Archives of Environmental Contamination and Toxicology最新文献

{"title":"Radionuclides’ Dispersion from Coal-Fired Brick Kilns: Geo-Environmental Processes, Potential Risks and Management","authors":"Muhibul Munim,&nbsp;Rahat Khan,&nbsp;Md. Kawsaruzzaman,&nbsp;Kamrun Naher,&nbsp;Umma Tamim,&nbsp;Abubakr M. Idris,&nbsp;Md. Harunor Rashid Khan,&nbsp;Saad Aldawood,&nbsp;Abu Hekmot Mohammad Saadat,&nbsp;Md. Ahosan Habib","doi":"10.1007/s00244-024-01096-4","DOIUrl":"10.1007/s00244-024-01096-4","url":null,"abstract":"<div><p>In order to investigate the distributions and possible dispersion mechanism(s) of naturally occurring radioactive materials (NORMs: ²²⁶Ra, ²³²Th, and ⁴⁰K) from coal-based brick kilns, a systematic set (<i>n</i> = 60) of coal, ash, surface-soil, and subsurface soil samples were analyzed. High-quality analytical data of U, Th and K obtained from HPGe detector and TRIGA Mark-II research reactor-based neutron activation analysis were converted to the corresponding radioactivities. Average (<i>n</i> = 10) radioactivities of ²²⁶Ra, ²³²Th, and ⁴⁰ K in coal samples were 15.6, 16.7, and 145.5 Bq.kg⁻¹, respectively, where only ⁴⁰ K surpassed the corresponding global mean value. Average (<i>n</i> = 10) radioactivities of ²²⁶Ra, ²³²Th, and ⁴⁰ K in ash samples were 62.7, 88.5, and 521 Bq.kg⁻¹, respectively, where only ²²⁶Ra was within the established limit. In soil samples, average (<i>n</i> = 40) activities of ²²⁶Ra, ²³²Th, and ⁴⁰ K were 62.7, 95.1, and 641 Bq.kg⁻¹, respectively, which have surpassed the corresponding worldwide mean values. The observed differences in activity levels between soil samples collected near and far from the kilns, as well as between topsoil and subsoil samples, suggest the presence of distinct transport mechanisms for NORMs within the pedosphere. Dispersions of NORMs from the brick kilns to the ambient pedosphere are largely governed by aerodynamic convection and hydrodynamic leaching. These mechanisms are also influenced by geochemical mobility and relative solubility of NORMs, as well as factors such as rainfall patterns and wind-flow direction. Radiological indices invoke long-term carcinogenic-risks, whereas aerodynamic convection of finer particles (coal fly ash) from chimneys can cause significant health hazards to the nearby dwellers. Scientific processes as well as public awareness are essential to mitigate the risks.</p></div>","PeriodicalId":8377,"journal":{"name":"Archives of Environmental Contamination and Toxicology","volume":"87 4","pages":"386 - 408"},"PeriodicalIF":3.7,"publicationDate":"2024-10-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142543366","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"环境科学与生态学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Role of Organic Fertilizer in the Transfer of Lead to Vegetables Produced in Tropical Mountain Agroecosystems","authors":"Camila da Costa Barros de Souza,&nbsp;Erica Souto Abreu Lima,&nbsp;Andrés Calderín García,&nbsp;Nelson Moura Brasil do Amaral Sobrinho","doi":"10.1007/s00244-024-01094-6","DOIUrl":"10.1007/s00244-024-01094-6","url":null,"abstract":"<div><p>Understanding the relationship between the aerobic transformation of organic matter (OM) and the bioavailability of lead to plants may allow the safe application of organic fertilizers (OF) in agriculture. The present study aimed to elucidate the relationship of different OM structures with Pb, revealing the action of OF (poultry litter) on Pb dynamics, presenting the effects of OM transformations on bioavailability and transfer to vegetables produced in tropical mountain agroecosystems (TMA). The association of Pb with hydrophilic structures (CAlk–O and CAlk–di–O) during the aerobic transformation of poultry litter (PL) contributes to the increase in the water-soluble form of this metal (3.17–15.30%). The structural changes promoted by the transformation of OM, in addition to reducing the adsorption capacity of Pb in PL (Kd reduction from 1135.50 to 87.49), favor the formation of outer-sphere complexes. PL that have