Artery Research最新文献

{"title":"P.61 Impact of Kidney Transplantation on Arterial Reservoir-Wave Analysis","authors":"N. Côté, E. Philibert, M. Paré, R. Goupil, C. Fortier, M. Schultz, J. Sharman, M. Agharazii","doi":"10.2991/artres.k.201209.070","DOIUrl":"https://doi.org/10.2991/artres.k.201209.070","url":null,"abstract":"Purpose/Background/Objective: According to reservoir-wave approach (RWA) arterial pressure is the sum of a reservoir pressure (RP) accounting for dynamic storage and release of blood from arteries, and an excess pressure (XSP) analogous to flow. RP is the minimal left ventricular work required to generate aortic flow, while XSP corresponds to surplus cardiac workload. We have previously shown that kidney transplantation (KTx) improves aortic stiffness [1], however, by adding renal vessels to existing vascular network, KTx may increase cardiac output. Thus, we aimed to examine whether XSP increases after KTx.","PeriodicalId":8466,"journal":{"name":"Artery Research","volume":" ","pages":""},"PeriodicalIF":0.6,"publicationDate":"2020-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43138824","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"P.48 Ultrasound-Based Velocity and Acceleration of the Carotid Atheromatous Plaque in Asymptomatic Patients with Moderate and Severe Stenosis","authors":"K. Dalakleidi, S. Golemati, A. Gastounioti, C. Liapis, K. Nikita","doi":"10.2991/artres.k.201209.060","DOIUrl":"https://doi.org/10.2991/artres.k.201209.060","url":null,"abstract":"Methods: The dataset used consists of 38 sequences of B-mode images (videos) of carotid atheromatous plaque of asymptomatic patients. Among the examined carotid arteries, 27 had severe stenosis degrees (>70%) and 11 had moderate stenosis degrees (<70%). Plaque motion estimation was based on an adaptive block matching methodology which incorporates Kalman filtering update strategies. Plaque velocity and acceleration were calculated by differentiating displacement and velocity, respectively. The two-tailed t-test was used to assess statistically significant differences.","PeriodicalId":8466,"journal":{"name":"Artery Research","volume":" ","pages":""},"PeriodicalIF":0.6,"publicationDate":"2020-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47064377","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"P.50 Radial Artery Phenotyping in Fibromuscular Dysplasia Through Ultra-High Frequency Ultrasound: A Radiomic Approach","authors":"Federica Poli, R. Bruno, F. Faita, H. Khettab, M. Azizi, S. Vitali, M. Cosottini, D. Caramella, L. Ghiadoni, S. Taddei, P. Boutouyrie, A. Persu, X. Jeunemaître, A. Lorthioir","doi":"10.2991/artres.k.201209.062","DOIUrl":"https://doi.org/10.2991/artres.k.201209.062","url":null,"abstract":"Rationale and Aim: This study is aimed at identifying possible patterns of vascular wall disarray and remodeling in radial arteries of patients with fibromuscular dysplasia (FMD), by means of ultrahigh frequency ultrasound (UHFUS). Methods: UHFUS scans of the radial arteries and of 30 FMD patients and 30 healthy controls were obtained by VevoMD (70 MHz probe, FUJIFILM, VisualSonics, Toronto, Canada). 10 end-diastolic frames for each subject were analyzed. 74 radiomic features and 4 engineered parameters were extracted: intima-media thickness (IMT) and adventitia thickness (AT), an adjunctive acoustic interface for each layer (IMT and AT triple signal). The extracted parameters were used to train classification models, using Support Vector Machine Linear (SVM), K-Nearest Neighbors (KNN), Logistic Regression, Linear Discriminant Analysis (LDA). The models were then tested on an independent validation population (38 FMD patients and 28 healthy subjects). Results: IMT (185 ± 46 vs 168 ± 37, p =) and AT (104 ± 34 vs 96 ± 35, p = 0.004) were significantly higher in FMD than in controls. IMT and AT triple signal were also more frequent in FMD than in control images (p < for both). The most accurate classification models were LDA (sensitivity = 0.67, specificity = 0.76, accuracy = 0.71, AUC = 0.71) and Logistic Regression (sensitivity = 0.71, specificity = 