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Bridging the Gap Between Artificial Intelligence Research and Clinical Practice in Cardiovascular Science: What the Clinician Needs to Know 弥合人工智能研究与心血管科学临床实践之间的差距：临床医生需要知道的
IF 3
Arrhythmia & Electrophysiology Review Pub Date : 2022-04-01 DOI: 10.15420/aer.2022.07
Emily Shipley, Martha Joddrell, G. Lip, Yalin Zheng
{"title":"Bridging the Gap Between Artificial Intelligence Research and Clinical Practice in Cardiovascular Science: What the Clinician Needs to Know","authors":"Emily Shipley, Martha Joddrell, G. Lip, Yalin Zheng","doi":"10.15420/aer.2022.07","DOIUrl":"https://doi.org/10.15420/aer.2022.07","url":null,"abstract":"by the CHA 2 DS 2 VASc score. 5 More widespread use has the potential to improve patient-centred care by further individualising a patient’s level of risk, thus enabling the management of modifiable risk factors. An added benefit would be the ability to account for the dynamic nature of risk in certain cardiovascular outcomes. For example, ML and the use of mobile health data could enable stroke risk prediction to adapt to treatment changes over time and incident risk factors, in contrast with the static nature of current standard risk scores. 5 the explosion creation currently. methods of enabling improvement in performance of ML models. prediction of including AF and as supraventricular ectopic beat and to better use of of","PeriodicalId":8412,"journal":{"name":"Arrhythmia & Electrophysiology Review","volume":" ","pages":""},"PeriodicalIF":3.0,"publicationDate":"2022-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"45580004","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
Catecholaminergic Polymorphic Ventricular Tachycardia. 儿茶酚胺能多形性室性心动过速。
IF 3
Arrhythmia & Electrophysiology Review Pub Date : 2022-04-01 DOI: 10.15420/aer.2022.09
Mohamed Abbas, Chris Miles, Elijah Behr
{"title":"Catecholaminergic Polymorphic Ventricular Tachycardia.","authors":"Mohamed Abbas,&nbsp;Chris Miles,&nbsp;Elijah Behr","doi":"10.15420/aer.2022.09","DOIUrl":"https://doi.org/10.15420/aer.2022.09","url":null,"abstract":"<p><p>Catecholaminergic polymorphic ventricular tachycardia (CPVT) is an inherited arrhythmia syndrome characterised by adenergically mediated bidirectional and/or polymorphic ventricular tachycardia. CPVT is a significant cause of autopsy-negative sudden death in children and adolescents, although it can also affect adults. It is often caused by pathogenic variants in the cardiac ryanodine receptor gene as well as other rarer genes. Early identification and risk stratification is of major importance. β-blockers are the cornerstone of therapy. Sodium channel blockers, specifically flecainide, have an additive role. Left cardiac sympathetic denervation is playing an increasing role in suppression of arrhythmia and symptoms. Concerns have been raised, however, about the efficacy of implantable cardioverter defibrillator therapy and the risk of catecholamine driven proarrhythmic storms. In this review, we summarise the clinical characteristics, genetics, and diagnostic and therapeutic strategies for CPVT and describe recent advances and challenges.</p>","PeriodicalId":8412,"journal":{"name":"Arrhythmia & Electrophysiology Review","volume":"11 ","pages":"e20"},"PeriodicalIF":3.0,"publicationDate":"2022-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/5d/5d/aer-11-e20.PMC9820193.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10527379","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 4
What Cannot Be Missed: Important Publications on Electrophysiology in 2021. 不容错过:2021年关于电生理学的重要出版物。
IF 3
Arrhythmia & Electrophysiology Review Pub Date : 2022-04-01 DOI: 10.15420/aer.2022.04
Sanjiv M Narayan, Hugh Calkins, Andrew Grace, Gregory Yh Lip, Ken Ellenbogen, Pier D Lambiase, Demosthenes G Katritsis
