Archivos De Bronconeumologia最新文献

{"title":"Screened vs. Non-Screened Lung Cancer: Real-World Evidence of a Stage Shift","authors":"Anna Sánchez-Cucó,&nbsp;Marcela Suárez,&nbsp;Sally Santisteve,&nbsp;Anna Vila,&nbsp;Carlos Manzano,&nbsp;Esther Gracia-Lavedan,&nbsp;Nerea Ramírez-Seco,&nbsp;Wasim el Arfaoui,&nbsp;María Zuil,&nbsp;Sònia Gatius,&nbsp;Carlos A. Rombolá,&nbsp;Marina Pardina,&nbsp;José David González,&nbsp;Ferran Barbé,&nbsp;Jessica González","doi":"10.1016/j.arbres.2026.02.013","DOIUrl":"10.1016/j.arbres.2026.02.013","url":null,"abstract":"<div><span><figure><span><img><ol><li><span><span>Download: <span>Download high-res image (182KB)</span></span></span></li><li><span><span>Download: <span>Download full-size image</span></span></span></li></ol></span></figure></span></div>","PeriodicalId":8339,"journal":{"name":"Archivos De Bronconeumologia","volume":"62 9","pages":"Pages 653-656"},"PeriodicalIF":8.7,"publicationDate":"2026-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147589495","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"From Lungs to Vascular Health: Airflow Obstruction, Not Lung Function Decline, Predicts Atherosclerosis Progression Independent of Smoking Status","authors":"Mario Henríquez-Beltrán,&nbsp;Esther Gracia-Lavedan,&nbsp;Anna Sánchez-Cucó,&nbsp;Gerard Torres,&nbsp;Adriano D.S. Targa,&nbsp;Marcelino Bermúdez-López,&nbsp;José Manuel Valdivielso,&nbsp;Reinald Pamplona,&nbsp;Dídac Mauricio,&nbsp;Eva Castro-Boqué,&nbsp;Elvira Fernández,&nbsp;Albert Lecube,&nbsp;Jordi de Batlle,&nbsp;Ferrán Barbé,&nbsp;Jessica González,&nbsp;on behalf of the ILERVAS project collaborators","doi":"10.1016/j.arbres.2026.04.012","DOIUrl":"10.1016/j.arbres.2026.04.012","url":null,"abstract":"<div><h3>Objectives</h3><div>To prospectively evaluate the relationship between 4-year changes in lung function and the progression of subclinical atherosclerosis among 1623 middle-aged adults with at least one cardiovascular risk factor participating in ILERVAS, and to determine whether individuals who develop airflow obstruction (AO) are especially susceptible to accelerated atherosclerosis progression.</div></div><div><h3>Methods</h3><div>This prospective cohort study included 1623 middle-aged adults from the ILERVAS cohort, recruited in primary care centers in the province of Lleida (Catalonia, Spain), with baseline assessments conducted between 2015 and 2018 and follow-up visits between 2019 and 2021 (mean follow-up, 3.99 [SD, 0.22] years). Pulmonary function was assessed by spirometry at baseline and at 4-year follow-up. Subclinical atherosclerosis was evaluated using vascular ultrasound of 12 carotid and femoral territories at baseline and at follow-up, with total plaque area quantified. Associations were analyzed using multivariable linear regression models, adjusting for clinical variables and baseline plaque burden. Analyses were stratified by smoking status.</div></div><div><h3>Results</h3><div>Median annual declines were −95<!--> <!-->mL (−2.04%) for FVC and −78<!--> <!-->mL (−2.00%) for FEV₁. Categorization of annual pulmonary function decline by tertiles showed no significant association with plaque progression. In contrast, incident AO was associated with greater annual FEV₁ decline (−146.73 vs −74.90<!--> <!-->mL; <em>P</em> <!-->&lt;<!--> <!-->.001) and with greater plaque burden, reflected by an increase in affected vascular territories (0.26 [IQR, 0.00–0.75]; <em>P</em> <!-->&lt;<!--> <!-->.001). Multivariable models confirmed larger annual increases in total (4.40<!--> <!-->mm²; <em>P</em> <!-->&lt;<!--> <!-->.001), carotid (2.33<!--> <!-->mm²; <em>P</em> <!-->&lt;<!--> <!-->.001), and femoral (1.99<!--> <!-->mm²; <em>P</em> <!-->=<!--> <!-->.031) plaque areas among participants with incident AO, with consistent results across smoking strata. Sensitivity analyses using a lower limit of normal-based definition of AO showed similar findings, with effect estimates consistent with the primary fixed-ratio analyses.