":{"name":"Asia-Pacific Journal of Ophthalmology","volume":" ","pages":"100224"},"PeriodicalIF":3.7,"publicationDate":"2025-07-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144590363","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Association of shared gene polymorphisms for refraction and axial length with corneal biomechanical properties in children.","authors":"Ebenezer Zaabaar, Erica Shing, Ka Wai Kam, Yuzhou Zhang, Alvin L Young, Clement C Tham, Chi Pui Pang, Jason C Yam, Li Jia Chen","doi":"10.1016/j.apjo.2025.100225","DOIUrl":"10.1016/j.apjo.2025.100225","url":null,"abstract":"<p><strong>Purpose: </strong>To investigate the associations of single-nucleotide polymorphisms (SNPs) for axial length (AL) and spherical equivalent (SE) with corneal biomechanical parameters in children.</p><p><strong>Methods: </strong>A cohort of 2535 Chinese children, 4-12 years old, underwent measurements of corneal biomechanical properties, including corneal hysteresis (CH), corneal resistance factor (CRF), deformation amplitude (DA), peak distance (PD), highest concavity radius, as well as first and second applanation lengths and velocities (V1 and V2). Fifteen candidate SNPs for AL and SE were genotyped for association analyses.</p><p><strong>Results: </strong>Overall, ZC3H11B rs994767 and CHD7 rs437036 showed significant associations with DA (β = -0.016, P = 0.0012 and β = 0.018, P = 0.0012, respectively). CHD7 rs437036 was associated with DA (β = 0.030, P = 0.0021) in 4-7-year-old children and ZC3H11B rs994767 with CRF (β = 0.216, P = 0.0027) in 8-12-year-old children. AL genetic risk score (GRS) showed associations with DA (β = 1.625, P = 0.014) and V2 (β = -1.630, P = 0.0019), and SE GRS with CRF (β = -64.94, P = 0.038). Compared to the first, the second and fourth AL GRS quantiles were associated with CH (β = 0.258, P = 0.008; β = 0.303, P = 0.002, respectively) and CRF (β = 0.282, P = 0.014; β = 0.373, P = 0.001, respectively), while the fifth was associated with DA (β = 0.029, P = 0.006), PD (β = 0.158, P = 0.011), V2 (β = -0.037, P = 1.24 ×10^-5), and CH (β = 0.20, P = 0.041). The second SE GRS quantile was associated with V2 (β = -0.020, P = 0.02), and the fifth with CH (β = -0.235, P = 0.049), compared to the first.</p><p><strong>Conclusion: </strong>ZC3H11B and CHD7 SNPs for AL and SE, along with GRS for both traits, showed associations with various corneal biomechanical parameters, suggesting their potential influence on the structure, composition and shape of eye size-related ocular tissues in children.</p>","PeriodicalId":8594,"journal":{"name":"Asia-Pacific Journal of Ophthalmology","volume":" ","pages":"100225"},"PeriodicalIF":3.7,"publicationDate":"2025-07-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144574753","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Controversies, consensuses, and guidelines for acute primary angle closure attack (APACA) by the Asia-Pacific Glaucoma Society (APGS) and the Academy of Asia-Pacific Professors of Ophthalmology (AAPPO).","authors":"Poemen P Chan, Xiulan Zhang, Tin Aung, Paul T K Chew, Nathan Congdon, Tanuj Dada, Seng Kheong Fang, Mingguang He, Chan Yun Kim, Jimmy S M Lai, Jacky W Y Lee, Yuanbo Liang, Vijaya Lingam, Catherine Y Liu, Prin Rojanapongpun, Xinghuai Sun, Xin Tang, Clement C Y Tham","doi":"10.1016/j.apjo.2025.100223","DOIUrl":"https://doi.org/10.1016/j.apjo.2025.100223","url":null,"abstract":"<p><p>The Asia-Pacific Glaucoma Society (APGS), in collaboration with the Academy of Asia-Pacific Professors of Ophthalmology (AAPPO), convened a panel of 18 international experts from 10 countries/territories to identify areas of controversy and establish consensus on diagnosing and managing Acute Primary Angle Closure Attack (APACA). APACA is a relatively common and potentially vision-threatening ocular emergency, particularly in Chinese and Asian populations. With timely and appropriate intervention, favorable outcomes could be achieved. However, with the current treatment protocol, two areas need to be improved: 1) more rapid and consistent reduction of intraocular pressure (IOP), and 