Asia-Pacific Journal of Ophthalmology最新文献

Diabetic Blindness Remains a Big Challenge Despite All Recent Advancements in Diagnostics and Treatments 尽管诊断和治疗技术不断进步，糖尿病性失明仍然是一个巨大的挑战。

IF 3.7 3区医学

Asia-Pacific Journal of Ophthalmology Pub Date : 2024-09-01 DOI: 10.1016/j.apjo.2024.100105

引用次数: 0

UBM helps differentiate sulcus or in-the-bag IOL placement UBM 帮助区分人工晶体植入是囊内植入还是囊外植入。

IF 3.7 3区医学

Asia-Pacific Journal of Ophthalmology Pub Date : 2024-09-01 DOI: 10.1016/j.apjo.2024.100088

引用次数: 0

Long-term Outcomes of Combined Phacotrabeculectomy Surgery in a Singapore Tertiary Hospital 新加坡一家三级医院的咽喉切除联合手术的长期疗效。

IF 3.7 3区医学

Asia-Pacific Journal of Ophthalmology Pub Date : 2024-09-01 DOI: 10.1016/j.apjo.2024.100102

{"title":"Long-term Outcomes of Combined Phacotrabeculectomy Surgery in a Singapore Tertiary Hospital","authors":"","doi":"10.1016/j.apjo.2024.100102","DOIUrl":"10.1016/j.apjo.2024.100102","url":null,"abstract":"<div><h3>Purpose</h3><div>To describe the long-term outcomes of phacotrabeculectomy from a tertiary glaucoma service in Singapore.</div></div><div><h3>Design</h3><div>Retrospective case series.</div></div><div><h3>Methods</h3><div>Seven hundred ninety-six eyes of 698 patients who underwent phacotrabeculectomy surgery at the Singapore National Eye Centre between 2005 and 2007 with a minimum follow-up of three years were included. The primary outcome measure was intraocular pressure (IOP). Secondary outcomes included best-corrected visual acuity (BCVA), number of glaucoma medications, and surgical complications.</div></div><div><h3>Results</h3><div>The mean age was 69.5 years, 51 % were male, and 86 % were Chinese. Most eyes had primary glaucoma (90.6 %). The mean follow-up duration was 9.4 years. The overall success rate at three years was 97 % if surgical success was defined as IOP ≤ 21 mm Hg, 92 % if IOP ≤ 18 mm Hg, 66 % if IOP ≤ 15 mm Hg. By Kaplan–Meier survival analysis over 13 years, the cumulative success rate fell from 98.1 % to 89.1 % if IOP ≤ 21 mm Hg, 98.1–76.9 % if IOP ≤ 18 mm Hg, 98–50.3 % if IOP ≤ 15 mm Hg. The postoperative IOP improved significantly at all time points (<em>P</em> < 0.05) and 72 % had at least 20 % IOP reduction. There was a slight improvement in postoperative BCVA (<em>P</em> < 0.05). The mean number of glaucoma medications was reduced postoperatively (<em>P</em> < 0.001). There were no significant risk factors for surgical failure.</div></div><div><h3>Conclusions</h3><div>Phacotrabeculectomy was found to be safe, resulting in clinically significant IOP lowering for 13 years with reduced dependency on glaucoma medications and improved BCVA.</div></div>","PeriodicalId":8594,"journal":{"name":"Asia-Pacific Journal of Ophthalmology","volume":null,"pages":null},"PeriodicalIF":3.7,"publicationDate":"2024-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142340186","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Bilateral Retinal Detachment Associated with Ascaris suum Infection 与蛔虫感染有关的双侧视网膜脱离

IF 3.7 3区医学

Asia-Pacific Journal of Ophthalmology Pub Date : 2024-09-01 DOI: 10.1016/j.apjo.2024.100100

引用次数: 0

Advances in understanding and management of IgG4-related ophthalmic disease 对 IgG4 相关眼科疾病的认识和管理进展。

IF 3.7 3区医学

Asia-Pacific Journal of Ophthalmology Pub Date : 2024-09-01 DOI: 10.1016/j.apjo.2024.100101

引用次数: 0

Acute Macular Neuroretinopathy Associated with COVID-19 Pandemic: A Real-world Observation Study 与 COVID-19 大流行相关的急性黄斑神经视网膜病变：真实世界观察研究

