Archives of Women's Mental Health最新文献

{"title":"Menstrual distress in women with eating disorders: insights from the Menstrual Distress Questionnaire (MEDI-Q).","authors":"Eleonora Rossi, Emanuele Cassioli, Valentina Zofia Cordasco, Leda Caiati, Anita Rinaldo, Livio Tarchi, Cristiano Dani, Silvia Vannuccini, Felice Petraglia, Valdo Ricca, Giovanni Castellini","doi":"10.1007/s00737-024-01542-1","DOIUrl":"https://doi.org/10.1007/s00737-024-01542-1","url":null,"abstract":"<p><strong>Purpose: </strong>Despite the well-established association between Eating Disorders (EDs) and menstrual disorders, menstrual distress in women with EDs has not been thoroughly investigated. This study aimed to compare menstrual distress between patients with EDs and healthy controls (HCs), explore correlations between menstrual distress and ED psychopathology, and examine the differential impact of hormonal contraception on perceived menstruation-related distress in patients compared to HCs.</p><p><strong>Methods: </strong>A total of 132 patients with EDs and 105 HCs were recruited. Socio-demographic, anthropometric, and menstrual cycle data were collected. Self-administered questionnaires were used to evaluate premenstrual symptoms, ED psychopathology, and general psychopathology. The Menstrual Distress Questionnaire (MEDI-Q) was adopted for the assessment of menstrual distress.</p><p><strong>Results: </strong>Patients with EDs had higher scores in all menstrual distress subscales of MEDI-Q and higher premenstrual symptoms as compared to HCs, without differences between different ED diagnoses. Approximately 65% of distress was specific of the menstrual phase in both groups. Patients experienced particular symptoms as more distressful: muscle and osteoarticular pain, breast tenderness and widespread swelling sensation, headache, constipation, feeling of being impure, impulsiveness, anxiety, insomnia, and fatigue. Greater menstrual distress correlated with higher ED psychopathology. Hormonal contraceptive use predicted reduced menstrual distress in individuals with low ED psychopathology, but not in those with high ED psychopathology.</p><p><strong>Conclusion: </strong>These results highlighted the profound interplay between menstrual distress and psychopathology in women with EDs, with important clinical implications for both the therapeutic path of patients with EDs and the gynecological assessment of women experiencing menstrual distress.</p><p><strong>Article highlights: </strong>• Patients with eating disorders had higher MEDI-Q menstrual distress than controls. • 65% of menstrual distress was specific to the menstrual phase. • Patients found swelling, constipation and anxiety particularly distressful. • Greater menstrual distress correlated with higher eating disorder psychopathology. • Hormones did not reduce distress in presence of high eating psychopathology.</p>","PeriodicalId":8369,"journal":{"name":"Archives of Women's Mental Health","volume":" ","pages":""},"PeriodicalIF":3.2,"publicationDate":"2024-11-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142765799","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Neuroactive steroid levels are elevated in the follicular phase and predict premenstrual depression and anxiety symptom severity in women with menstrually related mood disorder.","authors":"Allison Kimball, Jenna Bourassa, Mark L Chicote, Anu V Gerweck, Laura E Dichtel, Karen K Miller","doi":"10.1007/s00737-024-01532-3","DOIUrl":"https://doi.org/10.1007/s00737-024-01532-3","url":null,"abstract":"<p><strong>Purpose: </strong>Menstrually related mood disorder (MRMD) is marked by severe affective symptoms in the late luteal phase of the menstrual cycle. We hypothesized that women with MRMD experience relative neuroactive steroid deficiency, specifically low allopregnanolone levels due to reduced conversion of progesterone, in association with the onset of affective symptoms in the late luteal phase.</p><p><strong>Methods: </strong>Nine subjects with MRMD and 14 healthy controls were studied. Daily Record of Severity of Problems was used to diagnose MRMD by DSM-5 criteria for premenstrual dysphoric disorder. Depression and anxiety symptom severity (16-Item Quick Inventory of Depressive Symptomatology Self Report, Generalized Anxiety Disorder 7-Item Scale) and levels of plasma neuroactive steroids by mass spectrometry were assessed at the mid-follicular, mid-luteal, and late luteal phases.