2) reducing the proportion of patients who develop chronic IOP elevation after resolution of an acute attack and successful laser peripheral iridotomy. The international panel of experts systematically revisited and debated alternative treatments to address the above issues. Consensus was evaluated using a five-point Likert scale (strongly agree, agree, neutral, disagree, and strongly disagree), in which each expert considered and voted anonymously and independently on each consensus statement. A statement consensus is established when the summation of votes for \"agree\" and \"strongly agree\" reaches a 75 % threshold. Argon laser peripheral iridoplasty, anterior chamber paracentesis, and laser pupilloplasty are considered appropriate and suitable options for rapid IOP reduction. Earlier phacoemulsification is effective in preventing further retinal ganglion cell loss and disease progression after APACA and is worth considering, provided adequate facilities and expertise are available. Further studies are warranted to evaluate the safety and efficacy of corneal indentation as a rapid and immediate treatment to lower IOP.</p>","PeriodicalId":8594,"journal":{"name":"Asia-Pacific Journal of Ophthalmology","volume":" ","pages":"100223"},"PeriodicalIF":3.7,"publicationDate":"2025-07-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144564318","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Controversies, consensuses and guidelines on Small Incision Lenticule Extraction (SMILE) by the Academy of Asia-Pacific Professors of Ophthalmology (AAPPO) and the Asia-Pacific Myopia Society (APMS).","authors":"Kelvin H Wan, Xiao Ying Wang, Kenny H W Lai, Jorge L Alio, Marcus Ang, Colin Chan, Tommy C Y Chan, George P M Cheng, Ahmed Elsheikh, Jesper Hjortdal, Guofu Huang, Vishal Jhanji, Jodhbir S Mehta, Srinivas K Rao, Masaki Sato, Walter Sekundo, Namrata Sharma, Rohit Shetty, Yan Wang, Yueying Xiao, Yabo Yang, Changbin Zhai, Fengju Zhang, Xingtao Zhou, Dennis S C Lam","doi":"10.1016/j.apjo.2025.100221","DOIUrl":"10.1016/j.apjo.2025.100221","url":null,"abstract":"<p><p>Small incision lenticule extraction (SMILE) surgery was developed in 2008 as an extension of the femtosecond lenticule extraction procedure. Over the years, SMILE has become a highly popular laser refractive surgery offering a minimally invasive alternative to LASIK for correcting myopia and myopic astigmatism. Despite its benefits such as a flapless femtosecond laser procedure with reduced corneal nerve disruption, the procedure's relative novelty necessitates standardization. Given the myriads of emerging information and variability, a panel of 22 international experts is formed by the Asia Pacific Myopic Society (APMS) and the Academy of Asia-Pacific Professors of Ophthalmology (AAPPO) to explore the controversy and to work out a consensus on SMILE. This consensus manuscript arises from a systematic exploration of current literature and is supported by the collective insights of international experts in the field of refractive surgery. The panel convened to review the issues, engage in discussion, develop proposals, and vote to establish consensus across four areas: 1) preoperative assessment, 2) preoperative surgical planning, 3) intraoperative considerations, and 4) postoperative management in a five-point Likert scale (strongly agree, agree, neutral, disagree and strongly disagree). Consensus was achieved when at least 75 % of the experts had voted for \"strongly agree\" or \"agree\" on the consensus statement concerned. 63 consensus statements were discussed, with 51 (81.0 %) statements reaching consensus. By establishing standardized consensus, this paper aims to reduce variability and enhance predictability and safety in refractive outcomes. Ongoing research is encouraged on issues where consensus could not be reached among the international panel of experts (IPE).