Archivos De Bronconeumologia最新文献

{"title":"CO1","authors":"","doi":"10.1016/S0300-2896(25)00195-4","DOIUrl":"10.1016/S0300-2896(25)00195-4","url":null,"abstract":"","PeriodicalId":8339,"journal":{"name":"Archivos De Bronconeumologia","volume":"61 7","pages":"Page CO1"},"PeriodicalIF":8.7,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144523149","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A 46-Year-Old Female With a Left Bronchial Neoplasm Swaying With Respiration.","authors":"Qinglin Zhong, Binglin Lai","doi":"10.1016/j.arbres.2025.06.013","DOIUrl":"https://doi.org/10.1016/j.arbres.2025.06.013","url":null,"abstract":"","PeriodicalId":8339,"journal":{"name":"Archivos De Bronconeumologia","volume":" ","pages":""},"PeriodicalIF":8.7,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144641625","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Microbiome, Metabolome and Complexity in Bronchiectasis: The Future is Here","authors":"Grace Oscullo , Amina Bekki , Miguel Angel Martinez-Garcia","doi":"10.1016/j.arbres.2025.01.009","DOIUrl":"10.1016/j.arbres.2025.01.009","url":null,"abstract":"","PeriodicalId":8339,"journal":{"name":"Archivos De Bronconeumologia","volume":"61 7","pages":"Pages 391-392"},"PeriodicalIF":8.7,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143413277","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Sputum Microbiota Correlates With Metabolome and Clinical Outcomes in Asthma–Bronchiectasis Overlap","authors":"Xiao-xian Zhang ,&nbsp;Zhen-feng He ,&nbsp;Jia-hui He ,&nbsp;Zhao-ming Chen ,&nbsp;Cui-xia Pan ,&nbsp;Zhen-hong Lin ,&nbsp;Lai-jian Cen ,&nbsp;Hui-min Li ,&nbsp;Yan Huang ,&nbsp;Ming-xin Shi ,&nbsp;Wei-jie Guan","doi":"10.1016/j.arbres.2025.01.002","DOIUrl":"10.1016/j.arbres.2025.01.002","url":null,"abstract":"<div><h3>Objectives</h3><div>To investigate the microbiota and metabolome of patients with ABO compared with bronchiectasis and asthma, and determine the relevance with clinical characteristics, inflammatory endotype and exacerbation risks.</div></div><div><h3>Methods</h3><div>In this prospective cohort study, patients underwent comprehensive assessments, including sputum differential cell count, and sputum collection at baseline. Sputum microbiota was profiled via 16S rRNA gene sequencing and metabolome via liquid chromatography/mass spectrometry. Shannon-Wiener Diversity Index (SWDI) was used to reflect dysbiosis. Patients were followed-up to record exacerbations. ABO patients were stratified by the SWDI and sputum eosinophilia to determine the exacerbation risks.</div></div><div><h3>Results</h3><div>Two hundred forty-seven patients were recruited, including 99 ABO (median age: 53.2 years, 65.7% female), 61 asthma (median age: 39.5 years, 50.8% female) and 87 bronchiectasis patients (median age: 52.3 years, 55.2% female). Both microbiota compositions and metabolites differed among asthma, ABO and bronchiectasis, and between eosinophilic and non-eosinophilic ABO at steady-state. Baseline SWDI of microbiota was highest in asthma, followed by ABO. Both <em>Pseudomonadaceae</em> and <em>Rothia</em> most effectively discriminated ABO from asthma and bronchiectasis. <em>Pseudomonas</em> exhibited a more pronounced negative correlation with other taxa in nonEos-ABO. ABO patients with low SWDI with sputum eosinophilia, or those with high SWDI without sputum eosinophilia, had a shorter time to the first exacerbation. Metabolomic compositions in Eos-ABO separated from nonEos-ABO. The relative abundance of <em>Enterobacteriaceae</em> correlated negatively with 15-hydroxylated eicosatetraenoic acid, whose concentrations were higher in Eos-ABO.</div></div><div><h3>Conclusions</h3><div>Integrating microbiota and metabolome profiles, together with eosinophilic inflammatory endotyping, can inform exacerbation risk and personalized management of ABO.