</p><p><strong>Results: </strong>Depression severity was greater in women with MRMD than healthy controls in the late luteal phase only, as expected. In the mid-follicular phase, the mean allopregnanolone level and allopregnanolone/progesterone ratio were higher in women with MRMD than healthy controls. There were no differences between groups in luteal phase allopregnanolone levels. Higher follicular phase allopregnanolone sulfate and allopregnanolone levels were associated with greater depression severity in the mid-luteal and late luteal phases and greater anxiety severity in the late luteal phase.</p><p><strong>Conclusion: </strong>Levels of allopregnanolone, which have antidepressant effects, were higher in the mid-follicular phase in women with MRMD compared to healthy controls. In MRMD, increased conversion of progesterone to allopregnanolone in the mid-follicular phase may be a compensatory response to luteal phase depression and anxiety, or increased allopregnanolone levels could paradoxically trigger depression and anxiety.</p>","PeriodicalId":8369,"journal":{"name":"Archives of Women's Mental Health","volume":" ","pages":""},"PeriodicalIF":3.2,"publicationDate":"2024-11-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142725073","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Prevalence and social determinants of self-reported health status among reproductive age women in Nepal.","authors":"Ashfikur Rahman, Mortuja Mahamud Tohan, Amirul Islam, Bristi Rani Saha, Satyajit Kundu","doi":"10.1007/s00737-024-01528-z","DOIUrl":"10.1007/s00737-024-01528-z","url":null,"abstract":"<p><strong>Purpose: </strong>The self-reported health status (SRHS) is a subjective evaluation of an individual's health and has been connected to mortality and future health outcomes in numerous studies. However, the determinants of SRHS among women in Nepal remain largely unclear. In Nepal, traditional gender norms often result in women bearing greater responsibilities in terms of household chores, child-rearing, and taking care of elderly family members, all of which may potentially contribute to lower self-perceived health. Therefore, this study aims to identify the factors influencing SRHS among women in Nepal.</p><p><strong>Methods: </strong>The study utilized data from 7,442 women aged between 15 and 49 who participated in the Nepal Demographic and Health Survey (NDHS) 2022. Both univariate and multiple linear regression analyses were employed to ascertain the factors influencing self-rated health status (SRHS) among women in Nepal.</p><p><strong>Result: </strong>Women in the age groups 15-24 years (AOR: 5.14, 95% CI: 3.07-8.62) and 25-34 years (AOR: 2.71, 95% CI: 1.99-3.68) were more likely to report good health status compared to older age groups. Additionally, women who were never married (AOR: 4.89, 95% CI: 3.62-5.32) or currently married (AOR: 1.46, 95% CI: 1.11-2.20) and those from wealthy families (AOR: 1.54, 95% CI: 1.07-2.21), also had a higher likelihood of reporting good health status. Other factors associated with a higher probability of reporting good health included not having a history of terminated pregnancy (AOR: 1.48, 95% CI: 1.11-1.97), having no history of genital discharge (AOR: 1.75, 95% CI: 1.29-2.38), not visiting a health facility in the last 12 months (AOR: 2.03, 95% CI: 1.43-2.88), and having no genital ulcers in the previous 12 months (AOR: 2.02, 95% CI: 1.24-3.28). Conversely, women with mild to severe depression and anxiety were less likely to report good health status compared to those with no depression or anxiety.</p><p><strong>Conclusion: </strong>This study identified several social determinants of SRHS among Nepalese women. These socioeconomic determinants of health should be included in future research and health policy activities in Nepal and other comparable contexts.