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Primer on Machine Learning in Electrophysiology. 电生理学中的机器学习入门。
IF 3
Arrhythmia & Electrophysiology Review Pub Date : 2023-01-01 DOI: 10.15420/aer.2022.43
Shane E Loeffler, Natalia Trayanova
{"title":"Primer on Machine Learning in Electrophysiology.","authors":"Shane E Loeffler,&nbsp;Natalia Trayanova","doi":"10.15420/aer.2022.43","DOIUrl":"https://doi.org/10.15420/aer.2022.43","url":null,"abstract":"<p><p>Artificial intelligence has become ubiquitous. Machine learning, a branch of artificial intelligence, leads the current technological revolution through its remarkable ability to learn and perform on data sets of varying types. Machine learning applications are expected to change contemporary medicine as they are brought into mainstream clinical practice. In the field of cardiac arrhythmia and electrophysiology, machine learning applications have enjoyed rapid growth and popularity. To facilitate clinical acceptance of these methodologies, it is important to promote general knowledge of machine learning in the wider community and continue to highlight the areas of successful application. The authors present a primer to provide an overview of common supervised (least squares, support vector machine, neural networks and random forest) and unsupervised (k-means and principal component analysis) machine learning models. The authors also provide explanations as to how and why the specific machine learning models have been used in arrhythmia and electrophysiology studies.</p>","PeriodicalId":8412,"journal":{"name":"Arrhythmia & Electrophysiology Review","volume":"12 ","pages":"e06"},"PeriodicalIF":3.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/19/2b/aer-12-e06.PMC10323871.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9812536","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Defibrillation Threshold Testing for Right-sided Device Implants: A Review to Inform Shared Decision-making, in Association with the British Heart Rhythm Society. 右侧装置植入的除颤阈值测试:与英国心律学会联合进行的一项综述，以告知共同决策。
IF 3
Arrhythmia & Electrophysiology Review Pub Date : 2023-01-01 DOI: 10.15420/aer.2022.38
Michael Tb Pope, John R Paisey, Paul R Roberts
{"title":"Defibrillation Threshold Testing for Right-sided Device Implants: A Review to Inform Shared Decision-making, in Association with the British Heart Rhythm Society.","authors":"Michael Tb Pope,&nbsp;John R Paisey,&nbsp;Paul R Roberts","doi":"10.15420/aer.2022.38","DOIUrl":"https://doi.org/10.15420/aer.2022.38","url":null,"abstract":"Prevention of sudden death using ICDs requires the reliable delivery of a high-energy shock to successfully terminate VF. Until more recently, the device implant procedure included conducting defibrillation threshold (DFT) testing involving VF induction and shock delivery to ensure efficacy. Large clinical trials, including SIMPLE and NORDIC ICD, have subsequently demonstrated that this is unnecessary, with a practice of omitting DFT testing having no impact on subsequent clinical outcomes. However, these studies specifically excluded patients requiring devices implanted on the right side, in whom the shock vector is significantly different and smaller studies suggest a higher DFT. In this review, the data regarding the use of DFT testing, focusing on right-sided implants, and the results of a survey of current UK practice are presented. In addition, a strategy of shared decision-making when it comes to deciding on the use of DFT testing during right-sided ICD implant procedures is proposed.","PeriodicalId":8412,"journal":{"name":"Arrhythmia & Electrophysiology Review","volume":"12 ","pages":"e10"},"PeriodicalIF":3.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/a3/0d/aer-12-e10.PMC10326664.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9815178","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
Atrial Transseptal Catheterisation: Challenging Scenarios and Techniques to Overcome Them. 房间隔置管:具有挑战性的场景和克服它们的技术。
IF 3
Arrhythmia & Electrophysiology Review Pub Date : 2023-01-01 DOI: 10.15420/aer.2022.25
Maiwand Mirwais, Pasquale Santangeli