a more labile structure, i.e., those that are less humified, have greater affinity for Pb. The greater affinity of Pb for labile structures that are preserved in PL during OM transformations contributed to its increase and transport to edible plant parts. Considering the edible parts of vegetables grown in TMA and fertilized with fresh PL, 100% of broccoli, 91.78% of cabbage, 80.00% of tomato, 65.96% of parsley, 49.19% of lettuce, and 32.88% of cauliflower showed Pb contamination that exceeded the permitted level. Therefore, OF contributes to lead contamination of food produced in TMA, representing a risk to human health. Studies are needed to propose additional treatments for this residue before its use.</p></div>","PeriodicalId":8377,"journal":{"name":"Archives of Environmental Contamination and Toxicology","volume":"87 4","pages":"446 - 459"},"PeriodicalIF":3.7,"publicationDate":"2024-10-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142456857","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"环境科学与生态学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Examining Bald Eagle Contaminant Exposure and Reproductive Risk Above and Below Dams on Great Lakes Tributaries","authors":"Carly Jasmine Eakin,&nbsp;Lisa Williams,&nbsp;Jeremy Moore,&nbsp;Mandy Annis,&nbsp;David Best,&nbsp;Sarah Warner,&nbsp;William Bowerman,&nbsp;Latice Fuentes,&nbsp;Kendall Simon,&nbsp;Brandon Armstrong","doi":"10.1007/s00244-024-01090-w","DOIUrl":"10.1007/s00244-024-01090-w","url":null,"abstract":"<div><p>Removing lowermost dams can reestablish fish passage on Great Lakes tributaries. This can increase the transfer of contaminants from anadromous fish to piscivorous wildlife upstream; however, concentrations of bioaccumulative contaminants in Great Lakes fish have decreased over the last several decades. We analyzed concentrations of PCBs and the toxic equivalence (TEQs) calculated from PCBs, DDTs, other organochlorine pesticides, and PBDEs in the plasma of bald eagle nestlings above and below lowermost dams on five river systems in Michigan from 1999 to 2013. We examined relationships between contaminants and metrics of reproductive success from 1997 to 2018, including the effects of year and location relative to the lowermost dam. Σ₂₀PCB and <i>p,p’</i>-DDE were important in characterizing differences in contaminant mixtures above and below dams. Concentrations of contaminants were generally greater below dams than above. There were generally greater nest success and more nestlings per nest below dams, but nest location explained little variability (<i>R</i>² values = 0.03–0.15). Neither Σ₂₀PCB nor <i>p,p’</i>-DDE was a significant predictor of 5-year productivity means by river reach despite concentrations exceeding previously established effects thresholds for healthy bald eagle populations in the Great Lakes (≥ 1 nestling/nest). Our study indicates that dams may continue to reduce the upstream movement of contaminants to bald eagles, but at the measured concentrations, contaminants did not impair productivity and reproductive success as indicated by nestlings per nest. Additional information about population dynamics could clarify population-level effects of contaminants on bald eagles and to what degree these populations are self-sustaining throughout the Great Lakes.</p></div>","PeriodicalId":8377,"journal":{"name":"Archives of Environmental Contamination and Toxicology","volume":"87 4","pages":"353 - 374"},"PeriodicalIF":3.7,"publicationDate":"2024-10-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://link.springer.com/content/pdf/10.1007/s00244-024-01090-w.