</p>","PeriodicalId":8369,"journal":{"name":"Archives of Women's Mental Health","volume":" ","pages":""},"PeriodicalIF":3.2,"publicationDate":"2024-11-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142666832","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Refugee mothers’ mental health in Denmark: possibilities and limits of home visiting programs","authors":"Maria Marti-Castaner,&nbsp;Vivian Rueskov Poulsen,&nbsp;Ezio Di Nucci,&nbsp;Sarah Fredsted Villadsen","doi":"10.1007/s00737-024-01529-y","DOIUrl":"10.1007/s00737-024-01529-y","url":null,"abstract":"<div><h3>Purpose</h3><p>To explore the experiences of refugee mothers and community health nurses participating in a nurse home visiting program in Denmark, focusing on the program’s effects on the psychosocial well-being of refugee mothers during the transition to motherhood.</p><h3>Methods</h3><p>The nurse home visiting program was an add-on the public care offered to all families, with extra training of the community health nurses and more time to engage with the families with immigrant and refugee backgrounds. Community health nurses (12) and participating women (9) participated in qualitative interviews between September and December 2020, following the program’s conclusion.</p><h3>Results</h3><p>Utilizing the Resource-Based Model of refugee adaptation as a theoretical framework, we identified four main themes: (i) negotiating parenting norms and gaining confidence through parenting resources; (ii) finding emotional support to cope with integration pressures; (iii) expanding social resources, (iv) building bridges with welfare state services. These themes captured the resources gained by mothers through the home visiting program, positively influencing their psychosocial well-being, while also acknowledging the impact of the socio-political context on community health nurses’ work and mothers’ daily lives.</p><h3>Conclusion</h3><p>Findings offer insights about the potential and limitations of tailored nurse home visiting programs for refugee families, emphasizing the positive impact on mental health. However, challenges such as assimilation pressures, unwelcoming immigration policies, and discrimination may hinder program effectiveness.</p></div>","PeriodicalId":8369,"journal":{"name":"Archives of Women's Mental Health","volume":"28 2","pages":"245 - 255"},"PeriodicalIF":3.2,"publicationDate":"2024-11-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://link.springer.com/content/pdf/10.1007/s00737-024-01529-y.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142666834","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"New perinatal mental health conditions diagnosed during COVID-19: a population-based, retrospective cohort study of birthing people in Ontario.","authors":"Rebecca H Correia, Devon Greyson, David Kirkwood, Elizabeth K Darling, Manisha Pahwa, Hamideh Bayrampour, Aaron Jones, Cassandra Kuyvenhoven, Jessica Liauw, Meredith Vanstone","doi":"10.1007/s00737-024-01534-1","DOIUrl":"10.1007/s00737-024-01534-1","url":null,"abstract":"<p><strong>Purpose: </strong>We aimed to determine the incidence of mental health diagnoses and associated health and social risk factors among perinatal people in three different COVID-19 phases.</p><p><strong>Methods: </strong>We conducted a population-based, retrospective cohort study using linked administrative datasets. We included persons with live, in-hospital births in Ontario, Canada from January 1 to March 31 in 2019, 2021, or 2022 (three phases relative to COVID-19 with different public health policy measures). We excluded people with prior mental health diagnoses. We used diagnostic codes to identify new onset of depression, anxiety, or adjustment disorder in the antenatal and postpartum period. We developed multivariable, modified Poisson models to examine associations between sociodemographic and clinical factors and new mental health diagnoses in each phase.</p><p><strong>Results: </strong>There were 72,242 people in our cohort. Antenatal mental health diagnoses were significantly higher in 2021 (aRR = 1.32; CI = 1.20-1.46) and 2022 (aRR = 1.22; CI = 1.11-1.35) versus 2019. Postpartum diagnoses were significantly greater in 2021 (aRR = 1.16; CI = 1.08-1.25) versus 2019. Antenatal diagnoses were associated with birth year, previous stillbirth, pre-existing hypertension, multiparity, residential instability, and ethnocultural diversity. Postpartum diagnoses were associated with birth year, maternal age, multiparity, care provider profession, assisted reproductive technology, birthing mode, pre-existing hypertension, intensive care admission, hospital readmission, residential instability, and ethnocultural diversity. Family physicians increasingly made mental health diagnoses in 2021 and 2022.