{"title":"Atrial Transseptal Catheterisation: Challenging Scenarios and Techniques to Overcome Them.","authors":"Maiwand Mirwais,&nbsp;Pasquale Santangeli","doi":"10.15420/aer.2022.25","DOIUrl":"https://doi.org/10.15420/aer.2022.25","url":null,"abstract":"<p><p>Atrial transseptal catheterisation is a fundamental skill of any interventional electrophysiologist. In this review, various scenarios that pose unique challenges to atrial transseptal catheterisation are discussed. These scenarios include post-surgical or congenital malformations of the interatrial septum, presence of interatrial septal closure devices, absent or obstructed inferior vena cava and complex congenital heart disease after palliative surgery. Transseptal catheterisation in all of the above situations is feasible and can be performed safely with the aid of dedicated tools and specific techniques.</p>","PeriodicalId":8412,"journal":{"name":"Arrhythmia & Electrophysiology Review","volume":"12 ","pages":"e23"},"PeriodicalIF":3.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/ea/a6/aer-12-e23.PMC10466273.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10127552","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Ablation Lesion Assessment with MRI. MRI评估消融损伤
IF 2.6
Arrhythmia & Electrophysiology Review Pub Date : 2022-04-01 DOI: 10.15420/aer.2021.63
Lluís Mont, Ivo Roca-Luque, Till F Althoff
{"title":"Ablation Lesion Assessment with MRI.","authors":"Lluís Mont, Ivo Roca-Luque, Till F Althoff","doi":"10.15420/aer.2021.63","DOIUrl":"10.15420/aer.2021.63","url":null,"abstract":"<p><p>Late gadolinium enhancement (LGE) MRI is capable of detecting not only native cardiac fibrosis, but also ablation-induced scarring. Thus, it offers the unique opportunity to assess ablation lesions non-invasively. In the atrium, LGE-MRI has been shown to accurately detect and localise gaps in ablation lines. With a negative predictive value close to 100% it can reliably rule out pulmonary vein reconnection non-invasively and thus may avoid unnecessary invasive repeat procedures where a pulmonary vein isolation only approach is pursued. Even LGE-MRI-guided repeat pulmonary vein isolation has been demonstrated to be feasible as a standalone approach. LGE-MRI-based lesion assessment may also be of value to evaluate the efficacy of ventricular ablation. In this respect, the elimination of LGE-MRI-detected arrhythmogenic substrate may serve as a potential endpoint, but validation in clinical studies is lacking. Despite holding great promise, the widespread use of LGE-MRI is still limited by the absence of standardised protocols for image acquisition and post-processing. In particular, reproducibility across different centres is impeded by inconsistent thresholds and internal references to define fibrosis. Thus, uniform methodological and analytical standards are warranted to foster a broader implementation in clinical practice.</p>","PeriodicalId":8412,"journal":{"name":"Arrhythmia & Electrophysiology Review","volume":"11 1","pages":"e02"},"PeriodicalIF":2.6,"publicationDate":"2022-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9014705/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43229788","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Bridging the Gap Between Artificial Intelligence Research and Clinical Practice in Cardiovascular Science: What the Clinician Needs to Know 弥合人工智能研究与心血管科学临床实践之间的差距：临床医生需要知道的
IF 3
Arrhythmia & Electrophysiology Review Pub Date : 2022-04-01 DOI: 10.15420/aer.2022.07
Emily Shipley, Martha Joddrell, G. Lip, Yalin Zheng
{"title":"Bridging the Gap Between Artificial Intelligence Research and Clinical Practice in Cardiovascular Science: What the Clinician Needs to Know","authors":"Emily Shipley, Martha Joddrell, G. Lip, Yalin Zheng","doi":"10.15420/aer.2022.07","DOIUrl":"https://doi.org/10.15420/aer.2022.07","url":null,"abstract":"by the CHA 2 DS 2 VASc score. 5 More widespread use has the potential to improve patient-centred care by further individualising a patient’s level of risk, thus enabling the management of modifiable risk factors. An added benefit would be the ability to account for the dynamic nature of risk in certain cardiovascular outcomes. For example, ML and the use of mobile health data could enable stroke risk prediction to adapt to treatment changes over time and incident risk factors, in contrast with the static nature of current standard risk scores. 5 the explosion creation currently. methods of enabling improvement in performance of ML models. prediction of including AF and as supraventricular ectopic beat and to better use of of","PeriodicalId":8412,"journal":{"name":"Arrhythmia & Electrophysiology Review","volume":" ","pages":""},"PeriodicalIF":3.0,"publicationDate":"2022-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"45580004","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
