Asia-Pacific Journal of Oncology Nursing最新文献

{"title":"Describing the minimally clinically important difference of a chemotherapy-induced peripheral neuropathy patient-reported outcome measure in young adults","authors":"Robert Knoerl ,&nbsp;Emanuele Mazzola ,&nbsp;Lindsay Frazier ,&nbsp;Roy L. Freeman ,&nbsp;Marilyn Hammer ,&nbsp;Ann LaCasce ,&nbsp;Jennifer Ligibel ,&nbsp;Marlise R. Luskin ,&nbsp;Donna Berry","doi":"10.1016/j.apjon.2025.100656","DOIUrl":"10.1016/j.apjon.2025.100656","url":null,"abstract":"<div><h3>Objective</h3><div>The purpose of this secondary analysis was to characterize the reliability, validity, and minimally clinically important difference (MCID) of change scores over time of the European Organisation for Research and Treatment of Cancer Quality of Life Questionnaire-CIPN-20 item (QLQ-CIPN20) in young adults receiving paclitaxel or vincristine.</div></div><div><h3>Methods</h3><div>Fifty young adults receiving vincristine or paclitaxel for the treatment of cancer completed the QLQ-CIPN20 at three time points associated with increasing cumulative chemotherapy dose. The Subject Significance Questionnaire was completed at T3. The analyses were focused on the calculation of floor and ceiling effects, internal consistency reliability, longitudinal validity, construct validity, and the MCID using an anchor-based approach for the QLQ-CIPN20 sensory and motor subscales.</div></div><div><h3>Results</h3><div>By T3, 50% and 52% of participants reported QLQ-CIPN20 sensory and motor subscale scores at the floor, respectively. The internal consistency reliability of the sensory (<em>α</em> ​= ​0.83) and motor (<em>α</em> ​= ​0.89) subscales was strong. The Cohen’s <em>d</em> from T1 to T3 for the QLQ-CIPN20 sensory (<em>d</em> ​= ​−0.57) and motor (<em>d</em> ​= ​−0.47) subscales were small to moderate. There were low to moderate correlations between QLQ-CIPN20 sensory (<em>r</em> ​= ​0.45) and motor (<em>r</em> ​= ​0.27) subscale scores and vincristine cumulative dose. The MCID for worsening QLQ-CIPN20 sensory and motor subscale scores was 14.37 and 9.57, respectively (<em>P</em> ​&lt; ​0.01).</div></div><div><h3>Conclusions</h3><div>Study results provided preliminary evidence surrounding the MCID for worsening of QLQ-CIPN20 scores using an anchor based on young adults' perceived change in CIPN severity. Further research is needed to develop psychometrically sound CIPN patient-reported outcome measures to effectively evaluate the impact of CIPN interventions among young adults.</div></div>","PeriodicalId":8569,"journal":{"name":"Asia-Pacific Journal of Oncology Nursing","volume":"12 ","pages":"Article 100656"},"PeriodicalIF":2.4,"publicationDate":"2025-01-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143348557","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Exploring experiences and needs among children with cancer undergoing peripherally inserted central catheter insertion: A qualitative study","authors":"Chengyang Li ,&nbsp;Chunfeng Wang ,&nbsp;Xueting Zhuang ,&nbsp;Ying Wang ,&nbsp;Yong Wu ,&nbsp;Rong Hu","doi":"10.1016/j.apjon.2025.100654","DOIUrl":"10.1016/j.apjon.2025.100654","url":null,"abstract":"<div><h3>Objective</h3><div>This study aimed to explore the experiences of children with cancer undergoing peripherally inserted central catheter (PICC) insertion.</div></div><div><h3>Methods</h3><div>This study employed a descriptive qualitative approach. A total of 20 children undergoing PICC insertion were enrolled through purposive sampling. Semi-structured interviews, supplemented by draw-and-tell techniques, were conducted to collect data. Thematic analysis method was employed to analyze the interview data.</div></div><div><h3>Results</h3><div>Four themes and 11 subthemes were identified regarding the experience of peripherally inserted central catheter insertion in pediatric cancer patients, including (1) uncertainty (unknown procedure and lack of confidence); (2) high sensitivity (vulnerable to environmental influences and care what others think); (3) psychophysical changes (stress response, physical discomfort, disruption of daily routines, and accepted with pleasure); and (4) multidimensional needs (information, comfort, and self-actualization needs).</div></div><div><h3>Conclusions</h3><div>The findings underscore the importance of gaining a deeper understanding of the symptoms and needs of pediatric cancer patients undergoing PICC insertion. By appreciating and honoring children’s voices, we can effectively cater to their distinct worries and guarantee they get the care and consideration they merit.