Asian Pacific journal of tropical medicine最新文献_第4页

Association between the Lung Immune Prognostic Index and mortality in patients with idiopathic inflammatory myopathy-associated interstitial lung disease 肺免疫预后指数与特发性炎症性肌病相关间质性肺病患者死亡率之间的关系

IF 3.1 4区医学

Asian Pacific journal of tropical medicine Pub Date : 2023-11-01 DOI: 10.4103/1995-7645.388386

Dan Luo, Zhihao Zhao, Caizheng Li, Wenjun Zhu, Wei Zhou, Lirong He, Huifeng Yan, Qiaoli Su

{"title":"Association between the Lung Immune Prognostic Index and mortality in patients with idiopathic inflammatory myopathy-associated interstitial lung disease","authors":"Dan Luo, Zhihao Zhao, Caizheng Li, Wenjun Zhu, Wei Zhou, Lirong He, Huifeng Yan, Qiaoli Su","doi":"10.4103/1995-7645.388386","DOIUrl":"https://doi.org/10.4103/1995-7645.388386","url":null,"abstract":"Objective: To explore the association between the Lung Immune Prognostic Index (LIPI) and 1-year all-cause mortality in patients with idiopathic inflammatory myopathy related interstitial lung disease (IIM-ILD). Methods: Patients who were diagnosed with IIM-ILD at West China Hospital, Sichuan University from January 2008 to December 2021 were retrospectively included and categorized into three groups based on LIPI. Univariable and multivariable Cox proportional hazards models were conducted to explore potential association between the LIPI and patients' mortality. Results: A total of 1116 patients were screened, and 830 were included in this study. The multivariable Cox analysis showed that, compared with patients with poor LIPI, the hazard ratio (HR) for all-cause 1-year mortality was 0.22 (95% CI 0.05-0.93, P=0.04) for patients in the good LIPI group (LDH<250 IU/L and dNLR<3). After excluding patients lost to follow-up within one year, a similar result was found for LIPI (HR 0.20, 95% CI 0.05-0.86; P=0.03). Conclusions: Good LIPI was independently associated with decreased risk of all-cause 1-year mortality in patients with IIM-ILD. This easy-to-obtain index might be served as a potential marker for assessing the prognosis of IIM-ILD.","PeriodicalId":8559,"journal":{"name":"Asian Pacific journal of tropical medicine","volume":null,"pages":null},"PeriodicalIF":3.1,"publicationDate":"2023-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139296107","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Disease burden, antimicrobial resistance and molecular characterization of invasive group B Streptococcus among non-pregnant adults in Malaysia: A protocol study 马来西亚非怀孕成年人中侵袭性 B 组链球菌的疾病负担、抗菌药耐药性和分子特征：协议研究

IF 3.1 4区医学

Asian Pacific journal of tropical medicine Pub Date : 2023-11-01 DOI: 10.4103/1995-7645.390165

AbdulRahman Muthanna, N. Baharin, Mohd Nasir Desa, N. Dzaraly, Mohammad Noor Azmai, Syafinaz Amin-Nordin