Catecholaminergic Polymorphic Ventricular Tachycardia. 儿茶酚胺能多形性室性心动过速。
IF 3
Arrhythmia & Electrophysiology Review Pub Date : 2022-04-01 DOI: 10.15420/aer.2022.09
Mohamed Abbas, Chris Miles, Elijah Behr
{"title":"Catecholaminergic Polymorphic Ventricular Tachycardia.","authors":"Mohamed Abbas,&nbsp;Chris Miles,&nbsp;Elijah Behr","doi":"10.15420/aer.2022.09","DOIUrl":"https://doi.org/10.15420/aer.2022.09","url":null,"abstract":"<p><p>Catecholaminergic polymorphic ventricular tachycardia (CPVT) is an inherited arrhythmia syndrome characterised by adenergically mediated bidirectional and/or polymorphic ventricular tachycardia. CPVT is a significant cause of autopsy-negative sudden death in children and adolescents, although it can also affect adults. It is often caused by pathogenic variants in the cardiac ryanodine receptor gene as well as other rarer genes. Early identification and risk stratification is of major importance. β-blockers are the cornerstone of therapy. Sodium channel blockers, specifically flecainide, have an additive role. Left cardiac sympathetic denervation is playing an increasing role in suppression of arrhythmia and symptoms. Concerns have been raised, however, about the efficacy of implantable cardioverter defibrillator therapy and the risk of catecholamine driven proarrhythmic storms. In this review, we summarise the clinical characteristics, genetics, and diagnostic and therapeutic strategies for CPVT and describe recent advances and challenges.</p>","PeriodicalId":8412,"journal":{"name":"Arrhythmia & Electrophysiology Review","volume":"11 ","pages":"e20"},"PeriodicalIF":3.0,"publicationDate":"2022-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/5d/5d/aer-11-e20.PMC9820193.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10527379","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 4
What Cannot Be Missed: Important Publications on Electrophysiology in 2021. 不容错过:2021年关于电生理学的重要出版物。
IF 3
Arrhythmia & Electrophysiology Review Pub Date : 2022-04-01 DOI: 10.15420/aer.2022.04
Sanjiv M Narayan, Hugh Calkins, Andrew Grace, Gregory Yh Lip, Ken Ellenbogen, Pier D Lambiase, Demosthenes G Katritsis
{"title":"What Cannot Be Missed: Important Publications on Electrophysiology in 2021.","authors":"Sanjiv M Narayan,&nbsp;Hugh Calkins,&nbsp;Andrew Grace,&nbsp;Gregory Yh Lip,&nbsp;Ken Ellenbogen,&nbsp;Pier D Lambiase,&nbsp;Demosthenes G Katritsis","doi":"10.15420/aer.2022.04","DOIUrl":"https://doi.org/10.15420/aer.2022.04","url":null,"abstract":"Clinical Arrhythmias Atrial Fibrillation Lurie A, Wang J, Hinnegan KJ, et al. Prevalence of left atrial thrombus in anticoagulated patients with atrial fibrillation. J Am Coll Cardiol 2021;77:2875–86. https://doi.org/10.1016/j.jacc.2021.04.036; PMID: 34112315. • Left atrial thrombus prevalence is high in subgroups of anticoagulated patients with AF/atrial flutter, who may benefit from routine pre-procedural transoesophageal echocardiography before cardioversion or catheter ablation.","PeriodicalId":8412,"journal":{"name":"Arrhythmia & Electrophysiology Review","volume":"11 ","pages":"e01"},"PeriodicalIF":3.0,"publicationDate":"2022-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/87/ef/aer-11-e01.PMC9014699.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9173419","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Future Directions for Mapping Atrial Fibrillation. 心房颤动定位的未来方向。
IF 3
Arrhythmia & Electrophysiology Review Pub Date : 2022-04-01 DOI: 10.15420/aer.2021.52
Junaid Ab Zaman, Andrew A Grace, Sanjiv M Narayan
{"title":"Future Directions for Mapping Atrial Fibrillation.","authors":"Junaid Ab Zaman,&nbsp;Andrew A Grace,&nbsp;Sanjiv M Narayan","doi":"10.15420/aer.2021.52","DOIUrl":"https://doi.org/10.15420/aer.2021.52","url":null,"abstract":"Mapping for AF focuses on the identification of regions of interest that may guide management and – in particular – ablation therapy. Mapping may point to specific mechanisms associated with localised scar or fibrosis, or electrical features, such as localised repetitive, rotational or focal activation. In patients in whom AF is caused by disorganised waves with no spatial predilection, as proposed in the multiwavelet theory for AF, mapping would be of less benefit. The role of AF mapping is controversial at the current time in view of the debate over the underlying mechanisms. However, recent clinical expansions of mapping technologies confirm the importance of understanding the state of the art, including limitations of current approaches and potential areas of future development.","PeriodicalId":8412,"journal":{"name":"Arrhythmia & Electrophysiology Review","volume":"11 ","pages":"e08"},"PeriodicalIF":3.0,"publicationDate":"2022-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/c9/ff/aer-11-e08.PMC9194915.