</div></div>","PeriodicalId":8569,"journal":{"name":"Asia-Pacific Journal of Oncology Nursing","volume":"12 ","pages":"Article 100654"},"PeriodicalIF":2.4,"publicationDate":"2025-01-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143178927","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Decomposition analysis of lung cancer and COPD mortality attributable to ambient PM2.5 in China (1990–2021)","authors":"Xiaoxue Liu ,&nbsp;Haoyun Zhou ,&nbsp;Xun Yi ,&nbsp;Xinyu Zhang ,&nbsp;Yanan Lu ,&nbsp;Wei Zhou ,&nbsp;Yunzhao Ren ,&nbsp;Chuanhua Yu","doi":"10.1016/j.apjon.2025.100653","DOIUrl":"10.1016/j.apjon.2025.100653","url":null,"abstract":"<div><h3>Objective</h3><div>This study aimed to evaluate the long-term trends in lung cancer (LC) and chronic obstructive pulmonary disease (COPD) mortality attributable to particulate matter (PM_2.5) in China and to identify the contributions of population aging and other risk factors to changes in mortality rates.</div></div><div><h3>Methods</h3><div>Using data from 1991 to 2021, we assessed trends in LC and COPD deaths attributable to PM_2.5 through linear regression. Decomposition analysis was conducted to determine the extent to which changes in mortality rates were driven by demographic and non-demographic factors.</div></div><div><h3>Results</h3><div>The crude mortality rates attributable to PM_2.5 increased significantly for LC (500.40%) and COPD (85.26%). From 1990 to 2021, LC mortality attributable to PM_2.5 increased annually by 4.11% (95% CI: 3.64%, 4.59%), while COPD mortality decreased annually by 1.23% (95% CI: −0.82%, −1.65%). Decomposition analysis revealed that 43.0% of the increase in LC mortality was due to population aging, and 57.0% was attributed to changes in other risk factors. For COPD, population aging contributed to an 18.547/100,000 increase, whereas other risk factors reduced mortality by 10.628/100,000.</div></div><div><h3>Conclusions</h3><div>The findings highlight the critical roles of population aging and risk factor modification in LC and COPD mortality trends. Interventions to address aging-related vulnerabilities and air pollution control are essential to mitigate future health burdens.</div></div>","PeriodicalId":8569,"journal":{"name":"Asia-Pacific Journal of Oncology Nursing","volume":"12 ","pages":"Article 100653"},"PeriodicalIF":2.4,"publicationDate":"2025-01-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143379099","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Preliminary testing for affiliate stigma scale: A reliable and valid stigma measure for caregivers of women with breast cancer","authors":"Xiaofan Bu ,&nbsp;Xi Chen ,&nbsp;Lu Luo ,&nbsp;Rongrong Fan ,&nbsp;Ling Jiang ,&nbsp;Xiangyu Liu ,&nbsp;Doris Y.P. Leung","doi":"10.1016/j.apjon.2024.100652","DOIUrl":"10.1016/j.apjon.2024.100652","url":null,"abstract":"<div><h3>Objective</h3><div>Families of breast cancer patients may face discrimination and societal rejection due to prevailing myths, misconceptions and causal beliefs related to breast cancer. This study aims to develop and validate a measurement tool that is sensitive to the affiliate stigma experienced by caregivers of women with breast cancer.</div></div><div><h3>Methods</h3><div>The scale was developed in two phases: (1) item generation based on interviews amongst 18 caregivers of women with breast cancer; (2) psychometric properties of the scale, including content validity, structural validity, and internal consistency reliability. Data were collected from May to June 2023 in 426 caregivers of women with breast cancer from 5 tertiary A hospitals.</div></div><div><h3>Results</h3><div>An exploratory factor analysis produced a 24-item scale across four dimensions, including internal stigma, social isolation, perceived stigma, and reaction. The scale showed good internal consistency and test–retest reliability. The total score of the scale was significantly and positively correlated with scores in caregiving burden and negatively correlated with scores in self-esteem and in social support. The item-level content validity index fell within the range of 0.8–1.0.</div></div><div><h3>Conclusions</h3><div>This is a valid and reliable instrument captured the spectrum of stigma relevant to caregivers of women with breast cancer and may serve as a unique instrument that can be used globally. This study is a step forward for stigma-related studies among caregivers of women with breast cancer and provides a reference for developing effective interventions for those with potentially stigmatized conditions.