Timothy Y Y Lai, Keiko Kataoka, Yi-Ting Hsieh, Rajendra S Apte, Muna Bhende, Andrew Chang, Voraporn Chiakitmongkol, Youxin Chen, Li Jia Chen, Gemmy C M Cheung, Jay Chhablani, Kenneth C S Fong, Robyn H Guymer, Fumi Gomi, Suber S Huang, Judy E Kim, Gregg T Kokame, Adrian Koh, Xiaoxin Li, Danny S C Ng, Annabelle A Okada, Nishant V Radke, Srinivas R Sadda, Mariko Sasaki, Sobha Sivaprasad, Mahesh P Shanmugam, Lalit Verma, Tien-Yin Wong, Xinyuan Zhang, Dennis S C Lam
{"title":"亚太玻璃体视网膜学会(APVRS)、亚太眼成像学会(APOIS)和亚太眼科教授学会(AAPPO)关于新生血管性年龄相关性黄斑变性(nAMD)的病因、诊断、治疗和未来发展的争议、共识和指南。","authors":"Timothy Y Y Lai, Keiko Kataoka, Yi-Ting Hsieh, Rajendra S Apte, Muna Bhende, Andrew Chang, Voraporn Chiakitmongkol, Youxin Chen, Li Jia Chen, Gemmy C M Cheung, Jay Chhablani, Kenneth C S Fong, Robyn H Guymer, Fumi Gomi, Suber S Huang, Judy E Kim, Gregg T Kokame, Adrian Koh, Xiaoxin Li, Danny S C Ng, Annabelle A Okada, Nishant V Radke, Srinivas R Sadda, Mariko Sasaki, Sobha Sivaprasad, Mahesh P Shanmugam, Lalit Verma, Tien-Yin Wong, Xinyuan Zhang, Dennis S C Lam","doi":"10.1016/j.apjo.2025.100242","DOIUrl":null,"url":null,"abstract":"<p><p>Neovascular age-related degeneration (nAMD) is one of the leading causes of visual impairment in older populations in the developed world. With the aging population, the incidence of nAMD is growing globally. Despite advancements in diagnostic investigations and treatment modalities over the past three decades, there remains considerable controversies in the pathogenesis, classification and optimal management strategies. An international panel of 35 experts from 13 countries/regions prepared and voted on consensus statements in five key areas: 1) etiology controversies; 2) diagnosis controversies; 3) treatment controversies; 4) future development controversies; and 5) healthcare deliveries controversies. Among the 31 consensus statements, 28 (90.3%) have achieved over 75% agreement. These statements can provide a practical guide for ophthalmologists to provide the optimal care of patients with nAMD and for planning future research priorities in order to address the unmet needs in nAMD.</p>","PeriodicalId":8594,"journal":{"name":"Asia-Pacific Journal of Ophthalmology","volume":" ","pages":"100242"},"PeriodicalIF":4.5000,"publicationDate":"2025-08-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Controversies, Consensuses and Guidelines on Etiology, Diagnosis, Treatment, and Future Developments of Neovascular Age-Related Macular Degeneration (nAMD) by the Asia-Pacific Vitreo-retina Society (APVRS), the Asia-Pacific Ocular Imaging Society (APOIS) and the Academy of the Asia-Pacific Professors of Ophthalmology (AAPPO).\",\"authors\":\"Timothy Y Y Lai, Keiko Kataoka, Yi-Ting Hsieh, Rajendra S Apte, Muna Bhende, Andrew Chang, Voraporn Chiakitmongkol, Youxin Chen, Li Jia Chen, Gemmy C M Cheung, Jay Chhablani, Kenneth C S Fong, Robyn H Guymer, Fumi Gomi, Suber S Huang, Judy E Kim, Gregg T Kokame, Adrian Koh, Xiaoxin Li, Danny S C Ng, Annabelle A Okada, Nishant V Radke, Srinivas R Sadda, Mariko Sasaki, Sobha Sivaprasad, Mahesh P Shanmugam, Lalit Verma, Tien-Yin Wong, Xinyuan Zhang, Dennis S C Lam\",\"doi\":\"10.1016/j.apjo.2025.100242\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><p>Neovascular age-related degeneration (nAMD) is one of the leading causes of visual impairment in older populations in the developed world. With the aging population, the incidence of nAMD is growing globally. Despite advancements in diagnostic investigations and treatment modalities over the past three decades, there remains considerable controversies in the pathogenesis, classification and optimal management strategies. An international panel of 35 experts from 13 countries/regions prepared and voted on consensus statements in five key areas: 1) etiology controversies; 2) diagnosis controversies; 3) treatment controversies; 4) future development controversies; and 5) healthcare deliveries controversies. Among the 31 consensus statements, 28 (90.3%) have achieved over 75% agreement. These statements can provide a practical guide for ophthalmologists to provide the optimal care of patients with nAMD and for planning future research priorities in order to address the unmet needs in nAMD.</p>\",\"PeriodicalId\":8594,\"journal\":{\"name\":\"Asia-Pacific Journal of Ophthalmology\",\"volume\":\" \",\"pages\":\"100242\"},\"PeriodicalIF\":4.5000,\"publicationDate\":\"2025-08-29\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Asia-Pacific Journal of Ophthalmology\",\"FirstCategoryId\":\"3\",\"ListUrlMain\":\"https://doi.org/10.1016/j.apjo.2025.100242\",\"RegionNum\":3,\"RegionCategory\":\"医学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q1\",\"JCRName\":\"OPHTHALMOLOGY\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Asia-Pacific Journal of Ophthalmology","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.1016/j.apjo.2025.100242","RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q1","JCRName":"OPHTHALMOLOGY","Score":null,"Total":0}
Controversies, Consensuses and Guidelines on Etiology, Diagnosis, Treatment, and Future Developments of Neovascular Age-Related Macular Degeneration (nAMD) by the Asia-Pacific Vitreo-retina Society (APVRS), the Asia-Pacific Ocular Imaging Society (APOIS) and the Academy of the Asia-Pacific Professors of Ophthalmology (AAPPO).
Neovascular age-related degeneration (nAMD) is one of the leading causes of visual impairment in older populations in the developed world. With the aging population, the incidence of nAMD is growing globally. Despite advancements in diagnostic investigations and treatment modalities over the past three decades, there remains considerable controversies in the pathogenesis, classification and optimal management strategies. An international panel of 35 experts from 13 countries/regions prepared and voted on consensus statements in five key areas: 1) etiology controversies; 2) diagnosis controversies; 3) treatment controversies; 4) future development controversies; and 5) healthcare deliveries controversies. Among the 31 consensus statements, 28 (90.3%) have achieved over 75% agreement. These statements can provide a practical guide for ophthalmologists to provide the optimal care of patients with nAMD and for planning future research priorities in order to address the unmet needs in nAMD.
期刊介绍:
The Asia-Pacific Journal of Ophthalmology, a bimonthly, peer-reviewed online scientific publication, is an official publication of the Asia-Pacific Academy of Ophthalmology (APAO), a supranational organization which is committed to research, training, learning, publication and knowledge and skill transfers in ophthalmology and visual sciences. The Asia-Pacific Journal of Ophthalmology welcomes review articles on currently hot topics, original, previously unpublished manuscripts describing clinical investigations, clinical observations and clinically relevant laboratory investigations, as well as .perspectives containing personal viewpoints on topics with broad interests. Editorials are published by invitation only. Case reports are generally not considered. The Asia-Pacific Journal of Ophthalmology covers 16 subspecialties and is freely circulated among individual members of the APAO’s member societies, which amounts to a potential readership of over 50,000.