发布求助
文献互助 智能选刊 最新文献

Topics in HIV medicine : a publication of the International AIDS Society, USA最新文献

筛选
英文 中文
HIV Vaccine Development. 艾滋病毒疫苗开发。
Topics in HIV medicine : a publication of the International AIDS Society, USA Pub Date : 2009-04-01
David I Watkins
{"title":"HIV Vaccine Development.","authors":"David I Watkins","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Several interesting new vaccine-related studies were presented at the 16th Conference on Retroviruses and Opportunistic Infections this year. Transmitted viruses appear to be derived from cell-free virus rather than cell-associated virus, at least in men who have sex with men. Follow-up studies from the Step (HIV Vaccine Trials Network 502) trial indicated that if individuals mounted certain vaccine-induced responses, they may control viral replication after infection. Finally, adeno-associated-virus-derived neutralizing antibodies completely protected macaques from infection, suggesting novel mechanisms of viral control.</p>","PeriodicalId":85800,"journal":{"name":"Topics in HIV medicine : a publication of the International AIDS Society, USA","volume":"17 2","pages":"35-6"},"PeriodicalIF":0.0,"publicationDate":"2009-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"28212771","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Complications of HIV disease and antiretroviral therapy. 艾滋病毒疾病并发症和抗逆转录病毒治疗。
Topics in HIV medicine : a publication of the International AIDS Society, USA Pub Date : 2009-04-01
Judith S Currier, Diane V Havlir
{"title":"Complications of HIV disease and antiretroviral therapy.","authors":"Judith S Currier,&nbsp;Diane V Havlir","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Continued progress in the diagnosis, management, and prevention of complications of HIV disease and antiretroviral therapy were reported at the 16th Conference on Retroviruses and Opportunistic Infections. This year's conference brought new data on the optimal management of antiretroviral therapy in the presence of different opportunistic infections and included a number of important studies on pathogenesis and epidemiology of long-term complications. Major areas in which new information was presented are highlighted in this article.</p>","PeriodicalId":85800,"journal":{"name":"Topics in HIV medicine : a publication of the International AIDS Society, USA","volume":"17 2","pages":"57-67"},"PeriodicalIF":0.0,"publicationDate":"2009-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"28214491","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Basic science summary. 基础科学总结。
Topics in HIV medicine : a publication of the International AIDS Society, USA Pub Date : 2009-04-01
Mario Stevenson
{"title":"Basic science summary.","authors":"Mario Stevenson","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>The 16th Conference on Retroviruses and Opportunistic Infections featured a strong and balanced program that showcased exciting research into cellular restrictions that defend the cell against viral infection as well as cellular cofactors that regulate central steps in viral replication. Immunopathogenesis presentations continued to reveal some surprises such as evidence for pathogenicity in natural simian immunodeficiency virus infection. The identification of novel cellular restrictions and cellular cofactors of viral replication indicate the possibility of numerous opportunities for the development of novel therapeutic agents for the treatment of HIV and AIDS.</p>","PeriodicalId":85800,"journal":{"name":"Topics in HIV medicine : a publication of the International AIDS Society, USA","volume":"17 2","pages":"30-4"},"PeriodicalIF":0.0,"publicationDate":"2009-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"28212770","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Advances in antiretroviral therapy. 抗逆转录病毒治疗的进展。
Topics in HIV medicine : a publication of the International AIDS Society, USA Pub Date : 2009-04-01
Timothy J Wilkin, Barbara Taylor, Susan Olender, Scott M Hammer
{"title":"Advances in antiretroviral therapy.","authors":"Timothy J Wilkin,&nbsp;Barbara Taylor,&nbsp;Susan Olender,&nbsp;Scott M Hammer","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>The 16th Conference on Retroviruses and Opportunistic Infections maintained its tradition of being recognized as the preeminent forum for detailing the state-of-the-art of antiretroviral therapy. Abundant new and updated information was presented on investigational drugs, approaches to the management of treatment-naive and -experienced patients, the use of drugs for prevention of mother-to-child HIV-1 transmission, and antiretroviral drug resistance. Of particular note were the continued advances in antiretroviral treatment and research emanating from resource-limited settings and the presentation of the results of 2 much-anticipated, phase III trials of interleukin-2, ESPRIT (Evaluation of Subcutaneous Proleukin in a Randomized International Trial) and SILCAAT (Subcutaneous, Recombinant Human Interleukin-2 in HIV-Infected Patients With Low CD4+ Counts Receiving Active Antiretroviral Therapy).</p>","PeriodicalId":85800,"journal":{"name":"Topics in HIV medicine : a publication of the International AIDS Society, USA","volume":"17 2","pages":"68-88"},"PeriodicalIF":0.0,"publicationDate":"2009-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"28214495","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The epidemiology of new HIV infections and interventions to limit HIV transmission. 新发艾滋病毒感染的流行病学和限制艾滋病毒传播的干预措施。