</p><p><strong>Conclusion: </strong>Increased incidence of perinatal mental health diagnoses during COVID-19 suggests complex dynamics involving pandemic and health and social risk factors.</p><p><strong>Registration: </strong>This study was registered with Clinicaltrials.gov (NCT05663762) on December 21, 2022.</p>","PeriodicalId":8369,"journal":{"name":"Archives of Women's Mental Health","volume":" ","pages":""},"PeriodicalIF":3.2,"publicationDate":"2024-11-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142666814","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Impact of work hours on sleep quality: a non-linear and gendered disparity.","authors":"Tinh Doan, Liana Leach, Lyndall Strazdins","doi":"10.1007/s00737-024-01535-0","DOIUrl":"https://doi.org/10.1007/s00737-024-01535-0","url":null,"abstract":"<p><strong>Purpose: </strong>Quality sleep is vital for good health. Although it is known that workhours affect sleep quality, it is not known at what point workhours begin to compromise sleep. Few studies consider workhours in the 'other job' (domestic and care work) or address reverse causality between sleep quality and how long people work. This study aimed to estimate the point at which weekly workhours harm sleep, among employed Australians aged 25-64.</p><p><strong>Methods: </strong>Using Australian data (19,453 observations from 9,826 adults assessed 2013, 2017, and 2021), a maximum likelihood instrumental variable approach modelled the influence of domestic and care hours on workhours and then the effect of workhours on sleep. We tested for a non-linear pattern and a potential tipping point or limit at which sleep quality declines. Sleep quality scores were constructed from sleep duration (hours), quality rating, medications, and problems with onset.</p><p><strong>Results: </strong>We estimated a population tipping point of 42 workhours per week, beyond which sleep quality deteriorated. Notably, women demonstrated a lower tipping point (36 h) beyond which their sleep quality deteriorated compared to men (47 h), likely linked to their greater care and domestic workhours in the home.</p><p><strong>Conclusions: </strong>Our methods allowed us to specify the point at which weekly workhours were optimal for sleep quality and the point beyond which they become harmful. By considering unequal hours worked in care and domestic work, we were able to identify distinct gender differences in this relationship.</p>","PeriodicalId":8369,"journal":{"name":"Archives of Women's Mental Health","volume":" ","pages":""},"PeriodicalIF":3.2,"publicationDate":"2024-11-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142646205","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The prevalence of traumatic exposure in women with premenstrual dysphoric disorder (PMDD): a systematic review.","authors":"Jasleen Kaur Grewal, Eveline Mu, Qi Li, Elizabeth H X Thomas, Jayashri Kulkarni, Leo Chen","doi":"10.1007/s00737-024-01536-z","DOIUrl":"https://doi.org/10.1007/s00737-024-01536-z","url":null,"abstract":"<p><strong>Background and purpose: </strong>Premenstrual dysphoric disorder (PMDD) is a debilitating illness that affects 3-8% of women worldwide. There are multiple factors underlying the aetiology of PMDD, ranging from neuroendocrine changes to psychosocial factors such as exposure to trauma. This systematic review aims to assess the prevalence of traumatic exposure in women with PMDD.</p><p><strong>Methods: </strong>A literature search of MEDLINE, EMBASE and PsycInfo was conducted following PRISMA guidelines. Of the 369 studies identified for abstract and full-text screening, 27 were included for review and 16 studies for the quantitative calculation of average prevalence and 95% confidence intervals. Data extracted included study details, sampling details, demographic details, type of traumatic exposure reported, diagnostic tools used, the prevalence of PMDD (total) and the prevalence of self-reported traumatic exposure in PMDD patients.</p><p><strong>Results: </strong>The reported prevalence of traumatic exposure in PMDD ranged from 18.03 to 90.5%. Using a random effects model, the pooled prevalence was 61% (95%CI, 46-74%). The level of heterogeneity (I²) was 95%, showing considerable variability in the data. Amongst only those studies with a control group, it was shown that those with PMDD are 1.99 times more likely to have a history of traumatic exposure than those without PMDD.