{"title":"What Cannot Be Missed: Important Publications on Electrophysiology in 2021.","authors":"Sanjiv M Narayan,&nbsp;Hugh Calkins,&nbsp;Andrew Grace,&nbsp;Gregory Yh Lip,&nbsp;Ken Ellenbogen,&nbsp;Pier D Lambiase,&nbsp;Demosthenes G Katritsis","doi":"10.15420/aer.2022.04","DOIUrl":"https://doi.org/10.15420/aer.2022.04","url":null,"abstract":"Clinical Arrhythmias Atrial Fibrillation Lurie A, Wang J, Hinnegan KJ, et al. Prevalence of left atrial thrombus in anticoagulated patients with atrial fibrillation. J Am Coll Cardiol 2021;77:2875–86. https://doi.org/10.1016/j.jacc.2021.04.036; PMID: 34112315. • Left atrial thrombus prevalence is high in subgroups of anticoagulated patients with AF/atrial flutter, who may benefit from routine pre-procedural transoesophageal echocardiography before cardioversion or catheter ablation.","PeriodicalId":8412,"journal":{"name":"Arrhythmia & Electrophysiology Review","volume":"11 ","pages":"e01"},"PeriodicalIF":3.0,"publicationDate":"2022-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/87/ef/aer-11-e01.PMC9014699.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9173419","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Future Directions for Mapping Atrial Fibrillation. 心房颤动定位的未来方向。
IF 3
Arrhythmia & Electrophysiology Review Pub Date : 2022-04-01 DOI: 10.15420/aer.2021.52
Junaid Ab Zaman, Andrew A Grace, Sanjiv M Narayan
{"title":"Future Directions for Mapping Atrial Fibrillation.","authors":"Junaid Ab Zaman,&nbsp;Andrew A Grace,&nbsp;Sanjiv M Narayan","doi":"10.15420/aer.2021.52","DOIUrl":"https://doi.org/10.15420/aer.2021.52","url":null,"abstract":"Mapping for AF focuses on the identification of regions of interest that may guide management and – in particular – ablation therapy. Mapping may point to specific mechanisms associated with localised scar or fibrosis, or electrical features, such as localised repetitive, rotational or focal activation. In patients in whom AF is caused by disorganised waves with no spatial predilection, as proposed in the multiwavelet theory for AF, mapping would be of less benefit. The role of AF mapping is controversial at the current time in view of the debate over the underlying mechanisms. However, recent clinical expansions of mapping technologies confirm the importance of understanding the state of the art, including limitations of current approaches and potential areas of future development.","PeriodicalId":8412,"journal":{"name":"Arrhythmia & Electrophysiology Review","volume":"11 ","pages":"e08"},"PeriodicalIF":3.0,"publicationDate":"2022-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/c9/ff/aer-11-e08.PMC9194915.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10520102","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 2
Electro-energetics of Biventricular, Septal and Conduction System Pacing. 双室、间隔和传导系统起搏的电能量学。
IF 3
Arrhythmia & Electrophysiology Review Pub Date : 2021-12-01 DOI: 10.15420/aer.2021.30
Frits W Prinzen, Joost Lumens, Jürgen Duchenn, Kevin Vernooy
{"title":"Electro-energetics of Biventricular, Septal and Conduction System Pacing.","authors":"Frits W Prinzen,&nbsp;Joost Lumens,&nbsp;Jürgen Duchenn,&nbsp;Kevin Vernooy","doi":"10.15420/aer.2021.30","DOIUrl":"https://doi.org/10.15420/aer.2021.30","url":null,"abstract":"<p><p>Abnormal electrical activation of the ventricles creates abnormalities in cardiac mechanics. Local contraction patterns, as reflected by strain, are not only out of phase, but also show opposing length changes in early and late activated regions. Consequently, the efficiency of cardiac pump function (the amount of stroke work generated by a unit of oxygen consumed), is approximately 30% lower in dyssynchronous than in synchronous hearts. Maintaining good cardiac efficiency appears important for long-term outcomes. Biventricular, left ventricular septal, His bundle and left bundle branch pacing may minimise the amount of pacing-induced dyssynchrony and efficiency loss when compared to conventional right ventricular pacing. An extensive animal study indicates maintenance of mechanical synchrony and efficiency during left ventricular septal pacing and data from a few clinical studies support the idea that this is also the case for left bundle branch pacing and His bundle pacing. This review discusses electro-mechanics and mechano-energetics under the various paced conditions and provides suggestions for future research.</p>","PeriodicalId":8412,"journal":{"name":"Arrhythmia & Electrophysiology Review","volume":"10 4","pages":"250-257"},"PeriodicalIF":3.0,"publicationDate":"2021-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/6d/99/aer-10-250.PMC8785089.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9835426","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