{"title":"Disease burden, antimicrobial resistance and molecular characterization of invasive group B Streptococcus among non-pregnant adults in Malaysia: A protocol study","authors":"AbdulRahman Muthanna, N. Baharin, Mohd Nasir Desa, N. Dzaraly, Mohammad Noor Azmai, Syafinaz Amin-Nordin","doi":"10.4103/1995-7645.390165","DOIUrl":"https://doi.org/10.4103/1995-7645.390165","url":null,"abstract":"Objective: To determine the prevalence of group B Streptococcus (GBS) isolated from non-pregnant adults from seven major hospitals in Peninsular Malaysia; the incidence, case-fatality ratio, antimicrobial susceptibility patterns, serotype, genotype and distribution of the GBS virulence and pili genes are also investigated. Methods: This multicentre, prospective, observational study is conducted in seven major tertiary hospitals in Malaysia among non-pregnant adults. Simultaneously, a retrospective study is conducted in the selected hospitals with similar approaches. GBS isolates are subjected to phenotyping, serotyping by multiplex PCR, antimicrobial susceptibility testing and PCR-detection of GBS virulence and pilus genes. Seven housekeeping genes are amplified and sequenced for multi-locus sequence typing. Discussion: Findings from the study may contribute to the management of clinical practice to diagnose and prevent GBS related diseases in a timely manner. Prudent use of antibiotics is encouraged by monitoring antimicrobial resistance.","PeriodicalId":8559,"journal":{"name":"Asian Pacific journal of tropical medicine","volume":null,"pages":null},"PeriodicalIF":3.1,"publicationDate":"2023-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139297851","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Myocarditis in scrub typhus-An uncommon presentation 恙虫病心肌炎--一种不常见的表现形式

IF 3.1 4区医学

Asian Pacific journal of tropical medicine Pub Date : 2023-11-01 DOI: 10.4103/1995-7645.390166

Rajendra Prasad Rao, L. Mohanty, Amit Jajodia, Santosh Sharma

引用次数: 0

Applications of nanomaterials in mosquito vector control: A review 纳米材料在蚊媒控制中的应用：综述

IF 3.1 4区医学

Asian Pacific journal of tropical medicine Pub Date : 2023-11-01 DOI: 10.4103/1995-7645.390164

Sahadiya Mandodan, Aneha Kunnikuruvan, Bhagyashree Bora, Hemaladkshmi Padmanaban, Abhisubesh Vijayakumar, Kakhuangailiu Gangmei, Manikandan Sivaprakasam, Jibi Lukose, Mathivanan Ashokkumar, Vijayalakshmi Krishnamoorthy, S. Poopathi

{"title":"Applications of nanomaterials in mosquito vector control: A review","authors":"Sahadiya Mandodan, Aneha Kunnikuruvan, Bhagyashree Bora, Hemaladkshmi Padmanaban, Abhisubesh Vijayakumar, Kakhuangailiu Gangmei, Manikandan Sivaprakasam, Jibi Lukose, Mathivanan Ashokkumar, Vijayalakshmi Krishnamoorthy, S. Poopathi","doi":"10.4103/1995-7645.390164","DOIUrl":"https://doi.org/10.4103/1995-7645.390164","url":null,"abstract":"The periodic outbreak of mosquito-borne diseases like dengue fever, zika fever, and yellow fever all over the world highlights the need for effective mosquito control methods targeting the biological system. Due to the lack of therapeutic measures, preventive treatments or vaccines against pathogens, insecticide resistance eventually lead the research focus towards novel technological applications in mosquito management. Nanomaterials with ovicidal, larvicidal, adulticidal, and repellent properties for controlling mosquito vectors are under research. A literature search was carried out for advancements in nanomaterials, insecticides, and mosquito control in PubMed/MEDLINE, Scopus, Google Scholar, ScienceDirect, and Web of Science. This paper aims to provide insights into various nanomaterials relevant to mosquito-borne diseases, in vivo and in vitro toxicity evaluation against mosquito species, mode of action, effect on non-target organisms, and ecological risks. Organic and inorganic materials that provide controlled release, target delivery, less dosage, prolonged efficacy, a reduction in the use of organic solvents and emulsifiers, and minimum pollution to the environment have already been explored. Indeed, further research on the ecological risk and economic feasibility of nanomaterials in mosquitocidal applications should be done prior to commercialization.","PeriodicalId":8559,"journal":{"name":"Asian Pacific journal of tropical medicine","volume":null,"pages":null},"PeriodicalIF":3.1,"publicationDate":"2023-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139298155","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Impact of H1N1, H7N9, ASFV, dengue virus and COVID-19 on pharmaceutical manufacturing firms' R&D investments and economic consequences: Evidence from China H1N1、H7N9、ASFV、登革热病毒和COVID-19对制药企业研发投资和经济后果的影响:来自中国的证据

