Asia-Pacific Journal of Ophthalmology最新文献

{"title":"Association of residential air pollution with visual impairment in adults: The UK Biobank study.","authors":"Ebenezer Zaabaar, Yuzhou Zhang, Ka Wai Kam, Yingan Li, Xiu Juan Zhang, Mary Ho, Dong Liu, Mandy Ph Ng, Patrick Ip, Alvin Young, Chi Pui Pang, Clement C Tham, Mei-Po Kwan, Li Jia Chen, Jason C Yam","doi":"10.1016/j.apjo.2025.100209","DOIUrl":"10.1016/j.apjo.2025.100209","url":null,"abstract":"<p><strong>Purpose: </strong>To investigate the association of joint exposure to residential air pollutants with different severities of visual impairment (VI) in adults.</p><p><strong>Methods: </strong>Exposure to particulate matter and oxides of nitrogen were evaluated in 95,246 adults aged 40-70 years. Joint exposure to the pollutants was calculated using principal component analysis to create an air pollution score. Subjects were categorized by distance visual acuity into bilateral normal vision, near normal vision, unilateral VI, socially significant VI, and blindness and low vision.</p><p><strong>Results: </strong>A unit rise in air pollution score was associated with 9.2 %, 4.1 %, and 1.8 % increased risks of blindness and low vision, adjusted OR (AOR) = 1.092 (95 % CI, 1.057-1.129); socially significant VI, AOR = 1.041 (95 % CI, 1.016-1.066); and unilateral VI, AOR = 1.018 (95 % CI, 1.007-1.029), respectively. Compared to subjects in the lowest quartile of air pollution score, those in the highest quartile had 69.2 %, 30.5 %, and 9.9 % greater risks of blindness and low vision, AOR = 1.692 (95 % CI, 1.355-2.114), socially significant VI, AOR = 1.305 (95 % CI, 1.127-1.513), and unilateral VI, AOR = 1.099 (95 % CI, 1.035-1.167), respectively while those in the third quartile had 40.5 % and 25.6 % higher risks of blindness and low vision, AOR = 1.405 (95 % CI, 1.121-1.760) and socially significant VI, AOR = 1.256 (95 % CI, 1.086-1.453), respectively. There was a significant trend of increasing risk of blindness and low vision, as well as socially significant VI, as pollution levels rose.</p><p><strong>Conclusion: </strong>Joint exposure to air pollutants increased the risks of poor vision and blindness, suggesting that reducing such exposure could alleviate the disease burden of VI.</p>","PeriodicalId":8594,"journal":{"name":"Asia-Pacific Journal of Ophthalmology","volume":" ","pages":"100209"},"PeriodicalIF":3.7,"publicationDate":"2025-05-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144131845","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Geographic atrophy: understanding the relationship between structure and function.","authors":"Antoine Huang, Zhichao Wu, Georg Ansari, Leon Von Der Emde, Maximilian Pfau, Steffen Schmitz-Valckenberg, Monika Fleckenstein, Tiarnán D L Keenan, Srinivas R Sadda, Robyn H Guymer, Chui Ming Gemmy Cheung, Usha Chakravarthy","doi":"10.1016/j.apjo.2025.100207","DOIUrl":"https://doi.org/10.1016/j.apjo.2025.100207","url":null,"abstract":"<p><strong>Purpose: </strong>This review explores the complex relationship between anatomical alterations and functional consequences in geographic atrophy (GA), the advanced non-neovascular form of age-related macular degeneration. We examine the natural history, progression patterns, structural biomarkers, functional assessments, and structure-function correlations in GA.</p><p><strong>Methods: </strong>Experts contributed specialized knowledge on GA pathophysiology, imaging biomarkers, and functional assessment methods. We synthesized an understanding of the relationship between structural changes (including fundus autofluorescence patterns, optical coherence tomography markers, and novel biomarkers) and functional outcomes (visual acuity, microperimetry, reading performance, and patient-reported outcomes), drawing from authors' research expertise and relevant literature.