</div></div>","PeriodicalId":8569,"journal":{"name":"Asia-Pacific Journal of Oncology Nursing","volume":"12 ","pages":"Article 100652"},"PeriodicalIF":2.4,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143386314","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Development and psychometric testing of a self-management scale for cancer survivors with radiotherapy/chemotherapy-induced oral mucositis in China","authors":"Hanfei Cui ,&nbsp;Qingkun Han ,&nbsp;Yulian Wei ,&nbsp;Juan Qiao ,&nbsp;Xiaohong Ji ,&nbsp;Yuanyuan Li ,&nbsp;Xuebing Jing ,&nbsp;Xiaojie Fang","doi":"10.1016/j.apjon.2024.100650","DOIUrl":"10.1016/j.apjon.2024.100650","url":null,"abstract":"<div><h3>Objective</h3><div>This study aims to develop and validate a self-management scale for radiotherapy/chemotherapy-induced oral mucositis (SMS-RIOM/CIOM) in cancer survivors, addressing the need for a comprehensive tool to assess self-management capabilities.</div></div><div><h3>Methods</h3><div>This study employed a two-phase process: (1) initial scale development through literature review, semi-structured interviews, and expert consultations, and (2) psychometric testing with 420 cancer survivors from five wards of Zibo Hospital. The psychometric evaluation included item analysis, content validity testing, reliability assessments, exploratory factor analysis (EFA), and confirmatory factor analysis (CFA).</div></div><div><h3>Results</h3><div>The finalized SMS-RIOM/CIOM consists of 15 items across four dimensions: medication management, oral pain management, disease monitoring, and daily life management. EFA explained 77.322% of the total variance, while CFA demonstrated an excellent model fit (χ²/df=1.909, RMSEA=0.064, RMR=0.052, GFI=0.911, CFI=0.964, NFI=0.928, TLI=0.955, IFI=0.964). Reliability metrics were robust, including Cronbach's alpha of 0.902, split-half reliability of 0.849, test-retest reliability of 0.862, and a scale content validity index of 0.910.</div></div><div><h3>Conclusions</h3><div>The SMS-RIOM/CIOM is a reliable and valid tool for assessing self-management in cancer survivors with RIOM/CIOM. It provides valuable insights for clinical practice, enabling targeted interventions to improve self-management and enhance the quality of life for cancer survivors. Further research is recommended to validate its application across diverse populations and healthcare settings.</div></div>","PeriodicalId":8569,"journal":{"name":"Asia-Pacific Journal of Oncology Nursing","volume":"12 ","pages":"Article 100650"},"PeriodicalIF":2.4,"publicationDate":"2024-12-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11786852/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143078493","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Latent profile analysis of fear of cancer recurrence in patients with prostate cancer: Insights into risk factors and psychological interventions","authors":"Ziyi Qi ,&nbsp;Yun Dai ,&nbsp;Sijia Hou ,&nbsp;Binbin Zhu ,&nbsp;Wei Wang","doi":"10.1016/j.apjon.2024.100651","DOIUrl":"10.1016/j.apjon.2024.100651","url":null,"abstract":"<div><h3>Objective</h3><div>To explore fear of cancer recurrence (FCR) profiles in prostate cancer survivors, identify heterogeneous subgroups, and examine influencing factors to provide a reference for improving mental well-being and overall quality of life.</div></div><div><h3>Methods</h3><div>A convenience sample of 389 patients completed a questionnaire that assessed general and disease-related data, including the Fear of Progression Questionnaire-Short Form, Perceived Social Support Scale, European Organization for Research and Treatment of Cancer Quality of Life Questionnaire-Core 30. Statistical analysis involved latent profile analysis (LPA), Bolck-Croon-Hagenaars methods and multinomial logistic regression.</div></div><div><h3>Results</h3><div>Three FCR profiles were identified: “Adapted” (25.7%), “Struggling” (42.2%), and “Dysregulated” (32.1%). Compared to the Adapted group, factors associated with the Struggling group included age, social support, and employment status, while factors associated with the Dysregulated group included age, social support, and time since diagnosis. From Adapted to Dysregulated, physical, cognitive, emotional, and social function declined, while dyspnea, insomnia, and financial difficulties increased.</div></div><div><h3>Conclusions</h3><div>The psychological problems caused by the FCR in patients with prostate cancer seriously affect their physical, emotional, cognitive and social functions. Targeted intervention strategies should be developed for different categories of patients with prostate cancer to improve the FCR and promote the health-related quality of life.