4区医学

Asian Pacific journal of tropical medicine Pub Date : 2023-10-01 DOI: 10.4103/1995-7645.386256

Jie Liu, Wanqing Zheng, Zhen Liu, Xiujing Jiang

{"title":"Impact of H1N1, H7N9, ASFV, dengue virus and COVID-19 on pharmaceutical manufacturing firms' R&D investments and economic consequences: Evidence from China","authors":"Jie Liu, Wanqing Zheng, Zhen Liu, Xiujing Jiang","doi":"10.4103/1995-7645.386256","DOIUrl":"https://doi.org/10.4103/1995-7645.386256","url":null,"abstract":"Objective: To determine the impact of major disease epidemics on pharmaceutical manufacturing firms' Research & Development (R&D) investments and economic consequences. Methods: The sample consists of 1 582 firm-year observations from 2009 to 2022 in China, of which, 26.6% of pharmaceutical companies are involved in the diagnosis and treatment of prevalent diseases. Linear models using R&D investments, patent applications, operating performances and stock returns as dependent variables are constructed separately to examine the response of pharmaceutical companies to disease epidemics and the resulting economic consequences. Results: The prevalence of five major diseases led to a 17.5% increase in the amount of R&D investment and an 87.8% rise in the ratio of R&D investment to total assets by disease-related pharmaceutical companies, compared to unrelated pharmaceutical companies. Further evidence indicated that the patent applications for disease-related firms increased by 44.3% relative to unrelated firms after the epidemics. Though the impacts of the epidemics on firms' operating performances were insignificant in the short term, a major disease epidemic was associated with an increase in stock returns of 67.4% and 44.6%, respectively, as measured by the capital asset pricing model and Fama-French five-factor model. Additional analysis revealed that the impacts of the epidemics on R&D investments and patent applications were more pronounced for non-state-owned enterprises than state-owned enterprises. Conclusions: This study demonstrates that disease-related pharmaceutical firms respond to the disease epidemics through increasing R&D investment. More patent applications and higher market value are the main gains from the firms' increased investments in R&D following the epidemic, rather than the improvements of short-term operating performances.","PeriodicalId":8559,"journal":{"name":"Asian Pacific journal of tropical medicine","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"136152142","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

South Asian dairy smallholders: A scoping review of practices and zoonoses 南亚小奶农:对做法和人畜共患病的范围审查

4区医学

Asian Pacific journal of tropical medicine Pub Date : 2023-10-01 DOI: 10.4103/1995-7645.388029

Emily Schembri, Angus J D Campbell, Juan Pablo Villanueva-Cabezas

{"title":"South Asian dairy smallholders: A scoping review of practices and zoonoses","authors":"Emily Schembri, Angus J D Campbell, Juan Pablo Villanueva-Cabezas","doi":"10.4103/1995-7645.388029","DOIUrl":"https://doi.org/10.4103/1995-7645.388029","url":null,"abstract":"Objective: To identify and discuss on-farm management practices linked to bacterial zoonosis risk in smallholder dairy farmers in South Asia. Methods: This scoping review was conducted as per the PRISMA-ScR guidelines. Five hundred and two publications were retrieved from five online databases using a comprehensive search strategy. Studies were selected if they discussed a farm management practice which impacted human health within a South Asian country. Results: Twenty-two studies were included. Seven management practices relevant to farmers, livestock and their shared environment were identified including raw milk consumption, farm hygiene management, personal protective equipment uses, animal vaccination, cleaning udders, hand washing and disposal of afterbirth materials. Preventive practices were found to be utilized at lower frequencies compared to risk increasing practices. Awareness of bacterial zoonoses is particularly low within the region. Conclusions: Based on the results of this review, it was determined that improving farmer awareness of bacterial zoonotic diseases may favor several of the presented leverage points within the South Asian smallholder dairy system. Relying on formal school education to improve this awareness may not solve this problem, instead, more focus on accessible and affordable zoonoses education and farming programs is required.","PeriodicalId":8559,"journal":{"name":"Asian Pacific journal of tropical medicine","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135922516","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Aeromonas hydrophila infection in acute myeloid leukemia: A case report 急性髓系白血病并发嗜水气单胞菌感染1例