</p><p><strong>Results: </strong>While GA is defined by visible areas of outer retinal atrophy, the structure-function relationship is complex and often discordant. Visual acuity incompletely reflects the functional impact of GA, as it may remain preserved until foveal involvement occurs. Microperimetric assessments reveal functional deficits extending beyond visible atrophic borders, with varying degrees of correlation between structural and functional metrics. Different fundus autofluorescence patterns demonstrate distinct functional implications and progression rates. Recent innovations in imaging and visual function testing offer enhanced characterization of disease progression.</p><p><strong>Conclusions: </strong>The complex relationship between structural and functional measures in GA reflects underlying pathophysiological mechanisms and has important implications for clinical trial endpoints and patient management. Multimodal assessment incorporating both structural and functional parameters is essential for the comprehensive evaluation and management of GA, particularly as novel therapeutic approaches emerge.</p>","PeriodicalId":8594,"journal":{"name":"Asia-Pacific Journal of Ophthalmology","volume":" ","pages":"100207"},"PeriodicalIF":3.7,"publicationDate":"2025-05-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144118691","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Updates on the clinical management of intraocular foreign body (IOFB).","authors":"Andrea Chor Kiu Au, Daniel Ho Tak Wong, Kenneth Kai Wang Li","doi":"10.1016/j.apjo.2025.100208","DOIUrl":"https://doi.org/10.1016/j.apjo.2025.100208","url":null,"abstract":"<p><p>This review aims to summarise recent literature in the past decade, focusing on new insights, management strategies, and technique modifications for intraocular foreign body (IOFB) cases. We discuss the latest epidemiological data, diagnostic assessments, and challenging presentations of IOFB. Imaging, particularly non-contrast helical computed tomography with thin cuts, is a valuable diagnostic adjunct. The administration of perioperative prophylactic systemic and intravitreal antibiotics may be useful in reducing endophthalmitis risk. We recommend the same stage IOFB removal with primary repair within 24hours whenever feasible. Furthermore, the latest updates on surgical planning, techniques, and instrumentation for IOFB removal, including crystalline lens management, IOFB extraction routes, and intraoperative adjuncts such as perfluorocarbon liquid, cohesive viscoelastic, and mitomycin-C are described. Various IOFB removal techniques including magnet-based, scaffold, suture-based, aspiration and bimanual methods, specialised and innovative instruments are also discussed. This review compiles the recent advancements and techniques, offering a comprehensive update on the clinical management and surgical removal of IOFB.</p>","PeriodicalId":8594,"journal":{"name":"Asia-Pacific Journal of Ophthalmology","volume":" ","pages":"100208"},"PeriodicalIF":3.7,"publicationDate":"2025-05-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144118705","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Psychometric evaluation of the Japanese version of the Impact of Vision Impairment (IVI) questionnaire using Rasch analysis.","authors":"Saiko Matsumura, Eva K Fenwick, Momoko Kawakami, Seiji Takagi, Ecosse L Lamoureux, Yuichi Hori","doi":"10.1016/j.apjo.2025.100204","DOIUrl":"10.1016/j.apjo.2025.100204","url":null,"abstract":"","PeriodicalId":8594,"journal":{"name":"Asia-Pacific Journal of Ophthalmology","volume":" ","pages":"100204"},"PeriodicalIF":3.7,"publicationDate":"2025-05-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144109489","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Digital twins in ophthalmology: Concepts, applications, and challenges.","authors":"Kezheng Xu, Xiaolan Chen, Bowen Liu, Kai Jin, Mingguang He, Danli Shi","doi":"10.1016/j.apjo.2025.100205","DOIUrl":"10.1016/j.apjo.2025.100205","url":null,"abstract":"","PeriodicalId":8594,"journal":{"name":"Asia-Pacific Journal of Ophthalmology","volume":" ","pages":"100205"},"PeriodicalIF":3.7,"publicationDate":"2025-05-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144085701","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Retinal toxicity after intracameral cefuroxime following cataract surgery.","authors":"Xuejuan