IF 3.7 3区医学

Asia-Pacific Journal of Ophthalmology Pub Date : 2024-09-01 DOI: 10.1016/j.apjo.2024.100103

{"title":"Acute Macular Neuroretinopathy Associated with COVID-19 Pandemic: A Real-world Observation Study","authors":"","doi":"10.1016/j.apjo.2024.100103","DOIUrl":"10.1016/j.apjo.2024.100103","url":null,"abstract":"<div><h3>Purpose</h3><div>To evaluate the clinical and retinal imaging features of Chinese patients with acute macular neuroretinopathy (AMN) associated with COVID-19.</div></div><div><h3>Design</h3><div>A prospective observational study.</div></div><div><h3>Methods</h3><div>Retinal imaging, including color fundus photography, near-infrared imaging (NIR), swept-source optical coherence tomography (SS-OCT), optical coherence tomography angiography (OCTA), and Humphrey perimetry, were conducted for each case.</div></div><div><h3>Results</h3><div>All cases were included within the first three months following the pandemic outbreak. A total of 12 male patients (36.36 %) and 21 female patients (63.64 %) were prospectively recruited, and 29 cases (87.88 %) were bilaterally affected. The median interval between the onset of fever and the appearance of ocular symptoms was two days (range, 0.5–5.0 days). Apart from the outer retinal changes typical of AMN, changes in the inner retinal layers were observed, including intraretinal hemorrhage (8.06 %), cotton wool spots (9.68 %), and paracentral acute middle maculopathy (PAMM) (8.06 %). Smaller retinal inner nuclear layer hyperreflective speckles (RIHS) (41.94 %) were identified as a distinguishing feature from typical PAMM. Voids of vessel signals were found in the superficial (11.54 %), intermediate (82.69 %), and deep capillary plexus (98.08 %), and in the choriocapillaris (19.23 %) on OCTA. Humphrey perimetry illustrated central, paracentral, and peripheral scotomas. The occult lesions associated with AMN, PAMM, and some of the RIHS illustrated by OCT were visualized topographically and further confirmed by OCTA as perfusion defects.</div></div><div><h3>Conclusion</h3><div>An increase in AMN cases correlated with the SARS-CoV-2 outbreak. Additional features, including widespread inner retinal perfusion deficits, were observed and may serve as potential biomarkers for systemic microcirculation dysregulation in COVID-19.</div></div>","PeriodicalId":8594,"journal":{"name":"Asia-Pacific Journal of Ophthalmology","volume":null,"pages":null},"PeriodicalIF":3.7,"publicationDate":"2024-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142340184","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Patient Perceptions Regarding the Use of Eyeglasses Among Ophthalmologists 患者对眼科医生使用眼镜的看法。

IF 3.7 3区医学

Asia-Pacific Journal of Ophthalmology Pub Date : 2024-09-01 DOI: 10.1016/j.apjo.2024.100099

引用次数: 0

Real-World Large Sample Assessment of Drug-related Dry Eye Risk: Based on the FDA Adverse Event Reporting System Database 药物相关干眼症风险的真实世界大样本评估：基于 FDA 不良事件报告系统数据库。

IF 3.7 3区医学

Asia-Pacific Journal of Ophthalmology Pub Date : 2024-09-01 DOI: 10.1016/j.apjo.2024.100104