4区医学

Asian Pacific journal of tropical medicine Pub Date : 2023-10-01 DOI: 10.4103/1995-7645.388389

Rui He, Siqi Zhong, Jinghua Fan

{"title":"Aeromonas hydrophila infection in acute myeloid leukemia: A case report","authors":"Rui He, Siqi Zhong, Jinghua Fan","doi":"10.4103/1995-7645.388389","DOIUrl":"https://doi.org/10.4103/1995-7645.388389","url":null,"abstract":"Rationale: Aeromonas hydrophila , a bacterium commonly found in a variety of soils, aquatic habitats, and other natural environments, is known for causing infections and hemorrhagic diseases in both aquatic and terrestrial animals. Patients with leukemia, when infected by Aeromonas hydrophila following chemotherapy, face an increased risk of developing necrotizing fasciitis. Patient concerns: A 48-year-old male with a history of acute myeloid leukemia presented with swelling and pain in his right hand after being stabbed by a grass carp two days ago. The injury occurred on the fifth day after his last chemotherapy session when he was accidentally punctured in the right thumb and ring finger by a carp while fishing. Two days following the injury, the skin isurrounding the wound turned black immediately, while the rest of his hand was reddened, swollen, and bleeding. Diagnosis: Aeromonas hydrophila infection in the soft tissue of the right hand. Interventions: Intravenous antibiotics and local debridement. Outcomes: The patient experienced an alleviation of systemic poisoning symptoms, effective control of the local wound infection. Lessons: It is important for physicians to appreciate the potential for highly unusual and life-threatening infections in patients with acute myeloid leukemia. Early diagnosis and prompt treatment can prevent the development of necrotizing fasciitis and save patients' lives.","PeriodicalId":8559,"journal":{"name":"Asian Pacific journal of tropical medicine","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"136153044","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Malaria slide bank plays a crucial role in achieving and sustaining malaria elimination in India 疟疾幻灯片库在印度实现和维持消除疟疾方面发挥着关键作用

4区医学

Asian Pacific journal of tropical medicine Pub Date : 2023-10-01 DOI: 10.4103/1995-7645.388384

Shrikant Nema, Nitika Nitika, Anup R Anvikar, Praveen K Bharti

引用次数: 0

Risk estimation of chronic kidney disease in a leptospirosis endemic area: A case-control study from south Andaman Islands of India 钩端螺旋体病流行地区慢性肾脏疾病的风险评估:来自印度南安达曼群岛的病例对照研究

4区医学

Asian Pacific journal of tropical medicine Pub Date : 2023-10-01 DOI: 10.4103/1995-7645.388385