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142456856","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"环境科学与生态学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Decoupling Sources of Anthropogenic Influences on Sediments of the Visovac Lake (Krka National Park, Croatia) Using Multiparametric Approach","authors":"Iva Mikac,&nbsp;Niko Bačić,&nbsp;Petar Ujčić,&nbsp;Mavro Lučić,&nbsp;Neda Vdović,&nbsp;Maja Ivanić,&nbsp;Marijan Ahel,&nbsp;Nevenka Mikac","doi":"10.1007/s00244-024-01095-5","DOIUrl":"10.1007/s00244-024-01095-5","url":null,"abstract":"<div><p>Historical changes of sediment characteristics and levels of inorganic and organic contaminants were studied in dated sediment cores from the Visovac Lake, situated in the Krka National Park, Croatia, to identify the main sources of anthropogenic pressures on this highly protected system. Depth distributions of lithogenic elements showed a steady decrease of terrigenous inputs due to the reduction in agricultural activities in the area, which was particularly pronounced during the 1991–1995 war in Croatia. Vertical and longitudinal distributions of Cd and Zn indicated that they are predominately of anthropogenic origin. The historical profiles of these toxic metals coincide well with the recorded production of metal industry in the upper reach of the Krka River with a sharp decrease reflecting the interruption by the war and slow recovery afterwards. By contrast, the recovery of the tourist industry in Krka NP after the war was accompanied by increasing contamination by elements characteristic of boat and car traffic (Sn, Cu, Pb) as well as oil pollution. The contamination with polycyclic aromatic hydrocarbons and polychlorinated biphenyls was only moderate. Although levels of metallic and organic contamination can be considered relatively low, the observed shift from industrial to tourism-related sources indicated that touristic activities should also be regarded as a possible threat for this vulnerable karst aquatic ecosystem.</p></div>","PeriodicalId":8377,"journal":{"name":"Archives of Environmental Contamination and Toxicology","volume":"87 3","pages":"335 - 352"},"PeriodicalIF":3.7,"publicationDate":"2024-10-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142399144","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"环境科学与生态学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Microplastic's Contamination in the Hemolymph and Organs (Gills and Hepatopancreas) of Perna viridis","authors":"Muh Farhan,&nbsp;Khusnul Yaqin,&nbsp;Muhammad Iqbal Djawad","doi":"10.1007/s00244-024-01092-8","DOIUrl":"10.1007/s00244-024-01092-8","url":null,"abstract":"<div><p>The issue of microplastics (MPs) has emerged as a significant concern globally, with discussions surrounding the potential environmental impact of these tiny plastic particles becoming increasingly prevalent. This study aimed to identify the concentration and characteristics of MPs in hemolymph and organs (gills and hepatopancreas) of green mussels (<i>Perna viridis</i>) that are frequently consumed by people in Pangkajene Kepulauan, South Sulawesi Province, Indonesia. Green mussels were collected from two different sampling sites for comparison. Screening was carried out on dispensed hemolymph and dissected organs to identify the characteristics of MPs. Surface seawater sampling was added as information on MP's characteristics from the mussel habitat. Visual observation of MP's characteristics using a stereomicroscope in laminar flow is to prevent contamination. The identification of MP's polymer type is using FTIR-ATR. The results showed that hemolymph, hepatopancreas, gills, and surface water were concentrated with MPs. Small (2–3.9 cm) green mussels accumulated more MPs than medium (4–5.9 cm) and large (&gt; 6 cm). MPs characteristics of fiber shape, transparent color, and size 0.1–0.5 mm were dominant in all samples. A total of seven polymers of MPs were identified with polyethylene and polystyrene types most frequently found from all samples. Based on this study, green mussels are good for biomonitoring of MPs.