Asian Pacific Journal of Reproduction最新文献

{"title":"An incidental presentation of Herlyn–Werner-Wunderlich syndrome with secondary infertility: A case report","authors":"Abiola O. Adekoya, A. Akiseku, A. Olatunji, M. Olusola-Bello","doi":"10.4103/2305-0500.356844","DOIUrl":"https://doi.org/10.4103/2305-0500.356844","url":null,"abstract":"Rationale: Herlyn-Werner-Wunderlich syndrome, also known as obstructed hemi-vagina with ipsilateral renal agenesis (OHVIRA) syndrome, is a rare congenital anomaly of the Müllerian and Wolffian ducts. It is often asymptomatic until puberty and is usually misdiagnosed as infertility. Patient concerns: A 39-year-old woman desirous of pregnancy was referred to our radiodiagnosis unit for imaging evaluation on account of secondary infertility. Diagnosis: Incidental discovery of uterine bicornis bicollis and blind-ending hemivagina was noted at hysterosalpingography. Interventions: This necessitated the search for other genitourinary tract anomalies, and ipsilateral renal agenesis was also discovered. Outcomes: A diagnosis of Herlyn-Werner-Wunderlich syndrome was made. Lessons: Magnetic resonance imaging (MRI) is considered the gold standard imaging modality for the assessment of uterine malformations. However, in resource-poor centers where MRI is unavailable, a heightened clinical suspicion with the combination of available imaging modalities is important and reliable in making an accurate diagnosis, hence, successful management.","PeriodicalId":8564,"journal":{"name":"Asian Pacific Journal of Reproduction","volume":"11 1","pages":"243 - 246"},"PeriodicalIF":0.0,"publicationDate":"2022-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44869267","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"L–carnitine improves developmental competence of buffalo oocytes in vitro","authors":"A. Modak, M. Islam, A. Khatun, M. Alam, I. Akter, A. Kabir, M. Hashem, M. Moniruzzaman","doi":"10.4103/2305-0500.356843","DOIUrl":"https://doi.org/10.4103/2305-0500.356843","url":null,"abstract":"Objective: To investigate the effect of L-carnitine on in vitro maturation and subsequent in vitro embryo production of buffalo oocytes. Methods: Cumulus oocyte complexes (COCs) were aspirated from ovaries of slaughtered buffaloes. COCs were classified into good and fair qualities based on morphological observation of numbers and integrity of cumulus cells surrounding the oocyte. Both categories of COCs were placed in in vitro maturation medium with supplementation of different concentrations (0, 0.250, 0.375 or 0.500 mg/mL) of L-carnitine. Oocytes from both qualities were in vitro fertilized and in vitro cultured for 7 days, to examine the developmental competence. Results: Supplementation of L-carnitine to in vitro maturation medium increased the cumulus cell expansion rate of COCs to grade A, and reduced the cumulus cell expansion of COCs to grade B and grade C in both good and fair quality oocytes. Similarly, L-carnitine induced the in vitro meiotic progression of buffalo oocytes to metaphase Π in both good and fair quality oocytes. Additionally, L-carnitine reduced the rate of oocyte degeneration in both good and fair quality oocytes. L-carnitine increased the rate of cleaved formation at day 2 and blastocyst formation at day 7 during in vitro culture in both qualities of oocytes. Moreover, a higher rate of blastocyst production was observed in L-carnitine-treated fair quality oocytes, which was higher than the results in the untreated good quality oocytes. Conclusions: L-carnitine enhances meiotic maturation and subsequent embryo development from both good and fair quality buffalo oocytes.","PeriodicalId":8564,"journal":{"name":"Asian Pacific Journal of Reproduction","volume":"11 1","pages":"236 - 242"},"PeriodicalIF":0.0,"publicationDate":"2022-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49323858","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Evaluation of intratesticular chlorhexidine gluconate for chemical contraception in dogs","authors":"Aeknath Virendra, O. Shrivastava, S. Shukla, M. Shukla, N. Bajaj, Afroza Khanam, F. Khan","doi":"10.4103/2305-0500.356842","DOIUrl":"https://doi.org/10.4103/2305-0500.356842","url":null,"abstract":"Objective: To investigate the contraceptive effect of intratesticular injection of chlorhexidine gluconate in dogs and compare it with that of zinc gluconate neutralized with arginine. Methods: Twenty-four sexually mature male mongrel dogs were randomly divided by replicate into four groups (n=6 per group). Group I received intra-testicular injection of 2 mL zinc gluconate (10 mg/mL) neutralized with arginine. Group II received intratesticular injection of 2 mL chlorhexidine gluconate (5% w/v). Group Ⅲ received intratesticular injection of 2 mL chlorhexidine gluconate (4% w/v). Group