Ambreen Fatema, Manjunatha Ramu, Paluru Vijayachari

{"title":"Risk estimation of chronic kidney disease in a leptospirosis endemic area: A case-control study from south Andaman Islands of India","authors":"Ambreen Fatema, Manjunatha Ramu, Paluru Vijayachari","doi":"10.4103/1995-7645.388385","DOIUrl":"https://doi.org/10.4103/1995-7645.388385","url":null,"abstract":"Objective: To estimate the risk of chronic kidney disease in patients with leptospirosis. Methods: All reported (41 890) and later confirmed leptospirosis (1 990) cases from 2010-2020 were traced by universal sampling. 386 Laboratory-confirmed leptospirosis cases were enrolled and 413 age, gender, area, and occupation matched healthy persons were included as controls. Variables including socio-demographic characteristics, medical history, and health-related behaviours were compared between the two groups and association between these variables and reduced estimated glomerular filtration rate (eGFR) was analyzed with multiple linear regression. Results: The median of eGFR was 49.0 (27.0, 75.0) mL/min/1.73 m 2 in the cases and 96.0 (72.0, 121.0) mL/min/1.73 m 2 in the controls, showing significant differences ( P <0.001). Bivariate analysis showed that leptospirosis seropositivitiy, repeat leptospirosis infection, diabetes, male gender, working in field (sun exposure), COVID-19 infection and smoking had statistically significant association with reduced eGFR. Leptospirosis seropositivity had negative effects on eGFR. Multiple linear regression confirmed that leptospirosis seropositivity had negative effects on eGFR (unstandardised p coefficients= −30.86, 95% CI −49.7 to −11.9, P <0.001). Conclusions: Chronic kidney disease is a complex disease with multiple risk factors involved. Exposure to leptospirosis is one of the essential factors in accelerating its progression.","PeriodicalId":8559,"journal":{"name":"Asian Pacific journal of tropical medicine","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"136153876","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Public satisfaction with the quality of First Health Facility Services in Indonesia: Does sociodemographic matter? 公众对印尼第一卫生设施服务质量的满意度:社会人口因素重要吗?

4区医学

Asian Pacific journal of tropical medicine Pub Date : 2023-09-01 DOI: 10.4103/1995-7645.386257

Zainul Khaqiqi Nantabah, Rofingatul Mubasyiroh, Antonius Yudi Kristanto, Lely Indrawati, Astridya Paramita, Dwi Hapsari Tjandrarini, Agung Dwi Laksono

{"title":"Public satisfaction with the quality of First Health Facility Services in Indonesia: Does sociodemographic matter?","authors":"Zainul Khaqiqi Nantabah, Rofingatul Mubasyiroh, Antonius Yudi Kristanto, Lely Indrawati, Astridya Paramita, Dwi Hapsari Tjandrarini, Agung Dwi Laksono","doi":"10.4103/1995-7645.386257","DOIUrl":"https://doi.org/10.4103/1995-7645.386257","url":null,"abstract":"Objective: To investigate individual characteristics related to satisfaction with the quality of First Health Facility Services (FHFS) in Indonesia. Methods: This cross-sectional study analyzes national representation data. Meanwhile, the study involved 9846 representative respondents in 2019. Respondent's satisfaction with FHFS based on the five dimensions of service quality (SERVQUAL) is a dependent variable. Independent variables consist of sex, marital status, age, education, employment, insurance ownership, and economics. The study used multivariate logistic regression to explain the relationship between individual characteristics and FSHS quality. Results: 77.3% Respondents were satisfied with FHFS, with the highest order of satisfaction dimensions being assurance (59.4%), empathy (57.3%), reliability (53.6%), responsiveness (52.7%), and then tangibility (49.1%). Multivariate logistic analysis showed that divorce was 1.48 more likely than never-married to be satisfied (95% CI 1.17-1.87). Employees were 0.77 less likely than the unemployed to get satisfied (95% CI 0.70-0.86). Respondents with higher education was 0.82 less likely than those with primary education to be satisfied (95% CI 0.67-0.99). Meanwhile, respondents who had government-run insurance were 1.61 more likely than uninsured to be satisfied (95% CI 1.42-1.80). Moreover, the rich were 0.82 less likely than the poor to get satisfied (95% CI 0.73-0.92). Conclusions: Community satisfaction with FHFS is generally high, though some areas could be improved. Demographic factors are still strongly related to satisfaction ratings. The government can assess the quality of services in accordance with standards and disseminate information about service standards for primary facilities to all levels of society, ensuring that service satisfaction is rated as good by all groups.","PeriodicalId":8559,"journal":{"name":"Asian Pacific journal of tropical medicine","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135588427","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0