Kelvin H Wan, Xiao Ying Wang, Kenny H W Lai, Jorge L Alio, Marcus Ang, Colin Chan, Tommy C Y Chan, George P M Cheng, Ahmed Elsheikh, Jesper Hjortdal, Guofu Huang, Vishal Jhanji, Jodhbir S Mehta, Srinivas K Rao, Masaki Sato, Walter Sekundo, Namrata Sharma, Rohit Shetty, Yan Wang, Yueying Xiao, Yabo Yang, Changbin Zhai, Fengju Zhang, Xingtao Zhou, Dennis S C Lam
{"title":"Controversy and Consensus on Small Incision Lenticule Extraction (SMILE) by the Academy of Asia-Pacific Professors of Ophthalmology (AAPPO) and the Asia-Pacific Myopia Society (APMS).","authors":"Kelvin H Wan, Xiao Ying Wang, Kenny H W Lai, Jorge L Alio, Marcus Ang, Colin Chan, Tommy C Y Chan, George P M Cheng, Ahmed Elsheikh, Jesper Hjortdal, Guofu Huang, Vishal Jhanji, Jodhbir S Mehta, Srinivas K Rao, Masaki Sato, Walter Sekundo, Namrata Sharma, Rohit Shetty, Yan Wang, Yueying Xiao, Yabo Yang, Changbin Zhai, Fengju Zhang, Xingtao Zhou, Dennis S C Lam","doi":"10.1016/j.apjo.2025.100221","DOIUrl":"https://doi.org/10.1016/j.apjo.2025.100221","url":null,"abstract":"<p><p>Small incision lenticule extraction (SMILE) surgery was developed in 2008 as an extension of the femtosecond lenticule extraction procedure. Over the years, SMILE has become a highly popular laser refractive surgery offering a minimally invasive alternative to LASIK for correcting myopia and myopic astigmatism. Despite its benefits such as a flapless femtosecond laser procedure with reduced corneal nerve disruption, the procedure's relative novelty necessitates standardization. Given the myriads of emerging information and variability, a panel of 22 international experts is formed by the Asia Pacific Myopic Society (APMS) and the Academy of Asia-Pacific Professors of Ophthalmology (AAPPO) to explore the controversy and to work out a consensus on SMILE. This consensus manuscript arises from a systematic exploration of current literature and is supported by the collective insights of international experts in the field of refractive surgery. The panel convened to review the issues, engage in discussion, develop proposals, and vote to establish consensus across four areas: 1) preoperative assessment, 2) preoperative surgical planning, 3) intraoperative considerations, and 4) postoperative management in a five-point Likert scale (strongly agree, agree, neutral, disagree and strongly disagree). Consensus was achieved when at least 75% of the experts had voted for \"strongly agree\" or \"agree\" on the consensus statement concerned. 63 consensus statements were discussed, with 51 (81.0%) statements reaching consensus. By establishing standardized consensus, this paper aims to reduce variability and enhance predictability and safety in refractive outcomes. Ongoing research is encouraged on issues where consensus could not be reached among the international panel of experts (IPE).</p>","PeriodicalId":8594,"journal":{"name":"Asia-Pacific Journal of Ophthalmology","volume":" ","pages":"100221"},"PeriodicalIF":3.7,"publicationDate":"2025-06-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144526301","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Kenny H W Lai, Xiao Ying Wang, Kelvin H Wan, Allon Barsam, Scott D Barnes, Alison Chiu, Arthur B Cummings, Alaa M Eldanasoury, Guofu Huang, Kazutaka Kamiya, Barbara Leyssens, Shiming Li, Mark Packer, Julian Stevens, Tae Keun Yoo, Lynn Yeo, Xingkai Zhan, Xingtao Zhou, Dennis S C Lam
{"title":"Controversy and Consensus on Posterior Chamber Phakic Intraocular Lens for the Correction of Myopia and Myopic Astigmatism in Healthy Phakic Eyes by the Academy of Asia-Pacific Professors of Ophthalmology (AAPPO) and the Asia-Pacific Myopia Society (APMS).","authors":"Kenny H W Lai, Xiao Ying Wang, Kelvin H Wan, Allon Barsam, Scott D Barnes, Alison Chiu, Arthur B Cummings, Alaa M Eldanasoury, Guofu Huang, Kazutaka Kamiya, Barbara Leyssens, Shiming Li, Mark Packer, Julian Stevens, Tae Keun Yoo, Lynn Yeo, Xingkai Zhan, Xingtao Zhou, Dennis S C Lam","doi":"10.1016/j.apjo.2025.100222","DOIUrl":"https://doi.org/10.1016/j.apjo.2025.100222","url":null,"abstract":"<p><p>Phakic Intraocular Lens (pIOL) has been studied for correction of high myopia and myopic astigmatism long before the advent of laser refractive surgery. It offers excellent visual and refractive outcomes, but the inherited risk of intraocular surgery cannot