Ⅳ did not receive any treatment and served as the control group. Testicular morphometry was conducted on day 0, 7, 15 and 30 after treatment. Semen was collected and evaluated on day 0 and 30. Data were analyzed using repeated measures analysis of variance. Results: There was no difference in the mean values of various parameters between dogs treated with zinc gluconate and those treated with chlorhexidine gluconate at any of the time points. In dogs treated with zinc gluconate or chlorhexidine gluconate, there was a significant increase in the testicular morphometric parameters on day 7 followed by a significant reduction thereafter (day 15 and 30). In contrast, there was no change in any of the parameters in the control untreated dogs during the course of the study. Compared to the pre-treatment values, the mean scrotal circumference and the mean paired testicular volume and testicular weight on day 30 were significantly lower in the treated dogs. Semen samples collected on day 30 from treated dogs were found to be azoospermic, whereas no change in semen quality was observed in the control untreated dogs. Conclusions: Intratesticular injection of chlorhexidine gluconate (5% w/v and 4% w/v) is equally as effective as zinc gluconate neutralized with arginine for chemical contraception in dogs.","PeriodicalId":8564,"journal":{"name":"Asian Pacific Journal of Reproduction","volume":"11 1","pages":"231 - 235"},"PeriodicalIF":0.0,"publicationDate":"2022-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47809637","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Impact of gamete health on fertilization and embryo development: An overview","authors":"Jaypalsinh Chorya, T. Sutaria, R. Chaudhari, C. Chaudhari","doi":"10.4103/2305-0500.356838","DOIUrl":"https://doi.org/10.4103/2305-0500.356838","url":null,"abstract":"A genetically and functionally proficient gamete is essential for normal fertilization and embryonic development. Any change in gamete health affects fertilization and subsequent events, including embryonic development, implantation, and successful pregnancy. This present review focuses on the role of gamete health on fertilization and embryo development. Several conventional and advanced methods are used to evaluate the morphology and functions of gametes. The abnormal spermatozoa adversely affect fertilization events, which results in reduced cleavage/blastocyst/ implantation and pregnancy rate during assisted reproductive techniques. Poor oocyte quality is also one of the reasons for infertility, although the oocyte has an innate capacity to repair a certain amount of abnormality of both oocyte and spermatozoa. Therefore, oocyte health carries more responsibilities during fertilization events. The gamete, either spermatozoa or oocyte, should have optimum morphological and functional health to fertilize and develop a competent embryo successfully. Thus, it is of prime importance to consider the gamete health parameters while dealing with infertility.","PeriodicalId":8564,"journal":{"name":"Asian Pacific Journal of Reproduction","volume":"11 1","pages":"201 - 207"},"PeriodicalIF":0.0,"publicationDate":"2022-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43758065","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Assisted reproduction in the COVID-19 era: Dilemmas and conundrums","authors":"R. Baid","doi":"10.4103/2305-0500.350148","DOIUrl":"https://doi.org/10.4103/2305-0500.350148","url":null,"abstract":"","PeriodicalId":8564,"journal":{"name":"Asian Pacific Journal of Reproduction","volume":"11 1","pages":"153 - 154"},"PeriodicalIF":0.0,"publicationDate":"2022-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43635413","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Reproductive health and rights in the COVID-19 era: Why and how are rights and choices still the answer?","authors":"M. Hossain","doi":"10.4103/2305-0500.350149","DOIUrl":"https://doi.org/10.4103/2305-0500.350149","url":null,"abstract":"","PeriodicalId":8564,"journal":{"name":"Asian Pacific Journal of Reproduction","volume":"11 1","pages":"155 - 157"},"PeriodicalIF":0.0,"publicationDate":"2022-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47350266","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Iron supplementation for non-anaemic pregnant women and the incidence of hypertensive disorders in pregnancy: A systematic review and meta-analysis","authors":"Farida Fitriana, P. Pallotti","doi":"10.4103/2305-0500.350152","DOIUrl":"https://doi.org/10.4103/2305-0500.350152","url":null,"abstract":"Objective: To investigate effect of iron supplementation on the risk of hypertensive disorders in pregnancy in non-anaemic pregnant women. Methods: A literature search was conducted using three categories of terms with its synonyms or related