Asian Pacific Journal of Reproduction最新文献_第6页

Conventional treatment options and herbal remedies for male infertility: An overview 男性不育的常规治疗选择和草药疗法：综述

Asian Pacific Journal of Reproduction Pub Date : 2022-07-01 DOI: 10.4103/2305-0500.350150

A. Wal, P. Wal, Ashutosh Pandey, Himangi Vig, R. Karunakaran, B. Dash

引用次数: 1

Investigation of FOXP3 (rs3761548) polymorphism with the risk of preeclampsia and recurrent spontaneous abortion: A systemic review and meta-analysis FOXP3 (rs3761548)多态性与子痫前期和复发性自然流产风险的研究:一项系统回顾和荟萃分析

Asian Pacific Journal of Reproduction Pub Date : 2022-05-01 DOI: 10.4103/2305-0500.346089

Govinda Varshini, Sivakumar Harshini, Muhammed Siham, Govindaraj Tejaswini, Yasam Kumar, Langeswaran Kulanthaivel, G. Subbaraj

{"title":"Investigation of FOXP3 (rs3761548) polymorphism with the risk of preeclampsia and recurrent spontaneous abortion: A systemic review and meta-analysis","authors":"Govinda Varshini, Sivakumar Harshini, Muhammed Siham, Govindaraj Tejaswini, Yasam Kumar, Langeswaran Kulanthaivel, G. Subbaraj","doi":"10.4103/2305-0500.346089","DOIUrl":"https://doi.org/10.4103/2305-0500.346089","url":null,"abstract":"Objective: To investigate the association between forkhead box P3 (FOXP3) (rs3761548) polymorphism and the risk of preeclampsia and recurrent spontaneous abortion. Methods: Literature on the association of FOXP3 gene polymorphisms and susceptibility to preeclampsia and unexplained recurrent spontaneous abortion was retrieved by searching databases such as PubMed, Science Direct, Google Scholar and Embase from 2000 to 2021. The association measure was analyzed using an odds ratio (OR) and 95% confidence interval (CI). All the statistical analyses were executed using RevMan 5.4 software. Results: In the present meta-analysis, 11 articles were analyzed. The pooled results showed no association between FOXP3 gene polymorphism (rs3761548) and preeclampsia risk in allelic, recessive, dominant and over dominant contrast models. FOXP3 gene polymorphism (rs3761548) showed an association with recurrent abortion in allelic, recessive and dominant models (OR 1.85, CI 1.59-2.14; OR 2.02, 95% CI 1.56-2.62; OR 2.69, 95% CI 1.50-4.83, respectively), while no association in the over dominant contrast model (OR 1.35, CI 0.87-2.10). Conclusions: In the present study, FOXP3 gene (rs3761548) polymorphism is associated with risk of recurrent spontaneous abortion but not preeclampsia. However, larger sample size and multiracial studies are needed in the future to confirm the findings.","PeriodicalId":8564,"journal":{"name":"Asian Pacific Journal of Reproduction","volume":"11 1","pages":"117 - 124"},"PeriodicalIF":0.0,"publicationDate":"2022-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41968753","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 2

Sjögren's syndrome and reproductive outcomes Sjögren综合症和生殖结果

Asian Pacific Journal of Reproduction Pub Date : 2022-05-01 DOI: 10.4103/2305-0500.346087

Greeshma Sree Nayudu, Arjun Nambiar, K. Moudgil

引用次数: 0

Sperm DNA fragmentation does not affect the clinical outcomes in the cumulative transfers of an ICSI cycle along with blastocyst transfers in couples with normozoospermic male patients 精子DNA断裂不会影响正常精子男性患者夫妇ICSI周期累积转移和胚泡转移的临床结果

Asian Pacific Journal of Reproduction Pub Date : 2022-05-01 DOI: 10.4103/2305-0500.346090

Deepthi Repalle, K. Saritha, Shilpa Bhandari

{"title":"Sperm DNA fragmentation does not affect the clinical outcomes in the cumulative transfers of an ICSI cycle along with blastocyst transfers in couples with normozoospermic male patients","authors":"Deepthi Repalle, K. Saritha, Shilpa Bhandari","doi":"10.4103/2305-0500.346090","DOIUrl":"https://doi.org/10.4103/2305-0500.346090","url":null,"abstract":"Objective: To know whether sperm DNA fragmentation (SDF) affects the clinical outcomes in the cumulative transfers of an intracytoplasmic sperm injection (ICSI) cycle along with blastocyst transfers in couples with normozoospermic males. Methods: The study included 252 couples who underwent their first ICSI cycles along with blastocyst transfer and whose male partner semen samples were normozoospermic according to the World Health Organization 2010 criteria. All the couples were classified into two groups based on the SDF: the low SDF group (SDF≤30%, n=162) and the high SDF group (SDF>30%, n=90). Clinical as well as laboratory outcomes were correlated between the two groups. Sperm DNA fragmentation was assessed on the post-wash semen samples by acridine orange test. The main outcome measures were the live birth rate and miscarriage rate. Results: A significant decrease in the live birth rates was observed in the high SDF group compared to the low SDF group in fresh embryo transfer cycles (P<0.05). However, no significant difference was observed in the clinical outcomes either in the frozen embryo transfer cycles or in the overall cumulative transfer cycles (P>0.05). No significant difference was observed in the laboratory outcomes between the two SDF groups. A remarkable decrease in sperm motility was observed in the high SDF group compared to the low SDF group (P<0.05). Conclusions: Sperm DNA fragmentation does not affect the clinical outcomes in the cumulative transfers of an ICSI cycle along with blastocyst transfers in couples with normozoospermic males.","PeriodicalId":8564,"journal":{"name":"Asian Pacific Journal of Reproduction","volume":"11 1","pages":"125 - 131"},"PeriodicalIF":0.0,"publicationDate":"2022-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42719235","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Antioxidant potential of pentoxifylline on spermatozoa of small ruminants 己酮茶碱对小反刍动物精子的抗氧化作用