</p><p><strong>Conclusion: </strong>Our findings suggest that a history of traumatic exposure is highly represented in women living with PMDD. Trauma exposure may be a risk factor for PMDD and could inform this condition's aetiology. A trauma-informed approach should be considered when assessing and managing women presenting with PMDD.</p>","PeriodicalId":8369,"journal":{"name":"Archives of Women's Mental Health","volume":" ","pages":""},"PeriodicalIF":3.2,"publicationDate":"2024-11-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142638308","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Associations between lifetime reproductive events among postmenopausal women with bipolar disorder","authors":"Katherine Gordon-Smith,&nbsp;Amy Perry,&nbsp;Arianna Di Florio,&nbsp;Nicholas Craddock,&nbsp;Ian Jones,&nbsp;Lisa Jones","doi":"10.1007/s00737-024-01533-2","DOIUrl":"10.1007/s00737-024-01533-2","url":null,"abstract":"<div><h3>Purpose</h3><p>The premenstrual phase of the menstrual cycle, childbirth and perimenopause often coincide with a worsening of mood symptoms in women with bipolar disorder (BD). To date, findings from the limited number of studies investigating associations between these events among women with BD have been inconsistent. This study aimed to investigate associations between episodes in relation to the perimenopause and (i) premenstrual symptoms and (ii) postpartum mood episodes in a large sample of postmenopausal women with BD.</p><h3>Methods</h3><p>Among 567 postmenopausal women with BD, recruited as part of the UK Bipolar Disorder Research Network, relationships between reproductive event-associated mood symptoms/episodes were examined. Multivariate binary analyses were carried out to identify if history of premenstrual symptoms and/or postpartum episodes predicted the occurrence of mood episodes in relation to the perimenopause, controlling for potential confounders including number of mood episodes per illness year.</p><h3>Results</h3><p>History of premenstrual symptoms was associated with experiencing any type of mood episode, and depression specifically, during the perimenopause (OR 6.189, <i>p</i> &lt; 0.001 and OR 2.709, <i>p</i> = 0.019 respectively). History of postpartum depression within 6 weeks of delivery was associated with depressive episodes during the perimenopause (OR 2.635, <i>p</i> = 0.027). Postpartum mania was not a significant predictor.</p><h3>Conclusions</h3><p>Our findings suggest that women with BD with a history of premenstrual symptoms and postpartum depression are potentially at increased risk of experiencing episodes of depression in relation to the perimenopause. There are clinical and self-management implications in identifying a subgroup of women with BD who may be particularly vulnerable to episodes of mood disturbance during reproductive events.</p></div>","PeriodicalId":8369,"journal":{"name":"Archives of Women's Mental Health","volume":"28 3","pages":"573 - 581"},"PeriodicalIF":3.2,"publicationDate":"2024-11-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://link.springer.com/content/pdf/10.1007/s00737-024-01533-2.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142613747","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Attention control in the peripartum period: a longitudinal study","authors":"Tamar Bakun Emesh,&nbsp;Nachshon Meiran,&nbsp;Dar Ran-Peled,&nbsp;Hamutal Ben-Zion,&nbsp;Avel Horwitz,&nbsp;Omer Finkelstein,&nbsp;Liat Tikotzky","doi":"10.1007/s00737-024-01530-5","DOIUrl":"10.1007/s00737-024-01530-5","url":null,"abstract":"<div><h3>Purpose</h3><p>Given research inconsistency, this study aimed to assess whether attention control changes from pregnancy to postpartum, focusing on the moderating role of maternal objective and subjective sleep. Our second objective was to evaluate attention control’s role in predicting psychological outcomes in peripartum women.</p><h3>Method</h3><p>A cohort of 224 pregnant women completed the Antisaccade task, a measure of attention control, during the third trimester and again four months post-delivery. Objective and subjective sleep were measured using actigraphy and sleep diaries. Participants also completed questionnaires assessing depression, anxiety, emotion regulation, and maternal perceptions of the mother-infant relationship.