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P.29 Involvement of Cannabinoid Receptors in Regulation of MMPs, Cell Proliferation and Apoptosis in Vascular Smooth Muscle Cells P.29大麻素受体参与血管平滑肌细胞MMPs、细胞增殖和凋亡的调控
IF 0.6 4区 医学
Artery Research Pub Date : 2020-12-01 DOI: 10.2991/artres.k.201209.042
Bettina Greiner, M. Sommerfeld, U. Kintscher, K. Kappert, E. Kaschina
{"title":"P.29 Involvement of Cannabinoid Receptors in Regulation of MMPs, Cell Proliferation and Apoptosis in Vascular Smooth Muscle Cells","authors":"Bettina Greiner, M. Sommerfeld, U. Kintscher, K. Kappert, E. Kaschina","doi":"10.2991/artres.k.201209.042","DOIUrl":"https://doi.org/10.2991/artres.k.201209.042","url":null,"abstract":"1Charité Universitätsmedizin Berlin, corporate member of Freie Universität Berlin, Humboldt-Universität zu Berlin; and Berlin Institute of Health, Institute of Pharmacology, Center for Cardiovascular Research (CCR) 2DZHK (German Centre for Cardiovascular Research), partner site Berlin, Germany 3Berlin Institute of Health, Institute of Laboratory Medicine, Clinical Chemistry and Pathobiochemistry","PeriodicalId":8466,"journal":{"name":"Artery Research","volume":" ","pages":""},"PeriodicalIF":0.6,"publicationDate":"2020-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46820048","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
P.39 The Role of Advanced Glycation End Products in Vascular Ageing. Which Parameter is the Most Suitable as Biomarker? 晚期糖基化终产物在血管老化中的作用。哪个参数最适合作为生物标志物?
IF 0.6 4区 医学
Artery Research Pub Date : 2020-12-01 DOI: 10.2991/artres.k.201209.051
O. Mayer, J. Gelžinský, J. Seidlerová, J. Filipovský
{"title":"P.39 The Role of Advanced Glycation End Products in Vascular Ageing. Which Parameter is the Most Suitable as Biomarker?","authors":"O. Mayer, J. Gelžinský, J. Seidlerová, J. Filipovský","doi":"10.2991/artres.k.201209.051","DOIUrl":"https://doi.org/10.2991/artres.k.201209.051","url":null,"abstract":"","PeriodicalId":8466,"journal":{"name":"Artery Research","volume":" ","pages":""},"PeriodicalIF":0.6,"publicationDate":"2020-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41489146","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
P.47 Feasibility Evaluation of Imaging-Free Ultrasound Technology to Measure Diameters of Brachial and Radial Arteries for Assessment of Endothelial Function P.47无成像超声技术测量肱动脉和桡动脉直径评估内皮功能的可行性评估
IF 0.6 4区 医学
Artery Research Pub Date : 2020-12-01 DOI: 10.2991/artres.k.201209.059
Dinu S. Chandran, J. Joseph, Sakshi Sen, K. Raj, P. Nabeel, K. Deepak
{"title":"P.47 Feasibility Evaluation of Imaging-Free Ultrasound Technology to Measure Diameters of Brachial and Radial Arteries for Assessment of Endothelial Function","authors":"Dinu S. Chandran, J. Joseph, Sakshi Sen, K. Raj, P. Nabeel, K. Deepak","doi":"10.2991/artres.k.201209.059","DOIUrl":"https://doi.org/10.2991/artres.k.201209.059","url":null,"abstract":"Background: Ultrasonographic imaging to record changes in peripheral arterial diameter associated with Flow mediated dilatation or Low flow mediated constriction is routinely used to assess various facets of vascular endothelial function. Imaging poses many challenges including requirement of costly ultrasound machines, trained manpower to perform imaging and effortintensive steps to analyse the images subsequently using manual or automated methods. We tested the feasibility and validity of using an imaging-free technology to record resting arterial diameters of brachial and radial arteries.","PeriodicalId":8466,"journal":{"name":"Artery Research","volume":" ","pages":""},"PeriodicalIF":0.6,"publicationDate":"2020-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47679136","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
P.05 Development and Validation of a Novel Centroid Method for Estimating Effective Reflection Time P.05一种用于估计有效反射时间的新型质心方法的开发和验证
IF 0.6 4区 医学
Artery Research Pub Date : 2020-12-01 DOI: 10.2991/artres.k.201209.019
Avinash Kondiboyina, J. Smolich, M. Cheung, J. Mynard