</div></div>","PeriodicalId":8339,"journal":{"name":"Archivos De Bronconeumologia","volume":"61 7","pages":"Pages 417-426"},"PeriodicalIF":8.7,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142969379","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Risk Factors and Outcomes Associated With Polymicrobial Infection in Community-Acquired Pneumonia","authors":"Catia Cillóniz ,&nbsp;Davide Calabretta ,&nbsp;Andrea Palomeque ,&nbsp;Albert Gabarrus ,&nbsp;Miquel Ferrer ,&nbsp;María Ángeles Marcos ,&nbsp;Antoni Torres","doi":"10.1016/j.arbres.2025.01.001","DOIUrl":"10.1016/j.arbres.2025.01.001","url":null,"abstract":"<div><h3>Background</h3><div>Polymicrobial pneumonia is a concern for clinicians due to its association with increased disease severity. Determining the prevalence of polymicrobial pneumonia and identifying patients who have an increased risk of this aetiology is important for the management of CAP patients. Here we describe the clinical characteristics and outcomes of adult hospitalized patients with CAP, and identify the risk factors related to polymicrobial pneumonia and specifically to 30-day mortality.</div></div><div><h3>Methods</h3><div>Real-life retrospective study from a prospectively collected data including 5114 consecutive adult patients hospitalized with CAP; 1703 patients had an established aetiology.</div></div><div><h3>Results</h3><div>Polymicrobial infection was present in 14% of the CAP patients with defined microbial aetiology (64% of ward patients and 28% of ICU patients). The most frequent polymicrobial infections were: <em>Streptococcus pneumoniae</em> <!-->+<!--> <!-->respiratory virus (32%), <em>S. pneumoniae</em> <!-->+<!--> <em>Haemophilus influenzae</em> (7%) and <em>S. pneumoniae</em> <!-->+<!--> <em>Staphylococcus aureus</em> (7%). Inappropriate initial antimicrobial treatment was more frequent in the polymicrobial aetiology group than in the monomicrobial aetiology group (14% vs. 7%, <em>p</em> <!-->=<!--> <!-->0.001). In-hospital (12% vs. 7%, <em>p</em> <!-->=<!--> <!-->0.012), 30-day (11% vs. 6%, <em>p</em> <!-->=<!--> <!-->0.008) and 1-year mortality (16% vs. 8%, <em>p</em> <!-->=<!--> <!-->0.001) were higher in the polymicrobial group. Multilobar pneumonia (OR 1.34, 95% CI 1.00–1.80) was an independent risk factor for polymicrobial aetiology in the multivariable analysis, while fever (OR 0.59, 95% CI 0.43–0.80) was independently associated with a lower risk for this condition. Polymicrobial infection was an independent predictor of 30-day mortality in the multivariable analysis (HR 1.83, 95% CI 1.17–2.87; <em>p</em> <!-->=<!--> <!-->0.008).</div></div><div><h3>Conclusions</h3><div>Polymicrobial infection was related to poor outcomes in adults hospitalized with CAP, especially in elderly patients with chronic comorbidities. Polymicrobial infection was a risk factor for 30-day mortality.</div></div>","PeriodicalId":8339,"journal":{"name":"Archivos De Bronconeumologia","volume":"61 7","pages":"Pages 408-416"},"PeriodicalIF":8.7,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142982422","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Is Obstructive Sleep Apnea in People Without Obesity a Unique Disease?","authors":"Atul Malhotra ,&nbsp;Ana Lucia Fuentes ,&nbsp;Bradley A. Edwards","doi":"10.1016/j.arbres.2025.02.014","DOIUrl":"10.1016/j.arbres.2025.02.014","url":null,"abstract":"","PeriodicalId":8339,"journal":{"name":"Archivos De Bronconeumologia","volume":"61 7","pages":"Pages 393-394"},"PeriodicalIF":8.7,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143673437","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The Future of Sleep Apnea Research: From Foundational Discoveries to Personalized Medicine.","authors":"Monica Levy Andersen, Sergio Brasil Tufik, Sergio Tufik","doi":"10.1016/j.arbres.2025.06.011","DOIUrl":"https://doi.org/10.1016/j.arbres.2025.06.011","url":null,"abstract":"","PeriodicalId":8339,"journal":{"name":"Archivos De Bronconeumologia","volume":" ","pages":""},"PeriodicalIF":8.7,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144641628","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Unplanned Reoperation After Anatomical Pulmonary Resection for Lung Cancer: Rate, Risk Factors, Early Outcomes and Long-term Prognostic Influence Within a Prospective Multicentre Database","authors":"Maria Teresa Gómez-Hernández ,&nbsp;Cristina Rivas ,&nbsp;Gonzalo Varela ,&nbsp;Marcelo Jiménez ,&nbsp;on behalf of the Spanish Group of Video-assisted Thoracic Surgery (GEVATS)","doi":"10.1016/j.arbres.2025.01.003","DOIUrl":"10.1016/j.arbres.2025.01.003","url":null,"abstract":"<div><h3>Objectives</h3><div>The study aimed to identify perioperative variables associated with unplanned reoperation (UR) following anatomical pulmonary resection for lung cancer and investigate its impact on long-term prognostic outcomes.