Advances in antiretroviral therapy.

Timothy J Wilkin, Barbara Taylor, Susan Olender, Scott M Hammer
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Abstract

The 16th Conference on Retroviruses and Opportunistic Infections maintained its tradition of being recognized as the preeminent forum for detailing the state-of-the-art of antiretroviral therapy. Abundant new and updated information was presented on investigational drugs, approaches to the management of treatment-naive and -experienced patients, the use of drugs for prevention of mother-to-child HIV-1 transmission, and antiretroviral drug resistance. Of particular note were the continued advances in antiretroviral treatment and research emanating from resource-limited settings and the presentation of the results of 2 much-anticipated, phase III trials of interleukin-2, ESPRIT (Evaluation of Subcutaneous Proleukin in a Randomized International Trial) and SILCAAT (Subcutaneous, Recombinant Human Interleukin-2 in HIV-Infected Patients With Low CD4+ Counts Receiving Active Antiretroviral Therapy).

抗逆转录病毒治疗的进展。
第16届逆转录病毒和机会性感染会议保持了其传统,被认为是详细介绍抗逆转录病毒治疗最新进展的卓越论坛。在研究药物、初次治疗和有治疗经验的患者的管理方法、预防HIV-1母婴传播的药物使用以及抗逆转录病毒耐药性等方面提供了大量新的和更新的信息。特别值得注意的是,在资源有限的情况下,抗逆转录病毒治疗和研究的持续进展,以及2项备受期待的白介素-2的III期试验的结果,即ESPRIT(在一项随机国际试验中评估皮下白介素原)和SILCAAT(接受积极抗逆转录病毒治疗的低CD4+计数的hiv感染患者的皮下重组人白介素-2)。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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