words: “iron”, “supplement”, “hypertensive disorders in pregnancy” through MEDLINE (OVID), CINAHL, PubMed, Cochrane Library, Scopus, Web of Science, ICTRP, and ClinicalTrials.gov, and manual search of references was used in seven potential resources. The inclusion criteria were randomized control trials (RCTs), published in English, full-text available, having healthy pregnant women without anaemia for study participants, and having hypertensive disorders in pregnancy at the end of pregnancy as the outcome. The risk of bias assessment tool was used for quality appraisal. Meta-analysis was conducted by calculating the fixed and random effects of the odds ratio (OR) for iron supplementation among non-anaemic pregnant women compared with the incidence of hypertensive disorders in pregnancy. The range of the study’s estimation accuracy was reflected by a 95% confidence interval (CI). Results: Four RCTs were included in the meta-analysis. The pooled results showed that iron supplementation possibly had no effect on the incidence of hypertensive disorders in pregnancy (OR 0.93, 95% CI 0.81-1.07; P=0.30), gestational hypertension (OR 1.37, 95% CI 0.69-2.73; P=0.36) as well as on the development of preeclampsia (OR 1.45, 95% CI 0.71-2.97; P=0.31). Conclusions: Iron supplementation has no effect on the incidence of hypertension in non-anaemic pregnant women. In general, there is a lack of evidence for the association between iron supplementation and the incidence of hypertensive disorders in pregnancy among non-anaemic pregnant women, and further studies are needed.","PeriodicalId":8564,"journal":{"name":"Asian Pacific Journal of Reproduction","volume":"11 1","pages":"165 - 174"},"PeriodicalIF":0.0,"publicationDate":"2022-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41711854","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Testicular vascularization at two locations in relation to hormonal levels, and pixel echotexture in bulls at different ages","authors":"E. Abdelnaby, I. Emam","doi":"10.4103/2305-0500.350155","DOIUrl":"https://doi.org/10.4103/2305-0500.350155","url":null,"abstract":"Objective: To assess the hemodynamic changes that occurred in the main testicular artery at two different locations such as supra and marginal ones in bulls at three different ages. Methods: Eighteen Baladi bulls were divided according to their age into three different age groups: 1 year [n=6; group I with bodyweight (380±10) kg], 3 years [n=6; group II with bodyweight (570±10) kg], and 6 years old [n=6; group III with bodyweight (650±10) kg] Baladi bulls. Circumference of the scrotum, thickness of the mediastinum, testicular dimensions, vascularity, and hormonal levels were measured. Testicular hemodynamics were assessed by Doppler ultrasound scanning. Results: Testicular width, length, and volume were significantly different among the three age groups, with the highest in bulls of group III (P<0.05). The bulls in group III had significantly higher mediastinal line thickness and scrotal circumference than group I (P<0.05), but there was no significant difference between group II and group III. Bulls in group II showed a decline in Doppler indices (resistance and pulsatility indexes) at both testicular branches compared to the other two groups (P<0.05). Supra and marginal end diastolic velocities in the three age groups were significantly different, with the highest in group II (P<0.05). Time average velocity (cm/s) was significantly elevated in group II compared to the other two groups (P<0.05). Both testicular echotextures were significantly decreased in group II (P<0.05). Estradiol and nitric oxide metabolites were significantly high in group II compared to the other two groups (P<0.05). Meanwhile, the level of plasma testosterone was maximum in group III (P<0.05). Positive correlations were found between supratesticular artery resistance and pulsatility indexes (r=0.81; P<0.001), while both resistance and pulsatility indexes had correlated negative with estradiol (r=-0.71 and r=-0.91; P<0.001), and nitric oxide metabolites (r=-0.92 and r=-0.72; P<0.001). Conclusions: Three-year old Baladi bull has the lesser Doppler indices with lesser echotexture and greater nitric oxide with estradiol concentrations, which directs a significant ability for the thermoregulation process. These parameters will help in breeding selection.","PeriodicalId":8564,"journal":{"name":"Asian Pacific Journal of Reproduction","volume":"11 1","pages":"193 - 200"},"PeriodicalIF":0.0,"publicationDate":"2022-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49159086","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Impact of geographical and seasonal temperature on sperm parameters in Indian men who were partners in subfertile couples – A retrospective