0.72, accuracy = 0.71, AUC = 0.71). The models showed and accuracy of about 70% when tested on the validation population. Conclusions: Wall ultrastructure of radial arteries of FMD patients is extensively altered: IMT and AT are thickened and the first and/or second layer of the arterial wall is splitted, showing a triple signal feature. Radiomic descriptors combined with engineered parameters allow to distinguish between radial images from FMD patients and controls with a 70% accuracy. © 2020 Association for Research into Arterial Structure and Physiology. Publishing services by Atlantis Press International B.V. This is an open access article distributed under the CC BY-NC 4.0 license (http://creativecommons.org/licenses/by-nc/4.0/). Artery Research Vol. 26(S1); 2020, p. S73 DOI: https://doi.org/10.2991/artres.k.201209.062; ISSN 1872-9312; eISSN 1876-4401 https://www.atlantis-press.com/journals/artres *Corresponding author. Email: rosam.bruno@gmail.com","PeriodicalId":8466,"journal":{"name":"Artery Research","volume":" ","pages":""},"PeriodicalIF":0.6,"publicationDate":"2020-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48105573","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"P.44 Application of an Algorithm Developed for Measuring Gastrointestinal Motility to the Assessment of Arterial Mechanical Properties","authors":"Andrew Bard, S. Greenwald, Sreyash Sarkar","doi":"10.2991/artres.k.201209.056","DOIUrl":"https://doi.org/10.2991/artres.k.201209.056","url":null,"abstract":"Background: GIQuant (Motilent, London) is an algorithm for analysing cine-MRI, using the displacement fields generated by registration of indivisdual ciné frames. It produces a summary of how much movement occurs (“motility”) for anatomical locations within a reference image [1]. Although it is used clinically for quantifying gut motility [2], it can process any ciné-MRI. In this study, we explore the hypothesis that it can be used to examine the functionality of blood vessels.","PeriodicalId":8466,"journal":{"name":"Artery Research","volume":" ","pages":""},"PeriodicalIF":0.6,"publicationDate":"2020-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"45150494","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"P.29 Involvement of Cannabinoid Receptors in Regulation of MMPs, Cell Proliferation and Apoptosis in Vascular Smooth Muscle Cells","authors":"Bettina Greiner, M. Sommerfeld, U. Kintscher, K. Kappert, E. Kaschina","doi":"10.2991/artres.k.201209.042","DOIUrl":"https://doi.org/10.2991/artres.k.201209.042","url":null,"abstract":"1Charité Universitätsmedizin Berlin, corporate member of Freie Universität Berlin, Humboldt-Universität zu Berlin; and Berlin Institute of Health, Institute of Pharmacology, Center for Cardiovascular Research (CCR) 2DZHK (German Centre for Cardiovascular Research), partner site Berlin, Germany 3Berlin Institute of Health, Institute of Laboratory Medicine, Clinical Chemistry and Pathobiochemistry","PeriodicalId":8466,"journal":{"name":"Artery Research","volume":" ","pages":""},"PeriodicalIF":0.6,"publicationDate":"2020-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46820048","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"P.05 Development and Validation of a Novel Centroid Method for Estimating Effective Reflection Time","authors":"Avinash Kondiboyina, J. Smolich, M. Cheung, J. Mynard","doi":"10.2991/artres.k.201209.019","DOIUrl":"https://doi.org/10.2991/artres.k.201209.019","url":null,"abstract":"Background: The time at which reflected waves arrive at central arteries has an important influence on ventricular afterload. Current methods of estimating reflection time (RT), including zero-crossover [1], inflection-point [2], and foot methods [3], use only a single point on the pressure waveforms, and their accuracy is uncertain because no ground truth reflection time (GTRT) has been available. We here introduce a novel centroid method that accounts for the entire waveform and compare the accuracy of RT methods by comparison with a GTRT for the first time.","PeriodicalId":8466,"journal":{"name":"Artery