be overlooked. The posterior chamber pIOL (PC-pIOL), designed to be placed in the ciliary sulcus, may offer additional advantages compared to its anterior chamber counterparts. Given the complexity of sulcus anatomy and individual variations, controversies exist regarding perioperative management, implant selection, and operative techniques, necessitating standardisation. Given the emergence of novel approaches and long-term clinical data, a panel comprising 19 international experts from 9 countries/territories was formed by the Academy of Asia-Pacific Professors of Ophthalmology (AAPPO) and the Asia-Pacific Myopia Society (APMS). The panel critically reviewed the subject and synthesised 58 consensus statements that aim to provide evidence-based, real-world practice recommendations for optimal outcomes in PC-pIOL surgery.</p>","PeriodicalId":8594,"journal":{"name":"Asia-Pacific Journal of Ophthalmology","volume":" ","pages":"100222"},"PeriodicalIF":3.7,"publicationDate":"2025-06-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144526300","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Yi Li, Xiu Juan Zhang, Yuzhou Zhang, Ka Wai Kam, Alvin L Young, Patrick Ip, Wei Zhang, Li Jia Chen, Clement C Tham, Jost B Jonas, Kyoko Ohno-Matsui, Chi Pui Pang, Jason C Yam
{"title":"Longitudinal evaluation of Bruch's membrane opening-minimum rim width in Chinese children: The Hong Kong Children Eye Study.","authors":"Yi Li, Xiu Juan Zhang, Yuzhou Zhang, Ka Wai Kam, Alvin L Young, Patrick Ip, Wei Zhang, Li Jia Chen, Clement C Tham, Jost B Jonas, Kyoko Ohno-Matsui, Chi Pui Pang, Jason C Yam","doi":"10.1016/j.apjo.2025.100219","DOIUrl":"10.1016/j.apjo.2025.100219","url":null,"abstract":"<p><strong>Purpose: </strong>To evaluate longitudinal changes in Bruch's membrane opening-minimum rim width (BMO-MRW) and its associated factors in school children aged 6-8 years, over 3 years, based on the Hong Kong Children Eye Study.</p><p><strong>Methods: </strong>In this longitudinal study, 740 children received comprehensive ophthalmologic examinations at baseline and at 3-year follow-up visits. Based on their refractive status, they were divided into groups of persistent non-myopia, newly-developed myopia, and persistent myopia. Global and sectoral BMO-MRW, retinal nerve fiber layer (RNFL) thickness, BMO area, and disc area were all measured using spectral-domain optical coherence tomography (SD-OCT).</p><p><strong>Results: </strong>The mean age of the participants at baseline was 7.71 ± 1.01 years (range 6-8 years), and 352 (47.7 %) were males. The 3-year follow-up visit revealed a significant increase in all sectors of BMO-MRW, average global BMO-MRW changed from 339.3 ± 51.7 µm to 361.3 ± 57.8 µm. Children in the persistent myopia group and newly developed myopia group showed significantly faster rates of BMO-MRW growth in all sectors compared to children of the persistent non-myopia group (all P < 0.001). In multivariable linear regression analysis, global BMO-MRW enlargement increased with larger axial length elongation (β = 0.20, P < 0.001), larger BMO area enlargement (β = 0.21, P < 0.001), and RNFL thickness thickening (β = 0.45, P < 0.001). It decreased with larger baseline BMO-MRW (β = - 0.17, P < 0.001) and larger disc area enlargement (β = - 0.29, P < 0.001).</p><p><strong>Conclusions: </strong>Global and sectoral BMO-MRW increased over 3 years among school children aged 6-8 years, affected by larger axial elongation, larger BMO area enlargement, more marked RNFL thickening, and decrease in optic disc area.</p>","PeriodicalId":8594,"journal":{"name":"Asia-Pacific Journal of Ophthalmology","volume":" ","pages":"100219"},"PeriodicalIF":3.7,"publicationDate":"2025-06-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144339869","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Ebenezer Zaabaar, Yuzhou Zhang, Ka Wai Kam, Yingan Li, Xiu Juan Zhang, Mary Ho, Dong Liu, Mandy Ph Ng, Patrick Ip, Alvin Young, Chi Pui Pang, Clement C Tham, Mei-Po Kwan, Li Jia Chen, Jason C Yam