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10520102","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 2
Electro-energetics of Biventricular, Septal and Conduction System Pacing. 双室、间隔和传导系统起搏的电能量学。
IF 3
Arrhythmia & Electrophysiology Review Pub Date : 2021-12-01 DOI: 10.15420/aer.2021.30
Frits W Prinzen, Joost Lumens, Jürgen Duchenn, Kevin Vernooy
{"title":"Electro-energetics of Biventricular, Septal and Conduction System Pacing.","authors":"Frits W Prinzen,&nbsp;Joost Lumens,&nbsp;Jürgen Duchenn,&nbsp;Kevin Vernooy","doi":"10.15420/aer.2021.30","DOIUrl":"https://doi.org/10.15420/aer.2021.30","url":null,"abstract":"<p><p>Abnormal electrical activation of the ventricles creates abnormalities in cardiac mechanics. Local contraction patterns, as reflected by strain, are not only out of phase, but also show opposing length changes in early and late activated regions. Consequently, the efficiency of cardiac pump function (the amount of stroke work generated by a unit of oxygen consumed), is approximately 30% lower in dyssynchronous than in synchronous hearts. Maintaining good cardiac efficiency appears important for long-term outcomes. Biventricular, left ventricular septal, His bundle and left bundle branch pacing may minimise the amount of pacing-induced dyssynchrony and efficiency loss when compared to conventional right ventricular pacing. An extensive animal study indicates maintenance of mechanical synchrony and efficiency during left ventricular septal pacing and data from a few clinical studies support the idea that this is also the case for left bundle branch pacing and His bundle pacing. This review discusses electro-mechanics and mechano-energetics under the various paced conditions and provides suggestions for future research.</p>","PeriodicalId":8412,"journal":{"name":"Arrhythmia & Electrophysiology Review","volume":"10 4","pages":"250-257"},"PeriodicalIF":3.0,"publicationDate":"2021-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/6d/99/aer-10-250.PMC8785089.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9835426","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
Obesity and Atrial Fibrillation: Epidemiology, Pathogenesis and Effect of Weight Loss. 肥胖与房颤:流行病学、发病机制和减肥效果。
IF 3
Arrhythmia & Electrophysiology Review Pub Date : 2021-10-01 DOI: 10.15420/aer.2021.36
Ahmed M Al-Kaisey, Jonathan M Kalman
{"title":"Obesity and Atrial Fibrillation: Epidemiology, Pathogenesis and Effect of Weight Loss.","authors":"Ahmed M Al-Kaisey,&nbsp;Jonathan M Kalman","doi":"10.15420/aer.2021.36","DOIUrl":"https://doi.org/10.15420/aer.2021.36","url":null,"abstract":"<p><p>The obesity epidemic continues its relentless advance and is paralleled by an increase in the incidence of AF. Several epidemiological studies have highlighted obesity as an independent risk factor for the development of AF. This relationship is likely multifactorial through a number of interacting mechanisms. Weight loss through lifestyle changes or surgery has been associated with reverse remodelling of the atrial substrate and subsequent reduction in AF, making it an essential pillar in the management of AF in obese patients. In this review, the epidemiological data that support the obesity-AF relationship, the current insights into the underlying pathophysiological mechanism, the impact of weight loss on reverse remodelling and AF reduction, and the strategies to achieve weight loss in patients with AF are discussed.</p>","PeriodicalId":8412,"journal":{"name":"Arrhythmia & Electrophysiology Review","volume":"10 3","pages":"159-164"},"PeriodicalIF":3.0,"publicationDate":"2021-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/d4/24/aer-10-159.PMC8576485.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39876852","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 9
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