analysis","authors":"Y. Dogra, N. Singh, N. Malhotra, R. Mahey, V. Perumal","doi":"10.4103/2305-0500.350153","DOIUrl":"https://doi.org/10.4103/2305-0500.350153","url":null,"abstract":"Objective: To evaluate the impact of seasonal and geographical temperature on sperm parameters in Indian men who were partners in subfertile couples. Methods: A retrospective review of the records of semen analysis from January 2009 to December 2017 that was performed as part of primary evaluation of infertile couple was undertaken. Mean values of various semen parameters were compared between seasons using one-way analysis of variance test followed by Bonferroni pair wise post-hoc comparison test. Bivariate Pearson correlation coefficient was applied to measure the correlation between age, sperm parameters and annual temperature/seasons. The logistic regression analysis was further carried out to identify significant variables contributing to normal progressive motility of sperm. Results: A total of 3 433 reports of semen samples were analysed. There was no significant seasonal variation in the mean volume, concentration, and total motility levels (P>0.05) except the mean values of progressive motility (P<0.001). The mean values of progressive motility during pre-monsoon were significantly higher compared to the corresponding values during monsoon and autumn seasons (P<0.01). In all the seasons, total motility had significant positive correlation with sperm concentration and progressive motility (P<0.05). Pre-monsoon emerged as the significant favourable season to get normal progressive motility level (OR 1.32, 95% CI 1.04-1.68) compared to winter. The chances of getting normal progressive motility reduced due to longer abstinence period (OR 0.87, 95% CI 0.80-0.93). When the temperature was more than 28 °C, the likelihood of getting normal progressive motility decreased (OR 0.70, 95% CI 0.51-0.95). Conclusions: The progressive motility of sperms significantly decreases from pre-monsoon to autumn with recovery towards winter, which substantiates the effect of rising temperature on the progressive motility of sperm. This is clinically important to counsel infertile patients, so that they can plan their treatment accordingly.","PeriodicalId":8564,"journal":{"name":"Asian Pacific Journal of Reproduction","volume":"11 1","pages":"175 - 182"},"PeriodicalIF":0.0,"publicationDate":"2022-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43178749","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Season modulates endocrinological profiles and sex behavioural characteristics in indigenous male goats under tropical humid island ecosystem","authors":"Perumal Ponraj, J. Sunder, A. De, R. Alyethodi, P. Mishra, S. Bhowmick, D. Bhattacharya","doi":"10.4103/2305-0500.350154","DOIUrl":"https://doi.org/10.4103/2305-0500.350154","url":null,"abstract":"Objective: To measure the seasonal effect on endocrinological profiles and sex behavioural profiles during rainy and dry summer seasons in male Andaman local goat in Andaman and Nicobar Islands, India. Methods: Ten adult male Andaman local goats were selected from the goat breeding farm, ICAR-Central Island Agricultural Research Institute, Port Blair, Andaman and Nicobar Islands, India. Endocrinological profiles such as follicle stimulating hormone (FSH), luteinizing hormone (LH), testosterone, thyroid stimulating hormone (TSH), triiodothyronine (T3), thyroxine (T4), cortisol and prolactin were analysed with enzyme-linked immunosorbent assay kits. Sex behavioural profiles such as libido score, mating ability score and sex behavioural score were measured during rainy and dry summer seasons in male Andaman local goat. Results: Endocrinological profiles as well as sex behavioural profiles differed significantly between rainy season and dry summer season (P<0.05). The levels of FSH, LH, testosterone, TSH, T3, and T4 were significantly higher in rainy season than in dry summer season whereas cortisol and prolactin were significantly higher in dry summer season than in rainy season (P<0.05). The ratio of T3:T4 was significantly higher in rainy season than in dry summer season. Similarly, libido score, mating ability score and sex behavioural score were significantly higher in rainy season than in dry summer season (P<0.05). Conclusions: Rainy season has significantly higher beneficial effects than summer season on reproduction and artificial breeding programmes in semi-intensive management of goat under the tropical humid island ecosystem in Andaman and Nicobar Islands.","PeriodicalId":8564,"journal":{"name":"Asian Pacific Journal of Reproduction","volume":"11 1","pages":"183 - 192"},"PeriodicalIF":0.0,"publicationDate":"2022-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41735228","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}