Asian Pacific Journal of Reproduction Pub Date : 2022-05-01 DOI: 10.4103/2305-0500.346092

M. Alomar

{"title":"Antioxidant potential of pentoxifylline on spermatozoa of small ruminants","authors":"M. Alomar","doi":"10.4103/2305-0500.346092","DOIUrl":"https://doi.org/10.4103/2305-0500.346092","url":null,"abstract":"Objective: To investigate antioxidant potential of pentoxifylline on spermatozoa of small ruminants including rams and bucks. Methods: The levels of hydrogen peroxide (H2O2) production in ram and buck spermatozoa incubated with 0 (control), 4 and 8 mM of pentoxifylline were measured after 45-min incubation. Then, the motility parameters of ram and buck spermatozoa incubated with 0 (control), 1 mM of H2O2, 1 mM of H2O2 plus 4 mM of pentoxifylline, and 1 mM of H2O2 plus 8 mM of pentoxifylline were analysed. H2O2 was estimated using a fluorometric assay and spermatozoa motility characteristics were analyzed using computer aided sperm analyzer. Results: Pentoxifylline significantly decreased the levels of H2O2 produced from both ram and buck spermatozoa (P<0.05), and significant lower rates of H2O2 formation were noted when 8 mM of pentoxifylline was added (P<0.05). The values of all sperm motility parameters for the two species significantly decreased after incubation with H2O2 (P<0.05). In contrast, when the spermatozoa were incubated with both H2O2 and two concentrations of pentoxifylline, the motility values rose significantly compared to those incubated with H2O2 alone (P<0.05). For both ram and buck sperm samples, the rapid and static subpopulation motility parameters were the most affected categories by pentoxifylline addition compared to the medium and slow categories. Conclusions: Pentoxifylline possesses an antioxidant capacity proved by its ability of reducing H2O2 levels as well as by increasing motility values of stressed spermatozoa. Therefore, pentoxifylline could be recommended as antioxidant additive for spermatozoa of small ruminants under stress conditions.","PeriodicalId":8564,"journal":{"name":"Asian Pacific Journal of Reproduction","volume":"11 1","pages":"138 - 145"},"PeriodicalIF":0.0,"publicationDate":"2022-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42461235","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 2

Oxidative stress and female reproductive disorder: A review 氧化应激与女性生殖障碍:综述

Asian Pacific Journal of Reproduction Pub Date : 2022-05-01 DOI: 10.4103/2305-0500.346088

K. Manokaran, Pavithra Bhat, D. Nayak, Ravisankar Baskaran, Prabu Paramasivam, Shiek S. S. J. Ahmed, K. Priya, K. R. Ranganath Pai, Vignesh Balaji

引用次数: 5

Effect of cholesterol-loaded cyclodextrin enriched extenders on the quality of prefrozen and frozen buffalo semen 富含胆固醇的环糊精填充剂对预冻和冷冻水牛精液质量的影响

Asian Pacific Journal of Reproduction Pub Date : 2022-05-01 DOI: 10.4103/2305-0500.346093