{"title":"Association of residential air pollution with visual impairment in adults: The UK Biobank study.","authors":"Ebenezer Zaabaar, Yuzhou Zhang, Ka Wai Kam, Yingan Li, Xiu Juan Zhang, Mary Ho, Dong Liu, Mandy Ph Ng, Patrick Ip, Alvin Young, Chi Pui Pang, Clement C Tham, Mei-Po Kwan, Li Jia Chen, Jason C Yam","doi":"10.1016/j.apjo.2025.100209","DOIUrl":"10.1016/j.apjo.2025.100209","url":null,"abstract":"<p><strong>Purpose: </strong>To investigate the association of joint exposure to residential air pollutants with different severities of visual impairment (VI) in adults.</p><p><strong>Methods: </strong>Exposure to particulate matter and oxides of nitrogen were evaluated in 95,246 adults aged 40-70 years. Joint exposure to the pollutants was calculated using principal component analysis to create an air pollution score. Subjects were categorized by distance visual acuity into bilateral normal vision, near normal vision, unilateral VI, socially significant VI, and blindness and low vision.</p><p><strong>Results: </strong>A unit rise in air pollution score was associated with 9.2 %, 4.1 %, and 1.8 % increased risks of blindness and low vision, adjusted OR (AOR) = 1.092 (95 % CI, 1.057-1.129); socially significant VI, AOR = 1.041 (95 % CI, 1.016-1.066); and unilateral VI, AOR = 1.018 (95 % CI, 1.007-1.029), respectively. Compared to subjects in the lowest quartile of air pollution score, those in the highest quartile had 69.2 %, 30.5 %, and 9.9 % greater risks of blindness and low vision, AOR = 1.692 (95 % CI, 1.355-2.114), socially significant VI, AOR = 1.305 (95 % CI, 1.127-1.513), and unilateral VI, AOR = 1.099 (95 % CI, 1.035-1.167), respectively while those in the third quartile had 40.5 % and 25.6 % higher risks of blindness and low vision, AOR = 1.405 (95 % CI, 1.121-1.760) and socially significant VI, AOR = 1.256 (95 % CI, 1.086-1.453), respectively. There was a significant trend of increasing risk of blindness and low vision, as well as socially significant VI, as pollution levels rose.</p><p><strong>Conclusion: </strong>Joint exposure to air pollutants increased the risks of poor vision and blindness, suggesting that reducing such exposure could alleviate the disease burden of VI.</p>","PeriodicalId":8594,"journal":{"name":"Asia-Pacific Journal of Ophthalmology","volume":" ","pages":"100209"},"PeriodicalIF":3.7,"publicationDate":"2025-05-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144131845","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Saiko Matsumura, Eva K Fenwick, Momoko Kawakami, Seiji Takagi, Ecosse L Lamoureux, Yuichi Hori
{"title":"Psychometric evaluation of the Japanese version of the Impact of Vision Impairment (IVI) questionnaire using Rasch analysis.","authors":"Saiko Matsumura, Eva K Fenwick, Momoko Kawakami, Seiji Takagi, Ecosse L Lamoureux, Yuichi Hori","doi":"10.1016/j.apjo.2025.100204","DOIUrl":"10.1016/j.apjo.2025.100204","url":null,"abstract":"","PeriodicalId":8594,"journal":{"name":"Asia-Pacific Journal of Ophthalmology","volume":" ","pages":"100204"},"PeriodicalIF":3.7,"publicationDate":"2025-05-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144109489","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Retinal toxicity after intracameral cefuroxime following cataract surgery.","authors":"Xuejuan Cheng, Lu Qiu, Fei Cong, Lei Gao","doi":"10.1016/j.apjo.2025.100206","DOIUrl":"10.1016/j.apjo.2025.100206","url":null,"abstract":"","PeriodicalId":8594,"journal":{"name":"Asia-Pacific Journal of Ophthalmology","volume":" ","pages":"100206"},"PeriodicalIF":3.7,"publicationDate":"2025-05-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143963591","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Wenqing Ye , Shaodan Zhang , Shuqing Zhu , Jinxin Li , Juan Gu , Mian Zhao , Kaiting Jiang , Yanqian Xie , Rongrong Le , Weihe Zhou , Clement C. Tham , Mingguang He , Yuanbo Liang , Ningli Wang
{"title":"24-month prospective randomized comparison of ab externo penetrating canaloplasty versus trabeculectomy in primary angle-closure glaucoma","authors":"Wenqing Ye , Shaodan Zhang , Shuqing Zhu , Jinxin Li , Juan Gu , Mian Zhao , Kaiting Jiang , Yanqian Xie , Rongrong Le , Weihe Zhou , Clement C. Tham , Mingguang He , Yuanbo Liang , Ningli Wang","doi":"10.1016/j.apjo.2025.100167","DOIUrl":"10.1016/j.apjo.2025.100167","url":null,"abstract":"<div><h3>Purpose</h3><div>To report the 24-month efficacy and safety of ab externo penetrating canaloplasty compared with trabeculectomy in the treatment of primary angle-closure glaucoma (PACG).