</div></div>","PeriodicalId":8569,"journal":{"name":"Asia-Pacific Journal of Oncology Nursing","volume":"12 ","pages":"Article 100651"},"PeriodicalIF":2.4,"publicationDate":"2024-12-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143356661","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Symptoms associated with concurrent chemoradiotherapy in patients with cervical cancer: Application of latent profile analysis and network analysis","authors":"Xiangyu Lu ,&nbsp;Lingling Zheng ,&nbsp;Xue Jin ,&nbsp;Yuejia Wang ,&nbsp;Shengwu Wu ,&nbsp;Yin Lv ,&nbsp;Hua Du","doi":"10.1016/j.apjon.2024.100649","DOIUrl":"10.1016/j.apjon.2024.100649","url":null,"abstract":"<div><h3>Objective</h3><div>This study aims to explore symptom subgroups and influencing factors among patients undergoing concurrent chemoradiotherapy (CCRT) for cervical cancer, to construct a symptom network, and to identify core symptoms within the overall sample and its various subgroups.</div></div><div><h3>Methods</h3><div>A cross-sectional survey was conducted with 378 patients undergoing CCRT for cervical cancer from June 2023 to May 2024 at a tertiary hospital in Anhui Province. Participants completed the General Information Questionnaire, the Symptom Assessment Scale for Patients Undergoing CCRT for Intermediate and Advanced Cervical Cancer, and the Dyadic Coping Inventory. Latent profile analysis (LPA) identified symptom subgroups, while multivariate logistic regression examined influences on these subgroups. Symptom networks were developed using R language to analyze centrality indices and identify core symptoms.</div></div><div><h3>Results</h3><div>Patients were classified into three subgroups: low symptom burden (<em>n</em> ​= ​200, 52.91%), moderate symptom burden with prominent intestinal response (<em>n</em> ​= ​75, 19.84%), and high symptom burden (<em>n</em> ​= ​103, 27.25%). Multivariate logistic regression indicated that age, tumor stage, chemotherapy frequency, and dyadic coping (DC) were predictive of subgroup membership (<em>P</em> ​&lt; ​0.05). Network analysis revealed sadness (<em>r</em>_<em>s</em> ​= ​1.320) as the core symptom for the overall sample, nausea (<em>r</em>_<em>s</em> ​= ​0.801) for the low symptom burden group, and vomiting (<em>r</em>_<em>s</em> ​= ​0.705, 0.796) for both the moderate symptom burden with intestinal response prominence group and the high symptom burden group.</div></div><div><h3>Conclusions</h3><div>Three symptom subgroups exist among patients undergoing CCRT for cervical cancer, with sadness, nausea, and vomiting identified as core symptoms. Health care professionals should provide individualized symptom management tailored to these subgroups.</div></div>","PeriodicalId":8569,"journal":{"name":"Asia-Pacific Journal of Oncology Nursing","volume":"12 ","pages":"Article 100649"},"PeriodicalIF":2.4,"publicationDate":"2024-12-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11786907/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143078499","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Best evidence for rehabilitation management of urinary incontinence in patients with bladder cancer following orthotopic neobladder reconstruction","authors":"Man Xu ,&nbsp;Shuhong Chen ,&nbsp;Xiyuan Liu ,&nbsp;Yuyi Luo ,&nbsp;Di Wang ,&nbsp;Huiming Lu ,&nbsp;Mengxiao Jiang ,&nbsp;Xiaoping Chen","doi":"10.1016/j.apjon.2024.100647","DOIUrl":"10.1016/j.apjon.2024.100647","url":null,"abstract":"<div><h3>Objective</h3><div>This study aims to establish the best evidence for the rehabilitation management of urinary incontinence (UI) in patients with orthotopic neobladder (ONB) following radical cystectomy (RC) for bladder cancer, providing a theoretical foundation for clinical practice.</div></div><div><h3>Methods</h3><div>A systematic search was conducted across evidence-based databases, guideline networks, and professional association websites to identify relevant literature on rehabilitation management for patients with ONB after bladder cancer surgery. Studies published in both English and Chinese, up to May 8, 2024, were included. Trained researchers assessed the quality of the literature and summarized the evidence.</div></div><div><h3>Results</h3><div>Fourteen documents were included, consisting of eight guidelines, two clinical decision documents, and four expert consensus reports. A total of 43 pieces of evidence were identified, covering seven key areas: preoperative UI assessment and counseling, preventive measures, UI assessment and diagnosis, conservative treatments, selection and use of nursing equipment, evaluation of effectiveness, and follow-up care.