</p><h3>Results</h3><p>Attention control improved significantly from late pregnancy to postpartum (β = 0.91, <i>p</i> &lt; .001). While objective sleep was not linked to attention control, poorer between-person subjective sleep was associated with better postpartum attention control (β = − 0.84, <i>p</i> &lt; .001). Better within-person subjective sleep was associated with higher attention control during pregnancy (β = 0.87, <i>p</i> &lt; .001), but a negative interaction with time (β = -1.5, <i>p</i> = .001) suggests a reverse trend postpartum. Attention control did not predict postpartum psychological outcomes.</p><h3>Conclusion</h3><p>Cognitive recovery may occur by four months postpartum, although the observed improvement could reflect practice effect. The novel finding of a negative association between subjective sleep and postpartum attention control may indicate better adaptation to perceived poor sleep or heightened attunement to sleep fluctuations in women with higher attention control. Attention control did not predict psychological outcomes, suggesting other factors may be more critical for maternal coping postpartum.</p></div>","PeriodicalId":8369,"journal":{"name":"Archives of Women's Mental Health","volume":"28 3","pages":"613 - 622"},"PeriodicalIF":3.2,"publicationDate":"2024-11-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://link.springer.com/content/pdf/10.1007/s00737-024-01530-5.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142613749","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Severe alcohol withdrawal during pregnancy or early postpartum: maternal and fetal outcomes","authors":"Shaun Daidone,&nbsp;Hayrunnisa Unlu,&nbsp;Asmaa Yehia,&nbsp;Nan Zhang,&nbsp;Osama A. Abulseoud","doi":"10.1007/s00737-024-01531-4","DOIUrl":"10.1007/s00737-024-01531-4","url":null,"abstract":"<div><h3>Objective</h3><p>Alcohol withdrawal syndrome (AWS) during pregnancy is under-researched despite growing concerns about increased alcohol use among pregnant women. This study aims to explore the severity of AWS and its impact on maternal and fetal outcomes.</p><h3>Methods</h3><p>This retrospective study reviewed the medical records of patients admitted to the Mayo Clinic who underwent the CIWA-Ar protocol for AWS from June 2019 through June 2022. Pregnant women identified in this cohort had their pregnancy, labor, and neonatal data analyzed for alcohol-related complications and outcomes.</p><h3>Results</h3><p>Out of the medical records reviewed, 8 cases involved pregnant women experiencing AWS. These cases showed a high severity of withdrawal symptoms, with a median peak CIWA-Ar score of 17 (IQR = 14). Maternal complications included a high rate of ICU admissions (37.5%; n = 3) and significant rates of miscarriage and stillbirth (37.5%; n = 3). Fetal outcomes were concerning, with 1 out of 5 (20%) neonates requiring NICU admission and experiencing conditions such as respiratory failure and neonatal abstinence syndrome. Developmental problems were noted in 2 out of 5 (40%) newborns.</p><h3>Conclusions</h3><p>The findings highlight the severe implications of AWS during pregnancy, impacting both maternal and fetal health. The severity of AWS requires attentive clinical management and preventative interventions. Future research should focus on larger, prospective studies to better understand and address the risks associated with AWS in pregnant women and to improve health outcomes for mothers and their children.</p><h3>Article Highlights</h3><p>• Severe AWS during pregnancy leads to high ICU admissions and adverse neonatal outcomes.</p><p>• 37.5% of pregnant women with AWS experienced miscarriage or stillbirth.</p><p>• 20% of newborns from mothers with AWS required NICU admission for serious conditions; 40% of newborns had developmental problems.</p><p>• Findings underscore the need for specialized treatment protocols to improve outcomes for pregnant women and their newborns.</p></div>","PeriodicalId":8369,"journal":{"name":"Archives of Women's Mental Health","volume":"28 3","pages":"623 - 632"},"PeriodicalIF":3.2,"publicationDate":"2024-11-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://link.springer.com/content/pdf/10.1007/s00737-024-01531-4.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142613752","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}