</div></div><div><h3>Methods</h3><div>This is a prospective, randomized, controlled trial. Patients with PACG and inadequately controlled intraocular pressure (IOP) were recruited. Patients enrolled were randomized to either ab externo penetrating canaloplasty (PCP group) or trabeculectomy (TRAB group). The main outcome measures were intraocular pressure (IOP), number of glaucoma medications, success rate and ocular surface disease index (OSDI) questionnaire. Surgical success (definition 1) was defined as 6 mm Hg ≤ IOP ≤ 21 mm Hg with an IOP reduction of ≥ 20 % without glaucoma medications (complete success) or regardless of glaucoma medications (qualified success).</div></div><div><h3>Results</h3><div>A total of 52 eyes (44 patients) were finally enrolled with 25 eyes in PCP group and 27 eyes in TRAB group. PCP group (85.0 %) had a similar qualified success rate compared with TRAB group (87.0 %) with definition 1 at 24 months in intention to treat (ITT) analysis (P = 1.000). In per protocol (PP) analysis, the qualified success with definition 1 were 81.3 % in PCP group and 87.0 % in TRAB group (P = 0.972). But PCP group had a lower success rate in postoperative IOP ≤ 15 mm Hg with an IOP reduction of ≥ 20 % than in TRAB group, in ITT analysis with complete success (PCP 35.0 % vs TRAB 65.2 %, P = 0.048) and PP analysis with qualified success (PCP 31.3 % vs. TRAB 69.6 %, P = 0.025). The mean OSDI score was equal in PCP group (11.9 ± 8.5) and TRAB group (16.6 ± 14.3) (P = 0.302). Hypotony-associated complications were the main complications in PCP group and TRAB group (24.0 % vs. 33.3 %, P = 0.458).</div></div><div><h3>Conclusions</h3><div>Compared with trabeculectomy, ab externo penetrating canaloplasty had a similar qualified success rate and comparable complications at 24 months. Without frequent bleb interventions, penetrating canaloplasty may be a promising surgery for PACG patients especially with early or mild stages.</div></div>","PeriodicalId":8594,"journal":{"name":"Asia-Pacific Journal of Ophthalmology","volume":"14 3","pages":"Article 100167"},"PeriodicalIF":3.7,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143482002","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Association between long-term green space exposure and dry eye in China","authors":"Weijing Cheng , Hanyou Wu , Zhenyu Wang, Lingyi Liang","doi":"10.1016/j.apjo.2025.100165","DOIUrl":"10.1016/j.apjo.2025.100165","url":null,"abstract":"<div><h3>Purpose</h3><div>To evaluate the association between green space exposure and dry eye.</div></div><div><h3>Design</h3><div>Part I: case-control study. Part II: cross-sectional study.</div></div><div><h3>Methods</h3><div>Part I: The study contained 450 patients with dry eye and 900 controls recruited from Electronic Health Records. Logistic regression analysis was employed to investigate the relationship between green space exposure and the occurrence of dry eye. Part II: This study included 140 diabetic participants recruited from the community registry in Guangzhou, China. Linear regression analysis was used to assess the association between green space exposure and quantitative measures of the tear meniscus.</div></div><div><h3>Results</h3><div>Part I: A total of 1350 individuals were included in the study. On average individuals aged 31.07 ± 4.58 years and 59.33 % were female. Higher 10-year green space exposure was significantly associated with lower odds of dry eye (OR = 0.96; 95 % confidence interval [CI], 0.94, 0.97; p < 0.001) after adjusting for age, sex, rainfall, temperature, particulate matter, and other factors. Part II: A total of 140 diabetic patients were included in the study. On average individuals aged 64.48 ± 8.19 years and 53.57 % were female. Greater 10-year green space exposure was associated with a higher tear meniscus area (β = 0.07, 95 % CI, 0.02, 0.11; p = 0.007) after adjusting for age, sex, rainfall, temperature, particulate matter, and other factors.</div></div><div><h3>Conclusions</h3><div>Our findings suggest an association between green space exposure and diagnosis of dry eye and tear meniscus, offering novel insights into the strategies for preventing dry eye.</div></div>","PeriodicalId":8594,"journal":{"name":"Asia-Pacific Journal of Ophthalmology","volume":"14 3","pages":"Article 100165"},"PeriodicalIF":3.7,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143514350","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}