Obesity and Atrial Fibrillation: Epidemiology, Pathogenesis and Effect of Weight Loss. 肥胖与房颤:流行病学、发病机制和减肥效果。
IF 3
Arrhythmia & Electrophysiology Review Pub Date : 2021-10-01 DOI: 10.15420/aer.2021.36
Ahmed M Al-Kaisey, Jonathan M Kalman
{"title":"Obesity and Atrial Fibrillation: Epidemiology, Pathogenesis and Effect of Weight Loss.","authors":"Ahmed M Al-Kaisey,&nbsp;Jonathan M Kalman","doi":"10.15420/aer.2021.36","DOIUrl":"https://doi.org/10.15420/aer.2021.36","url":null,"abstract":"<p><p>The obesity epidemic continues its relentless advance and is paralleled by an increase in the incidence of AF. Several epidemiological studies have highlighted obesity as an independent risk factor for the development of AF. This relationship is likely multifactorial through a number of interacting mechanisms. Weight loss through lifestyle changes or surgery has been associated with reverse remodelling of the atrial substrate and subsequent reduction in AF, making it an essential pillar in the management of AF in obese patients. In this review, the epidemiological data that support the obesity-AF relationship, the current insights into the underlying pathophysiological mechanism, the impact of weight loss on reverse remodelling and AF reduction, and the strategies to achieve weight loss in patients with AF are discussed.</p>","PeriodicalId":8412,"journal":{"name":"Arrhythmia & Electrophysiology Review","volume":"10 3","pages":"159-164"},"PeriodicalIF":3.0,"publicationDate":"2021-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/d4/24/aer-10-159.PMC8576485.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39876852","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 9
Simple is Complicated. 简单就是复杂
IF 3
Arrhythmia & Electrophysiology Review Pub Date : 2021-10-01 DOI: 10.15420/aer.2021.40
Demosthenes G Katritsis
{"title":"Simple is Complicated.","authors":"Demosthenes G Katritsis","doi":"10.15420/aer.2021.40","DOIUrl":"10.15420/aer.2021.40","url":null,"abstract":"","PeriodicalId":8412,"journal":{"name":"Arrhythmia & Electrophysiology Review","volume":"10 3","pages":"131"},"PeriodicalIF":3.0,"publicationDate":"2021-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/44/13/aer-10-131.PMC8576484.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39876847","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The Use of Electrocardiographic Imaging in Localising the Origin of Arrhythmias During Catheter Ablation of Ventricular Tachycardia. 心电成像在室性心动过速导管消融过程中心律失常根源定位中的应用。
IF 3
Arrhythmia & Electrophysiology Review Pub Date : 2021-10-01 DOI: 10.15420/aer.2021.27
Adam J Graham, Richard J Schilling
{"title":"The Use of Electrocardiographic Imaging in Localising the Origin of Arrhythmias During Catheter Ablation of Ventricular Tachycardia.","authors":"Adam J Graham,&nbsp;Richard J Schilling","doi":"10.15420/aer.2021.27","DOIUrl":"https://doi.org/10.15420/aer.2021.27","url":null,"abstract":"<p><p>Non-invasive electrocardiographic imaging (ECGI) is a novel clinical tool for mapping ventricular arrhythmia. Using multiple body surface electrodes to collect unipolar electrograms and conventional medical imaging of the heart, an epicardial shell can be created to display calculated electrograms. This calculation is achieved by solving the inverse problem and allows activation times to be calculated from a single beat. The technology was initially pioneered in the US using an experimental torso-shaped tank. Accuracy from studies in humans has varied. Early data was promising, with more recent work suggesting only moderate accuracy when reproducing cardiac activation. Despite these limitations, the system has been successfully used in pioneering work with non-invasive cardiac radioablation to treat ventricular arrhythmia. This suggests that the resolution may be sufficient for treatment of large target areas. Although untested in a well conducted clinical study it is likely that it would not be accurate enough to guide more discreet radiofrequency ablation.