</p>","PeriodicalId":8594,"journal":{"name":"Asia-Pacific Journal of Ophthalmology","volume":" ","pages":"100221"},"PeriodicalIF":3.7,"publicationDate":"2025-06-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144526301","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Controversy and Consensus on Posterior Chamber Phakic Intraocular Lens for the Correction of Myopia and Myopic Astigmatism in Healthy Phakic Eyes by the Academy of Asia-Pacific Professors of Ophthalmology (AAPPO) and the Asia-Pacific Myopia Society (APMS).","authors":"Kenny H W Lai, Xiao Ying Wang, Kelvin H Wan, Allon Barsam, Scott D Barnes, Alison Chiu, Arthur B Cummings, Alaa M Eldanasoury, Guofu Huang, Kazutaka Kamiya, Barbara Leyssens, Shiming Li, Mark Packer, Julian Stevens, Tae Keun Yoo, Lynn Yeo, Xingkai Zhan, Xingtao Zhou, Dennis S C Lam","doi":"10.1016/j.apjo.2025.100222","DOIUrl":"https://doi.org/10.1016/j.apjo.2025.100222","url":null,"abstract":"<p><p>Phakic Intraocular Lens (pIOL) has been studied for correction of high myopia and myopic astigmatism long before the advent of laser refractive surgery. It offers excellent visual and refractive outcomes, but the inherited risk of intraocular surgery cannot be overlooked. The posterior chamber pIOL (PC-pIOL), designed to be placed in the ciliary sulcus, may offer additional advantages compared to its anterior chamber counterparts. Given the complexity of sulcus anatomy and individual variations, controversies exist regarding perioperative management, implant selection, and operative techniques, necessitating standardisation. Given the emergence of novel approaches and long-term clinical data, a panel comprising 19 international experts from 9 countries/territories was formed by the Academy of Asia-Pacific Professors of Ophthalmology (AAPPO) and the Asia-Pacific Myopia Society (APMS). The panel critically reviewed the subject and synthesised 58 consensus statements that aim to provide evidence-based, real-world practice recommendations for optimal outcomes in PC-pIOL surgery.</p>","PeriodicalId":8594,"journal":{"name":"Asia-Pacific Journal of Ophthalmology","volume":" ","pages":"100222"},"PeriodicalIF":3.7,"publicationDate":"2025-06-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144526300","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Descemet membrane endothelial keratoplasty under failed sclerocorneal transplantation.","authors":"Thibaud Garcin, Mathilde Kaspi, Nacim Bouheraoua, Vincent Borderie","doi":"10.1016/j.apjo.2025.100220","DOIUrl":"10.1016/j.apjo.2025.100220","url":null,"abstract":"","PeriodicalId":8594,"journal":{"name":"Asia-Pacific Journal of Ophthalmology","volume":" ","pages":"100220"},"PeriodicalIF":3.7,"publicationDate":"2025-06-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144511483","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Longitudinal evaluation of Bruch's membrane opening-minimum rim width in Chinese children: The Hong Kong Children Eye Study.","authors":"Yi Li, Xiu Juan Zhang, Yuzhou Zhang, Ka Wai Kam, Alvin L Young, Patrick Ip, Wei Zhang, Li Jia Chen, Clement C Tham, Jost B Jonas, Kyoko Ohno-Matsui, Chi Pui Pang, Jason C Yam","doi":"10.1016/j.apjo.2025.100219","DOIUrl":"10.1016/j.apjo.2025.100219","url":null,"abstract":"<p><strong>Purpose: </strong>To evaluate longitudinal changes in Bruch's membrane opening-minimum rim width (BMO-MRW) and its associated factors in school children aged 6-8 years, over 3 years, based on the Hong Kong Children Eye Study.</p><p><strong>Methods: </strong>In this longitudinal study, 740 children received comprehensive ophthalmologic examinations at baseline and at 3-year follow-up visits. Based on their refractive status, they were divided into groups of persistent non-myopia, newly-developed myopia, and persistent myopia. Global and sectoral BMO-MRW, retinal nerve fiber layer (RNFL) thickness, BMO area, and disc area were all measured using spectral-domain optical coherence tomography (SD-OCT).