</div></div><div><h3>Conclusions</h3><div>In this two-time-point analysis, lung function decline was not independently associated with subclinical atherosclerosis progression. In contrast, incident AO was consistently associated with greater plaque progression across smoking strata. These findings support incident AO as a spirometric marker associated with vascular risk.</div></div>","PeriodicalId":8339,"journal":{"name":"Archivos De Bronconeumologia","volume":"62 9","pages":"Pages 618-626"},"PeriodicalIF":8.7,"publicationDate":"2026-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147873209","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Integrated Assessment of CT-Derived Fibrosis Volume and Pulmonary Function in Identifying Progressive Pulmonary Fibrosis in Connective Tissue Disease-Associated Interstitial Lung Disease (CTD-ILD)","authors":"Kyongmin Sarah Beck,&nbsp;Nicola Sverzellati,&nbsp;Nicole Goh,&nbsp;Kyung Hoon Kim,&nbsp;Ji Weon Lee,&nbsp;Ahran Kim,&nbsp;Jung Hyun Nam,&nbsp;Jong Min Lee,&nbsp;Jeewon Lee,&nbsp;Yong Suk Jo","doi":"10.1016/j.arbres.2026.03.002","DOIUrl":"10.1016/j.arbres.2026.03.002","url":null,"abstract":"<div><span><figure><span><img><ol><li><span><span>Download: <span>Download high-res image (150KB)</span></span></span></li><li><span><span>Download: <span>Download full-size image</span></span></span></li></ol></span></figure></span></div>","PeriodicalId":8339,"journal":{"name":"Archivos De Bronconeumologia","volume":"62 9","pages":"Pages 661-664"},"PeriodicalIF":8.7,"publicationDate":"2026-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147715774","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Home NIV Software: Decision-support Tool or Digital Distraction?","authors":"Antoine Leotard, Patrick Brian Murphy","doi":"10.1016/j.arbres.2026.07.011","DOIUrl":"https://doi.org/10.1016/j.arbres.2026.07.011","url":null,"abstract":"","PeriodicalId":8339,"journal":{"name":"Archivos De Bronconeumologia","volume":" ","pages":""},"PeriodicalIF":8.7,"publicationDate":"2026-08-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148787627","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Hypercapnic Burden Derived From Nocturnal Transcutaneous CO₂ Measurement: A Preliminary Study in Patients With Slowly Progressive Neuromuscular Diseases.","authors":"Siham Benkerrou, Piotr Dolecki, Marie Anne Melone, Pierre Tankéré, Isabelle Bossard, Amélie Pillot, Maxime Patout, Guillaume Bao, Hélène Prigent, Antoine Leotard","doi":"10.1016/j.arbres.2026.07.010","DOIUrl":"https://doi.org/10.1016/j.arbres.2026.07.010","url":null,"abstract":"","PeriodicalId":8339,"journal":{"name":"Archivos De Bronconeumologia","volume":" ","pages":""},"PeriodicalIF":8.7,"publicationDate":"2026-08-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148787615","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Combined Assessment of Frailty and Respiratory Function in Idiopathic Pulmonary Fibrosis: A Prospective Cohort Study.","authors":"Chukwuma Okoye, Giovanni Franco, Isabella Ceravolo, Umberto Zanini, Riccardo Galluccio, Alice Margherita Ornago, Elisa Perger, Maria Cristina Ferrara, Camilla Tocci, Leonardo Barbieri, Alberto Finazzi, Paola Faverio, Antonella Zambon, Fabrizio Luppi, Giuseppe Bellelli","doi":"10.1016/j.arbres.2026.07.002","DOIUrl":"https://doi.org/10.1016/j.arbres.2026.07.002","url":null,"abstract":"<p><strong>Background: </strong>Idiopathic pulmonary fibrosis (IPF) predominantly affects older adults. Frailty is increasingly recognized as an important feature of IPF, although its prognostic value remains uncertain. This study aimed to assess the prevalence of frailty and concordance among validated instruments, characterize the principal domains of vulnerability identified through comprehensive geriatric assessment (CGA), and evaluate the prognostic value of integrating frailty with indices of respiratory disease severity in older adults with IPF.