Research","volume":" ","pages":""},"PeriodicalIF":0.6,"publicationDate":"2020-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47957295","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"P.35 TASK-1 Channels Play an Anticontractile Role in Rat Septal Coronary Artery Under Pharmacological Blockade of Endothelium","authors":"B. S. V. Lazarenko, A. Shvetsova, D. Gaynullina, R. Schubert","doi":"10.2991/artres.k.201209.048","DOIUrl":"https://doi.org/10.2991/artres.k.201209.048","url":null,"abstract":"Purpose/Background/Objectives: TASK-1 (TWIK-related acid-sensitive potassium) channels conduct background K+ currents in smooth muscle cells of pulmonary arteries suppressing vasocontraction. However, the vasomotor role of TASK-1 channels in systemic arteries as well as their regulation by the endothelium are poorly understood. Therefore, we investigated the impact of TASK-1 channels on the regulation of arterial contraction in the presence or absence of the relaxing influence of the endothelium in the brain and the heart, important regions of the systemic circulation.","PeriodicalId":8466,"journal":{"name":"Artery Research","volume":" ","pages":""},"PeriodicalIF":0.6,"publicationDate":"2020-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48087214","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"P.39 The Role of Advanced Glycation End Products in Vascular Ageing. Which Parameter is the Most Suitable as Biomarker?","authors":"O. Mayer, J. Gelžinský, J. Seidlerová, J. Filipovský","doi":"10.2991/artres.k.201209.051","DOIUrl":"https://doi.org/10.2991/artres.k.201209.051","url":null,"abstract":"","PeriodicalId":8466,"journal":{"name":"Artery Research","volume":" ","pages":""},"PeriodicalIF":0.6,"publicationDate":"2020-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41489146","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"P.47 Feasibility Evaluation of Imaging-Free Ultrasound Technology to Measure Diameters of Brachial and Radial Arteries for Assessment of Endothelial Function","authors":"Dinu S. Chandran, J. Joseph, Sakshi Sen, K. Raj, P. Nabeel, K. Deepak","doi":"10.2991/artres.k.201209.059","DOIUrl":"https://doi.org/10.2991/artres.k.201209.059","url":null,"abstract":"Background: Ultrasonographic imaging to record changes in peripheral arterial diameter associated with Flow mediated dilatation or Low flow mediated constriction is routinely used to assess various facets of vascular endothelial function. Imaging poses many challenges including requirement of costly ultrasound machines, trained manpower to perform imaging and effortintensive steps to analyse the images subsequently using manual or automated methods. We tested the feasibility and validity of using an imaging-free technology to record resting arterial diameters of brachial and radial arteries.","PeriodicalId":8466,"journal":{"name":"Artery Research","volume":" ","pages":""},"PeriodicalIF":0.6,"publicationDate":"2020-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47679136","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"P.38 Comparison of Arterial Hemodynamics in Early Vascular Aging (EVA), Average Vascular Aging (AVA) and Healthy Vascular Aging (HVA)","authors":"Chen-hua Lin, Cheng Hao-Min, Y. Ko, L. Peng, Liang‐Kung Chen, Chen-Huan Chen","doi":"10.2991/artres.k.201209.050","DOIUrl":"https://doi.org/10.2991/artres.k.201209.050","url":null,"abstract":"Methods: Carotid and femoral pressure and central flow waveforms were noninvasively acquired in a total of 873 community residents (aged ≥50 years, mean age 66.9 years, 69.2% female). They were classified as EVA and HVA, according to the highest and lowest 10% of the cfPWV stratified by 5-year intervals. The remaining 80% were defined as average vascular aging (AVA). Macrovascular and microvascular functions were characterized by aortic input impedance, systemic vascular resistance and wave reflection indices.","PeriodicalId":8466,"journal":{"name":"Artery Research","volume":" ","pages":""},"PeriodicalIF":0.6,"publicationDate":"2020-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43172697","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}