</p></div>","PeriodicalId":8377,"journal":{"name":"Archives of Environmental Contamination and Toxicology","volume":"87 3","pages":"321 - 334"},"PeriodicalIF":3.7,"publicationDate":"2024-10-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142387499","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"环境科学与生态学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The Combined Effects of Temperature and pH to the Toxicity of the Water-Soluble Fraction of Gasoline (WSFG) to the Neotropical Yellow-Tail Tetra, Astyanax altiparanae","authors":"Giorgi Dal Pont,&nbsp;Antonio Ostrensky,&nbsp;Helen Sadauskas-Henrique,&nbsp;Gisela Geraldine Castilho-Westphal,&nbsp;Rafael Garrett Dolatto,&nbsp;Marco Tadeu Grassi,&nbsp;Luciana Rodrigues de Souza-Bastos","doi":"10.1007/s00244-024-01093-7","DOIUrl":"10.1007/s00244-024-01093-7","url":null,"abstract":"<div><p>Continental aquatic environments have undergone chemical pollution due to increased anthropogenic activities. Among those substances, petroleum hydrocarbons are a potential hazard for the aquatic animals. Additionally, alterations in the abiotic characteristics of the water, such as temperature and pH, can impose additional stress when those substances are present. We evaluate how alterations in water temperature and pH modified the acute (96 h) toxicity of the water-soluble fraction of gasoline (WSF_G) to <i>Astyanax altiparanae</i> through physiological analysis. We also investigated the physiological responses after the fish recovery from exposure (96 h) in clean water. Both isolated and combined exposures to WSF_G resulted in significant physiological changes. Alone, WSF_G altered energetic metabolism and haematopoietic functions, potentially due to metabolic hypoxia. When combined with changes in water temperature (30 °C) and pH (4.0), <i>A. altiparanae</i> activated additional physiological mechanisms to counterbalance osmoregulatory and acid–base imbalances, likely exacerbated by severe metabolic hypoxia. In both isolated and combined exposure scenarios, <i>A. altiparanae</i> maintained cellular hydration, suggesting a robust capacity to uphold homeostasis under environmental stress conditions. Following a recovery in clean water, energetic metabolism returned to control levels. Nevertheless, plasmatic Na⁺ and Cl⁻ levels and haematological parameters remained affected by WSF_G exposure. Our findings underscore the impact of interactions between WSF_G contaminants, temperature and pH, leading to additional biological damage in <i>A. altiparanae.</i></p></div>","PeriodicalId":8377,"journal":{"name":"Archives of Environmental Contamination and Toxicology","volume":"87 3","pages":"234 - 252"},"PeriodicalIF":3.7,"publicationDate":"2024-10-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142379992","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"环境科学与生态学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effect of Co-exposure to Additional Substances on the Bioconcentration of Per(poly)fluoroalkyl Substances: A Meta-Analysis Based on Hydroponic Experimental Evidence","authors":"Zi-wei Chen,&nbsp;Zu-lin Hua","doi":"10.1007/s00244-024-01087-5","DOIUrl":"10.1007/s00244-024-01087-5","url":null,"abstract":"<div><p>A consensus has yet to emerge regarding the bioconcentration responses of per(poly)fluoroalkyl substances under co-exposure with other additional substances in aqueous environments. This study employed a meta-analysis to systematically investigate the aforementioned issues on the basis of 1,085 published datasets of indoor hydroponic simulation experiments. A hierarchical meta-analysis model with an embedded variance covariance matrix was constructed to eliminate the non-independence and shared controls of the data. Overall, the co-exposure resulted in a notable reduction in PFAS bioaccumulation (cumulative effect size, CES =  − 0.4287, p &lt; 0.05) and bioconcentration factor (R² = 0.9507, k &lt; 1, b &lt; 0) in hydroponics. In particular, the inhibition of PFAS bioconcentration induced by dissolved organic matter (percentage form of the effect size, ES_P =  − 48.98%) was more pronounced than that induced by metal ions (ES_P =  − 35.54%), particulate matter (ES_P =  − 24.70%) and persistent organic pollutants (ES_P =  − 18.66%). A lower AS concentration and a lower concentration ratio of ASs to PFASs significantly promote PFAS bioaccumulation (p &lt; 0.05). The bioaccumulation of PFASs with long chains or high fluoride contents tended to be exacerbated in the presence of ASs. Furthermore, the effect on PFAS bioaccumulation was also significantly dependent on the duration of co-exposure (p &lt; 0.05). The findings of this study provide novel insights into the fate and bioconcentration of PFAS in aquatic environments under co-exposure conditions.