Topics in HIV medicine : a publication of the International AIDS Society, USA Pub Date : 2009-04-01
Susan Buchbinder
{"title":"The epidemiology of new HIV infections and interventions to limit HIV transmission.","authors":"Susan Buchbinder","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>After the disappointing news reported at the 2008 (15th) Conference on Retroviruses and Opportunistic Infections regarding HIV vaccines, microbicides, and herpes virus suppression trials, the 16th conference this year brought welcome advances in the HIV prevention field. In particular, substantial progress is being made in approaches to preexposure prophylaxis in preclinical and clinical trials, and an efficacy trial of a vaginal microbicide appeared to provide women in Africa and the United States with modest protection against HIV acquisition. This review covers presentations on the epidemiology of HIV infection in specific global populations, strategies to improve the uptake of HIV testing, lessons from previous negative prevention trials, and progress in the development of new biomedical interventions.</p>","PeriodicalId":85800,"journal":{"name":"Topics in HIV medicine : a publication of the International AIDS Society, USA","volume":"17 2","pages":"37-43"},"PeriodicalIF":0.0,"publicationDate":"2009-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"28214488","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
HIV infection and travel: pretravel recommendations and health-related risks. 艾滋病毒感染与旅行:旅行前建议和健康相关风险。
Topics in HIV medicine : a publication of the International AIDS Society, USA Pub Date : 2009-02-01
Carlos Franco-Paredes, Alicia Hidron, Ildefonso Tellez, Jeffrey Lesesne, Carlos Del Rio
{"title":"HIV infection and travel: pretravel recommendations and health-related risks.","authors":"Carlos Franco-Paredes,&nbsp;Alicia Hidron,&nbsp;Ildefonso Tellez,&nbsp;Jeffrey Lesesne,&nbsp;Carlos Del Rio","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>In the current era of globalization and ease of air travel combined with the increased survival attained since the advent of potent antiretroviral therapy, HIV-infected individuals are traveling to remote and resource-limited areas of the world. Travel-related health risks in a patient with HIV depend on the patient's immune status, destination, travel itinerary, and type of travel. HIV-infected patients with a CD4+ count of 200 cells/mm3 or lower, particularly those who are treatment-naive and newly diagnosed, are at increased risk of complications when traveling to resource-poor settings. These increased risks include those of acquiring gastrointestinal, respiratory, and endemic tropical infectious diseases. Individuals with a CD4+ count higher than 200 cells/mm3 (whether receiving antiretroviral treatment or not) are considered to have limited immune deficiency for the purpose of travel-related recommendations; in general, they may safely receive most recommended and required vaccines. Pretravel consultation before departure is crucial to address strategies to protect against vaccine-preventable diseases (routine, recommended, and required vaccinations); vector-borne diseases, particularly malaria; gastrointestinal infections; and sexually transmitted diseases. HIV-infected travelers who are ill, particularly those with fever, should undergo an immediate medical evaluation to rule out the possibility of a life-threatening infectious disease such as malaria.</p>","PeriodicalId":85800,"journal":{"name":"Topics in HIV medicine : a publication of the International AIDS Society, USA","volume":"17 1","pages":"2-11"},"PeriodicalIF":0.0,"publicationDate":"2009-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"28030297","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
A review of HIV antiretroviral adherence and intervention studies among HIV-infected youth. 艾滋病毒感染青年抗逆转录病毒依从性和干预研究综述。
Topics in HIV medicine : a publication of the International AIDS Society, USA Pub Date : 2009-02-01
Sari L Reisner, Matthew J Mimiaga, Margie Skeer, Brandon Perkovich, Carey V Johnson, Steven A Safren
{"title":"A review of HIV antiretroviral adherence and intervention studies among HIV-infected youth.","authors":"Sari L Reisner,&nbsp;Matthew J Mimiaga,&nbsp;Margie Skeer,&nbsp;Brandon Perkovich,&nbsp;Carey V Johnson,&nbsp;Steven A Safren","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Advances in antiretroviral medications have resulted in precipitous declines in HIV-associated morbidity and mortality; however, high levels of adherence are crucial to the success of HIV therapies. This article reviews published studies in the United States on HIV-infected youth (ages 13 to 24 years), focusing on adherence to antiretroviral regimens and interventions designed to enhance adherence. A systematic search yielded 21 articles published between 1999 and 2008 that reported data on medication adherence in HIV-infected youth, of which 7 described unique interventions to enhance medication adherence. Five thematic areas were identified to classify factors associated with adherence. Findings suggest psychosocial factors, in particular depression and anxiety, were consistently associated with poorer adherence across studies. Three types of adherence interventions with HIV-infected youth were found. Results suggest that examining adherence within the broader contextual issues present in the lives of youth, including HIV stigma and disclosure, caregiver stress, peer relations, mental health and substance use, and length of time on medications, may be most important to understanding how best to intervene with adherence among this population. Secondary HIV prevention interventions for youth represent a possible mode through which to deliver individually tailored adherence skill building and counseling to improve medication adherence.