A. Mostafa, M. El‐Belely, S. Ismail, R. El-Sheshtawy, M. Shahba

{"title":"Effect of cholesterol-loaded cyclodextrin enriched extenders on the quality of prefrozen and frozen buffalo semen","authors":"A. Mostafa, M. El‐Belely, S. Ismail, R. El-Sheshtawy, M. Shahba","doi":"10.4103/2305-0500.346093","DOIUrl":"https://doi.org/10.4103/2305-0500.346093","url":null,"abstract":"Objective: To investigate the effects of non-permeable cryoprotectant, cholesterol-loaded cyclodextrin, when added at different concentrations into cooled and frozen-thawed semen extended with Tris-citrate-fructose egg yolk glycerol and lecithin-based extenders. Methods: A total of 40 ejaculates from four buffalo bulls were collected using artificial vagina. Ejaculates were extended with one of Tris-citrate-fructose egg yolk glycerol and lecithin-based extenders which contained different concentrations [0 (control), 0.75, 1.50, 2.25 and 3.00 mg/mL] of cholesterol-loaded cyclodextrin. The extended semen samples were cooled to 5 °C and then frozen slowly to -196 °C in 0.25 mL ministraws before being stored in liquid nitrogen pending its evaluation. Sperm motility, live sperm, normal sperm morphology, sperm membrane integrity and acrosome morphology were measured. Results: Supplementation of cholesterol-loaded cyclodextrin improved progressive motility, viability, morphology and acrosome as well as plasma membrane integrities at 1.50-2.25 mg/mL depending upon types of used extenders and stages of pre- and post-freezing process (P<0.01). The best concentration was 1.50 mg/mL at pre-freeze stage and 2.25 mg/mL at post- freezing. However, greater concentration (3.00 mg/mL) of cholesterol-loaded cyclodextrin had a detrimental effect compared to the control group with the two evaluated extenders (P<0.01). Conclusions: Cholesterol-loaded cyclodextrin supplementation at 1.50-2.25 mg/mL concentration could improve pre-frozen and post-thawed buffalo sperm quality. The most suitable concentration is 1.50 mg/mL at pre-freeze stage and 2.25 mg/mL at post-freezing.","PeriodicalId":8564,"journal":{"name":"Asian Pacific Journal of Reproduction","volume":"11 1","pages":"146 - 152"},"PeriodicalIF":0.0,"publicationDate":"2022-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"45308923","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Placental pathologies and fetal outcome in pregnant women with COVID-19: A retrospective study COVID-19孕妇的胎盘病理和胎儿结局:一项回顾性研究

Asian Pacific Journal of Reproduction Pub Date : 2022-05-01 DOI: 10.4103/2305-0500.346091

S. Sarmadi, Ara Omranipour, E. Mirzaian, Roghayyeh Ahangari, Zahra Yazdi, A. Asgarian, Monireh Mirzaie

{"title":"Placental pathologies and fetal outcome in pregnant women with COVID-19: A retrospective study","authors":"S. Sarmadi, Ara Omranipour, E. Mirzaian, Roghayyeh Ahangari, Zahra Yazdi, A. Asgarian, Monireh Mirzaie","doi":"10.4103/2305-0500.346091","DOIUrl":"https://doi.org/10.4103/2305-0500.346091","url":null,"abstract":"Objective: To describe histopathologic findings in the placentas in women with coronavirus disease 2019 (COVID-19) during pregnancy. Methods: In a cross-sectional study, 38 pregnant women with COVID-19 and undergoing delivery between March 2020 and January 2022, were included. The patients had positive polymerase chain reaction (PCR) test for SARS-CoV-2 infection and the placentas after delivery were sent for histopathologic evaluation based on the Amsterdam Placental Workshop Group Consensus Statement and assessed by two pathologists. Results: Our results showed that maternal vascular malperfusion was the most common and was present in 17 cases (44.7%). These features included accelerated villous maturation (36.8%) distal villous hypoplasia (5.3%), placental infarction (5.3%) and intervillous fibrin deposition (10.5%). Other pathologic findings included focal calcification (10.5%), intravillous congestion and hemorrhage (10.5%), sub-chorionic hemorrhage (5.3%), acute villitis, chronic histiocytic intervillositis and delayed villous maturation each in one case (2.6%). Twelve out of 38 cases showed no significant pathologic changes. Fetal outcomes included neonatal intensive care unit admission rate of 13.2%, dyspnea 31.6%, newborn’s anosmia 7.9%, intrauterine fetal demise 2.6%, asphyxia 2.6% and neonate COVID infection 5.3%. Conclusions: Microvasculopathy, as a sign of maternal vascular malperfusion, is a common finding in placentas from SARS-CoV-2 positive pregnant women in the present study. Further studies with larger sample sizes and comparative studies between COVID-19 positive and negative, as well as information from patient follow-up are suggested.","PeriodicalId":8564,"journal":{"name":"Asian Pacific Journal of Reproduction","volume":"11 1","pages":"132 - 137"},"PeriodicalIF":0.0,"publicationDate":"2022-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44805965","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Protective effect of Scrophularia striata combined with trehalose and cysteine added to diluents on cryopreservd goat epididymal sperm 玄参联合海藻糖和半胱氨酸对冷冻保存山羊附睾精子的保护作用

Asian Pacific Journal of Reproduction Pub Date : 2022-03-01 DOI: 10.4103/2305-0500.341116

Zeinab Maleki, A. Farshad, J. Rostamzadeh

引用次数: 0

INRA82 extender enhances semen quality in ram under cooled and cryopreserved stages INRA82扩展剂可提高冷却和低温保存阶段公羊精液质量

Asian Pacific Journal of Reproduction Pub Date : 2022-03-01 DOI: 10.4103/2305-0500.341117

A. Fadl, E. Abdelnaby, H. El-Sherbiny

引用次数: 4