</p></div>","PeriodicalId":8377,"journal":{"name":"Archives of Environmental Contamination and Toxicology","volume":"87 3","pages":"270 - 286"},"PeriodicalIF":3.7,"publicationDate":"2024-10-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142374995","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"环境科学与生态学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Multiple Biomarker Responses in Aegla castro Exposed to Copper: A Laboratory Approach","authors":"Jheimison Junior da Silva Rosa,&nbsp;Julia Andrade Cerqueira,&nbsp;Wagner Ezequiel Risso,&nbsp;Claudia Bueno dos Reis Martinez","doi":"10.1007/s00244-024-01091-9","DOIUrl":"10.1007/s00244-024-01091-9","url":null,"abstract":"<div><p>Although some biomarkers have already been determined in aeglids collected in the field, data from laboratory exposures are scarce. To our knowledge, no studies have investigated oxidative stress biomarkers in aeglids exposed to metals in the laboratory, or performed hemocyte counts and the comet assay using gill and hepatopancreas of aeglids. Thus, we investigated the effects of acute Cu exposure on intermolt males of <i>Aegla castro</i>, collected from a reference stream, acclimated for 6 days in the laboratory, and then exposed to 11 μg L⁻¹ of dissolved Cu (Cu 11) or only to water (CTR), for 24 h. Gill and hepatopancreas samples were used to determine Cu accumulation, DNA damage, and metallothionein content (MT), while hemolymph samples were used to determine Cu accumulation, DNA damage, and hemocyte counts. Muscle samples were used to determine Cu accumulation and acetylcholinesterase activity (AChE). Non-protein thiol content (NPSH), catalase (CAT), glutathione <i>S-</i>transferase activities (GST), lipoperoxidation (LPO), and protein carbonylation content (PCC) were measured only in the hepatopancreas. <i>Aegla castro</i> exposed to Cu accumulated this metal in gills and activated detoxification mechanisms, through increased MT content in the gill, and showed an immune response, evidenced by an increase in hyaline hemocytes. Therefore, gill and hemocytes appear to have a protective role in preventing the transport and bioavailability of Cu through the body. On the other hand, we observed a decrease in MT content in the hepatopancreas of crabs exposed to Cu, suggesting the excretion of MT in association with Cu bound to the sulfhydryl groups of this protein.</p><h3>Graphical Abstract</h3>\u0000<div><figure><div><div><picture><source><img></source></picture></div></div></figure></div></div>","PeriodicalId":8377,"journal":{"name":"Archives of Environmental Contamination and Toxicology","volume":"87 3","pages":"253 - 269"},"PeriodicalIF":3.7,"publicationDate":"2024-09-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142340148","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"环境科学与生态学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Dioxins, PFOS, and 20 other Persistent Organic Pollutants in Eggs of Nine Wild Bird Species from the Vaal River, South Africa","authors":"Velesia Lesch,&nbsp;Rialet Pieters,&nbsp;Hindrik Bouwman","doi":"10.1007/s00244-024-01088-4","DOIUrl":"10.1007/s00244-024-01088-4","url":null,"abstract":"<div><p>The Vaal River catchment drains the largest and most populated industrial and mining region in Southern Africa. Heron, ibis, cormorant, egrets, and darter eggs, representing three habitats and four feeding guilds, were collected at four locations in 2009/10 to identify hotspots and hazards associated with persistent organic pollutants (POPs). The POPs included 21 organochlorine pesticides, five polybrominated diphenyl ether (PBDE) classes, 18 polychlorinated biphenyls (PCBs including six non-dioxin-like