{"title":"P.05 Development and Validation of a Novel Centroid Method for Estimating Effective Reflection Time","authors":"Avinash Kondiboyina, J. Smolich, M. Cheung, J. Mynard","doi":"10.2991/artres.k.201209.019","DOIUrl":"https://doi.org/10.2991/artres.k.201209.019","url":null,"abstract":"Background: The time at which reflected waves arrive at central arteries has an important influence on ventricular afterload. Current methods of estimating reflection time (RT), including zero-crossover [1], inflection-point [2], and foot methods [3], use only a single point on the pressure waveforms, and their accuracy is uncertain because no ground truth reflection time (GTRT) has been available. We here introduce a novel centroid method that accounts for the entire waveform and compare the accuracy of RT methods by comparison with a GTRT for the first time.","PeriodicalId":8466,"journal":{"name":"Artery Research","volume":" ","pages":""},"PeriodicalIF":0.6,"publicationDate":"2020-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47957295","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
P.35 TASK-1 Channels Play an Anticontractile Role in Rat Septal Coronary Artery Under Pharmacological Blockade of Endothelium P.35在内皮药理学阻断下，TASK-1通道在大鼠冠状动脉间隔中发挥抗收缩作用
IF 0.6 4区 医学
Artery Research Pub Date : 2020-12-01 DOI: 10.2991/artres.k.201209.048
B. S. V. Lazarenko, A. Shvetsova, D. Gaynullina, R. Schubert
{"title":"P.35 TASK-1 Channels Play an Anticontractile Role in Rat Septal Coronary Artery Under Pharmacological Blockade of Endothelium","authors":"B. S. V. Lazarenko, A. Shvetsova, D. Gaynullina, R. Schubert","doi":"10.2991/artres.k.201209.048","DOIUrl":"https://doi.org/10.2991/artres.k.201209.048","url":null,"abstract":"Purpose/Background/Objectives: TASK-1 (TWIK-related acid-sensitive potassium) channels conduct background K+ currents in smooth muscle cells of pulmonary arteries suppressing vasocontraction. However, the vasomotor role of TASK-1 channels in systemic arteries as well as their regulation by the endothelium are poorly understood. Therefore, we investigated the impact of TASK-1 channels on the regulation of arterial contraction in the presence or absence of the relaxing influence of the endothelium in the brain and the heart, important regions of the systemic circulation.","PeriodicalId":8466,"journal":{"name":"Artery Research","volume":" ","pages":""},"PeriodicalIF":0.6,"publicationDate":"2020-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48087214","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
P.38 Comparison of Arterial Hemodynamics in Early Vascular Aging (EVA), Average Vascular Aging (AVA) and Healthy Vascular Aging (HVA) P.38早期血管老化（EVA）、平均血管老化（AVA）和健康血管老化（HVA）中动脉血流动力学的比较
IF 0.6 4区 医学
Artery Research Pub Date : 2020-12-01 DOI: 10.2991/artres.k.201209.050
Chen-hua Lin, Cheng Hao-Min, Y. Ko, L. Peng, Liang‐Kung Chen, Chen-Huan Chen
{"title":"P.38 Comparison of Arterial Hemodynamics in Early Vascular Aging (EVA), Average Vascular Aging (AVA) and Healthy Vascular Aging (HVA)","authors":"Chen-hua Lin, Cheng Hao-Min, Y. Ko, L. Peng, Liang‐Kung Chen, Chen-Huan Chen","doi":"10.2991/artres.k.201209.050","DOIUrl":"https://doi.org/10.2991/artres.k.201209.050","url":null,"abstract":"Methods: Carotid and femoral pressure and central flow waveforms were noninvasively acquired in a total of 873 community residents (aged ≥50 years, mean age 66.9 years, 69.2% female). They were classified as EVA and HVA, according to the highest and lowest 10% of the cfPWV stratified by 5-year intervals. The remaining 80% were defined as average vascular aging (AVA). Macrovascular and microvascular functions were characterized by aortic input impedance, systemic vascular resistance and wave reflection indices.","PeriodicalId":8466,"journal":{"name":"Artery Research","volume":" ","pages":""},"PeriodicalIF":0.6,"publicationDate":"2020-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43172697","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
P.62 Assessment of Isoflavone and Ethanolic Extract of Inonotus Obliquus on Experimentally Induced Diabetes P.62斜枫异黄酮和乙醇提取物对实验性糖尿病的影响
IF 0.6 4区 医学
Artery Research Pub Date : 2020-12-01 DOI: 10.2991/artres.k.201209.071
K. Duru, C. Hildreth, A. Avolio, J. Phillips, M. Butlin