Cheng, Lu Qiu, Fei Cong, Lei Gao","doi":"10.1016/j.apjo.2025.100206","DOIUrl":"10.1016/j.apjo.2025.100206","url":null,"abstract":"","PeriodicalId":8594,"journal":{"name":"Asia-Pacific Journal of Ophthalmology","volume":" ","pages":"100206"},"PeriodicalIF":3.7,"publicationDate":"2025-05-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143963591","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Vision impairment-related burden of disease.","authors":"Jost B Jonas","doi":"10.1016/j.apjo.2025.100203","DOIUrl":"10.1016/j.apjo.2025.100203","url":null,"abstract":"","PeriodicalId":8594,"journal":{"name":"Asia-Pacific Journal of Ophthalmology","volume":" ","pages":"100203"},"PeriodicalIF":3.7,"publicationDate":"2025-05-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143970268","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Vacuum evaporation in the vitreous cavity.","authors":"Alexander Jessup, Andrew Chang","doi":"10.1016/j.apjo.2025.100201","DOIUrl":"10.1016/j.apjo.2025.100201","url":null,"abstract":"","PeriodicalId":8594,"journal":{"name":"Asia-Pacific Journal of Ophthalmology","volume":" ","pages":"100201"},"PeriodicalIF":3.7,"publicationDate":"2025-04-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143967289","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Global burden of blindness and vision loss among children and adolescents: A systematic analysis for the global burden of disease study 2021.","authors":"Yinwen Li, Yiyang Shu, Tianwei Qian, Yuzhou Zhang, Lijia Chen, Jason C Yam","doi":"10.1016/j.apjo.2025.100200","DOIUrl":"https://doi.org/10.1016/j.apjo.2025.100200","url":null,"abstract":"<p><strong>Aim: </strong>This study investigates the global burden of vision impairment caused by refraction disorders, near vision loss, and other vision loss among children and adolescents from 1990 to 2021. The analysis is categorized globally by sex, age, and socio-demographic index (SDI), with a focus on predicting trends to 2035.</p><p><strong>Methods: </strong>Data weas obtained from the Global Burden of Disease Study 2021. We reported the prevalence and disability-adjusted life-years (DALYs) of vision impairment due to refraction disorders, near vision loss, and other vision loss globally. Then, we described the prevalence and DALYs numbers and rates by sex, SDI and age. Next, we analyzed the relationship between rate and SDI. Finally, bayesian age-period-cohort (BAPC) analysis model was used to predict the trends from 2022 to 2035 globally by sex and age.</p><p><strong>Results: </strong>The prevalence and DALYs rates for refraction disorders had a statistically significant trend of reduction in four age groups globally and were positively associated with SDI. The prevalence and DALYs rates for near vision loss were increasing in four age groups, and were negatively associated with SDI. The BAPC model indicates that the age-specific prevalence and DALYs rates of refraction disorders and other vision loss in both men and women will remain on a downward trend until 2035, while near vision loss continues to rise.</p><p><strong>Conclusions: </strong>The findings underscore that there are extensive variations based on the type of vision impairment, age group, sex and SDI. Policies should be tailored to specific types in order to effectively alleviate the burden.</p>","PeriodicalId":8594,"journal":{"name":"Asia-Pacific Journal of Ophthalmology","volume":" ","pages":"100200"},"PeriodicalIF":3.7,"publicationDate":"2025-04-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143976273","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A rare case of caruncular actinomycosis presenting with tumor-like features.","authors":"Tatsuya Sakamoto, Kentaro Sueoka, Taiichiro Chikama","doi":"10.1016/j.apjo.2025.100202","DOIUrl":"https://doi.org/10.1016/j.apjo.2025.100202","url":null,"abstract":"","PeriodicalId":8594,"journal":{"name":"Asia-Pacific Journal of Ophthalmology","volume":" ","pages":"100202"},"PeriodicalIF":3.7,"publicationDate":"2025-04-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143967287","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}