PCBs; NDL-PCB), and 12 dioxin-like PCBs (DL-PCBs), 17 polychlorinated dibenzo-p-dioxins and dibenzo-p-furans (PCDD/Fs), and perfluorooctane sulfonate (PFOS). Aquatic predators had higher PFOS and PCDD/F concentrations, while PCBs dominated in terrestrial eggs. Organochlorine pesticides, PBDEs, and PCBs were strongly associated with eggs from the industrial regions, while PCDD/F concentrations were evenly distributed. PCDD/F and PCB toxic equivalency quotient concentrations were low with no adverse effects expected. PFOS peaked at Bloemhof Dam with a maximum of 2300 ng/g wm in an African Darter egg, indicating an unexpected PFOS hotspot, the source of which is unknown. Despite order of differences in compound class concentrations, there was no association with egg size. To the best of our knowledge, this is the only study that analysed all 2010 POPs in bird eggs on a large geographic scale. This study highlighted the importance of multi-species studies sampling from multiple locations to assess the risk that POPs pose to avian populations as hotspots and species at risk may be missed by studies looking at one or few species.</p></div>","PeriodicalId":8377,"journal":{"name":"Archives of Environmental Contamination and Toxicology","volume":"87 3","pages":"287 - 310"},"PeriodicalIF":3.7,"publicationDate":"2024-09-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://link.springer.com/content/pdf/10.1007/s00244-024-01088-4.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142279875","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"环境科学与生态学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Is Seven Days Enough? Comparing A 7-Day Exposure to the Classical 21-Day OECD TG 229 Fish Short-Term Reproduction Assay in Fathead Minnow","authors":"Julie Robitaille,&nbsp;Mélanie Desrosiers,&nbsp;Éloïse Veilleux,&nbsp;Marianne Métivier,&nbsp;Isabelle Guay,&nbsp;Molly Lefebvre-Raine,&nbsp;Valerie S. Langlois","doi":"10.1007/s00244-024-01089-3","DOIUrl":"10.1007/s00244-024-01089-3","url":null,"abstract":"<div><p>The OECD (Organisation for Economic Co-operation and Development) test guidelines (TG) 229—fish short-term reproduction assay (FSTRA) is one of the gold standard methods used to identify endocrine disrupting chemicals (EDCs). While informative, the FSTRA’s 5–6 week duration makes it difficult to use routinely. Prior studies have shown that EDCs’ impact on fecundity, vitellogenin (VTG) and steroid levels can be detected after less than 1 week of exposure suggesting the FSTRA could be shortened. This study compares both 7- and 21-day FSTRAs using fathead minnows (<i>Pimephales promelas</i>) for three known EDCs: 17α-ethinylestradiol (EE2; 40 ng/L), 17β-trenbolone (TRB; 50 µg/L), and propiconazole (PRP; 500 µg/L). All three compounds led to arrested fertility after 24 h of exposure, except for the 7-day EE2 treatment which still decreased reproduction. Moreover, independently of time of exposure, EE2 induced VTG production in males, and decreased estrogen levels in females and testosterone levels in males. In contrast, TRB-induced VTG production in males, while the levels were not different from controls in females even though testosterone levels increased, and masculinization was observed. Finally, PRP led to a decrease in VTG levels which was only significant during the 21-day exposure, and surprisingly, no effect on steroid levels were observed despite its known effects on steroidogenesis. For two of the three EDCs tested, both times of exposure led to similar outcomes supporting the shortening of the FSTRA to seven days. This proposed 7-day FSTRA could be used to screen EDCs in routine monitoring of environmental samples.</p></div>","PeriodicalId":8377,"journal":{"name":"Archives of Environmental Contamination and Toxicology","volume":"87 3","pages":"222 - 233"},"PeriodicalIF":3.7,"publicationDate":"2024-09-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142279876","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"环境科学与生态学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}