{"title":"P.62 Assessment of Isoflavone and Ethanolic Extract of Inonotus Obliquus on Experimentally Induced Diabetes","authors":"K. Duru, C. Hildreth, A. Avolio, J. Phillips, M. Butlin","doi":"10.2991/artres.k.201209.071","DOIUrl":"https://doi.org/10.2991/artres.k.201209.071","url":null,"abstract":"Methods: Diabetes was induced (streptozotocin 65 mg/kg, nicotinamide 110 mg/kg) in 9 male Wistar rats (12 weeks old). 9 additional rats were healthy controls. After 4 weeks animals were treated for 4 weeks with vehicle, isoflavone (200 mg/kg/day), or Inonotus obliquus (100 mg/kg/day). Blood pressure and metabolic caging were measured weekly. Glucose tolerance, renal function (serum creatinine, blood urea nitrogen (BUN) level, creatinine clearance rate) and heart, kidney and body weight were assessed at the end-point.","PeriodicalId":8466,"journal":{"name":"Artery Research","volume":" ","pages":""},"PeriodicalIF":0.6,"publicationDate":"2020-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44059963","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
P.33 Changes in Blood Pressure, Pulse Wave Velocity and Augmentation Index Induced by Postural Changes and Exercise P.33体位变化和运动引起的血压、脉搏波速度和增强指数的变化
IF 0.6 4区 医学
Artery Research Pub Date : 2020-12-01 DOI: 10.2991/artres.k.201209.046
E. Rodilla, J. Chordá, Andrea Gea, J. A. Costa
{"title":"P.33 Changes in Blood Pressure, Pulse Wave Velocity and Augmentation Index Induced by Postural Changes and Exercise","authors":"E. Rodilla, J. Chordá, Andrea Gea, J. A. Costa","doi":"10.2991/artres.k.201209.046","DOIUrl":"https://doi.org/10.2991/artres.k.201209.046","url":null,"abstract":"Methods: Cross-sectional, observational study in 63 voluntary healthy students. Age, height, weight, waist and smoking habits were assessed. We estimated peripheral and central BP, AIx and PWV (brachial oscillometry, AGEDIO, IEM®, Stollberg) after 5¢ in supine position (SUP), then after 30¢¢ in sitting (SIT) and again in sitting position after 25 squats in 30¢¢ (EXE). A validated questionnaire (Vital sign, https://www.seh-lelha.org/wp-content/uploads/2017/03/GuiaEjercicioRCV.pdf) was implemented to assess chronic physical condition (CPC).","PeriodicalId":8466,"journal":{"name":"Artery Research","volume":" ","pages":""},"PeriodicalIF":0.6,"publicationDate":"2020-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44114876","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
P.03 Local Pulse Wave Velocity Estimation using a Double Gaussian Propagation Model P.03使用双高斯传播模型的局部脉搏波速度估计
IF 0.6 4区 医学
Artery Research Pub Date : 2020-12-01 DOI: 10.2991/artres.k.201209.017
Fabian Beutel, C. Hoof, E. Hermeling
{"title":"P.03 Local Pulse Wave Velocity Estimation using a Double Gaussian Propagation Model","authors":"Fabian Beutel, C. Hoof, E. Hermeling","doi":"10.2991/artres.k.201209.017","DOIUrl":"https://doi.org/10.2991/artres.k.201209.017","url":null,"abstract":"","PeriodicalId":8466,"journal":{"name":"Artery Research","volume":"1 1","pages":""},"PeriodicalIF":0.6,"publicationDate":"2020-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41323738","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
P.37 An Assessment of Potential Sources of Error that May Arise in the Measurement of Carotid-Femoral Pulse Wave Velocity P.37颈动脉-股动脉脉搏波速度测量中可能出现的潜在误差源的评估
IF 0.6 4区 医学
Artery Research Pub Date : 2020-12-01 DOI: 10.2991/artres.k.201209.049
James Cox, Isabella Tan, A. Avolio, M. Butlin
{"title":"P.37 An Assessment of Potential Sources of Error that May Arise in the Measurement of Carotid-Femoral Pulse Wave Velocity","authors":"James Cox, Isabella Tan, A. Avolio, M. Butlin","doi":"10.2991/artres.k.201209.049","DOIUrl":"https://doi.org/10.2991/artres.k.201209.049","url":null,"abstract":"Objectives: Carotid-femoral pulse wave velocity (cfPWV) approximates aortic stiffness and is a predictor of cardiovascular events. Despite the literature highlighting the clinical relevance of cfPWV, there is minimal integration of this parameter in clinical assessments. An underlying reason may stem from potential measurement errors. This paper investigates the potential sources of error in the measurement of cfPWV.","PeriodicalId":8466,"journal":{"name":"Artery Research","volume":"60 ","pages":""},"PeriodicalIF":0.6,"publicationDate":"2020-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41277641","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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