</div></div><div><h3>Conclusions</h3><div>The best evidence for UI rehabilitation management after ONB for bladder cancer can help standardize patient care and clinical practices. Healthcare providers should adapt this evidence to their local healthcare settings, cultural contexts, barriers, and patient preferences.</div></div><div><h3>Systematic review registration</h3><div>This study was conducted following the evidence summary reporting specifications of the Fudan University Center for Evidence-Based Nursing (Registration No. ES20244165).</div></div>","PeriodicalId":8569,"journal":{"name":"Asia-Pacific Journal of Oncology Nursing","volume":"12 ","pages":"Article 100647"},"PeriodicalIF":2.4,"publicationDate":"2024-12-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11782885/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143078490","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The role of a cardio-oncology clinical nurse specialist in the United Kingdom","authors":"Priya Reehal ,&nbsp;Alexander R. Lyon ,&nbsp;Geraldine Lee","doi":"10.1016/j.apjon.2024.100640","DOIUrl":"10.1016/j.apjon.2024.100640","url":null,"abstract":"<div><div>Cardio-oncology is a growing subspeciality of cardiology that involves the prevention and early detection of cancer therapy-related cardiovascular toxicity (CTR-CVT). Cardiovascular complications can occur before, during and after cancer treatment, due to de novo cardiotoxicity or an exacerbation of a previous cardiac condition. Therefore, cancer patients undergoing cancer treatment need to be assessed before, during and after their cancer treatment. This article describes the development and progress of a specialised nursing role, known as a Clinical Nurse Specialist (CNS), at the Royal Brompton Hospital in London, United Kingdom (UK).</div></div>","PeriodicalId":8569,"journal":{"name":"Asia-Pacific Journal of Oncology Nursing","volume":"12 ","pages":"Article 100640"},"PeriodicalIF":2.4,"publicationDate":"2024-12-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143178509","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Identifying the heterogeneity of self-advocacy in Chinese patients with breast cancer using latent profile analysis and symptom networks","authors":"Liping Teng ,&nbsp;Yajun Dong ,&nbsp;Yiting Yang ,&nbsp;Zhou Zhou ,&nbsp;Jun Sun ,&nbsp;Teng Wang","doi":"10.1016/j.apjon.2024.100648","DOIUrl":"10.1016/j.apjon.2024.100648","url":null,"abstract":"<div><h3>Objective</h3><div>This study aims to identify subgroups of self-advocacy in patients with breast cancer, assess the heterogeneity among different subgroups, and further delineate symptom networks within each subgroup.</div></div><div><h3>Methods</h3><div>A cross-sectional survey was conducted among 320 patients with breast cancer in Wuxi, China, from September 2023 to March 2024, who completed questionnaires about their demographic and clinical characteristics, the M.D. Anderson Symptom Inventory, and the Female Self Advocacy in Cancer Survivorship scale. Latent profile analysis was conducted to identify subgroups of self-advocacy. Multinomial logistic regression was employed to reveal the heterogeneity of each subgroup in demographics and clinical characteristics. Network analysis was performed to unveil the network structure of clinical symptoms within each subgroup.</div></div><div><h3>Results</h3><div>Three subgroups were identified: “Profile 1: low self-advocacy”, “Profile 2: moderate self-advocacy”, and “Profile 3: high self-advocacy”. Compared with patients in Profile 3, those in Profile 1 and Profile 2 showed a higher tendency to have more severe symptoms. Network analysis further revealed that “lack of appetite” emerged as the core symptom in Profile 1, while the core symptom in Profile 2 and Profile 3 was “distress”.</div></div><div><h3>Conclusions</h3><div>Patients in different subgroups manifest individualized self-advocacy. The severity of clinical symptoms might serve as an important risk factor for those with low levels of self-advocacy. Conducting symptom networks of diverse subgroups can facilitate tailored symptom management by focusing on core symptoms, thereby enhancing the effectiveness of interventions and improving patients’ self-advocacy and overall quality of life.</div></div>","PeriodicalId":8569,"journal":{"name":"Asia-Pacific Journal of Oncology Nursing","volume":"12 ","pages":"Article 100648"},"PeriodicalIF":2.4,"publicationDate":"2024-12-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11783386/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143078496","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}