</p><p><strong>Methods: </strong>We conducted a prospective, single-center study of patients aged 65 years or older with confirmed IPF. Frailty was assessed using the Fried frailty phenotype (FFP), a CGA-derived Frailty Index (CGA-FI), and the Clinical Frailty Scale (CFS). The primary outcome was a composite of all-cause mortality or acute exacerbation during follow-up. Cox proportional hazards models and bootstrap-derived concordance indices were used to evaluate prognostic associations and model discrimination.</p><p><strong>Results: </strong>Among the 140 patients included, the prevalence of frailty ranged from 16.4% according to the CGA-FI to 22.3% according to the FFP, whereas 19.3% were classified as frail according to the CFS. During a median follow-up of 465 days (IQR, 221-1076 days), 35 patients (25.0%) experienced the composite outcome. Frailty assessed using the CFS (CFS ≥5: HR, 3.94; 95%CI, 1.81-8.58) and a higher Gender-Age-Physiology (GAP) stage (GAP II-III: HR, 3.11; 95%CI, 1.39-7.00) were independently associated with the composite outcome. The integrated GAP-CFS model showed good discrimination, with a bootstrap-derived Harrell C index of 0.72 (95%CI, 0.62-0.81). Patients who experienced events also had higher Strength, Assistance in Walking, Rising From a Chair, Climbing Stairs, and Falls (SARC-F) scores and greater functional impairment.</p><p><strong>Conclusions: </strong>Frailty is common and clinically relevant in IPF. Integrating frailty measures with pulmonary indices improves prognostic stratification and supports the use of the CFS and CGA to guide personalized, multidimensional care.</p>","PeriodicalId":8339,"journal":{"name":"Archivos De Bronconeumologia","volume":" ","pages":""},"PeriodicalIF":8.7,"publicationDate":"2026-08-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148757597","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Performance and Synchronization of Portable Oxygen Concentrators Delivering Pulsed Oxygen Therapy.","authors":"Marius Lebret, Emeline Fresnel, Jacqueline Delrieu, Maxime Patout, Claudio Rabec","doi":"10.1016/j.arbres.2026.07.009","DOIUrl":"10.1016/j.arbres.2026.07.009","url":null,"abstract":"<p><strong>Objectives: </strong>This study evaluated the performance of seven POCs, focusing on FiO₂, bolus triggering delay, synchronization, and technical specifications, including weight, size, noise level, and battery autonomy.</p><p><strong>Methods: </strong>A bench study was conducted using a mechanical lung model (ASL 5000) equipped with a Fast Oxygen Measurement sensor. Seven devices available on the European market were tested: FreeStyle Comfort, iGo2, Inogen One G4, Inogen One G5, Platinum Mobile, Zen-O lite, and Horizon P5. 200 ventilatory cycles were simulated per device across various respiratory rates (RR). Measurements included FiO₂, bolus triggering delay, synchronization, and bolus volume. Technical specifications were also compared. All devices were tested across their full range of settings, with each test replicated on a second device to confirm results within a 10% margin of error.</p><p><strong>Results: </strong>Significant differences in FiO₂ delivery were observed (p<0.001), with all devices delivering at least 28% FiO₂ at their lowest settings. The Inogen One G5 and Horizon P5 achieved the highest FiO₂ levels (48.7% [38.4-56.9%] and 47.8% [35.6-56.4%], respectively). Synchronization was high across devices but declined at extreme RR (15 and 40bpm). FiO₂ variations were influenced by RR, while bolus delays depended on device type and RR. Technical specifications varied widely across devices.</p><p><strong>Conclusions: </strong>POCs demonstrate notable differences in performance, with RR and device type impacting FiO₂ delivery and synchronization. These findings may help support more informed device selection according to the intended conditions of use and patient requirements.