</p>","PeriodicalId":85800,"journal":{"name":"Topics in HIV medicine : a publication of the International AIDS Society, USA","volume":"17 1","pages":"14-25"},"PeriodicalIF":0.0,"publicationDate":"2009-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3752381/pdf/nihms496536.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"28030232","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
When silence isn't golden. 当沉默不是金。
Topics in HIV medicine : a publication of the International AIDS Society, USA Pub Date : 2009-02-01
Jacqui Scipio-Bannerman
{"title":"When silence isn't golden.","authors":"Jacqui Scipio-Bannerman","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":85800,"journal":{"name":"Topics in HIV medicine : a publication of the International AIDS Society, USA","volume":"17 1","pages":"13"},"PeriodicalIF":0.0,"publicationDate":"2009-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"28030299","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Methicillin-resistant Staphylococcus aureus infections. 耐甲氧西林金黄色葡萄球菌感染。
Topics in HIV medicine : a publication of the International AIDS Society, USA Pub Date : 2008-12-01
John G Bartlett
{"title":"Methicillin-resistant Staphylococcus aureus infections.","authors":"John G Bartlett","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Community-acquired methicillin-resistant Staphylococcus aureus (MRSA) infection is epidemic in the community, differs from nosocomial MRSA in virulence, mechanisms, and antibiotic susceptibility, and exhibits diverse and often unique pathologic characteristics. The community-acquired MRSA USA 300 strains are transmitted largely by person-to-person contact and cause characteristic soft-tissue abscesses and, less commonly, other sometimes unusual and serious infections including a necrotizing pneumonia, and other necrotic infections such as necrotizing fasciitis, pelvic thrombophlebitis, and septic phlebitis. This MRSA 300 family remains susceptible to drugs active against nosocomial MRSA (ie, vancomycin, linezolid, daptomycin) and is often susceptible to trimethoprim-sulfamethoxazole, doxycycline, and clindamycin. Recent epidemiologic data indicate that nosocomial MRSA (eg, mainly USA 100) strains are also present in the community and that MRSA USA 300 strains are present in hospital settings, with both families found in intermediate frequency in health care-associated settings (eg, nursing homes, dialysis centers). More work is needed to identify effective barrier precautions to limit their spread.</p>","PeriodicalId":85800,"journal":{"name":"Topics in HIV medicine : a publication of the International AIDS Society, USA","volume":"16 5","pages":"151-5"},"PeriodicalIF":0.0,"publicationDate":"2008-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"27920856","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Improving engagement in HIV care: what can we do? 改善艾滋病毒护理的参与:我们能做些什么?
Topics in HIV medicine : a publication of the International AIDS Society, USA Pub Date : 2008-12-01
Michael J Mugavero
{"title":"Improving engagement in HIV care: what can we do?","authors":"Michael J Mugavero","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Engagement in HIV care needs to be improved. Important factors to be considered in attempts to improve engagement in care include the following: (1) initial linkage and subsequent retention are distinct processes; (2) engagement in care is vital for HIV treatment success at both the individual and population levels; (3) missed clinic visits can identify patients at high risk for poor health outcomes; (4) engagement in care is worse in groups bearing a disproportionate burden of the domestic HIV epidemic; and (5) ancillary services play a crucial role in improving linkage to and retention in care.</p>","PeriodicalId":85800,"journal":{"name":"Topics in HIV medicine : a publication of the International AIDS Society, USA","volume":"16 5","pages":"156-61"},"PeriodicalIF":0.0,"publicationDate":"2008-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"27920397","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
首页 上一页 下一页 尾页
0
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
提示
您的信息不完整，为了账户安全，请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
现在去查看 取消
×
提示
确定
请完成安全验证×
相关产品
×
本文献相关产品
联系我们：info@booksci.cn Book学术提供免费学术资源搜索服务，方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。 Copyright © 2023 布克学术 All rights reserved.
京ICP备2023020795号-1
ghs 京公网安备 11010802042870号
Book学术文献互助
Book学术文献互助群
群 号：604180095
Book学术官方微信
小红书