</p>","PeriodicalId":8412,"journal":{"name":"Arrhythmia & Electrophysiology Review","volume":"10 3","pages":"211-217"},"PeriodicalIF":3.0,"publicationDate":"2021-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/6c/6e/aer-10-211.PMC8576495.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39891187","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Sleep Apnoea and AF: Where Do We Stand? Practical Advice for Clinicians. 睡眠呼吸暂停和心房颤动:我们在哪里?给临床医生的实用建议
IF 3
Arrhythmia & Electrophysiology Review Pub Date : 2021-10-01 DOI: 10.15420/aer.2021.05
Suneet Mittal, David Golombeck, Jacqueline Pimienta
{"title":"Sleep Apnoea and AF: Where Do We Stand? Practical Advice for Clinicians.","authors":"Suneet Mittal,&nbsp;David Golombeck,&nbsp;Jacqueline Pimienta","doi":"10.15420/aer.2021.05","DOIUrl":"https://doi.org/10.15420/aer.2021.05","url":null,"abstract":"<p><p>AF is the most common sustained arrhythmia encountered in clinical practice. Among the largest contributing factors to the rapid increase in the incidence of AF are aging and obesity within the global population. Obstructive sleep apnoea (OSA) is a risk factor for AF that is clearly linked to obesity. Guidelines have advocated interrogation for clinical signs of OSA in all AF patients. The aim of this article is to provide practical advice for clinicians seeking to manage patients with AF and OSA. The authors discuss questionnaires to screen for OSA, various types of tests available for the diagnosis of OSA and data to assess the impact of treatment of OSA after various treatment options in AF patients. Finally, they outline the many areas that warrant further investigation in this patient population.</p>","PeriodicalId":8412,"journal":{"name":"Arrhythmia & Electrophysiology Review","volume":"10 3","pages":"140-146"},"PeriodicalIF":3.0,"publicationDate":"2021-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/ed/ec/aer-10-140.PMC8576511.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39876849","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 2
Hybrid Convergent Procedure for the Treatment of Persistent and Long-standing Persistent Atrial Fibrillation. 治疗持续性和长期持续性心房颤动的混合聚合程序。
IF 2.6
Arrhythmia & Electrophysiology Review Pub Date : 2021-10-01 DOI: 10.15420/aer.2021.24
David B DeLurgio, Jaswinder S Gill, Syed Ahsan, Riyaz A Kaba, Kristen M Plasseraud, Michael E Halkos
{"title":"Hybrid Convergent Procedure for the Treatment of Persistent and Long-standing Persistent Atrial Fibrillation.","authors":"David B DeLurgio, Jaswinder S Gill, Syed Ahsan, Riyaz A Kaba, Kristen M Plasseraud, Michael E Halkos","doi":"10.15420/aer.2021.24","DOIUrl":"10.15420/aer.2021.24","url":null,"abstract":"<p><p>Recent advances have been made in AF treatment, including the role of early rhythm control and landmark clinical trials using ablation therapy. However, some treatment gaps remain, including the creation of durable lesions outside the pulmonary veins and effective treatment of longstanding persistent AF. A novel epicardial-endocardial ablation approach - the hybrid convergent procedure - was developed to combine surgical and catheter ablation techniques into a collaborative, multidisciplinary approach to managing AF. In this review, the authors discuss recently published data on hybrid convergent ablation, including results of the CONVERGE clinical trial, in the context of current challenges to treatment of persistent and long-standing persistent AF. The review also aims to provide perspective on outstanding questions and future directions in this area.</p>","PeriodicalId":8412,"journal":{"name":"Arrhythmia & Electrophysiology Review","volume":"10 3","pages":"198-204"},"PeriodicalIF":2.6,"publicationDate":"2021-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/29/16/aer-10-198.PMC8576514.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39891185","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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