{"title":"Real-World Large Sample Assessment of Drug-related Dry Eye Risk: Based on the FDA Adverse Event Reporting System Database","authors":"","doi":"10.1016/j.apjo.2024.100104","DOIUrl":"10.1016/j.apjo.2024.100104","url":null,"abstract":"<div><h3>Purpose and design</h3><div>This study aimed to evaluate the risk of drug-related dry eye using real-world data, underscoring the significance of tracing pharmacological etiology for distinct clinical types of dry eye.</div></div><div><h3>Methods</h3><div>Analyzing adverse event reports in the Food and Drug Administration Adverse Event Reporting System (FAERS) from January 2004 to September 2023, we employed disproportionality analysis and the Bayesian confidence propagation neural network algorithm. The analysis involved categorizing drugs causing dry eye, assessing risk levels, and conducting segmental assessments based on the time of onset of drug-related dry eye adverse reactions.</div></div><div><h3>Results</h3><div>In the FAERS database, adverse reactions related to dry eye were linked to 1160 drugs. Disproportionality analysis identified 33 drugs with significant risk, notably in ophthalmic (brimonidine, bimatoprost), oncology (tisotumab vedotin, erdafitinib), and other medications (isotretinoin, oxymetazoline). The top three drugs with the highest risk of drug-related dry eye are isotretinoin (Bayesian confidence propagation neural network (BCPNN) = 6.88), tisotumab vedotin (BCPNN = 6.88), and brimonidine (BCPNN = 6.77). Among different categories of drugs, respiratory medications have the shortest mean onset time for drug-related dry eye, averaging 50.99 days. The prevalence skewed towards females (69.9 %), particularly in menopausal and elderly individuals (45–70 years old, mean age 54.7 ± 18.2). Reports of drug-related dry eye adverse reactions showed an annual increase.</div></div><div><h3>Conclusion</h3><div>Informed clinical decision-making is crucial for preventing drug-related dry eye. Assessing the risk of dry eyes associated with both local and systemic medications helps optimize treatment and provide necessary cautionary information.</div></div>","PeriodicalId":8594,"journal":{"name":"Asia-Pacific Journal of Ophthalmology","volume":null,"pages":null},"PeriodicalIF":3.7,"publicationDate":"2024-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142340187","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Accuracy of large language models in answering ophthalmology board-style questions: A meta-analysis 大语言模型在回答眼科委员会类型问题时的准确性：元分析。

IF 3.7 3区医学

Asia-Pacific Journal of Ophthalmology Pub Date : 2024-09-01 DOI: 10.1016/j.apjo.2024.100106

{"title":"Accuracy of large language models in answering ophthalmology board-style questions: A meta-analysis","authors":"","doi":"10.1016/j.apjo.2024.100106","DOIUrl":"10.1016/j.apjo.2024.100106","url":null,"abstract":"<div><h3>Purpose</h3><div>To evaluate the accuracy of large language models (LLMs) in answering ophthalmology board-style questions.</div></div><div><h3>Design</h3><div>Meta-analysis.</div></div><div><h3>Methods</h3><div>Literature search was conducted using PubMed and Embase in March 2024. We included full-length articles and research letters published in English that reported the accuracy of LLMs in answering ophthalmology board-style questions. Data on LLM performance, including the number of questions submitted and correct responses generated, were extracted for each question set from individual studies. Pooled accuracy was calculated using a random-effects model. Subgroup analyses were performed based on the LLMs used and specific ophthalmology topics assessed.</div></div><div><h3>Results</h3><div>Among the 14 studies retrieved, 13 (93 %) tested LLMs on multiple ophthalmology topics. ChatGPT-3.5, ChatGPT-4, Bard, and Bing Chat were assessed in 12 (86 %), 11 (79 %), 4 (29 %), and 4 (29 %) studies, respectively. The overall pooled accuracy of LLMs was 0.65 (95 % CI: 0.61–0.69). Among the different LLMs, ChatGPT-4 achieved the highest pooled accuracy at 0.74 (95 % CI: 0.73–0.79), while ChatGPT-3.5 recorded the lowest at 0.52 (95 % CI: 0.51–0.54). LLMs performed best in “pathology” (0.78 [95 % CI: 0.70–0.86]) and worst in “fundamentals and principles of ophthalmology” (0.52 [95 % CI: 0.48–0.56]).</div></div><div><h3>Conclusions</h3><div>The overall accuracy of LLMs in answering ophthalmology board-style questions was acceptable but not exceptional, with ChatGPT-4 and Bing Chat being top-performing models. Performance varied significantly based on specific ophthalmology topics tested. Inconsistent performances are of concern, highlighting the need for future studies to include ophthalmology board-style questions with images to more comprehensively examine the competency of LLMs.</div></div>","PeriodicalId":8594,"journal":{"name":"Asia-Pacific Journal of Ophthalmology","volume":null,"pages":null},"PeriodicalIF":3.7,"publicationDate":"2024-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142387538","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Current research and future strategies for the management of vision-threatening diabetic retinopathy 治疗危及视力的糖尿病视网膜病变的当前研究和未来策略。

IF 3.7 3区医学

Asia-Pacific Journal of Ophthalmology Pub Date : 2024-09-01 DOI: 10.1016/j.apjo.2024.100109

引用次数: 0