</p>","PeriodicalId":8339,"journal":{"name":"Archivos De Bronconeumologia","volume":" ","pages":""},"PeriodicalIF":8.7,"publicationDate":"2026-08-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148720455","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"EBV-associated Smooth Muscle Tumours in a Lung Transplant Patient.","authors":"Guillermo Rodríguez Dávila, Myriam Aguilar Pérez, Javier Martín López, Rosalia Laporta Hernández, Silvana Crowley Carrasco","doi":"10.1016/j.arbres.2026.07.007","DOIUrl":"10.1016/j.arbres.2026.07.007","url":null,"abstract":"","PeriodicalId":8339,"journal":{"name":"Archivos De Bronconeumologia","volume":" ","pages":""},"PeriodicalIF":8.7,"publicationDate":"2026-08-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148719945","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Mask-Type Switching Trajectories and CPAP Use in Long-Term Obstructive Sleep Apnoea: The SwitchAdene Real-World Cohort Study.","authors":"Celia Vidal, Jean-Pierre Mallet, Raphaël Gilson, Olivier Gaubert, Jean-Christian Borel, Frédéric Gagnadoux, Arnaud Prigent, Arnaud Bourdin, Nicolas Molinari, Dany Jaffuel","doi":"10.1016/j.arbres.2026.07.008","DOIUrl":"10.1016/j.arbres.2026.07.008","url":null,"abstract":"<p><strong>Objective: </strong>To characterise long-term mask-type trajectories among patients receiving continuous positive airway pressure (CPAP) and assess their associations with CPAP nonadherence and treatment termination.</p><p><strong>Methods: </strong>This real-world longitudinal cohort study included newly diagnosed adults treated with CPAP for more than 1 month. Patients had unrestricted access to 48 models across 4 mask types: nasal masks (NMs), oronasal masks (ONMs), and nasal-pillow masks (NPMs), with the latter subdivided into nasal-cradle masks (NCMs) and intranasal masks (INMs). Sequence analysis was used to identify mask trajectories, and multivariable models were used to estimate odds ratios (ORs) for CPAP nonadherence and treatment termination.</p><p><strong>Results: </strong>Among 4675 patients, the median duration of CPAP treatment was 1.5 years (IQR, 0.7-2.8 years); 21.8% were nonadherent, and 26.1% terminated treatment. Adherent patients changed mask type less frequently than nonadherent patients and those who terminated treatment (43.7% vs 50.4% and 53.8%, respectively; p<.001). NM use decreased from 72.3% to 43.1%, whereas ONM use increased from 19.8% to 37.0%, INM use from 2.4% to 6.5%, and NCM use from 5.5% to 13.4%. Fifteen trajectories were identified. Compared with NM renewal, ONM and INM renewal were not associated with a higher risk of nonadherence or treatment termination, whereas NCM renewal was associated with CPAP termination (OR, 1.60; 95%CI, 1.04-2.47; p=.034). Switching from an initial NM to an INM (OR, 1.68; 95%CI, 1.18-2.39; p=.004), NCM (OR, 1.76; 95%CI, 1.26-2.45; p=.001), or ONM (OR, 1.31; 95%CI, 1.01-1.70; p=.046) was associated with CPAP termination.</p><p><strong>Conclusions: </strong>In routine clinical practice, NM, ONM, and INM renewal trajectories were comparable, whereas NCM renewal was associated with unfavourable outcomes. Switching from an NM to an ONM or NPM was associated with poorer CPAP use. NCMs and INMs should not be pooled under the general NPM category.</p><p><strong>Trial registration: </strong>The SwitchAdene study is registered with the Health Data Hub under registration No. 19334378.</p>","PeriodicalId":8339,"journal":{"name":"Archivos De Bronconeumologia","volume":" ","pages":""},"PeriodicalIF":8.7,"publicationDate":"2026-08-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148719843","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Early Mepolizumab Plus Glucocorticoids in Newly Diagnosed Eosinophilic Granulomatosis With Polyangiitis: A 52-Week Multicenter Retrospective Cohort Study.","authors":"Ignacio Boira, Néstor Rodríguez-Melean, Leticia De Las Vecillas, David Romero, Ana Noblejas, Andrea Trisán, Violeta Esteban-Ronda, Elena Villamañán, Javier Dominguez-Ortega, Luis Gómez-Carrera, Ignacio Robles-Barrena, Santiago Quirce, Rodolfo Álvarez-Sala, Eusebi Chiner, Daniel Laorden","doi":"10.1016/j.arbres.2026.07.012","DOIUrl":"10.1016/j.arbres.2026.07.012","url":null,"abstract":"","PeriodicalId":8339,"journal":{"name":"Archivos De Bronconeumologia","volume":" ","pages":""},"PeriodicalIF":8.7,"publicationDate":"2026-08-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148719814","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}