</p><p><strong>Results: </strong>The mean age of the participants at baseline was 7.71 ± 1.01 years (range 6-8 years), and 352 (47.7 %) were males. The 3-year follow-up visit revealed a significant increase in all sectors of BMO-MRW, average global BMO-MRW changed from 339.3 ± 51.7 µm to 361.3 ± 57.8 µm. Children in the persistent myopia group and newly developed myopia group showed significantly faster rates of BMO-MRW growth in all sectors compared to children of the persistent non-myopia group (all P < 0.001). In multivariable linear regression analysis, global BMO-MRW enlargement increased with larger axial length elongation (β = 0.20, P < 0.001), larger BMO area enlargement (β = 0.21, P < 0.001), and RNFL thickness thickening (β = 0.45, P < 0.001). It decreased with larger baseline BMO-MRW (β = - 0.17, P < 0.001) and larger disc area enlargement (β = - 0.29, P < 0.001).</p><p><strong>Conclusions: </strong>Global and sectoral BMO-MRW increased over 3 years among school children aged 6-8 years, affected by larger axial elongation, larger BMO area enlargement, more marked RNFL thickening, and decrease in optic disc area.</p>","PeriodicalId":8594,"journal":{"name":"Asia-Pacific Journal of Ophthalmology","volume":" ","pages":"100219"},"PeriodicalIF":3.7,"publicationDate":"2025-06-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144339869","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Association of residential air pollution with visual impairment in adults: The UK Biobank study.","authors":"Ebenezer Zaabaar, Yuzhou Zhang, Ka Wai Kam, Yingan Li, Xiu Juan Zhang, Mary Ho, Dong Liu, Mandy Ph Ng, Patrick Ip, Alvin Young, Chi Pui Pang, Clement C Tham, Mei-Po Kwan, Li Jia Chen, Jason C Yam","doi":"10.1016/j.apjo.2025.100209","DOIUrl":"10.1016/j.apjo.2025.100209","url":null,"abstract":"<p><strong>Purpose: </strong>To investigate the association of joint exposure to residential air pollutants with different severities of visual impairment (VI) in adults.</p><p><strong>Methods: </strong>Exposure to particulate matter and oxides of nitrogen were evaluated in 95,246 adults aged 40-70 years. Joint exposure to the pollutants was calculated using principal component analysis to create an air pollution score. Subjects were categorized by distance visual acuity into bilateral normal vision, near normal vision, unilateral VI, socially significant VI, and blindness and low vision.</p><p><strong>Results: </strong>A unit rise in air pollution score was associated with 9.2 %, 4.1 %, and 1.8 % increased risks of blindness and low vision, adjusted OR (AOR) = 1.092 (95 % CI, 1.057-1.129); socially significant VI, AOR = 1.041 (95 % CI, 1.016-1.066); and unilateral VI, AOR = 1.018 (95 % CI, 1.007-1.029), respectively. Compared to subjects in the lowest quartile of air pollution score, those in the highest quartile had 69.2 %, 30.5 %, and 9.9 % greater risks of blindness and low vision, AOR = 1.692 (95 % CI, 1.355-2.114), socially significant VI, AOR = 1.305 (95 % CI, 1.127-1.513), and unilateral VI, AOR = 1.099 (95 % CI, 1.035-1.167), respectively while those in the third quartile had 40.5 % and 25.6 % higher risks of blindness and low vision, AOR = 1.405 (95 % CI, 1.121-1.760) and socially significant VI, AOR = 1.256 (95 % CI, 1.086-1.453), respectively. There was a significant trend of increasing risk of blindness and low vision, as well as socially significant VI, as pollution levels rose.</p><p><strong>Conclusion: </strong>Joint exposure to air pollutants increased the risks of poor vision and blindness, suggesting that reducing such exposure could alleviate the disease burden of VI.</p>","PeriodicalId":8594,"journal":{"name":"Asia-Pacific Journal of Ophthalmology","volume":" ","pages":"100209"},"PeriodicalIF":3.7,"publicationDate":"2025-05-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144131845","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Psychometric evaluation of the Japanese version of the Impact of Vision Impairment (IVI) questionnaire using Rasch analysis.","authors":"Saiko Matsumura, Eva K Fenwick, Momoko Kawakami, Seiji Takagi, Ecosse L Lamoureux, Yuichi Hori","doi":"10.1016/j.apjo.2025.100204","DOIUrl":"10.1016/j.apjo.2025.100204","url":null,"abstract":"","PeriodicalId":8594,"journal":{"name":"Asia-Pacific Journal of Ophthalmology","volume":" ","pages":"100204"},"PeriodicalIF":3.7,"publicationDate":"2025-05-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144109489","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}