</div></div><div><h3>Methods</h3><div>The records of patients who underwent anatomical pulmonary resection for lung cancer from December 2016 to March 2018 within a nationwide prospective registry were reviewed. Multivariable logistic regression analyses were performed to find the risk factors for UR. The short-term outcomes were compared, and the adjusted odds ratios for in-hospital and 90-day mortality were calculated. The prognostic value of UR for overall survival (OS) and disease-free survival (DFS) was assessed using the Kaplan–Meier method and log-rank test after propensity score matching for balancing baseline confounders.</div></div><div><h3>Results</h3><div>Data from 3085 patients were examined, revealing a UR incidence of 4.12%. Multivariable logistic regression analyses revealed that male gender (OR<!--> <!-->=<!--> <!-->3.288, <em>P</em> <!-->=<!--> <!-->0.004), ppoDLCO% (OR<!--> <!-->=<!--> <!-->0.975, <em>P</em> <!-->=<!--> <!-->0.003), pneumonectomy (OR<!--> <!-->=<!--> <!-->4.748, <em>P</em> <!-->=<!--> <!-->0.038), strong pleural adhesions (OR<!--> <!-->=<!--> <!-->3.449, <em>P</em> <!-->&lt;<!--> <!-->0.001) and hospital volume ≥150 cases (OR<!--> <!-->=<!--> <!-->1.75, <em>P</em> <!-->=<!--> <!-->0.026) were independently associated with UR. Risk of in-hospital and 90-day mortality was higher in UR cases (adjusted OR<!--> <!-->=<!--> <!-->7.312, <em>P</em> <!-->&lt;<!--> <!-->0.001, and OR<!--> <!-->=<!--> <!-->5.188, <em>P</em> <!-->&lt;<!--> <!-->0.001, respectively). Ninety-eight UR and 347 matched non-UR cases were included in the long-term follow-up analysis. The median follow-up time was 50.4 months. No significant differences were found in OS, and DFS between groups (log rank <em>P</em> <!-->=<!--> <!-->0.953 and <em>P</em> <!-->=<!--> <!-->0.352, respectively).</div></div><div><h3>Conclusion</h3><div>Male gender, ppoDLCO%, pneumonectomy, strong pleural adhesions, and surgical unit workload were all independently associated with UR. UR was associated with an increased perioperative mortality, but not with a higher long-term mortality.</div></div>","PeriodicalId":8339,"journal":{"name":"Archivos De Bronconeumologia","volume":"61 7","pages":"Pages 427-433"},"PeriodicalIF":8.7,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143036279","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Out With the Old, in With the New: What Changes in the 9th Edition of the TNM Classification for Lung Cancer?","authors":"Ramón Rami-Porta ,&nbsp;Hisao Asamura ,&nbsp;Valerie W. Rusch","doi":"10.1016/j.arbres.2025.02.016","DOIUrl":"10.1016/j.arbres.2025.02.016","url":null,"abstract":"","PeriodicalId":8339,"journal":{"name":"Archivos De Bronconeumologia","volume":"61 7","pages":"Pages 395-397"},"PeriodicalIF":8.7,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143690961","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Early Nirsevimab Administration During Hospitalization for RSV Bronchiolitis may Reduce Disease Severity in Non-immunized infants: A Descriptive Study.","authors":"Ana Méndez-Echevarria, Jose Antonio Soler-Simón, Eva Simón Carro, Patricia Flores Pérez, Raquel Jiménez García, Begoña Sánchez-Rico Lucas-Torres, María Tejada Pérez, Sonia Alcolea, María Luz García-García, Fernando Baquero-Artigao, Cristina Calvo","doi":"10.1016/j.arbres.2025.06.010","DOIUrl":"https://doi.org/10.1016/j.arbres.2025.06.010","url":null,"abstract":"","PeriodicalId":8339,"journal":{"name":"Archivos De Bronconeumologia","volume":" ","pages":""},"PeriodicalIF":8.7,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144641626","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}